diff --git a/changelog.md b/changelog.md
index 2d1994cdf..5ceb6d723 100644
--- a/changelog.md
+++ b/changelog.md
@@ -9,6 +9,9 @@ and (starting with v4.0.0) this project adheres to [Semantic Versioning](http://
 
 ## [Released](https://github.com/HumanCellAtlas/metadata-schema/)
 
+### [system/file_descriptor.json - v2.1.0] - 2024-09-24
+### Added
+Added 'drs_uri' property to file_descriptor
 
 ### [module/biomaterial/medical_history.json - v5.3.0] - 2024-09-16
 ### Added
diff --git a/json_schema/system/file_descriptor.json b/json_schema/system/file_descriptor.json
index 6d62f3d73..949a36bca 100644
--- a/json_schema/system/file_descriptor.json
+++ b/json_schema/system/file_descriptor.json
@@ -94,6 +94,13 @@
       "user_friendly": "S3 ETag",
       "type": "string",
       "example": "c92e5374ac0a53b228d4c1511c2d2842-63"
+    },
+    "drs_uri": {
+      "description": "Data Repository Service URI pointing at this file. If this property is absent, a data file exists in the repository containing this descriptor. If this property is present and not `null`, a data file exists in another repository at the specified URI. If this property is present but `null`, the data file is not available, but will likely become available in the future, along with an updated descriptor referencing it.",
+      "user_friendly": "Data Repository Service URI",
+      "type": ["string", "null"],
+      "format": "uri",
+      "example": "drs://drs.example.org/314159"
     }
   }
 }
\ No newline at end of file
diff --git a/json_schema/versions.json b/json_schema/versions.json
index 27bebe930..5cec5fd99 100644
--- a/json_schema/versions.json
+++ b/json_schema/versions.json
@@ -1,5 +1,5 @@
 {
-    "last_update_date": "2024-09-16T14:52:03Z",
+    "last_update_date": "2024-09-24T15:16:27Z",
     "version_numbers": {
         "core": {
             "biomaterial": {
@@ -83,7 +83,7 @@
             }
         },
         "system": {
-            "file_descriptor": "2.0.0",
+            "file_descriptor": "2.1.0",
             "license": "1.0.0",
             "links": "3.1.0",
             "provenance": "1.1.0"