v0.8.0 - complete Rust refactor

[imaurer]

BioMCP v0.8.0 is a complete rewrite from Python to Rust. It ships as a single binary — no Python, no pip, no virtual environments. One curl command to install, one binary that does everything: CLI queries, MCP server, HTTP proxy, built-in skills, self-update. It covers 12 biomedical entities across 15+ public data sources including PubMed, ClinicalTrials.gov, ClinVar, gnomAD, UniProt, OpenFDA, OncoKB, and more.

The design philosophy is "one grammar, progressive disclosure." Every entity follows the same search / get / helper pattern, so once you learn how to query genes you already know how to query drugs, variants, trials, and everything else. Sections let you start with a summary card and drill into exactly what you need — pathways, interactions, clinical significance — without getting buried in noise. There are also 14 built-in investigation skills that guide an LLM through multi-step workflows like variant-to-treatment, drug safety review, or rare disease workup.

It works standalone from the command line or as an MCP server for Claude Desktop, Cursor, Claude Code, or any MCP-compatible client. For teams running multiple concurrent workers, there's a shared HTTP mode so all workers share a single rate-limit budget against upstream APIs. The whole thing is MIT licensed and available at biomcp.org.