error message "can't set using a multi-index" when running example data

[jp3117]

hi,

we just installed deTin recently. Python3.7 was required. We also installed all packages. When we tried to run the example data with the command recommended:

python3.7 deTiN/deTiN.py --mutation_data_path example_data/HCC_10_90.call_stats.pon_removed.txt --cn_data_path example_data/HCC-1143_100_T-sim-final.acs.seg --tumor_het_data example_data/HCC_10_90.tumor.hets.tsv --normal_het_data example_data/HCC_10_90.normal.hets.tsv --exac_data_path example_data/exac.pickle_high_af --output_name 10_percent_TiN_simulation --indel_data_path example_data/MuTect2.call_stats.txt --indel_data_type MuTect2 --output_dir example_data/

We got the error message as:

joint TiN estimate = 0.08
Traceback (most recent call last):
File "deTiN/deTiN.py", line 611, in
main()
File "deTiN/deTiN.py", line 572, in main
do.reclassify_mutations()
File "deTiN/deTiN.py", line 387, in reclassify_mutations
self.SSNVs.loc[:, ('p_somatic_given_TiN')] = np.nan_to_num(np.true_divide(numerator, denominator))
File "/usr/local/lib/python3.7/site-packages/pandas/core/indexing.py", line 670, in setitem
iloc._setitem_with_indexer(indexer, value)
File "/usr/local/lib/python3.7/site-packages/pandas/core/indexing.py", line 1601, in _setitem_with_indexer
self._setitem_with_indexer(new_indexer, value)
File "/usr/local/lib/python3.7/site-packages/pandas/core/indexing.py", line 1667, in _setitem_with_indexer
"cannot set using a multi-index "
ValueError: cannot set using a multi-index selection indexer with a different length than the value

Thank you very much for your help.

[npatel-ah]

Downgrading pandas to 1.0.0 and matplotlib to 3.1.3 resolved the same error.
Hope that helps.

[jp3117]

Thank you very much for your help. it works now.