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| 1 | +package org.mastodon.mamut.tomancak.lineage_registration; |
| 2 | + |
| 3 | +import java.io.IOException; |
| 4 | +import java.util.ArrayList; |
| 5 | +import java.util.Arrays; |
| 6 | +import java.util.HashMap; |
| 7 | +import java.util.List; |
| 8 | +import java.util.Map; |
| 9 | +import java.util.stream.Collectors; |
| 10 | +import java.util.stream.IntStream; |
| 11 | + |
| 12 | +import org.apache.commons.lang3.tuple.Pair; |
| 13 | +import org.mastodon.collection.RefIntMap; |
| 14 | +import org.mastodon.collection.RefRefMap; |
| 15 | +import org.mastodon.collection.ref.RefIntHashMap; |
| 16 | +import org.mastodon.mamut.ProjectModel; |
| 17 | +import org.mastodon.mamut.io.ProjectLoader; |
| 18 | +import org.mastodon.mamut.model.Link; |
| 19 | +import org.mastodon.mamut.model.Model; |
| 20 | +import org.mastodon.mamut.model.Spot; |
| 21 | +import org.mastodon.mamut.tomancak.lineage_registration.spatial_registration.SpatialRegistrationMethod; |
| 22 | +import org.mastodon.mamut.views.trackscheme.MamutBranchViewTrackScheme; |
| 23 | +import org.mastodon.model.tag.ObjTagMap; |
| 24 | +import org.mastodon.model.tag.TagSetStructure; |
| 25 | +import org.mastodon.util.TagSetUtils; |
| 26 | +import org.scijava.Context; |
| 27 | + |
| 28 | +import mpicbg.spim.data.SpimDataException; |
| 29 | + |
| 30 | +/** |
| 31 | + * Do pairwise {@link LineageRegistrationAlgorithm lineage registration} of multiple embryos. |
| 32 | + * Tag the cells that are uniquely identified by the registration, without contradiction. |
| 33 | + */ |
| 34 | +public class MultiEmbryoRegistration |
| 35 | +{ |
| 36 | + public static void main( final String... args ) |
| 37 | + { |
| 38 | + final List< String > projectPaths = Arrays.asList( |
| 39 | + "/home/arzt/Datasets/Mette/E1.mastodon", |
| 40 | + "/home/arzt/Datasets/Mette/E2.mastodon", |
| 41 | + "/home/arzt/Datasets/Mette/E3.mastodon" |
| 42 | + ); |
| 43 | + try (final Context context = new Context()) |
| 44 | + { |
| 45 | + final List< ProjectModel > projectModels = projectPaths.stream().map( path -> { |
| 46 | + try |
| 47 | + { |
| 48 | + return ProjectLoader.open( path, context, false, true ); |
| 49 | + } |
| 50 | + catch ( IOException | SpimDataException e ) |
| 51 | + { |
| 52 | + throw new RuntimeException( e ); |
| 53 | + } |
| 54 | + } ).collect( Collectors.toList() ); |
| 55 | + final List< Model > models = projectModels.stream().map( ProjectModel::getModel ).collect( Collectors.toList() ); |
| 56 | + // FIXME: models.forEach( model -> ImproveAnglesDemo.removeBackEdges( model.getGraph() ) ); |
| 57 | + createTags( models.get( 0 ), computeAgreement( models ) ); |
| 58 | + projectModels.get( 0 ).getWindowManager().createView( MamutBranchViewTrackScheme.class ); |
| 59 | + } |
| 60 | + } |
| 61 | + |
| 62 | + private static RefIntMap< Spot > computeAgreement( final List< Model > models ) |
| 63 | + { |
| 64 | + final Map< Pair< Model, Model >, RefRefMap< Spot, Spot > > registrations = new HashMap<>(); |
| 65 | + for ( final Pair< Model, Model > pair : makePairs( models ) ) |
| 66 | + registrations.put( pair, register( pair.getLeft(), pair.getRight() ) ); |
| 67 | + |
| 68 | + final Model firstModel = models.get( 0 ); |
| 69 | + final RefIntMap< Spot > agreement = new RefIntHashMap<>( firstModel.getGraph().vertices().getRefPool(), 0 ); |
| 70 | + |
| 71 | + final List< Model > otherModels = models.subList( 1, models.size() ); |
| 72 | + for ( final Pair< Model, Model > pair : makePairs( otherModels ) ) |
| 73 | + { |
| 74 | + final Model otherModelA = pair.getLeft(); |
| 75 | + final Model otherModelB = pair.getRight(); |
| 76 | + final RefRefMap< Spot, Spot > registrationA = registrations.get( Pair.of( firstModel, otherModelA ) ); |
| 77 | + final RefRefMap< Spot, Spot > registrationB = registrations.get( Pair.of( firstModel, otherModelB ) ); |
| 78 | + final RefRefMap< Spot, Spot > registrationAB = registrations.get( pair ); |
| 79 | + incrementAgreement( agreement, registrationA, registrationB, registrationAB ); |
| 80 | + } |
| 81 | + |
| 82 | + return agreement; |
| 83 | + } |
| 84 | + |
| 85 | + private static void incrementAgreement( final RefIntMap< Spot > agreement, final RefRefMap< Spot, Spot > registrationA, final RefRefMap< Spot, Spot > registrationB, |
| 86 | + final RefRefMap< Spot, Spot > registrationAB ) |
| 87 | + { |
| 88 | + final Spot refA = registrationA.createValueRef(); |
| 89 | + final Spot refB = registrationB.createValueRef(); |
| 90 | + final Spot refB2 = registrationAB.createValueRef(); |
| 91 | + for ( final Spot key : registrationA.keySet() ) |
| 92 | + if ( registrationB.containsKey( key ) ) |
| 93 | + { |
| 94 | + final Spot spotA = registrationA.get( key, refA ); |
| 95 | + final Spot spotB = registrationB.get( key, refB ); |
| 96 | + final Spot crossSpotB = registrationAB.get( spotA, refB2 ); |
| 97 | + final boolean correct = spotB.equals( crossSpotB ); |
| 98 | + if ( correct ) |
| 99 | + agreement.put( key, agreement.get( key ) + 1 ); |
| 100 | + } |
| 101 | + } |
| 102 | + |
| 103 | + private static RefRefMap< Spot, Spot > register( final Model firstModel, final Model otherModel ) |
| 104 | + { |
| 105 | + return LineageRegistrationAlgorithm.run( firstModel, 0, otherModel, 0, SpatialRegistrationMethod.DYNAMIC_ROOTS ).mapAB; |
| 106 | + } |
| 107 | + |
| 108 | + private static List< Pair< Model, Model > > makePairs( final List< Model > otherModels ) |
| 109 | + { |
| 110 | + final List< Pair< Model, Model > > spokes = new ArrayList<>(); |
| 111 | + for ( int i = 0; i < otherModels.size(); i++ ) |
| 112 | + for ( int j = i + 1; j < otherModels.size(); j++ ) |
| 113 | + spokes.add( Pair.of( otherModels.get( i ), otherModels.get( j ) ) ); |
| 114 | + return spokes; |
| 115 | + } |
| 116 | + |
| 117 | + private static void createTags( final Model firstModel, final RefIntMap< Spot > agreement ) |
| 118 | + { |
| 119 | + int max = 0; |
| 120 | + for ( final Spot spot : agreement.keySet() ) |
| 121 | + max = Math.max( max, agreement.get( spot ) ); |
| 122 | + final List< Pair< String, Integer > > correct = |
| 123 | + IntStream.rangeClosed( 0, max ).mapToObj( i -> Pair.of( String.valueOf( i ), Glasbey.GLASBEY[ i + 1 ] ) ).collect( Collectors.toList() ); |
| 124 | + |
| 125 | + final TagSetStructure.TagSet tagSet = TagSetUtils.addNewTagSetToModel( firstModel, "UnifiedEmbryo", correct ); |
| 126 | + final List< TagSetStructure.Tag > tags = tagSet.getTags(); |
| 127 | + final ObjTagMap< Link, TagSetStructure.Tag > edgeTags = firstModel.getTagSetModel().getEdgeTags().tags( tagSet ); |
| 128 | + for ( final Spot spot : agreement.keySet() ) |
| 129 | + { |
| 130 | + final int value = agreement.get( spot ); |
| 131 | + final TagSetStructure.Tag tag = tags.get( max - value ); |
| 132 | + TagSetUtils.tagBranch( firstModel, tagSet, tag, spot ); |
| 133 | + if ( spot.incomingEdges().size() == 1 ) |
| 134 | + { |
| 135 | + final Link link = spot.incomingEdges().iterator().next(); |
| 136 | + edgeTags.set( link, tag ); |
| 137 | + } |
| 138 | + } |
| 139 | + } |
| 140 | +} |
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