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Updated example data
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exampledata/normal.bam

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exampledata/normal.bam.REMOVED.git-id

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exampledata/s2.raw.vcf

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##source=strelka
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##source_version=2.8.3
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##startTime=Tue Oct 31 14:10:58 2017
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##cmdline=/illumina/pipeline/strelka/2.8.3/bin/configureStrelkaSomaticWorkflow.py --indelCandidates manta/results/variants/candidateSmallIndels.vcf.gz --normalBam /illumina/runs/yan_working_dir/genome_in_a_bottle/genome_in_a_bottle/merged_sorted_markdups/24385-200_AH5G7WCCXX_S4_L004_aligned.sorted.mark_dups.bam --tumorBam /illumina/runs/yan_working_dir/genome_in_a_bottle/genome_in_a_bottle/merged_sorted_markdups/24385-12878-30-200_aligned.sorted.mark_dups.bam --referenceFasta /illumina/genomes/Homo_sapiens/Ensembl/GRCh37_Release75/Sequence/WholeGenomeFasta/genome.fa --runDir strelka2
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##cmdline=/illumina/pipeline/strelka/2.8.3/bin/configureStrelkaSomaticWorkflow.py --indelCandidates manta/results/variants/candidateSmallIndels.vcf.gz --normalBam /illumina/runs/chris_working_dir/genome_in_a_bottle/genome_in_a_bottle/merged_sorted_markdups/24385-200_AH5G7WCCXX_S4_L004_aligned.sorted.mark_dups.bam --tumorBam /illumina/runs/chris_working_dir/genome_in_a_bottle/genome_in_a_bottle/merged_sorted_markdups/24385-12878-30-200_aligned.sorted.mark_dups.bam --referenceFasta /illumina/genomes/Homo_sapiens/Ensembl/GRCh37_Release75/Sequence/WholeGenomeFasta/genome.fa --runDir strelka2
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##reference=file:///illumina/genomes/Homo_sapiens/Ensembl/GRCh37_Release75/Sequence/WholeGenomeFasta/genome.fa
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##contig=<ID=1,length=249250621>
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##contig=<ID=2,length=243199373>

exampledata/test.sh

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#!/bin/bash
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## Examples of how to run FiNGS on the example data, with number of PASSing variants for each
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python3 ../FiNGS.py -n normal.bam -t tumor.bam -v s2.raw.vcf --PASSonlyin --PASSonlyout --overwrite # 16 PASS
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## Recommended settings
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python3 ../FiNGS.py -n normal.bam -t tumor.bam -v s2.raw.vcf --PASSonlyin --PASSonlyout # 16 PASS
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## ICGC mode
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#python3 ../FiNGS.py -n normal.bam -t tumor.bam -v s2.raw.vcf -r /path/to/reference/genome.fa --PASSonlyin --PASSonlyout --ICGC # 23 PASS
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## Other options
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#python3 ../FiNGS.py -n normal.bam -t tumor.bam -v s2.raw.vcf --PASSonlyin # 16 PASS, 38 total
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#python3 ../FiNGS.py -n normal.bam -t tumor.bam -v s2.raw.vcf --PASSonlyout # 20 PASS
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#python3 ../FiNGS.py -n normal.bam -t tumor.bam -v s2.raw.vcf # 20 PASS, 1207 total
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## ICGC mode
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#python3 ../FiNGS.py -n normal.bam -t tumor.bam -v s2.raw.vcf -r /path/to/reference/genome.fa --PASSonlyin --PASSonlyout --ICGC # 23 PASS
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exampledata/tumor.bam

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exampledata/tumor.bam.REMOVED.git-id

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functions/filter_functions.py

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import statsmodels.nonparametric.api as smnp
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import matplotlib.backends.backend_pdf
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#matplotlib.use('Agg') # Allows plotting without X-server; must be done before importing matplotlib.pyplot
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from matplotlib import pyplot
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from collections import OrderedDict
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from itertools import repeat, product
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def filterplotter(tdata,ndata,fdata,pdict,sdict,resultsdir):
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## Read in tdata and ndata
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try:
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#tdf = pandas.read_csv(tdata, compression='gzip', sep="\t", header=None, names=cnames)
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#ndf = pandas.read_csv(ndata, compression='gzip', sep="\t", header=None, names=cnames)
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tdf = pandas.read_csv(tdata, compression='gzip', sep="\t", header=0)
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ndf = pandas.read_csv(ndata, compression='gzip', sep="\t", header=0)
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