Using either a US or EU Mega CD model 1 BIOS (region patched or untouched), the looping animated BIOS screen will automatically go to the CD player after approximately 10 seconds. If a game is loaded, it will automatically start in around the same amount of time. Neither of these things happen with JP model 1 BIOS or any model 2 BIOS.
This bug has been confirmed by at least 2 other users:
https://misterfpga.org/viewtopic.php?p=89532
Real hardware will sit animated BIOS screen indefinitely and will not switch to the CD player unless a button is pressed.
The MegaCD core didn't used to do this (it used to act like real hardware), but I can't say for sure when this issue started.