I think it's related to MPE and pitch bends, but when creating a new project, and adding surge xt, then reopening the project. Surge XT will be pitched 2 semitones too low.
I suspect the VST3 pitchbend value is set to 0 when it should be set to 0.5, maybe because of #1350
Investigating at the Surge XT repo I found out that FL Studio sends a pitchbend value: surge-synthesizer/surge#854 when loading vst3 plugins, maybe radium could do the same after loading the plugin?