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Scale down GQ in CombineBatches (#796)
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wdl/CleanVcfChromosome.wdl

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@@ -323,7 +323,6 @@ workflow CleanVcfChromosome {
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input:
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vcf=FinalCleanup.final_cleaned_shard,
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ploidy_table=ploidy_table,
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args="--scale-down-gq",
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output_prefix="~{prefix}.final_format",
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script=svtk_to_gatk_script,
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sv_pipeline_docker=sv_pipeline_docker,

wdl/CombineBatches.wdl

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@@ -112,7 +112,7 @@ workflow CombineBatches {
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input:
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vcf=reformatted_vcf,
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ploidy_table=CreatePloidyTableFromPed.out,
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args="--fix-end --add-sr-pos",
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args="--fix-end --add-sr-pos --scale-down-gq",
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output_prefix=basename(vcf, ".vcf.gz") + ".reformat_gatk",
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bothside_pass_list=CombineSRBothsidePass.out,
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background_fail_list=CombineBackgroundFail.outfile,

wdl/MainVcfQc.wdl

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@@ -26,7 +26,7 @@ workflow MainVcfQc {
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Array[Array[String]]? sample_level_comparison_datasets # Array of two-element arrays, one per dataset, each of format [prefix, gs:// path to per-sample tarballs]
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File primary_contigs_fai
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Int? random_seed
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Int? max_gq # Max GQ for plotting. Default = 99, ie. GQ is on a scale of [0,99]. Prior to CleanVcf, use 999
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Int? max_gq # Max GQ for plotting. Default = 99, ie. GQ is on a scale of [0,99]. Prior to CombineBatches, use 999
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Int? downsample_qc_per_sample # Number of samples to use for per-sample QC. Default: 1000
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String sv_base_mini_docker

wdl/MakeCohortVcf.wdl

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@@ -71,7 +71,7 @@ workflow MakeCohortVcf {
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File? outlier_samples_list
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Int? random_seed
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Int? max_gq # Max GQ for plotting. Default = 99, ie. GQ is on a scale of [0,99]. Prior to CleanVcf, use 999
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Int? max_gq # Max GQ for plotting. Default = 99, ie. GQ is on a scale of [0,99]. Prior to CombineBatches, use 999
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Array[Array[String]]? site_level_comparison_datasets # Array of two-element arrays, one per dataset, each of format [prefix, gs:// path to directory with one BED per population]
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Array[Array[String]]? sample_level_comparison_datasets # Array of two-element arrays, one per dataset, each of format [prefix, gs:// path to per-sample tarballs]

website/docs/modules/main_vcf_qc.md

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@@ -214,7 +214,7 @@ section for available benchmarking call sets.
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Default: `0`. Random seed for sample subsetting in external call set comparisons.
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#### <HighlightOptionalArg>Optional</HighlightOptionalArg> `max_gq`
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Default: `99`. Max value to define range for `GQ` plotting. For modules prior to `CleanVcf`, use `999`.
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Default: `99`. Max value to define range for `GQ` plotting. For modules prior to `CombineBatches`, use `999`.
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#### <HighlightOptionalArg>Optional</HighlightOptionalArg> `downsample_qc_per_sample`
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Default: `1000`. Number of samples to subset to for per-sample QC.

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