diff --git a/bin/save-ebuild-env.sh b/bin/save-ebuild-env.sh
index 3a2560aabf..e941017c31 100644
--- a/bin/save-ebuild-env.sh
+++ b/bin/save-ebuild-env.sh
@@ -24,6 +24,16 @@ __save_ebuild_env() {
 				unset PYTHONPATH
 			fi
 		fi
+
+		# These variables contains build host specific configuration. We
+		# want binpkgs generated on different sized hosts to be
+		# identical, so strip them from the binpkg. It's also not needed
+		# for installing / removing a package.
+		unset MAKEOPTS NINJAOPTS
+
+		# These variables are constantly changing. Strip them so we
+		# don't introduce non-reproducible data into the binpkg.
+		unset EPOCHREALTIME EPOCHSECONDS SRANDOM
 	fi
 
 	# misc variables inherited from the calling environment
diff --git a/lib/portage/package/ebuild/_config/special_env_vars.py b/lib/portage/package/ebuild/_config/special_env_vars.py
index 1a66192c96..8a234007a4 100644
--- a/lib/portage/package/ebuild/_config/special_env_vars.py
+++ b/lib/portage/package/ebuild/_config/special_env_vars.py
@@ -112,7 +112,9 @@
         "FEATURES",
         "FILESDIR",
         "HOME",
+        "MAKEOPTS",
         "MERGE_TYPE",
+        "NINJAOPTS",
         "NOCOLOR",
         "NO_COLOR",
         "P",