Description of feature
Add an opt-in parameter to use host-filtered or host-depleted FASTQ files for downstream mapping and polishing steps when those files are available.
See original proposal in #280
Current behavior
Downstream steps such as sspace_basic, bwamem2, and bowtie2 currently use the original clean FASTQ files. This preserves current behavior, but it can increase runtime and storage usage substantially on large datasets.
Proposal
- Add a new pipeline parameter, defaulting to
false.
- When enabled, prefer host-filtered reads for downstream mapping and polishing steps after host subtraction has completed successfully.
- Keep the current clean-read behavior as the default for backwards compatibility.
- Update tests and documentation accordingly.
Description of feature
Add an opt-in parameter to use host-filtered or host-depleted FASTQ files for downstream mapping and polishing steps when those files are available.
See original proposal in #280
Current behavior
Downstream steps such as
sspace_basic,bwamem2, andbowtie2currently use the original clean FASTQ files. This preserves current behavior, but it can increase runtime and storage usage substantially on large datasets.Proposal
false.