https://markupsafe.palletsprojects.com/en/2.1.x/changes/#version-2-1-0

Error, if you need it: ImportError: cannot import name 'soft_unicode' from 'markupsafe' (/usr/local/Caskroom/miniconda/base/lib/python3.8/site-packages/markupsafe/__init__.py)

I can open/submit a PR in a few hours fixing this, just now right now. This will break any installations past 17 Feb 2022, so it seems rather high-priority.