How apply mi-CNN_MSI on data (*.imzML) collected by high mass resolution MALDI-FT-ICR MSI instrument ?

[anani-a-missinou]

Dear Dan Guo,

I’m working on Brassica napus (rapeseed) specialized metabolites against pathogens at Institute for Genetics, Environment, and Plant Protection in France.

We are looking to determine the metabolites that explain the resistance of a variety of rapeseed to blackleg, that causes by L. maculans infection at the stem.

We have :
• imzML files (controls and infected) of susceptible and resistant genotype in three biological replicate.
• Data were collected by FTICR - Imagerie MALDI - FTICR SolariX 7T Paracell combisource ESI/MALDI (Bruker Daltonics).

We want to apply your LIME analysis of mi-SVM on our data in order to select the most predictive features of resistance to blackleg.

Please could you help us to apply it?

I sincerely thank you for your answer. Respectfully yours