diff --git a/platform/core/src/classes/MetadataProvider.ts b/platform/core/src/classes/MetadataProvider.ts
index 541d9ff30d2..16ec357faa0 100644
--- a/platform/core/src/classes/MetadataProvider.ts
+++ b/platform/core/src/classes/MetadataProvider.ts
@@ -551,7 +551,13 @@ const WADO_IMAGE_LOADER = {
       usingDefaultValues = true;
     }
 
-    if (ImageOrientationPatient) {
+    // Additional validation (1. Must exist, 2.Must be an array, 3.Must be 6 values, 4. Must not be an invalid array (all 0s))
+    if (
+      ImageOrientationPatient &&
+      Array.isArray(ImageOrientationPatient) &&
+      ImageOrientationPatient.length === 6 &&
+      ImageOrientationPatient.some(val => parseFloat(val) !== 0)
+    ) {
       rowCosines = toNumber(ImageOrientationPatient.slice(0, 3));
       columnCosines = toNumber(ImageOrientationPatient.slice(3, 6));
       imageOrientationPatient = toNumber(ImageOrientationPatient);