Carbon‐Constrained FBA (ccFBA) #6
Description
Kiparissides A. et al. in their study Improving the accuracy of flux balance analysis through the implementation of carbon availability constraints for intracellular reactions. (2019) they came up with a method on the basis of the elemental balance of carbon throughout the network and ensures reported flux values are consistent with the amount of carbon being taken up or secreted (Zarecki et al., 2014).
Their MATLAB implementation is not available in Python.
@SotirisTouliopoulos we could go for this, maybe open a PR to cobrapy too, and then sample using this.
Then, we could use this approach for loopless sampling.