diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index f916409f..333ac6ad 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -21,3 +21,31 @@ jobs:
     with:
       license-check: true
       lint: true
+  bun:
+    runs-on: ubuntu-latest
+    continue-on-error: true
+    steps:
+      - uses: actions/checkout@v4
+        with:
+          persist-credentials: false
+
+      - name: Setup Bun
+        uses: oven-sh/setup-bun@v2
+
+      - name: Install dependencies
+        # The erraneous typod version `5.0.0-aplha` takes priority over .3 as 'p' > 'l'
+        run: |
+          bun i --ignore-scripts
+          bun i -D --ignore-scripts fastify@5.0.0-alpha.4
+
+      - name: Run types check
+        run: bun run typescript
+
+      - name: Run Jest tests
+        run: bun run typescript:jest
+
+      - name: Run Vitest tests
+        run: bun run typescript:vitest
+
+      - name: Run unit tests
+        run: bun run unit:bun
diff --git a/lib/find-plugins.js b/lib/find-plugins.js
index 631d8705..5180adeb 100644
--- a/lib/find-plugins.js
+++ b/lib/find-plugins.js
@@ -145,7 +145,10 @@ function accumulatePlugin ({ file, type, opts, pluginTree, prefix }) {
 
 function handleTypeScriptSupport (file, language, isHook = false) {
   if (language === 'typescript' && !runtime.supportTypeScript) {
-    throw new Error(`@fastify/autoload cannot import ${isHook ? 'hooks ' : ''}plugin at '${file}'. To fix this error compile TypeScript to JavaScript or use 'ts-node' to run your app.`)
+    throw new Error(
+      `@fastify/autoload cannot import ${isHook ? 'hooks ' : ''}plugin at '${file}'. ` +
+      'To fix this error transpile TypeScript to JavaScript or use an alternative loader/runtime to run your app.'
+    )
   }
 }
 
diff --git a/lib/runtime.js b/lib/runtime.js
index ed3623f2..eacf8a2d 100644
--- a/lib/runtime.js
+++ b/lib/runtime.js
@@ -33,6 +33,14 @@ function checkEnvVariable (name, value) {
     : process.env[name] !== undefined
 }
 
+function isBun () {
+  return 'Bun' in globalThis
+}
+
+function isDeno () {
+  return 'Deno' in globalThis
+}
+
 const runtime = {}
 // use Object.defineProperties to provide lazy load
 Object.defineProperties(runtime, {
@@ -102,6 +110,8 @@ Object.defineProperties(runtime, {
     get () {
       cache.supportTypeScript ??= (
         checkEnvVariable('FASTIFY_AUTOLOAD_TYPESCRIPT') ||
+        isBun() ||
+        isDeno() ||
         runtime.tsNode ||
         runtime.vitest ||
         runtime.babelNode ||
diff --git a/package.json b/package.json
index 59a8c14d..70e9d67b 100644
--- a/package.json
+++ b/package.json
@@ -19,6 +19,7 @@
     "typescript:vitest": "vitest run",
     "typescript:vitest:dev": "vitest",
     "unit": "node scripts/unit.js",
+    "unit:bun": "node scripts/unit.js bun",
     "unit:with-modules": "tap plugin rm @tapjs/typescript && tap plugin list && tap build && tap test/issues/*/test.js test/commonjs/*.js test/module/*.js"
   },
   "repository": {
diff --git a/scripts/unit.js b/scripts/unit.js
index dd9f74c5..d8bb9ebc 100644
--- a/scripts/unit.js
+++ b/scripts/unit.js
@@ -1,8 +1,9 @@
 'use strict'
 
 const { exec } = require('node:child_process')
+const { argv } = require('node:process')
 
-const child = exec('npm run unit:with-modules')
+const child = exec((argv[2] ?? 'npm') + ' run unit:with-modules')
 
 child.stdout.pipe(process.stdout)
 child.stderr.pipe(process.stderr)