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lines changed Original file line number Diff line number Diff line change 11![ alt text] ( docs/Logo1.png " PyBioNetFit ")
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3- This application is for fitting BNGL and SBML models with metaheuristic methods.
3+ PyBioNetFit (PyBNF) is a general-purpose program for parameterizing biological models specified using the BioNetGen
4+ rule-based modeling language (BNGL) or the Systems Biology Markup Language (SBML). PyBioNetFit offers a suite of
5+ parallelized metaheuristic algorithms (differential evolution, particle swarm optimization, scatter search) for
6+ parameter optimization. In addition to model parameterization, PyBNF supports uncertainty quantification by
7+ bootstrapping or Bayesian approaches, and model checking. PyBNF includes the Biological Property Specification Language
8+ (BPSL) for defining qualitative data for use in parameterization or checking. It runs on most Linux and macOS
9+ workstations as well on computing clusters.
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511For documentation, refer to [ Documentation.pdf] ( Documentation.pdf ) or the online documentation at < https://pybnf.readthedocs.io/en/latest/ > .
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