|
607 | 607 | "maximumSize": 250, |
608 | 608 | "enumValues": [ |
609 | 609 | { |
610 | | - "value": "TREM2", |
| 610 | + "value": "AB42", |
| 611 | + "description": "", |
| 612 | + "source": "" |
| 613 | + }, |
| 614 | + { |
| 615 | + "value": "APOE4 KI", |
| 616 | + "description": "humanized ApoE knock-in", |
| 617 | + "source": "https://www.jax.org/strain/027894" |
| 618 | + }, |
| 619 | + { |
| 620 | + "value": "APOE4Trem2R47H", |
| 621 | + "description": "double mutant with humanized ApoE knock-in mutation and an R47H point mutation of Trem2", |
| 622 | + "source": "https://www.jax.org/strain/028709" |
| 623 | + }, |
| 624 | + { |
| 625 | + "value": "APPE693Q", |
611 | 626 | "description": "", |
612 | 627 | "source": "" |
613 | 628 | }, |
614 | 629 | { |
615 | | - "value": "TYROBP", |
| 630 | + "value": "APPKM650", |
616 | 631 | "description": "", |
617 | 632 | "source": "" |
618 | 633 | }, |
619 | 634 | { |
620 | | - "value": "AB42", |
| 635 | + "value": "APPKM670", |
621 | 636 | "description": "", |
622 | 637 | "source": "" |
623 | 638 | }, |
624 | 639 | { |
625 | | - "value": "CRND8", |
| 640 | + "value": "APPKM670-671NL-PSEN1deltaexon9", |
626 | 641 | "description": "", |
627 | 642 | "source": "" |
628 | 643 | }, |
|
632 | 647 | "source": "https://www.jax.org/strain/005864" |
633 | 648 | }, |
634 | 649 | { |
635 | | - "value": "MAPT-P301K", |
| 650 | + "value": "CRND8", |
636 | 651 | "description": "", |
637 | 652 | "source": "" |
| 653 | + }, |
| 654 | + { |
| 655 | + "value": "C57BL6J", |
| 656 | + "description": "general purpose background strain", |
| 657 | + "source": "https://www.jax.org/strain/000664" |
| 658 | + }, |
| 659 | + { |
| 660 | + "value": "hAbeta KI", |
| 661 | + "description": "triple mutant strain with humanized ApoE knock-in, a mutant App gene, and an R47H point mutation of Trem2", |
| 662 | + "source": "https://www.jax.org/strain/030670" |
| 663 | + }, |
| 664 | + { |
| 665 | + "value": "hTauTrem2", |
| 666 | + "description": "expresses six isoforms of the human tau protein under the control of the endogenous human MAPT promoter backcrossed into Trem2 −/−mice", |
| 667 | + "source": "https://www.synapse.org/#!Synapse:syn18693211" |
638 | 668 | }, |
639 | 669 | { |
640 | | - "value": "rTg4510", |
| 670 | + "value": "MAPT-P301K", |
641 | 671 | "description": "", |
642 | 672 | "source": "" |
643 | 673 | }, |
644 | 674 | { |
645 | | - "value": "APPE693Q", |
| 675 | + "value": "rTg4510", |
646 | 676 | "description": "", |
647 | 677 | "source": "" |
648 | 678 | }, |
649 | 679 | { |
650 | | - "value": "APPKM650", |
| 680 | + "value": "TREM2", |
651 | 681 | "description": "", |
652 | 682 | "source": "" |
| 683 | + }, |
| 684 | + { |
| 685 | + "value": "Trem2R47H", |
| 686 | + "description": "mutant with an R47H point mutation of Trem2", |
| 687 | + "source": "https://www.jax.org/strain/027918" |
653 | 688 | }, |
654 | 689 | { |
655 | | - "value": "APPKM670", |
| 690 | + "value": "TYROBP", |
656 | 691 | "description": "", |
657 | 692 | "source": "" |
658 | 693 | }, |
659 | 694 | { |
660 | | - "value": "APPKM670-671NL-PSEN1deltaexon9", |
| 695 | + "value": "TYROBP_KO.KO", |
661 | 696 | "description": "", |
662 | 697 | "source": "" |
663 | | - }, |
| 698 | + }, |
664 | 699 | { |
665 | 700 | "value": "TYROBP_WT", |
666 | 701 | "description": "", |
|
671 | 706 | "description": "", |
672 | 707 | "source": "" |
673 | 708 | }, |
674 | | - { |
675 | | - "value": "TYROBP_KO.KO", |
676 | | - "description": "", |
677 | | - "source": "" |
678 | | - }, |
679 | 709 | { |
680 | 710 | "value": "5XFAD", |
681 | 711 | "description": "transgenic mice overexpressing three human APP mutations and two human PS1 FAD mutations", |
682 | 712 | "source": "https://www.jax.org/strain/008730" |
683 | | - }, |
684 | | - { |
685 | | - "value": "C57BL6J", |
686 | | - "description": "general purpose background strain", |
687 | | - "source": "https://www.jax.org/strain/000664" |
688 | | - }, |
689 | | - { |
690 | | - "value": "APOE4Trem2R47H", |
691 | | - "description": "double mutant with humanized ApoE knock-in mutation and an R47H point mutation of Trem2", |
692 | | - "source": "https://www.jax.org/strain/028709" |
693 | | - }, |
694 | | - { |
695 | | - "value": "Trem2R47H", |
696 | | - "description": "mutant with an R47H point mutation of Trem2", |
697 | | - "source": "https://www.jax.org/strain/027918" |
698 | | - }, |
699 | | - { |
700 | | - "value": "hTauTrem2", |
701 | | - "description": "expresses six isoforms of the human tau protein under the control of the endogenous human MAPT promoter backcrossed into Trem2 −/−mice", |
702 | | - "source": "https://www.synapse.org/#!Synapse:syn18693211" |
703 | | - }, |
704 | | - { |
705 | | - "value": "hAbeta KI", |
706 | | - "description": "triple mutant strain with humanized ApoE knock-in, a mutant App gene, and an R47H point mutation of Trem2", |
707 | | - "source": "https://www.jax.org/strain/030670" |
708 | | - }, |
709 | | - { |
710 | | - "value": "APOE4 KI", |
711 | | - "description": "humanized ApoE knock-in", |
712 | | - "source": "https://www.jax.org/strain/027894" |
713 | 713 | } |
714 | 714 | ] |
715 | 715 | }, |
|
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