diff --git a/__tests__/src/rules/no-disabled-test.js b/__tests__/src/rules/no-disabled-test.js
new file mode 100644
index 000000000..97ce04d4b
--- /dev/null
+++ b/__tests__/src/rules/no-disabled-test.js
@@ -0,0 +1,53 @@
+/* eslint-env jest */
+/**
+ * @fileoverview Enforce disabled prop is not used unless specifically intended.
+ * @author Courtney Nguyen <@courtyenn>
+ */
+
+// -----------------------------------------------------------------------------
+// Requirements
+// -----------------------------------------------------------------------------
+
+import { RuleTester } from 'eslint';
+import rule from '../../../src/rules/no-disabled';
+import parserOptionsMapper from '../../__util__/parserOptionsMapper';
+
+// -----------------------------------------------------------------------------
+// Tests
+// -----------------------------------------------------------------------------
+
+const ruleTester = new RuleTester();
+
+const expectedWarning = {
+  message: 'The disabled prop removes the element from being detected by screen readers.',
+  type: 'JSXAttribute',
+};
+
+ruleTester.run('no-disabled', rule, {
+  valid: [
+    { code: '<div />' },
+    { code: '<div disabled />' },
+    { code: '<input />' },
+    { code: '<button />' },
+    { code: '<select />' },
+    { code: '<textarea />' },
+    { code: '<option />' },
+    { code: '<command />' },
+    { code: '<fieldset />' },
+    { code: '<keygen />' },
+    { code: '<optgroup />' },
+  ].map(parserOptionsMapper),
+  invalid: [
+    { code: '<input disabled />', errors: [expectedWarning] },
+    { code: '<input disabled="true" />', errors: [expectedWarning] },
+    { code: '<input disabled="false" />', errors: [expectedWarning] },
+    { code: '<button disabled />', errors: [expectedWarning] },
+    { code: '<select disabled />', errors: [expectedWarning] },
+    { code: '<textarea disabled />', errors: [expectedWarning] },
+    { code: '<option disabled />', errors: [expectedWarning] },
+    { code: '<command disabled />', errors: [expectedWarning] },
+    { code: '<fieldset disabled />', errors: [expectedWarning] },
+    { code: '<keygen disabled />', errors: [expectedWarning] },
+    { code: '<optgroup disabled />', errors: [expectedWarning] },
+  ].map(parserOptionsMapper),
+});
diff --git a/docs/rules/no-disabled.md b/docs/rules/no-disabled.md
new file mode 100644
index 000000000..8733f32eb
--- /dev/null
+++ b/docs/rules/no-disabled.md
@@ -0,0 +1,28 @@
+# no-disabled
+
+Rule that `disabled` prop should be cautioned on elements. Disabling interactive elements removes the element from the accessibility tree. Consider using `aria-disabled`.
+
+## Rule details
+The general consensus is that `disabled` should be used with specific intent. It goes against intuition since `disabled` is a native HTML attribute, which disables. However, from a usability stand-point it is not a good UX for screen readers: It removes the element from the a11y tree, and may omit critical information. It is best to use `aria-disabled` and add the additional JS logic to "disable" the element.
+
+### Succeed
+```jsx
+<div />
+<div disabled />
+<input />
+<select />
+<textarea />
+<button />
+```
+
+### Fail
+```jsx
+<input disabled />
+<input disabled="true" />
+<input disabled="false" />
+<input disabled={undefined} />
+```
+
+### Resources
+- [MDN aria-disabled](https://developer.mozilla.org/en-US/docs/Web/Accessibility/ARIA/Attributes/aria-disabled)
+- [W3 KBD Disabled Controls](https://www.w3.org/TR/wai-aria-practices/#kbd_disabled_controls)
diff --git a/src/index.js b/src/index.js
index 052e0f163..12faf9d3b 100644
--- a/src/index.js
+++ b/src/index.js
@@ -26,6 +26,7 @@ module.exports = {
     'mouse-events-have-key-events': require('./rules/mouse-events-have-key-events'),
     'no-access-key': require('./rules/no-access-key'),
     'no-autofocus': require('./rules/no-autofocus'),
+    'no-disabled': require('./rules/no-disabled'),
     'no-distracting-elements': require('./rules/no-distracting-elements'),
     'no-interactive-element-to-noninteractive-role': require('./rules/no-interactive-element-to-noninteractive-role'),
     'no-noninteractive-element-interactions': require('./rules/no-noninteractive-element-interactions'),
@@ -113,6 +114,19 @@ module.exports = {
         'jsx-a11y/mouse-events-have-key-events': 'error',
         'jsx-a11y/no-access-key': 'error',
         'jsx-a11y/no-autofocus': 'error',
+        'jsx-a11y/no-disabled': ['warn', {
+          disabable: [
+            'button',
+            'command',
+            'fieldset',
+            'keygen',
+            'optgroup',
+            'option',
+            'select',
+            'textarea',
+            'input',
+          ],
+        }],
         'jsx-a11y/no-distracting-elements': 'error',
         'jsx-a11y/no-interactive-element-to-noninteractive-role': [
           'error',
@@ -270,6 +284,19 @@ module.exports = {
         'jsx-a11y/mouse-events-have-key-events': 'error',
         'jsx-a11y/no-access-key': 'error',
         'jsx-a11y/no-autofocus': 'error',
+        'jsx-a11y/no-disabled': ['warn', {
+          disabable: [
+            'button',
+            'command',
+            'fieldset',
+            'keygen',
+            'optgroup',
+            'option',
+            'select',
+            'textarea',
+            'input',
+          ],
+        }],
         'jsx-a11y/no-distracting-elements': 'error',
         'jsx-a11y/no-interactive-element-to-noninteractive-role': 'error',
         'jsx-a11y/no-noninteractive-element-interactions': [
diff --git a/src/rules/no-disabled.js b/src/rules/no-disabled.js
new file mode 100644
index 000000000..1292921f0
--- /dev/null
+++ b/src/rules/no-disabled.js
@@ -0,0 +1,64 @@
+/**
+ * @fileoverview Rule to flag 'disabled' prop
+ * @author Courtney Nguyen <@courtyenn>
+ */
+
+// ----------------------------------------------------------------------------
+// Rule Definition
+// ----------------------------------------------------------------------------
+
+import { propName, elementType } from 'jsx-ast-utils';
+import {
+  enumArraySchema,
+  generateObjSchema,
+} from '../util/schemas';
+
+const warningMessage = 'The disabled prop removes the element from being detected by screen readers.';
+
+const DEFAULT_ELEMENTS = [
+  'button',
+  'command',
+  'fieldset',
+  'keygen',
+  'optgroup',
+  'option',
+  'select',
+  'textarea',
+  'input',
+];
+
+const schema = generateObjSchema({
+  disabable: enumArraySchema(DEFAULT_ELEMENTS)
+    .filter((name) => DEFAULT_ELEMENTS.includes(name)),
+});
+
+export default {
+  meta: {
+    type: 'suggestion',
+    docs: {
+      recommended: false,
+      url: 'https://github.com/jsx-eslint/eslint-plugin-jsx-a11y/tree/HEAD/docs/rules/no-disabled.md',
+    },
+    schema: [schema],
+  },
+
+  create: (context) => ({
+    JSXAttribute: (attribute) => {
+      const disabable = (
+        context.options && context.options[0] && context.options[0].disabable
+      ) || DEFAULT_ELEMENTS;
+      // Only monitor eligible elements for "disabled".
+      const type = elementType(attribute.parent);
+      if (!disabable.includes(type)) {
+        return;
+      }
+
+      if (propName(attribute) === 'disabled') {
+        context.report({
+          node: attribute,
+          message: warningMessage,
+        });
+      }
+    },
+  }),
+};