diff --git a/README.md b/README.md
index 6c5e69b..25ba295 100644
--- a/README.md
+++ b/README.md
@@ -47,6 +47,8 @@ commands.
 - `publish`: Publish `package.json` libraries to JSR.
 - `run <script>`: Run a JSR package script.
 - `<script>`: Run a JSR package script without `run` command.
+- `setup`: Set up the project for JSR. Add the settings for mapping @jsr scope
+  to JSR registry.
 
 ## Limitations
 
diff --git a/src/bin.ts b/src/bin.ts
index 04e6d61..f713ec0 100644
--- a/src/bin.ts
+++ b/src/bin.ts
@@ -9,6 +9,7 @@ import {
   publish,
   remove,
   runScript,
+  setup,
   showPackageInfo,
 } from "./commands";
 import {
@@ -58,6 +59,10 @@ ${
       ["r, uninstall, remove", "Remove one or more JSR packages."],
       ["publish", "Publish a package to the JSR registry."],
       ["info, show, view", "Show package information."],
+      [
+        "setup",
+        "Set up the project for JSR. Add the settings for mapping @jsr scope to JSR registry.",
+      ],
     ])
   }
 
@@ -238,6 +243,10 @@ if (args.length === 0) {
       run(async () => {
         await runScript(process.cwd(), script, { pkgManagerName });
       });
+    } else if (cmd === "setup") {
+      run(async () => {
+        await setup({ pkgManagerName });
+      });
     } else {
       const packageJsonPath = path.join(process.cwd(), "package.json");
       if (fs.existsSync(packageJsonPath)) {
diff --git a/src/commands.ts b/src/commands.ts
index d51171c..8afdd0e 100644
--- a/src/commands.ts
+++ b/src/commands.ts
@@ -9,7 +9,13 @@ import {
   JsrPackage,
   timeAgo,
 } from "./utils";
-import { Bun, getPkgManager, PkgManagerName, YarnBerry } from "./pkg_manager";
+import {
+  Bun,
+  getPkgManager,
+  PackageManager,
+  PkgManagerName,
+  YarnBerry,
+} from "./pkg_manager";
 import { downloadDeno, getDenoDownloadUrl } from "./download";
 import { getNpmPackageInfo, getPackageMeta } from "./api";
 import semiver from "semiver";
@@ -79,6 +85,23 @@ export async function setupBunfigToml(dir: string) {
   }
 }
 
+/** Adds settings to map `@jsr` scope to https://npm.jsr.io registry for the given package manager */
+async function setupJsrScope(dir: string, pkgManager: PackageManager) {
+  if (pkgManager instanceof Bun) {
+    // Bun doesn't support reading from .npmrc yet
+    await setupBunfigToml(dir);
+  } else if (pkgManager instanceof YarnBerry) {
+    // Yarn v2+ does not read from .npmrc intentionally
+    // https://yarnpkg.com/migration/guide#update-your-configuration-to-the-new-settings
+    await pkgManager.setConfigValue(
+      JSR_YARN_BERRY_CONFIG_KEY,
+      JSR_NPM_REGISTRY_URL,
+    );
+  } else {
+    await setupNpmRc(dir);
+  }
+}
+
 export interface BaseOptions {
   pkgManagerName: PkgManagerName | null;
 }
@@ -94,26 +117,22 @@ export async function install(packages: JsrPackage[], options: InstallOptions) {
   );
 
   if (packages.length > 0) {
-    if (pkgManager instanceof Bun) {
-      // Bun doesn't support reading from .npmrc yet
-      await setupBunfigToml(root);
-    } else if (pkgManager instanceof YarnBerry) {
-      // Yarn v2+ does not read from .npmrc intentionally
-      // https://yarnpkg.com/migration/guide#update-your-configuration-to-the-new-settings
-      await pkgManager.setConfigValue(
-        JSR_YARN_BERRY_CONFIG_KEY,
-        JSR_NPM_REGISTRY_URL,
-      );
-    } else {
-      await setupNpmRc(root);
-    }
-
+    await setupJsrScope(root, pkgManager);
     console.log(`Installing ${kl.cyan(packages.join(", "))}...`);
   }
 
   await pkgManager.install(packages, options);
 }
 
+export async function setup(options: BaseOptions) {
+  const { pkgManager, root } = await getPkgManager(
+    process.cwd(),
+    options.pkgManagerName,
+  );
+
+  await setupJsrScope(root, pkgManager);
+}
+
 export async function remove(packages: JsrPackage[], options: BaseOptions) {
   const { pkgManager } = await getPkgManager(
     process.cwd(),
diff --git a/test/commands.test.ts b/test/commands.test.ts
index 6c58702..28a5e2e 100644
--- a/test/commands.test.ts
+++ b/test/commands.test.ts
@@ -196,7 +196,7 @@ describe("install", () => {
 
       assert.match(
         pkgJson.dependencies["@std/encoding"],
-        /^npm:@jsr\/std__encoding@\^\d+\.\d+\.\d+.*$/,
+        /^npm:@jsr\/std__encoding@\^?\d+\.\d+\.\d+.*$/,
       );
 
       const npmRc = await readTextFile(path.join(dir, ".npmrc"));
@@ -801,3 +801,42 @@ describe("show", () => {
     assert.ok(txt.includes("npm tarball:"));
   });
 });
+
+describe("setup", () => {
+  it("jsr setup - should generate .npmrc file", async () => {
+    await runInTempDir(async (dir) => {
+      await runJsr(["setup"], dir);
+
+      const npmrcPath = path.join(dir, ".npmrc");
+      const npmRc = await readTextFile(npmrcPath);
+      assert.ok(
+        npmRc.includes("@jsr:registry=https://npm.jsr.io"),
+        "Missing npmrc registry",
+      );
+    });
+  });
+
+  it("jsr setup - should generate .yarnrc.yml if yarn berry is detected", async () => {
+    await runInTempDir(async (dir) => {
+      await enableYarnBerry(dir);
+      await writeTextFile(path.join(dir, "yarn.lock"), "");
+
+      await runJsr(["setup"], dir);
+
+      const yarnRc = await readTextFile(path.join(dir, ".yarnrc.yml"));
+      assert.ok(
+        /jsr:\s*npmRegistryServer: "https:\/\/npm\.jsr\.io"/.test(yarnRc),
+        "Missing yarnrc.yml registry",
+      );
+    });
+  });
+
+  it("jsr setup - should generate bunfig.toml if bun is detected", async () => {
+    await runInTempDir(async (dir) => {
+      await runJsr(["setup", "--bun"], dir);
+
+      const config = await readTextFile(path.join(dir, "bunfig.toml"));
+      assert.match(config, /"@jsr"\s+=/, "bunfig.toml not created");
+    });
+  });
+});