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DESCRIPTION
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Package: EPICATAC
Type: Package
Title: Estimate the Proportion of Immune and Cancer cells in ATAC-Seq data
Version: 1.0
Authors@R: as.person(c(
"Aurélie Gabriel <aurelie.gabriel@unil.ch> [aut, cre]",
"Julien Racle <julien.racle@unil.ch> [aut]",
"David Gfeller <david.gfeller@unil.ch> [aut]"
))
Description: Package implementing EPIC method to estimate the proportion of
immune, stromal, endothelial and cancer or other cells from bulk chromatin accessibility or gene
expression data.
It is based on reference profiles for the main non-malignant
cell types and it predicts the proportion of these cells and of the
remaining "other cells" (that are mostly cancer cells) for which no
reference profile is given.
Depends:
R (>= 4.1)
License: file LICENSE
Encoding: UTF-8
LazyData: TRUE
RoxygenNote: 7.2.3
biocViews:
Software, ExperimentData, Annotation
Suggests:
testthat,
knitr,
rmarkdown,
remotes
Imports:
stats,
GenomicRanges,
rtracklayer,
tidyr,
GenomeInfoDb,
S4Vectors
VignetteBuilder: knitr