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GG4Search

Possible quadruplex-forming G-rich sequences finder (DNA)

Grab sequences with the following criteria (not for prediction)

Searching criteria: Gn1Nx1Gn2Nx2Gn3Nx3Gn4; n>=2 <see reference 1>

python GG4Search.py -i inputpath -o outputpath -c seq

# -i --input "Input-file to be analyzed. Format accepted is csv"
# -o --output "Path to output analyzed data"
# -c --column "The name of column containg DNA sequences"

This tool helps you filter DNA sequences with searching criterial, and outputs the GG counts >=4 in a csv file

Reference

  1. Puig Lombardi, Emilia, and Arturo Londoño-Vallejo. “A guide to computational methods for G-quadruplex prediction.” Nucleic acids research vol. 48,1 (2020): 1-15. doi:10.1093/nar/gkz1097