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docs/source/models/causes/maternal_disorders/gbd_2021_mncnh/index.rst

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Assumptions and Limitations
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+++++++++++++++++++++++++++
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For each of our maternal disorders subcauses, we have taken a strategy
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of calculating the amount of YLDs per incident case and assigning that
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number of YLDs to each incident case regardless of whether or not that
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simulant dies in the simulation (see the individual subcause model
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documents for specific instructions on how to model YLDs). In reality,
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while simulants who die due to a maternal disorder will accumulate YLDs
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that occur during pregnancy and acute YLDs during labor and the immediate
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postpartum period, they will not accumulate YLDs associated with long-term
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sequelae of maternal disorders subcauses. By not accounting for the difference
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in YLDs between incident cases of maternal disorders subcauses among simulants
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who survive and those who do not, we will not capture the phenomenon of
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averting maternal deaths (averting YLLs) in an intervention scenario leading to
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*increases* in maternal disorders YLDs. This will cause us to slightly overestimate
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the impact of interventions on total DALYs averted due to maternal disorders for
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interventions that reduce maternal disorders mortality.
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Cause Model Diagram
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+++++++++++++++++++
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docs/source/models/concept_models/vivarium_mncnh_portfolio/concept_model.rst

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- Ultrasound coverage
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- Ultrasound type
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- IFA/MMS coverage
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- Anemia screening coverage
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- Hemoglobin screening coverage
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- Ferritin screening coverage
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- IV iron coverage
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- Note
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* - 1. Baseline
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- Defined in the baseline coverage section of the :ref:`AI ultrasound module page <2024_vivarium_mncnh_portfolio_ai_ultrasound_module>`
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- Defined in the baseline coverage section of the :ref:`AI ultrasound module page <2024_vivarium_mncnh_portfolio_ai_ultrasound_module>`
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- Defined in the baseline coverage section of the :ref:`oral iron supplementation page <oral_iron_antenatal>`
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- XXX
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- Defined in the baseline coverage section of the :ref:`anemia screening intervention page <anemia_screening>`
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- Defined in the baseline coverage section of the :ref:`anemia screening intervention page <anemia_screening>`
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- XXX
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-
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* - 2. CPAP total scale-up
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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-
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* - 3. CPAP CEMONC-only scale-up
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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-
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* - 4. CPAP BEMONC-only scale-up
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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-
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* - 5. Antibiotics total scale-up
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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-
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* - 8. Probiotics total scale-up
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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-
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* - 9. Probiotics CEMONC-only scale-up
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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* - 11. Azithromycin V&V
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- Baseline
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- Baseline
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- Baseline
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* - 12. Misoprostol V&V
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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* - 13. Azithromycin results
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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- Baseline
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* - 14. No ACS and total CPAP V&V
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- Baseline
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* - 15. Total ACS and CPAP V&V
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- Baseline
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- Baseline
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- Baseline
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.. _MNCNH intrapartum component scenario table:
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docs/source/models/concept_models/vivarium_mncnh_portfolio/hemoglobin_component/module_document.rst

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-
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- Hemoglobin screen?
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- Coverage defined by scenario, see :ref:`pregnancy component scenario table <MNCNH intrapartum component scenario table>`. Probability of "yes" is equal to scenario-specific coverage.
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- Coverage defined by scenario, see :ref:`pregnancy component scenario table <MNCNH pregnancy component scenario table>`. Probability of "yes" is equal to scenario-specific coverage.
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- Receive IFA/MMS *for the first time* at late pregnancy visit?
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- Coverage defined by scenario, see :ref:`pregnancy component scenario table <MNCNH intrapartum component scenario table>`. If answer to decision node #3 is no, then answer to this decision node is also no. Otherwise, probability of "yes" is equal to scenario-specific coverage.
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- Coverage defined by scenario, see :ref:`pregnancy component scenario table <MNCNH pregnancy component scenario table>`. If answer to decision node #3 is no, then answer to this decision node is also no. Otherwise, probability of "yes" is equal to scenario-specific coverage.
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- Use same propensity value as decision node #1 to answer this question
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* - 7
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- Hemoglobin screening value <100 g/L? (Based on IFA/MMS adjusted exposure)
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- Instructions detailed on the :ref:`anemia screening intervention page <anemia_screening>`
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- Ferritin screen?
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- Coverage defined by scenario, see :ref:`pregnancy component scenario table <MNCNH pregnancy component scenario table>`. Probability of "yes" is equal to scenario-specific coverage
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-
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- Low ferritin screening value?
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- Instructions detailed on the :ref:`anemia screening intervention page <anemia_screening>`
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- IV iron?
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- Coverage defined by scenario, see :ref:`pregnancy component scenario table <MNCNH intrapartum component scenario table>`. Probability of "yes" is equal to scenario-specific coverage.
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- Coverage defined by scenario, see :ref:`pregnancy component scenario table <MNCNH pregnancy component scenario table>`. Probability of "yes" is equal to scenario-specific coverage.
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- Also receive IFA/MMS *for the first time* at late pregnancy visit?
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- Coverage defined by scenario, see :ref:`pregnancy component scenario table <MNCNH intrapartum component scenario table>`. If answer to decision node #3 is no, then answer to this decision node is also no. Otherwise, probability of "yes" is equal to scenario-specific coverage.
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- Use same propensity value as decision node #1 to answer this question

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