COPASI 4.26 (Build 213)

The COPASI team announces the immediate availability of the stable release COPASI 4.26 (Build 213).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This release has several new features:

• Graphical User Interface (CopasiUI)
  • Added feature to open files directly from a web page which use the link format: 'copasi://'.
  • It is to possible to specify a user selected list of time point for output in the trajectory tasks.
  • It is now possible to enable automated checks for updates of COPASI as you are used to in many other applications.
  • We added a tool to remove SBML Ids from the COPASI file which are used to facilitate referencing the original SBML Id on export. When an object was renamed the original SBML Id is preserved which is desired in most cases. However there are circumstances where this behavior is not desired. Removing the SBML Ids leads to newly created Id based on the names in COPASI.
  • A COPASI file downloaded using the 'Open URL' method has the targets of reports removed so that a malicious user cannot automatically create harmful content.
• Command-line (CopasiSE)
  • Added option to export ant import different parameterizations of the model through simple ini file.

Release Date: July 31, 2019

More information can be found in the changelog.

COPASI 4.25 (Build 207)

The COPASI team announces the immediate availability of the stable release COPASI 4.25 (Build 207).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This release has several new features:

• Graphical User Interface (CopasiUI)
  • Added capability to load and save model parameter sets from files.
  • Moiety results are now displayed according to the framework, i.e. in amount units or particle numbers.
  • Added default report moiety task
  • Advanced rarely used method parameters are no hidden if they are at default setting. The user can change this behavior through the preference dialog.
  • Combine archive are can now be opened via drag and drop like all other supported formats.
  • Added additional plot type supporting banded graphs.
  • Added the capability to open files directly from an URL under the file menu.
  • Added Lyapunov exponents to the selectable result in the object selection widget.
• Command-line (CopasiSE)
  • Added option to convert the model reactions to irreversible
  • Added option to specify the task to be executed
  • Added option to override the report file name to be used.
• Language Bindings
  • The sed-ml and combine archive functionalities are now exposed in the language bindings.

Release Date: March 15, 2019

More information can be found in the changelog.

COPASI 4.24 (Build 197)

The COPASI team announces the immediate availability of the stable release COPASI 4.24 (Build 197).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This is mainly a bug fix release with some GUI improvements:

• Graphical User Interface
  • Implemented a new 3d bar graph view of matrixes allowing for better selection of interesting values. The new view also avoids OpenGL issues due to incomplete graphic card support of the OS.
  • Improved issue display in the object browser which did not recognize missing expressions for entities of type ODE and occasionally marked missing initial expressions when not required.
  • Improved display of advanced method parameters. If advanced parameter usage is indicated in the preferences they will be shown last. If it is not selected non advanced parameters which are not at their value will be shown to inform the user.
• SBML
  • Models which explicitely reference Avogadro's number can now be exported to SBML.

Release Date: July 30, 2018

More information can be found in the changelog.

COPASI 4.23 (Build 184)

The COPASI team announces the immediate availability of the stable release COPASI 4.23 (Build 184).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the
Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This release includes many new features:

New Features

• Graphical User Interface
  • Model Merging: COPASI allows to add a second model and to merge its content with the existing one.
  • Compartment dimensionality may now be specified as: volume, area, length, or dimensionless.
  • Problems (Errors, Warnings) of the model are no marked in the object browser at the problematic entity.
  • Enhanced Unit Support for kinetic parameters.
  • Import and export of Combine Archive is now supported.
  • The full and reduced Jacobian of the current model state are now shown under Model/Mathematical/Matrices.
  • Enable copying table and annotated matrix items to the clipboard.
  • A warning is now raised when loading an invalid model (i.e: one that does not compile) and the problematic
    entity is marked in the browser pane.
  • Added ability to add COPASI version, current date/time, first name, last name, email and organization as
    well as line breaks to a reports.
  • Allow for the selection of matrices in Object Browser expert mode.
  • Plots can be associated with tasks similar to the existing report association
  • The direct dependencies, i.e, the objects which are directly effected by changes or removal of an
    entity are now displayed on all modeling entities.
• Simulation Engine
  • COPASI supports Stochastic Differential Equations (SDEs). It is possible to add noise to reactions and
    entities (compartments, species, and global quantities) determined by ODEs.
    Release Date: April 18, 2018

More information can be found in the changelog.

COPASI 4.22 (Build 170)

The COPASI team announces the immediate availability of the stable release COPASI 4.22 (Build 170).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the
Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. The main improvement in this release is the significantly increased performance.

Release Date: November 10, 2017

More information can be found in the changelog.

COPASI 4.21 (Build 166)

The COPASI team announces the immediate availability of the stable release COPASI 4.21 (Build 166).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the
Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. The main improvement in this release is the significantly increased performance.

Release Date: October 09, 2017

More information can be found in the changelog.

COPASI 4.20 (Build 158)

The COPASI team announces the immediate availability of the stable release COPASI 4.20 (Build 158).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This is mainly a bug fix release and with the following new features:

• Graphical User Interface (CopasiUI)
  • It is now possible to export the rendered mathematical expressions to a PDF document.
  • The application window remembers the size of the window and the with of the left browser pane to avoid frequent adjustment by the user.
  • Plots can now be activated and deactivated in the plot itself.
  • When an experimental data file is not found at the expected location COPASI allows now specify a new location by opening a file open dialog.
• Simulation Engine
  • The Avogadro symbol can now be used in user defined functions.

Release Date: July 31, 2017

More information can be found in the changelog.

COPASI 4.19 (Build 140) Released

The COPASI team announces the immediate availability of the stable release COPASI 4.19 (Build 140).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This is a bug fix release which fixes an access violation crash.

Release Date: January 12, 2017

More information can be found in the changelog.

COPASI 4.18 (Build 136) Released

The COPASI team announces the immediate availability of the stable release COPASI 4.18 (Build 136).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This is a bug fix release which fixes an access violation crash.

Release Date: November 28, 2016

More information can be found in the changelog.

COPASI 4.17 (Build 135) Released

The COPASI team announces the immediate availability of the stable
release COPASI 4.17 (Build 135).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge.

Release Date: November 21, 2016

New Features since COPASI 4.16 (Build 104)

• Graphical User Interface (CopasiUI)
  • Support for user defined units.
  • Extended unit selection options for time, volume and quantity of the model. These extended options include user defined units.
  • Unit support for Global Quantities.
  • Undo and redo support for all model changes.
  • Improved user interface to method parameters.
  • Selection of matrix and vector elements by name in addition to the index for plots, reports, and in mathematical expressions.
  • Support for contour plots.
  • Sorting off all analysis result tables is now enabled where appropriate.
  • The MCA results contain now information whether the summation theorems are violated or not allowing the user to easily evaluate the numerical accuracy of the result.
  • It is now possible to the select the units of the rate low for a reaction as either amount per time or concentration per time. If concentration per time is selected and the reaction participates in multiple compartments the scaling compartment can be selected.
• Simulation Engine
  • Added support for arbitrary events to the Stochastic Direct Method.
  • New hybrid simulation algorithm: (Hybrid RK-45) which supports arbitrary discrete events and user defined ODEs. Additionally, the user can specify which reaction are treated continuously and which are treated discretely. This algorithm passes the SBML semantic test suite and stochastic suite.
  • It is now possible to report or plot only the internal steps taken by the integration algorithm in the trajectory task.
• SBML
  • Full support for SBML Level 3.1 event semantics
  • Import and export of unit definitions.
  • SBOTerms are no imported and displayed as part of the MIRIAM annotation. On export a the first SBOTerm of the MIRIAM annotation is used if the SBML entity does not have the SBOTerm set.

A list of resolved issues can be found in the
[changelog]({{ site.baseurl }}/Support/Change_History/COPASI_4_17_Build_135/).