cluster_ref Static Reference Data h5ad H5AD File align Gene Align h5ad->align stream embed_model scFM align->embed_model embeddings Embeddings embed_model->embeddings umap_model PUMAP coords 2D Coordinates umap_model->coords embeddings->umap_model ivf IVF embeddings->ivf viz Visualization coords->viz ann ANN Search ivf->ann pq PQ pq->ann neighbors Nearest Neighbor Labels ann->neighbors neighbors->viz ref_embeddings 20M+ Embeddings ref_embeddings->pq ref_labels Annotations ref_labels->neighbors ref_centroids Centroids ref_centroids->ivf ref_codebooks Codebooks ref_codebooks->pq