I posted a possible solution for my setup, where the T265 failed to enumerate after boot. In my case, it turned out to be a power supply issue. https://geekworm.com/products/nvidia-jetson-nano18650-ups-power-management-expansion-board-t200 https://github.com/IntelRealSense/librealsense/issues/5113 Hope it helps someone else! Cheers