Model 13.1 vv

Author: Ali Bowman

docs/source/models/concept_models/vivarium_mncnh_portfolio/concept_model.rst

@@ -1667,8 +1667,13 @@ Default stratifications to all observers should include scenario and input draw.
       * Confirm RR values for hemoglobin exposures <40 are equal to the RR value for a hemoglobin exposure of 40
       * Confirm that artifact RR values match expectation
       * Confirm that RR values for hemoglobin exposures above the TMREL vary according to the input data
-    - 
-    -
+    - * Slight overestimation of maternal sepsis incidence, particularly in Nigeria. Mean values are generally within 10% of target otherwise. Significant draw-level variation, with underestimation of lower draws and overestimation of higher draws.
+      * Hemoglobin exposure appropriately modifies maternal disorder incidence but not mortality
+      * RR values for hemoglobin exposures <40 equal that of hemoglobin exposure equal to 40
+      * Artifact RR values match expectation
+      * RR values for hemoglobin exposures >TMREL vary according to input data 
+    - * `Model 13.1 maternal checks notebook <https://github.com/ihmeuw/vivarium_research_mncnh_portfolio/blob/main/verification_and_validation/model_13.1_maternal_checks.ipynb>`_
+      * `Model 13.1 interactive sim notebook <https://github.com/ihmeuw/vivarium_research_mncnh_portfolio/blob/main/verification_and_validation/model_13.1_interactive_simulation_hemoglobin.ipynb>`_
   * - 13.2
     - * Check late neonatal all-cause mortality risk and cause-specific mortality risks;
         expected change is small but should be in the direction of better verification to GBD
@@ -1785,18 +1790,10 @@ Default stratifications to all observers should include scenario and input draw.
     - Explanation
     - Action plan
     - Timeline
-  * - RR values for hemoglobin < 40 g/L not as expected
-    - All hemoglobin exposures less than 40 g/L should be assigned the RR for the 40 g/L exposure
-    - Hussain to update implementation accordingly
-    - For 13.1
-  * - RR values for hemoglobin exposures above the TMREL all equal 1
-    - They should be able to match input data for values not equal to 1 (greater than lower than one are both okay)
-    - Hussain to update implementation accordingly
-    - For 13.1
-  * - Miscalibration of maternal hemorrhage and sepsis incidence rates
-    - Due to non-location-specific hemoglobin PAF value
-    - Hussain to update
-    - For 13.1
+  * - Miscalibration of maternal sepsis incidence rates, particularly for Nigeria
+    - Thought to be due to using the fatal PAF from GBD applied to incidence and/or the location-aggregated PAF for our modeled locations which are not most detailed locations
+    - Update to custom-calculated PAF and reasses
+    - TBD
   * - Issue with LBWSG PAF calculation for the late neonatal age group
     - See the summary in the model 12.1.1 run request
     - Hussain to update and rerun, Ali to do independent replication of PAF calculation verification