diff --git a/pytest_watch/command.py b/pytest_watch/command.py
index 4a8d84e..0d25033 100644
--- a/pytest_watch/command.py
+++ b/pytest_watch/command.py
@@ -13,6 +13,9 @@
   --ext <exts>          Comma-separated list of file extensions that can
                         trigger a new test run when changed (default: .py).
                         Use --ext=* to allow any file (including .pyc).
+  --skip <glob>         A glob, all events matching the mask will be ignored.
+                        Multiple masks are supported, comma separated (no space).
+                        Use --skip .#*.py,flycheck_*.py to ignore Emacs temp files.
   --config <file>       Load configuration from `file` instead of trying to
                         locate one of the implicit configuration files.
   -c --clear            Clear the screen before each run.
@@ -79,6 +82,10 @@ def main(argv=None):
     if args['--config']:
         pytest_args.extend(['-c', args['--config']])
 
+    skip_masks = []
+    if args['--skip']:
+        skip_masks = args['--skip'].split(',')
+
     # Merge config file options
     if not merge_config(args, pytest_args, verbose=args['--verbose']):
         return 0
@@ -109,6 +116,7 @@ def main(argv=None):
     return watch(entries=directories,
                  ignore=args['--ignore'],
                  extensions=extensions,
+                 skip_masks=skip_masks,
                  beep_on_failure=not args['--nobeep'],
                  auto_clear=args['--clear'],
                  wait=args['--wait'] or '--pdb' in pytest_args,
diff --git a/pytest_watch/watcher.py b/pytest_watch/watcher.py
index f69497f..4724e19 100644
--- a/pytest_watch/watcher.py
+++ b/pytest_watch/watcher.py
@@ -5,6 +5,7 @@
 import subprocess
 import time
 from traceback import format_exc
+from pathlib import Path
 
 try:
     from queue import Queue
@@ -77,10 +78,12 @@ class EventListener(FileSystemEventHandler):
     """
     Listens for changes to files and re-runs tests after each change.
     """
-    def __init__(self, extensions=[], event_queue=None):
+
+    def __init__(self, extensions=[], skip_masks=[], event_queue=None):
         super(EventListener, self).__init__()
         self.event_queue = event_queue or Queue()
         self.extensions = extensions or DEFAULT_EXTENSIONS
+        self.skip_masks = skip_masks
 
     def on_any_event(self, event):
         """
@@ -99,7 +102,8 @@ def on_any_event(self, event):
         # Filter files that don't match the allowed extensions
         if not event.is_directory and self.extensions != ALL_EXTENSIONS:
             src_ext = os.path.splitext(src_path)[1].lower()
-            src_included = src_ext in self.extensions
+            should_skip = any([Path(src_path).match(mask) for mask in self.skip_masks])
+            src_included = src_ext in self.extensions and not should_skip
             dest_included = False
             if dest_path:
                 dest_ext = os.path.splitext(dest_path)[1].lower()
@@ -216,7 +220,7 @@ def run_hook(cmd, *args):
         subprocess.call(command, shell=True)
 
 
-def watch(entries=[], ignore=[], extensions=[], beep_on_failure=True,
+def watch(entries=[], ignore=[], extensions=[], skip_masks=[], beep_on_failure=True,
           auto_clear=False, wait=False, beforerun=None, afterrun=None,
           onpass=None, onfail=None, onexit=None, runner=None, spool=None,
           poll=False, verbose=False, quiet=False, pytest_args=[]):
@@ -237,7 +241,7 @@ def watch(entries=[], ignore=[], extensions=[], beep_on_failure=True,
             raise ValueError('Directory not found: ' + entry)
 
     # Setup event handler
-    event_listener = EventListener(extensions)
+    event_listener = EventListener(extensions, skip_masks=skip_masks)
 
     # Setup watchdog
     observer = PollingObserver() if poll else Observer()