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Compositional_data_microbiome_statistics

CODA

Scripts and concepts for statistical analysis of microbiome data. Important to note that microbiome data is compositional in nature.

  1. Normalisation methods-

CLR (Centred Log Ratio)- available tools and packages

Deal with zero count values in sparse data-

  • zcompositions R package
  • ALDEX2 (Bioconductor)- includes clr and it deals with compositional data using log-ratio transformation