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Efficient Fault Detection and Diagnosis of DigitalMicrofluidic Biochip Using Multiple ElectrodesActuation

Abstract

Nowadays, Digital Microfluidic biochip (DMFB) is apromising platform where we can concurrently execute complexbioassay operations. This automated, integrated chip is usedin Many safety-critical applications like air-quality monitoring,point-of-care health assessment, automated drug discovery, par-allel DNA analysis and this is possible only by deploying arobust testing mechanism. Some of the earlier reported testingand diagnosis algorithms are mostly concentrated on single faultlocalization or take a significant amount of time for multiplefaults detection. Even in some cases, a non-faulty electrodeincorrectly classified as a faulty electrode. Thus in this work, wehave proposed a multiple electrodes actuation method for correctlocalization of the defective electrode(s) within very less time.Moreover, when some other bioassay operations are running ina biochip then also our proposed method can diagnose the faultsof the biochip.