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README.md

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![alt text](docs/Logo1.png "PyBioNetFit")
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This application is for fitting BNGL and SBML models with metaheuristic methods.
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PyBioNetFit (PyBNF) is a general-purpose program for parameterizing biological models specified using the BioNetGen
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rule-based modeling language (BNGL) or the Systems Biology Markup Language (SBML). PyBioNetFit offers a suite of
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parallelized metaheuristic algorithms (differential evolution, particle swarm optimization, scatter search) for
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parameter optimization. In addition to model parameterization, PyBNF supports uncertainty quantification by
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bootstrapping or Bayesian approaches, and model checking. PyBNF includes the Biological Property Specification Language
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(BPSL) for defining qualitative data for use in parameterization or checking. It runs on most Linux and macOS
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workstations as well on computing clusters.
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For documentation, refer to [Documentation.pdf](Documentation.pdf) or the online documentation at <https://pybnf.readthedocs.io/en/latest/>.
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