diff --git a/pcsx2/GS/Renderers/DX11/GSDevice11.cpp b/pcsx2/GS/Renderers/DX11/GSDevice11.cpp
index 0fd88f9d53715..07cbc3f24181d 100644
--- a/pcsx2/GS/Renderers/DX11/GSDevice11.cpp
+++ b/pcsx2/GS/Renderers/DX11/GSDevice11.cpp
@@ -2447,7 +2447,10 @@ void GSDevice11::VSSetShader(ID3D11VertexShader* vs, ID3D11Buffer* vs_cb)
 void GSDevice11::PSSetShaderResource(int i, GSTexture* sr)
 {
 	// Update local state only, PSUpdateShaderState updates gpu state.
-	m_state.ps_pending_srv[i] = *static_cast<GSTexture11*>(sr);
+	if (sr)
+		m_state.ps_pending_srv[i] = *static_cast<GSTexture11*>(sr);
+	else
+		m_state.ps_pending_srv[i] = nullptr;
 }
 
 void GSDevice11::PSSetSamplerState(ID3D11SamplerState* ss0)
diff --git a/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.cpp b/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.cpp
index 73a4dbb939586..57a98d28bfc07 100644
--- a/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.cpp
+++ b/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.cpp
@@ -2153,7 +2153,7 @@ void GSDeviceOGL::PSSetShaderResource(int i, GSTexture* sr)
 {
 	pxAssert(i < static_cast<int>(std::size(GLState::tex_unit)));
 
-	const GLuint id = static_cast<GSTextureOGL*>(sr)->GetID();
+	const GLuint id = sr ?  static_cast<GSTextureOGL*>(sr)->GetID() : 0;
 	if (GLState::tex_unit[i] != id)
 	{
 		GLState::tex_unit[i] = id;
@@ -2855,10 +2855,7 @@ void GSDeviceOGL::RenderHW(GSHWDrawConfig& config)
 	// Clear texture binding when it's bound to RT or DS.
 	if (!config.tex && ((draw_rt && static_cast<GSTextureOGL*>(draw_rt)->GetID() == GLState::tex_unit[0]) ||
 		(draw_ds && static_cast<GSTextureOGL*>(draw_ds)->GetID() == GLState::tex_unit[0])))
-	{
-		GLState::tex_unit[0] = 0;
-		glBindTextureUnit(0, 0);
-	}
+		PSSetShaderResource(0, nullptr);
 
 	// Avoid changing framebuffer just to switch from rt+depth to rt and vice versa.
 	bool fb_optimization_needs_barrier = false;