diff --git a/src/FlashList.tsx b/src/FlashList.tsx
index 0e9f071a5..e26fb5d3c 100644
--- a/src/FlashList.tsx
+++ b/src/FlashList.tsx
@@ -6,6 +6,7 @@ import {
   NativeSyntheticEvent,
   StyleSheet,
   NativeScrollEvent,
+  Platform,
 } from "react-native";
 import {
   BaseItemAnimator,
@@ -31,10 +32,12 @@ import {
   RenderTargetOptions,
 } from "./FlashListProps";
 import {
+  addInvertedWheelHandler,
   getCellContainerPlatformStyles,
   getFooterContainer,
   getItemAnimator,
   PlatformConfig,
+  removeInvertedWheelHandler,
 } from "./native/config/PlatformHelper";
 import {
   ContentStyleExplicit,
@@ -100,6 +103,8 @@ class FlashList<T> extends React.PureComponent<
   private isEmptyList = false;
   private viewabilityManager: ViewabilityManager<T>;
 
+  private hasInvertedWheelHandler = false;
+
   private itemAnimator?: BaseItemAnimator;
 
   static defaultProps = {
@@ -283,10 +288,27 @@ class FlashList<T> extends React.PureComponent<
     }
   };
 
+  private updateWebScrollHandler() {
+    if (Platform.OS !== "web" || !this.rlvRef) return;
+
+    removeInvertedWheelHandler(this.rlvRef);
+    this.hasInvertedWheelHandler = false;
+
+    if (this.props.inverted) {
+      addInvertedWheelHandler(
+        this.rlvRef,
+        this.props.horizontal ? "horizontal" : "vertical"
+      );
+      this.hasInvertedWheelHandler = true;
+    }
+  }
+
   componentDidMount() {
     if (this.props.data?.length === 0) {
       this.raiseOnLoadEventIfNeeded();
     }
+
+    this.updateWebScrollHandler();
   }
 
   componentWillUnmount() {
@@ -296,6 +318,19 @@ class FlashList<T> extends React.PureComponent<
     if (this.itemSizeWarningTimeoutId !== undefined) {
       clearTimeout(this.itemSizeWarningTimeoutId);
     }
+
+    if (this.hasInvertedWheelHandler) {
+      removeInvertedWheelHandler(this.rlvRef);
+    }
+  }
+
+  componentDidUpdate(prevProps: FlashListProps<T>) {
+    if (
+      prevProps.inverted !== this.props.inverted ||
+      prevProps.horizontal !== this.props.horizontal
+    ) {
+      this.updateWebScrollHandler();
+    }
   }
 
   render() {
@@ -479,9 +514,11 @@ class FlashList<T> extends React.PureComponent<
         >
           {children}
         </AutoLayoutView>
-        {this.isEmptyList
-          ? this.getValidComponent(this.props.ListEmptyComponent)
-          : null}
+        {this.isEmptyList ? (
+          <View style={this.getTransform()}>
+            {this.getValidComponent(this.props.ListEmptyComponent)}
+          </View>
+        ) : null}
         <PureComponentWrapper
           enabled={this.isListLoaded || children.length > 0 || this.isEmptyList}
           contentStyle={this.props.contentContainerStyle}
@@ -642,7 +679,16 @@ class FlashList<T> extends React.PureComponent<
   };
 
   private rowRendererSticky = (index: number) => {
-    return this.rowRendererWithIndex(index, RenderTargetOptions.StickyHeader);
+    return (
+      <View
+        style={{
+          flexDirection: this.props.horizontal ? "row" : "column",
+          ...this.getTransform(),
+        }}
+      >
+        {this.rowRendererWithIndex(index, RenderTargetOptions.StickyHeader)}
+      </View>
+    );
   };
 
   private rowRendererWithIndex = (index: number, target: RenderTarget) => {
diff --git a/src/native/config/PlatformHelper.ts b/src/native/config/PlatformHelper.ts
index b5a46b8e7..65f5d068d 100644
--- a/src/native/config/PlatformHelper.ts
+++ b/src/native/config/PlatformHelper.ts
@@ -1,4 +1,8 @@
-import { BaseItemAnimator } from "recyclerlistview";
+import {
+  BaseItemAnimator,
+  RecyclerListView,
+  RecyclerListViewProps,
+} from "recyclerlistview";
 import { DefaultJSItemAnimator } from "recyclerlistview/dist/reactnative/platform/reactnative/itemanimators/defaultjsanimator/DefaultJSItemAnimator";
 
 const PlatformConfig = {
@@ -21,9 +25,24 @@ const getFooterContainer = (): React.ComponentClass | undefined => {
   return undefined;
 };
 
+const addInvertedWheelHandler = (
+  ref: RecyclerListView<RecyclerListViewProps, any> | undefined,
+  type: "horizontal" | "vertical"
+): (() => void) | undefined => {
+  return undefined;
+};
+
+const removeInvertedWheelHandler = (
+  ref: RecyclerListView<RecyclerListViewProps, any> | undefined
+): (() => void) | undefined => {
+  return undefined;
+};
+
 export {
   PlatformConfig,
   getCellContainerPlatformStyles,
   getItemAnimator,
   getFooterContainer,
+  addInvertedWheelHandler,
+  removeInvertedWheelHandler,
 };
diff --git a/src/native/config/PlatformHelper.web.ts b/src/native/config/PlatformHelper.web.ts
index 950fd0288..e00f9d3d0 100644
--- a/src/native/config/PlatformHelper.web.ts
+++ b/src/native/config/PlatformHelper.web.ts
@@ -1,8 +1,89 @@
 import React from "react";
-import { View } from "react-native";
-import { BaseItemAnimator } from "recyclerlistview";
+import { findNodeHandle, View } from "react-native";
+import {
+  BaseItemAnimator,
+  RecyclerListView,
+  RecyclerListViewProps,
+} from "recyclerlistview";
 import { DefaultJSItemAnimator } from "recyclerlistview/dist/reactnative/platform/reactnative/itemanimators/defaultjsanimator/DefaultJSItemAnimator";
 
+/**
+ * Checks if a wheel event should be handled by a nested scrollable element.
+ */
+const shouldNestedElementHandleScroll = (
+  event: globalThis.WheelEvent
+): boolean => {
+  const targetNode = event.target;
+  if (!(targetNode instanceof HTMLElement)) {
+    return false;
+  }
+
+  let target: HTMLElement | null = targetNode;
+  const currentTarget = event.currentTarget as HTMLElement;
+
+  while (target && target !== currentTarget) {
+    const style = window.getComputedStyle(target);
+    const overflowY = style.overflowY;
+    const overflowX = style.overflowX;
+
+    const isScrollableY =
+      overflowY === "auto" || overflowY === "scroll" || overflowY === "overlay";
+    const isScrollableX =
+      overflowX === "auto" || overflowX === "scroll" || overflowX === "overlay";
+
+    // Check if element should handle vertical scroll
+    if (isScrollableY && target.scrollHeight > target.clientHeight) {
+      if (
+        (event.deltaY > 0 &&
+          target.scrollTop < target.scrollHeight - target.clientHeight) ||
+        (event.deltaY < 0 && target.scrollTop > 0)
+      ) {
+        return true;
+      }
+    }
+
+    // Check if element should handle horizontal scroll
+    if (isScrollableX && target.scrollWidth > target.clientWidth) {
+      if (
+        (event.deltaX > 0 &&
+          target.scrollLeft < target.scrollWidth - target.clientWidth) ||
+        (event.deltaX < 0 && target.scrollLeft > 0)
+      ) {
+        return true;
+      }
+    }
+
+    target = target.parentElement;
+  }
+
+  return false;
+};
+
+const createInvertedWheelEventHandler = (type: "horizontal" | "vertical") => {
+  return (event: globalThis.WheelEvent) => {
+    if (shouldNestedElementHandleScroll(event)) {
+      return;
+    }
+
+    const currentTarget = event.currentTarget as HTMLElement;
+    const deltaX = type === "horizontal" ? -event.deltaX : event.deltaX;
+    const deltaY = type === "vertical" ? -event.deltaY : event.deltaY;
+
+    currentTarget.scrollBy({
+      top: deltaY,
+      left: deltaX,
+      behavior: "auto",
+    });
+
+    event.preventDefault();
+  };
+};
+
+const verticalInvertedWheelEventHandler =
+  createInvertedWheelEventHandler("vertical");
+const horizontalInvertedWheelEventHandler =
+  createInvertedWheelEventHandler("horizontal");
+
 const PlatformConfig = {
   defaultDrawDistance: 2000,
   invertedTransformStyle: { transform: [{ scaleY: -1 }] },
@@ -25,10 +106,41 @@ const getItemAnimator = (): BaseItemAnimator | undefined => {
 const getFooterContainer = (): React.ComponentClass | undefined => {
   return View;
 };
+const addInvertedWheelHandler = (
+  ref: RecyclerListView<RecyclerListViewProps, any> | undefined,
+  type: "horizontal" | "vertical"
+): ((event: globalThis.WheelEvent) => void) | undefined => {
+  if (!ref) return undefined;
+  const node = findNodeHandle(ref) as unknown as HTMLElement;
+  if (node) {
+    const handler =
+      type === "horizontal"
+        ? horizontalInvertedWheelEventHandler
+        : verticalInvertedWheelEventHandler;
+    node.addEventListener("wheel", handler, {
+      passive: false,
+    });
+    return handler;
+  }
+  return undefined;
+};
+const removeInvertedWheelHandler = (
+  ref: RecyclerListView<RecyclerListViewProps, any> | undefined
+): ((event: globalThis.WheelEvent) => void) | undefined => {
+  if (!ref) return undefined;
+  const node = findNodeHandle(ref) as unknown as HTMLElement;
+  if (node) {
+    node.removeEventListener("wheel", verticalInvertedWheelEventHandler);
+    node.removeEventListener("wheel", horizontalInvertedWheelEventHandler);
+  }
+  return undefined;
+};
 
 export {
   PlatformConfig,
   getCellContainerPlatformStyles,
   getItemAnimator,
   getFooterContainer,
+  addInvertedWheelHandler,
+  removeInvertedWheelHandler,
 };