After discussion with @ahwagner about the need for a ClinicalSignificanceProposition
to represent the top-level statement type for all AMP/AASCO Tier statements in the somatic domain, we determined that all the supporting evidence statement types Prognostic
, Diagnostic
and Therapeutic Response
should consistently represent the SPO portion of the SPOQ statement in a consistent manner. Since the Condition
is the correct consistent object
for all 3 statements and the overarching ClinicalSignificance
statement we then need to modify the TherapeuticResponseProposition
to swap objectTherapeutic
with conditionQualifier
.
The result will simply make the TherapeuticResponseProposition
have objectCondition
and therapeuticQualifier
. All other aspects and definitions will remain the same.