diff --git a/sdks/python/apache_beam/runners/direct/direct_runner.py b/sdks/python/apache_beam/runners/direct/direct_runner.py
index 8b8937653688..9d9d75833c89 100644
--- a/sdks/python/apache_beam/runners/direct/direct_runner.py
+++ b/sdks/python/apache_beam/runners/direct/direct_runner.py
@@ -52,6 +52,7 @@
 from apache_beam.transforms.ptransform import PTransform
 from apache_beam.transforms.timeutil import TimeDomain
 from apache_beam.typehints import trivial_inference
+from apache_beam.utils.interactive_utils import is_in_ipython
 
 __all__ = ['BundleBasedDirectRunner', 'DirectRunner', 'SwitchingDirectRunner']
 
@@ -114,7 +115,11 @@ class _PrismRunnerSupportVisitor(PipelineVisitor):
       """Visitor determining if a Pipeline can be run on the PrismRunner."""
       def accept(self, pipeline):
         self.supported_by_prism_runner = True
-        pipeline.visit(self)
+        # TODO(https://github.com/apache/beam/issues/33623): Prism currently does not support interactive mode
+        if is_in_ipython():
+          self.supported_by_prism_runner = False
+        else:
+          pipeline.visit(self)
         return self.supported_by_prism_runner
 
       def visit_transform(self, applied_ptransform):
@@ -136,40 +141,32 @@ def visit_transform(self, applied_ptransform):
           if userstate.is_stateful_dofn(dofn):
             # https://github.com/apache/beam/issues/32786 -
             # Remove once Real time clock is used.
-            _, timer_specs = userstate.get_dofn_specs(dofn)
+            state_specs, timer_specs = userstate.get_dofn_specs(dofn)
             for timer in timer_specs:
               if timer.time_domain == TimeDomain.REAL_TIME:
                 self.supported_by_prism_runner = False
 
-    tryingPrism = False
+            for state in state_specs:
+              if isinstance(state, userstate.CombiningValueStateSpec):
+                self.supported_by_prism_runner = False
+
+    # Use BundleBasedDirectRunner if other runners are missing needed features.
+    runner = BundleBasedDirectRunner()
+
     # Check whether all transforms used in the pipeline are supported by the
-    # FnApiRunner, and the pipeline was not meant to be run as streaming.
-    if _FnApiRunnerSupportVisitor().accept(pipeline):
-      from apache_beam.portability.api import beam_provision_api_pb2
-      from apache_beam.runners.portability.fn_api_runner import fn_runner
-      from apache_beam.runners.portability.portable_runner import JobServiceHandle
-      all_options = options.get_all_options()
-      encoded_options = JobServiceHandle.encode_pipeline_options(all_options)
-      provision_info = fn_runner.ExtendedProvisionInfo(
-          beam_provision_api_pb2.ProvisionInfo(
-              pipeline_options=encoded_options))
-      runner = fn_runner.FnApiRunner(provision_info=provision_info)
-    elif _PrismRunnerSupportVisitor().accept(pipeline):
+    # PrismRunner
+    if _PrismRunnerSupportVisitor().accept(pipeline):
       _LOGGER.info('Running pipeline with PrismRunner.')
       from apache_beam.runners.portability import prism_runner
       runner = prism_runner.PrismRunner()
-      tryingPrism = True
-    else:
-      runner = BundleBasedDirectRunner()
 
-    if tryingPrism:
       try:
         pr = runner.run_pipeline(pipeline, options)
         # This is non-blocking, so if the state is *already* finished, something
         # probably failed on job submission.
         if pr.state.is_terminal() and pr.state != PipelineState.DONE:
           _LOGGER.info(
-              'Pipeline failed on PrismRunner, falling back toDirectRunner.')
+              'Pipeline failed on PrismRunner, falling back to DirectRunner.')
           runner = BundleBasedDirectRunner()
         else:
           return pr
@@ -181,6 +178,19 @@ def visit_transform(self, applied_ptransform):
         _LOGGER.info('Falling back to DirectRunner')
         runner = BundleBasedDirectRunner()
 
+    # Check whether all transforms used in the pipeline are supported by the
+    # FnApiRunner, and the pipeline was not meant to be run as streaming.
+    if _FnApiRunnerSupportVisitor().accept(pipeline):
+      from apache_beam.portability.api import beam_provision_api_pb2
+      from apache_beam.runners.portability.fn_api_runner import fn_runner
+      from apache_beam.runners.portability.portable_runner import JobServiceHandle
+      all_options = options.get_all_options()
+      encoded_options = JobServiceHandle.encode_pipeline_options(all_options)
+      provision_info = fn_runner.ExtendedProvisionInfo(
+          beam_provision_api_pb2.ProvisionInfo(
+              pipeline_options=encoded_options))
+      runner = fn_runner.FnApiRunner(provision_info=provision_info)
+
     return runner.run_pipeline(pipeline, options)
 
 
diff --git a/sdks/python/apache_beam/runners/direct/direct_runner_test.py b/sdks/python/apache_beam/runners/direct/direct_runner_test.py
index 1af5f1bc7bea..a14eba851c48 100644
--- a/sdks/python/apache_beam/runners/direct/direct_runner_test.py
+++ b/sdks/python/apache_beam/runners/direct/direct_runner_test.py
@@ -47,9 +47,10 @@ class DirectPipelineResultTest(unittest.TestCase):
   def test_waiting_on_result_stops_executor_threads(self):
     pre_test_threads = set(t.ident for t in threading.enumerate())
 
-    for runner in ['DirectRunner',
-                   'BundleBasedDirectRunner',
-                   'SwitchingDirectRunner']:
+    for runner in [
+        'BundleBasedDirectRunner',
+        'apache_beam.runners.portability.fn_api_runner.fn_runner.FnApiRunner'
+    ]:
       pipeline = test_pipeline.TestPipeline(runner=runner)
       _ = (pipeline | beam.Create([{'foo': 'bar'}]))
       result = pipeline.run()