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[DO NOT MERGE] eval #31961 i:2: obsolete GO:0008785 alkyl hydroperoxide reductase activity (openai/gpt-5.4, .)#50

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dragon-ai-agent wants to merge 2 commits intoeval-base-issue-31961from
scribe-v1-ai4curation-go-ontology-agent-config-v9-.-openai-gpt-5.4-iter2-issue-31961
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[DO NOT MERGE] eval #31961 i:2: obsolete GO:0008785 alkyl hydroperoxide reductase activity (openai/gpt-5.4, .)#50
dragon-ai-agent wants to merge 2 commits intoeval-base-issue-31961from
scribe-v1-ai4curation-go-ontology-agent-config-v9-.-openai-gpt-5.4-iter2-issue-31961

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⚠️ EVALUATION ONLY - DO NOT MERGE ⚠️

Original Issue

#31961: obsolete GO:0008785 alkyl hydroperoxide reductase activity

Original PR (human solution)

#32015: Obsolete GO:0008785 alkyl hydroperoxide reductase activity (#31961)

Agent Commits

  • obsolete GO:0008785 as overly specific catalytic activity

Note: This PR diff shows ONLY the agent's changes. The baseline is eval_base_branch.

Agent Response - PR Comments

Obsoleted GO:0008785 alkyl hydroperoxide reductase activity and replaced it with GO:0102039 NADH-dependent peroxiredoxin activity as requested in issue #31961.

Changes made:

  • Converted GO:0008785 to an obsolete term with replaced_by: GO:0102039.
  • Added a new term_tracker_item for issue #31961 and recorded the obsoletion reason on the obsolete term.
  • Updated the GO:0009321 alkyl hydroperoxide reductase complex see-also comment to reference GO:0102039 instead of the obsolete MF term.
  • Removed a stray comment on GO:0070937 CRD-mediated mRNA stability complex that still pointed to GO:0008785.

Rationale:

  • The issue already identified GO:0008785 as an overly substrate-specific activity term with GO:0102039 as the correct replacement.
  • Obsoleting the term without cleaning up remaining internal references would leave stale ontology comments pointing at an obsolete MF term.

Validation:

  • Ran make travis_build in src/ontology.
  • Build completed successfully, including ROBOT verification and obsolete-reference checks.

Checklist:

  • PLAN: Reviewed the imported issue title, body, and comments.
  • PRE-VALIDATION: N/A as a separate baseline run was not performed; post-change full validation passed.
  • RESEARCH: N/A; no new biological assertions or literature-backed definitions were added.
  • TERM-SEARCH: Reviewed GO:0008785, GO:0102039, and all internal GO:0008785 references in go-edit.obo.
  • DESIGN-PATTERNS: N/A; no new terms or logical definitions were added.
  • EDITS: Used obo-checkout.pl and obo-checkin.pl with local files in terms/.
  • RELATIONSHIPS: Removed active axioms from the obsolete term and rewired or removed stale internal references.
  • SPECIALIZED-EDITS: Applied /term-obsoletion guidance; /reaction was consulted because this is a catalytic activity term.
  • METADATA: Preserved existing provenance, added the new issue tracker item, and did not add creation metadata to existing terms.
  • AUTOMATED-VALIDATION: make travis_build passed.
  • REFERENCE-VALIDATION: N/A; no new PMIDs, RHEA IDs, EC IDs, or other reference IDs were introduced.
  • CHANGES-COMMITTED: Local commit created: 10e9bf4 (obsolete GO:0008785 as overly specific catalytic activity).

🤖 Generated by opencode agent

  • Runtime: opencode
  • Model: openai/gpt-5.4
  • Agent config: ai4curation/go-ontology-agent-config@v9:.
  • Iteration: 2
  • Run: View workflow run

Agent Response - Issue Comments

Implemented locally in PR #.

GO:0008785 alkyl hydroperoxide reductase activity has been obsoleted and replaced by GO:0102039 NADH-dependent peroxiredoxin activity, consistent with the issue discussion that the obsolete term was more specific than any supported gene product annotation. I also updated the GO:0009321 see-also comment to point at GO:0102039 and removed one stray obsolete-term comment from GO:0070937.

Validation passed with make travis_build.


🤖 Generated by opencode agent

  • Runtime: opencode
  • Model: openai/gpt-5.4
  • Agent config: ai4curation/go-ontology-agent-config@v9:.
  • Iteration: 2
  • Run: View workflow run

Experiment Config

Parameter Value
Model openai/gpt-5.4
Agent config ai4curation/go-ontology-agent-config@v9:.
Iteration 2
URL prefix https://href.li/?
Base branch eval-base-issue-31961

See workflow artifacts for full agent trace.

@dragon-ai-agent
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📋 Traces: traces/25613564661

github-actions Bot added 2 commits May 9, 2026 23:36
Model: openai/gpt-5.4
Issue repo: geneontology/go-ontology
Agent config: ai4curation/go-ontology-agent-config@v9:.
Iteration: 2

Artifacts: https://github.com/ai4curation/eval-ont-agent-go/actions/runs/25614306977#artifacts
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Superseded by new run (force_new_branch=true)

@github-actions github-actions Bot force-pushed the scribe-v1-ai4curation-go-ontology-agent-config-v9-.-openai-gpt-5.4-iter2-issue-31961 branch from a54d841 to 6a2d88b Compare May 9, 2026 23:36
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