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Variants in the browser (and all current VCFs available for download) were annotated using Ensembl VEP version 105 using GENCODE v39 on GRCh38, with the [LOFTEE](https://github.com/konradjk/loftee) (Loss-Of-Function Transcript Effect Estimator) plugin.
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Note that variants in the gene [RNU4ATAC](https://gnomad.broadinstitute.org/gene/ENSG00000264229?dataset=gnomad_r4) were annotated using Ensembl VEP version 115 (GENCODE v49) on GRCh38. Ensembl VEP version 115 annotations for other genes are available in our [downloadable files](https://gnomad.broadinstitute.org/data#v4). We are not currently planning to update the Ensembl VEP version for other genes in the gnomAD browser.
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Note that variants in the gene [RNU4ATAC](https://gnomad.broadinstitute.org/gene/ENSG00000264229?dataset=gnomad_r4) were annotated using Ensembl VEP version 115 (GENCODE v49) on GRCh38. Ensembl VEP version 115 annotations for other [GENCODE basic transcripts](https://www.gencodegenes.org/pages/faq.html)are available in our [downloadable Hail Tables](https://gnomad.broadinstitute.org/data#v4). We are not currently planning to update the Ensembl VEP version for other genes in the gnomAD browser.
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