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Showcase new features of layer_stat_cor_plot() on the spatial registration vignette
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vignettes/guide_to_spatial_registration.Rmd

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@@ -239,24 +239,18 @@ sce_modeling_results <- registration_wrapper(
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```
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## Extract Enrichment t-statistics
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```{r "extract_t_stats"}
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## extract t-statics and rename
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registration_t_stats <- sce_modeling_results$enrichment[, grep("^t_stat", colnames(sce_modeling_results$enrichment))]
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colnames(registration_t_stats) <- gsub("^t_stat_", "", colnames(registration_t_stats))
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## cell types x gene
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dim(registration_t_stats)
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## check out table
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registration_t_stats[1:5, 1:5]
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```{r "extract_t_stats"}
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## check out table on enrichment t-statistics
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sce_modeling_results$enrichment[1:5, 1:5]
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```
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## Correlate statsics with Layer Reference
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```{r "layer_stat_cor"}
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cor_layer <- layer_stat_cor(
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stats = registration_t_stats,
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stats = sce_modeling_results$enrichment,
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modeling_results = layer_modeling_results,
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model_type = "enrichment",
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top_n = 100
@@ -301,6 +295,22 @@ anno <- annotate_registered_clusters(
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anno
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```
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## Plot Annotated Cell Types
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Finally, we can update our heatmap with colors and annotations based on cluster
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registration for the snRNA-seq clusters.
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```{r "plot_anno"}
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layer_stat_cor_plot(
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cor_layer,
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query_colors = get_colors(clusters = rownames(cor_layer)),
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reference_colors = libd_layer_colors,
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annotation = anno,
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cluster_rows = FALSE,
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cluster_columns = FALSE
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)
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```
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# Reproducibility
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