Source code for figure generation accompanying the following manuscript:
Matrix Rigidity Governs Switch-Like Oscillatory State Transitions of the Segmentation Clock in Isolated Presomitic Mesoderm Cells
Chun-Yen Sung†, Yuqian Yang†, Usha Kadiyala‡, Owen Blanchard‡, Liam Yourston‡, Derek Walker, Linyuan Li, Shiyu Sun, Zhaoyi Xu, Mariela Lopez Gonzalez, Jianping Fu, Qiong Yang*
† Co-first authors; ‡ Co-second authors; * Corresponding author*
- MATLAB
- Statistics and Machine Learning Toolbox
- Signal Processing Toolbox
Each folder contains .m analysis/plotting scripts and .mat data files for the corresponding figure:
/Figure1. – Pluronic- and Matrigel-coated glass conditions /Figure2 – Oscillation percentage and period vs. substrate rigidity; model fit /Figure3 – Single-cell motility analysis /Figure4 – Traction force measurements /Figure5 – Cell aggregate oscillation analysis
Each folder contains a main script that loads the corresponding .mat data file and generates the figure. Run the main script from within its folder or add it to the MATLAB path.
Qiong Yang — qiongy@umich.edu Yang Lab, University of Michigan https://github.com/YangLab-um