diff --git a/src/anthropic/_base_client.py b/src/anthropic/_base_client.py
index 963cd1b9..5c5c94a8 100644
--- a/src/anthropic/_base_client.py
+++ b/src/anthropic/_base_client.py
@@ -810,6 +810,11 @@ def _should_retry(self, response: httpx.Response) -> bool:
             log.debug("Retrying due to status code %i", response.status_code)
             return True
 
+        # Retry on failed dependency (often transient in Bedrock).
+        if response.status_code == 424:
+            log.debug("Retrying due to status code %i", response.status_code)
+            return True
+
         # Retry on lock timeouts.
         if response.status_code == 409:
             log.debug("Retrying due to status code %i", response.status_code)