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This job just started failing within the past few days, and happens very consistently, possibly 100% of the time. See eg this CI run.
The failure looks to be a bad interaction between pytest and venvs. This pytest issue seems relevant: pytest-dev/pytest#8935. I don't think it's pyodide-specific, though I could be wrong. To my knowledge we haven't bumped pyodide or pytest recently (though we did just update other deps: #4305).