diff --git a/N/NeoPKPDCore/Compat.toml b/N/NeoPKPDCore/Compat.toml
new file mode 100644
index 000000000000000..8d19ad45441184e
--- /dev/null
+++ b/N/NeoPKPDCore/Compat.toml
@@ -0,0 +1,15 @@
+[0]
+AdvancedHMC = "0.6"
+DifferentialEquations = "7.17.0 - 7"
+Distributions = "0.25.122 - 0.25"
+ForwardDiff = "1"
+JSON = "1.3.0 - 1"
+JSON3 = "1"
+LineSearches = "7"
+NLopt = "1"
+Optim = "1"
+ReverseDiff = "1"
+SciMLBase = "2.131.0 - 2"
+SpecialFunctions = "2"
+StableRNGs = "1.0.4 - 1"
+StaticArrays = "1.9.16 - 1"
diff --git a/N/NeoPKPDCore/Deps.toml b/N/NeoPKPDCore/Deps.toml
new file mode 100644
index 000000000000000..5e8a154ad1e5dd1
--- /dev/null
+++ b/N/NeoPKPDCore/Deps.toml
@@ -0,0 +1,24 @@
+[0]
+AdvancedHMC = "0bf59076-c3b1-5ca4-86bd-e02cd72cde3d"
+Dates = "ade2ca70-3891-5945-98fb-dc099432e06a"
+DifferentialEquations = "0c46a032-eb83-5123-abaf-570d42b7fbaa"
+Distributions = "31c24e10-a181-5473-b8eb-7969acd0382f"
+ForwardDiff = "f6369f11-7733-5829-9624-2563aa707210"
+JSON = "682c06a0-de6a-54ab-a142-c8b1cf79cde6"
+JSON3 = "0f8b85d8-7281-11e9-16c2-39a750bddbf1"
+LineSearches = "d3d80556-e9d4-5f37-9878-2ab0fcc64255"
+LinearAlgebra = "37e2e46d-f89d-539d-b4ee-838fcccc9c8e"
+NLopt = "76087f3c-5699-56af-9a33-bf431cd00edd"
+Optim = "429524aa-4258-5aef-a3af-852621145aeb"
+Pkg = "44cfe95a-1eb2-52ea-b672-e2afdf69b78f"
+Printf = "de0858da-6303-5e67-8744-51eddeeeb8d7"
+Random = "9a3f8284-a2c9-5f02-9a11-845980a1fd5c"
+ReverseDiff = "37e2e3b7-166d-5795-8a7a-e32c996b4267"
+SHA = "ea8e919c-243c-51af-8825-aaa63cd721ce"
+SciMLBase = "0bca4576-84f4-4d90-8ffe-ffa030f20462"
+SpecialFunctions = "276daf66-3868-5448-9aa4-cd146d93841b"
+StableRNGs = "860ef19b-820b-49d6-a774-d7a799459cd3"
+StaticArrays = "90137ffa-7385-5640-81b9-e52037218182"
+Statistics = "10745b16-79ce-11e8-11f9-7d13ad32a3b2"
+Test = "8dfed614-e22c-5e08-85e1-65c5234f0b40"
+UUIDs = "cf7118a7-6976-5b1a-9a39-7adc72f591a4"
diff --git a/N/NeoPKPDCore/Package.toml b/N/NeoPKPDCore/Package.toml
new file mode 100644
index 000000000000000..7bbca76a6eb916a
--- /dev/null
+++ b/N/NeoPKPDCore/Package.toml
@@ -0,0 +1,4 @@
+name = "NeoPKPDCore"
+uuid = "aa42e64f-7c0c-4f7e-9a43-9f30a48e1a32"
+repo = "https://github.com/shramish2057/neopkpd.git"
+subdir = "packages/core"
diff --git a/N/NeoPKPDCore/Versions.toml b/N/NeoPKPDCore/Versions.toml
new file mode 100644
index 000000000000000..341a93f2ce7d28a
--- /dev/null
+++ b/N/NeoPKPDCore/Versions.toml
@@ -0,0 +1,2 @@
+["0.1.0"]
+git-tree-sha1 = "41261962c3bad7f891aca64237f46947e6992160"
diff --git a/Registry.toml b/Registry.toml
index 508c0aa091704a1..8bd4e7b16f4a881 100644
--- a/Registry.toml
+++ b/Registry.toml
@@ -8758,6 +8758,7 @@ aa3a806a-e146-4a0b-abc5-6bb34b5dedb7 = { name = "PermutedArrays", path = "P/Perm
 aa3b323a-0e68-4b14-b952-9911d94e084a = { name = "OceanDistributions", path = "O/OceanDistributions" }
 aa41a628-2c43-45df-899b-83ab96621781 = { name = "OrthogonalPolynomialsQuasi", path = "O/OrthogonalPolynomialsQuasi" }
 aa41fe3f-f84b-5278-bb8c-b34b17f07c6c = { name = "GenICamRuntime_jll", path = "jll/G/GenICamRuntime_jll" }
+aa42e64f-7c0c-4f7e-9a43-9f30a48e1a32 = { name = "NeoPKPDCore", path = "N/NeoPKPDCore" }
 aa4a32ff-dd5d-5357-90e3-e7a9512f0501 = { name = "SimpleHypergraphs", path = "S/SimpleHypergraphs" }
 aa547a04-dd37-49ab-8e73-656744f8a8fc = { name = "DataDrop", path = "D/DataDrop" }
 aa5a021a-6c35-4f46-b189-2143d43923dc = { name = "Waluigi", path = "W/Waluigi" }