We like to show how to integrate Custodia with existing secrets storage solution such as HashiCorp Vault or other solutions a mentioned at https://medium.com/on-docker/secrets-and-lie-abilities-the-state-of-modern-secret-management-2017-c82ec9136a3d . Vault from HashiCorp is one of the well-known and established backends.
You can use https://github.com/latchset/custodia.ipa as a template for a HC Vault plugin.