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NIBS-BIDS (BEP037)

The NIBS-BIDS repository contains supporting files for the NIBS-BIDS extension proposal.

Mock experiments for NIBS-BIDS examples

Below are some basic TMS experiments to test the current NIBS-BIDS framework. Outcome data files are described which should be converted into BIDS format for a single participant (sub001). Hardware and pulse shape are dealers choice.

1. Online motor TMS-EMG experiment

TMS applied during EMG recording. No neuronavigation.

  • Resting motor threshold (no recorded data)
  • Active motor threshold (no recorded data)
  • Intensity required for MEP of 1 mV (no recorded data)
  • Single pulse MEPs (input-output curve) - 10 trials at 90%, 100%, 110% and 120% RMT, interleaved
  • SICI (2 ms ISI) - 10 trials single pulse, 10 trials paired pulse, interleaved. Conditioning pulse = 80% AMT, Test pulse = S1mV.

2. Online prefrontal TMS-EEG experiment

TMS applied to prefrontal cortex during EEG recording. Coil position recorded using neuronavigation with each trial.

  • Resting motor threshold (no recorded data)
  • Single pulse TEPs (120% RMT) - 100 trials

3. Offline prefrontal iTBS experiment

iTBS applied to prefrontal cortex. Working memory performance (no neural recordings) assessed before and after stimulation. Coil position recorded using neuronavigation.

  • Resting motor threshold (no recorded data)
  • Pre working memory task (beh file)
  • iTBS (70% RMT, 600 pulses, standard parameters)
  • Post working memory task (beh file)

4. (TMS-BIDS team): Multimodal TMS Experiment During Product Preference Decision-Making

In this neuro-marketing study, participants evaluate product preferences (Brand A vs Brand B) while undergoing brain stimulation. During the decision-making task, the following data are collected simultaneously:

  • EEG (to monitor cognitive responses),
  • fNIRS (to track prefrontal cortex activation),
  • Behavioral data — including response times and button presses,
  • TMS is applied to the dorsolateral prefrontal cortex (dlPFC) during evaluation phases to modulate decision-related activity.
  • Protocol: Single-pulse TMS
  • Target: dlPFC
  • Intensity: 110% of RMT
  • Total Pulses: 60 (10 pulses per block, 6 blocks total)
  • Neuronavigation: Yes, coil position recorded for each pulse

5. (TMS-BIDS team): Combined TMS Motor Study — Mixed Online/Offline Stimulation

This example demonstrates a realistic multi-session experiment combining both offline and online transcranial magnetic stimulation (TMS) protocols targeting the motor cortex and parietal regions.

  • Three lab visits on separate days
  • Day 1 cTBS over inferior parietal cortex
  • Day 2 cTBS over M1
  • Day 3 Sham cTBS
  • Within each day
  • Block A SICI, ICF, single-pulse (SP) baseline with EMG MEPs
  • Block B Action-observation task with single-pulse TMS during video observation, EMG MEPs recorded
  • Block C SICI, ICF, SP post

6. TMS-EMG plasticity study

  • Protocol
  • RMT
  • 10 trials single pulse MEP (EMG) - S1mV
  • iTBS (standard; 70% RMT)
  • 10 trials single pulse MEP (EMG) - S1mV

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