diff --git a/boot/zephyr/CMakeLists.txt b/boot/zephyr/CMakeLists.txt
index cfc9a243a..ce55effbb 100644
--- a/boot/zephyr/CMakeLists.txt
+++ b/boot/zephyr/CMakeLists.txt
@@ -491,6 +491,10 @@ zephyr_library_sources(
 )
 endif()
 
+if(CONFIG_SOC_NRF54H20_PM_S2RAM_OVERRIDE)
+  zephyr_library_sources(${BOOT_DIR}/zephyr/nrf54h20_custom_s2ram.c)
+endif()
+
 if(CONFIG_MCUBOOT_BOOT_BANNER)
   # Replace Zephyr's boot banner with the MCUboot one
   zephyr_sources(kernel/banner.c)
diff --git a/boot/zephyr/nrf54h20_custom_s2ram.c b/boot/zephyr/nrf54h20_custom_s2ram.c
new file mode 100644
index 000000000..7b70e22fe
--- /dev/null
+++ b/boot/zephyr/nrf54h20_custom_s2ram.c
@@ -0,0 +1,97 @@
+/*
+ * Copyright (c) 2025 Nordic Semiconductor ASA
+ * SPDX-License-Identifier: Apache-2.0
+ */
+
+#include <stdbool.h>
+#include <zephyr/arch/common/pm_s2ram.h>
+#include <hal/nrf_resetinfo.h>
+#include "pm_s2ram.h"
+#include "power.h"
+
+#include <zephyr/devicetree.h>
+#include <zephyr/storage/flash_map.h>
+
+#include "bootutil/fault_injection_hardening.h"
+
+#if DT_NODE_EXISTS(DT_NODELABEL(mcuboot_s2ram)) &&\
+    DT_NODE_HAS_COMPAT(DT_NODELABEL(mcuboot_s2ram), zephyr_memory_region)
+/* Linker section name is given by `zephyr,memory-region` property of
+ * `zephyr,memory-region` compatible DT node with nodelabel `mcuboot_s2ram`.
+ */
+__attribute__((section(DT_PROP(DT_NODELABEL(mcuboot_s2ram), zephyr_memory_region))))
+volatile struct mcuboot_resume_s mcuboot_resume;
+#else
+#error  "mcuboot resume support section not defined in dts"
+#endif
+
+#define FIXED_PARTITION_ADDR(node_label)                                   \
+    (DT_REG_ADDR(DT_NODELABEL(node_label)) +                               \
+     COND_CODE_0(DT_FIXED_PARTITION_EXISTS(DT_NODELABEL(node_label)), (0), \
+        (DT_REG_ADDR(DT_GPARENT(DT_NODELABEL(node_label))))))
+
+
+int soc_s2ram_suspend(pm_s2ram_system_off_fn_t system_off)
+{
+    (void)(system_off);
+    return -1;
+}
+
+void pm_s2ram_mark_set(void)
+{
+    /* empty */
+}
+
+struct arm_vector_table {
+    uint32_t msp;
+    uint32_t reset;
+};
+
+/* This could be read from slot's image_header.ih_hdr_size, but immediate value
+ * is much faster to reach
+ */
+#define APP_EXE_START_OFFSET 0x800 /* nRF54H20 */
+
+bool pm_s2ram_mark_check_and_clear(void)
+{
+    uint32_t reset_reason = nrf_resetinfo_resetreas_local_get(NRF_RESETINFO);
+
+    if (reset_reason != NRF_RESETINFO_RESETREAS_LOCAL_UNRETAINED_MASK) {
+        /* Normal boot */
+        return false;
+    }
+
+    /* S2RAM resume expected, do doublecheck */
+    if (mcuboot_resume.magic == MCUBOOT_S2RAM_RESUME_MAGIC) {
+        /* clear magic to avoid accidental reuse */
+        mcuboot_resume.magic = 0;
+    } else {
+        /* magic not valid, normal boot */
+        goto resume_failed;
+    }
+
+    /* s2ram boot */
+    struct arm_vector_table *vt;
+    vt = (struct arm_vector_table *)
+            (FIXED_PARTITION_ADDR(slot0_partition) + APP_EXE_START_OFFSET);
+
+    /* Jump to application */
+    __asm__ volatile (
+        /* vt->reset -> r0 */
+        "   mov     r0, %0\n"
+        /* vt->msp -> r1 */
+        "   mov     r1, %1\n"
+        /* set stack pointer */
+        "   msr     msp, r1\n"
+        /* jump to reset vector of an app */
+        "   bx      r0\n"
+        :
+        : "r" (vt->reset), "r" (vt->msp)
+        : "r0", "r1", "memory"
+    );
+
+resume_failed:
+    FIH_PANIC;
+
+    return true;
+}
diff --git a/boot/zephyr/socs/nrf54h20_cpuapp.conf b/boot/zephyr/socs/nrf54h20_cpuapp.conf
new file mode 100644
index 000000000..09ccb19b2
--- /dev/null
+++ b/boot/zephyr/socs/nrf54h20_cpuapp.conf
@@ -0,0 +1,13 @@
+# Copyright (c) 2025 Nordic Semiconductor ASA
+#
+# SPDX-License-Identifier: Apache-2.0
+#
+
+# Configuration which is needed for supporting resume the application execution
+# after suspend to RAM (S2RAM) requested by the application.
+# MCUboot does not support S2RAM itself, but serves as an immediate actor while waking up
+# from suspension.
+CONFIG_PM=y
+CONFIG_PM_S2RAM=y
+CONFIG_PM_S2RAM_CUSTOM_MARKING=y
+CONFIG_SOC_NRF54H20_PM_S2RAM_OVERRIDE=y