diff --git a/charts/k8s-monitoring/charts/feature-integrations/README.md b/charts/k8s-monitoring/charts/feature-integrations/README.md
index 98908a6f3d..8137ca117e 100644
--- a/charts/k8s-monitoring/charts/feature-integrations/README.md
+++ b/charts/k8s-monitoring/charts/feature-integrations/README.md
@@ -114,6 +114,12 @@ Be sure perform actual integration testing in a live environment in the main [k8
 |-----|------|---------|-------------|
 | grafana | object | `{"instances":[]}` | Scrape metrics/logs from Grafana |
 
+### Integration: Istio
+
+| Key | Type | Default | Description |
+|-----|------|---------|-------------|
+| istio | object | `{"instances":[]}` | Scrape metrics/logs from Istio sidecar and service. |
+
 ### Integration: Loki
 
 | Key | Type | Default | Description |
diff --git a/charts/k8s-monitoring/charts/feature-integrations/default-allow-lists/istio.yaml b/charts/k8s-monitoring/charts/feature-integrations/default-allow-lists/istio.yaml
new file mode 100644
index 0000000000..fcc8072309
--- /dev/null
+++ b/charts/k8s-monitoring/charts/feature-integrations/default-allow-lists/istio.yaml
@@ -0,0 +1,43 @@
+---
+# The set of metrics from Istio required for the Istio integration
+- envoy_cluster_upstream_cx_rx_bytes_total
+- envoy_cluster_upstream_cx_tx_bytes_total
+- galley_validation_failed
+- galley_validation_passed
+- go_memstats_heap_alloc_bytes
+- go_memstats_heap_inuse_bytes
+- go_memstats_heap_sys_bytes
+- istio_agent_go_memstats_heap_alloc_bytes
+- istio_agent_go_memstats_heap_inuse_bytes
+- istio_agent_go_memstats_heap_sys_bytes
+- istio_agent_process_cpu_seconds_total
+- istio_agent_process_open_fds
+- istio_agent_process_resident_memory_bytes
+- istio_agent_process_virtual_memory_bytes
+- istio_build
+- istio_request_bytes_sum
+- istio_request_duration_milliseconds_count
+- istio_request_duration_milliseconds_sum
+- istio_requests_total
+- istio_response_bytes_sum
+- istio_tcp_received_bytes_total
+- istio_tcp_sent_bytes_total
+- istiod_uptime_seconds
+- pilot_conflict_inbound_listener
+- pilot_conflict_outbound_listener_tcp_over_current_tcp
+- pilot_info
+- pilot_k8s_cfg_events
+- pilot_total_xds_internal_errors
+- pilot_total_xds_rejects
+- pilot_xds_cds_reject
+- pilot_xds_eds_reject
+- pilot_xds_lds_reject
+- pilot_xds_pushes
+- pilot_xds_rds_reject
+- pilot_xds_write_timeout
+- process_cpu_seconds_total
+- process_open_fds
+- process_resident_memory_bytes
+- process_virtual_memory_bytes
+- sidecar_injection_failure_total
+- sidecar_injection_success_total
diff --git a/charts/k8s-monitoring/charts/feature-integrations/docs/integrations/istio.md b/charts/k8s-monitoring/charts/feature-integrations/docs/integrations/istio.md
new file mode 100644
index 0000000000..53e7659e02
--- /dev/null
+++ b/charts/k8s-monitoring/charts/feature-integrations/docs/integrations/istio.md
@@ -0,0 +1,62 @@
+# istio
+
+## Values
+
+### Istiod Metrics Settings
+
+| Key | Type | Default | Description |
+|-----|------|---------|-------------|
+| istiodMetrics.enabled | bool | `true` | Whether to enable metrics collection from Istio . |
+| istiodMetrics.extraMetricProcessingRules | string | `""` | Rule blocks to be added to the prometheus.relabel component for MySQL metrics. These relabeling rules are applied post-scrape against the metrics returned from the scraped target, no `__meta*` labels are present. ([docs](https://grafana.com/docs/alloy/latest/reference/components/prometheus/prometheus.relabel/#rule-block)) |
+| istiodMetrics.maxCacheSize | string | `100000` | Sets the max_cache_size for prometheus.relabel component. This should be at least 2x-5x your largest scrape target or samples appended rate. ([docs](https://grafana.com/docs/alloy/latest/reference/components/prometheus.relabel/#arguments)) Overrides global.maxCacheSize |
+| istiodMetrics.scrapeInterval | string | `60s` | How frequently to scrape metrics from MySQL Exporter. |
+| istiodMetrics.scrapeTimeout | string | `10s` | The timeout for scraping metrics from MySQL Exporter. |
+| istiodMetrics.tuning.excludeMetrics | list | `[]` | Metrics to drop. Can use regular expressions. |
+| istiodMetrics.tuning.includeMetrics | list | `[]` | Metrics to keep. Can use regular expressions. |
+
+### General Settings
+
+| Key | Type | Default | Description |
+|-----|------|---------|-------------|
+| jobLabel | string | `"integration/istio"` | The value of the job label for scraped metrics and logs |
+| name | string | `""` | Name for this Istio integration instance. |
+
+### Logs Settings
+
+| Key | Type | Default | Description |
+|-----|------|---------|-------------|
+| logs.enabled | bool | `true` | Whether to enable special processing of Istio pod logs. |
+
+### Discovery Settings
+
+| Key | Type | Default | Description |
+|-----|------|---------|-------------|
+| logs.labelSelectors | object | `{}` | Discover MySQL instances based on label selectors. At least one is required. |
+| logs.namespaces | list | `[]` | The namespaces to look for MySQL instances in. Will automatically look for MySQL instances in all namespaces unless specified here |
+
+### Sidecar Metrics Settings
+
+| Key | Type | Default | Description |
+|-----|------|---------|-------------|
+| sidecarMetrics.enabled | bool | `true` | Whether to enable metrics collection from Istio sidecar containers. |
+| sidecarMetrics.extraMetricProcessingRules | string | `""` | Rule blocks to be added to the prometheus.relabel component for MySQL metrics. These relabeling rules are applied post-scrape against the metrics returned from the scraped target, no `__meta*` labels are present. ([docs](https://grafana.com/docs/alloy/latest/reference/components/prometheus/prometheus.relabel/#rule-block)) |
+| sidecarMetrics.maxCacheSize | string | `100000` | Sets the max_cache_size for prometheus.relabel component. This should be at least 2x-5x your largest scrape target or samples appended rate. ([docs](https://grafana.com/docs/alloy/latest/reference/components/prometheus.relabel/#arguments)) Overrides global.maxCacheSize |
+| sidecarMetrics.scrapeInterval | string | `60s` | How frequently to scrape metrics from Istio sidecar containers. |
+| sidecarMetrics.scrapeTimeout | string | `10s` | The timeout for scraping metrics from Istio sidecar containers. |
+| sidecarMetrics.sidecarContainerName | string | `"istio-proxy.*"` | The name of the Istio sidecar container. |
+| sidecarMetrics.tuning.excludeMetrics | list | `[]` | Metrics to drop. Can use regular expressions. |
+| sidecarMetrics.tuning.includeMetrics | list | `[]` | Metrics to keep. Can use regular expressions. |
+
+### Metric Processing Settings
+
+| Key | Type | Default | Description |
+|-----|------|---------|-------------|
+| sidecarMetrics.tuning.useDefaultAllowList | bool | `true` | Filter the list of metrics from Grafana Alloy to the minimal set required for the Grafana Alloy integration. |
+
+### Other Values
+
+| Key | Type | Default | Description |
+|-----|------|---------|-------------|
+| istiodMetrics.namespace | string | `""` |  |
+| istiodMetrics.serviceName | string | `"istiod"` |  |
+| sidecarMetrics.labelSelectors | object | `{}` |  |
diff --git a/charts/k8s-monitoring/charts/feature-integrations/integrations/istio-values.yaml b/charts/k8s-monitoring/charts/feature-integrations/integrations/istio-values.yaml
new file mode 100644
index 0000000000..5ef5decff1
--- /dev/null
+++ b/charts/k8s-monitoring/charts/feature-integrations/integrations/istio-values.yaml
@@ -0,0 +1,112 @@
+---
+# -- Name for this Istio integration instance.
+# @section -- General Settings
+name: ""
+
+# -- The value of the job label for scraped metrics and logs
+# @section -- General Settings
+jobLabel: integration/istio
+
+sidecarMetrics:
+  # -- Whether to enable metrics collection from Istio sidecar containers.
+  # @section -- Sidecar Metrics Settings
+  enabled: true
+
+  labelSelectors: {}
+
+  # -- The name of the Istio sidecar container.
+  # @section -- Sidecar Metrics Settings
+  sidecarContainerName: "istio-proxy.*"
+
+  # -- How frequently to scrape metrics from Istio sidecar containers.
+  # @default -- `60s`
+  # @section -- Sidecar Metrics Settings
+  scrapeInterval:
+
+  # -- The timeout for scraping metrics from Istio sidecar containers.
+  # @default -- `10s`
+  # @section -- Sidecar Metrics Settings
+  scrapeTimeout: ""
+
+  # -- Sets the max_cache_size for prometheus.relabel component.
+  # This should be at least 2x-5x your largest scrape target or samples appended rate.
+  # ([docs](https://grafana.com/docs/alloy/latest/reference/components/prometheus.relabel/#arguments))
+  # Overrides global.maxCacheSize
+  # @default -- `100000`
+  # @section -- Sidecar Metrics Settings
+  maxCacheSize:
+
+  # Adjustments to the scraped metrics to filter the amount of data sent to storage.
+  tuning:
+    # -- Filter the list of metrics from Grafana Alloy to the minimal set required for the Grafana Alloy integration.
+    # @section -- Metric Processing Settings
+    useDefaultAllowList: true
+    # -- Metrics to keep. Can use regular expressions.
+    # @section -- Sidecar Metrics Settings
+    includeMetrics: []
+    # -- Metrics to drop. Can use regular expressions.
+    # @section -- Sidecar Metrics Settings
+    excludeMetrics: []
+
+  # -- Rule blocks to be added to the prometheus.relabel component for MySQL metrics.
+  # These relabeling rules are applied post-scrape against the metrics returned from the scraped target, no `__meta*` labels are present.
+  # ([docs](https://grafana.com/docs/alloy/latest/reference/components/prometheus/prometheus.relabel/#rule-block))
+  # @section -- Sidecar Metrics Settings
+  extraMetricProcessingRules: ""
+
+istiodMetrics:
+  # -- Whether to enable metrics collection from Istio .
+  # @section -- Istiod Metrics Settings
+  enabled: true
+
+  serviceName: istiod
+
+  namespace: ""
+
+  # -- How frequently to scrape metrics from MySQL Exporter.
+  # @default -- `60s`
+  # @section -- Istiod Metrics Settings
+  scrapeInterval:
+
+  # -- The timeout for scraping metrics from MySQL Exporter.
+  # @default -- `10s`
+  # @section -- Istiod Metrics Settings
+  scrapeTimeout: ""
+
+  # -- Sets the max_cache_size for prometheus.relabel component.
+  # This should be at least 2x-5x your largest scrape target or samples appended rate.
+  # ([docs](https://grafana.com/docs/alloy/latest/reference/components/prometheus.relabel/#arguments))
+  # Overrides global.maxCacheSize
+  # @default -- `100000`
+  # @section -- Istiod Metrics Settings
+  maxCacheSize:
+
+  # Adjustments to the scraped metrics to filter the amount of data sent to storage.
+  tuning:
+    # -- Metrics to keep. Can use regular expressions.
+    # @section -- Istiod Metrics Settings
+    includeMetrics: []
+    # -- Metrics to drop. Can use regular expressions.
+    # @section -- Istiod Metrics Settings
+    excludeMetrics: []
+
+  # -- Rule blocks to be added to the prometheus.relabel component for MySQL metrics.
+  # These relabeling rules are applied post-scrape against the metrics returned from the scraped target, no `__meta*` labels are present.
+  # ([docs](https://grafana.com/docs/alloy/latest/reference/components/prometheus/prometheus.relabel/#rule-block))
+  # @section -- Istiod Metrics Settings
+  extraMetricProcessingRules: ""
+
+# Settings for log gathering using the Pod Logs feature
+logs:
+  # -- Whether to enable special processing of Istio pod logs.
+  # @section -- Logs Settings
+  enabled: true
+
+  # -- The namespaces to look for MySQL instances in.
+  # Will automatically look for MySQL instances in all namespaces unless specified here
+  # @section -- Discovery Settings
+  namespaces: []
+
+  # -- Discover MySQL instances based on label selectors. At least one is required.
+  # @section -- Discovery Settings
+  labelSelectors: {}
diff --git a/charts/k8s-monitoring/charts/feature-integrations/schema-mods/definitions/istio-integration.schema.json b/charts/k8s-monitoring/charts/feature-integrations/schema-mods/definitions/istio-integration.schema.json
new file mode 100644
index 0000000000..0d1f03d218
--- /dev/null
+++ b/charts/k8s-monitoring/charts/feature-integrations/schema-mods/definitions/istio-integration.schema.json
@@ -0,0 +1,106 @@
+{
+    "type": "object",
+    "properties": {
+        "istiodMetrics": {
+            "type": "object",
+            "properties": {
+                "enabled": {
+                    "type": "boolean"
+                },
+                "extraMetricProcessingRules": {
+                    "type": "string"
+                },
+                "maxCacheSize": {
+                    "type": "null"
+                },
+                "namespace": {
+                    "type": "string"
+                },
+                "scrapeInterval": {
+                    "type": "null"
+                },
+                "scrapeTimeout": {
+                    "type": "string"
+                },
+                "serviceName": {
+                    "type": "string"
+                },
+                "tuning": {
+                    "type": "object",
+                    "properties": {
+                        "excludeMetrics": {
+                            "type": "array"
+                        },
+                        "includeMetrics": {
+                            "type": "array"
+                        }
+                    }
+                }
+            }
+        },
+        "jobLabel": {
+            "type": "string"
+        },
+        "logs": {
+            "type": "object",
+            "properties": {
+                "enabled": {
+                    "type": "boolean"
+                },
+                "labelSelectors": {
+                    "type": "object"
+                },
+                "namespaces": {
+                    "type": "array"
+                }
+            }
+        },
+        "name": {
+            "type": "string"
+        },
+        "sidecarMetrics": {
+            "type": "object",
+            "properties": {
+                "enabled": {
+                    "type": "boolean"
+                },
+                "extraMetricProcessingRules": {
+                    "type": "string"
+                },
+                "labelSelectors": {
+                    "type": "object"
+                },
+                "maxCacheSize": {
+                    "type": "null"
+                },
+                "scrapeInterval": {
+                    "type": "null"
+                },
+                "scrapeTimeout": {
+                    "type": "string"
+                },
+                "sidecarContainerName": {
+                    "type": "string"
+                },
+                "tuning": {
+                    "type": "object",
+                    "properties": {
+                        "excludeMetrics": {
+                            "type": "array"
+                        },
+                        "includeMetrics": {
+                            "type": "array"
+                        },
+                        "useDefaultAllowList": {
+                            "type": "boolean"
+                        }
+                    }
+                }
+            }
+        },
+        "type": {
+            "type": "string",
+            "const": "istio"
+        }
+    }
+}
diff --git a/charts/k8s-monitoring/charts/feature-integrations/schema-mods/integration-list.json b/charts/k8s-monitoring/charts/feature-integrations/schema-mods/integration-list.json
index bce6dc5023..7060890589 100644
--- a/charts/k8s-monitoring/charts/feature-integrations/schema-mods/integration-list.json
+++ b/charts/k8s-monitoring/charts/feature-integrations/schema-mods/integration-list.json
@@ -9,6 +9,7 @@
           { "$ref": "#/definitions/dcgm-exporter-integration"},
           { "$ref": "#/definitions/etcd-integration"},
           { "$ref": "#/definitions/grafana-integration"},
+          { "$ref": "#/definitions/istio-integration"},
           { "$ref": "#/definitions/loki-integration"},
           { "$ref": "#/definitions/mimir-integration"},
           { "$ref": "#/definitions/mysql-integration"},
diff --git a/charts/k8s-monitoring/charts/feature-integrations/templates/_helpers.tpl b/charts/k8s-monitoring/charts/feature-integrations/templates/_helpers.tpl
index 633b8b8546..4861fe8496 100644
--- a/charts/k8s-monitoring/charts/feature-integrations/templates/_helpers.tpl
+++ b/charts/k8s-monitoring/charts/feature-integrations/templates/_helpers.tpl
@@ -13,6 +13,9 @@
 {{- define "pod_label" -}}
 {{ printf "__meta_kubernetes_pod_label_%s" (include "escape_label" .) }}
 {{- end }}
+{{- define "pod_annotation" -}}
+{{ printf "__meta_kubernetes_pod_annotation_%s" (include "escape_label" .) }}
+{{- end }}
 
 {{- define "english_list" }}
 {{- if eq (len .) 0 }}
diff --git a/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio.tpl b/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio.tpl
new file mode 100644
index 0000000000..1a20adae4f
--- /dev/null
+++ b/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio.tpl
@@ -0,0 +1,8 @@
+{{- define "integrations.istio.validate" }}
+  {{- range $instance := $.Values.istio.instances }}
+    {{- $defaultValues := fromYaml ($.Files.Get "integrations/istio-values.yaml") }}
+    {{- include "integrations.istio.instance.validate" (dict "instance" (mergeOverwrite $defaultValues $instance (dict "type" "integration.istio"))) | nindent 2 }}
+  {{- end }}
+{{- end }}
+
+{{- define "integrations.istio.instance.validate" }}{{- end }}
diff --git a/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio_logs.tpl b/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio_logs.tpl
new file mode 100644
index 0000000000..3fbcea0de5
--- /dev/null
+++ b/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio_logs.tpl
@@ -0,0 +1,84 @@
+{{/* Inputs: . (Values) */}}
+{{- define "integrations.istio.type.logOutput" }}false{{- end }}
+
+{{/* Inputs: . (Values) */}}
+{{- define "integrations.istio.type.logRules" }}
+{{- $defaultValues := "integrations/istio-values.yaml" | .Files.Get | fromYaml }}
+{{- $logsEnabled := false }}
+{{- range $instance := .Values.istio.instances }}
+  {{- $logsEnabled = or $logsEnabled (dig "logs" "enabled" true $instance) }}
+{{- end }}
+{{- $logsEnabled -}}
+{{- end }}
+
+{{- define "integrations.istio.logs.discoveryRules" }}
+  {{- range $instance := $.Values.istio.instances }}
+    {{- if ne (dig "logs" "enabled" true $instance) false }}
+      {{- $labelList := list }}
+      {{- $valueList := list }}
+      {{- if .logs.namespaces }}
+        {{- $labelList = append $labelList "__meta_kubernetes_namespace" -}}
+        {{- $valueList = append $valueList (printf "(?:%s)" (join "|" .logs.namespaces)) -}}
+      {{- end }}
+      {{- range $k, $v := .logs.labelSelectors }}
+        {{- if kindIs "slice" $v }}
+          {{- $labelList = append $labelList (include "pod_label" $k) -}}
+          {{- $valueList = append $valueList (printf "(?:%s)" (join "|" $v)) -}}
+        {{- else }}
+          {{- $labelList = append $labelList (include "pod_label" $k) -}}
+          {{- $valueList = append $valueList (printf "(?:%s)" $v) -}}
+        {{- end }}
+      {{- end }}
+rule {
+  source_labels = {{ $labelList | toJson }}
+  separator = ";"
+  regex = {{ $valueList | join ";" | quote }}
+  target_label = "integration"
+  replacement = "istio"
+}
+rule {
+  source_labels = {{ $labelList | toJson }}
+  separator = ";"
+  regex = {{ $valueList | join ";" | quote }}
+  target_label = "instance"
+  replacement = {{ $instance.name | quote }}
+}
+    {{- end }}
+  {{- end }}
+{{- end }}
+
+{{- define "integrations.istio.logs.processingStage" }}
+  {{- if eq (include "integrations.istio.type.logRules" .) "true" }}
+// Integration: Istio
+stage.match {
+  selector = "{integration=\"istio\"}"
+
+  stage.regex {
+    expression = `(?P<timestamp>.+) (?P<thread>[\d]+) \[(?P<label>.+?)\]( \[(?P<err_code>.+?)\] \[(?P<subsystem>.+?)\])? (?P<msg>.+)`
+  }
+
+  stage.labels {
+    values = {
+      level = "label",
+      err_code = "err_code",
+      subsystem = "subsystem",
+    }
+  }
+
+  stage.drop {
+    expression = "^ *$"
+    drop_counter_reason = "drop empty lines"
+  }
+
+  stage.static_labels {
+    values = {
+      job = "integrations/istio",
+    }
+  }
+
+  stage.label_drop {
+    values = ["integration"]
+  }
+}
+  {{- end }}
+{{- end }}
diff --git a/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio_metrics.tpl b/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio_metrics.tpl
new file mode 100644
index 0000000000..77e94c2859
--- /dev/null
+++ b/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_istio_metrics.tpl
@@ -0,0 +1,200 @@
+{{/* Returns the allowed metrics */}}
+{{/* Inputs: instance (Istio integration instance) Files (Files object) */}}
+{{- define "integrations.istio.sidecar.allowList" }}
+{{- $allowList := list }}
+{{- if .instance.sidecarMetrics.tuning.useDefaultAllowList -}}
+{{- $allowList = concat $allowList (list "up" "scrape_samples_scraped") (.Files.Get "default-allow-lists/istio.yaml" | fromYamlArray) -}}
+{{- end -}}
+{{- if .instance.sidecarMetrics.tuning.includeMetrics -}}
+{{- $allowList = concat $allowList (list "up" "scrape_samples_scraped") .instance.sidecarMetrics.tuning.includeMetrics -}}
+{{- end -}}
+{{ $allowList | uniq | toYaml }}
+{{- end -}}
+{{/* Returns the allowed metrics */}}
+{{/* Inputs: instance (Istio integration instance) Files (Files object) */}}
+{{- define "integrations.istio.istiod.allowList" }}
+{{- $allowList := list }}
+{{- if .instance.istiodMetrics.tuning.useDefaultAllowList -}}
+{{- $allowList = concat $allowList (list "up" "scrape_samples_scraped") (.Files.Get "default-allow-lists/istio.yaml" | fromYamlArray) -}}
+{{- end -}}
+{{- if .instance.istiodMetrics.tuning.includeMetrics -}}
+{{- $allowList = concat $allowList (list "up" "scrape_samples_scraped") .instance.istiodMetrics.tuning.includeMetrics -}}
+{{- end -}}
+{{ $allowList | uniq | toYaml }}
+{{- end -}}
+
+{{/* Inputs: . (Values) */}}
+{{- define "integrations.istio.type.metrics" }}
+{{- $defaultValues := "integrations/istio-values.yaml" | .Files.Get | fromYaml }}
+{{- $metricsEnabled := false }}
+{{- range $instance := .Values.istio.instances }}
+  {{- $metricsEnabled = or $metricsEnabled (dig "metrics" "enabled" true $instance) }}
+{{- end }}
+{{- $metricsEnabled -}}
+{{- end }}
+
+{{- define "integrations.istio.module.metrics" }}
+declare "istio_integration" {
+  argument "metrics_destinations" {
+    comment = "Must be a list of metric destinations where collected metrics should be forwarded to"
+  }
+  {{- range $instance := $.Values.istio.instances }}
+    {{- include "integrations.istio.include.metrics" (deepCopy $ | merge (dict "instance" $instance)) | nindent 2 }}
+  {{- end }}
+}
+{{- end }}
+
+{{/* Inputs: . (Values), instance (this Istio instance) */}}
+{{- define "integrations.istio.include.metrics" }}
+{{- $defaultValues := "integrations/istio-values.yaml" | .Files.Get | fromYaml }}
+{{- with mergeOverwrite $defaultValues .instance (dict "type" "integration.istio") }}
+  {{- if .sidecarMetrics.enabled }}
+    {{- $metricAllowList := include "integrations.istio.sidecar.allowList" (dict "instance" . "Files" $.Files) | fromYamlArray }}
+    {{- $metricDenyList := .sidecarMetrics.tuning.excludeMetrics }}
+discovery.kubernetes {{ printf "%s_sidecar" (include "helper.alloy_name" .name) | quote }} {
+  role = "pod"
+  // TODO: Add label selectors
+}
+
+discovery.relabel {{ printf "%s_sidecar" (include "helper.alloy_name" .name) | quote }} {
+  targets = discovery.kubernetes.{{ printf "%s_sidecar" (include "helper.alloy_name" .name) }}.targets
+
+  rule {
+    source_labels = ["__meta_kubernetes_pod_container_name"]
+    regex         = {{ .sidecarMetrics.sidecarContainerName | quote }}
+    action        = "keep"
+  }
+  rule {
+    source_labels = [{{ include "pod_annotation" "prometheus.io/port" | quote }}, "__meta_kubernetes_pod_ip"]
+    regex = "(\\d+);(([A-Fa-f0-9]{1,4}::?){1,7}[A-Fa-f0-9]{1,4})"
+    replacement = "[$2]:$1" // IPv6
+    target_label = "__address__"
+  }
+  rule {
+    source_labels = [{{ include "pod_annotation" "prometheus.io/port" | quote }}, "__meta_kubernetes_pod_ip"]
+    regex = "(\\d+);((([0-9]+?)(\\.|$)){4})" // IPv4, takes priority over IPv6 when both exists
+    replacement = "$2:$1"
+    target_label = "__address__"
+  }
+  rule {
+    source_labels = [{{ include "pod_annotation" "prometheus.io/path" | quote }}]
+    target_label  = "__metrics_path__"
+  }
+  rule {
+    target_label = "job"
+    replacement  = {{ .jobLabel | quote }}
+  }
+  rule {
+    source_labels = ["__meta_kubernetes_namespace", "__meta_kubernetes_pod_name"]
+    separator     = "-"
+    target_label  = "instance"
+  }
+  rule {
+    source_labels = ["__meta_kubernetes_pod_name"]
+    target_label  = "pod"
+  }
+}
+
+prometheus.scrape {{ printf "%s_sidecar" (include "helper.alloy_name" .name) | quote }} {
+  targets = discovery.relabel.{{ printf "%s_sidecar" (include "helper.alloy_name" .name) }}.output
+  scrape_interval = {{ .sidecarMetrics.scrapeInterval | default $.Values.global.scrapeInterval | quote }}
+  scrape_timeout = {{ .sidecarMetrics.scrapeTimeout | default $.Values.global.scrapeTimeout | quote }}
+  scrape_protocols = {{ $.Values.global.scrapeProtocols | toJson }}
+  scrape_classic_histograms = {{ $.Values.global.scrapeClassicHistograms }}
+  scrape_native_histograms = {{ $.Values.global.scrapeNativeHistograms }}
+  clustering {
+    enabled = true
+  }
+  forward_to = [prometheus.relabel.{{ printf "%s_sidecar" (include "helper.alloy_name" .name) }}.receiver]
+}
+
+prometheus.relabel {{ printf "%s_sidecar" (include "helper.alloy_name" .name) | quote }} {
+  max_cache_size = {{ .sidecarMetrics.maxCacheSize | default $.Values.global.maxCacheSize | int }}
+{{- if $metricAllowList }}
+  rule {
+    source_labels = ["__name__"]
+    regex = {{ $metricAllowList | join "|" | quote }}
+    action = "keep"
+  }
+{{- end }}
+{{- if $metricDenyList }}
+  rule {
+    source_labels = ["__name__"]
+    regex = {{ $metricDenyList | join "|" | quote }}
+    action = "drop"
+  }
+{{- end }}
+  forward_to = argument.metrics_destinations.value
+}
+  {{ end }}
+  {{- if .istiodMetrics.enabled }}
+    {{- $metricAllowList := include "integrations.istio.istiod.allowList" (dict "instance" . "Files" $.Files) | fromYamlArray }}
+    {{- $metricDenyList := .istiodMetrics.tuning.excludeMetrics }}
+discovery.kubernetes {{ printf "%s_istiod" (include "helper.alloy_name" .name) | quote }} {
+  role = "endpoints"
+  selectors {
+    role = "service"
+    field = "metadata.name={{ .istiodMetrics.serviceName }}"
+  }
+  // TODO: label selectors and namespace selectors
+}
+
+discovery.relabel {{ printf "%s_istiod" (include "helper.alloy_name" .name) | quote }} {
+  targets = discovery.kubernetes.{{ printf "%s_istiod" (include "helper.alloy_name" .name) }}.targets
+
+  rule {
+    source_labels = ["__meta_kubernetes_endpoint_port_name"]
+    regex         = "http-monitoring"
+    action        = "keep"
+  }
+  rule {
+    target_label = "job"
+    replacement  = {{ .jobLabel | quote }}
+  }
+  rule {
+    target_label  = "instance"
+    source_labels = ["__meta_kubernetes_namespace", "__meta_kubernetes_pod_name"]
+    separator     = "-"
+  }
+  rule {
+    target_label  = "pod"
+    action        = "replace"
+    source_labels = ["__meta_kubernetes_pod_name"]
+  }
+}
+
+prometheus.scrape {{ printf "%s_istiod" (include "helper.alloy_name" .name) | quote }} {
+  targets = discovery.relabel.{{ printf "%s_istiod" (include "helper.alloy_name" .name) }}.output
+  clustering {
+    enabled = true
+  }
+
+  scrape_interval = {{ .istiodMetrics.scrapeInterval | default $.Values.global.scrapeInterval | quote }}
+  scrape_timeout = {{ .istiodMetrics.scrapeTimeout | default $.Values.global.scrapeTimeout | quote }}
+  scrape_protocols = {{ $.Values.global.scrapeProtocols | toJson }}
+  scrape_classic_histograms = {{ $.Values.global.scrapeClassicHistograms }}
+  scrape_native_histograms = {{ $.Values.global.scrapeNativeHistograms }}
+  forward_to = [prometheus.relabel.{{ printf "%s_istiod" (include "helper.alloy_name" .name) }}.receiver]
+}
+
+prometheus.relabel {{ printf "%s_istiod" (include "helper.alloy_name" .name) | quote }} {
+  max_cache_size = {{ .istiodMetrics.maxCacheSize | default $.Values.global.maxCacheSize | int }}
+{{- if $metricAllowList }}
+  rule {
+    source_labels = ["__name__"]
+    regex = {{ $metricAllowList | join "|" | quote }}
+    action = "keep"
+  }
+{{- end }}
+{{- if $metricDenyList }}
+  rule {
+    source_labels = ["__name__"]
+    regex = {{ $metricDenyList | join "|" | quote }}
+    action = "drop"
+  }
+{{- end }}
+  forward_to = argument.metrics_destinations.value
+}
+{{- end }}
+{{- end }}
+{{- end }}
diff --git a/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_types.tpl b/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_types.tpl
index 0138cbb3c2..e4848e07c0 100644
--- a/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_types.tpl
+++ b/charts/k8s-monitoring/charts/feature-integrations/templates/_integration_types.tpl
@@ -5,6 +5,7 @@
 - dcgm-exporter
 - etcd
 - grafana
+- istio
 - loki
 - mimir
 - mysql
diff --git a/charts/k8s-monitoring/charts/feature-integrations/values.schema.json b/charts/k8s-monitoring/charts/feature-integrations/values.schema.json
index d6816f3595..c05b6f4359 100644
--- a/charts/k8s-monitoring/charts/feature-integrations/values.schema.json
+++ b/charts/k8s-monitoring/charts/feature-integrations/values.schema.json
@@ -71,6 +71,14 @@
                 }
             }
         },
+        "istio": {
+            "type": "object",
+            "properties": {
+                "instances": {
+                    "type": "array"
+                }
+            }
+        },
         "loki": {
             "type": "object",
             "properties": {
@@ -475,6 +483,112 @@
                 }
             }
         },
+        "istio-integration": {
+            "type": "object",
+            "properties": {
+                "istiodMetrics": {
+                    "type": "object",
+                    "properties": {
+                        "enabled": {
+                            "type": "boolean"
+                        },
+                        "extraMetricProcessingRules": {
+                            "type": "string"
+                        },
+                        "maxCacheSize": {
+                            "type": "null"
+                        },
+                        "namespace": {
+                            "type": "string"
+                        },
+                        "scrapeInterval": {
+                            "type": "null"
+                        },
+                        "scrapeTimeout": {
+                            "type": "string"
+                        },
+                        "serviceName": {
+                            "type": "string"
+                        },
+                        "tuning": {
+                            "type": "object",
+                            "properties": {
+                                "excludeMetrics": {
+                                    "type": "array"
+                                },
+                                "includeMetrics": {
+                                    "type": "array"
+                                }
+                            }
+                        }
+                    }
+                },
+                "jobLabel": {
+                    "type": "string"
+                },
+                "logs": {
+                    "type": "object",
+                    "properties": {
+                        "enabled": {
+                            "type": "boolean"
+                        },
+                        "labelSelectors": {
+                            "type": "object"
+                        },
+                        "namespaces": {
+                            "type": "array"
+                        }
+                    }
+                },
+                "name": {
+                    "type": "string"
+                },
+                "sidecarMetrics": {
+                    "type": "object",
+                    "properties": {
+                        "enabled": {
+                            "type": "boolean"
+                        },
+                        "extraMetricProcessingRules": {
+                            "type": "string"
+                        },
+                        "labelSelectors": {
+                            "type": "object"
+                        },
+                        "maxCacheSize": {
+                            "type": "null"
+                        },
+                        "scrapeInterval": {
+                            "type": "null"
+                        },
+                        "scrapeTimeout": {
+                            "type": "string"
+                        },
+                        "sidecarContainerName": {
+                            "type": "string"
+                        },
+                        "tuning": {
+                            "type": "object",
+                            "properties": {
+                                "excludeMetrics": {
+                                    "type": "array"
+                                },
+                                "includeMetrics": {
+                                    "type": "array"
+                                },
+                                "useDefaultAllowList": {
+                                    "type": "boolean"
+                                }
+                            }
+                        }
+                    }
+                },
+                "type": {
+                    "type": "string",
+                    "const": "istio"
+                }
+            }
+        },
         "loki-integration": {
             "type": "object",
             "properties": {
@@ -1077,6 +1191,9 @@
                     {
                         "$ref": "#/definitions/grafana-integration"
                     },
+                    {
+                        "$ref": "#/definitions/istio-integration"
+                    },
                     {
                         "$ref": "#/definitions/loki-integration"
                     },
diff --git a/charts/k8s-monitoring/charts/feature-integrations/values.yaml b/charts/k8s-monitoring/charts/feature-integrations/values.yaml
index 8f519f4f45..399c0309dc 100644
--- a/charts/k8s-monitoring/charts/feature-integrations/values.yaml
+++ b/charts/k8s-monitoring/charts/feature-integrations/values.yaml
@@ -69,6 +69,11 @@ dcgm-exporter:
 etcd:
   instances: []
 
+# -- Scrape metrics/logs from Istio sidecar and service.
+# @section -- Integration: Istio
+istio:
+  instances: []
+
 # -- Scrape metrics/logs from Grafana
 # @section -- Integration: Grafana
 grafana:
diff --git a/charts/k8s-monitoring/docs/examples/istio-service-mesh/values.yaml b/charts/k8s-monitoring/docs/examples/istio-service-mesh/values.yaml
index f822b2e6e1..c962150463 100644
--- a/charts/k8s-monitoring/docs/examples/istio-service-mesh/values.yaml
+++ b/charts/k8s-monitoring/docs/examples/istio-service-mesh/values.yaml
@@ -16,13 +16,6 @@ destinations:
     logs: {enabled: false}
     traces: {enabled: true}
 
-annotationAutodiscovery:
-  enabled: true
-  annotations:
-    scrape: prometheus.io/scrape
-    metricsPath: prometheus.io/path
-    metricsPortNumber: prometheus.io/port
-
 clusterMetrics:
   enabled: true
 
@@ -40,6 +33,15 @@ applicationObservability:
   logs:
     enabled: false
 
+integrations:
+  istio:
+    instances:
+      - name: istio
+        sidecarMetrics:
+          enabled: true
+        istiodMetrics:
+          enabled: true
+
 alloy-metrics:
   enabled: true
   alloy:
diff --git a/charts/k8s-monitoring/tests/integration/istio-service-mesh/values.yaml b/charts/k8s-monitoring/tests/integration/istio-service-mesh/values.yaml
index e849521a6c..ae2cc57190 100644
--- a/charts/k8s-monitoring/tests/integration/istio-service-mesh/values.yaml
+++ b/charts/k8s-monitoring/tests/integration/istio-service-mesh/values.yaml
@@ -28,13 +28,6 @@ destinations:
     logs: {enabled: false}
     traces: {enabled: true}
 
-annotationAutodiscovery:
-  enabled: true
-  annotations:
-    scrape: prometheus.io/scrape
-    metricsPath: prometheus.io/path
-    metricsPortNumber: prometheus.io/port
-
 clusterMetrics:
   enabled: true
 
@@ -44,6 +37,17 @@ clusterEvents:
 podLogs:
   enabled: true
 
+integrations:
+  istio:
+    instances:
+      - name: istio
+        sidecarMetrics:
+          enabled: true
+        istiodMetrics:
+          enabled: true
+        logs:
+          enabled: false
+
 applicationObservability:
   enabled: true
   receivers: