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Error in unite() when specifying destrand = TRUE #349

@BenTPTseng

Description

@BenTPTseng

Hi,

As written in the title, it showed:

[E::hts_idx_push] Chromosome blocks not continuous
Error in value[[3L]](cond) : index build failed

We have double checked that the methylRawListDB object does contain strand information (i.e + and -). We have also traced back the building blocks of unite() function through: destrandFun() -> applyTbxByChunk() -> getTabixByChunk(). We guess that getTabixByChunk() is presumably the origin of error.

Do you have any thoughts on fixing the issues?

Example of our methylRawListDB object
> myobj[[1]] |> head(n=30)
    chr  start    end strand coverage numCs numTs
1  chr1  29268  29268      -       12     0    12
2  chr1  29273  29273      -       12     1    11
3  chr1  29286  29286      -       12     0    12
4  chr1  29299  29299      -       11     0    11
5  chr1  29301  29301      -       11     0    11
6  chr1  29307  29307      -       10     0    10
7  chr1  29311  29311      -       13     1    12
8  chr1  29348  29348      -       14     0    14
9  chr1  29351  29351      -       13     0    13
10 chr1  29354  29354      -       14     0    14
11 chr1  29360  29360      -       12     0    12
12 chr1  29368  29368      -       14     0    14
13 chr1  29374  29374      -       14     2    12
14 chr1  29390  29390      -       13     1    12
15 chr1  29393  29393      -       12     0    12
16 chr1  29404  29404      -       13     0    13
17 chr1  29408  29408      -       13     0    13
18 chr1  29410  29410      -       13     0    13
19 chr1  29416  29416      -       13     0    13
20 chr1 181056 181056      -       16    16     0
21 chr1 181073 181073      -       15    15     0
22 chr1 181094 181094      -       16    16     0
23 chr1 181102 181102      -       14    14     0
24 chr1 181119 181119      +       13    13     0
25 chr1 181139 181139      +       20    20     0
26 chr1 181140 181140      -       15    15     0
27 chr1 181147 181147      +       20    20     0
28 chr1 181148 181148      -       16    16     0
29 chr1 181150 181150      +       20    14     6
30 chr1 181151 181151      -       16    16     0

Thank you!

Regards,
Ben

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