Bio_informatics_science_technology_image_beyond_1/2025-10-15_世界上最长寿的啮齿动物种类.qmd at main · iamhealthy/Bio_informatics_science_technology_image_beyond_1 · GitHub

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---
title: 最长寿啮齿动物
subtitle: 世界上最长寿的啮齿动物种类
date: 2025-10-15
toc-depth: 4
toc-expand: true
lang: en
---

![](images/science.aeb6125-f1.jpg){width="100%"}

## 1. 裸鼹鼠（naked mole rat，*Heterocephalus glaber*）的寿命

读到一篇关于探讨裸鼹鼠的cGAS和抗衰老/anti-aging的研究论文[@Chen2025]和对应的评论[@Martinez2025]。

研究论文[@Chen2025]提到：

> The naked mole-rat (*Heterocephalus glaber*) is an extraordinarily long-lived rodent with <mark>a maximum life span of ∼37 years</mark>.

对应的评论[@Martinez2025]提到：

> The naked mole rat (*Heterocephalus glaber*) is the longest-lived rodent, with <mark>a maximum life span of nearly 40 years</mark>.

对该推文的笔者来说，算一个知识点，所以贴出来。

## 2. QuPath for fun

纯粹为了好玩，我们通过个性化groovy脚本在QuPath中标注裸鼹鼠的寿命特点。

<center>
![](images/science.aeb6125-f1_qupath.jpg){width="100%"}

![批注大概从第8秒开始。](images/science.aeb6125-f1_qupath_video.mp4)
</center>

```
// QuPath v0.6.0

import qupath.lib.objects.PathObjects
import qupath.lib.roi.ROIs

// Set image type
setImageType('OTHER')

// Remove all existed objects
selectAllObjects()
removeAllObjects()

// Sleep for 30 seconds
Thread.sleep(30000)

// Draw a line (1st)
def line_x1 = 592; line_x2 = 724
def line_y1 = 835; line_y2 = 457
def plane = getCurrentViewer().getImagePlane()
def line1_roi = ROIs.createLineROI(line_x1, line_y1, line_x2, line_y2, plane)
def line1_anno = PathObjects.createAnnotationObject(line1_roi)
addObject(line1_anno)

// Sleep for 2 seconds
Thread.sleep(2000)

// Draw another line (2nd)
def line_x3 = line_x2; line_x4 = 2500
def line_y3 = line_y2; line_y4 = line_y2
def line2_roi = ROIs.createLineROI(line_x3, line_y3, line_x4, line_y4, plane)
def line2_anno = PathObjects.createAnnotationObject(line2_roi)
addObject(line2_anno)

// Sleep for 2 seconds
Thread.sleep(2000)

// Set a name to the 2nd line
def text = "I (naked mole rat/裸鼹鼠) am the longest-lived rodent, with a maximum life span of nearly 40 years :)"
def text_annotation = text
def text_annotation_obj = PathObjects.createAnnotationObject(line2_roi)
text_annotation_obj.setName(text_annotation)
addObject(text_annotation_obj)

// Sleep for 2 seconds
Thread.sleep(2000)

// Select all objects
selectAllObjects()

println("Done!")
```

[给我买杯茶🍵](给我买杯茶.qmd)

## References