From bb6b52cbbaec52227e3d4c4a35485cd251bf708e Mon Sep 17 00:00:00 2001 From: RiveraAndrea83 Date: Tue, 17 Mar 2026 13:12:56 +0000 Subject: [PATCH] release files --- cl-base.owl | 5703 +++- cl.obo | 7673 ++--- src/ontology/reports/cl-base-diff.md | 9717 +++++- .../reports/cl-edit.owl-obo-report.tsv | 5 +- src/ontology/reports/release-diff.md | 26856 ++++++++++++++-- src/ontology/reports/summary_release.md | 1183 +- .../subsets/blood_and_immune_upper_slim.json | 4381 ++- .../subsets/blood_and_immune_upper_slim.obo | 101 +- .../subsets/blood_and_immune_upper_slim.owl | 778 +- .../subsets/blood_and_immune_upper_slim.tsv | 7 +- src/ontology/subsets/eye_upper_slim.json | 5494 +++- src/ontology/subsets/eye_upper_slim.obo | 206 +- src/ontology/subsets/eye_upper_slim.owl | 1699 +- src/ontology/subsets/eye_upper_slim.tsv | 19 +- .../general_cell_types_upper_slim.json | 4025 ++- .../subsets/general_cell_types_upper_slim.obo | 185 +- .../subsets/general_cell_types_upper_slim.owl | 1103 +- .../subsets/general_cell_types_upper_slim.tsv | 18 +- src/ontology/subsets/kidney_upper_slim.json | 4865 ++- src/ontology/subsets/kidney_upper_slim.obo | 126 +- src/ontology/subsets/kidney_upper_slim.owl | 1314 +- src/ontology/subsets/kidney_upper_slim.tsv | 9 +- subsets/blood_and_immune_upper_slim.json | 4381 ++- subsets/blood_and_immune_upper_slim.obo | 101 +- subsets/blood_and_immune_upper_slim.owl | 778 +- subsets/blood_and_immune_upper_slim.tsv | 7 +- subsets/eye_upper_slim.json | 5494 +++- subsets/eye_upper_slim.obo | 206 +- subsets/eye_upper_slim.owl | 1699 +- subsets/eye_upper_slim.tsv | 19 +- subsets/general_cell_types_upper_slim.json | 4025 ++- subsets/general_cell_types_upper_slim.obo | 185 +- subsets/general_cell_types_upper_slim.owl | 1103 +- subsets/general_cell_types_upper_slim.tsv | 18 +- subsets/kidney_upper_slim.json | 4865 ++- subsets/kidney_upper_slim.obo | 126 +- subsets/kidney_upper_slim.owl | 1314 +- subsets/kidney_upper_slim.tsv | 9 +- 38 files changed, 81564 insertions(+), 18233 deletions(-) diff --git a/cl-base.owl b/cl-base.owl index af00a3364..854debb87 100644 --- a/cl-base.owl +++ b/cl-base.owl @@ -24,7 +24,7 @@ xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#" xmlns:CCN20230722="https://purl.brain-bican.org/taxonomy/CCN20230722#"> - + An ontology of cell types. Cell Ontology @@ -40,7 +40,7 @@ See PMID:15693950, PMID:12799354, PMID:20123131, PMID:21208450; Contact Alexander Diehl, addiehl[at]buffalo.edu, university at buffalo. - 2025-12-17 + 2026-03-17 @@ -122,12 +122,6 @@ - - - - - - @@ -744,6 +738,18 @@ + + + + + + + + + + + + @@ -2365,6 +2371,7 @@ The process of fertilization occurs when one sperm cell successfully penetrates + @@ -2419,6 +2426,7 @@ When glioblast multiplication is dysregulated, it can lead to harmful manifestat + @@ -2519,14 +2527,7 @@ When glioblast multiplication is dysregulated, it can lead to harmful manifestat - - - - - - - @@ -2543,11 +2544,10 @@ Stem cells have numerous potential applications in medicine, including the treat CALOHA:TS-2086 FMA:63368 ZFA:0005957 - animal stem cell + animal stem cell - This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. stem cell https://cellxgene.cziscience.com/cellguide/CL_0000034 stem cell @@ -2672,6 +2672,7 @@ Single fate stem cells play a crucial role in the body's diverse tissues by + @@ -2787,6 +2788,7 @@ Furthermore, these cells serve a critical role in cellular differentiation, wher + @@ -4678,9 +4680,11 @@ Ependymal cells form a barrier between the cerebrospinal fluid and the adjacent An epithelial cell that has a cilia. + FMA:70605 ZFA:0009035 + ciliated epithelial cell ciliated epithelial cell @@ -4924,7 +4928,26 @@ Blood vessel endothelial cells are sensitive to various stimuli, including shear + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -5054,8 +5077,25 @@ These cells have adaptive capabilities that facilitate their role in many pathol + + + + + + + + + + + + + + + + + @@ -9785,6 +9825,40 @@ Impaired function of the type B cells is associated with type 1 and type 2 diabe https://cellxgene.cziscience.com/cellguide/CL_0000169 https://cdn.humanatlas.io/digital-objects/2d-ftu/pancreas-islets-langerhans/v1.2/assets/2d-ftu-pancreas-islets-langerhans.png + + + + + true + + + + + A cell that secretes insulin and is located towards the center of the islets of Langerhans. + GOC:tfm + ISBN:0517223651 + http://en.wikipedia.org/wiki/Pancreatic_b_cell + + + + + Type B pancreatic cells, also known as beta cells, are one of the endocrine cell types located in the pancreas. They represent 70-80% of the cells in the islets of Langerhans, the endocrine part of this organ. Unique to mammals, Type B pancreatic cells are the predominant cell type in the pancreatic islets (50–80% of all islet endocrine cells) and play a crucial role in the body's metabolic regulation and glucose homeostasis. +The primary function of type B pancreatic cells is the production, storage, and release of insulin, accounting for almost all insulin production in the human body: each cell contains about 20 pg insulin. Insulin has a critical function in regulating blood sugar levels: whenever glucose levels in the blood are high, such as after a meal, type B pancreatic cells secrete insulin to promote glucose uptake into cells, transforming it into usable energy or storing it for later use. Additionally, insulin also inhibits glucose production by the liver, therefore lowering blood glucose levels. +Impaired function of the type B cells is associated with type 1 and type 2 diabetes, metabolic diseases characterized by chronic hyperglycemia. In type 1 diabetes, an autoimmune response leads to the attack of the body’s own type B cells, resulting in the insufficient production and secretion of insulin. In type 2 diabetes, insulin resistance occurs, and type B cells are unable to compensate by producing more insulin. + +(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) + DOI:10.1007/s40828-021-00140-3 + DOI:10.1038/s41574-020-00443-4 + DOI:10.1155/2017/1478294 + DOI:10.3389/fcell.2017.00055 + DOI:10.3390/ijms22126403 + + + + + beta cell + ZFA:0009102 + @@ -9852,40 +9926,6 @@ Impaired function of the type B cells is associated with type 1 and type 2 diabe doi:10.48539/HBM637.SFSW.654 - - - - - true - - - - - A cell that secretes insulin and is located towards the center of the islets of Langerhans. - GOC:tfm - ISBN:0517223651 - http://en.wikipedia.org/wiki/Pancreatic_b_cell - - - - - Type B pancreatic cells, also known as beta cells, are one of the endocrine cell types located in the pancreas. They represent 70-80% of the cells in the islets of Langerhans, the endocrine part of this organ. Unique to mammals, Type B pancreatic cells are the predominant cell type in the pancreatic islets (50–80% of all islet endocrine cells) and play a crucial role in the body's metabolic regulation and glucose homeostasis. -The primary function of type B pancreatic cells is the production, storage, and release of insulin, accounting for almost all insulin production in the human body: each cell contains about 20 pg insulin. Insulin has a critical function in regulating blood sugar levels: whenever glucose levels in the blood are high, such as after a meal, type B pancreatic cells secrete insulin to promote glucose uptake into cells, transforming it into usable energy or storing it for later use. Additionally, insulin also inhibits glucose production by the liver, therefore lowering blood glucose levels. -Impaired function of the type B cells is associated with type 1 and type 2 diabetes, metabolic diseases characterized by chronic hyperglycemia. In type 1 diabetes, an autoimmune response leads to the attack of the body’s own type B cells, resulting in the insufficient production and secretion of insulin. In type 2 diabetes, insulin resistance occurs, and type B cells are unable to compensate by producing more insulin. - -(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) - DOI:10.1007/s40828-021-00140-3 - DOI:10.1038/s41574-020-00443-4 - DOI:10.1155/2017/1478294 - DOI:10.3389/fcell.2017.00055 - DOI:10.3390/ijms22126403 - - - - - beta cell - ZFA:0009102 - @@ -10603,6 +10643,7 @@ Alterations in hepatocyte function have significant implications for overall hum Contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament. + BTO:0002309 CALOHA:TS-2379 FMA:67799 @@ -10610,6 +10651,7 @@ Alterations in hepatocyte function have significant implications for overall hum basket epithelial cell myoepitheliocyte + myoepithelial cell @@ -10701,6 +10743,7 @@ However, while myofibroblasts play a critical role in normal wound healing, thei A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -10712,6 +10755,7 @@ However, while myofibroblasts play a critical role in normal wound healing, thei myocyte + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -11307,26 +11351,20 @@ On a cellular level, smooth muscle cells possess a single, centrally located nuc - + - - - - - - - Any neuronal receptor cell that is capable of some detection of mechanical stimulus involved in sensory perception of gravity. + Any neuronal receptor cell that is capable of some detection of mechanical stimulus involved in sensory perception. gravity sensitive cell - Any neuronal receptor cell that is capable of some detection of mechanical stimulus involved in sensory perception of gravity. + Any neuronal receptor cell that is capable of some detection of mechanical stimulus involved in sensory perception. FBC:Autogenerated @@ -12696,7 +12734,7 @@ Tissue-resident macrophages are diverse and heterogenous, likely as a result of - + @@ -12766,19 +12804,17 @@ Tissue-resident macrophages are diverse and heterogenous, likely as a result of - + + + + + - - - - - - A stratified epithelial cell that is part of squamous epithelium, characterized by multiple layers of cells. The basal layer is directly attached to the basement membrane and the apical layer consists of flattened squamous cells. This provides a protective barrier, commonly found in areas subject to abrasion, such as the skin, oral cavity, and esophagus. Stratified squamous epithelial cells are a specific type of epithelial cell that form layers and have a flat shape. These cells are part of the outermost layer of the skin, called the epidermis, and are also found lining surfaces of the body that are subjected to physical or chemical wear and tear, such as the mouth, esophagus, and vagina. The primary role of these cells is to create a barrier that protects underlying tissues from dehydration, abrasion, and infection. @@ -14703,6 +14739,7 @@ Gametes have a primary role in sexual reproduction and genetic variation, which + @@ -15965,6 +16002,7 @@ One notable characteristic of epidermal cells is their continuous cycle of renew + @@ -17495,20 +17533,20 @@ The function of male gametes does not cease upon fertilization. In addition to d - + A stem cell that gives rise to the follicle cells that surround the oocyte in female arthropods. somatic stem cell FBbt:00004903 follicle stem cell (sensu Arthropoda) - + - + https://github.com/obophenotype/cell-ontology/issues/1943 @@ -17688,6 +17726,7 @@ Because of their important role in antigen presentation and immune regulation, F + @@ -18759,7 +18798,7 @@ Additionally, the dendritic cells can influence the type of immune response the - + @@ -18772,14 +18811,14 @@ Additionally, the dendritic cells can influence the type of immune response the FBbt:00004904 follicle cell of egg chamber - + - + @@ -20463,19 +20502,19 @@ Functionally, smooth muscle myoblasts and the mature muscle cells they generate - + A neuron that develops during the early segmentation stages in teleosts, before the neural tube is formed. ZFA:0009242 primary neuron (sensu Teleostei) - + - + https://github.com/obophenotype/cell-ontology/pull/1950 @@ -20624,19 +20663,19 @@ Functionally, smooth muscle myoblasts and the mature muscle cells they generate - + A neuron of teleosts that develops later than a primary neuron, typically during the larval stages. ZFA:0009246 secondary neuron (sensu Teleostei) - + - + https://github.com/obophenotype/cell-ontology/pull/1950 @@ -20797,6 +20836,7 @@ Functionally, smooth muscle myoblasts and the mature muscle cells they generate + @@ -26630,6 +26670,7 @@ HSCs become highly active when the liver is damaged or diseased. They play a cru + A cuboidal cell which along with Boettcher's cells form the floor of the external spiral sulcus, external to the organ of Corti. FMA:79802 cell of Claudius @@ -28344,6 +28385,7 @@ Furthermore, pericytes have demonstrated functions in regulating immune and infl + @@ -29879,6 +29921,7 @@ Somatic stem cells respond to environmental signals that regulate their quiescen + @@ -30112,6 +30155,7 @@ Beyond their mechanical function, urothelial cells also play a role in sensing a MESH:D007962 NCIT:C12529 ZFA:0009309 + WBC leucocyte white blood cell immune cell @@ -30139,6 +30183,13 @@ Beyond their mechanical function, urothelial cells also play a role in sensing a ZFA:0009309 + + + + WBC + PMID:40794848 + + @@ -30650,6 +30701,7 @@ At the functional level, retinal bipolar neurons can be categorized into ON and retinal bipolar neuron + https://cellxgene.cziscience.com/cellguide/CL_0000748 @@ -30701,6 +30753,12 @@ At the functional level, retinal bipolar neurons can be categorized into ON and + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -30810,6 +30868,7 @@ Bearing intricate dendritic trees, these cells can integrate responses from mult The marker set CDHR3, PRKCA-AS1 can identify the Human cell type http://purl.obolibrary.org/obo/CL_0000751 in the retina with a confidence of 0.929575519 (NS-Forest FBeta value). The marker set ENSG00000227681, C16orf74 can identify the Human cell type http://purl.obolibrary.org/obo/CL_0000751 in the retina with a confidence of 0.907779697 (NS-Forest FBeta value). rod bipolar cell + https://cellxgene.cziscience.com/cellguide/CL_0000751 @@ -30857,6 +30916,12 @@ Bearing intricate dendritic trees, these cells can integrate responses from mult The marker set ENSG00000227681, C16orf74 can identify the Human cell type http://purl.obolibrary.org/obo/CL_0000751 in the retina with a confidence of 0.907779697 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -30961,7 +31026,7 @@ Bearing intricate dendritic trees, these cells can integrate responses from mult - + @@ -30992,7 +31057,7 @@ Bearing intricate dendritic trees, these cells can integrate responses from mult type 2 cone bipolar cell (sensu Mus) - + @@ -31012,7 +31077,7 @@ Bearing intricate dendritic trees, these cells can integrate responses from mult - + PMID:27565351 @@ -33978,7 +34043,7 @@ With a majority of pathogens entering the body through the epithelial surfaces l - + A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. IEL intraepithelial lymphocyte @@ -34258,7 +34323,7 @@ These phenotypically different mature γδ T-cells are functionally versatile. I - + A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses. Gamma-delta intraepithelial T cells, also known as γδ intraepithelial lymphocytes (IELs), are a unique subset of T cells residing in the epithelial layer of mucosal tissues such as the intestine and skin; more are found in intestinal intraepithelial tissue than in other tissues. They are characterized by their distinct T-cell receptor (TCR) that is composed of one gamma (γ) and one delta (δ) chain, unlike the conventional alpha-beta T cells. Most γδ IELs also express the CD8-alpha-alpha homodimer (Cd8-alpha alpha positive, gamma-delta intraepithelial T cells), although some are lacking both co-receptors CD4 and CD8 (CD4-negative CD8-negative gamma-delta intraepithelial T cells). γδ IELs are though to be ‘natural’ IELs as they acquire their activated phenotype in an ‘alternative’ self-antigen-based maturation process in the thymus. Although the function of γδ IELs is still not fully established, current evidence indicates that they serve as a crucial first line of defense against invading pathogens, thus making them an important class of immune cells at the epithelial barrier interfaces. γδ IELs respond to a variety of antigens, including those not recognized by conventional T cells. They are also thought to be involved in recruiting in immune surveillance by promoting homeostasis of host microbiota and in limiting excessive inflammation. @@ -38171,7 +38236,7 @@ In addition to antibody-mediated responses, NK T cells are capable of cytotoxic - + @@ -41989,6 +42054,7 @@ However, dysfunction of M2 macrophages can be harmful. Alternatively activated m A effector T cell that provides help in the form of secreted cytokines to other immune cells. + BTO:0002417 MESH:D006377 T-helper cell @@ -41996,6 +42062,7 @@ However, dysfunction of M2 macrophages can be harmful. Alternatively activated m helper T-cell helper T-lymphocyte + helper T cell @@ -42120,13 +42187,11 @@ However, dysfunction of M2 macrophages can be harmful. Alternatively activated m An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers. - immature NK T lymphocyte immature NK T-cell immature NK T-lymphocyte immature NKT cell - immature NK T cell @@ -42692,7 +42757,7 @@ CD8αα IELs have been shown require β2 microglobulin-dependent MHC class I exp - + @@ -42701,7 +42766,7 @@ CD8αα IELs have been shown require β2 microglobulin-dependent MHC class I exp - + An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d. @@ -51371,6 +51436,10 @@ A remarkable aspect of osteocytes is their ability to perceive mechanical forces + + + + @@ -51384,7 +51453,13 @@ A remarkable aspect of osteocytes is their ability to perceive mechanical forces - A myeloid dendritic cell with the phenotype HLA-DRA-positive. + + + + + + + A myeloid dendritic cell with the phenotype HLA-DRA-positive and CD14-negative. myeloid dendritic cell This cell type is compatible with the HIPC Lyoplate markers for 'myeloid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human myeloid dendritic cells. @@ -51393,9 +51468,14 @@ A remarkable aspect of osteocytes is their ability to perceive mechanical forces - A myeloid dendritic cell with the phenotype HLA-DRA-positive. + A myeloid dendritic cell with the phenotype HLA-DRA-positive and CD14-negative. GOC:add PMID:22343568 + PMID:34260151 + PMID:36470845 + PMID:37254600 + PMID:38343094 + PMID:40095400 @@ -51417,6 +51497,10 @@ A remarkable aspect of osteocytes is their ability to perceive mechanical forces + + + + @@ -51440,13 +51524,19 @@ A remarkable aspect of osteocytes is their ability to perceive mechanical forces + + + + + + - A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, and CD11c-negative. + A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, CD11c-negative, and CD14-negative. plasmacytoid dendritic cell @@ -51457,9 +51547,14 @@ A remarkable aspect of osteocytes is their ability to perceive mechanical forces - A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, and CD11c-negative. + A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, CD11c-negative, and CD14-negative. GOC:add PMID:22343568 + PMID:34260151 + PMID:36470845 + PMID:37254600 + PMID:38343094 + PMID:40095400 @@ -53359,14 +53454,6 @@ The ILC precursors develop from the fetal liver and the adult bone marrow and, d - - - - - - - - @@ -53401,19 +53488,7 @@ The ILC precursors develop from the fetal liver and the adult bone marrow and, d - - - - - - - - - - - - - A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. + A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative. CD8-positive, alpha-beta memory T lymphocyte, CD45RO-positive CD8-positive, alpha-beta memory T-cell, CD45RO-positive @@ -53431,10 +53506,12 @@ The ILC precursors develop from the fetal liver and the adult bone marrow and, d - A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. + A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative. GOC:tfm GO_REF:0000031 PMID:20146720 + PMID:21926977 + PMID:24258910 @@ -53466,14 +53543,6 @@ The ILC precursors develop from the fetal liver and the adult bone marrow and, d - - - - - - - - @@ -53508,19 +53577,7 @@ The ILC precursors develop from the fetal liver and the adult bone marrow and, d - - - - - - - - - - - - - CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. + CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative. CD4-positive, alpha-beta memory T lymphocyte, CD45RO-positive CD4-positive, alpha-beta memory T-cell, CD45RO-positive CD4-positive, alpha-beta memory T-lymphocyte, CD45RO-positive @@ -53535,11 +53592,13 @@ The ILC precursors develop from the fetal liver and the adult bone marrow and, d - CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. + CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative. GOC:add GOC:tfm GO_REF:0000031 ISBN:0781735149 + PMID:21926977 + PMID:24258910 http://www.immgen.org/index_content.html @@ -56500,6 +56559,8 @@ The main function of pre-conventional dendritic cells is to constantly replenish + + @@ -56524,12 +56585,6 @@ The main function of pre-conventional dendritic cells is to constantly replenish - - - - - - @@ -58736,8 +58791,12 @@ A unique critical feature of type I pneumocytes is their inability to divide and - - + + + + + + @@ -58746,10 +58805,8 @@ A unique critical feature of type I pneumocytes is their inability to divide and - - - + @@ -58758,14 +58815,14 @@ A unique critical feature of type I pneumocytes is their inability to divide and - - + + - - + + @@ -64083,6 +64140,7 @@ Changes and mutations in the formation and growth of basal cells of the epidermi + A flat keratinocyte immediately below the cornified layer. @@ -64286,6 +64344,7 @@ Neutrophilic myelocytes contribute significantly to the body's primary immu + @@ -64326,6 +64385,7 @@ Neutrophilic myelocytes contribute significantly to the body's primary immu + @@ -64623,6 +64683,7 @@ Neutrophilic myelocytes contribute significantly to the body's primary immu An epithelial cell found in various organs, including the gastrointestinal and respiratory tracts, characterized by a tuft of 120-140 blunt microvilli on its apical surface. This cell exhibits diverse functions depending on its location, which includes chemosensation, initiation of immune responses, contribution to mucociliary clearance, and defense against parasites. + Brush cells, also referred to as tuft cells or multivesicular cells, are a specialized type of epithelial cell mainly noted for their characteristic 'brush border' composed of microvilli. These cells reside in the epithelial lining of tissue organs such as the respiratory tract, gastrointestinal tract, and the bile ducts. The name derives from their distinct appearance under the microscope, which resembles a brush due to the dense layer of microvilli protruding into the lumen. A key function of brush cells is chemosensation: They express a variety of signaling molecules and receptors that enable them to detect specific chemical stimuli in the environment and act as sensory transducers. Many of these receptors are responsive to luminal content, which makes brush cells vital for regulating and coordinating appropriate physiological responses to changes in these substances. @@ -64637,6 +64698,7 @@ Recent research has also elucidated an important role for these cells in immunit multivesicular cell peculiar cell + tuft cell https://cellxgene.cziscience.com/cellguide/CL_0002204 @@ -65206,6 +65268,7 @@ Recent research also suggests that brush cells of the bronchus could potentially + A squamous cell that has keratin in the esophagus. @@ -65255,6 +65318,7 @@ Recent research also suggests that brush cells of the bronchus could potentially + A cell of the transparent layer of simple cuboidal epithelium over the anterior surface of the lens; transform into lens fiber(s). The anterior lens cells, also known as lens epithelial cells, are an integral part of the eye's structure and play a critical role in the organ's physiological functioning. They are situated in the anterior portion of the lens, precisely in the lens capsule, and stretch over the lens' frontal surface. @@ -68067,7 +68131,7 @@ L-cells also secrete peptide YY (PYY), which plays a pivotal role in controlling - + A synovial cell that is macrophage-like, characterized by surface ruffles or lamellipodia, plasma membrane invaginations and associated micropinocytotic vesicles, Golgi apparatus and little granular endoplasmic reticulum. 2010-09-13T03:39:17Z @@ -68076,14 +68140,14 @@ L-cells also secrete peptide YY (PYY), which plays a pivotal role in controlling Type A cells are usually round and located in the upper part of the synovial intima. type A synovial cell - + - + PMID:10770586 @@ -71814,7 +71878,7 @@ Functionally, myotubes play a critical role in the formation and development of - + @@ -71842,6 +71906,7 @@ Functionally, myotubes play a critical role in the formation and development of + @@ -73660,6 +73725,12 @@ These cells have been implicated in the progression of pancreatic cancer. Activa + + + + + + @@ -77295,7 +77366,7 @@ These cells are also the primary sources of progesterone, crucial for maintainin - + @@ -77308,7 +77379,7 @@ These cells are also the primary sources of progesterone, crucial for maintainin - + @@ -77317,8 +77388,9 @@ These cells are also the primary sources of progesterone, crucial for maintainin - A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. + A tissue-resident lymphocyte located within the epithelial layer of mucosal tissues, particularly within the gastrointestinal, respiratory, and reproductive tracts. Characterised by permanent residency, this cell typically expresses CD103 (integrin alpha-E), which binds to E-cadherin on epithelial cells, enabling epithelial retention in both mice and humans. Phenotypically, IEL displays an activated, antigen-experienced state characterised by the constitutive expression of cytotoxic molecules (granzyme B, perforin) and innate-like receptors (such as NKG2D), enabling rapid, localised surveillance and immediate response to epithelial stress. + Intraepithelial lymphocytes (IELs) are a large and diverse population of mainly T cells that reside within the epithelial cell layer of various mucosal tissues in the body, including the skin, intestine, and respiratory tract. These cells represent a substantial amount of the total lymphocyte pool and are most numerous in the intestine. They have distinct phenotypes and functional characteristics compared to lymphocytes residing in other tissues. Most intraepithelial lymphocytes express heterodimeric T-cell receptors (TCRs) consisting of αlpha and beta chains (TCRαβ), or less commonly gamma and delta chains (TCRγδ), together with the CD8 co-receptor (αβ or αα); there are also smaller subpopulations of IELs that areCD4+, or negative for both CD4 and CD8. Intraepithelial T cells typically express high levels of activation markers, tissue-homing integrins, and receptors and molecules characteristic of natural killer cells and cytotoxic T lymphocytes. TCRαβ+CD8+ IEL are able to recognize both transformed self antigens via natural killer receptors and foreign antigen via the TCR. The primary function of IELs is to maintain the integrity of mucosal barriers against pathogens. Given their strategic location within the epithelial layer, they are often the first immune cells that encounter invading infectious agents, such as bacteria, fungi, or viruses. Upon encountering pathogens, IELs activate and quickly respond by either directly killing the infected epithelial cells or alerting other immune cells. This rapid response, initiated by IELs, helps constrain the infection at the point of entry and is vital to maintaining the integrity of mucosal barriers. @@ -77343,9 +77415,11 @@ In addition to their central role in maintaining the integrity of epithelial bar - A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. + A tissue-resident lymphocyte located within the epithelial layer of mucosal tissues, particularly within the gastrointestinal, respiratory, and reproductive tracts. Characterised by permanent residency, this cell typically expresses CD103 (integrin alpha-E), which binds to E-cadherin on epithelial cells, enabling epithelial retention in both mice and humans. Phenotypically, IEL displays an activated, antigen-experienced state characterised by the constitutive expression of cytotoxic molecules (granzyme B, perforin) and innate-like receptors (such as NKG2D), enabling rapid, localised surveillance and immediate response to epithelial stress. GOC:tfm MP:0008894 + PMID:29674648 + WIKIPEDIA:Intraepithelial_lymphocyte @@ -81237,6 +81311,7 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest 2011-03-06T03:37:09Z BTO:0004910 FMA:75802 + RPE @@ -81263,6 +81338,13 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest DOI:10.3389/fphar.2021.727870/full https://www.sciencedirect.com/topics/chemistry/retinal-pigment + + + + RPE + PMID:35835183 + + @@ -81375,9 +81457,11 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest A vascular associated smooth muscle cell of the brain vasculature. + 2011-03-06T05:01:20Z + smooth muscle cell of the brain vasculature @@ -83798,6 +83882,12 @@ Their position at the interface between the internal environment and the externa + + + + + + A squamous shaped endothelial cell. 2011-07-08T03:31:25Z @@ -84052,6 +84142,7 @@ Their position at the interface between the internal environment and the externa + A luminal epithelial cell of the lactiferous duct. This cuboidal epithelial cell expresses keratin-18 and is estrogen-receptor alpha positive. 2011-07-11T01:44:48Z @@ -84183,26 +84274,30 @@ Their position at the interface between the internal environment and the externa - - An otic fibrocyte that underlies the spiral prominence and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. + + A spiral ligament fibrocyte that is located near the spiral prominence between the basilar crest and the stria and plays an important role in potassium recycling by actively pumping K+ from the extracellular space and facilitating transcellular K+ transport through gap junctions toward Type I fibrocytes. In mice, Type II fibrocytes express connexin 26 (Gjb2) and connexin 30 (Gjb6) as part of the mesenchymal gap junction system, as well as the Na‑K‑2Cl cotransporter NKCC1. 2011-07-11T03:40:40Z - type II otic fibrocyte - type II spiral ligament fibrocyte - type 2 otic fibrocyte + type 2 otic fibrocyte + type 2 spiral ligament fibrocyte + type II SLF + type II spiral ligament fibrocyte - An otic fibrocyte that underlies the spiral prominence and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. + A spiral ligament fibrocyte that is located near the spiral prominence between the basilar crest and the stria and plays an important role in potassium recycling by actively pumping K+ from the extracellular space and facilitating transcellular K+ transport through gap junctions toward Type I fibrocytes. In mice, Type II fibrocytes express connexin 26 (Gjb2) and connexin 30 (Gjb6) as part of the mesenchymal gap junction system, as well as the Na‑K‑2Cl cotransporter NKCC1. GOC:tfm PMID:18353863 + PMID:19080786 + PMID:33193034 - - type II spiral ligament fibrocyte - MP:0004488 + + type II SLF + PMID:33193034 + @@ -84210,20 +84305,30 @@ Their position at the interface between the internal environment and the externa - - An otic fibrocyte that resides above the stria vasularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. + + A spiral ligament fibrocyte located in the suprastrial region above the stria vascularis, distinguished from other fibrocytes by their unique expression of COX-1 in guinea pigs and end-foot structures that directly contact capillaries (Dai and Shi, 2011). This fibro-vascular coupling enables type V fibrocytes to regulate cochlear blood flow by translating Ca²⁺ signals into capillary vasodilation via COX-1-derived prostaglandins. This cell also participates in K⁺ recycling, expressing Na,K-ATPase (ATP1A1, ATP1B1) in mice and humans, and connexin 26/30 gap junctions enabling intercellular K⁺ transport within the spiral ligament syncytium (Peeleman et al., 2020). 2011-07-11T03:40:42Z + type 5 otic fibrocyte type V otic fibrocyte - type V spiral ligament fibrocyte - type 5 otic fibrocyte + type V SLF + type V spiral ligament fibrocyte - An otic fibrocyte that resides above the stria vasularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. + A spiral ligament fibrocyte located in the suprastrial region above the stria vascularis, distinguished from other fibrocytes by their unique expression of COX-1 in guinea pigs and end-foot structures that directly contact capillaries (Dai and Shi, 2011). This fibro-vascular coupling enables type V fibrocytes to regulate cochlear blood flow by translating Ca²⁺ signals into capillary vasodilation via COX-1-derived prostaglandins. This cell also participates in K⁺ recycling, expressing Na,K-ATPase (ATP1A1, ATP1B1) in mice and humans, and connexin 26/30 gap junctions enabling intercellular K⁺ transport within the spiral ligament syncytium (Peeleman et al., 2020). GOC:tfm PMID:18353863 + PMID:21673815 + PMID:33193034 + + + + + type V SLF + PMID:33193034 + @@ -84231,26 +84336,30 @@ Their position at the interface between the internal environment and the externa - - An otic fibrocyte that is lateral to the basilar membrane and anchoris it to the lateral wall. + + A spiral ligament fibrocyte that is located in the triangular space inferior to the crista basilaris (basilar crest). This cell is spindle-shaped and expresses NKCC1 but minimal to no Na,K-ATPase (ATP1A1, ATP1B1) in mice and humans, and lacks connexin 26/30 in mice, indicating it does not participate in K⁺ recycling, unlike type II fibrocytes. Type IV fibrocyte is uniquely characterised by strong expression of connective tissue growth factor (CTGF) in mice, suggesting roles in tissue remodelling and paracrine signalling to other cochlear cells. 2011-07-11T03:40:46Z - type IV otic fibrocyte - type IV spiral ligament fibrocyte - type 4 otic fibrocyte + type 4 otic fibrocyte + type 4 spiral ligament fibrocyte + type IV SLF + type IV spiral ligament fibrocyte - An otic fibrocyte that is lateral to the basilar membrane and anchoris it to the lateral wall. + A spiral ligament fibrocyte that is located in the triangular space inferior to the crista basilaris (basilar crest). This cell is spindle-shaped and expresses NKCC1 but minimal to no Na,K-ATPase (ATP1A1, ATP1B1) in mice and humans, and lacks connexin 26/30 in mice, indicating it does not participate in K⁺ recycling, unlike type II fibrocytes. Type IV fibrocyte is uniquely characterised by strong expression of connective tissue growth factor (CTGF) in mice, suggesting roles in tissue remodelling and paracrine signalling to other cochlear cells. GOC:tfm PMID:18353863 + PMID:19277783 + PMID:33193034 - - type IV spiral ligament fibrocyte - MP:0004490 + + type IV SLF + PMID:33193034 + @@ -84258,26 +84367,38 @@ Their position at the interface between the internal environment and the externa - - An otic fibrocyte that lines the otic capsule. + + A spiral ligament fibrocyte that is located in the deepest part of the inferior spiral ligament, directly lining the bony otic capsule. Distinguished from ion-transporting Type I and II fibrocytes, it utilises actin-myosin stress fibres and anchoring interactions to regulate basilar membrane tension. It has an elongated morphology, is most numerous in the basal, high-frequency cochlea, and expresses contractile and cytoskeletal proteins in mice, including α‑smooth muscle actin, non‑muscle myosin II, caldesmon, and the water channel Aquaporin‑1(Mahendrasingam et al., 2011; Kelly et al., 2012). 2011-07-11T03:40:50Z - type III otic fibrocyte - type III spiral ligament fibrocyte - type 3 otic fibrocyte + type 3 otic fibrocyte + tension fibroblast + type 3 spiral ligament fibrocyte + type III SLF + type III spiral ligament fibrocyte - An otic fibrocyte that lines the otic capsule. + A spiral ligament fibrocyte that is located in the deepest part of the inferior spiral ligament, directly lining the bony otic capsule. Distinguished from ion-transporting Type I and II fibrocytes, it utilises actin-myosin stress fibres and anchoring interactions to regulate basilar membrane tension. It has an elongated morphology, is most numerous in the basal, high-frequency cochlea, and expresses contractile and cytoskeletal proteins in mice, including α‑smooth muscle actin, non‑muscle myosin II, caldesmon, and the water channel Aquaporin‑1(Mahendrasingam et al., 2011; Kelly et al., 2012). GOC:tfm PMID:18353863 + PMID:22043022 + PMID:22476723 + PMID:33193034 - type III spiral ligament fibrocyte - MP:0004489 + tension fibroblast + PMID:33193034 + + + + + type III SLF + PMID:33193034 + @@ -84285,26 +84406,36 @@ Their position at the interface between the internal environment and the externa - - An otic fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. + + + + + + + + A spiral ligament fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. In mice, expression of connexin 26 (Gjb2) and connexin 30 (Gjb6) serves as a distinguishing molecular signature. 2011-07-11T03:39:27Z - type I otic fibrocyte - type I spiral ligament fibrocyte - type 1 otic fibrocyte + type 1 otic fibrocyte + type 1 spiral ligament fibrocyte + type I SLF + type I spiral ligament fibrocyte - An otic fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. + A spiral ligament fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. In mice, expression of connexin 26 (Gjb2) and connexin 30 (Gjb6) serves as a distinguishing molecular signature. GOC:tfm PMID:18353863 + PMID:18581144 + PMID:33193034 - - type I spiral ligament fibrocyte - MP:0004487 + + type I SLF + PMID:33193034 + @@ -84359,6 +84490,7 @@ In contrast to endothelial tip cells, which migrate and lead the angiogenic spro + @@ -86576,20 +86708,27 @@ The intrinsic tongue muscle cells, on the other hand, originate and function wit - A monostratified retinal ganglion cell with large soma and large dendritic field. + A large-bodied retinal projection neuron with wide monostratified dendritic arbors in defined IPL strata, high neurofilament and osteopontin expression, and a thick, fast-conducting axon. It shows short-latency, non-direction-selective responses with large receptive fields and a distinctive rapid action potential waveform. In mammals it forms about five percent of RGCs and includes four conserved ON and OFF sustained and transient subtypes. https://orcid.org/0000-0001-7258-9596 https://orcid.org/0000-0002-5260-9315 BAMS:1009 alpha cell + retinal ganglion cell A cell CL:0004117 This group includes all of the large bodied/large field RGCs in the rat. Group RGA cells have large somata (15 to 39 micrometers in diameter) and large, radially branching dendritic fields (235 to 748 micrometers in diameter), and many exhibit tracer coupling. - retinal ganglion cell A + alpha retinal ganglion cell (Mmus) - A monostratified retinal ganglion cell with large soma and large dendritic field. + A large-bodied retinal projection neuron with wide monostratified dendritic arbors in defined IPL strata, high neurofilament and osteopontin expression, and a thick, fast-conducting axon. It shows short-latency, non-direction-selective responses with large receptive fields and a distinctive rapid action potential waveform. In mammals it forms about five percent of RGCs and includes four conserved ON and OFF sustained and transient subtypes. + PMID:28753612 + + + + + retinal ganglion cell A PMID:12209831 @@ -88217,6 +88356,7 @@ The intrinsic tongue muscle cells, on the other hand, originate and function wit + @@ -88247,6 +88387,7 @@ The intrinsic tongue muscle cells, on the other hand, originate and function wit + @@ -88276,6 +88417,7 @@ The intrinsic tongue muscle cells, on the other hand, originate and function wit + @@ -88305,6 +88447,7 @@ The intrinsic tongue muscle cells, on the other hand, originate and function wit + @@ -88334,6 +88477,7 @@ The intrinsic tongue muscle cells, on the other hand, originate and function wit + @@ -89302,6 +89446,7 @@ Although hepatoblasts are specified embryonic liver cells that are bipotential f + @@ -89367,6 +89512,7 @@ Although hepatoblasts are specified embryonic liver cells that are bipotential f + @@ -89391,6 +89537,7 @@ Although hepatoblasts are specified embryonic liver cells that are bipotential f + @@ -89422,6 +89569,7 @@ Although hepatoblasts are specified embryonic liver cells that are bipotential f + @@ -90483,18 +90631,18 @@ Covers cells actively being cultured or stored in a quiescent state for future u - + A skeletal muscle satellite cell that has become mitotically active - typically following muscle damage. activated skeletal muscle satellite cell - + - + More accurately - transformation_of ? @@ -92155,7 +92303,7 @@ The role of Paneth cells specifically in the colon is of interest in the context - + @@ -92340,6 +92488,7 @@ TA: Transit Amplifying Cells + @@ -96226,6 +96375,7 @@ Functionally, the endothelial cells of the uterus are paramount in regulating th + @@ -96574,20 +96724,20 @@ Furthermore, cardiac endothelial cells control the passage of nutrients, hormone - + Any photoreceptor cell that is part of some camera-type eye. camera type eye photoreceptor cell camera-type eye photoreceptor cell camera-type eye photoreceptor cell - + - + https://github.com/obophenotype/cell-ontology/issues/2245 @@ -97216,13 +97366,7 @@ GABAergic interneurons are not a homogenous group, they vary in terms of morphol - - - - - - - + A cerebellar interneuron characterized by a spindle-shaped or triangular soma, parasagittally oriented and located at the border between the granular layer and the Purkinje cell layer. The Lugaro cell extends dendrites predominantly in the parasagittal plane, forming synaptic interactions with basket, stellate, and Golgi cells. Its axonal projections extend upward into the molecular layer, where they form a parasagittal plexus and emit long transverse collaterals that run parallel to the long axis of the cerebellar folia. The Lugaro cell is capable of co-releasing GABA and glycine, as evidenced by the expression of glutamate decarboxylase (GAD65/67) and the glycine transporter GlyT2. globular cell Lugaro cell @@ -97598,6 +97742,7 @@ Disorders or aberrations in the development or migration of the neural crest cel + @@ -97789,7 +97934,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -100312,9 +100456,11 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi) of primates, in the central “core” region. It expresses parvalbumin, is primarily GABAergic, and projects to motor thalamic nuclei including the ventral anterior, ventrolateral, and ventromedial nuclei. In the rodent homolog (entopeduncular nucleus), the core subregion is characterized by concentrated parvalbumin-positive neurons targeting the ventral anterior-ventral lateral thalamic nucleus and receives inputs from the dorsolateral striatum innervated by sensorimotor cortices (Miyamoto & Fukuda, 2022). This neuron corresponds to the sensorimotor output population of the GPi, as demonstrated in human tissue and cross-species comparative studies (Wallace et al., 2017) and by classic tracing in primates (Parent & De Bellefeuille, 1982; Parent et al., 2001). + 2025-01-31T00:00:00Z GPi core + internal globus pallidus core projecting neuron @@ -100364,9 +100510,11 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi), in the peripheral 'shell' region. In mice and primates, it expresses somatostatin and shows dual expression of GABAergic and glutamatergic markers, enabling co-release of GABA and glutamate (Wallace et al., 2017). It projects primarily to the lateral habenula (Parent & De Bellefeuille, 1982; Wallace et al., 2017), forming the limbic/aversive output stream of the GPi. + 2025-09-30T14:21:41Z GPi shell + internal globus pallidus shell projection neuron @@ -100393,6 +100541,17 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith + + + + + + + + + + + @@ -100430,7 +100589,9 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith A transcriptomically defined GABAergic neuron coexpressing dopamine located in the olfactory bulb and part of the striatum. + https://orcid.org/0000-0002-5507-2103 + OB-Dopa-GABA @@ -100450,8 +100611,10 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith STRd Cholinergic GABA A transcriptomically defined GABAergic neuron in the dorsal striatum. In mice and primates, it is defined by the coexpression of choline acetyltransferase (ChAT) together with the GABAergic markers glutamate decarboxylase 65 (GAD65/Gad2) and vesicular GABA transporter (VGAT/Slc32a1) (Lozovaya et al., 2018). + 2025-10-23T08:36:33Z + dorso-striatal cholinergic-GABAergic neuron @@ -100474,9 +100637,11 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith STR Cholinergic GABA A large aspiny interneuron of the striatum that serves as the principal intrinsic source of acetylcholine while simultaneously releasing GABA. It is defined by coexpression of cholinergic markers (ChAT and VAChT/Slc18a3) and GABAergic markers (GAD65/Gad2 and VGAT/Slc32a1) (Lozovaya et al., 2018). This MGE-derived neuron maintains Lhx6 expression associated with dual-transmitter identity (Fragkouli et al., 2009; Marin et al., 2000). Morphologically, it possesses a large soma (20–50 μm diameter), 2–4 thick aspiny dendrites extending radially ~1 mm, and locally ramified axons with hundreds of thousands of varicosities (Wilson et al., 1990; Lim et al., 2014). + Although they constitute only 1–3% of all striatal neurons, these interneurons form a major modulatory hub, integrating cortical, thalamic, and dopaminergic inputs and shaping striatal output dynamics (Gonzales & Smith, 2015; Wegman et al., 2024). Electrophysiologically, the neuron exhibits tonic autonomous firing at 3–10 Hz, broad action potentials, and a prominent hyperpolarization-activated inward current (Ih) (Bennett & Wilson, 1999; Goldberg & Reynolds, 2011). Functionally, it modulates corticostriatal and thalamostriatal synaptic transmission, dopamine release, and spiny projection neuron excitability through co-transmission of acetylcholine and GABA (Lozovaya et al., 2018; Wegman et al., 2024). This dual inhibitory and modulatory signaling underlies context-dependent control of synaptic plasticity, action selection, and reinforcement learning (Gonzales & Smith, 2015; Lozovaya et al., 2018). CGIN + striatal cholinergic-GABAergic neuron @@ -100537,9 +100702,11 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith GPe SOX6-CTXND1 GABA A GABAergic neuron located in the external globus pallidus (GPe) that constitutes approximately two-thirds of all GPe neurons (Mallet et al., 2012, Dodson et al., 2015). Derived from the medial ganglionic eminence, this cell selectively expresses Nkx2-1, with roughly two-thirds co-expressing parvalbumin (PV) and one-third lacking it in mice (Mallet et al., 2012; Dodson et al., 2015). + The prototypic neuron projects to downstream basal ganglia nuclei, including the subthalamic nucleus (STN), internal globus pallidus, and substantia nigra pars reticulata (SNr), with some neurons also emitting ascending collaterals that modestly innervate the striatum (Mallet et al., 2012, Abdi et al., 2015). It exhibits longer local axon collaterals with more boutons compared to arkypallidal neurons, supporting extensive local interconnectivity within the GPe (Mallet et al., 2012). The prototypic neuron plays a fundamental role in the indirect pathway of the basal ganglia, coordinating activity across basal ganglia nuclei through its widespread projections (Mallet et al., 2012, Courtney et al., 2023). Decreases in firing during movement are consistent with disinhibiting the STN and output nuclei, thereby facilitating the expression of desired motor patterns (Dodson et al., 2015, Courtney et al., 2023). 2025-10-17T09:12:54Z + prototypic neuron @@ -100579,8 +100746,10 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith GPe MEIS2-SOX6 GABA A GABAergic projection neuron located in the external segment of the globus pallidus (GPe) and defined by its exclusive projection to the dorsal striatum rather than to the subthalamic nucleus or basal ganglia output nuclei. In rodents and primates, it is characterized molecularly by expression of FOXP2, MEIS2, and NPAS1, and lacks expression of canonical pallidal markers NKX2-1 and LHX6 (Dodson et al., 2015; Abdi et al., 2015; Courtney et al., 2023). This neuron is GABAergic (GAD1/2⁺, SLC32A1/VGAT⁺) and typically PV⁻, forming the transcriptionally and developmentally LGE-derived subclass of GPe neurons (Dodson et al., 2015; Mallet et al., 2012). + 2025-10-16T10:21:41Z + arkypallidal neuron @@ -100798,6 +100967,7 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith + @@ -101286,6 +101456,1176 @@ Moreover, intestinal tuft cells are also involved in regulating intestinal epith + + + + + + + + + + + + + + + + + + A skeletal cell at the periosteal surface of the murine rib that displays hybrid osteochondral properties, emerging within the large callus that bridges segmental rib defects. It derives from a Sox9-expressing periosteal skeletal stem/progenitor subpopulation that constitutes only a small fraction of uninjured rib periosteum. After injury, these cells populate the callus and co-express cartilage and bone regulators Sox9 and Runx2, as well as matrix genes Col2a1 and Col1a1, while exhibiting dual chondrocyte/osteoblast properties. + + + GitHub Copilot + 2025-12-16T14:37:04Z + hybrid osteochondral skeletal cell + + + + + A skeletal cell at the periosteal surface of the murine rib that displays hybrid osteochondral properties, emerging within the large callus that bridges segmental rib defects. It derives from a Sox9-expressing periosteal skeletal stem/progenitor subpopulation that constitutes only a small fraction of uninjured rib periosteum. After injury, these cells populate the callus and co-express cartilage and bone regulators Sox9 and Runx2, as well as matrix genes Col2a1 and Col1a1, while exhibiting dual chondrocyte/osteoblast properties. + PMID:30983567 + + + + + + + + + + + + + + + + + + + + + + + + + + An epithelial cell that has a cuboidal morphology. + + GitHub Copilot + 2025-12-16T15:56:39Z + cuboidal epithelial cell + + + + + + + + + + + + + + + + + + + + + + + + + + + A CD4-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumors, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including the transcription factor TOX, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and T-bet, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and tissue environment. + + + + GitHub Copilot + 2026-01-13T15:30:05Z + CD4+ exhausted T lymphocyte + exhausted CD4 T cell + exhausted CD4-positive T cell + CD4-positive exhausted alpha-beta T cell + + + + + + true + + + + + A CD4-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumors, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including the transcription factor TOX, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and T-bet, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and tissue environment. + PMID:31207603 + PMID:31390978 + PMID:36907685 + PMID:38166256 + + + + + + + + + + + + + + + + + + + + + + + + + + + A CD8-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumours, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including expression of the transcription factor TOX and reduced T-bet, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and EOMES, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and disease context. + + + + GitHub Copilot + 2026-01-13T15:30:05Z + CD8+ exhausted T lymphocyte + exhausted CD8 T cell + exhausted CD8-positive T cell + CD8-positive exhausted alpha-beta T cell + + + + + + true + + + + + A CD8-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumours, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including expression of the transcription factor TOX and reduced T-bet, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and EOMES, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and disease context. + PMID:31207603 + PMID:36907685 + PMID:38166256 + + + + + + + + + A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (ON-transient α RGC, C41) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. + + CL:9900000 + oRGC2 + https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237215 + + + + + A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (ON-transient α RGC, C41) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. + PMID:31784286 + PMID:37066415 + + + + + https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237215 + reference transcriptomic data on GEO + + + + + + + + + A CD4-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. + + + GitHub Copilot + 2026-01-12T12:14:30Z + CD4+ T memory stem cell + CD4+ TSCM cell + CD4-positive TSCM cell + stem cell memory CD4+ T-cell + stem cell memory CD4+ T-lymphocyte + stem cell memory CD4+ alpha-beta T cell + stem cell memory CD4-positive, alpha-beta T lymphocyte + stem cell–like memory CD4+ T cell + stem cell–like memory CD4-positive, alpha-beta T cell + stem cell memory CD4-positive, alpha-beta T cell + + + + + A CD4-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. + PMID:19525962 + PMID:21926977 + PMID:28060797 + + + + + CD4+ T memory stem cell + PMID:21926977 + + + + + CD4+ TSCM cell + PMID:21926977 + + + + + CD4-positive TSCM cell + PMID:21926977 + + + + + + + + + A CD8-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. + + + GitHub Copilot + 2026-01-12T12:14:30Z + CD8+ T memory stem cell + CD8+ TSCM cell + CD8-positive TSCM cell + stem cell memory CD8+ T-cell + stem cell memory CD8+ T-lymphocyte + stem cell memory CD8+ alpha-beta T cell + stem cell memory CD8-positive, alpha-beta T lymphocyte + stem cell–like memory CD8+ T cell + stem cell–like memory CD8-positive, alpha-beta T cell + stem cell memory CD8-positive, alpha-beta T cell + + + + + A CD8-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. + PMID:19525962 + PMID:21926977 + PMID:28060797 + + + + + CD8+ T memory stem cell + PMID:21926977 + + + + + CD8+ TSCM cell + PMID:21926977 + + + + + CD8-positive TSCM cell + PMID:21926977 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. + https://github.com/obophenotype/cell-ontology/issues/3455 + + GitHub Copilot + 2026-01-05T11:44:26Z + intestinal intraepithelial lymphocyte + + + + + A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. + PMID:29674648 + WIKIPEDIA:Intraepithelial_lymphocyte + + + + + + + + + A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (OFF-sustained alpha-RGC, C42) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. + + 2025-12-08T11:40:49Z + CL:9900001 + oRGC1 + https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237215 + + + + + A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (OFF-sustained alpha-RGC, C42) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. + PMID:31784286 + PMID:37066415 + + + + + https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237215 + reference transcriptomic data on GEO + + + + + + + + + + + + + + + An articular chondrocyte located in the most superficial zone of articular cartilage, characterized by flattened morphology and tangential alignment parallel to the joint surface, and residing within a matrix of fine collagen fibrils and relatively low proteoglycan content. In mice and humans, this cell typically expresses lubricin (PRG4) and contributes to lubrication and resistance to shear and tensile forces at the cartilage surface. + + 2026-02-18T11:06:13Z + superficial zone articular chondrocyte + + + + + An articular chondrocyte located in the most superficial zone of articular cartilage, characterized by flattened morphology and tangential alignment parallel to the joint surface, and residing within a matrix of fine collagen fibrils and relatively low proteoglycan content. In mice and humans, this cell typically expresses lubricin (PRG4) and contributes to lubrication and resistance to shear and tensile forces at the cartilage surface. + PMID:23015907 + PMID:23124445 + PMID:41226342 + + + + + + + + + An articular chondrocyte located in the middle (transitional) zone of articular cartilage, characterized by round morphology and relatively random spatial organization, and residing in a matrix enriched in proteoglycans and thicker collagen fibrils oriented obliquely to the articular surface. This cell contributes to the largest volume fraction of articular cartilage and functions primarily in distributing and absorbing compressive loads between the superficial and deep zones. + + 2026-02-18T11:06:13Z + transitional zone articular chondrocyte + middle zone articular chondrocyte + + + + + An articular chondrocyte located in the middle (transitional) zone of articular cartilage, characterized by round morphology and relatively random spatial organization, and residing in a matrix enriched in proteoglycans and thicker collagen fibrils oriented obliquely to the articular surface. This cell contributes to the largest volume fraction of articular cartilage and functions primarily in distributing and absorbing compressive loads between the superficial and deep zones. + PMID:23015907 + PMID:23124445 + PMID:41226342 + + + + + transitional zone articular chondrocyte + PMID:23015907 + + + + + + + + + + + + + + + An articular chondrocyte located in the deep (radial) zone of articular cartilage, characterized by columnar arrangement perpendicular to the joint surface and residence within a matrix containing the highest proteoglycan concentration and large-diameter collagen fibrils oriented radially. In humans, this cell expresses collagen type X (COL10A1) and provides maximal resistance to compressive forces. It is positioned adjacent to the tidemark, where collagen fibrils extend into the calcified cartilage to anchor the articular cartilage to subchondral bone. + + 2026-02-18T11:06:13Z + radial zone articular chondrocyte + deep zone articular chondrocyte + + + + + An articular chondrocyte located in the deep (radial) zone of articular cartilage, characterized by columnar arrangement perpendicular to the joint surface and residence within a matrix containing the highest proteoglycan concentration and large-diameter collagen fibrils oriented radially. In humans, this cell expresses collagen type X (COL10A1) and provides maximal resistance to compressive forces. It is positioned adjacent to the tidemark, where collagen fibrils extend into the calcified cartilage to anchor the articular cartilage to subchondral bone. + PMID:23015907 + PMID:23124445 + PMID:41226342 + + + + + radial zone articular chondrocyte + PMID:23015907 + + + + + + + + + + + + + + + An articular chondrocyte located in the calcified cartilage zone below the tidemark at the interface between articular cartilage and subchondral bone, embedded within a mineralized extracellular matrix. In humans, this cell exhibits a hypertrophic-like phenotype and typically expresses collagen type X (COL10A1). Together with the surrounding calcified matrix, it forms a transitional region that mechanically couples the deep articular cartilage to the underlying subchondral bone. + + 2026-02-18T11:06:13Z + calcified zone articular chondrocyte + + + + + An articular chondrocyte located in the calcified cartilage zone below the tidemark at the interface between articular cartilage and subchondral bone, embedded within a mineralized extracellular matrix. In humans, this cell exhibits a hypertrophic-like phenotype and typically expresses collagen type X (COL10A1). Together with the surrounding calcified matrix, it forms a transitional region that mechanically couples the deep articular cartilage to the underlying subchondral bone. + PMID:18455690 + PMID:23015907 + PMID:41226342 + + + + + + + + + A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (ON-sustained α RGC, C43) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. + + CL:9900001 + oRGC4 + https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237215 + + + + + A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (ON-sustained α RGC, C43) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. + PMID:31784286 + PMID:37066415 + + + + + https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237215 + reference transcriptomic data on GEO + + + + + + + + + A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (OFF-transient α RGC, C45) (Hahn et al., 2023; Tran et al., 2019). Reference to transcriptomic evidence can be found at: GSE237215. + + 2025-12-08T11:46:13Z + oRGC5 + https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237215 + + + + + A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (OFF-transient α RGC, C45) (Hahn et al., 2023; Tran et al., 2019). Reference to transcriptomic evidence can be found at: GSE237215. + PMID:31784286 + PMID:37066415 + + + + + https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237215 + reference transcriptomic data on GEO + + + + + + + + + + + + + + + + + + + + + + + + + + A mesenchymal stromal cell of the deep fascia (e.g., fascia lata) that is vimentin-positive, CD68-negative, and S-100A4-positive, organized in small clusters at the interface between fibrous fascial sublayers and loose connective tissue. It is specialized for hyaluronan-rich ECM biosynthesis, as evidenced by HAS2 mRNA expression, Alcian Blue staining, and anti-HABP immunoreactivity, and functions to regulate fascial gliding and viscoelasticity. + + + 2026-02-20T14:27:58Z + Stecco et al. demonstrate that fasciacytes differ from classical fascial fibroblasts in morphology, location (small clusters at the interface between fibrous and loose fascial layers), marker profile (S-100A4 expression), and ECM output (HA-rich rather than collagen-rich). + fasciacyte + + + + + A mesenchymal stromal cell of the deep fascia (e.g., fascia lata) that is vimentin-positive, CD68-negative, and S-100A4-positive, organized in small clusters at the interface between fibrous fascial sublayers and loose connective tissue. It is specialized for hyaluronan-rich ECM biosynthesis, as evidenced by HAS2 mRNA expression, Alcian Blue staining, and anti-HABP immunoreactivity, and functions to regulate fascial gliding and viscoelasticity. + PMID:29575206 + PMID:33573365 + + + + + + + + + + + + + + + + + + + + + Muscle precursor cells that delaminate from the dermomyotome after epithelial-to-mesenchymal transition (EMT) and undergo long-range migration while retaining proliferative capacity. + + MMP + migratory muscle precursor + + + + + Muscle precursor cells that delaminate from the dermomyotome after epithelial-to-mesenchymal transition (EMT) and undergo long-range migration while retaining proliferative capacity. + PMID:11081511 + PMID:16977478 + PMID:21720828 + + + + + MMP + PMID:21720828 + + + + + + + + + + A neuron characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes (multiaxonal) that extend without branching until they reach their targets. The soma lacks the short lamellar or spiny dendrites characteristic of Dogiel type I neurons. Dogiel type II neurons were first described by Alexander Dogiel in 1899 based on methylene blue staining in gastrointestinal ganglia. In the enteric nervous system, Dogiel type II neurons correspond to intrinsic primary afferent neurons (IPANs) and exhibit AH-type electrophysiology (prolonged afterhyperpolarization following an action potential). + + GitHub Copilot + 2026-03-10T14:42:58Z + multiaxonal enteric neuron + type II enteric neuron + AH neuron + Dogiel II neuron + Dogiel type II neuron + + + + + A neuron characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes (multiaxonal) that extend without branching until they reach their targets. The soma lacks the short lamellar or spiny dendrites characteristic of Dogiel type I neurons. Dogiel type II neurons were first described by Alexander Dogiel in 1899 based on methylene blue staining in gastrointestinal ganglia. In the enteric nervous system, Dogiel type II neurons correspond to intrinsic primary afferent neurons (IPANs) and exhibit AH-type electrophysiology (prolonged afterhyperpolarization following an action potential). + PMID:34170401 + + + + + multiaxonal enteric neuron + PMID:34170401 + + + + + type II enteric neuron + PMID:34170401 + + + + + AH neuron + PMID:34170401 + + + + + + Dogiel II neuron + PMID:34170401 + + + + + + + + + + + + + + + + + A sensory neuron of the enteric nervous system whose soma resides in the myenteric plexus and which functions as the afferent limb of intrinsic reflex circuits controlling motility, secretion, and blood flow. This neuron is characterised by Dogiel type II morphology (large smooth soma with multiple long axon-like processes), AH-type electrophysiology (prolonged afterhyperpolarization following an action potential), and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). + + GitHub Copilot + 2026-03-10T14:42:58Z + multiaxonal cholinergic myenteric sensory neuron + myenteric sensory neuron + IPAN + intrinsic primary afferent neuron of myenteric plexus + + + + + A sensory neuron of the enteric nervous system whose soma resides in the myenteric plexus and which functions as the afferent limb of intrinsic reflex circuits controlling motility, secretion, and blood flow. This neuron is characterised by Dogiel type II morphology (large smooth soma with multiple long axon-like processes), AH-type electrophysiology (prolonged afterhyperpolarization following an action potential), and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). + PMID:34170401 + PMID:37355216 + PMID:40954253 + + + + + multiaxonal cholinergic myenteric sensory neuron + PMID:37355216 + + + + + myenteric sensory neuron + PMID:34170401 + + + + + IPAN + PMID:34170401 + + + + + + + + + + + + + + + + An interneuron of the enteric nervous system whose soma resides in the myenteric plexus. Interneurons of the myenteric plexus integrate sensory input from intrinsic primary afferent neurons (IPANs) and modulate motor output to smooth muscle and secretory epithelia by synapsing onto motor neurons and other interneurons within the plexus. + + GitHub Copilot + 2026-03-10T14:42:58Z + enteric interneuron of myenteric plexus + interneuron of myenteric plexus + + + + + An interneuron of the enteric nervous system whose soma resides in the myenteric plexus. Interneurons of the myenteric plexus integrate sensory input from intrinsic primary afferent neurons (IPANs) and modulate motor output to smooth muscle and secretory epithelia by synapsing onto motor neurons and other interneurons within the plexus. + PMID:32888429 + PMID:34170401 + PMID:40954253 + + + + + enteric interneuron of myenteric plexus + PMID:34170401 + + + + + + + + + + + + + + + An enteric neuron whose soma resides in the myenteric plexus and which controls mucosal secretion and blood flow by innervating secretory epithelia and submucosal blood vessels. This neuron is characterised by expression of vasoactive intestinal peptide (VIP). In mouse, two Glp2r+ subtypes have been identified: PSVN1 (VIP+, non-cholinergic) and PSVN2 (ChAT+, cholinergic). In human, only the VIP+ non-cholinergic subtype has been detected. + + GitHub Copilot + 2026-03-10T14:42:58Z + VIP-positive secretomotor neuron + PSVN + secretomotor/vasodilator neuron of myenteric plexus + + + + + An enteric neuron whose soma resides in the myenteric plexus and which controls mucosal secretion and blood flow by innervating secretory epithelia and submucosal blood vessels. This neuron is characterised by expression of vasoactive intestinal peptide (VIP). In mouse, two Glp2r+ subtypes have been identified: PSVN1 (VIP+, non-cholinergic) and PSVN2 (ChAT+, cholinergic). In human, only the VIP+ non-cholinergic subtype has been detected. + PMID:32888429 + PMID:34170401 + PMID:40954253 + + + + + VIP-positive secretomotor neuron + PMID:32888429 + + + + + PSVN + PMID:34170401 + + + + + + + + + + + + + + + + An enteric neuron whose soma resides in the myenteric plexus of the intestine and whose axon projects outside the gut wall to synapse on neurons in prevertebral sympathetic ganglia (celiac, superior mesenteric, or inferior mesenteric ganglia). This neuron provides a pathway for gut-to-brain communication via sympathetic prevertebral ganglia. In humans, 89% are immunopositive for choline acetyltransferase (ChAT); CART (cocaine- and amphetamine-regulated transcript) is NOT a human marker (0% CART+) but is present in rodent viscerofugal neurons. + + GitHub Copilot + 2026-03-10T14:42:58Z + cholinergic viscerofugal neuron + viscerofugal neuron + VFN + intestinofugal neuron + + + + + An enteric neuron whose soma resides in the myenteric plexus of the intestine and whose axon projects outside the gut wall to synapse on neurons in prevertebral sympathetic ganglia (celiac, superior mesenteric, or inferior mesenteric ganglia). This neuron provides a pathway for gut-to-brain communication via sympathetic prevertebral ganglia. In humans, 89% are immunopositive for choline acetyltransferase (ChAT); CART (cocaine- and amphetamine-regulated transcript) is NOT a human marker (0% CART+) but is present in rodent viscerofugal neurons. + PMID:34170401 + PMID:38292899 + PMID:40954253 + + + + + cholinergic viscerofugal neuron + PMID:38292899 + + + + + viscerofugal neuron + PMID:38292899 + + + + + VFN + PMID:38292899 + + + + + + + + + + An interneuron of the myenteric plexus whose axon projects orally (in the ascending direction) along the gut axis. This neuron is immunopositive for choline acetyltransferase (ChAT) and enkephalin (ENK), and forms the excitatory limb of ascending reflex pathways that coordinate peristalsis. + + GitHub Copilot + 2026-03-10T14:42:58Z + ascending myenteric interneuron + cholinergic enkephalinergic myenteric interneuron + ascending interneuron of myenteric plexus + + + + + An interneuron of the myenteric plexus whose axon projects orally (in the ascending direction) along the gut axis. This neuron is immunopositive for choline acetyltransferase (ChAT) and enkephalin (ENK), and forms the excitatory limb of ascending reflex pathways that coordinate peristalsis. + PMID:34170401 + PMID:40954253 + + + + + ascending myenteric interneuron + PMID:34170401 + + + + + cholinergic enkephalinergic myenteric interneuron + PMID:34170401 + + + + + + + + + An interneuron of the myenteric plexus whose axon projects aborally (in the descending direction) along the gut axis. This neuron class encompasses multiple chemically diverse subtypes including serotonergic (5-HT+), nitrergic (NOS1+), and other populations, forming the inhibitory limb of descending reflex pathways. + + GitHub Copilot + 2026-03-10T14:42:58Z + descending myenteric interneuron + descending interneuron of myenteric plexus + + + + + An interneuron of the myenteric plexus whose axon projects aborally (in the descending direction) along the gut axis. This neuron class encompasses multiple chemically diverse subtypes including serotonergic (5-HT+), nitrergic (NOS1+), and other populations, forming the inhibitory limb of descending reflex pathways. + PMID:34170401 + PMID:40954253 + + + + + descending myenteric interneuron + PMID:34170401 + + + + + + + + + + A Dogiel type I neuron of the myenteric plexus characterised by stubby (lamellar) dendrite morphology with broad, flattened dendritic expansions. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1), corresponding to excitatory motor neurons of the enteric nervous system. + + GitHub Copilot + 2026-03-10T14:42:58Z + lamellar Dogiel type I neuron + stubby Dogiel I neuron + stubby Dogiel type I neuron of myenteric plexus + + + + + A Dogiel type I neuron of the myenteric plexus characterised by stubby (lamellar) dendrite morphology with broad, flattened dendritic expansions. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1), corresponding to excitatory motor neurons of the enteric nervous system. + PMID:34170401 + PMID:37355216 + + + + + lamellar Dogiel type I neuron + PMID:34170401 + + + + + stubby Dogiel I neuron + PMID:34170401 + + + + + + + + + A Dogiel type I neuron of the myenteric plexus characterised by spiny (spine-like) dendrite morphology with numerous short projections along the dendrites. This neuron is immunopositive for neuronal nitric oxide synthase (NOS1) and immunonegative for choline acetyltransferase (ChAT), corresponding to inhibitory motor neurons of the enteric nervous system. + + GitHub Copilot + 2026-03-10T14:42:58Z + spiny Dogiel I neuron + spiny Dogiel type I neuron of myenteric plexus + + + + + A Dogiel type I neuron of the myenteric plexus characterised by spiny (spine-like) dendrite morphology with numerous short projections along the dendrites. This neuron is immunopositive for neuronal nitric oxide synthase (NOS1) and immunonegative for choline acetyltransferase (ChAT), corresponding to inhibitory motor neurons of the enteric nervous system. + PMID:34170401 + PMID:37355216 + + + + + spiny Dogiel I neuron + PMID:34170401 + + + + + + + + + + An intrinsic primary afferent neuron of the myenteric plexus characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes that extend without branching until they reach their targets in both the myenteric and submucosal plexuses and the mucosa. The soma lacks the dendrites characteristic of Dogiel type I neurons and is larger in cross-sectional area than either motor neuron type. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). It exhibits AH-type electrophysiology, characterised by a prolonged afterhyperpolarization (AHP) following an action potential. Substance P (encoded by TAC1) expression has been reported in subsets across species. + + GitHub Copilot + 2026-03-10T14:42:58Z + AH-type myenteric neuron + multiaxonal myenteric sensory neuron + type II myenteric neuron + Dogiel type II neuron of myenteric plexus + + + + + An intrinsic primary afferent neuron of the myenteric plexus characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes that extend without branching until they reach their targets in both the myenteric and submucosal plexuses and the mucosa. The soma lacks the dendrites characteristic of Dogiel type I neurons and is larger in cross-sectional area than either motor neuron type. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). It exhibits AH-type electrophysiology, characterised by a prolonged afterhyperpolarization (AHP) following an action potential. Substance P (encoded by TAC1) expression has been reported in subsets across species. + PMID:34170401 + PMID:37355216 + PMID:40954253 + + + + + AH-type myenteric neuron + PMID:34170401 + + + + + multiaxonal myenteric sensory neuron + PMID:34170401 + + + + + type II myenteric neuron + PMID:34170401 + + + + + + + + + An intrinsic primary afferent neuron of the myenteric plexus that is immunopositive for calretinin. This neuron shares the Dogiel type II morphology and AH-type electrophysiology of all myenteric IPANs, and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). + + GitHub Copilot + 2026-03-10T14:42:58Z + calretinin-positive myenteric sensory neuron + SN1 + calretinin-positive intrinsic primary afferent neuron of myenteric plexus + + + + + An intrinsic primary afferent neuron of the myenteric plexus that is immunopositive for calretinin. This neuron shares the Dogiel type II morphology and AH-type electrophysiology of all myenteric IPANs, and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). + PMID:34170401 + PMID:37355216 + PMID:40954253 + + + + + calretinin-positive myenteric sensory neuron + PMID:37355216 + + + + + SN1 + PMID:37355216 + + + + + + + + + + An intrinsic primary afferent neuron of the myenteric plexus that lacks calretinin expression. This neuron shares the Dogiel type II morphology and AH-type electrophysiology of all myenteric IPANs, and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). + + GitHub Copilot + 2026-03-10T14:42:58Z + calretinin-negative myenteric sensory neuron + SN2 + calretinin-negative intrinsic primary afferent neuron of myenteric plexus + + + + + An intrinsic primary afferent neuron of the myenteric plexus that lacks calretinin expression. This neuron shares the Dogiel type II morphology and AH-type electrophysiology of all myenteric IPANs, and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). + PMID:34170401 + PMID:37355216 + PMID:40954253 + + + + + calretinin-negative myenteric sensory neuron + PMID:37355216 + + + + + SN2 + PMID:37355216 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An enteric neuron whose soma resides in the myenteric plexus and which is capable of acetylcholine secretion, neurotransmission. This is a defined grouping class that autoclassifies stubby Dogiel type I neurons, intrinsic primary afferent neurons, ascending interneurons, and their morphological/chemical subterms. + + GitHub Copilot + 2026-03-10T14:42:58Z + ChAT-positive myenteric neuron + cholinergic neuron of myenteric plexus + + + + + An enteric neuron whose soma resides in the myenteric plexus and which is capable of acetylcholine secretion, neurotransmission. This is a defined grouping class that autoclassifies stubby Dogiel type I neurons, intrinsic primary afferent neurons, ascending interneurons, and their morphological/chemical subterms. + PMID:34170401 + PMID:37355216 + + + + + ChAT-positive myenteric neuron + PMID:37355216 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An enteric neuron whose soma resides in the myenteric plexus and which is capable of nitric oxide biosynthetic process. This is a defined grouping class that autoclassifies spiny Dogiel type I neurons (the nitrergic motor neuron morphotype). + + GitHub Copilot + 2026-03-10T14:42:58Z + NOS1-positive myenteric neuron + nNOS-positive myenteric neuron + nitrergic neuron of myenteric plexus + + + + + An enteric neuron whose soma resides in the myenteric plexus and which is capable of nitric oxide biosynthetic process. This is a defined grouping class that autoclassifies spiny Dogiel type I neurons (the nitrergic motor neuron morphotype). + PMID:34170401 + PMID:37355216 + + + + + NOS1-positive myenteric neuron + PMID:37355216 + + + + + nNOS-positive myenteric neuron + PMID:37355216 + + + + @@ -103875,8 +105215,10 @@ Bronchial goblet cells have an innate defense mechanism wherein they increase se A goblet cell that is part of the epithelium of intestinal villus. + FMA:263046 goblet cell of epithelium of intestinal villus + intestinal villus goblet cell @@ -107458,6 +108800,7 @@ Moreover, these cells play a pivotal role in inflammation and coagulation proces + @@ -109277,6 +110620,7 @@ Beyond pigmentation and UV protection, melanocytes play roles in immune and infl + A basal cell that is part of the urothelium. Compared to other urothelial cell types, a basal cell of the urothelium is positioned along the basement membrane, is the most undifferentiated and serves a progenitor role. FMA:84150 @@ -115582,7 +116926,7 @@ Intestinal enteroendocrine cells also serve as the body's frontline of defe - + @@ -117157,6 +118501,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. 2014-02-11T17:29:04Z + PBMC CL:2000001 peripheral blood mononuclear cell @@ -117167,6 +118512,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. GOC:TermGenie + + + + PBMC + PMID:27696124 + + @@ -120358,6 +121710,7 @@ OSE cells are also the primary origin of ovarian cancer, specifically, epithelia + @@ -121772,6 +123125,7 @@ Sncg GABAergic cortical interneurons have a highly diverse morphology and physio ILX:0770150 + The marker set RXRG, THSD7B can identify the Human cell type sncg GABAergic interneuron in the neocortex with a confidence of 0.628943702 (NS-Forest FBeta value). sncg GABAergic interneuron https://cellxgene.cziscience.com/cellguide/CL_4023015 @@ -122105,6 +123459,7 @@ Disruptions in the function of pvalb GABAergic cortical interneurons are linked ILX:0770154 + Historically this term was used to refer to all Pvalb expressing GABAergic interneurons, but transcriptomic classification separates out some Pvalb expressing GABAergic interneurons as sibling classes (e.g. Pvalb chandelier). We follow the transcriptomic classifications. The marker set PVALB, TAC1, MYO5B can identify the Human cell type pvalb GABAergic interneuron in the neocortex with a confidence of 0.691998764 (NS-Forest FBeta value). pvalb GABAergic interneuron @@ -122728,11 +124083,9 @@ Disruptions in the function of pvalb GABAergic cortical interneurons are linked A neuron that is derived from a precursor cell in the lateral ganglion eminence. - https://orcid.org/0000-0001-7258-9596 https://orcid.org/0000-0002-7073-9172 LGE-derived neuron - lateral ganglionic eminence derived neuron @@ -122784,6 +124137,7 @@ Disruptions in the function of pvalb GABAergic cortical interneurons are linked ChC + The marker set GPR149, CA8 can identify the Human cell type pvalb chandelier GABAergic interneuron in the neocortex with a confidence of 0.799748111 (NS-Forest FBeta value). pvalb chandelier GABAergic interneuron @@ -123035,6 +124389,7 @@ The L5 extratelencephalic projecting glutamatergic cortical neuron is pivotal in L5b neuron + The marker set CHST8, POU3F1 can identify the Human cell type L5 extratelencephalic projecting glutamatergic cortical neuron in the neocortex with a confidence of 0.815891473 (NS-Forest FBeta value). L5 extratelencephalic projecting glutamatergic cortical neuron https://cellxgene.cziscience.com/cellguide/CL_4023041 @@ -123154,6 +124509,7 @@ The L5 extratelencephalic projecting glutamatergic cortical neuron is pivotal in L6 CT + The marker set SEMA5B, ADAMTSL1, SULF1 can identify the Human cell type L6 corticothalamic-projecting glutamatergic cortical neuron in the neocortex with a confidence of 0.631898455 (NS-Forest FBeta value). L6 corticothalamic-projecting glutamatergic cortical neuron @@ -123557,11 +124913,13 @@ Functionally, the L6 intratelencephalic projecting neurons integrate and transmi A transcriptomically distinct type of mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Non-neuronal cells', Author Categories: 'CrossArea_subclass', clusters VLMC. + ILX:0770143 VLMC + vascular leptomeningeal cell @@ -123711,9 +125069,9 @@ Functionally, the L6 intratelencephalic projecting neurons integrate and transmi - - - + + + A type of mouse mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. VLMC (Mus musculus) @@ -123721,34 +125079,34 @@ Functionally, the L6 intratelencephalic projecting neurons integrate and transmi vascular leptomeningeal cell (Mmus) - + - + - + - + PMID:30096314 - + PMID:30096314 - + PMID:30096314 @@ -123992,8 +125350,20 @@ Under pathological conditions, mesothelial fibroblasts of the leptomeninx may un + + + + + + + + + + + + MGE interneuron - An interneuron that is derived from the medial ganglionic eminence. + An interneuron that is derived from the medial ganglionic eminence. In mice and humans, it expresses LHX6 and SOX6. MGE interneuron @@ -124004,8 +125374,9 @@ Under pathological conditions, mesothelial fibroblasts of the leptomeninx may un - An interneuron that is derived from the medial ganglionic eminence. + An interneuron that is derived from the medial ganglionic eminence. In mice and humans, it expresses LHX6 and SOX6. DOI:10.1101/2022.10.12.511898 + PMID:19709629 @@ -129335,9 +130706,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A GABAergic neuron that resides in the islands of calleja and shows the cytoarchitectural and molecular features characteristic of this granule-like cell population. In mice and primates, it expresses D1 and D3 dopamine receptors (Drd1; Drd3), GABAergic markers (GAD1/2) and form densely packed granule cell clusters in the olfactory tubercle within the ventral striatum. Moreover it receives dense dopaminergic input from the VTA, and functionally associated with self-grooming behaviors and depression-like behaviors. + https://orcid.org/0000-0002-5507-2103 2023-06-14T13:37:45Z D1-ICj + In Rhesus macaques, the Island of Calleja granule cell type has been noted to have enriched gene expression of CPNE4. Islands of Calleja granule cell @@ -129655,6 +131028,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel ILX:0770156 L2/3 IT + Hystorically, the L2/3 intratelencephalic projectic glutametergic neuron was known to have its soma in cortical layer 2/3. MERFISH data showed that this intratelencephalic-projecting glutametergic neuron can have its soma in layer 2/3, 4B, 4C. The position of the soma in layer 4b and 4C is less frequent for this neuronal type in comparison to cortical layer 2/3. The marker set ONECUT2, COL5A2 can identify the Human cell type L2/3 intratelencephalic projecting glutamatergic neuron in the neocortex with a confidence of 0.670149932 (NS-Forest FBeta value). L2/3 intratelencephalic projecting glutamatergic neuron @@ -129859,6 +131233,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 2023-10-10T14:11:25Z L4 IT + Historically, the L4 intratelencephalic projectic glutametergic neuron was known to have its soma in cortical layer 4. MERFISH data showed that this intratelencephalic-projecting glutametergic neuron can also have its soma in layer 3. The marker set RORB, ST8SIA4 can identify the Human cell type L4 intratelencephalic projecting glutamatergic neuron in the neocortex with a confidence of 0.720108696 (NS-Forest FBeta value). L4 intratelencephalic projecting glutamatergic neuron @@ -129922,6 +131297,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel ILX:0770157 L5 IT + The marker set ARSJ, RORB, KCNK2 can identify the Human cell type L5 intratelencephalic projecting glutamatergic neuron in the neocortex with a confidence of 0.764261336 (NS-Forest FBeta value). L5 intratelencephalic projecting glutamatergic neuron @@ -129985,6 +131361,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel ILX:0770158 L6 IT + The marker set LINC00507, THEMIS can identify the Human cell type L6 intratelencephalic projecting glutamatergic neuron in the neocortex with a confidence of 0.641695703 (NS-Forest FBeta value). L6 intratelencephalic projecting glutamatergic neuron @@ -130036,7 +131413,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion. https://orcid.org/0000-0002-1425-877X 2023-10-13T11:22:42Z @@ -130044,14 +131421,14 @@ In addition to their secretory function, fallopian tube secretory epithelial cel ureteric bud cell - + - + PMID:9374839 @@ -130105,6 +131482,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 2023-11-17T11:35:06Z L5/6 NP + The marker set NPSR1-AS1, TLL1 can identify the Human cell type L5/6 near-projecting glutamatergic neuron in the neocortex with a confidence of 0.899288218 (NS-Forest FBeta value). L5/6 near-projecting glutamatergic neuron @@ -131221,6 +132599,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set SORCS3, TAFA1 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033019 in the retina with a confidence of 0.709302326 (NS-Forest FBeta value). The marker set TAFA1, ENSG00000250971 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033019 in the retina with a confidence of 0.797269292 (NS-Forest FBeta value). ON-blue cone bipolar cell + @@ -131253,6 +132632,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set TAFA1, ENSG00000250971 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033019 in the retina with a confidence of 0.797269292 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -131606,6 +132991,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set LAMA3, EBF1 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033027 in the retina with a confidence of 0.917474411 (NS-Forest FBeta value). The marker set NXPH2, EBF1 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033027 in the retina with a confidence of 0.752547687 (NS-Forest FBeta value). diffuse bipolar 1 cell + @@ -131659,6 +133045,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set NXPH2, EBF1 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033027 in the retina with a confidence of 0.752547687 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -131688,6 +133080,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set ENSG00000243004, ENSG00000249803 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033028 in the retina with a confidence of 0.770513807 (NS-Forest FBeta value). The marker set TAFA4, DSCAM can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033028 in the retina with a confidence of 0.886091243 (NS-Forest FBeta value). diffuse bipolar 2 cell + @@ -131722,6 +133115,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set TAFA4, DSCAM can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033028 in the retina with a confidence of 0.886091243 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -131752,6 +133151,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set ENSG00000267109 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033029 in the retina with a confidence of 0.848827502 (NS-Forest FBeta value). The marker set ERBB4 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033029 in the retina with a confidence of 0.949243066 (NS-Forest FBeta value). diffuse bipolar 3a cell + @@ -131794,6 +133194,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set ERBB4 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033029 in the retina with a confidence of 0.949243066 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -131823,6 +133229,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set ABCA4, DPP10 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033030 in the retina with a confidence of 0.765019652 (NS-Forest FBeta value). The marker set MEIS2, ENSG00000242021 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033030 in the retina with a confidence of 0.821782012 (NS-Forest FBeta value). diffuse bipolar 3b cell + @@ -131858,6 +133265,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set MEIS2, ENSG00000242021 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033030 in the retina with a confidence of 0.821782012 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -131871,6 +133284,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel DB4 cell diffuse bipolar 4 cell + @@ -131887,6 +133301,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel PMID:32032773 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -131915,6 +133335,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set ENSG00000275443 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033032 in the retina with a confidence of 0.817444508 (NS-Forest FBeta value). The marker set ENSG00000275443 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033032 in the retina with a confidence of 0.877512571 (NS-Forest FBeta value). diffuse bipolar 6 cell + @@ -131942,6 +133363,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set ENSG00000275443 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033032 in the retina with a confidence of 0.877512571 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -131970,6 +133397,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set NKAIN3, TAFA4 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033033 in the retina with a confidence of 0.915774104 (NS-Forest FBeta value). The marker set SCG2, TAFA4 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033033 in the retina with a confidence of 0.891115106 (NS-Forest FBeta value). flat midget bipolar cell + @@ -131997,6 +133425,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set SCG2, TAFA4 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033033 in the retina with a confidence of 0.891115106 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -132025,6 +133459,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set PTPRT, CARMIL1 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033034 in the retina with a confidence of 0.80078521 (NS-Forest FBeta value). The marker set RELN, ENSG00000271860 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033034 in the retina with a confidence of 0.884807812 (NS-Forest FBeta value). invaginating midget bipolar cell + @@ -132052,6 +133487,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set RELN, ENSG00000271860 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033034 in the retina with a confidence of 0.884807812 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -132081,6 +133522,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set UTRN can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033035 in the retina with a confidence of 0.808459341 (NS-Forest FBeta value). The marker set UTRN, NTRK3 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033035 in the retina with a confidence of 0.725035162 (NS-Forest FBeta value). giant bipolar cell + @@ -132114,6 +133556,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set UTRN, NTRK3 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033035 in the retina with a confidence of 0.725035162 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -132148,6 +133596,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set ARHGAP6, ENSG00000278254 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033036 in the retina with a confidence of 0.785018957 (NS-Forest FBeta value). The marker set ENSG00000278254, ERBB4 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033036 in the retina with a confidence of 0.722779636 (NS-Forest FBeta value). OFFx cell + @@ -132169,6 +133618,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel The marker set ENSG00000278254, ERBB4 can identify the Human cell type http://purl.obolibrary.org/obo/CL_4033036 in the retina with a confidence of 0.722779636 (NS-Forest FBeta value). https://doi.org/10.5281/zenodo.11165918 + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -133119,6 +134574,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + @@ -133780,12 +135236,14 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A follicular cell of ovary that differentiates from a cuboidal granulosa cell during the secondary follicle stage. Mural granulosa cells line the inner surface of the follicle wall, surrounding the fluid-filled antral cavity. These cells produce oestrogen during the follicular phase in response to follicle-stimulating hormone (FSH), and progesterone after ovulation in response to luteinizing hormone (LH). + 2024-06-07T12:15:13Z EFO:0005289 MGC mural GC + mural granulosa cell @@ -133845,7 +135303,9 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A(n) B cell that is cycling. + proliferating B cell + cycling B cell @@ -134533,6 +135993,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -134593,6 +136059,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -135004,6 +136476,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023). + 2024-12-11T13:59:19Z @@ -135011,6 +136484,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel limbal stem cell LESC LSC + limbal epithelial stem cell of cornea @@ -135409,8 +136883,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). + 2025-07-22T09:18:18Z + SCG TH/DBH neuron + superior cervical ganglion TH/DBH neuron @@ -135440,8 +136917,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + SCG TH neuron + superior cervical ganglion TH neuron @@ -135471,8 +136951,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker neuropeptide Y (NPY). + 2025-07-22T09:18:18Z + SCG NPY neuron + superior cervical ganglion NPY neuron @@ -135508,8 +136991,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). + 2025-07-22T09:18:18Z + SCG TH/NPY neuron + superior cervical ganglion TH/NPY neuron @@ -135541,8 +137027,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker somatostatin (SST). + 2025-07-22T09:18:18Z + SCG SST neuron + superior cervical ganglion SST neuron @@ -135572,8 +137061,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + SCG VIP neuron + superior cervical ganglion VIP neuron @@ -135604,8 +137096,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker calcitonin gene-related peptide (CGRP). + 2025-07-22T09:18:18Z + SCG CGRP neuron + superior cervical ganglion CGRP neuron @@ -135636,8 +137131,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker dopamine beta-hydroxylase (DBH). + 2025-07-22T09:18:18Z + MCG DBH neuron + middle cervical ganglion DBH neuron @@ -135667,8 +137165,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + MCG TH neuron + middle cervical ganglion TH neuron @@ -135704,8 +137205,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). + 2025-07-22T09:18:18Z + MCG TH/NPY neuron + middle cervical ganglion TH/NPY neuron @@ -135735,8 +137239,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker neuropeptide Y (NPY). + 2025-07-22T09:18:18Z + MCG NPY neuron + middle cervical ganglion NPY neuron @@ -135766,8 +137273,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + MCG VIP neuron + middle cervical ganglion VIP neuron @@ -135797,8 +137307,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker enkephalin. + 2025-07-22T09:18:18Z + stellate ganglion enkephalin neuron + cervicothoracic ganglion enkephalin neuron @@ -135828,8 +137341,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + stellate ganglion TH neuron + cervicothoracic ganglion TH neuron @@ -135865,8 +137381,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). + 2025-07-22T09:18:18Z + stellate ganglion TH/NPY neuron + cervicothoracic ganglion TH/NPY neuron @@ -135896,8 +137415,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + stellate ganglion VIP neuron + cervicothoracic ganglion VIP neuron @@ -135927,8 +137449,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). + 2025-07-22T09:18:18Z + stellate ganglion VAChT neuron + cervicothoracic ganglion VAChT neuron @@ -135958,8 +137483,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker enkephalin. + 2025-07-22T09:18:18Z + thoracic ganglion enkephalin neuron @@ -135989,8 +137516,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + thoracic ganglion TH neuron @@ -136026,8 +137555,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). + 2025-07-22T09:18:18Z + thoracic ganglion TH/NPY neuron @@ -136063,8 +137594,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + lumbar ganglion VIP neuron @@ -136100,8 +137633,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker somatostatin (SST) and tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + lumbar ganglion SST/TH neuron @@ -136137,8 +137672,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). + 2025-07-22T09:18:18Z + lumbar ganglion TH/NPY neuron @@ -136168,8 +137705,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + lumbar ganglion TH neuron @@ -136199,8 +137738,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker neuropeptide Y (NPY). + 2025-07-22T09:18:18Z + lumbar ganglion NPY neuron @@ -136230,8 +137771,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the sacral ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + sacral ganglion TH neuron @@ -136247,7 +137790,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136266,15 +137809,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the lower airway ganglion and expresses the marker choline O-acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP). + A parasympathetic neuron that has the soma located in the lower airway ganglion and expresses the marker choline O-acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + lower airway ganglion ChAT/VIP neuron - A peripheral nervous system neuron that has the soma located in the lower airway ganglion and expresses the marker choline O-acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP). + A parasympathetic neuron that has the soma located in the lower airway ganglion and expresses the marker choline O-acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP). FBC:Autogenerated doi:10.1111/j.1749-6632.1996.tb17547.x @@ -136298,8 +137843,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + CG VIP neuron + celiac ganglion VIP neuron @@ -136323,9 +137871,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker peptide histidine isoleucine (PHI). + 2025-07-22T09:18:18Z + CG PHI neuron + celiac ganglion PHI neuron @@ -136356,8 +137913,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker calcitonin gene-related peptide (CGRP). + 2025-07-22T09:18:18Z + CG CGRP neuron + celiac ganglion CGRP neuron @@ -136382,9 +137942,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker substance P (SP). + 2025-07-22T09:18:18Z + CG SP neuron + celiac ganglion SP neuron @@ -136416,8 +137985,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker somatostatin (SOM). + 2025-07-22T09:18:18Z + CG SOM neuron + celiac ganglion SOM neuron @@ -136454,8 +138026,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker somatostatin (SOM) and calcitonin gene-related peptide (CGRP). + 2025-07-22T09:18:18Z + CG SOM/CGRP neuron + celiac ganglion SOM/CGRP neuron @@ -136479,9 +138054,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + A sympathetic neuron that has the soma located in the superior mesenteric ganglion and expresses the marker substance P (SP). + 2025-07-22T09:18:18Z + SMG SP neuron + superior mesenteric ganglion SP neuron @@ -136511,8 +138095,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sympathetic neuron that has the soma located in the inferior mesenteric ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + IMG TH neuron + inferior mesenteric ganglion TH neuron @@ -136535,9 +138122,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + A sympathetic neuron that has the soma located in the inferior mesenteric ganglion and expresses the marker substance P (SP). + 2025-07-22T09:18:18Z + IMG SP neuron + inferior mesenteric ganglion SP neuron @@ -136553,7 +138149,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136566,15 +138162,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the otic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + A parasympathetic neuron that has the soma located in the otic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + 2025-07-22T09:18:18Z + otic ganglion nNOS neuron - A peripheral nervous system neuron that has the soma located in the otic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + A parasympathetic neuron that has the soma located in the otic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). FBC:Autogenerated doi:10.1002/ar.21516 doi:10.1016/S0006-8993(99)01260-3 @@ -136585,7 +138183,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136598,15 +138196,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the otic ganglion and expresses the marker vasoactive intestinal peptide (VIP). + A parasympathetic neuron that has the soma located in the otic ganglion and expresses the marker vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + otic ganglion VIP neuron - A peripheral nervous system neuron that has the soma located in the otic ganglion and expresses the marker vasoactive intestinal peptide (VIP). + A parasympathetic neuron that has the soma located in the otic ganglion and expresses the marker vasoactive intestinal peptide (VIP). FBC:Autogenerated doi:10.1016/S0006-8993(99)01260-3 @@ -136616,7 +138216,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136629,17 +138229,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the ciliary ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). + A parasympathetic postganglionic neuron whose soma is located in the ciliary ganglion and that co-expresses vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI, both encoded by the VIP gene). This neuron provides parasympathetic innervation to the eye, contributing to regulation of pupillary constriction and ciliary muscle accommodation. It has been identified in human ciliary ganglia by immunohistochemistry (Kiyokawa et al. 2012, PMID:22095632). VIP/PHI co-expression distinguishes this subpopulation from other cholinergic parasympathetic neurons in the ciliary ganglion and is characteristic of a subset of cranial parasympathetic neurons in humans and other mammals. - 2025-07-22T09:18:18Z + 2026-03-13T11:13:54Z + ciliary ganglion VIP-PHI neuron ciliary ganglion VIP/PHI neuron - A peripheral nervous system neuron that has the soma located in the ciliary ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). - FBC:Autogenerated - doi:10.1002/ar.21516 + A parasympathetic postganglionic neuron whose soma is located in the ciliary ganglion and that co-expresses vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI, both encoded by the VIP gene). This neuron provides parasympathetic innervation to the eye, contributing to regulation of pupillary constriction and ciliary muscle accommodation. It has been identified in human ciliary ganglia by immunohistochemistry (Kiyokawa et al. 2012, PMID:22095632). VIP/PHI co-expression distinguishes this subpopulation from other cholinergic parasympathetic neurons in the ciliary ganglion and is characteristic of a subset of cranial parasympathetic neurons in humans and other mammals. + 10.1002/ar.21516 @@ -136647,7 +138247,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136660,15 +138260,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the ciliary ganglion and expresses the marker tyrosine hydroxylase (TH). + A parasympathetic neuron that has the soma located in the ciliary ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + ciliary ganglion TH neuron - A peripheral nervous system neuron that has the soma located in the ciliary ganglion and expresses the marker tyrosine hydroxylase (TH). + A parasympathetic neuron that has the soma located in the ciliary ganglion and expresses the marker tyrosine hydroxylase (TH). FBC:Autogenerated doi:10.1002/ar.21516 doi:10.1016/0006-8993(95)00299-6 @@ -136679,7 +138281,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136692,15 +138294,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the submandibular ganglion and expresses the marker tyrosine hydroxylase (TH). + A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + submandibular ganglion TH cholinergic neuron - A peripheral nervous system neuron that has the soma located in the submandibular ganglion and expresses the marker tyrosine hydroxylase (TH). + A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker tyrosine hydroxylase (TH). FBC:Autogenerated doi:10.1002/ar.21516 @@ -136710,7 +138314,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136723,15 +138327,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the submandibular ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). + A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). + 2025-07-22T09:18:18Z + submandibular ganglion VIP/PHI neuron - A peripheral nervous system neuron that has the soma located in the submandibular ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). + A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). FBC:Autogenerated doi:10.1002/ar.21516 @@ -136741,7 +138347,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136754,15 +138360,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the submandibular ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + 2025-07-22T09:18:18Z + submandibular ganglion nNOS neuron - A peripheral nervous system neuron that has the soma located in the submandibular ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). FBC:Autogenerated doi:10.1002/ar.21516 @@ -136772,7 +138380,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136785,15 +138393,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). + A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). + 2025-07-22T09:18:18Z + sphenopalatine ganglion VIP/PHI neuron + pterygopalatine ganglion VIP/PHI neuron - A peripheral nervous system neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). + A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). FBC:Autogenerated doi:10.1002/ar.21516 @@ -136803,7 +138414,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136816,15 +138427,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP). + A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + sphenopalatine ganglion VIP neuron + pterygopalatine ganglion VIP neuron - A peripheral nervous system neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP). + A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP). FBC:Autogenerated doi:10.1016/S0006-8993(99)01260-3 @@ -136834,7 +138448,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -136847,15 +138461,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pterygopalatine ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + 2025-07-22T09:18:18Z + sphenopalatine ganglion nNOS neuron + pterygopalatine ganglion nNOS neuron - A peripheral nervous system neuron that has the soma located in the pterygopalatine ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). FBC:Autogenerated doi:10.1002/ar.21516 doi:10.1016/S0006-8993(99)01260-3 @@ -136867,22 +138484,31 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + - A peripheral nervous system neuron that has the soma located in the vestibular ganglion and expresses the marker substance P (SP). + + + + + + + A sensory neuron that has the soma located in the vestibular ganglion and expresses the marker substance P (SP). + 2025-07-22T09:18:18Z + Scarpa's ganglion SP neuron + vestibular ganglion SP neuron - A peripheral nervous system neuron that has the soma located in the vestibular ganglion and expresses the marker substance P (SP). + A sensory neuron that has the soma located in the vestibular ganglion and expresses the marker substance P (SP). FBC:Autogenerated doi:10.3109/00016489609137839 @@ -136907,8 +138533,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the nodose ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). + 2025-07-22T09:18:18Z + inferior vagus X ganglion TRPV1 neuron + nodose ganglion TRPV1 neuron @@ -136939,8 +138568,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the nodose ganglion and expresses the marker purinergic receptor P2X3 (P2X3). + 2025-07-22T09:18:18Z + inferior vagus X ganglion P2X3 neuron + nodose ganglion P2X3 neuron @@ -136971,8 +138603,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the nodose ganglion and expresses the marker transient receptor potential vanilloid 2 (TRPV2). + 2025-07-22T09:18:18Z + inferior vagus X ganglion TRPV2 neuron + nodose ganglion TRPV2 neuron @@ -137003,8 +138638,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the nodose ganglion and expresses the marker parvalbumin (PVALB). + 2025-07-22T09:18:18Z + inferior vagus X ganglion PVALB neuron + nodose ganglion PVALB neuron @@ -137035,8 +138673,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the jugular ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). + 2025-07-22T09:18:18Z + superior vagus X ganglion TRPV1 neuron + jugular ganglion TRPV1 neuron @@ -137067,8 +138708,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the jugular ganglion and expresses the marker transient receptor potential vanilloid 2 (TRPV2). + 2025-07-22T09:18:18Z + superior vagus X ganglion TRPV2 neuron + jugular ganglion TRPV2 neuron @@ -137092,9 +138736,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + A sensory neuron that has the soma located in the jugular ganglion and expresses the marker substance P (SP). + 2025-07-22T09:18:18Z + superior vagus X ganglion SP neuron + jugular ganglion SP neuron @@ -137125,8 +138778,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the jugular ganglion and expresses the marker calcitonin gene-related peptide (CGRP). + 2025-07-22T09:18:18Z + superior vagus X ganglion CGRP neuron + jugular ganglion CGRP neuron @@ -137157,8 +138813,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the jugular ganglion and expresses the marker SPARC-like protein 1 (SPARCL1). + 2025-07-22T09:18:18Z + superior vagus X ganglion SPARCL1 neuron + jugular ganglion SPARCL1 neuron @@ -137189,8 +138848,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). + 2025-07-22T09:18:18Z + geniculate ganglion TRPV1 neuron @@ -137221,8 +138882,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker SPARC-like protein 1 (SPARCL1). + 2025-07-22T09:18:18Z + geniculate ganglion SPARCL1 neuron @@ -137253,8 +138916,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker vesicular glutamate transporter 2 (VGLUT2). + 2025-07-22T09:18:18Z + geniculate ganglion VGLUT2 neuron @@ -137270,7 +138935,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137283,15 +138948,16 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline O-acetyltransferase (ChAT). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline O-acetyltransferase (ChAT). 2025-07-22T09:18:18Z + cholinergic myenteric neuron of small intestine myenteric ganglion of small intestine ChAT neuron - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline O-acetyltransferase (ChAT). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline O-acetyltransferase (ChAT). FBC:Autogenerated doi:10.1007/s00418-021-02002-y doi:10.1016/j.jcmgh.2023.06.010 @@ -137315,15 +138981,16 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS). 2025-07-22T09:18:18Z + nitrergic myenteric neuron of small intestine myenteric ganglion of small intestine nNOS neuron - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS). FBC:Autogenerated doi:10.1007/s00418-021-02002-y doi:10.1016/j.jcmgh.2023.06.010 @@ -137348,7 +139015,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP). 2025-07-22T09:18:18Z myenteric ganglion of small intestine VIP neuron @@ -137356,7 +139023,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP). FBC:Autogenerated doi:10.1016/j.jcmgh.2023.06.010 @@ -137385,15 +139052,16 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and vasoactive intestinal peptide (VIP). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and vasoactive intestinal peptide (VIP). 2025-07-22T09:18:18Z + spiny type I neuron of small intestinal myenteric ganglion myenteric ganglion of small intestine nNOS/VIP neuron - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and vasoactive intestinal peptide (VIP). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and vasoactive intestinal peptide (VIP). 10.1007/s00418-005-0107-8 FBC:Autogenerated doi:10.1007/s00418-021-02002-y @@ -137424,7 +139092,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and choline O-acetyltransferase (ChAT). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and choline O-acetyltransferase (ChAT). 2025-07-22T09:18:18Z myenteric ganglion of small intestine nNOS/ChAT neuron @@ -137432,7 +139100,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and choline O-acetyltransferase (ChAT). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and choline O-acetyltransferase (ChAT). FBC:Autogenerated doi:10.1007/s00418-021-02002-y doi:10.1007/s00441-009-0852-4 @@ -137453,7 +139121,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137468,15 +139136,23 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline acetyltransferase (ChAT), calreticulin (CALR), somatostatin (SOM), and substance P (SP). + + + + + + + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline acetyltransferase (ChAT), calretinin (CALR), somatostatin (SOM), and substance P (SP). 2025-07-22T09:18:18Z + Dogiel type II neuron of small intestinal myenteric ganglion + myenteric IPAN of small intestine myenteric ganglion of small intestine ChAT/CALR/SOM/SP neuron - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline acetyltransferase (ChAT), calreticulin (CALR), somatostatin (SOM), and substance P (SP). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline acetyltransferase (ChAT), calretinin (CALR), somatostatin (SOM), and substance P (SP). FBC:Autogenerated doi:10.1007/s00418-007-0335-1 doi:10.1007/s00418-021-02002-y @@ -137506,7 +139182,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP) and galanin (GAL). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP) and galanin (GAL). 2025-07-22T09:18:18Z myenteric ganglion of small intestine VIP/GAL neuron @@ -137514,7 +139190,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP) and galanin (GAL). + An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP) and galanin (GAL). FBC:Autogenerated doi:10.1159/000320542 @@ -137524,7 +139200,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137537,15 +139213,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH). + A sympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + pelvic ganglion TH neuron - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH). + A sympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH). FBC:Autogenerated doi:10.1016/j.eururo.2005.02.010 doi:10.1111/j.1469-7580.2009.01071.x @@ -137557,7 +139235,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137576,15 +139254,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). + A sympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). + 2025-07-22T09:18:18Z + pelvic ganglion TH/DBH neuron - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). + A sympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). FBC:Autogenerated doi:10.1007/s00441-020-03279-6 @@ -137594,7 +139274,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137607,15 +139287,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). + 2025-07-22T09:18:18Z + pelvic ganglion VAChT neuron - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). FBC:Autogenerated doi:10.1111/j.1469-7580.2009.01071.x @@ -137625,7 +139307,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137638,15 +139320,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + 2025-07-22T09:18:18Z + pelvic ganglion nNOS neuron - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). FBC:Autogenerated doi:10.1002/(SICI)1520-6777(2000)19:2%3C185::AID-NAU9%3E3.0.CO;2-2 doi:10.1186/s12894-018-0369-9 @@ -137657,7 +139341,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137676,15 +139360,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase (nNOS) 1 and vasoactive intestinal peptide (VIP). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase (nNOS) 1 and vasoactive intestinal peptide (VIP). + 2025-07-22T09:18:18Z + pelvic ganglion nNOS/VIP neuron - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase (nNOS) 1 and vasoactive intestinal peptide (VIP). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase (nNOS) 1 and vasoactive intestinal peptide (VIP). FBC:Autogenerated doi:10.1186/s12894-018-0369-9 @@ -137694,7 +139380,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137713,15 +139399,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker neuropeptide Y (NPY) and vesicular acetylcholine transporter (VAChT). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuropeptide Y (NPY) and vesicular acetylcholine transporter (VAChT). + 2025-07-22T09:18:18Z + pelvic ganglion NPY/VAChT neuron - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker neuropeptide Y (NPY) and vesicular acetylcholine transporter (VAChT). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuropeptide Y (NPY) and vesicular acetylcholine transporter (VAChT). FBC:Autogenerated doi:10.1002/(SICI)1520-6777(2000)19:2%3C185::AID-NAU9%3E3.0.CO;2-2 @@ -137731,7 +139419,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -137750,15 +139438,17 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1(nNOS) and vesicular acetylcholine transporter (VAChT). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1(nNOS) and vesicular acetylcholine transporter (VAChT). + 2025-07-22T09:18:18Z + pelvic ganglion nNOS/VAChT neuron - A peripheral nervous system neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1(nNOS) and vesicular acetylcholine transporter (VAChT). + A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1(nNOS) and vesicular acetylcholine transporter (VAChT). FBC:Autogenerated doi:10.1002/(SICI)1520-6777(2000)19:2<185::AID-NAU9>3.0.CO;2-2 @@ -137768,29 +139458,297 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - + - A peripheral nervous system neuron that has the soma located in the ovarian nerve plexus ganglion and expresses the marker tyrosine hydroxylase (TH). + A sympathetic neuron that has the soma located in the ovarian nerve plexus ganglion and expresses the marker tyrosine hydroxylase (TH). + 2025-07-22T09:18:18Z + ovarian nerve plexus ganglion TH neuron - A peripheral nervous system neuron that has the soma located in the ovarian nerve plexus ganglion and expresses the marker tyrosine hydroxylase (TH). + A sympathetic neuron that has the soma located in the ovarian nerve plexus ganglion and expresses the marker tyrosine hydroxylase (TH). FBC:Autogenerated doi:10.1111/joa.12436 + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the pan-sensory transcription factor POU domain, class 4, transcription factor 1 (BRN3A/POU4F1). In humans, BRN3A is expressed by approximately 98% of DRG neurons and serves as a broad marker for the sensory neuron population. + + 2026-03-05T00:00:00Z + DRG BRN3A neuron + dorsal root ganglion BRN3A neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the pan-sensory transcription factor POU domain, class 4, transcription factor 1 (BRN3A/POU4F1). In humans, BRN3A is expressed by approximately 98% of DRG neurons and serves as a broad marker for the sensory neuron population. + PMID:29229553 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker calcitonin gene-related peptide (CGRP). This peptidergic nociceptor subpopulation is involved in neurogenic inflammation and pain signaling. + + 2026-03-05T00:00:00Z + DRG CGRP neuron + dorsal root ganglion CGRP neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker calcitonin gene-related peptide (CGRP). This peptidergic nociceptor subpopulation is involved in neurogenic inflammation and pain signaling. + PMID:10686397 + PMID:29229553 + PMID:31293388 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker endothelin-1 (EDN1). Endothelin signaling in DRG neurons has been demonstrated in rat tissue. + + 2026-03-05T00:00:00Z + DRG EDN1 neuron + dorsal root ganglion EDN1 neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker endothelin-1 (EDN1). Endothelin signaling in DRG neurons has been demonstrated in rat tissue. + PMID:2678100 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker sodium channel protein type 9 subunit alpha (Nav1.7/SCN9A). Nav1.7 accounts for approximately 50% of total sodium channel expression in human DRG and is present in 54-57% of TrkA-positive nociceptors. + + 2026-03-05T00:00:00Z + DRG Nav1.7 neuron + dorsal root ganglion Nav1.7 neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker sodium channel protein type 9 subunit alpha (Nav1.7/SCN9A). Nav1.7 accounts for approximately 50% of total sodium channel expression in human DRG and is present in 54-57% of TrkA-positive nociceptors. + PMID:28853927 + PMID:29229553 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker sodium channel protein type 11 subunit alpha (Nav1.9/SCN11A). Nav1.9 is present in approximately 26% of TrkA-positive human DRG neurons and defines a nociceptor subpopulation. + + 2026-03-05T00:00:00Z + DRG Nav1.9 neuron + dorsal root ganglion Nav1.9 neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker sodium channel protein type 11 subunit alpha (Nav1.9/SCN11A). Nav1.9 is present in approximately 26% of TrkA-positive human DRG neurons and defines a nociceptor subpopulation. + PMID:11972962 + PMID:29229553 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the intermediate filament protein peripherin (PRPH). Peripherin marks small-diameter unmyelinated C-fiber neurons in the DRG. + + 2026-03-05T00:00:00Z + DRG peripherin neuron + dorsal root ganglion peripherin neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the intermediate filament protein peripherin (PRPH). Peripherin marks small-diameter unmyelinated C-fiber neurons in the DRG. + PMID:28853927 + PMID:31293388 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker piezo-type mechanosensitive ion channel component 2 (Piezo2). Piezo2 is the primary mechanotransduction channel and is present in approximately 35% of TrkA-positive human DRG neurons. + + 2026-03-05T00:00:00Z + DRG Piezo2 neuron + dorsal root ganglion Piezo2 neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker piezo-type mechanosensitive ion channel component 2 (Piezo2). Piezo2 is the primary mechanotransduction channel and is present in approximately 35% of TrkA-positive human DRG neurons. + PMID:29229553 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker proto-oncogene tyrosine-protein kinase receptor Ret (RET). RET is present in approximately 46% of TrkA-positive human DRG neurons and marks the non-peptidergic nociceptor population. + + 2026-03-05T00:00:00Z + DRG RET neuron + dorsal root ganglion RET neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker proto-oncogene tyrosine-protein kinase receptor Ret (RET). RET is present in approximately 46% of TrkA-positive human DRG neurons and marks the non-peptidergic nociceptor population. + PMID:29229553 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker protachykinin-1 (substance P). This peptidergic nociceptor subpopulation is involved in pain signaling and neurogenic inflammation. + + 2026-03-05T00:00:00Z + DRG SP neuron + dorsal root ganglion SP neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker protachykinin-1 (substance P). This peptidergic nociceptor subpopulation is involved in pain signaling and neurogenic inflammation. + PMID:10686397 + PMID:31293388 + + + + + + + + + + + + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker transient receptor potential cation channel subfamily V member 1 (TRPV1). TRPV1 is the canonical heat and capsaicin nociceptor marker and is present in approximately 54% of TrkA-positive human DRG neurons. + + 2026-03-05T00:00:00Z + DRG TRPV1 neuron + dorsal root ganglion TRPV1 neuron + + + + + A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker transient receptor potential cation channel subfamily V member 1 (TRPV1). TRPV1 is the canonical heat and capsaicin nociceptor marker and is present in approximately 54% of TrkA-positive human DRG neurons. + PMID:28853927 + PMID:29229553 + + + + @@ -139531,6 +141489,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 2024-10-11T13:25:51Z + The marker set RELN, HCRTR2 can identify the Human cell type PAX6 GABAergic interneuron in the neocortex with a confidence of 0.724125093 (NS-Forest FBeta value). PAX6 GABAergic interneuron @@ -142711,10 +144670,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel A natural killer cell that is part of the uterus, specifically within the endometrium during the non-pregnant state and in the decidua during pregnancy. This cell exhibits dynamic changes in frequency throughout the menstrual cycle, with lower levels during menstruation and a significant increase during the mid-secretory phase and early pregnancy. + 2024-11-15T10:12:40Z endometrial natural killer cell uNK cell + uterine natural killer cell @@ -143392,7 +145353,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + A tuft cell that is part of the epithelium of the urethra. This cell monitors urethral contents by detecting chemical stimuli, such as bitter compounds and sugars. Upon activation, it stimulates sensory nerve fibres and triggers detrusor muscle contraction, likely aiding in pathogen clearance by promoting bladder emptying. @@ -144423,8 +146384,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel An acinar cell of the salivary gland, characterized by a pyramidal or triangular shape with a spherical nucleus and abundant eosinophilic zymogen granules. This cell secretes watery, enzyme‐rich fluid containing α-amylase, proline-rich proteins, and secretory immunoglobulins for starch digestion and antimicrobial defence. In humans and mice, serous acinar cell predominates in the parotid gland and to a lesser extent in the submandibular gland, where it exists alongside mucous acinar cells (Maruyama et al., 2019). + 2025-08-05T15:24:46Z + serous acinar cell of salivary gland @@ -144488,8 +146451,10 @@ In addition to their secretory function, fallopian tube secretory epithelial cel An acinar cell of the salivary gland, with a hybrid seromucous phenotype, co-expressing serous and mucous markers and producing a mixed secretion of enzymes-containing serous fluid and mucins essential for lubrication, digestion, and antimicrobial defense. Predominant in the submandibular glands of humans and mice, its differentiation and secretory gene expression are regulated by FGFR2b–MAPK signaling, driven by paracrine FGF7 from adjacent myoepithelial cells, which provides a key niche signal for seromucous identity. + 2025-08-06T11:26:37Z + seromucous acinar cell of salivary gland @@ -144541,6 +146506,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + @@ -146566,6 +148532,1242 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + + + + + + + + + + + + + A peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). + + 2026-03-13T11:13:54Z + peptidergic nociceptor + cervical dorsal root ganglion CGRP neuron + + + + + A peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). + 10.1016/S0304-3940(00)00772-2 + PMID:29229553 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. + + 2026-03-13T11:13:54Z + cervical dorsal root ganglion Endothelin 1 neuron + EDN1 neuron + cervical dorsal root ganglion endothelin-1 neuron + + + + + A sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. + 10.1073/pnas.86.19.7634 + + + + + + + + + + + + + + + + + + + + + + A nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. + + 2026-03-13T11:13:54Z + cervical dorsal root ganglion Nav1.7 neuron + + + + + A nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. + 10.1007/s12264-017-0132-3 + 10.1038/nn.3602 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. + + 2026-03-13T11:13:54Z + cervical dorsal root ganglion Nav1.9 neuron + + + + + A nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. + 10.1016/S0166-2236(02)02150-1 + 10.1038/nn.3602 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A small-diameter sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. + + 2026-03-13T11:13:54Z + cervical dorsal root ganglion Peripherin neuron + C-fiber neuron + cervical dorsal root ganglion peripherin neuron + + + + + A small-diameter sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. + 10.1007/s12264-017-0132-3 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A mechanosensitive sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. + + 2026-03-13T11:13:54Z + mechanosensitive DRG neuron + cervical dorsal root ganglion Piezo2 neuron + + + + + A mechanosensitive sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A non-peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. + + 2026-03-13T11:13:54Z + non-peptidergic nociceptor + cervical dorsal root ganglion RET neuron + + + + + A non-peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. + + 2026-03-13T11:13:54Z + cervical dorsal root ganglion SP neuron + SP neuron + cervical dorsal root ganglion substance P neuron + + + + + A peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. + 10.1016/S0304-3940(00)00772-2 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A polymodal nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. + + 2026-03-13T11:13:54Z + capsaicin-sensitive nociceptor + cervical dorsal root ganglion TRPV1 neuron + + + + + A polymodal nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. + 10.1007/s12264-017-0132-3 + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + A catecholaminergic neuron whose soma is located in an intrinsic cardiac ganglion and that expresses tyrosine hydroxylase (TH, encoded by TH), the rate-limiting enzyme in catecholamine biosynthesis. This neuron constitutes a minor subpopulation within the predominantly cholinergic parasympathetic intrinsic cardiac nervous system, identified in adult human cardiac ganglia by immunohistochemistry (Singh et al. 1999, PMID:9918529; Kawano et al. 2003, DOI:10.1007/s003800300005). It participates in local cardiac autonomic regulation, including modulation of heart rate and contractility. Its catecholaminergic phenotype distinguishes it from the majority cholinergic neurons of the same ganglia. + + 2026-03-13T11:13:54Z + catecholaminergic intrinsic cardiac neuron + intrinsic cardiac ganglion TH neuron + + + + + A catecholaminergic neuron whose soma is located in an intrinsic cardiac ganglion and that expresses tyrosine hydroxylase (TH, encoded by TH), the rate-limiting enzyme in catecholamine biosynthesis. This neuron constitutes a minor subpopulation within the predominantly cholinergic parasympathetic intrinsic cardiac nervous system, identified in adult human cardiac ganglia by immunohistochemistry (Singh et al. 1999, PMID:9918529; Kawano et al. 2003, DOI:10.1007/s003800300005). It participates in local cardiac autonomic regulation, including modulation of heart rate and contractility. Its catecholaminergic phenotype distinguishes it from the majority cholinergic neurons of the same ganglia. + 10.1007/s003800300005 + PMID:9918529 + + + + + + + + + + + + + + + + + + + + + + A peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). + + 2026-03-13T11:13:54Z + peptidergic nociceptor + lumbar dorsal root ganglion CGRP neuron + + + + + A peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). + 10.1016/S0304-3940(00)00772-2 + PMID:29229553 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. + + 2026-03-13T11:13:54Z + lumbar dorsal root ganglion Endothelin 1 neuron + EDN1 neuron + lumbar dorsal root ganglion endothelin-1 neuron + + + + + A sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. + 10.1073/pnas.86.19.7634 + + + + + + + + + + + + + + + + + + + + + + A nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. + + 2026-03-13T11:13:54Z + lumbar dorsal root ganglion Nav1.7 neuron + + + + + A nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. + 10.1007/s12264-017-0132-3 + 10.1038/nn.3602 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. + + 2026-03-13T11:13:54Z + lumbar dorsal root ganglion Nav1.9 neuron + + + + + A nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. + 10.1016/S0166-2236(02)02150-1 + 10.1038/nn.3602 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A small-diameter sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. + + 2026-03-13T11:13:54Z + lumbar dorsal root ganglion Peripherin neuron + C-fiber neuron + lumbar dorsal root ganglion peripherin neuron + + + + + A small-diameter sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. + 10.1007/s12264-017-0132-3 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A mechanosensitive sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. + + 2026-03-13T11:13:54Z + mechanosensitive DRG neuron + lumbar dorsal root ganglion Piezo2 neuron + + + + + A mechanosensitive sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A non-peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. + + 2026-03-13T11:13:54Z + non-peptidergic nociceptor + lumbar dorsal root ganglion RET neuron + + + + + A non-peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. + + 2026-03-13T11:13:54Z + lumbar dorsal root ganglion SP neuron + SP neuron + lumbar dorsal root ganglion substance P neuron + + + + + A peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. + 10.1016/S0304-3940(00)00772-2 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A polymodal nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. + + 2026-03-13T11:13:54Z + capsaicin-sensitive nociceptor + lumbar dorsal root ganglion TRPV1 neuron + + + + + A polymodal nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. + 10.1007/s12264-017-0132-3 + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). + + 2026-03-13T11:13:54Z + peptidergic nociceptor + sacral dorsal root ganglion CGRP neuron + + + + + A peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). + 10.1016/S0304-3940(00)00772-2 + PMID:29229553 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. + + 2026-03-13T11:13:54Z + sacral dorsal root ganglion Endothelin 1 neuron + EDN1 neuron + sacral dorsal root ganglion endothelin-1 neuron + + + + + A sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. + 10.1073/pnas.86.19.7634 + + + + + + + + + + + + + + + + + + + + + + A nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. + + 2026-03-13T11:13:54Z + sacral dorsal root ganglion Nav1.7 neuron + + + + + A nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. + 10.1007/s12264-017-0132-3 + 10.1038/nn.3602 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. + + 2026-03-13T11:13:54Z + sacral dorsal root ganglion Nav1.9 neuron + + + + + A nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. + 10.1016/S0166-2236(02)02150-1 + 10.1038/nn.3602 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A small-diameter sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. + + 2026-03-13T11:13:54Z + sacral dorsal root ganglion Peripherin neuron + C-fiber neuron + sacral dorsal root ganglion peripherin neuron + + + + + A small-diameter sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. + 10.1007/s12264-017-0132-3 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A mechanosensitive sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. + + 2026-03-13T11:13:54Z + mechanosensitive DRG neuron + sacral dorsal root ganglion Piezo2 neuron + + + + + A mechanosensitive sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A non-peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. + + 2026-03-13T11:13:54Z + non-peptidergic nociceptor + sacral dorsal root ganglion RET neuron + + + + + A non-peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. + + 2026-03-13T11:13:54Z + sacral dorsal root ganglion SP neuron + SP neuron + sacral dorsal root ganglion substance P neuron + + + + + A peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. + 10.1016/S0304-3940(00)00772-2 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A polymodal nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. + + 2026-03-13T11:13:54Z + capsaicin-sensitive nociceptor + sacral dorsal root ganglion TRPV1 neuron + + + + + A polymodal nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. + 10.1007/s12264-017-0132-3 + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). + + 2026-03-13T11:13:54Z + peptidergic nociceptor + thoracic dorsal root ganglion CGRP neuron + + + + + A peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). + 10.1016/S0304-3940(00)00772-2 + PMID:29229553 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. + + 2026-03-13T11:13:54Z + thoracic dorsal root ganglion Endothelin 1 neuron + EDN1 neuron + thoracic dorsal root ganglion endothelin-1 neuron + + + + + A sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. + 10.1073/pnas.86.19.7634 + + + + + + + + + + + + + + + + + + + + + + A nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. + + 2026-03-13T11:13:54Z + thoracic dorsal root ganglion Nav1.7 neuron + + + + + A nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. + 10.1007/s12264-017-0132-3 + 10.1038/nn.3602 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. + + 2026-03-13T11:13:54Z + thoracic dorsal root ganglion Nav1.9 neuron + + + + + A nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. + 10.1016/S0166-2236(02)02150-1 + 10.1038/nn.3602 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A small-diameter sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. + + 2026-03-13T11:13:54Z + thoracic dorsal root ganglion Peripherin neuron + C-fiber neuron + thoracic dorsal root ganglion peripherin neuron + + + + + A small-diameter sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. + 10.1007/s12264-017-0132-3 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A mechanosensitive sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. + + 2026-03-13T11:13:54Z + mechanosensitive DRG neuron + thoracic dorsal root ganglion Piezo2 neuron + + + + + A mechanosensitive sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A non-peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. + + 2026-03-13T11:13:54Z + non-peptidergic nociceptor + thoracic dorsal root ganglion RET neuron + + + + + A non-peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + + + + + + + + + + + + + + + + + + + A peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. + + 2026-03-13T11:13:54Z + thoracic dorsal root ganglion SP neuron + SP neuron + thoracic dorsal root ganglion substance P neuron + + + + + A peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. + 10.1016/S0304-3940(00)00772-2 + PMID:31293388 + + + + + + + + + + + + + + + + + + + + + + A polymodal nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. + + 2026-03-13T11:13:54Z + capsaicin-sensitive nociceptor + thoracic dorsal root ganglion TRPV1 neuron + + + + + A polymodal nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. + 10.1007/s12264-017-0132-3 + 10.1016/j.neuroscience.2017.11.047 + PMID:29229553 + + + + @@ -149812,7 +153014,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.22 - + Location assignment based on CCF broad region. @@ -149820,7 +153022,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF acronym region. @@ -149828,7 +153030,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.25 - + Location assignment based on CCF acronym region. @@ -149836,7 +153038,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF acronym region. @@ -149844,7 +153046,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF broad region. @@ -149852,7 +153054,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.42 - + Location assignment based on CCF broad region. @@ -149860,7 +153062,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF broad region. @@ -149918,7 +153120,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -149943,7 +153145,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel https://knowledge.brain-map.org/abcatlas#AQIBQVA4Sk5ONUxZQUJHVk1HS1kxQgACUTFOQ1dXUEc2RlowRE5JWEpCUQADBAFGUzAwRFhWMFQ5UjFYOUZKNFFFAAIBMjUgUGluZWFsIEdsdXQAAAFRWTVTOEtNTzVITEpVRjBQMDBLAAIAAAExNUJLNDdEQ0lPRjFTTExVVzlQAAIAAAFDQkdDMFUzMFZWOUpQUjYwVEpVAAIAAAQBAQKBrMaOgZYVIAOEak39hFgYTQAFAAYBAQJGUzAwRFhWMFQ5UjFYOUZKNFFFAAN%2BAAAABAAACEc0STRHRkpYSkI5QVRaM1BUWDEACUxWREJKQVc4Qkk1WVNTMVFVQkcACgALAW5vbmUAAm5vbmUAAwEEAQACIzAwMDAwMAADyAEABQEBAiMwMDAwMDAAA8gBAAAAAUs5Sk4yM1AyNEtRQ0dLOVU3NUEAAkhTWVpQWlcxNjY5VTgyMUJXWVAAAwQBRlMwMERYVjBUOVIxWDlGSjRRRQACATI1IFBpbmVhbCBHbHV0AAABUVk1UzhLTU81SExKVUYwUDAwSwACAAABMTVCSzQ3RENJT0YxU0xMVVc5UAACAAABQ0JHQzBVMzBWVjlKUFI2MFRKVQACAAAEAQAChFC%2FH4OCCX8DhKAah4TEPdkEMk5RVElFN1RBTVA4UFFBSE80UAAFga%2BmSoHprA6BoIFHgJLV6AYABwAABQAGAQECRlMwMERYVjBUOVIxWDlGSjRRRQADfgAAAAQAAAhWRk9GWVBGUUdSS1VEUVVaM0ZGAAlMVkRCSkFXOEJJNVlTUzFRVUJHAAoACwFUTE9LV0NMOTVSVTAzRDlQRVRHAAI3M0dWVERYREVHRTI3TTJYSk1UAAMBBAEAAiMwMDAwMDAAA8gBAAUBAQIjMDAwMDAwAAPIAQAAAAIDAA%3D%3D https://purl.brain-bican.org/taxonomy/CCN20230722/CS20230722_CLAS_25.h5ad - + @@ -149958,7 +153160,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + Inferred to be glutamate secretion, neurotransmission based on expression of Ddc, Slc17a6, Slc17a7 @@ -149966,7 +153168,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.38 - + Location assignment based on CCF acronym region. @@ -149974,7 +153176,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. @@ -150063,7 +153265,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF acronym region. @@ -150071,7 +153273,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.44 - + Location assignment based on CCF broad region. @@ -150079,7 +153281,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.25 - + Location assignment based on CCF broad region. @@ -150087,7 +153289,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.16 - + Location assignment based on CCF acronym region. @@ -150095,7 +153297,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.44 - + Location assignment based on CCF acronym region. @@ -150103,7 +153305,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.31 - + Location assignment based on CCF broad region. @@ -150182,7 +153384,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.76 - + Location assignment based on CCF broad region. @@ -150190,7 +153392,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF acronym region. @@ -150198,7 +153400,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF acronym region. @@ -150206,7 +153408,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF acronym region. @@ -150214,7 +153416,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -150301,7 +153503,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.69 - + Location assignment based on CCF broad region. @@ -150309,7 +153511,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.31 - + Location assignment based on CCF broad region. @@ -150393,7 +153595,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.73 - + Location assignment based on CCF broad region. @@ -150401,7 +153603,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.27 - + Location assignment based on CCF broad region. @@ -150486,7 +153688,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.65 - + Location assignment based on CCF broad region. @@ -150494,7 +153696,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF acronym region. @@ -150502,7 +153704,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.34 - + Location assignment based on CCF broad region. @@ -150578,7 +153780,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.32 - + Location assignment based on CCF broad region. @@ -150586,7 +153788,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF acronym region. @@ -150594,7 +153796,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.57 - + Location assignment based on CCF broad region. @@ -150670,7 +153872,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.12 - + Location assignment based on CCF broad region. @@ -150678,7 +153880,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -150686,7 +153888,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.56 - + Location assignment based on CCF broad region. @@ -150762,7 +153964,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.26 - + Location assignment based on CCF broad region. @@ -150770,7 +153972,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.16 - + Location assignment based on CCF acronym region. @@ -150778,7 +153980,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.51 - + Location assignment based on CCF broad region. @@ -150855,7 +154057,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.12 - + Location assignment based on CCF broad region. @@ -150863,7 +154065,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF acronym region. @@ -150871,7 +154073,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF broad region. @@ -150879,7 +154081,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.48 - + Location assignment based on CCF broad region. @@ -150956,7 +154158,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -150964,7 +154166,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.21 - + Location assignment based on CCF broad region. @@ -150972,7 +154174,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF acronym region. @@ -150980,7 +154182,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.58 - + Location assignment based on CCF broad region. @@ -151060,7 +154262,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.35 - + Location assignment based on CCF acronym region. @@ -151068,7 +154270,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF acronym region. @@ -151076,7 +154278,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.18 - + Location assignment based on CCF acronym region. @@ -151084,7 +154286,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.5 - + Location assignment based on CCF broad region. @@ -151092,7 +154294,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.3 - + Location assignment based on CCF broad region. @@ -151100,7 +154302,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF acronym region. @@ -151108,7 +154310,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -151185,7 +154387,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF acronym region. @@ -151193,7 +154395,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.56 - + Location assignment based on CCF broad region. @@ -151201,7 +154403,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF broad region. @@ -151209,7 +154411,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -151285,7 +154487,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF acronym region. @@ -151293,7 +154495,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.91 - + Location assignment based on CCF broad region. @@ -151301,7 +154503,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF acronym region. @@ -151377,7 +154579,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.19 - + Location assignment based on CCF broad region. @@ -151385,7 +154587,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.35 - + Location assignment based on CCF broad region. @@ -151393,7 +154595,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.27 - + Location assignment based on CCF broad region. @@ -151471,7 +154673,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF acronym region. @@ -151479,7 +154681,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.33 - + Location assignment based on CCF broad region. @@ -151487,7 +154689,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.26 - + Location assignment based on CCF broad region. @@ -151495,7 +154697,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF acronym region. @@ -151503,7 +154705,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.22 - + Location assignment based on CCF broad region. @@ -151579,7 +154781,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.23 - + Location assignment based on CCF broad region. @@ -151587,7 +154789,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF broad region. @@ -151595,7 +154797,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.55 - + Location assignment based on CCF broad region. @@ -151671,7 +154873,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF broad region. @@ -151679,7 +154881,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -151687,7 +154889,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.42 - + Location assignment based on CCF broad region. @@ -151761,7 +154963,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.67 - + Location assignment based on CCF broad region. @@ -151814,7 +155016,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -151833,14 +155035,14 @@ In addition to their secretory function, fallopian tube secretory epithelial cel https://knowledge.brain-map.org/abcatlas#AQIBQVA4Sk5ONUxZQUJHVk1HS1kxQgACUTFOQ1dXUEc2RlowRE5JWEpCUQADBAFGUzAwRFhWMFQ5UjFYOUZKNFFFAAIAAAFRWTVTOEtNTzVITEpVRjBQMDBLAAIAAAExNUJLNDdEQ0lPRjFTTExVVzlQAAIAAAFDQkdDMFUzMFZWOUpQUjYwVEpVAAIBNTIyMSBBc3Ryby1URSBOTl8xAAAEAQECgazGjoGWFSADhGpN%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%2BAAAABAAACFZGT0ZZUEZRR1JLVURRVVozRkYACUxWREJKQVc4Qkk1WVNTMVFVQkcACgALAVRMT0tXQ0w5NVJVMDNEOVBFVEcAAjczR1ZURFhERUdFMjdNMlhKTVQAAwEEAQACIzAwMDAwMAADyAEABQEBAiMwMDAwMDAAA8gBAAAAAgMA https://purl.brain-bican.org/taxonomy/CCN20230722/CS20230722_CLAS_30.h5ad - + - + Inferred to be glutamate secretion, neurotransmission based on expression of Aldh1a1, Slc17a7 @@ -151848,7 +155050,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.19 - + Location assignment based on CCF broad region. @@ -151856,7 +155058,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.76 - + Location assignment based on CCF broad region. @@ -151934,7 +155136,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.19 - + Location assignment based on CCF acronym region. @@ -151942,7 +155144,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.19 - + Location assignment based on CCF acronym region. @@ -151950,7 +155152,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.97 - + Location assignment based on CCF broad region. @@ -151958,7 +155160,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF acronym region. @@ -151966,7 +155168,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.27 - + Location assignment based on CCF acronym region. @@ -152043,7 +155245,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.26 - + Location assignment based on CCF acronym region. @@ -152051,7 +155253,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF acronym region. @@ -152059,7 +155261,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -152067,7 +155269,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.27 - + Location assignment based on CCF acronym region. @@ -152144,7 +155346,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -152152,7 +155354,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.32 - + Location assignment based on CCF broad region. @@ -152160,7 +155362,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.13 - + Location assignment based on CCF broad region. @@ -152168,7 +155370,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF broad region. @@ -152243,7 +155445,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.71 - + Location assignment based on CCF broad region. @@ -152251,7 +155453,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -152328,7 +155530,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.29 - + Location assignment based on CCF acronym region. @@ -152336,7 +155538,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.39 - + Location assignment based on CCF broad region. @@ -152344,7 +155546,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.3 - + Location assignment based on CCF broad region. @@ -152352,7 +155554,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.19 - + Location assignment based on CCF broad region. @@ -152429,7 +155631,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.7 - + Location assignment based on CCF broad region. @@ -152437,7 +155639,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -152445,7 +155647,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF acronym region. @@ -152453,7 +155655,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.7 - + Location assignment based on CCF acronym region. @@ -152531,7 +155733,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.13 - + Location assignment based on CCF acronym region. @@ -152539,7 +155741,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF acronym region. @@ -152547,7 +155749,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.25 - + Location assignment based on CCF broad region. @@ -152555,7 +155757,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.55 - + Location assignment based on CCF broad region. @@ -152634,7 +155836,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF acronym region. @@ -152642,7 +155844,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.19 - + Location assignment based on CCF acronym region. @@ -152650,7 +155852,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.39 - + Location assignment based on CCF broad region. @@ -152658,7 +155860,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.13 - + Location assignment based on CCF acronym region. @@ -152666,7 +155868,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF acronym region. @@ -152674,7 +155876,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.58 - + Location assignment based on CCF broad region. @@ -152753,7 +155955,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.12 - + Location assignment based on CCF broad region. @@ -152761,7 +155963,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.3 - + Location assignment based on CCF broad region. @@ -152769,7 +155971,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF acronym region. @@ -152777,7 +155979,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.3 - + Location assignment based on CCF acronym region. @@ -152785,7 +155987,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.39 - + Location assignment based on CCF acronym region. @@ -152793,7 +155995,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.43 - + Location assignment based on CCF broad region. @@ -152869,7 +156071,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF acronym region. @@ -152877,7 +156079,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.32 - + Location assignment based on CCF broad region. @@ -152885,7 +156087,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.64 - + Location assignment based on CCF broad region. @@ -152962,7 +156164,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.31 - + Location assignment based on CCF acronym region. @@ -152970,7 +156172,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.26 - + Location assignment based on CCF acronym region. @@ -152978,7 +156180,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.44 - + Location assignment based on CCF broad region. @@ -152986,7 +156188,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.56 - + Location assignment based on CCF broad region. @@ -153063,7 +156265,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF acronym region. @@ -153071,7 +156273,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF acronym region. @@ -153079,7 +156281,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.44 - + Location assignment based on CCF broad region. @@ -153087,7 +156289,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.51 - + Location assignment based on CCF broad region. @@ -153164,7 +156366,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.29 - + Location assignment based on CCF acronym region. @@ -153172,7 +156374,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.29 - + Location assignment based on CCF acronym region. @@ -153180,7 +156382,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF acronym region. @@ -153188,7 +156390,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. @@ -153263,7 +156465,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.63 - + Location assignment based on CCF acronym region. @@ -153271,7 +156473,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -153347,7 +156549,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.52 - + Location assignment based on CCF acronym region. @@ -153355,7 +156557,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.84 - + Location assignment based on CCF broad region. @@ -153363,7 +156565,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.16 - + Location assignment based on CCF acronym region. @@ -153440,7 +156642,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.58 - + Location assignment based on CCF acronym region. @@ -153448,7 +156650,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.24 - + Location assignment based on CCF acronym region. @@ -153456,7 +156658,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.88 - + Location assignment based on CCF broad region. @@ -153532,7 +156734,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.34 - + Location assignment based on CCF broad region. @@ -153540,7 +156742,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.34 - + Location assignment based on CCF acronym region. @@ -153548,7 +156750,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.61 - + Location assignment based on CCF broad region. @@ -153602,7 +156804,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -153621,7 +156823,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel https://knowledge.brain-map.org/abcatlas#AQIBQVA4Sk5ONUxZQUJHVk1HS1kxQgACUTFOQ1dXUEc2RlowRE5JWEpCUQADBAFGUzAwRFhWMFQ5UjFYOUZKNFFFAAIAAAFRWTVTOEtNTzVITEpVRjBQMDBLAAIAAAExNUJLNDdEQ0lPRjFTTExVVzlQAAIAAAFDQkdDMFUzMFZWOUpQUjYwVEpVAAIBNTI0NSBUYW55Y3l0ZSBOTl8yAAAEAQECgazGjoGWFSADhGpN%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%2BAAAABAAACFZGT0ZZUEZRR1JLVURRVVozRkYACUxWREJKQVc4Qkk1WVNTMVFVQkcACgALAVRMT0tXQ0w5NVJVMDNEOVBFVEcAAjczR1ZURFhERUdFMjdNMlhKTVQAAwEEAQACIzAwMDAwMAADyAEABQEBAiMwMDAwMDAAA8gBAAAAAgMA https://purl.brain-bican.org/taxonomy/CCN20230722/CS20230722_CLAS_30.h5ad - + @@ -153634,7 +156836,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + Inferred to be glutamate secretion, neurotransmission based on expression of Slc17a8 @@ -153642,7 +156844,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.92 - + Location assignment based on CCF broad region. @@ -153650,7 +156852,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.88 - + Location assignment based on CCF acronym region. @@ -153729,7 +156931,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.73 - + Location assignment based on CCF broad region. @@ -153737,7 +156939,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.47 - + Location assignment based on CCF acronym region. @@ -153745,7 +156947,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.24 - + Location assignment based on CCF acronym region. @@ -153753,7 +156955,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF acronym region. @@ -153761,7 +156963,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.27 - + Location assignment based on CCF broad region. @@ -153838,7 +157040,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.94 - + Location assignment based on CCF broad region. @@ -153846,7 +157048,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.29 - + Location assignment based on CCF acronym region. @@ -153854,7 +157056,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.6 - + Location assignment based on CCF acronym region. @@ -153931,7 +157133,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.69 - + Location assignment based on CCF broad region. @@ -153939,7 +157141,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.69 - + Location assignment based on CCF acronym region. @@ -153947,7 +157149,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.31 - + Location assignment based on CCF acronym region. @@ -153955,7 +157157,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.31 - + Location assignment based on CCF broad region. @@ -154033,7 +157235,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.78 - + Location assignment based on CCF broad region. @@ -154041,7 +157243,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.22 - + Location assignment based on CCF acronym region. @@ -154049,7 +157251,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.76 - + Location assignment based on CCF acronym region. @@ -154057,7 +157259,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.22 - + Location assignment based on CCF broad region. @@ -154137,7 +157339,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.46 - + Location assignment based on CCF acronym region. @@ -154145,7 +157347,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.75 - + Location assignment based on CCF broad region. @@ -154153,7 +157355,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.19 - + Location assignment based on CCF acronym region. @@ -154161,7 +157363,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.29 - + Location assignment based on CCF acronym region. @@ -154169,7 +157371,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.25 - + Location assignment based on CCF broad region. @@ -154257,7 +157459,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.48 - + Location assignment based on CCF acronym region. @@ -154265,7 +157467,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF acronym region. @@ -154273,7 +157475,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.32 - + Location assignment based on CCF broad region. @@ -154281,7 +157483,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.23 - + Location assignment based on CCF acronym region. @@ -154289,7 +157491,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.68 - + Location assignment based on CCF broad region. @@ -154373,7 +157575,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF acronym region. @@ -154381,7 +157583,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.49 - + Location assignment based on CCF acronym region. @@ -154389,7 +157591,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.24 - + Location assignment based on CCF broad region. @@ -154397,7 +157599,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.74 - + Location assignment based on CCF broad region. @@ -154450,7 +157652,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -154470,14 +157672,14 @@ In addition to their secretory function, fallopian tube secretory epithelial cel https://knowledge.brain-map.org/abcatlas#AQIBQVA4Sk5ONUxZQUJHVk1HS1kxQgACUTFOQ1dXUEc2RlowRE5JWEpCUQADBAFGUzAwRFhWMFQ5UjFYOUZKNFFFAAIAAAFRWTVTOEtNTzVITEpVRjBQMDBLAAIAAAExNUJLNDdEQ0lPRjFTTExVVzlQAAIAAAFDQkdDMFUzMFZWOUpQUjYwVEpVAAIBNTI2NSBDSE9SIE5OXzEAAAQBAQKBrMaOgZYVIAOEak39hFgYTQAFAAYBAQJDQkdDMFUzMFZWOUpQUjYwVEpVAAN%2BAAAABAAACEc0STRHRkpYSkI5QVRaM1BUWDEACUxWREJKQVc4Qkk1WVNTMVFVQkcACgALAW5vbmUAAm5vbmUAAwEEAQACIzAwMDAwMAADyAEABQEBAiMwMDAwMDAAA8gBAAAAAUs5Sk4yM1AyNEtRQ0dLOVU3NUEAAkhTWVpQWlcxNjY5VTgyMUJXWVAAAwQBRlMwMERYVjBUOVIxWDlGSjRRRQACAAABUVk1UzhLTU81SExKVUYwUDAwSwACAAABMTVCSzQ3RENJT0YxU0xMVVc5UAACAAABQ0JHQzBVMzBWVjlKUFI2MFRKVQACATUyNjUgQ0hPUiBOTl8xAAAEAQAChFC%2FH4OCCX8DhKAah4TEPdkEMk5RVElFN1RBTVA4UFFBSE80UAAFga%2BmSoHprA6BoIFHgJLV6AYABwAABQAGAQECQ0JHQzBVMzBWVjlKUFI2MFRKVQADfgAAAAQAAAhWRk9GWVBGUUdSS1VEUVVaM0ZGAAlMVkRCSkFXOEJJNVlTUzFRVUJHAAoACwFUTE9LV0NMOTVSVTAzRDlQRVRHAAI3M0dWVERYREVHRTI3TTJYSk1UAAMBBAEAAiMwMDAwMDAAA8gBAAUBAQIjMDAwMDAwAAPIAQAAAAIDAA%3D%3D https://purl.brain-bican.org/taxonomy/CCN20230722/CS20230722_CLAS_30.h5ad - + - + Inferred to be glutamate secretion, neurotransmission based on expression of Slc17a8 @@ -154485,7 +157687,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.18 - + Location assignment based on CCF acronym region. @@ -154493,7 +157695,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.22 - + Location assignment based on CCF acronym region. @@ -154501,7 +157703,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.81 - + Location assignment based on CCF broad region. @@ -154576,7 +157778,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.52 - + Location assignment based on CCF broad region. @@ -154584,7 +157786,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF broad region. @@ -154662,7 +157864,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.21 - + Location assignment based on CCF broad region. @@ -154670,7 +157872,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.13 - + Location assignment based on CCF broad region. @@ -154678,7 +157880,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF broad region. @@ -154686,7 +157888,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -154694,7 +157896,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.23 - + Location assignment based on CCF broad region. @@ -154770,7 +157972,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.53 - + Location assignment based on CCF broad region. @@ -154778,7 +157980,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.12 - + Location assignment based on CCF broad region. @@ -154786,7 +157988,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -154862,7 +158064,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -154870,7 +158072,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF broad region. @@ -154878,7 +158080,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.16 - + Location assignment based on CCF broad region. @@ -154955,7 +158157,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -154963,7 +158165,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.39 - + Location assignment based on CCF broad region. @@ -154971,7 +158173,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -154979,7 +158181,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -155055,7 +158257,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.26 - + Location assignment based on CCF broad region. @@ -155063,7 +158265,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -155138,7 +158340,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.22 - + Location assignment based on CCF broad region. @@ -155146,7 +158348,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -155221,7 +158423,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.33 - + Location assignment based on CCF broad region. @@ -155229,7 +158431,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -155303,7 +158505,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.41 - + Location assignment based on CCF broad region. @@ -155377,7 +158579,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.37 - + Location assignment based on CCF broad region. @@ -155451,7 +158653,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.51 - + Location assignment based on CCF broad region. @@ -155527,7 +158729,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.54 - + Location assignment based on CCF broad region. @@ -155535,7 +158737,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF broad region. @@ -155543,7 +158745,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -155619,7 +158821,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.31 - + Location assignment based on CCF broad region. @@ -155627,7 +158829,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -155635,7 +158837,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.12 - + Location assignment based on CCF broad region. @@ -155710,7 +158912,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.24 - + Location assignment based on CCF broad region. @@ -155718,7 +158920,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.25 - + Location assignment based on CCF broad region. @@ -155793,7 +158995,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.18 - + Location assignment based on CCF broad region. @@ -155801,7 +159003,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.28 - + Location assignment based on CCF broad region. @@ -155876,7 +159078,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.19 - + Location assignment based on CCF broad region. @@ -155884,7 +159086,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.3 - + Location assignment based on CCF broad region. @@ -155959,7 +159161,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.26 - + Location assignment based on CCF broad region. @@ -155967,7 +159169,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.26 - + Location assignment based on CCF broad region. @@ -156043,7 +159245,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -156051,7 +159253,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -156059,7 +159261,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.29 - + Location assignment based on CCF broad region. @@ -156134,7 +159336,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF broad region. @@ -156142,7 +159344,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.37 - + Location assignment based on CCF broad region. @@ -156218,7 +159420,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF broad region. @@ -156226,7 +159428,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.13 - + Location assignment based on CCF broad region. @@ -156234,7 +159436,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.27 - + Location assignment based on CCF broad region. @@ -156310,7 +159512,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -156318,7 +159520,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF broad region. @@ -156326,7 +159528,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.44 - + Location assignment based on CCF broad region. @@ -156401,7 +159603,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -156409,7 +159611,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.41 - + Location assignment based on CCF broad region. @@ -156484,7 +159686,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.11 - + Location assignment based on CCF broad region. @@ -156492,7 +159694,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.41 - + Location assignment based on CCF broad region. @@ -156567,7 +159769,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.15 - + Location assignment based on CCF acronym region. @@ -156575,7 +159777,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.89 - + Location assignment based on CCF broad region. @@ -156650,7 +159852,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.39 - + Location assignment based on CCF acronym region. @@ -156658,7 +159860,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.8 - + Location assignment based on CCF broad region. @@ -156735,7 +159937,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF acronym region. @@ -156743,7 +159945,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.16 - + Location assignment based on CCF acronym region. @@ -156751,7 +159953,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.36 - + Location assignment based on CCF broad region. @@ -156759,7 +159961,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.64 - + Location assignment based on CCF broad region. @@ -156812,7 +160014,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + @@ -156830,14 +160032,14 @@ In addition to their secretory function, fallopian tube secretory epithelial cel https://knowledge.brain-map.org/abcatlas#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%2BDggl%2FA4SgGoeExD3ZBDJOUVRJRTdUQU1QOFBRQUhPNFAABYGvpkqB6awOgaCBR4CS1egGAAcAAAUABgEBAkNCR0MwVTMwVlY5SlBSNjBUSlUAA34AAAAEAAAIVkZPRllQRlFHUktVRFFVWjNGRgAJTFZEQkpBVzhCSTVZU1MxUVVCRwAKAAsBVExPS1dDTDk1UlUwM0Q5UEVURwACNzNHVlREWERFR0UyN00yWEpNVAADAQQBAAIjMDAwMDAwAAPIAQAFAQECIzAwMDAwMAADyAEAAAACAwA%3D https://purl.brain-bican.org/taxonomy/CCN20230722/CS20230722_CLAS_32.h5ad - + - + Inferred to be glutamate secretion, neurotransmission based on expression of Slc17a7 @@ -156845,7 +160047,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.85 - + Location assignment based on CCF broad region. @@ -156919,7 +160121,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.73 - + Location assignment based on CCF broad region. @@ -156993,7 +160195,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.76 - + Location assignment based on CCF broad region. @@ -157067,7 +160269,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.74 - + Location assignment based on CCF broad region. @@ -157151,7 +160353,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.29 - + Location assignment based on CCF broad region. @@ -157159,7 +160361,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.17 - + Location assignment based on CCF broad region. @@ -157235,7 +160437,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -157243,7 +160445,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.13 - + Location assignment based on CCF broad region. @@ -157251,7 +160453,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.34 - + Location assignment based on CCF broad region. @@ -157327,7 +160529,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.14 - + Location assignment based on CCF broad region. @@ -157335,7 +160537,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.16 - + Location assignment based on CCF broad region. @@ -157343,7 +160545,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.26 - + Location assignment based on CCF broad region. @@ -157383,24 +160585,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - GPin-BF Cholinergic GABA (Primate) @@ -157416,7 +160601,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -157424,7 +160609,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -157452,24 +160637,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - LAMP5-CXCL14 GABA (Primate) @@ -157487,7 +160655,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.5 - + Location assignment based on CCF broad region. @@ -157515,24 +160683,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - LAMP5-LHX6 GABA (Primate) @@ -157549,7 +160700,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.5 - + Location assignment based on CCF broad region. @@ -157577,24 +160728,8 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - + - - - - - - BF SKOR1 Glut (Primate) @@ -157610,7 +160745,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -157618,7 +160753,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -157646,24 +160781,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - @@ -157681,7 +160799,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -157689,7 +160807,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.5 - + Location assignment based on CCF broad region. @@ -157728,24 +160846,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - @@ -157762,7 +160863,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -157770,7 +160871,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.8 - + Location assignment based on CCF broad region. @@ -157805,24 +160906,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - GPi Core (Primate) @@ -157839,7 +160923,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -157876,30 +160960,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - - - - - - @@ -157919,7 +160980,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -157927,7 +160988,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -157935,7 +160996,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.6 - + Location assignment based on CCF broad region. @@ -157972,24 +161033,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - GPe-NDB-SI LHX6-LHX8-GBX1 GABA (Primate) @@ -158005,7 +161049,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -158013,7 +161057,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -158041,28 +161085,11 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - OT D1 ICj (Primate) - A Island of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj. + A Islands of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj. D1-ICj (Islands of Calleja) OT D1 ICj OT Granular GABA @@ -158076,13 +161103,13 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. - A Island of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj. + A Islands of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj. https://alleninstitute.github.io/HMBA_BasalGanglia_Consensus_Taxonomy/ https://doi.org/10.1016/j.cub.2021.10.015 @@ -158111,24 +161138,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - + SN-VTR CALB1 Dopa (Primate) @@ -158144,7 +161154,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.7 - + Location assignment based on CCF broad region. @@ -158179,24 +161189,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - SN EBF2 GABA (Primate) @@ -158212,7 +161205,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -158220,7 +161213,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -158248,24 +161241,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - + @@ -158282,7 +161258,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -158290,7 +161266,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.3 - + Location assignment based on CCF broad region. @@ -158325,24 +161301,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - SN GATA3-PAX8 GABA (Primate) @@ -158359,7 +161318,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -158394,24 +161353,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - + SN GATA3-PVALB GABA (Primate) @@ -158428,7 +161370,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.8 - + Location assignment based on CCF broad region. @@ -158463,24 +161405,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - @@ -158497,7 +161422,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.3 - + Location assignment based on CCF broad region. @@ -158505,7 +161430,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -158513,7 +161438,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -158541,24 +161466,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - + SN SOX6 Dopa (Primate) @@ -158574,7 +161482,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -158609,24 +161517,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - SN-VTR-HTH GATA3-TCF7L2 GABA (Primate) A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR-HTH GATA3-TCF7L2 GABA. @@ -158641,7 +161532,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.5 - + Location assignment based on CCF broad region. @@ -158669,24 +161560,8 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - + - - - - - - STH PVALB-PITX2 Glut (Primate) A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the subthalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STH PVALB-PITX2 Glut. @@ -158701,7 +161576,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -158736,24 +161611,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STR FS PTHLH-PVALB GABA (Primate) @@ -158771,7 +161629,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -158806,24 +161664,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STR LYPD6-RSPO2 GABA (Primate) A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR LYPD6-RSPO2 GABA. @@ -158838,7 +161679,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.3 - + Location assignment based on CCF broad region. @@ -158866,24 +161707,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STR SST-ADARB2 GABA (Primate) A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-ADARB2 GABA. @@ -158899,7 +161723,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -158927,24 +161751,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STR SST-CHODL GABA (Primate) @@ -158962,7 +161769,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.8 - + Location assignment based on CCF broad region. @@ -158997,24 +161804,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STR SST-RSPO2 GABA (Primate) A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-RSPO2 GABA. @@ -159029,7 +161819,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.4 - + Location assignment based on CCF broad region. @@ -159057,24 +161847,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STR TAC3-PLPP4 GABA (Primate) @@ -159091,7 +161864,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -159126,24 +161899,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STR-BF TAC3-PLPP4-LHX8 GABA (Primate) A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR-BF TAC3-PLPP4-LHX8 GABA. @@ -159158,7 +161914,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.7 - + Location assignment based on CCF broad region. @@ -159186,24 +161942,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - VIP GABA (Primate) @@ -159221,7 +161960,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.5 - + Location assignment based on CCF broad region. @@ -159256,24 +161995,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STRd Cholinergic GABA (Primate) A dorso-striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd Cholinergic GABA. @@ -159288,7 +162010,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. @@ -159316,24 +162038,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STRd D1 Matrix MSN (Primate) @@ -159350,7 +162055,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. @@ -159385,24 +162090,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STRd D1 Striosome MSN (Primate) @@ -159419,7 +162107,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. @@ -159454,24 +162142,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - + STR D1D2 Hybrid MSN (Primate) @@ -159488,7 +162159,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. @@ -159523,24 +162194,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STRd D2 Matrix MSN (Primate) @@ -159557,7 +162211,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. @@ -159592,24 +162246,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - + STRd D2 StrioMat Hybrid MSN (Primate) A indirect pathway medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 StrioMat Hybrid MSN. @@ -159624,7 +162261,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -159652,24 +162289,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STRd D2 Striosome MSN (Primate) @@ -159686,7 +162306,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 1.0 - + Location assignment based on CCF broad region. @@ -159721,24 +162341,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STR Cholinergic GABA (Primate) A striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR Cholinergic GABA. @@ -159753,7 +162356,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.6 - + Location assignment based on CCF broad region. @@ -159781,24 +162384,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - STRv D1 MSN (Primate) @@ -159815,7 +162401,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.9 - + Location assignment based on CCF broad region. @@ -159850,24 +162436,8 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - + - - - - - - STRv D1 NUDAP MSN (Primate) @@ -159884,7 +162454,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.6 - + Location assignment based on CCF broad region. @@ -159919,24 +162489,8 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - + - - - - - - STRv D2 MSN (Primate) @@ -159953,7 +162507,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.8 - + Location assignment based on CCF broad region. @@ -159988,24 +162542,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - ZI-HTH GABA (Primate) A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:ZI-HTH GABA. @@ -160020,7 +162557,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.5 - + Location assignment based on CCF broad region. @@ -160048,24 +162585,8 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - + - - - - - - @@ -160084,7 +162605,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -160092,7 +162613,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -160100,7 +162621,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.2 - + Location assignment based on CCF broad region. @@ -160128,24 +162649,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - AMY-SLEA-BNST D1 GABA (Primate) A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST D1 GABA. @@ -160160,7 +162664,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.4 - + Location assignment based on CCF broad region. @@ -160188,24 +162692,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - AMY-SLEA-BNST GABA (Primate) A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST GABA. @@ -160220,7 +162707,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.1 - + Location assignment based on CCF broad region. @@ -160248,24 +162735,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - OB Dopa-GABA (Primate) A OB-Dopa-GABA of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB Dopa-GABA. @@ -160280,7 +162750,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.5 - + Location assignment based on CCF broad region. @@ -160308,24 +162778,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - + OB FRMD7 GABA (Primate) A GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB FRMD7 GABA. @@ -160340,7 +162793,7 @@ In addition to their secretory function, fallopian tube secretory epithelial cel 0.6 - + Location assignment based on CCF broad region. @@ -160701,6 +163154,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -160755,12 +163214,6 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - @@ -161091,6 +163544,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -162327,6 +164786,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -162357,6 +164822,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -162471,12 +164942,6 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - @@ -162669,12 +165134,6 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - @@ -162783,12 +165242,6 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - @@ -162987,6 +165440,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -164031,6 +166490,18 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + + + + + + + @@ -164193,15 +166664,15 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - + - + - + - + @@ -164283,6 +166754,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -164541,12 +167018,30 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + + + + + + + + + + + + + @@ -164565,6 +167060,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -164643,6 +167144,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -164727,6 +167234,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -165345,6 +167858,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -167475,6 +169994,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -167547,6 +170072,30 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + + + + + + + + + + + + + + + + + + + @@ -167973,6 +170522,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -168717,12 +171272,6 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - @@ -169245,6 +171794,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -169449,6 +172004,12 @@ In addition to their secretory function, fallopian tube secretory epithelial cel + + + + + + @@ -170582,270 +173143,6 @@ In addition to their secretory function, fallopian tube secretory epithelial cel - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -5054,6 +5065,7 @@ APCs are responsible for stimulating an appropriate immune response. Following a A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -5067,6 +5079,7 @@ APCs are responsible for stimulating an appropriate immune response. Following a + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -6024,6 +6037,7 @@ Tissue-resident macrophages are diverse and heterogenous, likely as a result of + @@ -8275,6 +8289,7 @@ Beyond their role in fighting infections, monocytes play an important role in th + @@ -8460,6 +8475,7 @@ Somatic stem cells respond to environmental signals that regulate their quiescen MESH:D007962 NCIT:C12529 ZFA:0009309 + WBC leucocyte white blood cell immune cell @@ -8489,6 +8505,13 @@ Somatic stem cells respond to environmental signals that regulate their quiescen ZFA:0009309 + + + + WBC + PMID:40794848 + + @@ -13665,6 +13688,7 @@ The balance between cell proliferation and differentiation in embryonic cells is + @@ -13855,7 +13879,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -14237,6 +14260,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. 2014-02-11T17:29:04Z + PBMC CL:2000001 @@ -14249,6 +14273,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. GOC:TermGenie + + + + PBMC + PMID:27696124 + + @@ -14352,6 +14383,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. https://github.com/geneontology/go-ontology/issues/22192 https://github.com/geneontology/go-ontology/issues/25493 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.12 MetaCyc:PEPTIDYLTRANSFERASE-RXN Reactome:R-HSA-156912 @@ -17515,6 +17547,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. + This is the same as GO molecular function molecular function molecular_function GO:0003674 @@ -17698,6 +17731,15 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + @@ -17817,10 +17859,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component @@ -18314,6 +18362,12 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. Wikipedia:Vacuole cellular_component @@ -18359,12 +18413,6 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - - - - - A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. https://github.com/geneontology/go-ontology/issues/14798 Golgi @@ -20473,6 +20521,12 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. https://github.com/geneontology/go-ontology/issues/24968 2012-09-19T15:05:24Z @@ -20711,6 +20765,30 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + + + + + + + + + + + + + + + A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. @@ -20759,6 +20837,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + @@ -20829,6 +20917,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + @@ -20899,6 +20997,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + @@ -20935,6 +21043,70 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. @@ -21997,10 +22169,10 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + https://github.com/geneontology/go-ontology/issues/30193 EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 - Reactome:R-HSA-5333607 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function @@ -22035,12 +22207,6 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 - - - - Reactome:R-HSA-5333607 - GSSeH combines with bGalNAc derivative to form GSSebGalNac - @@ -22062,6 +22228,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 @@ -22112,6 +22279,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function @@ -22859,12 +23027,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 https://github.com/geneontology/go-ontology/issues/26279 cell projection organisation biological_process cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 + cell projection organization @@ -22914,10 +23084,12 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 formation of a cell surface projection biological_process cell projection biogenesis GO:0030031 + cell projection assembly @@ -24585,6 +24757,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + This is not covalently bonded, which conflicts with changes to the parent definition. macromolecular complex macromolecule complex protein containing complex @@ -25688,7 +25861,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - Any biological process involved in the maintenance of an internal steady state. + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + https://github.com/geneontology/go-ontology/issues/31175 homeostasis activation of homeostatic process inhibition of homeostatic process @@ -25705,9 +25879,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - Any biological process involved in the maintenance of an internal steady state. - GOC:jl - ISBN:0395825172 + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + PMID:26265027 @@ -25859,6 +26032,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + @@ -25967,11 +26150,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 cell process cellular process cellular projection cellular_component GO:0042995 + @@ -30666,9 +30851,10 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac https://github.com/geneontology/go-ontology/issues/29474 https://github.com/geneontology/go-ontology/issues/30146 banded collagen fibril + fibrillar collagen cellular_component GO:0098643 - fibrillar collagen + fibrillar collagen complex fibrillar collagen @@ -30733,9 +30919,11 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A supramolecular complex that consists of collagen triple helices associated to form a network. + https://github.com/geneontology/go-ontology/issues/30938 + collagen network cellular_component GO:0098645 - collagen network + complex of network-forming collagens @@ -31197,6 +31385,9 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes. + Overlaps with some cellular components from GO https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 https://github.com/geneontology/go-ontology/issues/28978 @@ -32787,6 +32978,63 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + GC_ID:1 + PMID:27765632 + choanoflagellates + ncbi_taxonomy + Choanoflagellatea + Choanoflagellida + Choanomonada + Choanozoa + choanoflagellates + NCBITaxon:28009 + Choanoflagellata + + + + + choanoflagellates + + + + + + Choanoflagellatea + + + + + + Choanoflagellida + + + + + + Choanomonada + + + + + + Choanozoa + + + + + + choanoflagellates + + + + + @@ -33958,6 +34206,25 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + quality + PATO:0001591 + + curvature + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + WordNet:WordNet + + + + @@ -34341,6 +34608,29 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + + 2010-08-16T03:59:34Z + quality + compressed + PATO:0002254 + + Becoming flat but not necessarily completely flat. + flattened + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + PATOC:CVS + + + + @@ -39175,7 +39465,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -39186,14 +39476,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac membrane organ membrane organ - + - + FMA-def @@ -39962,7 +40252,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -40004,14 +40294,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac gastrula stage gastrula stage - + - + BILS @@ -40496,15 +40786,15 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + - - + + A fluid that is composed of blood plasma and erythrocytes. @@ -40543,34 +40833,34 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac blood blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -42301,7 +42591,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. AAO:0000137 BILA:0000036 @@ -42336,14 +42626,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -42383,7 +42673,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. AAO:0000139 BILA:0000038 @@ -42418,14 +42708,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -42466,7 +42756,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The middle germ layer of the embryo, between the endoderm and ectoderm. AAO:0000304 @@ -42506,14 +42796,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + - + Bgee:AN @@ -42681,7 +42971,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -42746,14 +43036,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb - + - + MA @@ -43167,7 +43457,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -43218,14 +43508,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -43285,7 +43575,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. @@ -43330,7 +43620,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac central nervous system central nervous system - + @@ -43344,7 +43634,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Bgee:AN @@ -43715,7 +44005,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -43740,14 +44030,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -43880,13 +44170,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + - + Skeletal element that is composed of bone tissue. @@ -43928,14 +44218,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac bone element bone element - + - + VSAO-modified @@ -44089,7 +44379,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + A tube extending from the mouth to the anus. @@ -44127,14 +44417,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac digestive tract digestive tract - + - + NCBIBook:NBK10107 @@ -44692,8 +44982,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + @@ -44706,7 +44996,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -44760,34 +45050,34 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -45660,7 +45950,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -45696,14 +45986,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac coelemic cavity lumen coelemic cavity lumen - + - + definitional @@ -45799,8 +46089,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + @@ -45850,11 +46140,11 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -45873,13 +46163,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + ZFA - + EHDAA2 @@ -45920,7 +46210,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. mesodermal cluster @@ -45958,7 +46248,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -45971,7 +46261,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + ZFA @@ -46090,16 +46380,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - - + + + - + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. AAO:0010578 BTO:0001764 @@ -46132,45 +46422,45 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + BTO - + PMID:11523831 - + PMID:11523831 @@ -46389,7 +46679,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -46444,14 +46734,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac bone marrow http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg - + - + FMA MA @@ -46659,8 +46949,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + Anatomical system that is involved in the production of hematopoietic cells. @@ -46701,24 +46991,24 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac hematopoietic system hematopoietic system - + - + - + FMA - + definitional @@ -47102,7 +47392,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -47121,7 +47411,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. AAO:0011086 EFO:0001982 @@ -47144,14 +47434,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac presomitic mesoderm presomitic mesoderm - + - + Bgee:AN @@ -47307,8 +47597,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. AAO:0011072 BTO:0001765 @@ -47337,24 +47627,24 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + Wikipedia - + Bgee:AN @@ -47400,7 +47690,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. AAO:0010568 EFO:0003515 @@ -47426,7 +47716,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -47439,7 +47729,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Bgee:AN @@ -47486,7 +47776,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -47525,7 +47815,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -47538,7 +47828,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + EHDAA2 VHOG @@ -47589,15 +47879,15 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. AAO:0011044 @@ -47614,15 +47904,15 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac heart primordium heart primordium - + - + - + @@ -47635,19 +47925,19 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + ZFA - + ZFA - + XAO @@ -47676,8 +47966,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. AAO:0010571 AEO:0000212 @@ -47701,11 +47991,11 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -47724,13 +48014,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + VHOG:0000680 - + ZFA @@ -47983,7 +48273,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults EHDAA:251 @@ -47998,14 +48288,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac intraembryonic coelom intraembryonic coelom - + - + Wikipedia @@ -48363,8 +48653,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. XAO:0004185 first heart field @@ -48376,24 +48666,24 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac primary heart field primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -48446,7 +48736,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + An epithelial tube that will give rise to the mature heart. AAO:0010411 EFO:0003526 @@ -48465,14 +48755,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac heart tube heart tube - + - + ZFA-modified @@ -49187,7 +49477,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. AAO:0011129 TAO:0001890 @@ -49201,14 +49491,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac skeletal element skeletal element - + - + VSAO @@ -49236,7 +49526,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -49269,14 +49559,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac articular system articular system - + - + FMA @@ -49974,7 +50264,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -49990,14 +50280,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac trunk mesenchyme trunk mesenchyme - + - + EHDAA2 @@ -50115,7 +50405,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. EHDAA2:0001512 EHDAA:424 @@ -50133,14 +50423,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac primitive heart tube primitive heart tube - + - + ZFA @@ -50300,7 +50590,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -50310,7 +50600,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac developing mesenchymal condensation developing mesenchymal condensation - + @@ -50329,7 +50619,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + AEO-modified-relation @@ -50425,7 +50715,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB EHDAA2:0001278 @@ -50439,7 +50729,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac notochordal plate notochordal plate - + @@ -50452,7 +50742,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + EHDAA2 @@ -50481,7 +50771,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -50498,14 +50788,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac notochordal process notochordal process - + - + EHDAA2 @@ -51379,7 +51669,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -51405,7 +51695,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac presumptive paraxial mesoderm presumptive paraxial mesoderm - + @@ -51421,7 +51711,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + https://github.com/obophenotype/uberon/issues/1277 @@ -51498,7 +51788,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -51506,7 +51796,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac dense mesenchyme tissue dense mesenchyme tissue - + @@ -51519,7 +51809,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + AEO @@ -51585,7 +51875,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -51605,14 +51895,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac layer of synovial tissue layer of synovial tissue - + - + BTO @@ -51886,7 +52176,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -51903,14 +52193,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac vascular system vascular system - + - + MA @@ -51940,7 +52230,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -51956,14 +52246,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac entire embryonic mesenchyme entire embryonic mesenchyme - + - + EHDAA2 @@ -52019,7 +52309,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme @@ -52027,14 +52317,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac trunk paraxial mesoderm trunk paraxial mesoderm - + - + EHDAA2 @@ -52129,7 +52419,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -52139,14 +52429,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac anterior lateral plate mesoderm anterior lateral plate mesoderm - + - + ZFA @@ -52286,7 +52576,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -52305,14 +52595,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac UBERON:0010210 blood clot - + - + BTO @@ -52435,7 +52725,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -52445,14 +52735,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac microcirculatory vessel microcirculatory vessel - + - + ZFA @@ -52477,8 +52767,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. FMA:23879 SCTID:129140006 @@ -52490,11 +52780,11 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac subdivision of skeleton subdivision of skeleton - + - + @@ -52507,13 +52797,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + UBERONREF:0000003 - + VSAO @@ -52607,7 +52897,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -52618,7 +52908,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton postcranial axial skeletal system - + @@ -52631,7 +52921,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + cjm @@ -53027,7 +53317,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -53047,7 +53337,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac UBERON:0012429 hematopoietic tissue - + @@ -53060,7 +53350,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + defitional @@ -53733,7 +54023,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -53756,7 +54046,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac entire extraembryonic component entire extraembryonic component - + @@ -53769,7 +54059,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + AEO @@ -54310,14 +54600,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + - + definitional - + @@ -54613,6 +54903,40 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/src/ontology/subsets/blood_and_immune_upper_slim.tsv b/src/ontology/subsets/blood_and_immune_upper_slim.tsv index 9948fe8e3..0f2310d62 100644 --- a/src/ontology/subsets/blood_and_immune_upper_slim.tsv +++ b/src/ontology/subsets/blood_and_immune_upper_slim.tsv @@ -598,9 +598,9 @@ http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0098542 defense response to other organism http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer -http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen +http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers -http://purl.obolibrary.org/obo/GO_0098645 collagen network +http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098657 import into cell http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0098794 postsynapse @@ -658,6 +658,7 @@ http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota +http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda @@ -711,6 +712,7 @@ http://purl.obolibrary.org/obo/PATO_0001407 mononucleate http://purl.obolibrary.org/obo/PATO_0001501 immature http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0001579 contractility +http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0001873 cylindrical @@ -729,6 +731,7 @@ http://purl.obolibrary.org/obo/PATO_0002045 dendritic http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance +http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002318 superelliptic diff --git a/src/ontology/subsets/eye_upper_slim.json b/src/ontology/subsets/eye_upper_slim.json index afa4e853c..bd1f83f03 100644 --- a/src/ontology/subsets/eye_upper_slim.json +++ b/src/ontology/subsets/eye_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2025-12-17" + "val" : "2026-03-17" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2025-12-17/subsets/eye_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2026-03-17/subsets/eye_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -40,7 +40,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { - "val" : "FBbt:00007002" + "val" : "FBbt:00007002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:68646" }, { @@ -56,7 +62,13 @@ }, { "val" : "XAO:0003012" }, { - "val" : "ZFA:0009000" + "val" : "ZFA:0009000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -93,7 +105,13 @@ "val" : "neuronal receptor cell (sensu Animalia)" } ], "xrefs" : [ { - "val" : "ZFA:0009001" + "val" : "ZFA:0009001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -111,7 +129,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009002" + "val" : "ZFA:0009002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -129,7 +153,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007091" + "val" : "ZFA:0007091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -147,14 +177,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009010" + "val" : "ZFA:0009010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Glioblasts are primarily found in the central nervous system and are an integral part of the developing and mature brain tissue. They are primitive progenitor cells with the ability to self-renew and can differentiate into neuroglia, including astrocytes and oligodendrocytes, two primary cells involved in neurotransmission and protection of brain tissue. \nWhen glioblast multiplication is dysregulated, it can lead to harmful manifestations, most notably in the form of an aggressive brain tumor known as Glioblastoma multiforme, one of the most malignant types of neural cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000030" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000030", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "glioblast on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -176,7 +218,13 @@ }, { "val" : "FMA:70563" }, { - "val" : "ZFA:0009011" + "val" : "ZFA:0009011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -192,10 +240,9 @@ "val" : "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, - "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { - "pred" : "hasExactSynonym", + "pred" : "hasNarrowSynonym", "val" : "animal stem cell" } ], "xrefs" : [ { @@ -203,7 +250,13 @@ }, { "val" : "FMA:63368" }, { - "val" : "ZFA:0005957" + "val" : "ZFA:0005957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -213,7 +266,13 @@ "val" : "Stem cells are a unique type of cell that has the remarkable ability to divide and develop into many different types of cells in the body. These cells are undifferentiated, meaning they haven't yet developed into a specific cell type, and they can renew themselves through cell division. As a result, stem cells have the potential to replace damaged or diseased cells in the body, making them a valuable tool in medicine and research.\nThere are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos and can develop into any type of cell in the body. Adult stem cells, on the other hand, are found in various tissues and organs throughout the body and can only develop into certain types of cells.\nStem cells have numerous potential applications in medicine, including the treatment of various diseases and the repair of damaged tissues. For example, they could be used to replace damaged heart tissue after a heart attack or to repair spinal cord injuries. Stem cells also have potential uses in drug development and disease research, as they can be used to model diseases and test potential therapies in vitro.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stem cell" @@ -255,7 +314,13 @@ }, { "val" : "VHOG:0001485" }, { - "val" : "ZFA:0009014" + "val" : "ZFA:0009014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -265,7 +330,13 @@ "val" : "Hematopoietic stem cells (HSCs) are multipotent cells, capable of differentiating into a wide variety of specialized blood cells. During embryonic development hematopoietic stem cells emerge from the hemogenic endothelium, a specialized subset of endothelial cells with hematopoietic potential. HSCs can be found in several organs, in particular in bone marrow, as well as peripheral blood and umbilical cord blood.\nThese stem cells have a distinctive ability to self-renew, and to differentiate into all lymphoid and myeloid cell types that together form the blood and immune systems including erythrocytes (red blood cells), leukocytes (white blood cells), and platelets. Their primary function is to ensure the continuous replenishment of the blood and immune system throughout an individual's lifespan.\nIn response to various signals, hematopoietic stem cells can either remain dormant or actively divide and differentiate. Under normal conditions, the majority of these stem cells exist in a quiescent (inactive) state, making them somewhat resistant to chemotherapy or radiation therapy in the treatment of various diseases such as leukemia. However, when the body encounters stress such as infection, bleeding, or disease, hematopoietic stem cells can rapidly become active in order to replenish the affected cells and maintain homeostasis.\nFurthermore, hematopoietic stem cells are extremely important in the field of regenerative medicine and transplantation. Regarded as lifesaving in the field of oncology, they are often extracted, purified, and reinfused back into the same (autologous transplantation) or different (allogeneic transplantation) individuals to reestablish a healthy, functioning hematopoietic and immune system after high-dose chemotherapy or to replace dysfunctional bone marrow. Understanding and manipulating the behavior of these stem cells has immense potential in treating various blood disorders, autoimmune diseases, and cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "hematopoietic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "hematopoietic stem cell" @@ -305,14 +376,26 @@ "xrefs" : [ { "val" : "BTO:0004911" }, { - "val" : "ZFA:0009015" + "val" : "ZFA:0009015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Erythroid progenitor cells play a key role in the hematopoietic system, specifically in the process of erythropoiesis – the production of red blood cells (erythrocytes). Found within the bone marrow, these cells are dedicated precursors to erythrocytes, and ensue in the hematopoietic lineage from multipotent progenitors. They represent a transitional cell type that bridges the gap between the early-stage erythroid precursors and the maturing red blood cell population.\nThe earliest committed erythroid progenitor cell is thought to be the burst-forming unit-erythroid (BFU-E) cell, which after several cell divisions gives rise to another erythroid progenitor, the colony-forming unit-erythroid (CFU-E) cell. \nErythroid progenitor cells are primarily responsible for responding to the demand for new red blood cells during conditions of physiological stress like infection, blood loss, or illness. This responsive behavior is regulated by a glycoprotein hormone known as erythropoietin, which is produced by the kidneys. Erythropoietin interacts with the receptors on the erythroid progenitor cells, prompting them to proliferate and differentiate into erythroblasts. The erythroblasts then further mature, eventually producing new, functional red cells.\nThe role of erythroid progenitor cells extends beyond their main function of erythrocyte production, as they also participate in maintaining the balance of iron in the body. Upon erythroid differentiation, they increase their uptake of transferrin-bound iron for hemoglobin synthesis, a vital component of red blood cells which allows them to transport oxygen. A deficiency or excess of erythroid progenitor cells can lead to extensive health issues such as anemia or polycythemia respectively, emphasizing their crucial role in human health.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythroid progenitor cell" @@ -344,7 +427,13 @@ "xrefs" : [ { "val" : "FMA:84789" }, { - "val" : "ZFA:0009020" + "val" : "ZFA:0009020", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -400,7 +489,13 @@ "xrefs" : [ { "val" : "BTO:0004730" }, { - "val" : "ZFA:0009021" + "val" : "ZFA:0009021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -410,7 +505,13 @@ "val" : "The common myeloid progenitor (CMP) is a multipotent cell that serves as a crucial intermediary within the overall framework of hematopoietic cell differentiation, which is the process of blood cell production. This part of the hematopoiesis process leads to the formation of myeloid lineage cells, which includes granulocytes (neutrophils, eosinophils, and basophils), monocytes, erythrocytes (red blood cells), and megakaryocytes (platelet-forming cells). \nThe primary function of common myeloid progenitors is differentiation and proliferation into various types of mature blood cells, thereby providing a critical contribution to maintaining homeostasis within the body's immune and circulatory systems. Single-cell analyses have shown that the CMP cell population is heterogeneous with at least two distinct subpopulations, characterized by different cell surface markers and likely already committed to downstream differentiation into either the granulocyte/macrophage lineage or the megakaryocyte/erythrocyte lineage-restricted progenitor. \nThe destiny of a CMP is influenced by numerous cytokines and growth factors in its environment that promote differentiation along specific lineages. For example, IL-3 and GM-CSF stimulate the production of eosinophils, which are essential for the body’s defense against allergens and help fight fungal and parasitic infections. \nBy being able to differentiate into a wide range of different immune cells, common myeloid progenitors play a crucial role in the body's ability to respond to injuries, infections, and other physiological challenges.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "common myeloid progenitor on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "common myeloid progenitor" @@ -450,7 +551,13 @@ "val" : "megakaryocyte/erythroid progenitor cell" } ], "xrefs" : [ { - "val" : "ZFA:0009022" + "val" : "ZFA:0009022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -460,7 +567,13 @@ "val" : "The megakaryocyte-erythroid progenitor (MEP) cell belongs to the multipotent hematopoietic progenitor cells, which can give rise to multiple different cell types. They are found in the bone marrow, the primary organ where new blood cells are generated. MEPs are specially programmed to develop into two distinct blood cell lineages, namely megakaryocytes, which go on to produce platelets for blood clotting, and the erythroid lineage which consists of red blood cells responsible for oxygen transport in the body.\nThe MEP cells are the result of a decision-making process within the hematopoietic stem cell population. Hematopoietic stem cell can differentiate into multiple types of progenitor cells, including myeloid progenitor cells. A further subdivision within this myeloid lineage generates the MEP cells. Therefore, these megakaryocyte-erythroid progenitors represent a key juncture between hematopoietic stem cells and mature blood cell types in the myeloid lineage.\nMegakaryocyte-erythroid progenitor cells play a crucial role in the homeostasis of some of the most crucial constituents of blood. The megakaryocytes produced from these bipotent progenitor cells contribute to hemostasis by producing platelets - small anucleated fragments that are pivotal for blood clotting and preventing bleeding. Similarly, the erythroid lineage from MEP cells gives rise to erythrocytes, which harbor hemoglobin, the molecule that transports oxygen from lungs to every nook and corner of the body. An imbalance or malfunction in MEP function thus can significantly impact human health, leading to diseases like thrombocytopenia or anemia.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte-erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "megakaryocyte-erythroid progenitor cell" @@ -485,7 +598,13 @@ }, { "val" : "MESH:D039901" }, { - "val" : "ZFA:0009024" + "val" : "ZFA:0009024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -507,13 +626,25 @@ }, { "val" : "CALOHA:TS-0650" }, { - "val" : "FBbt:00005083" + "val" : "FBbt:00005083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:70335" }, { "val" : "VHOG:0001529" }, { - "val" : "ZFA:0009025" + "val" : "ZFA:0009025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -542,7 +673,13 @@ }, { "val" : "VHOG:0001482" }, { - "val" : "ZFA:0009026" + "val" : "ZFA:0009026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -573,13 +710,25 @@ }, { "val" : "CARO:0000077" }, { - "val" : "FBbt:00000124" + "val" : "FBbt:00000124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:66768" }, { "val" : "WBbt:0003672" }, { - "val" : "ZFA:0009034" + "val" : "ZFA:0009034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -603,7 +752,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009036" + "val" : "ZFA:0009036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -613,7 +768,13 @@ "val" : "Blood vessel endothelial cells, also known as vascular endothelial cells, form the delicate inner lining of the complex circulatory system, including arteries and veins. These cells form a single, continuous monolayer inside every blood vessel, acting as a crucial biomolecular barrier between the blood, and the rest of the body tissues. They perform various fundamental biological functions, ranging from maintenance of vessel integrity to blood clotting regulation. Additionally, they control the transportation of fluids, molecules, and blood particulate matter from and into the bloodstream.\nOne of the primary functions of blood vessel endothelial cells is to maintain vascular homeostasis - a stable environment within the blood vessels. They accomplish this through several methods: they control vasomotor tone, i.e. the degree of contraction and dilation of blood vessels, by secreting vasoactive substances such as nitric oxide and endothelin; mediate responses to inflammatory stimuli; and they also regulate angiogenesis, the process of new blood vessel formations. Blood vessel endothelial cells play a significant role in preventing blood clot formation by generating a slick, non-thrombogenic surface that disallows platelets or coagulant proteins from adhering to it.\nBlood vessel endothelial cells are sensitive to various stimuli, including shear stress caused by blood flow, and they can respond by altering their morphology, function, and gene expression. This ability to adapt enables blood vessels to remodel and ensure the adequate delivery of nutrients and oxygen to all tissues, regardless of physiological demand variations. Conversely, endothelial dysfunction, often associated with a reduction in the bioavailability of endothelium-derived nitric oxide, can lead to the development of pathological conditions such as atherosclerosis, hypertension, diabetes mellitus, and even aging-related diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "blood vessel endothelial cell" @@ -630,7 +791,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009038" + "val" : "ZFA:0009038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -645,13 +812,25 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "definition" : { + "val" : "An epithelial cell that has a flattened morphology." + }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" }, { - "val" : "ZFA:0009039" + "val" : "ZFA:0009039", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/date", + "val" : "2025-12-16T15:56:39Z" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "squamous epithelial cell" } ] @@ -674,7 +853,13 @@ "xrefs" : [ { "val" : "FMA:66773" }, { - "val" : "ZFA:0009040" + "val" : "ZFA:0009040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -684,7 +869,13 @@ "val" : "Mesothelial cells are crucial components of the mesothelium, a protective layer that lines the body's internal cavities, including pleural cavity (around the lungs), the pericardial cavity (around the heart), and the peritoneal cavity (within the abdomen). Derived from the embryonic mesoderm layer, these cells exhibit a squamous-like epithelial morphology, usually appearing as a single layer of flat, pavement-like cells in their healthy state.\nMesothelial cells play a vital role in various physiological processes, such as intraperitoneal immunity, fibrinolysis, tissue repair, and tumor suppression. Their primary function is to provide a slippery, non-adhesive and protective surface to reduce friction and eases the movements of the organs within the pleural, pericardial, and peritoneal cavities, and they participate in the transport and movement of fluid and various molecules across the so-called serosal cavities. \nThese cells have adaptive capabilities that facilitate their role in many pathological processes. In response to injury or inflammation, mesothelial cells can undergo morphological and functional changes, such as mesothelial-mesenchymal transitions, aiding in wound healing and tissue repair. Dysfunctions of mesothelial cells, however, can lead to serious health conditions, including adhesions, fibrosis, and malignancies such as peritoneal and pleural mesotheliomas.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -702,7 +893,13 @@ }, { "val" : "MESH:D001773" }, { - "val" : "ZFA:0009044" + "val" : "ZFA:0009044", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -737,13 +934,25 @@ "xrefs" : [ { "val" : "BTO:0003811" }, { - "val" : "FBbt:00005125" + "val" : "FBbt:00005125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67313" }, { "val" : "WBbt:0005113" }, { - "val" : "ZFA:0009051" + "val" : "ZFA:0009051", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -766,7 +975,13 @@ "xrefs" : [ { "val" : "BTO:0001037" }, { - "val" : "FBbt:00005124" + "val" : "FBbt:00005124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:84649" }, { @@ -774,7 +989,13 @@ }, { "val" : "WBbt:0005759" }, { - "val" : "ZFA:0009053" + "val" : "ZFA:0009053", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -806,7 +1027,13 @@ }, { "val" : "FMA:66772" }, { - "val" : "ZFA:0009065" + "val" : "ZFA:0009065", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -846,11 +1073,23 @@ }, { "val" : "CALOHA:TS-0415" }, { - "val" : "FBbt:00005144" + "val" : "FBbt:00005144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54536" }, { - "val" : "ZFA:0009073" + "val" : "ZFA:0009073", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -860,7 +1099,13 @@ "val" : "Glial cells, also known as neuroglia or simply glia, are non-neuronal cells in the central and peripheral nervous systems that provide support and protection for neurons. They constitute approximately half of the total cells in the human brain and more than half in other parts of the nervous system. Glial cells perform several key functions including, but not limited to, maintaining homeostasis, forming the myelin sheath around the neuron axons, and providing support and nutrition to neurons.\nThese different functions are performed by various glial cell types, including astrocytes, oligodendrocytes, microglia and other specialized types. Astrocytes, for example, are the most abundant glial cells and provide metabolic and nutrient support to neurons, help regulate the extracellular ion and neurotransmitter levels, and play a role in the formation and maintenance of the blood-brain barrier, contributing to the overall homeostasis and functioning of the nervous system. Additionally, astrocytes are involved in synaptic communication and participate in processes such as synaptogenesis and synaptic pruning.\nOligodendrocytes in the central nervous system function to insulate neurons by producing a fatty substance known as myelin. The myelin sheath enhances the speed and efficiency of nerve impulse conduction along the axons. \nMicroglia, the immune cells of the central nervous system, protect neurons from pathogens and clear away dead neurons through phagocytosis, a process also known as cellular eating. They also contribute to the regulation of inflammation in response to signals of tissue damage or infection in the central nervous system by releasing cytokines and other signaling molecules that modulate the immune response.\nDespite their overarching function in the support and protection of neurons, glial cells have also been shown to play significant roles in the pathophysiology of many psychiatric and neurodegenerative diseases, such as Alzheimer’s, Parkinson’s Disease and multiple sclerosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000125" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "glial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "glial cell" @@ -892,7 +1137,13 @@ }, { "val" : "FMA:54538" }, { - "val" : "ZFA:0009074" + "val" : "ZFA:0009074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -917,7 +1168,13 @@ }, { "val" : "FMA:54537" }, { - "val" : "ZFA:0009075" + "val" : "ZFA:0009075", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -939,7 +1196,13 @@ }, { "val" : "FMA:70614" }, { - "val" : "ZFA:0009079" + "val" : "ZFA:0009079", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -949,7 +1212,13 @@ "val" : "Corneal endothelial cells are specialized cells located on the innermost layer of the cornea, known as the endothelium. The cornea is the clear outer layer of the eye that helps to transmit and focus light into the retina. The endothelium is crucial in maintaining corneal clarity by actively pumping water out of the corneal stroma, the thick, collagen-containing middle layer of the cornea, to prevent swelling and ensure transparency.\nCorneal endothelial cells are characterized by their unique hexagonal shape forming a mosaic, and they are highly metabolically active. Their primary function is to maintain corneal dehydration and thereby clarity through maintaining a barrier and an active 'pump-leak' mechanism, which regulates fluid and solute transport. This transport sustains the deturgescence (state of being non-swollen) of the corneal stroma, since stromal swelling can cause corneal opacification, hindering light transmission. Importantly, human corneal endothelial cells have limited regenerative capacity, so damage to them, through disease, aging, or surgical trauma may result in vision loss.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000132" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000132", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "corneal endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -967,7 +1236,13 @@ "val" : "neurectoderm cell" } ], "xrefs" : [ { - "val" : "ZFA:0009080" + "val" : "ZFA:0009080", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1039,14 +1314,26 @@ }, { "val" : "FMA:70546" }, { - "val" : "ZFA:0009081" + "val" : "ZFA:0009081", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. These cells originate mainly from the mesoderm of the embryo, which forms connective tissues, muscle, and the circulatory and urinary systems. However, in adults, MSCs are found in multiple tissues, including bone marrow, adipose tissue, the umbilical cord, and dental tissues. \nThe primary function of MSCs is to maintain and repair the tissues in which they are found. When damage occurs, the MSCs are able to migrate to the site of injury, where they aid in regenerating the damaged tissue by differentiating into the required cell type and by secreting growth factors that enhance tissue repair and reduce inflammation. Furthermore, MSCs can also act as immunomodulators, suppressing immune reactions and reducing inflammation, both locally and systemically.\nApart from their role in tissue maintenance and repair, MSCs are integral to the field of regenerative medicine and are being investigated for their therapeutic potential in various clinical settings. Owing to their multipotent nature, immunomodulatory activity, and the relative ease of isolation, these cells can be engineered and translated into therapies to treat a variety of diseases, including bone and cartilage defects, liver diseases, heart disorders, and autoimmune diseases, amongst others. They have also been used as vectors for anticancer agents and in cell and gene therapy applications.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val" : "https://github.com/obophenotype/cell-ontology/issues/474" @@ -1075,7 +1362,13 @@ "xrefs" : [ { "val" : "VHOG:0001678" }, { - "val" : "ZFA:0009090" + "val" : "ZFA:0009090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1107,7 +1400,13 @@ }, { "val" : "VHOG:0001679" }, { - "val" : "ZFA:0009091" + "val" : "ZFA:0009091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1117,7 +1416,13 @@ "val" : "Melanocytes are specialized cells prevalently found in the skin, but also present in the hair follicles, eyes, inner ear, bones, heart, and brain. Their primary function is the synthesis of melanin, a pigment responsible for coloration of skin, hair, and eyes. The presence and distribution of this pigment play a crucial role in the body's defense mechanism against harmful ultraviolet radiation.\nIn addition to melanin production, melanocytes also engage in a variety of other biological functions. They play a fundamental role in the immune response, owing to their ability to present antigens to T cells. Furthermore, they contribute to the maintenance of the skin's homeostasis by regulating processes such as extracellular matrix remodeling and cytokine production. A balance in melanocyte function is pivotal, as dysfunctions often result in dermatological disorders. For instance, the loss of melanocytes or reduction in their function may lead to hypopigmentation conditions such as vitiligo, whereas an abnormal increase could result in hyperpigmentation disorders or melanoma, a dangerous type of skin cancer.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000148" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000148", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "melanocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1186,7 +1491,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1201,15 +1506,30 @@ }, { "val" : "CALOHA:TS-2032" }, { - "val" : "FBbt:00005074" + "val" : "FBbt:00005074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67328" }, { "val" : "WBbt:0003675" }, { - "val" : "ZFA:0009114" + "val" : "ZFA:0009114", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle cell" }, { @@ -1249,7 +1569,13 @@ }, { "val" : "FMA:14072" }, { - "val" : "ZFA:0009118" + "val" : "ZFA:0009118", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1259,7 +1585,13 @@ "val" : "Smooth muscle cells are a specialized type of muscle cells that are primarily found within the walls of hollow organs such as the intestine, stomach, bladder, uterus, and blood vessels. These cells are an essential component of the autonomic nervous system controling involuntary movements within the body.\nSmooth muscle cells play a vital role in many physiological processes due to their unique functionality. They can contract and relax in a slow, sustained, and controlled manner to help modulate the size and shape of the lumens of the organs they surround. For example, in the digestive system, coordinated contraction and relaxation of smooth muscle cells propels food along the gastrointestinal tract - a process known as peristalsis. In the blood vessels, the smooth muscle cells, by contracting or relaxing, either constrict or dilate the vessels, which in turn, help regulate blood flow and pressure.\nOn a cellular level, smooth muscle cells possess a single, centrally located nucleus and contain an arranged network of actin and myosin filaments, which are the proteins responsible for muscle contraction. Unlike their counterparts in skeletal or cardiac muscles, these cells lack specific contact points for these filaments, hence the lack of visible striations. Furthermore, the contraction of smooth muscle cells is regulated by hormones and neurotransmitters, such as acetylcholine and norepinephrine, adding an additional layer of complex regulation to these highly specialized cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000192" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000192", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "smooth muscle cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "smooth muscle cell" @@ -1301,18 +1633,36 @@ }, { "val" : "CALOHA:TS-0868" }, { - "val" : "FBbt:00004211" + "val" : "FBbt:00004211", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86740" }, { - "val" : "ZFA:0009127" + "val" : "ZFA:0009127", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Photoreceptor cells are specialized types of neurons found in the retina, responsible for the vital task of converting light into signals that can stimulate a visual response. These cells are called photoreceptor cells because they are light-sensitive, enabling vision in conditions ranging from extremely dim to very bright light. There are two main types of photoreceptor cells in the human eye: rods, which are highly sensitive to light and allow for vision in low-light conditions, and cones, which are responsible for color vision and function best in bright light.\nThe photoreceptor cells function by absorbing light rays and converting them into electrical signals. These signals are then sent to the brain via the optic nerve and are interpreted as visual images. This process begins when the photopigment (a light-sensitive compound) found in photoreceptor cells absorbs light, which triggers a chemical reaction. This reaction leads to changes in the photopigment's configuration and, consequently, alters its electrical properties. This change initiates a signal that is transmitted through the cell and onwards to connecting neurons.\nFurthermore, photoreceptor cells exhibit a unique and highly specialized structure that reflects their function. Rods, named because of their elongated, rod-shaped structure, consist of an outer segment filled with disks containing rhodopsin, the photopigment responsible for detecting light. Cones, on the other hand, are more conical and have three different types of photopigments, each one sensitive to a different range of wavelengths, allowing for the perception of color. Given the importance of photoreceptor cells in vision, damage or degeneration to these cells can lead to vision impairment or blindness, highlighting their key role in visual perception.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000210" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000210", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "photoreceptor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "photoreceptor cell" @@ -1332,7 +1682,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009128" + "val" : "ZFA:0009128", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1355,7 +1711,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-0995" }, { - "val" : "ZFA:0009131" + "val" : "ZFA:0009131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1369,7 +1731,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009136" + "val" : "ZFA:0009136", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1393,7 +1761,13 @@ "xrefs" : [ { "val" : "FMA:72549" }, { - "val" : "ZFA:0009137" + "val" : "ZFA:0009137", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1420,14 +1794,26 @@ "xrefs" : [ { "val" : "FMA:72554" }, { - "val" : "ZFA:0009138" + "val" : "ZFA:0009138", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesodermal cells are pluripotent and the most abundant in the human body. They contribute to the development of several structures such as the skeletal muscles, bones, heart and blood vessels, kidneys, gonads, connective tissues, and certain layers of the skin. Hence, the mesoderm is often regarded as an active and diverse layer due to its role in forming many bodily structures. \nIn embryonic development, these cells are instrumental, contributing to the body's structures through a carefully coordinated sequence of morphogenetic movements. This process forms the complex multicellular architecture of tissues and organs from a simple ball of cells. Without the function of mesodermal cells, the body's integral structures and systems would cease to form correctly, leading to developmental disorders such as axial mesodermal dysplasia complex\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesodermal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesodermal cell" @@ -1450,7 +1836,13 @@ "xrefs" : [ { "val" : "FMA:72555" }, { - "val" : "ZFA:0009139" + "val" : "ZFA:0009139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1489,7 +1881,13 @@ "val" : "Erythrocytes, also known as red blood cells, are a type of specialized cell that make up the largest percentage of cells in the human body. Erythrocytes are biconcave in shape and lack nuclei and organelles, allowing them to carry oxygen and carbon dioxide through the bloodstream more efficiently. The main function of erythrocytes is to transport oxygen from the lungs to the body's tissues and organs, and to transport carbon dioxide from the body's tissues to the lungs, where it can be exhaled out of the body. Hemoglobin, a protein located inside erythrocytes, is responsible for binding to oxygen. \nErythrocytes are produced in the bone marrow and have a lifespan of approximately 120 days before they are broken down and recycled by the body. Erythrocytes are regulated by the hormone erythropoietin, which is produced by the kidneys and liver in response to low oxygen levels in the body, thereby stimulating erythrocyte production .\nIn addition to their role in oxygen transport, erythrocytes also play a key role in regulating the body's pH levels. Without erythrocytes, oxygen would not be able to be transported efficiently throughout the body and tissues would not receive the necessary oxygen to function properly. Overall, erythrocytes are essential for maintaining the health and homeostasis of the body.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythrocyte on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythrocyte" @@ -1524,7 +1922,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009154" + "val" : "ZFA:0009154", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1534,7 +1938,13 @@ "val" : "Eye photoreceptor cells, also commonly known as photoreceptors, are specialized types of cells found in the retina, the light-sensitive layer at the back of the eye. They are integral to the complex process of vision, as they are directly involved in converting light into electrical signals. This process is known as phototransduction. There are two primary classes of photoreceptor cells; rods, which function mainly in dim light and provide black-and-white vision, and cones, which function in brighter light and allow for the perception of color.\nRods and cones carry out their roles through sophisticated biochemical reactions. The main component of these reactions is a protein called opsin, which binds to a small molecule known as retinal. In the presence of light, retinal changes its shape, leading to a series of chemical reactions that result in changes to the cell’s electrical potential, thus creating an electrical signal that travels to the optic nerve. Rod cells possess only one kind of opsin, called rhodopsin, which only allows them to distinguish between light and dark. Conversely, cone cells have three types of opsins, allowing for the differentiation of various colors.\nThe spatial distribution of these cell types throughout the retina also contributes to their function. Rod cells are more numerous and are distributed more at the periphery of the retina, contributing to peripheral and night vision. On the other hand, cone cells are concentrated in the macula, a tiny central region in the retina, and with the highest density in the fovea, a small pit in the macula. This distribution of cones lies at the base of fine detail and color vision in the central visual field. In summary, eye photoreceptor cells carry out the primary function of transforming light into visual signals, a role that is crucial for the overall process of vision.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000287" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000287", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "eye photoreceptor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "eye photoreceptor cell" @@ -1597,7 +2007,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009164" + "val" : "ZFA:0009164", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1617,7 +2033,13 @@ "xrefs" : [ { "val" : "FMA:86667" }, { - "val" : "ZFA:0007086" + "val" : "ZFA:0007086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1635,7 +2057,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009166" + "val" : "ZFA:0009166", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1659,7 +2087,13 @@ "xrefs" : [ { "val" : "FMA:70564" }, { - "val" : "ZFA:0009169" + "val" : "ZFA:0009169", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1673,7 +2107,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009170" + "val" : "ZFA:0009170", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1687,7 +2127,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009174" + "val" : "ZFA:0009174", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1705,7 +2151,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009175" + "val" : "ZFA:0009175", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1760,7 +2212,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009190" + "val" : "ZFA:0009190", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1778,7 +2236,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009193" + "val" : "ZFA:0009193", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1800,7 +2264,13 @@ }, { "val" : "FMA:83624" }, { - "val" : "ZFA:0009226" + "val" : "ZFA:0009226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1810,7 +2280,13 @@ "val" : "Stromal cells constitute a significant portion of the structural cellular milieu (stroma) that supports the function of parenchymal (functional) cells within an organ. The stroma is the connective, supportive framework of biological tissues with various functions depending on the specific organ and cell type. Stromal cells, derived from the mesenchymal lineage, play crucial roles in creating, maintaining, and repairing the tissue microenvironment in virtually all mammalian organs, making these cells indispensable to biological function.\nAdditionally, stromal cells secrete growth factors, cytokines, and extracellular matrix (ECM) molecules to constitute an interactive cellular network and ensure an optimal environment for the functional cells. Beyond mere structural support, these cells are instrumental in wound healing, inflammation, and maintaining tissue integrity. They may also influence the behavior of other cell types through direct cell-cell interactions or paracrine signaling.\nClinically and in research, stromal cells often draw attention due to their interaction with tumors in the cancer microenvironment. Over the past years, the role of stromal cells as facilitators of tumor growth and metastasis has been recognized increasingly. They contribute to cancer progression not only by modulating the ECM but also through the secretion of various bioactive molecules and interacting with immune cells, thereby influencing the immunologic responses to tumors.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stromal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stromal cell" @@ -1837,14 +2313,26 @@ "xrefs" : [ { "val" : "FMA:84798" }, { - "val" : "ZFA:0009235" + "val" : "ZFA:0009235", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "A precursor to the smooth muscle cell, the smooth muscle myoblast, is integral to various body systems, including the cardiovascular, gastrointestinal, and respiratory systems. Smooth muscle myoblasts arise from the differentiation of mesenchymal stem cells, a process tightly regulated by specific genetic factors and environmental signals. Their role extends to myogenesis, particularly in the formation of muscular tissue, especially during embryonic development.\nSmooth muscle myoblasts possess distinctive cellular characteristics. In contrast to skeletal muscle myoblasts, they do not fuse to create multinucleated fibers. Instead, they differentiate into individual, uninucleated smooth muscle cells. This differentiation unfolds in two distinct phases: proliferation, marked by rapid division to increase cell numbers, and differentiation, involving structural and functional transformation into mature smooth muscle cells. This intricate process is intricately mediated by various signaling molecules and transcription factors.\nFunctionally, smooth muscle myoblasts and the mature muscle cells they generate play pivotal roles in various physiological processes. Smooth muscle cells orchestrate involuntary muscle responses and are integral to body systems that regulate blood flow, propel food along the digestive tract, and control airflow in the respiratory tract. These diverse functions underscore the significance of smooth muscle myoblasts in the body's growth, maintenance, and overall function.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000514" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000514", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "smooth muscle myoblast on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "smooth muscle myoblast" @@ -1867,7 +2355,13 @@ "xrefs" : [ { "val" : "FMA:87653" }, { - "val" : "ZFA:0009238" + "val" : "ZFA:0009238", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1884,7 +2378,13 @@ "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009241" + "val" : "ZFA:0009241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1907,7 +2407,13 @@ }, { "val" : "CALOHA:TS-0683" }, { - "val" : "FBbt:00005106" + "val" : "FBbt:00005106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54527" }, { @@ -1915,7 +2421,13 @@ }, { "val" : "WBbt:0003679" }, { - "val" : "ZFA:0009248" + "val" : "ZFA:0009248", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1944,7 +2456,13 @@ }, { "val" : "FMA:83377" }, { - "val" : "ZFA:0009249" + "val" : "ZFA:0009249", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -2003,7 +2521,13 @@ "xrefs" : [ { "val" : "FMA:83505" }, { - "val" : "ZFA:0005236" + "val" : "ZFA:0005236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2048,7 +2572,13 @@ "xrefs" : [ { "val" : "FMA:83506" }, { - "val" : "ZFA:0005241" + "val" : "ZFA:0005241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2189,7 +2719,13 @@ "val" : "A megakaryocyte is a large, unique, and complex cell type found primarily in the bone marrow, the spongy, semi-solid tissue located in the medullary cavities of certain bones. The term ‘megakaryocyte’ is derived from the Greek 'mega', meaning great, and 'karyon', referring to the nucleus. Megakaryocytes are characterized by their large size, typically with a diameter of 50-100 µm in humans, and the presence of a multilobulated nucleus; they are the largest hematopoietic cells in the bone marrow but also the rarest cells. \nThe primary function of a megakaryocyte is the production of platelets, also known as thrombocytes. Platelets are small, anucleate cell fragments that play a crucial role in the process of hemostasis, the arrest of blood loss from a damaged blood vessel. The process begins when the megakaryocyte extends long, branching processes called proplatelets, into the sinusoidal blood vessels present in the bone marrow. These proplatelets then fragment into the discoid structures recognized as platelets. Each megakaryocyte can produce thousands of platelets during its lifespan. \nApart from platelet production, megakaryocytes are involved in several other functions. They express immune-sensing receptors such as Fc-γ receptor and Toll-like receptors and produce factors such as platelet factor 4 and platelet-derived growth factor that can stimulate the immune system. Also, in certain pathological conditions, megakaryocytes release TGF-β and PDGF and contribute to bone marrow fibrosis, a condition characterized by excessive accumulation of fibrous tissue in the bone marrow leading to anemia. Recent studies have also highlighted the role of megakaryocytes in regulating hematopoiesis, the process of blood cell production. They can influence the bone marrow microenvironment and control the behavior of hematopoietic stem cells, the progenitors of all types of blood cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2209,7 +2745,13 @@ }, { "val" : "MESH:D012156" }, { - "val" : "ZFA:0009252" + "val" : "ZFA:0009252", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2245,7 +2787,13 @@ }, { "val" : "FMA:67766" }, { - "val" : "ZFA:0009255" + "val" : "ZFA:0009255", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2271,7 +2819,13 @@ "val" : "chondroplast" } ], "xrefs" : [ { - "val" : "ZFA:0009258" + "val" : "ZFA:0009258", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2300,7 +2854,13 @@ }, { "val" : "FMA:67748" }, { - "val" : "ZFA:0009262" + "val" : "ZFA:0009262", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2310,7 +2870,13 @@ "val" : "Retinal cone cells, or simply cone cells, are one out of the two types of photoreceptor cells in the retina, the other being retinal rod cells. They function by converting light into signals that can lead to a visual perception. These cells are less sensitive to light compared to rod cells, but they play a crucial role in our vision system for their ability to perceive color and provide sharp visual acuity. They are responsible for our daylight and color vision, enabling an individual to perceive fine detail and rapid changes in light levels.\nCone cells are specialized and named based on the absorption spectra of the visual pigments they contain, giving rise to three types of cone cells: short-wavelength S-cones (blue cones), middle-wavelength M-cones (green cones), and long-wavelength L-cones (red cones). The distribution of these cones across the retina differs, with greater densities at the central fovea region, contributing to why our central vision is so sharp and color-detailed compared to peripheral vision.\nThe outer segments of retinal cone cells house the photopigments that absorb light and initiate the process of phototransduction, a biochemical event by which the light signal is transformed into an electrical signal. When a cone cell is stimulated by light, an electrochemical reaction triggers nerve impulses, which are then transmitted to the brain by the optic nerve. There, these impulses are processed into the images that we see. Each type of cone responds to different wavelengths of light, enabling us to perceive a spectrum of color. By working in conjunction with rod cells, which are adapted for low-light vision scenarios, the cone cells provide us with a comprehensive and adaptable vision system.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000573" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000573", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal cone cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "retinal cone cell" @@ -2338,7 +2904,13 @@ }, { "val" : "FMA:70551" }, { - "val" : "ZFA:0009264" + "val" : "ZFA:0009264", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2348,7 +2920,13 @@ "val" : "Corneal epithelial cells are a specialized cell type that form the outermost layer of the cornea, the transparent dome-shaped tissue that covers the front of the eye. The corneal epithelium is 5-7 cells thick and is comprised of inner basal cells, middle wing cells and superficial squamous cells. \nThe corneal epithelium plays a crucial role in the maintenance of corneal transparency, protection against external insults, and the refractive power of the cornea. This cell type is responsible for the formation of tight junctions, desmosomes, and hemidesmosomes, which provide structural support to the corneal epithelium and prevent the infiltration of foreign particles and microorganisms. \nCorneal epithelial cells also have a unique and highly organized cytoskeleton that confers mechanical integrity and limits the penetration of foreign substances. Additionally, corneal epithelial cells secrete a variety of proteins and lipids that help to maintain the hydration and clarity of the cornea. These include mucins, which form a lubricating layer that facilitates blinking and limits dryness, and crystallins, which appear to protect against UV- and oxidative stress-induced apoptosis.\nDysfunction of corneal epithelial cells due to infections, inflammation, or injury can lead to corneal opacity, scarring, and impaired vision.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000575" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "corneal epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2373,7 +2951,13 @@ }, { "val" : "FMA:67747" }, { - "val" : "ZFA:0009275" + "val" : "ZFA:0009275", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2383,7 +2967,13 @@ "val" : "Retinal rod cells, often referred to simply as \"rod cells”, are a specialized type of photoreceptor cells found in the retina. Their primary function is to detect and convert light into electrochemical signals, which are then transmitted to the brain via nerve impulses. Compared to other types of photoreceptor cells, namely retinal cone cells, rod cells are more sensitive to light, and thus play a crucial role in night and peripheral vision.\nRod cells are named for their long, cylindrical shape, which is distinct from the cone-like shape of retinal cone cells. The structure of a rod cell is complex, with different sections responsible for various aspects of its function. The outer segment contains densely packed, light-sensitive membrane discs filled with a pigment called rhodopsin. When light hits rhodopsin, it prompts a chemical reaction that leads to the generation of electrochemical signals. These signals are processed in the cell's inner segment, which contains the cell's primary organelles, including the nucleus and mitochondria, and transmitted through the cell's synaptic terminal to the secondary neurons in the retina.\nRod cells are distributed across the majority of the retina, with the highest density found in the peripheral edges. This distribution, coupled with their high sensitivity to light, explains why rod cells contribute significantly to peripheral and low-light vision. However, they do not pick up color and have low spatial acuity, which means that while rod cells can detect the presence of light and movement, the finer details and colors of an image are processed mainly by cone cells. Together, rod cells and cone cells work in concert to enable a wide range of visual capabilities, making vision a complex and intricate biological process.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000604" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000604", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal rod cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "retinal rod cell" @@ -2414,7 +3004,13 @@ "xrefs" : [ { "val" : "BTO:0003064" }, { - "val" : "ZFA:0009280" + "val" : "ZFA:0009280", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2424,7 +3020,13 @@ "val" : "Mueller cells, also referred to as Műller glial cells, are a type of radial glial cell found specifically within the retina, the light-sensitive tissue lining the back interior surface of the eye. They derive their name from Heinrich Müller, who first described these cells in the mid-nineteenth century. These support cells contribute to maintaining the homeostasis and structural integrity of the retina. Mueller cells span the entire thickness of the retina, thus representing the only cell type that traverses all layers.\nMueller cells play a crucial role in maintaining the metabolic environment of retinal neurons and participating in the visual signal transduction. They have a unique organization and possess a wide range of processes, giving them direct contact with virtually every type of cell in the retina—including photoreceptors, bipolar cells, and ganglion cells. These cells actively uptake and recycle neurotransmitters, modulate chemical levels within the extracellular space, and are involved in potassium siphoning, thus supporting neuronal signaling. Due to these functions, they play a vital role in maintaining the physiological and functional stability of the retina.\nMoreover, Mueller cells are also responsible for maintaining the structural integrity of the retina. They serve as the retinal framework by providing structural support to neurons and blood vessels. They contribute to the formation and maintenance of the inner limiting membrane, comprising their end-feet at the vitreous surface. Additionally, they play an essential role during injury or disease, exhibiting reactive gliosis – a process where these cells undergo morphological and functional changes to aid in repair and protection from further damage. While their protective role is important, it's also worth noting that overactivation of Mueller cells may result in retinal scarring or degeneration, reinforcing their complex and delicate role in retinal health and disease.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000636" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000636", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Mueller cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2437,11 +3039,23 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "FBbt:00100291" + "val" : "FBbt:00100291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "WBbt:0006829" }, { - "val" : "ZFA:0009290" + "val" : "ZFA:0009290", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2462,14 +3076,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009291" + "val" : "ZFA:0009291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Muscle precursor cells, commonly referred to as myogenic progenitor cells or myoblasts, play a pivotal role in the intricate processes of muscle regeneration and development. As undifferentiated cells, they harbor the potential to evolve into distinct specialized cells, specifically the muscle cell or myocyte. Their crucial contribution lies in guiding the transformation of the mesodermal layer, one of the three primary germ cell layers in the early embryo, into fully developed skeletal muscle tissues during embryonic development.\nMuscle precursor cells are characterized by their proliferative capacity and rapid differentiation into mature myocytes. They fuse into myotubes, culminating in the formation of muscle fibers. Their responsiveness to signals such as insulin-like growth factors, transforming growth factor-β, and neural inputs enables precise control over their proliferation and differentiation. This regenerative capacity equips them with the ability to repair injured or damaged muscle tissue, a critical function in preserving muscle homeostasis and overall function. These cells also actively contribute to adaptive responses, such as muscle growth and strengthening, in reaction to factors like training or aging.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "muscle precursor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle precursor cell" @@ -2491,7 +3117,13 @@ "val" : "forebrain radial glial cell" } ], "xrefs" : [ { - "val" : "ZFA:0009292" + "val" : "ZFA:0009292", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2538,14 +3170,26 @@ }, { "val" : "MESH:D053687" }, { - "val" : "ZFA:0009307" + "val" : "ZFA:0009307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Somatic stem cells, also known as adult stem cells, are undifferentiated cells found throughout the body post-embryonic development. They reside in specialized niches within tissues such as the bone marrow, brain, muscles, skin, and liver. Fundamentally, these cells possess the ability to self-renew, maintaining their numbers, and to generate differentiated cells that replace dying cells and repair damaged tissues. \nThe potency of somatic stem cells varies based on their tissue of origin. For instance, hematopoietic stem cells in the bone marrow exhibit multipotency, giving rise to all blood cell types. Conversely, muscle stem cells display unipotency, generating only muscle cells.\nSomatic stem cells respond to environmental signals that regulate their quiescence, activation, and differentiation states. In response to tissue injury, they proliferate and differentiate into specific mature cell types to replace lost or damaged cells. Intricate mechanisms ensure a delicate balance between self-renewal and differentiation, guiding tissue maintenance and repair without risking aberrant cell proliferation leading to tumor formation.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "somatic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somatic stem cell" @@ -2585,7 +3229,13 @@ }, { "val" : "MESH:D012165" }, { - "val" : "ZFA:0009310" + "val" : "ZFA:0009310", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2595,7 +3245,13 @@ "val" : "Retinal ganglion cells (RGCs) are a type of neuron located near the inner surface of the retina, playing a critical role in the visual pathway. There are approximately 1 million RGCs in a typical human eye, each receiving inputs from multiple photoreceptor cells. As the only neurons in the retina that send information to the brain, they are the final output neurons of the vertebrate retina, and their axons constitute the majority of fibers in the optic nerve. \nThe primary function of RGCs is to receive visual information from photoreceptors via intermediary bipolar and amacrine cells, process it, and transmit it to the brain through their axons. The information that RGCs relay encompasses various aspects of the visual field, including color, contrast, brightness, and motion. A diverse population of RGCs, up to 30 distinct subtypes, each contributes to a specific aspect of vision, such as object motion, edge detection, or color contrast, illustrating the complexity of visual data processing that occurs already at the retinal level.\nRGCs also play a role in the regulation of circadian rhythms and the pupillary light reflex. Some RGCs contain the photopigment melanopsin and respond directly to light, separately from the retinal rod and cone cells found in the outer retina. These photosensitive RGCs are primarily involved in subconscious vision, particularly the regulation of circadian rhythms and the pupillary light reflex in response to changes in ambient light intensity. Hence, RGCs serve a highly specialized and diverse role in transmitting visual information and regulating light-dependent responses, view modalities, and key physiological processes.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000740" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000740", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal ganglion cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "retinal ganglion cell" @@ -2628,7 +3284,13 @@ "xrefs" : [ { "val" : "BTO:0004120" }, { - "val" : "ZFA:0009315" + "val" : "ZFA:0009315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2638,7 +3300,13 @@ "val" : "Retina horizontal cells are a specialized type of neuron found in the inner nuclear layer of the retina. They play a crucial role in the visual system by integrating and regulating the input from multiple photoreceptor cells, which sense and respond to light. Retina horizontal cells are so named due to their characteristic flat horizontal orientation, with their dendrites and axons coursing laterally in a plane parallel to the retinal surface.\nRetina horizontal cells are synaptically connected with photoreceptor cells (i.e., cones and rods) and bipolar cells. Their primary function is to facilitate the process of lateral inhibition, where an excited neuron reduces the activity of its neighbors. This capability is central to the phenomenon of \"contrast enhancement\" in visual perception, where the borders between light and dark areas are accentuated to better resolve images. Retina horizontal cells receive inputs from these neighboring photoreceptor cells and transmit their inhibitory output to not only photoreceptor cells but also bipolar cells, fine-tuning the responsiveness to changes in light intensity and differences in wavelengths.\nMoreover, retina horizontal cells play a substantial role in adaptation of retinal response to different light levels. In bright light conditions, they aid the reduction of the overall response to light stimuli, thus aiding in the prevention of photoreceptor saturation. These neurons are adept at adjusting the gain and thus the dynamic range of photoreceptors supporting the vision process under variable lighting conditions - from dim moonlight to bright sunshine. Therefore, retina horizontal cells contribute considerably to the adaptability, sharpness, and detail perception of our visual system.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000745" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000745", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retina horizontal cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2668,7 +3336,13 @@ "xrefs" : [ "geo:GSE137537" ] } ], "xrefs" : [ { - "val" : "ZFA:0009318" + "val" : "ZFA:0009318", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2678,7 +3352,22 @@ "val" : "The retinal bipolar neuron is an integral part of the eye, specifically located within the retina. They are secondary neurons in the visual pathway and primarily serve to transmit information from photoreceptor cells, which respond to light, to retinal ganglion cells, which carry the signal to the brain. As such, these cells play a pivotal role in our ability to interpret and perceive visual information.\nThe structure of retinal bipolar neurons is unique and significant to their function. They are termed \"bipolar\" due to their morphology, having two poles: a single dendrite on one end and an axon on the other. The dendrite end connects to photoreceptor cells (rods or cones), while the axon end synapses with retinal ganglion cells. In the center of the dendrite and axon lies the cell body, which houses the cell's nucleus and other vital organelles.\nAt the functional level, retinal bipolar neurons can be categorized into ON and OFF types based on their response to light. 'ON' bipolar cells are depolarized (electrical potential across the cell membrane decreases) under light conditions, thereby increasing their rate of neurotransmitter release onto the downstream ganglion cells. In contrast, 'OFF' bipolar cells are hyperpolarized (electrical potential increases) in light conditions, decreasing their rate of neurotransmitter release. This dual system allows for a fine-tuned response and the ability to perceive differences in light intensity and contrast, thus creating a nuanced and detailed visual world.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000748" + "val" : "https://celltype.info/project/544/dataset/1157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "reference transcriptomic data on Cell Annotation Platform" + } ] + } + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000748", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal bipolar neuron on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2698,7 +3387,13 @@ }, { "val" : "MESH:D022423" }, { - "val" : "ZFA:0009324" + "val" : "ZFA:0009324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2727,7 +3422,13 @@ }, { "val" : "FMA:83516" }, { - "val" : "ZFA:0009325" + "val" : "ZFA:0009325", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2760,7 +3461,13 @@ }, { "val" : "MESH:D004900" }, { - "val" : "ZFA:0005237" + "val" : "ZFA:0005237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2790,7 +3497,13 @@ }, { "val" : "CALOHA:TS-0448" }, { - "val" : "ZFA:0009354" + "val" : "ZFA:0009354", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2822,7 +3535,13 @@ }, { "val" : "FMA:70339" }, { - "val" : "ZFA:0009356" + "val" : "ZFA:0009356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2861,7 +3580,13 @@ }, { "val" : "FMA:83598" }, { - "val" : "ZFA:0005830" + "val" : "ZFA:0005830", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2924,7 +3649,13 @@ "xrefs" : [ { "val" : "FMA:69074" }, { - "val" : "ZFA:0009385" + "val" : "ZFA:0009385", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2954,7 +3685,13 @@ "xrefs" : [ { "val" : "FMA:69076" }, { - "val" : "ZFA:0009388" + "val" : "ZFA:0009388", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3000,7 +3737,13 @@ "val" : "2010-08-24T02:06:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "endothelial cell of vascular tree on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "endothelial cell of vascular tree" @@ -3105,7 +3848,13 @@ "val" : "2010-09-13T04:09:27Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002303" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002303", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "pigmented ciliary epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3145,7 +3894,13 @@ "val" : "2010-09-13T04:09:31Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002304" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002304", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "non-pigmented ciliary epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3191,7 +3946,13 @@ }, { "val" : "MESH:D003239" }, { - "val" : "ZFA:0009392" + "val" : "ZFA:0009392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3221,7 +3982,13 @@ }, { "val" : "WBbt:0007028" }, { - "val" : "ZFA:0007089" + "val" : "ZFA:0007089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3234,7 +4001,13 @@ "val" : "2010-09-15T03:39:21Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "embryonic cell (metazoa) on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "embryonic cell (metazoa)" @@ -3271,7 +4044,13 @@ "val" : "2010-09-22T01:57:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002363" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002363", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "keratocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3372,7 +4151,13 @@ "val" : "2011-03-06T03:28:27Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002585" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002585", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3385,6 +4170,12 @@ "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", + "pred" : "hasExactSynonym", + "val" : "RPE", + "xrefs" : [ "PMID:35835183" ] + } ], "xrefs" : [ { "val" : "BTO:0004910" }, { @@ -3404,7 +4195,13 @@ "val" : "2011-03-06T03:37:09Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002586" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002586", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal pigment epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3440,7 +4237,13 @@ "comments" : [ "Is_a interneuron, part_of UBERON:0002240." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0000778" + "val" : "ZFA:0000778", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -3458,7 +4261,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007084" + "val" : "ZFA:0007084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3512,7 +4321,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "FBbt:00005070" + "val" : "FBbt:00005070", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -3540,7 +4355,13 @@ "val" : "Mesenchymal cells are a type of undifferentiated cell that possess the ability to develop into a wide variety of other cells. These cells originate from the mesoderm during embryonic development, which gives rise to tissues such as muscles, the skeletal system, and connective and vascular structures. Mesenchymal cells primarily function as progenitor cells with exceptional renewal capabilities and are characterized by their ability to migrate, aiding in tissue repair and regeneration.\nMesenchymal cells play a critical role in the development and maintenance of various biological systems throughout the body due to their versatility and adaptability. They can differentiate into more specialized cells, including osteoblasts, adipocytes, and chondrocytes, which are essential for bone, fat, and cartilage tissues, respectively. Furthermore, they contribute to the vascular and lymphatic systems through the formation of pericytes and lymphatic endothelial cells, securing the integrity of the circulatory system.\nIn the field of regenerative medicine, mesenchymal cells, particularly mesenchymal stem cells (MSCs), are of great interest due to their unique therapeutic potential. MSCs, for instance, have been implicated in wound healing and tissue repair because of their capacity to modulate the immune response. They can secrete a range of proteins and growth factors that aid in angiogenesis, the formation of new blood vessels, and the stimulation of resident progenitor cells to aid in tissue restoration.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesenchymal cell" @@ -3639,7 +4460,13 @@ "val" : "Neural crest cells are a group of transient and highly migratory cells that originate from the neuroectoderm during the early stages of embryonic development. They are multipotent cells with an exceptional degree of plasticity, capable of differentiating into various somatic cell types and therefore play a fundamental role in the formation of various organs and tissues, making them critical contributors to the developing embryo. \nAfter the initiation of neurulation (the formation of the neural tube) neural crest cells start to undergo epithelial-to-mesenchymal transition and delaminate and migrate from the dorsal neural tube to several regions throughout the embryo. They differentiate into a range of diverse cell types, such as neurons and glial cells of the peripheral nervous system, including sensory and autonomic neurons. They also contribute to the formation of adrenal glands, pigment cells in the skin (melanocytes), cardiac structures, including parts of the heart septum and major arteries, as well as bones and cartilage of the face and skull.\nDisorders or aberrations in the development or migration of the neural crest cells can lead to serious congenital malformations, such as neurocristopathies, including Hirschsprung disease, neuroblastoma, and neurofibromatosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "neural crest cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "neural crest cell" @@ -3778,7 +4605,13 @@ "val" : "Conjunctival epithelial cells are located in the outermost layer of the conjunctiva, the transparent mucous membrane that covers the front surface of the eye (sclera) and lines the inside of the eyelids. Depending on the location, the conjunctival epithelium varies from a stratified squamous non-keratinizing epithelium (close to the lid margin) to a stratified columnar epithelium (bulbar). It consists of between two and seven layers of epithelial cells, which are organized into three main types: basal, intermediate and superficial; amongst them are goblet cells, which produce the mucous layer of the tear film, \nThe conjunctival cells play a vital role in preserving the health and functionality of the eye, contributing significantly to ocular defense mechanisms. They also participate in maintaining the ocular surface's physiological environment. Specifically, conjunctival epithelial cells serve as a physical barrier against environmental threats, such as dust, allergens, and microbes. They prevent foreign bodies from entering the eye, thanks to their tightly packed arrangement, which is integral to the eye's first line of defense. \nApart from this physical protection, these conjunctival epithelial cells are also involved in immune defense. They secrete microbicidal and immunomodulatory peptides and cytokines and can recognize and respond to pathogens through their Toll- and NOD-like receptor signaling pathways and modulate DC and lymphocyte function. \nAdditionally, conjunctival goblet cells, assist in maintaining ocular surface moisture by secreting soluble mucins for tear film production, a thin fluid layer that keeps the cornea and conjunctiva moist. This tear film lubricates the eye, protects against infections, and ensures uninterrupted, clear vision.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000432" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000432", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "conjunctival epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3804,7 +4637,13 @@ "val" : "Ciliary muscle cells are specialized contractile cells that constitute the ciliary muscle, a component of the eye in vertebrates. These cells form a ring around the iris, the eye's colored part. Ciliary muscle cells fall into the category of smooth muscle cells, characterized by their lack of the striations typical of skeletal and cardiac muscle cells. Their shape is elongated and pointed at both ends, and they occur in multi-nucleated syncytia where many cells share the same cytoplasm.\nCiliary muscle cells primarily control the eye's accommodation, adjusting the thickness and curvature of the lens to fine-tune the focus of light on the retina. When ciliary muscle cells contract, tension on the zonular fibers holding the lens in place is reduced, allowing the lens to become thicker and increase its refractive power. Conversely, when the ciliary muscle cells relax, the tension on the zonular fibers increases, causing the lens to become flatter and decrease its refractive power. This adjustment facilitates clear vision at different distances, ranging from near to far objects.\nAdditionally, ciliary muscle cells play a role in draining the eye's aqueous humor, which is the clear fluid that fills the anterior chamber of the eye between the cornea and the lens. By controlling the shape of the surrounding trabecular meshwork through muscle contractions and relaxations, ciliary muscle cells indirectly regulate intraocular pressure, a factor critical for preventing ocular conditions like glaucoma.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000443" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000443", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ciliary muscle cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3893,7 +4732,13 @@ }, { "val" : "MetaCyc:PEPTIDYLTRANSFERASE-RXN" }, { - "val" : "Reactome:R-HSA-156912" + "val" : "Reactome:R-HSA-156912", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Peptide transfer from P-site tRNA to the A-site tRNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -3901,6 +4746,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25493" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -3949,7 +4797,13 @@ "val" : "mitosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-69278" + "val" : "Reactome:R-HSA-69278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle, Mitotic" + } ] + } }, { "val" : "Wikipedia:Mitosis" } ], @@ -4139,7 +4993,13 @@ "xrefs" : [ "GOC:dph", "GOC:sdb_2009", "GOC:tb" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9823730" + "val" : "Reactome:R-HSA-9823730", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Formation of definitive endoderm" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -4517,6 +5377,9 @@ "val" : "molecular function" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is the same as GO molecular function" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -5144,7 +6007,13 @@ "val" : "protein translation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72766" + "val" : "Reactome:R-HSA-72766", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Translation" + } ] + } }, { "val" : "Wikipedia:Translation_(genetics)" } ], @@ -5177,7 +6046,13 @@ "val" : "translation initiation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72613" + "val" : "Reactome:R-HSA-72613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Initiation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5202,7 +6077,13 @@ "val" : "translation elongation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-156842" + "val" : "Reactome:R-HSA-156842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Elongation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5229,7 +6110,13 @@ "val" : "translational complex disassembly" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72764" + "val" : "Reactome:R-HSA-72764", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Termination" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5283,7 +6170,13 @@ "val" : "single-organism transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382551" + "val" : "Reactome:R-HSA-382551", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of small molecules" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -5311,7 +6204,13 @@ "val" : "ion transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-425393" + "val" : "Reactome:R-HSA-425393", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of inorganic cations/anions and amino acids/oligopeptides" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5351,15 +6250,45 @@ "val" : "sodium:neurotransmitter transport" } ], "xrefs" : [ { - 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"val" : "Reactome:R-HSA-392499" + "val" : "Reactome:R-HSA-392499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of proteins" + } ] + } }, { "val" : "Wikipedia:Protein_metabolism" } ], @@ -7553,7 +8699,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -7567,6 +8713,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/26279" }, { @@ -7583,6 +8732,7 @@ "val" : "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:18391171" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "formation of a cell surface projection" @@ -7592,6 +8742,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8213,6 +9366,9 @@ "val" : "protein-protein complex" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is not covalently bonded, which conflicts with changes to the parent definition." + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -8277,7 +9433,13 @@ "val" : "ATP hydrolysis coupled ion transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-983712" + "val" : "Reactome:R-HSA-983712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ion channel transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -8444,6 +9606,9 @@ "val" : "Wikipedia:Melanosome" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002161", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6237" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -8454,8 +9619,8 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "Any biological process involved in the maintenance of an internal steady state.", - "xrefs" : [ "GOC:jl", "ISBN:0395825172" ] + "val" : "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions.", + "xrefs" : [ "PMID:26265027" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_mouse" ], "synonyms" : [ { @@ -8478,6 +9643,9 @@ "val" : "regulation of homeostatic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/31175" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8601,7 +9769,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -8613,6 +9781,9 @@ "val" : "cellular projection" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" }, { @@ -10207,7 +11378,13 @@ "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953897" + "val" : "Reactome:R-HSA-8953897", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cellular responses to stimuli" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -10252,11 +11429,29 @@ "val" : "ATP hydrolysis coupled transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382556" + "val" : "Reactome:R-HSA-382556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ABC-family proteins mediated transport" + } ] + } }, { - "val" : "Reactome:R-HSA-425407" + "val" : "Reactome:R-HSA-425407", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "SLC-mediated transmembrane transport" + } ] + } }, { - "val" : "Reactome:R-HSA-5223345" + "val" : "Reactome:R-HSA-5223345", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Miscellaneous transport and binding events" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", @@ -10750,7 +11945,7 @@ "meta" : { "definition" : { "val" : "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.", - "xrefs" : [ "GOC:BHF", "GOC:mah", "PMID:20236620" ] + "xrefs" : [ "GOC:BHF", "PMID:12082143", "PMID:16893474", "PMID:20236620" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", @@ -10762,6 +11957,9 @@ "xrefs" : [ "GOC:BHF" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/31135" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-10-11T11:44:57Z" }, { @@ -10861,11 +12059,29 @@ "val" : "induction of apoptosis by extracellular signals" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-193681" + "val" : "Reactome:R-HSA-193681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ceramide signalling" + } ] + } }, { - "val" : "Reactome:R-HSA-204998" + "val" : "Reactome:R-HSA-204998", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell death signalling via NRAGE, NRIF and NADE" + } ] + } }, { - "val" : "Reactome:R-HSA-75157" + "val" : "Reactome:R-HSA-75157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "FasL/ CD95L signaling" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -10895,7 +12111,13 @@ "val" : "apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-75153" + "val" : "Reactome:R-HSA-75153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptotic execution phase" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -11023,7 +12245,7 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098643", - "lbl" : "fibrillar collagen", + "lbl" : "fibrillar collagen complex", "type" : "CLASS", "meta" : { "definition" : { @@ -11033,6 +12255,9 @@ "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "banded collagen fibril" + }, { + "pred" : "hasExactSynonym", + "val" : "fibrillar collagen" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -11076,14 +12301,21 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098645", - "lbl" : "collagen network", + "lbl" : "complex of network-forming collagens", "type" : "CLASS", "meta" : { "definition" : { "val" : "A supramolecular complex that consists of collagen triple helices associated to form a network.", "xrefs" : [ "GOC:dos", "PMID:21421911" ] }, + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "collagen network" + } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30938" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -11277,8 +12509,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.", - "xrefs" : [ "GOC:kmv" ] + "val" : "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { @@ -11286,6 +12517,12 @@ "val" : "cellular anatomical entity" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Overlaps with some cellular components from GO" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" }, { @@ -11534,6 +12771,29 @@ "val" : "cellular_component" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/GO_0140149", + "lbl" : "non-collagenous component of interstitial matrix", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin.", + "xrefs" : [ "PMID:21123617", "PMID:25701227", "PMID:33605520", "PMID:39223427" ] + }, + "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/29491" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30146" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2025-03-20T13:08:49Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "cellular_component" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140151", "lbl" : "solid phase of interstitial matrix", @@ -11910,6 +13170,37 @@ "val" : "Euteleostomi" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_119089", + "lbl" : "Chromadorea", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Adenophorea" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794", + "lbl" : "Ecdysozoa", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_131567", "lbl" : "cellular organisms", @@ -12129,6 +13420,32 @@ "val" : "ncbi_taxonomy" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116", + "lbl" : "Rhabditina", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119", + "lbl" : "Rhabditomorpha", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "lbl" : "Eukaryota", @@ -12174,6 +13491,46 @@ "val" : "Eukaryota" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "lbl" : "Choanoflagellata", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "choanoflagellates" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellatea" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellida" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanomonada" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanozoa" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "choanoflagellates" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + }, { + "val" : "PMID:27765632" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "lbl" : "Euarchontoglires", @@ -12366,6 +13723,19 @@ "val" : "Bilateria" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_33317", + "lbl" : "Protostomia", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_33511", "lbl" : "Deuterostomia", @@ -12625,6 +13995,32 @@ "val" : "ncbi_taxonomy" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_55879", + "lbl" : "Rhabditoidea", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_55885", + "lbl" : "Peloderinae", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6072", "lbl" : "Eumetazoa", @@ -12641,6 +14037,88 @@ "val" : "Eumetazoa" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6231", + "lbl" : "Nematoda", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "nematode" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "nematodes" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "roundworm" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "roundworms" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Nemata" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "nematodes" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6236", + "lbl" : "Rhabditida", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Strongylida" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6237", + "lbl" : "Caenorhabditis", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6243", + "lbl" : "Rhabditidae", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_7711", "lbl" : "Chordata", @@ -13322,6 +14800,21 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0001591", + "lbl" : "curvature", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.", + "xrefs" : [ "WordNet:WordNet" ] + }, + "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0001690", "lbl" : "contractile", @@ -13659,6 +15152,32 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0002254", + "lbl" : "flattened", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane.", + "xrefs" : [ "PATOC:CVS" ] + }, + "comments" : [ "Becoming flat but not necessarily completely flat." ], + "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], + "synonyms" : [ { + "pred" : "hasRelatedSynonym", + "val" : "compressed" + } ], + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0002-2061-091X" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2010-08-16T03:59:34Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002266", "lbl" : "3-D shape", @@ -15064,9 +16583,24 @@ }, { "val" : "TAO:0000107" }, { - "val" : "UMLS:C0015392" - }, { - "val" : "UMLS:C1280202" + "val" : "UMLS:C0015392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1169" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Eye" + } ] + } + }, { + "val" : "UMLS:C1280202", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1169" + } ] + } }, { "val" : "VHOG:0000275" }, { @@ -15143,7 +16677,13 @@ }, { "val" : "EMAPA:35955" }, { - "val" : "FBbt:00005155" + "val" : "FBbt:00005155", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "GAID:63" }, { @@ -15157,7 +16697,13 @@ }, { "val" : "SCTID:244485009" }, { - "val" : "UMLS:C0935626" + "val" : "UMLS:C0935626", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_of_the_Special_Sense" + } ] + } }, { "val" : "VHOG:0001407" }, { @@ -15263,7 +16809,16 @@ }, { "val" : "TGMA:0000002" }, { - "val" : "UMLS:C0018670" + "val" : "UMLS:C0018670", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1230" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Head" + } ] + } }, { "val" : "VHOG:0001644" }, { @@ -15317,7 +16872,13 @@ }, { "val" : "TAO:0005425" }, { - "val" : "UMLS:C0036760" + "val" : "UMLS:C0036760", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Serosa" + } ] + } }, { "val" : "Wikipedia:Serous_membrane" }, { @@ -15403,7 +16964,13 @@ "xrefs" : [ { "val" : "AAO:0011123" }, { - "val" : "FBbt:00100314" + "val" : "FBbt:00100314", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:30320" }, { @@ -15413,7 +16980,13 @@ }, { "val" : "TAO:0005171" }, { - "val" : "UMLS:C0687028" + "val" : "UMLS:C0687028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Duct" + } ] + } }, { "val" : "Wikipedia:Duct_(anatomy)" }, { @@ -15493,7 +17066,13 @@ }, { "val" : "FAO:0000001" }, { - "val" : "FBbt:00007001" + "val" : "FBbt:00007001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:305751" }, { @@ -15578,7 +17157,13 @@ }, { "val" : "SCTID:272625005" }, { - "val" : "UMLS:C0178784" + "val" : "UMLS:C0178784", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ" + } ] + } }, { "val" : "WBbt:0003760" }, { @@ -15586,7 +17171,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33090" @@ -15706,47 +17297,161 @@ }, { "val" : "BilaDO:0000004" }, { - "val" : "BtauDv:0000078" - }, { - "val" : "CfamDv:0000007" - }, { - "val" : "ChirDv:0000014" - }, { - "val" : "DpseDv:0000005" - }, { - "val" : "DsimDv:0000005" + "val" : "BtauDv:0000078", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001272" }, { - "val" : "EcabDv:0000007" + "val" : "EcabDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005369" }, { - "val" : "FcatDv:0000007" - }, { - "val" : "GgalDv:0000076" - }, { - "val" : "GgorDv:0000032" - }, { - "val" : "HsapDv:0010000" - }, { - "val" : "MmulDv:0000052" - }, { - "val" : "MmusDv:0000092" - }, { - "val" : "OanaDv:0000007" - }, { - "val" : "OariDv:0000024" - }, { - "val" : "PpanDv:0000041" - }, { - "val" : "PtroDv:0000052" - }, { - "val" : "RnorDv:0000061" - }, { - "val" : "SsalDv:0000040" - }, { - "val" : "SscrDv:0000084" + "val" : "FcatDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000076", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000032", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0010000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000041", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000061", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000041" }, { @@ -15777,65 +17482,203 @@ "val" : "embryogenesis" } ], "xrefs" : [ { - "val" : "AcarDv:0000002" + "val" : "AcarDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BilaDO:0000002" }, { - "val" : "BtauDv:0000002" - }, { - "val" : "CfamDv:0000002" - }, { - "val" : "ChirDv:0000002" - }, { - "val" : "CporDv:0000002" - }, { - "val" : "DpseDv:0000002" - }, { - "val" : "DsimDv:0000002" + "val" : "BtauDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EV:0300001" }, { - "val" : "EcabDv:0000002" + "val" : "EcabDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005289" }, { "val" : "FMA:72652" }, { - "val" : "FcatDv:0000002" - }, { - "val" : "GgalDv:0000002" - }, { - "val" : "GgorDv:0000002" - }, { - "val" : "HsapDv:0000045" - }, { - "val" : "MdomDv:0000002" - }, { - "val" : "MmulDv:0000002" - }, { - "val" : "MmusDv:0000042" + "val" : "FcatDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000045", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000042", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000000" }, { "val" : "OGES:000022" }, { - "val" : "OanaDv:0000002" - }, { - "val" : "OariDv:0000002" - }, { - "val" : "OcunDv:0000002" - }, { - "val" : "PpanDv:0000002" - }, { - "val" : "PtroDv:0000002" - }, { - "val" : "RnorDv:0000002" + "val" : "OanaDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "SCTID:296280003" }, { - "val" : "SsalDv:0000002" - }, { - "val" : "SscrDv:0000002" + "val" : "SsalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000003" }, { @@ -15905,7 +17748,13 @@ }, { "val" : "SCTID:25087005" }, { - "val" : "UMLS:C1518256" + "val" : "UMLS:C1518256", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System_Part" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -15943,7 +17792,13 @@ }, { "val" : "SCTID:118966000" }, { - "val" : "UMLS:C1519343" + "val" : "UMLS:C1519343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System_Part" + } ] + } }, { "val" : "galen:ComplexSkeletalStructure" } ], @@ -15991,7 +17846,13 @@ }, { "val" : "NCIT:C34309" }, { - "val" : "UMLS:C1515087" + "val" : "UMLS:C1515087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Surface_Ectoderm" + } ] + } }, { "val" : "Wikipedia:External_ectoderm" } ], @@ -16034,7 +17895,13 @@ }, { "val" : "OGES:000024" }, { - "val" : "SsalDv:0000038" + "val" : "SsalDv:0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000022" }, { @@ -16104,55 +17971,193 @@ "val" : "lifespan" } ], "xrefs" : [ { - "val" : "AcarDv:0000001" - }, { - "val" : "BtauDv:0000001" - }, { - "val" : "CfamDv:0000001" - }, { - "val" : "ChirDv:0000001" - }, { - "val" : "CporDv:0000001" - }, { - "val" : "DpseDv:0000001" - }, { - "val" : "DsimDv:0000001" - }, { - "val" : "EcabDv:0000001" + "val" : "AcarDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "BtauDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "EcabDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00000000" }, { - "val" : "FcatDv:0000001" - }, { - "val" : "GgalDv:0000001" - }, { - "val" : "GgorDv:0000001" - }, { - "val" : "HsapDv:0000001" - }, { - "val" : "MdomDv:0000001" - }, { - "val" : "MmulDv:0000001" - }, { - "val" : "MmusDv:0000001" + "val" : "FcatDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000011" }, { - "val" : "OanaDv:0000001" - }, { - "val" : "OariDv:0000001" - }, { - "val" : "OcunDv:0000001" - }, { - "val" : "PpanDv:0000001" - }, { - "val" : "PtroDv:0000001" - }, { - "val" : "RnorDv:0000001" - }, { - "val" : "SsalDv:0000001" - }, { - "val" : "SscrDv:0000001" + "val" : "OanaDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "ncithesaurus:Life" } ], @@ -16191,63 +18196,201 @@ "val" : "stage" } ], "xrefs" : [ { - "val" : "AcarDv:0000000" + "val" : "AcarDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BILS:0000105" }, { - "val" : "BtauDv:0000000" - }, { - "val" : "CfamDv:0000000" - }, { - "val" : "ChirDv:0000000" - }, { - "val" : "CporDv:0000000" - }, { - "val" : "DpseDv:0000000" - }, { - "val" : "DsimDv:0000000" + "val" : "BtauDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0000399" }, { - "val" : "EcabDv:0000000" + "val" : "EcabDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00007012" }, { "val" : "FMA:24120" }, { - "val" : "FcatDv:0000000" - }, { - "val" : "GgalDv:0000000" - }, { - "val" : "GgorDv:0000000" - }, { - "val" : "HsapDv:0000000" + "val" : "FcatDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D008018" }, { - "val" : "MdomDv:0000000" - }, { - "val" : "MmulDv:0000000" - }, { - "val" : "MmusDv:0000000" - }, { - "val" : "OanaDv:0000000" - }, { - "val" : "OariDv:0000000" - }, { - "val" : "OcunDv:0000000" + "val" : "MdomDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000090" }, { - "val" : "PpanDv:0000000" - }, { - "val" : "PtroDv:0000000" - }, { - "val" : "RnorDv:0000000" - }, { - "val" : "SsalDv:0000000" - }, { - "val" : "SscrDv:0000000" + "val" : "PpanDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000002" }, { @@ -16318,7 +18461,13 @@ }, { "val" : "BilaDO:0000005" }, { - "val" : "ChirDv:0000003" + "val" : "ChirDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001322" }, { @@ -16326,21 +18475,57 @@ }, { "val" : "FBdv:00005288" }, { - "val" : "HsapDv:0000003" - }, { - "val" : "MmusDv:0000003" + "val" : "HsapDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "NCIT:C12601" }, { - "val" : "OariDv:0000009" + "val" : "OariDv:0000009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000100" }, { - "val" : "RnorDv:0000048" - }, { - "val" : "SsalDv:0000003" - }, { - "val" : "SscrDv:0000087" + "val" : "RnorDv:0000048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "VHOG:0000745" }, { @@ -16373,33 +18558,81 @@ }, { "val" : "BilaDO:0000006" }, { - "val" : "ChirDv:0000004" + "val" : "ChirDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001290" }, { "val" : "FBdv:00000054" }, { - "val" : "GgalDv:0000064" - }, { - "val" : "HsapDv:0000005" + "val" : "GgalDv:0000064", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D002970" }, { - "val" : "MmusDv:0000004" + "val" : "MmusDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000015" }, { "val" : "OGES:000020" }, { - "val" : "OariDv:0000010" + "val" : "OariDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000200" }, { - "val" : "RnorDv:0000049" - }, { - "val" : "SsalDv:0000004" - }, { - "val" : "SscrDv:0000088" + "val" : "RnorDv:0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000088", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Cleavage_(embryo)" }, { @@ -16427,15 +18660,39 @@ }, { "val" : "BilaDO:0000007" }, { - "val" : "ChirDv:0000010" + "val" : "ChirDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001282" }, { - "val" : "GgalDv:0000091" - }, { - "val" : "HsapDv:0000006" - }, { - "val" : "MmusDv:0000007" + "val" : "GgalDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000003" }, { @@ -16443,13 +18700,37 @@ }, { "val" : "OGES:000021" }, { - "val" : "OariDv:0000025" - }, { - "val" : "RnorDv:0000054" - }, { - "val" : "SsalDv:0000012" - }, { - "val" : "SscrDv:0000089" + "val" : "OariDv:0000025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000005" }, { @@ -16510,29 +18791,77 @@ }, { "val" : "BilaDO:0000008" }, { - "val" : "ChirDv:0000011" + "val" : "ChirDv:0000011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001296" }, { "val" : "FBdv:00005317" }, { - "val" : "GgalDv:0000092" - }, { - "val" : "HsapDv:0000010" - }, { - "val" : "MmusDv:0000013" + "val" : "GgalDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000004" }, { "val" : "OGES:000019" }, { - "val" : "OariDv:0000026" - }, { - "val" : "RnorDv:0000005" - }, { - "val" : "SsalDv:0000016" - }, { - "val" : "SscrDv:0000090" + "val" : "OariDv:0000026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000010" }, { @@ -16559,19 +18888,61 @@ }, { "val" : "BilaDO:0000009" }, { - "val" : "ChirDv:0000012" - }, { - "val" : "GgalDv:0000093" - }, { - "val" : "HsapDv:0000012" - }, { - "val" : "MmusDv:0000017" - }, { - "val" : "OariDv:0000027" - }, { - "val" : "RnorDv:0000007" - }, { - "val" : "SscrDv:0000091" + "val" : "ChirDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "XAO:1000006" } ], @@ -16604,25 +18975,73 @@ }, { "val" : "BilaDO:0000010" }, { - "val" : "ChirDv:0000013" - }, { - "val" : "GgalDv:0000094" - }, { - "val" : "HsapDv:0000015" - }, { - "val" : "MmusDv:0000018" + "val" : "ChirDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000018", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000005" }, { "val" : "OGES:000032" }, { - "val" : "OariDv:0000028" - }, { - "val" : "RnorDv:0000055" - }, { - "val" : "SsalDv:0000022" - }, { - "val" : "SscrDv:0000086" + "val" : "OariDv:0000028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Organogenesis" } ], @@ -16660,7 +19079,13 @@ "xrefs" : [ { "val" : "CARO:0001001" }, { - "val" : "FBbt:00005099" + "val" : "FBbt:00005099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "NLX:147821" } ], @@ -16773,7 +19198,13 @@ }, { "val" : "EMAPA:16262" }, { - "val" : "FBbt:00003126" + "val" : "FBbt:00003126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:49184" }, { @@ -16889,7 +19320,13 @@ }, { "val" : "TAO:0000007" }, { - "val" : "UMLS:C0005767" + "val" : "UMLS:C0005767", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood" + } ] + } }, { "val" : "VHOG:0000224" }, { @@ -17079,7 +19516,13 @@ "xrefs" : [ { "val" : "BTO:0001837" }, { - "val" : "EMAPA:37950" + "val" : "EMAPA:37950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:62889" }, { @@ -17148,7 +19591,13 @@ }, { "val" : "NCIT:C34062" }, { - "val" : "UMLS:C1516992" + "val" : "UMLS:C1516992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland_Fluid_or_Secretion" + } ] + } }, { "val" : "galen:Secretion" } ], @@ -17203,7 +19652,13 @@ }, { "val" : "EMAPA:35178" }, { - "val" : "FBbt:00007019" + "val" : "FBbt:00007019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9669" }, { @@ -17277,7 +19732,13 @@ }, { "val" : "EHDAA2:0003005" }, { - "val" : "FBbt:00007017" + "val" : "FBbt:00007017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:5897" }, { @@ -17289,7 +19750,13 @@ }, { "val" : "TGMA:0001825" }, { - "val" : "UMLS:C0524461" + "val" : "UMLS:C0524461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lumen_Space" + } ] + } }, { "val" : "VHOG:0001728" }, { @@ -17332,7 +19799,13 @@ }, { "val" : "EHDAA2:0003006" }, { - "val" : "FBbt:00007016" + "val" : "FBbt:00007016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67165" }, { @@ -17384,7 +19857,13 @@ }, { "val" : "EHDAA2:0003007" }, { - "val" : "FBbt:00007015" + "val" : "FBbt:00007015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67112" }, { @@ -17464,7 +19943,13 @@ }, { "val" : "EV:0100000" }, { - "val" : "FBbt:00004856" + "val" : "FBbt:00004856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7149" }, { @@ -17480,7 +19965,13 @@ }, { "val" : "TGMA:0001831" }, { - "val" : "UMLS:C0460002" + "val" : "UMLS:C0460002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_System" + } ] + } }, { "val" : "VHOG:0001725" }, { @@ -17578,7 +20069,13 @@ }, { "val" : "EV:0100016" }, { - "val" : "FBbt:00000001" + "val" : "FBbt:00000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:256135" }, { @@ -17670,7 +20167,13 @@ }, { "val" : "EMAPA:36031" }, { - "val" : "FBbt:00007009" + "val" : "FBbt:00007009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7153" }, { @@ -17690,7 +20193,13 @@ }, { "val" : "TGMA:0001840" }, { - "val" : "UMLS:C0229962" + "val" : "UMLS:C0229962", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Body_Part" + } ] + } }, { "val" : "VHOG:0001758" }, { @@ -17746,7 +20255,13 @@ }, { "val" : "EHDAA2:0003040" }, { - "val" : "FBbt:00007013" + "val" : "FBbt:00007013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:63863" }, { @@ -17785,7 +20300,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007277" + "val" : "FBbt:00007277", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "VHOG:0001737" } ], @@ -17844,7 +20365,13 @@ }, { "val" : "EMAPA:35868" }, { - "val" : "FBbt:00007003" + "val" : "FBbt:00007003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9637" }, { @@ -17860,7 +20387,13 @@ }, { "val" : "TGMA:0001844" }, { - "val" : "UMLS:C0040300" + "val" : "UMLS:C0040300", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Tissue" + } ] + } }, { "val" : "VHOG:0001757" }, { @@ -17916,7 +20449,13 @@ }, { "val" : "EHDAA2:0003055" }, { - "val" : "FBbt:00007010" + "val" : "FBbt:00007010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000055" }, { @@ -17982,7 +20521,13 @@ }, { "val" : "EMAPA:32738" }, { - "val" : "FBbt:00007005" + "val" : "FBbt:00007005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9639" }, { @@ -18000,7 +20545,13 @@ }, { "val" : "TAO:0001486" }, { - "val" : "UMLS:C0014609" + "val" : "UMLS:C0014609", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Epithelium" + } ] + } }, { "val" : "VHOG:0000387" }, { @@ -18059,7 +20610,13 @@ }, { "val" : "TAO:0001494" }, { - "val" : "UMLS:C0682575" + "val" : "UMLS:C0682575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stratified_Epithelium" + } ] + } }, { "val" : "Wikipedia:Stratified_epithelium" }, { @@ -18112,7 +20669,13 @@ }, { "val" : "TAO:0001498" }, { - "val" : "UMLS:C0836133" + "val" : "UMLS:C0836133", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_squamous_epithelium" }, { @@ -18266,7 +20829,13 @@ }, { "val" : "TAO:0001495" }, { - "val" : "UMLS:C0682574" + "val" : "UMLS:C0682574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Epithelium" + } ] + } }, { "val" : "XAO:0004007" }, { @@ -18366,7 +20935,13 @@ }, { "val" : "EMAPA:16039" }, { - "val" : "FBbt:00000052" + "val" : "FBbt:00000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69068" }, { @@ -18384,7 +20959,13 @@ }, { "val" : "SCTID:57991002" }, { - "val" : "UMLS:C0013935" + "val" : "UMLS:C0013935", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryo" + } ] + } }, { "val" : "VHOG:0001766" }, { @@ -18446,7 +21027,13 @@ }, { "val" : "EMAPA:36033" }, { - "val" : "FBbt:00000110" + "val" : "FBbt:00000110", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69069" }, { @@ -18460,9 +21047,21 @@ }, { "val" : "TAO:0001122" }, { - "val" : "UMLS:C0920502" - }, { - "val" : "UMLS:C1708239" + "val" : "UMLS:C0920502", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Tissue" + } ] + } + }, { + "val" : "UMLS:C1708239", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Germinal_Layer" + } ] + } }, { "val" : "VHOG:0001223" }, { @@ -18509,7 +21108,13 @@ }, { "val" : "EV:0100003" }, { - "val" : "FBbt:00000111" + "val" : "FBbt:00000111", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69070" }, { @@ -18529,7 +21134,13 @@ }, { "val" : "TAO:0000016" }, { - "val" : "UMLS:C0013574" + "val" : "UMLS:C0013574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ectoderm" + } ] + } }, { "val" : "VHOG:0000153" }, { @@ -18580,7 +21191,13 @@ }, { "val" : "EV:0100005" }, { - "val" : "FBbt:00000125" + "val" : "FBbt:00000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69071" }, { @@ -18598,7 +21215,13 @@ }, { "val" : "TAO:0000017" }, { - "val" : "UMLS:C0014144" + "val" : "UMLS:C0014144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endoderm" + } ] + } }, { "val" : "VHOG:0000154" }, { @@ -18664,7 +21287,13 @@ }, { "val" : "EV:0100006" }, { - "val" : "FBbt:00000126" + "val" : "FBbt:00000126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69072" }, { @@ -18682,7 +21311,13 @@ }, { "val" : "TAO:0000041" }, { - "val" : "UMLS:C0025485" + "val" : "UMLS:C0025485", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesoderm" + } ] + } }, { "val" : "VHOG:0000152" }, { @@ -18752,7 +21387,13 @@ }, { "val" : "EMAPA:16263" }, { - "val" : "FBbt:00000439" + "val" : "FBbt:00000439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:295846" }, { @@ -18762,7 +21403,13 @@ }, { "val" : "TGMA:0000135" }, { - "val" : "UMLS:C1514977" + "val" : "UMLS:C1514977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stomodeum" + } ] + } }, { "val" : "Wikipedia:Stomodeum" }, { @@ -18885,7 +21532,16 @@ }, { "val" : "TAO:0000435" }, { - "val" : "UMLS:C0029130" + "val" : "UMLS:C0029130", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1640" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Nerve" + } ] + } }, { "val" : "VHOG:0000543" }, { @@ -18895,7 +21551,13 @@ }, { "val" : "ZFA:0000435" }, { - "val" : "neuronames:289" + "val" : "neuronames:289", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1640" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -18972,7 +21634,13 @@ }, { "val" : "TAO:0000114" }, { - "val" : "UMLS:C0018787" + "val" : "UMLS:C0018787", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Heart" + } ] + } }, { "val" : "VHOG:0000276" }, { @@ -19065,7 +21733,13 @@ }, { "val" : "EV:0100164" }, { - "val" : "FBbt:00005095" + "val" : "FBbt:00005095", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:50801" }, { @@ -19093,9 +21767,24 @@ }, { "val" : "TAO:0000008" }, { - "val" : "UMLS:C0006104" - }, { - "val" : "UMLS:C1269537" + "val" : "UMLS:C0006104", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:796" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Brain" + } ] + } + }, { + "val" : "UMLS:C1269537", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:796" + } ] + } }, { "val" : "VHOG:0000157" }, { @@ -19107,7 +21796,13 @@ }, { "val" : "galen:Brain" }, { - "val" : "neuronames:21" + "val" : "neuronames:21", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:796" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -19238,7 +21933,16 @@ }, { "val" : "TAO:0000556" }, { - "val" : "UMLS:C0029126" + "val" : "UMLS:C0029126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1416" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Chiasm" + } ] + } }, { "val" : "VHOG:0000190" }, { @@ -19248,7 +21952,13 @@ }, { "val" : "ZFA:0000556" }, { - "val" : "neuronames:459" + "val" : "neuronames:459", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1416" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -19318,7 +22028,13 @@ }, { "val" : "TAO:0000640" }, { - "val" : "UMLS:C0010031" + "val" : "UMLS:C0010031", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cornea" + } ] + } }, { "val" : "VHOG:0000164" }, { @@ -19411,7 +22127,13 @@ }, { "val" : "TAO:0000035" }, { - "val" : "UMLS:C0023317" + "val" : "UMLS:C0023317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Crystalline_Lens" + } ] + } }, { "val" : "VHOG:0000169" }, { @@ -19503,9 +22225,24 @@ }, { "val" : "TAO:0000152" }, { - "val" : "UMLS:C0035298" - }, { - "val" : "UMLS:C1278894" + "val" : "UMLS:C0035298", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1153" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Retina" + } ] + } + }, { + "val" : "UMLS:C1278894", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1153" + } ] + } }, { "val" : "VHOG:0000229" }, { @@ -19560,7 +22297,13 @@ }, { "val" : "EV:0100336" }, { - "val" : "FBbt:00005162" + "val" : "FBbt:00005162", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "GAID:69" }, { @@ -19639,7 +22382,13 @@ }, { "val" : "TAO:0000367" }, { - "val" : "UMLS:C0022417" + "val" : "UMLS:C0022417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint" + } ] + } }, { "val" : "VHOG:0001276" }, { @@ -19692,7 +22441,13 @@ }, { "val" : "EFO:0000793" }, { - "val" : "FBbt:00005055" + "val" : "FBbt:00005055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7152" }, { @@ -19753,7 +22508,13 @@ }, { "val" : "CALOHA:TS-2103" }, { - "val" : "MESH:D002319" + "val" : "MESH:D002319", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "VHOG:0001248" }, { @@ -19761,7 +22522,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6073" @@ -19833,7 +22600,13 @@ }, { "val" : "TAO:0000548" }, { - "val" : "UMLS:C0026845" + "val" : "UMLS:C0026845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle" + } ] + } }, { "val" : "VSAO:0005038" }, { @@ -19896,7 +22669,13 @@ }, { "val" : "EV:0100162" }, { - "val" : "FBbt:00005093" + "val" : "FBbt:00005093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7157" }, { @@ -19916,7 +22695,13 @@ }, { "val" : "TAO:0000396" }, { - "val" : "UMLS:C0027763" + "val" : "UMLS:C0027763", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System" + } ] + } }, { "val" : "VHOG:0000402" }, { @@ -20000,7 +22785,13 @@ }, { "val" : "EV:0100163" }, { - "val" : "FBbt:00005094" + "val" : "FBbt:00005094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:55675" }, { @@ -20018,7 +22809,16 @@ }, { "val" : "TAO:0000012" }, { - "val" : "UMLS:C0927232" + "val" : "UMLS:C0927232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1099" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Central_Nervous_System" + } ] + } }, { "val" : "VHOG:0000293" }, { @@ -20032,7 +22832,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -20079,7 +22885,13 @@ }, { "val" : "EV:0100304" }, { - "val" : "FBbt:00005100" + "val" : "FBbt:00005100", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:83847" }, { @@ -20139,7 +22951,13 @@ }, { "val" : "TGMA:0000088" }, { - "val" : "UMLS:C1185741" + "val" : "UMLS:C1185741", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Fascicle" + } ] + } }, { "val" : "Wikipedia:Nervous_system_fascicle" } ], @@ -20208,7 +23026,13 @@ }, { "val" : "EMAPA:16192" }, { - "val" : "FBbt:00007692" + "val" : "FBbt:00007692", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:75259" }, { @@ -20279,7 +23103,13 @@ }, { "val" : "EHDAA2:0003171" }, { - "val" : "FBbt:00005495" + "val" : "FBbt:00005495", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86589" }, { @@ -20287,7 +23117,13 @@ }, { "val" : "NCIT:C34275" }, { - "val" : "UMLS:C0678727" + "val" : "UMLS:C0678727", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium" + } ] + } }, { "val" : "Wikipedia:Primordium" }, { @@ -20351,7 +23187,13 @@ }, { "val" : "TAO:0001135" }, { - "val" : "UMLS:C0231024" + "val" : "UMLS:C0231024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Tube" + } ] + } }, { "val" : "VHOG:0000307" }, { @@ -20396,7 +23238,13 @@ }, { "val" : "EHDAA2:0002229" }, { - "val" : "FBbt:10000000" + "val" : "FBbt:10000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:62955" }, { @@ -20410,7 +23258,13 @@ }, { "val" : "TGMA:0001822" }, { - "val" : "UMLS:C1515976" + "val" : "UMLS:C1515976", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Structure_System_or_Substance" + } ] + } }, { "val" : "WBbt:0000100" }, { @@ -20466,7 +23320,13 @@ }, { "val" : "TAO:0005154" }, { - "val" : "UMLS:C0039097" + "val" : "UMLS:C0039097", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Synovial_Fluid" + } ] + } }, { "val" : "Wikipedia:Synovial_fluid" }, { @@ -20550,7 +23410,13 @@ }, { "val" : "TAO:0005274" }, { - "val" : "UMLS:C1267092" + "val" : "UMLS:C1267092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Smooth_Muscle_Tissue" + } ] + } }, { "val" : "VHOG:0001246" }, { @@ -20615,7 +23481,13 @@ }, { "val" : "SCTID:361918002" }, { - "val" : "UMLS:C0086610" + "val" : "UMLS:C0086610", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesothelium" + } ] + } }, { "val" : "Wikipedia:Mesothelium" } ], @@ -20666,7 +23538,13 @@ }, { "val" : "SCTID:123961009" }, { - "val" : "UMLS:C0004600" + "val" : "UMLS:C0004600", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Back" + } ] + } }, { "val" : "Wikipedia:Dorsum_(anatomy)" }, { @@ -20723,7 +23601,13 @@ }, { "val" : "TAO:0000434" }, { - "val" : "UMLS:C0037253" + "val" : "UMLS:C0037253", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System" + } ] + } }, { "val" : "VHOG:0001254" }, { @@ -20813,7 +23697,13 @@ }, { "val" : "SCTID:302549007" }, { - "val" : "UMLS:C0015450" + "val" : "UMLS:C0015450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Face" + } ] + } }, { "val" : "Wikipedia:Face" }, { @@ -20858,7 +23748,13 @@ "xrefs" : [ "Wikipedia:Articular_capsule" ] } ], "xrefs" : [ { - "val" : "EMAPA:37621" + "val" : "EMAPA:37621", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:34836" }, { @@ -20874,7 +23770,13 @@ }, { "val" : "SCTID:182238002" }, { - "val" : "UMLS:C0206207" + "val" : "UMLS:C0206207", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint_Capsule" + } ] + } }, { "val" : "Wikipedia:Articular_capsule" }, { @@ -20940,13 +23842,25 @@ }, { "val" : "EMAPA:16247" }, { - "val" : "FBbt:00003125" + "val" : "FBbt:00003125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45615" }, { "val" : "MA:0000917" }, { - "val" : "MESH:D041981" + "val" : "MESH:D041981", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C34082" }, { @@ -20954,7 +23868,13 @@ }, { "val" : "TGMA:0001819" }, { - "val" : "UMLS:C0017189" + "val" : "UMLS:C0017189", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrointestinal_Tract" + } ] + } }, { "val" : "VHOG:0000309" }, { @@ -20966,10 +23886,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1371/journal.pone.0016309" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -21019,7 +23951,13 @@ }, { "val" : "SCTID:280862009" }, { - "val" : "UMLS:C0559230" + "val" : "UMLS:C0559230", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ciliary_Muscle" + } ] + } }, { "val" : "Wikipedia:Ciliary_muscle" } ], @@ -21050,7 +23988,13 @@ "xrefs" : [ "ZFA:0005145" ] } ], "xrefs" : [ { - "val" : "EMAPA:37474" + "val" : "EMAPA:37474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100146" }, { @@ -21140,7 +24084,13 @@ }, { "val" : "TAO:0000005" }, { - "val" : "UMLS:C0003842" + "val" : "UMLS:C0003842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Artery" + } ] + } }, { "val" : "VHOG:0001251" }, { @@ -21229,7 +24179,13 @@ }, { "val" : "TAO:0000082" }, { - "val" : "UMLS:C0042449" + "val" : "UMLS:C0042449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vein" + } ] + } }, { "val" : "VHOG:0001743" }, { @@ -21303,7 +24259,13 @@ }, { "val" : "SCTID:265782007" }, { - "val" : "UMLS:C0015426" + "val" : "UMLS:C0015426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Eyelid" + } ] + } }, { "val" : "VHOG:0000016" }, { @@ -21372,7 +24334,13 @@ }, { "val" : "SCTID:181160009" }, { - "val" : "UMLS:C0003151" + "val" : "UMLS:C0003151", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anterior_Chamber_of_the_Eye" + } ] + } }, { "val" : "VHOG:0001431" }, { @@ -21443,7 +24411,13 @@ }, { "val" : "SCTID:280648000" }, { - "val" : "UMLS:C0042160" + "val" : "UMLS:C0042160", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Uvea" + } ] + } }, { "val" : "Wikipedia:Uvea" } ], @@ -21452,7 +24426,13 @@ "val" : "TODO - check child terms, isa vs partof. See also MA:0001284 ! tunica vasculosa plexus" }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7955" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7955", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1177/0192623311409597" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "uvea" @@ -21511,7 +24491,13 @@ }, { "val" : "TAO:0001238" }, { - "val" : "UMLS:C0022077" + "val" : "UMLS:C0022077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Iris" + } ] + } }, { "val" : "VHOG:0000101" }, { @@ -21622,7 +24608,13 @@ }, { "val" : "TAO:0002187" }, { - "val" : "UMLS:C0459875" + "val" : "UMLS:C0459875", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Corneal_Epithelium" + } ] + } }, { "val" : "Wikipedia:Corneal_epithelium" }, { @@ -21675,7 +24667,13 @@ }, { "val" : "SCTID:181163006" }, { - "val" : "UMLS:C0036410" + "val" : "UMLS:C0036410", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclera" + } ] + } }, { "val" : "VHOG:0001274" }, { @@ -21746,7 +24744,13 @@ }, { "val" : "SCTID:263340007" }, { - "val" : "UMLS:C0008779" + "val" : "UMLS:C0008779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ciliary_Body" + } ] + } }, { "val" : "VHOG:0000102" }, { @@ -21834,7 +24838,13 @@ }, { "val" : "TAO:0005229" }, { - "val" : "UMLS:C0008520" + "val" : "UMLS:C0008520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Choroid" + } ] + } }, { "val" : "VHOG:0001568" }, { @@ -21903,7 +24913,13 @@ }, { "val" : "TAO:0002189" }, { - "val" : "UMLS:C0010040" + "val" : "UMLS:C0010040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Corneal_Stroma" + } ] + } }, { "val" : "Wikipedia:Corneal_stroma" }, { @@ -21951,7 +24967,13 @@ }, { "val" : "SCTID:280870004" }, { - "val" : "UMLS:C0459736" + "val" : "UMLS:C0459736", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ciliary_Epithelium" + } ] + } }, { "val" : "Wikipedia:Ciliary_body#Ciliary_epithelium" } ], @@ -22001,7 +25023,13 @@ }, { "val" : "SCTID:280657006" }, { - "val" : "UMLS:C0459649" + "val" : "UMLS:C0459649", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Retina_Layer" + } ] + } }, { "val" : "XAO:0000266" } ], @@ -22106,7 +25134,13 @@ }, { "val" : "TAO:0000144" }, { - "val" : "UMLS:C0035322" + "val" : "UMLS:C0035322", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Retinal_Pigment_Epithelium" + } ] + } }, { "val" : "VHOG:0000536" }, { @@ -22169,7 +25203,13 @@ }, { "val" : "TAO:0000143" }, { - "val" : "UMLS:C0229206" + "val" : "UMLS:C0229206", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Layer_of_the_Rods_and_Cones" + } ] + } }, { "val" : "VHOG:0001165" }, { @@ -22254,7 +25294,13 @@ }, { "val" : "TAO:0001331" }, { - "val" : "UMLS:C1518685" + "val" : "UMLS:C1518685", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Outer_Limiting_Membrane" + } ] + } }, { "val" : "Wikipedia:External_limiting_membrane" }, { @@ -22332,7 +25378,13 @@ }, { "val" : "TAO:0001464" }, { - "val" : "UMLS:C0229210" + "val" : "UMLS:C0229210", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Outer_Nuclear_Layer_of_Retina" + } ] + } }, { "val" : "VHOG:0001170" }, { @@ -22410,7 +25462,13 @@ }, { "val" : "TAO:0001330" }, { - "val" : "UMLS:C0229217" + "val" : "UMLS:C0229217", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Outer_Plexiform_Layer" + } ] + } }, { "val" : "VHOG:0001171" }, { @@ -22490,7 +25548,13 @@ }, { "val" : "TAO:0000119" }, { - "val" : "UMLS:C0229211" + "val" : "UMLS:C0229211", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Inner_Nuclear_Layer" + } ] + } }, { "val" : "VHOG:0001167" }, { @@ -22733,7 +25797,13 @@ }, { "val" : "TAO:0001029" }, { - "val" : "UMLS:C1512783" + "val" : "UMLS:C1512783", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Inner_Limiting_Membrane" + } ] + } }, { "val" : "Wikipedia:Inner_limiting_membrane" }, { @@ -22817,7 +25887,13 @@ }, { "val" : "TAO:0001329" }, { - "val" : "UMLS:C0229221" + "val" : "UMLS:C0229221", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Inner_Plexiform_Layer" + } ] + } }, { "val" : "VHOG:0001168" }, { @@ -22876,7 +25952,13 @@ }, { "val" : "SCTID:280587006" }, { - "val" : "UMLS:C0003662" + "val" : "UMLS:C0003662", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Aqueous_Humor" + } ] + } }, { "val" : "VHOG:0000548" }, { @@ -22953,11 +26035,23 @@ }, { "val" : "MA:0001286" }, { - "val" : "MESH:D014822" + "val" : "MESH:D014822", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C13323" }, { - "val" : "UMLS:C0229096" + "val" : "UMLS:C0229096", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vitreous_Humor" + } ] + } }, { "val" : "VHOG:0000795" }, { @@ -22995,7 +26089,13 @@ }, { "val" : "SCTID:181170006" }, { - "val" : "UMLS:C0042905" + "val" : "UMLS:C0042905", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vitreous_Body" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -23048,7 +26148,13 @@ "xrefs" : [ { "val" : "BTO:0002087" }, { - "val" : "EMAPA:37805" + "val" : "EMAPA:37805", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:58848" }, { @@ -23056,7 +26162,13 @@ }, { "val" : "NCIT:C33885" }, { - "val" : "UMLS:C0229095" + "val" : "UMLS:C0229095", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vitreous_Chamber" + } ] + } }, { "val" : "Wikipedia:Vitreous_chamber" } ] @@ -23109,7 +26221,13 @@ }, { "val" : "SCTID:280658001" }, { - "val" : "UMLS:C0003153" + "val" : "UMLS:C0003153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anterior_Eye_Segment" + } ] + } }, { "val" : "Wikipedia:Anterior_segment_of_eyeball" }, { @@ -23169,7 +26287,13 @@ }, { "val" : "SCTID:280659009" }, { - "val" : "UMLS:C0278450" + "val" : "UMLS:C0278450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Posterior_Eye_Segment" + } ] + } }, { "val" : "Wikipedia:Posterior_segment_of_eyeball" }, { @@ -23236,7 +26360,13 @@ }, { "val" : "SCTID:181161008" }, { - "val" : "UMLS:C0009758" + "val" : "UMLS:C0009758", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conjunctiva" + } ] + } }, { "val" : "Wikipedia:Conjunctiva" }, { @@ -23310,7 +26440,16 @@ }, { "val" : "TAO:0000109" }, { - "val" : "UMLS:C0085140" + "val" : "UMLS:C0085140", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1509" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Fore-Brain" + } ] + } }, { "val" : "VHOG:0000383" }, { @@ -23320,7 +26459,13 @@ }, { "val" : "ZFA:0000109" }, { - "val" : "neuronames:27" + "val" : "neuronames:27", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1509" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -23403,7 +26548,16 @@ }, { "val" : "TAO:0000128" }, { - "val" : "UMLS:C0025462" + "val" : "UMLS:C0025462", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1667" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesencephalon" + } ] + } }, { "val" : "VHOG:0000069" }, { @@ -23413,7 +26567,13 @@ }, { "val" : "ZFA:0000128" }, { - "val" : "neuronames:462" + "val" : "neuronames:462", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1667" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -23532,7 +26692,16 @@ }, { "val" : "TAO:0000101" }, { - "val" : "UMLS:C0012144" + "val" : "UMLS:C0012144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1503" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Diencephalon" + } ] + } }, { "val" : "VHOG:0000318" }, { @@ -23542,7 +26711,13 @@ }, { "val" : "ZFA:0000101" }, { - "val" : "neuronames:288" + "val" : "neuronames:288", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1503" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -23636,9 +26811,24 @@ }, { "val" : "TAO:0000545" }, { - "val" : "UMLS:C0025148" - }, { - "val" : "UMLS:C1269575" + "val" : "UMLS:C0025148", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:957" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Medulla_Oblongata" + } ] + } + }, { + "val" : "UMLS:C1269575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:957" + } ] + } }, { "val" : "VHOG:0000181" }, { @@ -23648,7 +26838,13 @@ }, { "val" : "ZFA:0000545" }, { - "val" : "neuronames:698" + "val" : "neuronames:698", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:957" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -23725,7 +26921,16 @@ }, { "val" : "TAO:0000252" }, { - "val" : "UMLS:C0152405" + "val" : "UMLS:C0152405", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1684" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Tract" + } ] + } }, { "val" : "VHOG:0001164" }, { @@ -23735,7 +26940,13 @@ }, { "val" : "ZFA:0000252" }, { - "val" : "neuronames:460" + "val" : "neuronames:460", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1684" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -23818,13 +27029,25 @@ }, { "val" : "MAT:0000452" }, { - "val" : "MESH:D013681" + "val" : "MESH:D013681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "SCTID:362392007" }, { "val" : "TAO:0000160" }, { - "val" : "UMLS:C0039441" + "val" : "UMLS:C0039441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1200" + } ] + } }, { "val" : "VHOG:0001367" }, { @@ -23834,7 +27057,13 @@ }, { "val" : "ZFA:0000160" }, { - "val" : "neuronames:491" + "val" : "neuronames:491", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1200" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -23895,7 +27124,13 @@ }, { "val" : "NCIT:C13356" }, { - "val" : "UMLS:C0032105" + "val" : "UMLS:C0032105", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Plasma" + } ] + } }, { "val" : "Wikipedia:Blood_plasma" } ], @@ -23937,7 +27172,13 @@ }, { "val" : "TAO:0005315" }, { - "val" : "UMLS:C0042520" + "val" : "UMLS:C0042520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venule" + } ] + } }, { "val" : "VHOG:0001765" }, { @@ -23991,7 +27232,13 @@ }, { "val" : "TAO:0002138" }, { - "val" : "UMLS:C0003847" + "val" : "UMLS:C0003847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Arteriole" + } ] + } }, { "val" : "VHOG:0001763" }, { @@ -24074,7 +27321,13 @@ }, { "val" : "TAO:0002137" }, { - "val" : "UMLS:C0005847" + "val" : "UMLS:C0005847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel" + } ] + } }, { "val" : "VHOG:0001250" }, { @@ -24140,7 +27393,13 @@ }, { "val" : "TAO:0005250" }, { - "val" : "UMLS:C0935624" + "val" : "UMLS:C0935624", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary" + } ] + } }, { "val" : "VHOG:0001253" }, { @@ -24210,7 +27469,13 @@ }, { "val" : "TAO:0002186" }, { - "val" : "UMLS:C0014259" + "val" : "UMLS:C0014259", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Corneal_Endothelium" + } ] + } }, { "val" : "Wikipedia:Corneal_endothelium" }, { @@ -24255,7 +27520,13 @@ }, { "val" : "SCTID:27168002" }, { - "val" : "UMLS:C0014257" + "val" : "UMLS:C0014257", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endothelium" + } ] + } }, { "val" : "galen:Endothelium" } ], @@ -24318,7 +27589,13 @@ }, { "val" : "EHDAA2_RETIRED:0004658" }, { - "val" : "EMAPA:37596" + "val" : "EMAPA:37596", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67242" }, { @@ -24330,7 +27607,13 @@ }, { "val" : "TAO:0002197" }, { - "val" : "UMLS:C0018220" + "val" : "UMLS:C0018220", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gray_Matter" + } ] + } }, { "val" : "VHOG:0001768" }, { @@ -24405,9 +27688,24 @@ }, { "val" : "TAO:0000029" }, { - "val" : "UMLS:C0035507" - }, { - "val" : "UMLS:C1522180" + "val" : "UMLS:C0035507", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:942" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hind-Brain" + } ] + } + }, { + "val" : "UMLS:C1522180", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:942" + } ] + } }, { "val" : "VHOG:0000070" }, { @@ -24417,11 +27715,23 @@ }, { "val" : "ZFA:0000029" }, { - "val" : "neuronames:540" + "val" : "neuronames:540", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:942" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7762" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7762", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:8932866" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -24513,7 +27823,13 @@ }, { "val" : "EFO:0000461" }, { - "val" : "FBbt:00004208" + "val" : "FBbt:00004208", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69067" }, { @@ -24529,7 +27845,13 @@ }, { "val" : "TAO:0001105" }, { - "val" : "UMLS:C0013948" + "val" : "UMLS:C0013948", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Structure" + } ] + } }, { "val" : "VSAO:0000178" }, { @@ -24593,7 +27915,13 @@ }, { "val" : "SCTID:118760003" }, { - "val" : "UMLS:C0042779" + "val" : "UMLS:C0042779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Viscera" + } ] + } }, { "val" : "Wikipedia:Viscus" }, { @@ -24632,7 +27960,13 @@ }, { "val" : "EHDAA:5049" }, { - "val" : "EMAPA:37721" + "val" : "EMAPA:37721", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71221" }, { @@ -24640,7 +27974,13 @@ }, { "val" : "MAT:0000148" }, { - "val" : "MESH:D013131" + "val" : "MESH:D013131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000148" }, { @@ -24714,7 +28054,13 @@ }, { "val" : "TAO:0001115" }, { - "val" : "UMLS:C0460005" + "val" : "UMLS:C0460005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trunk" + } ] + } }, { "val" : "Wikipedia:Torso" }, { @@ -24766,7 +28112,13 @@ }, { "val" : "TAO:0001127" }, { - "val" : "UMLS:C0587900" + "val" : "UMLS:C0587900", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Visual_System" + } ] + } }, { "val" : "Wikipedia:Visual_system" }, { @@ -24966,7 +28318,13 @@ }, { "val" : "SCTID:278858007" }, { - "val" : "UMLS:C0026860" + "val" : "UMLS:C0026860", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Musculoskeletal_System" + } ] + } }, { "val" : "VHOG:0001275" }, { @@ -25092,7 +28450,13 @@ }, { "val" : "SCTID:243949006" }, { - "val" : "UMLS:C0230139" + "val" : "UMLS:C0230139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Thoracic_Cavity" + } ] + } }, { "val" : "Wikipedia:Thoracic_cavity" } ], @@ -25200,7 +28564,16 @@ }, { "val" : "TAO:0000075" }, { - "val" : "UMLS:C0037925" + "val" : "UMLS:C0037925", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1709" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Spinal_Cord" + } ] + } }, { "val" : "VHOG:0000601" }, { @@ -25210,7 +28583,13 @@ }, { "val" : "ZFA:0000075" }, { - "val" : "neuronames:22" + "val" : "neuronames:22", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1709" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -25311,7 +28690,16 @@ }, { "val" : "TAO:0002156" }, { - "val" : "UMLS:C0006121" + "val" : "UMLS:C0006121", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1565" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Brain_Stem" + } ] + } }, { "val" : "VHOG:0001457" }, { @@ -25319,7 +28707,13 @@ }, { "val" : "ZFA:0001707" }, { - "val" : "neuronames:236" + "val" : "neuronames:236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1565" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -25399,7 +28793,13 @@ }, { "val" : "TAO:0002143" }, { - "val" : "UMLS:C0682708" + "val" : "UMLS:C0682708", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:White_Matter" + } ] + } }, { "val" : "VHOG:0001764" }, { @@ -25477,7 +28877,13 @@ }, { "val" : "EHDAA2:0000267" }, { - "val" : "FBbt:00005060" + "val" : "FBbt:00005060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85006" }, { @@ -25489,7 +28895,13 @@ }, { "val" : "TAO:0001438" }, { - "val" : "UMLS:C0333343" + "val" : "UMLS:C0333343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cavity" + } ] + } }, { "val" : "galen:BodyCavity" } ], @@ -25553,7 +28965,13 @@ }, { "val" : "TAO:0000135" }, { - "val" : "UMLS:C0028439" + "val" : "UMLS:C0028439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochord" + } ] + } }, { "val" : "VHOG:0000199" }, { @@ -25649,7 +29067,13 @@ }, { "val" : "TAO:0000155" }, { - "val" : "UMLS:C0376449" + "val" : "UMLS:C0376449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somite" + } ] + } }, { "val" : "VHOG:0000191" }, { @@ -25661,7 +29085,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:17237766" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somite" @@ -25698,7 +29128,13 @@ }, { "val" : "NCIT:C12957" }, { - "val" : "UMLS:C1516995" + "val" : "UMLS:C1516995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_System" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" }, { @@ -25763,7 +29199,13 @@ }, { "val" : "SCTID:361462002" }, { - "val" : "UMLS:C0027789" + "val" : "UMLS:C0027789", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Crest" + } ] + } }, { "val" : "VHOG:0000057" }, { @@ -25835,7 +29277,13 @@ }, { "val" : "EV:0100004" }, { - "val" : "FBbt:00001057" + "val" : "FBbt:00001057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:87657" }, { @@ -25847,7 +29295,13 @@ }, { "val" : "TAO:0001120" }, { - "val" : "UMLS:C1518271" + "val" : "UMLS:C1518271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neuroectoderm" + } ] + } }, { "val" : "VHOG:0000150" }, { @@ -25905,7 +29359,13 @@ }, { "val" : "SCTID:115976003" }, { - "val" : "UMLS:C0015282" + "val" : "UMLS:C0015282", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" } ], @@ -25968,7 +29428,13 @@ }, { "val" : "TAO:0001641" }, { - "val" : "UMLS:C0009780" + "val" : "UMLS:C0009780", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Connective_Tissue" + } ] + } }, { "val" : "VSAO:0000017" }, { @@ -26036,7 +29502,13 @@ }, { "val" : "SCTID:91727004" }, { - "val" : "UMLS:C2328219" + "val" : "UMLS:C2328219", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle_Tissue" + } ] + } }, { "val" : "Wikipedia:Muscle_tissue" }, { @@ -26114,7 +29586,13 @@ }, { "val" : "TAO:0005023" }, { - "val" : "UMLS:C0018957" + "val" : "UMLS:C0018957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hematopoietic_System" + } ] + } }, { "val" : "VHOG:0001624" }, { @@ -26230,7 +29708,13 @@ }, { "val" : "EMAPA:18425" }, { - "val" : "FBbt:00100317" + "val" : "FBbt:00100317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7146" }, { @@ -26248,7 +29732,13 @@ }, { "val" : "SCTID:134358001" }, { - "val" : "UMLS:C1285092" + "val" : "UMLS:C1285092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gland" + } ] + } }, { "val" : "Wikipedia:Gland" }, { @@ -26384,7 +29874,13 @@ "xrefs" : [ { "val" : "BIRNLEX:1011" }, { - "val" : "EMAPA:37442" + "val" : "EMAPA:37442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67552" }, { @@ -26449,7 +29945,13 @@ }, { "val" : "SCTID:384763002" }, { - "val" : "UMLS:C0445620" + "val" : "UMLS:C0445620", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Brain_Part" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -26684,7 +30186,13 @@ }, { "val" : "TE:E5.11.2.0.0.0.4" }, { - "val" : "UMLS:C1511224" + "val" : "UMLS:C1511224", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Island" + } ] + } }, { "val" : "VHOG:0000085" }, { @@ -26844,7 +30352,13 @@ }, { "val" : "TAO:0001202" }, { - "val" : "UMLS:C0231109" + "val" : "UMLS:C0231109", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Cup" + } ] + } }, { "val" : "VHOG:0000167" }, { @@ -26893,7 +30407,13 @@ }, { "val" : "TAO:0000122" }, { - "val" : "UMLS:C1517770" + "val" : "UMLS:C1517770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lens_Placodes" + } ] + } }, { "val" : "VHOG:0000166" }, { @@ -26953,7 +30473,13 @@ }, { "val" : "TAO:0000132" }, { - "val" : "UMLS:C0920623" + "val" : "UMLS:C0920623", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Plate" + } ] + } }, { "val" : "VHOG:0000068" }, { @@ -27035,7 +30561,13 @@ }, { "val" : "TAO:0000255" }, { - "val" : "UMLS:C1284009" + "val" : "UMLS:C1284009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Paraxial_Mesoderm" + } ] + } }, { "val" : "VHOG:0000114" }, { @@ -27126,7 +30658,13 @@ }, { "val" : "TAO:0000121" }, { - "val" : "UMLS:C1517749" + "val" : "UMLS:C1517749", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lateral_Mesoderm" + } ] + } }, { "val" : "VHOG:0000118" }, { @@ -27171,7 +30709,13 @@ }, { "val" : "TAO:0000028" }, { - "val" : "UMLS:C1514450" + "val" : "UMLS:C1514450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium_of_the_Heart" + } ] + } }, { "val" : "XAO:0000336" }, { @@ -27221,7 +30765,13 @@ }, { "val" : "TAO:0001080" }, { - "val" : "UMLS:C0183176" + "val" : "UMLS:C0183176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclerotome" + } ] + } }, { "val" : "VHOG:0000680" }, { @@ -27275,7 +30825,13 @@ }, { "val" : "TAO:0000137" }, { - "val" : "UMLS:C0231107" + "val" : "UMLS:C0231107", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Stalk" + } ] + } }, { "val" : "VHOG:0000223" }, { @@ -27443,7 +30999,13 @@ }, { "val" : "TAO:0000393" }, { - "val" : "UMLS:C0162415" + "val" : "UMLS:C0162415", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesenchyme" + } ] + } }, { "val" : "VHOG:0000170" }, { @@ -27582,7 +31144,13 @@ }, { "val" : "NCIT:C49334" }, { - "val" : "UMLS:C1706995" + "val" : "UMLS:C1706995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Brain_White_Matter" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -27690,7 +31258,13 @@ }, { "val" : "SCTID:91728009" }, { - "val" : "UMLS:C0027757" + "val" : "UMLS:C0027757", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_Tissue" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -27952,7 +31526,13 @@ }, { "val" : "NCIT:C34195" }, { - "val" : "UMLS:C1512940" + "val" : "UMLS:C1512940", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intraembryonic_Coelom" + } ] + } }, { "val" : "VHOG:0000316" }, { @@ -27985,7 +31565,13 @@ }, { "val" : "NCIT:C67387" }, { - "val" : "UMLS:C0927195" + "val" : "UMLS:C0927195", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stroma_Connective_Tissue" + } ] + } } ] } }, { @@ -28047,7 +31633,13 @@ }, { "val" : "TAO:0000046" }, { - "val" : "UMLS:C1518263" + "val" : "UMLS:C1518263", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Retina" + } ] + } }, { "val" : "VHOG:0000535" }, { @@ -28081,7 +31673,13 @@ }, { "val" : "EHDAA2:0003114" }, { - "val" : "FBbt:00007474" + "val" : "FBbt:00007474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -28486,7 +32084,13 @@ }, { "val" : "TAO:0000050" }, { - "val" : "UMLS:C0231106" + "val" : "UMLS:C0231106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Vesicle" + } ] + } }, { "val" : "VHOG:0000165" }, { @@ -28845,7 +32449,13 @@ }, { "val" : "TAO:0002157" }, { - "val" : "UMLS:C0011665" + "val" : "UMLS:C0011665", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Descemet_s_Membrane" + } ] + } }, { "val" : "Wikipedia:Descemet%27s_membrane" }, { @@ -28926,7 +32536,13 @@ }, { "val" : "TAO:0002155" }, { - "val" : "UMLS:C0229127" + "val" : "UMLS:C0229127", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bowman_s_Membrane" + } ] + } }, { "val" : "Wikipedia:Bowman%27s_membrane" }, { @@ -29017,7 +32633,13 @@ }, { "val" : "TAO:0000010" }, { - "val" : "UMLS:C0007226" + "val" : "UMLS:C0007226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiovascular_System" + } ] + } }, { "val" : "VHOG:0000302" }, { @@ -29143,7 +32765,13 @@ }, { "val" : "SCTID:362060003" }, { - "val" : "UMLS:C1267406" + "val" : "UMLS:C1267406", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venous_System" + } ] + } }, { "val" : "VHOG:0000277" } ], @@ -29175,7 +32803,13 @@ }, { "val" : "TAO:0005257" }, { - "val" : "UMLS:C1706972" + "val" : "UMLS:C1706972", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel_Endothelium" + } ] + } }, { "val" : "ZFA:0005257" } ], @@ -29213,7 +32847,13 @@ }, { "val" : "NCIT:C34131" }, { - "val" : "UMLS:C1516779" + "val" : "UMLS:C1516779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conceptus" + } ] + } }, { "val" : "Wikipedia:Conceptus" } ], @@ -29327,7 +32967,13 @@ }, { "val" : "BTO:0001403" }, { - "val" : "FBbt:00005317" + "val" : "FBbt:00005317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:293108" }, { @@ -29341,9 +32987,21 @@ }, { "val" : "NCIT:C34058" }, { - "val" : "UMLS:C0017199" - }, { - "val" : "UMLS:C1284022" + "val" : "UMLS:C0017199", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrula" + } ] + } + }, { + "val" : "UMLS:C1284022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trilaminar_Embryonic_Disc" + } ] + } }, { "val" : "Wikipedia:Gastrula" }, { @@ -29459,7 +33117,13 @@ }, { "val" : "TAO:0002171" }, { - "val" : "UMLS:C0014261" + "val" : "UMLS:C0014261", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_Endothelium" + } ] + } }, { "val" : "VHOG:0001217" }, { @@ -29568,7 +33232,13 @@ "val" : "joint" } ], "xrefs" : [ { - "val" : "FBbt:00005811" + "val" : "FBbt:00005811", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -29605,7 +33275,13 @@ "xrefs" : [ "FMA:71131" ] } ], "xrefs" : [ { - "val" : "FBbt:00100315" + "val" : "FBbt:00100315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:71131" } ], @@ -29658,7 +33334,13 @@ }, { "val" : "SCTID:361463007" }, { - "val" : "UMLS:C0814992" + "val" : "UMLS:C0814992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Groove" + } ] + } }, { "val" : "Wikipedia:Neural_groove" }, { @@ -29695,7 +33377,13 @@ }, { "val" : "SCTID:361461009" }, { - "val" : "UMLS:C0814993" + "val" : "UMLS:C0814993", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Fold" + } ] + } }, { "val" : "Wikipedia:Neural_fold" }, { @@ -29831,7 +33519,13 @@ }, { "val" : "CARO:0001000" }, { - "val" : "FBbt:00007060" + "val" : "FBbt:00007060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:83115" } ], @@ -29859,7 +33553,13 @@ "val" : "dorsal region organ" } ], "xrefs" : [ { - "val" : "EMAPA:37274" + "val" : "EMAPA:37274", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0001901" } ], @@ -29884,7 +33584,13 @@ "xrefs" : [ "MA:0000516" ] } ], "xrefs" : [ { - "val" : "EMAPA:37270" + "val" : "EMAPA:37270", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000516" } ], @@ -29909,7 +33615,13 @@ "xrefs" : [ "MA:0000557" ] } ], "xrefs" : [ { - "val" : "EMAPA:37273" + "val" : "EMAPA:37273", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000557" } ], @@ -29934,7 +33646,13 @@ "xrefs" : [ "MA:0000563" ] } ], "xrefs" : [ { - "val" : "EMAPA:37271" + "val" : "EMAPA:37271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000563" } ], @@ -30112,7 +33830,13 @@ "val" : "light-sensitive tissue" } ], "xrefs" : [ { - "val" : "FBbt:00004200" + "val" : "FBbt:00004200", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -30162,7 +33886,13 @@ }, { "val" : "EHDAA2:0003125" }, { - "val" : "FBbt:00007006" + "val" : "FBbt:00007006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:292313" }, { @@ -30495,13 +34225,25 @@ }, { "val" : "SCTID:68989006" }, { - "val" : "UMLS:C0004799" + "val" : "UMLS:C0004799", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Basement_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "http://palaeos.com/metazoa/porifera/homoscleromorpha.html" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "basement membrane of epithelium" @@ -30608,7 +34350,13 @@ }, { "val" : "SCTID:361725000" }, { - "val" : "UMLS:C0222645" + "val" : "UMLS:C0222645", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Axial_Skeleton" + } ] + } }, { "val" : "VSAO:0000056" }, { @@ -30707,7 +34455,13 @@ }, { "val" : "SCTID:362296008" }, { - "val" : "UMLS:C0027750" + "val" : "UMLS:C0027750", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Myelinated_Nerve_Fiber" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -30748,7 +34502,13 @@ }, { "val" : "SCTID:46920005" }, { - "val" : "UMLS:C0501409" + "val" : "UMLS:C0501409", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Unmyelinated_Nerve_Fiber" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -30959,7 +34719,13 @@ }, { "val" : "NCIT:C34231" }, { - "val" : "UMLS:C1518429" + "val" : "UMLS:C1518429", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Plate" + } ] + } }, { "val" : "VHOG:0001212" } ], @@ -31000,7 +34766,13 @@ }, { "val" : "NCIT:C34232" }, { - "val" : "UMLS:C1518430" + "val" : "UMLS:C1518430", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Process" + } ] + } }, { "val" : "VHOG:0001213" } ], @@ -31034,7 +34806,13 @@ "xrefs" : [ { "val" : "BTO:0002085" }, { - "val" : "EMAPA:37529" + "val" : "EMAPA:37529", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:58071" }, { @@ -31044,7 +34822,13 @@ }, { "val" : "SCTID:280540004" }, { - "val" : "UMLS:C0459556" + "val" : "UMLS:C0459556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Chamber_of_the_Eye" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -31089,7 +34873,13 @@ "xrefs" : [ { "val" : "BIRNLEX:20" }, { - "val" : "EMAPA:37441" + "val" : "EMAPA:37441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:280556" }, { @@ -31313,7 +35103,13 @@ }, { "val" : "SCTID:40118003" }, { - "val" : "UMLS:C0221909" + "val" : "UMLS:C0221909", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Squamous_epithelium" } ], @@ -31366,7 +35162,13 @@ }, { "val" : "NCIT:C34022" }, { - "val" : "UMLS:C1515977" + "val" : "UMLS:C1515977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Surface" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -31485,7 +35287,13 @@ }, { "val" : "SCTID:360394002" }, { - "val" : "UMLS:C1514442" + "val" : "UMLS:C1514442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordial_Gut" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -32108,7 +35916,13 @@ }, { "val" : "EHDAA2:0003170" }, { - "val" : "FBbt:00005426" + "val" : "FBbt:00005426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "Wikipedia:Anlage_(biology)" } ], @@ -32224,7 +36038,13 @@ }, { "val" : "NCIT:C33854" }, { - "val" : "UMLS:C0489903" + "val" : "UMLS:C0489903", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_System" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -32280,7 +36100,13 @@ }, { "val" : "SCTID:361355005" }, { - "val" : "UMLS:C0460004" + "val" : "UMLS:C0460004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Head_and_Neck" + } ] + } }, { "val" : "WikipediaCategory:Head_and_neck" }, { @@ -32584,7 +36410,13 @@ "xrefs" : [ { "val" : "CARO:0010000" }, { - "val" : "FBbt:00100313" + "val" : "FBbt:00100313", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -33086,7 +36918,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007330" + "val" : "FBbt:00007330", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67509" }, { @@ -33199,7 +37037,13 @@ "val" : "main body segment" } ], "xrefs" : [ { - "val" : "FBbt:00057001" + "val" : "FBbt:00057001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -33285,7 +37129,13 @@ }, { "val" : "NCIT:C32450" }, { - "val" : "UMLS:C1511770" + "val" : "UMLS:C1511770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Dense_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Dense_connective_tissue" } ], @@ -33322,7 +37172,13 @@ }, { "val" : "NCIT:C33007" }, { - "val" : "UMLS:C1253917" + "val" : "UMLS:C1253917", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Loose_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Loose_connective_tissue" } ], @@ -33413,7 +37269,13 @@ "xrefs" : [ "MP:0005194" ] } ], "xrefs" : [ { - "val" : "EMAPA:37417" + "val" : "EMAPA:37417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "SCTID:280656002" } ], @@ -33461,7 +37323,13 @@ "val" : "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "coelom" @@ -33525,7 +37393,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7955" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7955", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1177/0192623311409597" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "tunica fibrosa of eyeball" @@ -33759,7 +37633,13 @@ "xrefs" : [ { "val" : "AEO:0000093" }, { - "val" : "FBbt:00007278" + "val" : "FBbt:00007278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -33824,7 +37704,13 @@ "xrefs" : [ "MA:0002449" ] } ], "xrefs" : [ { - "val" : "EMAPA:37597" + "val" : "EMAPA:37597", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002449" } ], @@ -34223,7 +38109,13 @@ "xrefs" : [ { "val" : "CARO:0020000" }, { - "val" : "FBbt:00007276" + "val" : "FBbt:00007276", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -34458,7 +38350,13 @@ "comments" : [ "It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however, most visceral muscles in arthropods are actually striated." ], "synonyms" : [ { "pred" : "hasExactSynonym", - "val" : "visceral muscle" + "val" : "visceral muscle", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "BTO:0002780" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -36119,7 +40017,13 @@ "meta" : { "definition" : { "val" : "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -36135,7 +40039,13 @@ "meta" : { "definition" : { "val" : "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -36459,7 +40369,7 @@ } }, { "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym", - "lbl" : "has_narrow_synonym", + "lbl" : "has narrow synonym", "type" : "PROPERTY", "propertyType" : "ANNOTATION", "meta" : { @@ -36598,6 +40508,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000008", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000333" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000030", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000030", "pred" : "is_a", @@ -36606,6 +40520,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000030", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", "obj" : "http://purl.obolibrary.org/obo/CL_0000133" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000031", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000031", "pred" : "is_a", @@ -36614,22 +40532,18 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000031", "pred" : "http://purl.obolibrary.org/obo/RO_0002162", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_7742" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0011115" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", - "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0017145" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000037", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000037", "pred" : "is_a", @@ -36796,6 +40710,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000076", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000066" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000076", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000077", "pred" : "is_a", @@ -37156,6 +41074,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000219" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000333", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", @@ -37296,6 +41218,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000540", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0019226" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000541", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000541", "pred" : "is_a", @@ -37712,6 +41638,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000679", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0061535" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000680", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000680", "pred" : "is_a", @@ -38214,6 +42144,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0002672", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000048" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0002672", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0002672", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", @@ -38236,6 +42170,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0007004", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", @@ -38330,10 +42268,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0011026", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", @@ -38700,7 +42634,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0032991" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005581", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "pred" : "http://purl.obolibrary.org/obo/RO_0002160", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005587", @@ -39142,6 +43076,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008016", "pred" : "http://purl.obolibrary.org/obo/RO_0002211", "obj" : "http://purl.obolibrary.org/obo/GO_0060047" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0008150", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", + "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -40605,7 +44543,7 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0071953", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", - "obj" : "http://purl.obolibrary.org/obo/GO_0031012" + "obj" : "http://purl.obolibrary.org/obo/GO_0140149" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0071971", "pred" : "is_a", @@ -40926,6 +44864,14 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0140143", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/GO_0140139" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0140149", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/GO_0030312" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0140149", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", + "obj" : "http://purl.obolibrary.org/obo/GO_0140151" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0140151", "pred" : "is_a", @@ -41042,6 +44988,14 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_117571", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_117570" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_119089", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6231" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33317" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_131567", "pred" : "is_a", @@ -41066,10 +45020,22 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6236" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33154" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "pred" : "is_a", @@ -41102,6 +45068,10 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33213", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6072" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33317", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33213" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33511", "pred" : "is_a", @@ -41154,10 +45124,34 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_554915", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2759" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_55879", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_55885", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6243" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6072", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6231", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6236", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_119089" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6237", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_55885" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6243", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_55879" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_7711", "pred" : "is_a", @@ -41290,6 +45284,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0001579", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0001591", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0000052" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0001690", "pred" : "is_a", @@ -41370,6 +45368,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002226", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001873" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0002254", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001591" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002266", "pred" : "is_a", @@ -49522,6 +53524,13 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0001981" } ] + }, { + "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000076", + "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], + "restrictions" : [ { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002254" + } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000081", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -52210,6 +56219,13 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" } ] + }, { + "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", + "allValuesFromEdges" : [ { + "sub" : "http://purl.obolibrary.org/obo/GO_0005581", + "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062", "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], diff --git a/src/ontology/subsets/eye_upper_slim.obo b/src/ontology/subsets/eye_upper_slim.obo index 37ec70605..d48854275 100644 --- a/src/ontology/subsets/eye_upper_slim.obo +++ b/src/ontology/subsets/eye_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2025-12-17/subsets/eye_upper_slim.owl +data-version: cl/releases/2026-03-17/subsets/eye_upper_slim.owl idspace: dc http://purl.org/dc/elements/1.1/ idspace: foaf http://xmlns.com/foaf/0.1/ idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# @@ -7,7 +7,7 @@ idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: terms http://purl.org/dc/terms/ ontology: cl/subsets/eye_upper_slim -property_value: owl:versionInfo "2025-12-17" xsd:string +property_value: owl:versionInfo "2026-03-17" xsd:string [Term] id: BFO:0000002 @@ -120,6 +120,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009010 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000030" xsd:string {name="glioblast on CELLxGENE CellGuide"} @@ -136,6 +137,7 @@ synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 xref: ZFA:0009011 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002162 NCBITaxon:7742 ! in taxon Vertebrata property_value: skos:prefLabel "neuroblast (sensu Vertebrata)" xsd:string @@ -144,21 +146,18 @@ property_value: skos:prefLabel "neuroblast (sensu Vertebrata)" xsd:string id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] -comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset -synonym: "animal stem cell" EXACT [] +synonym: "animal stem cell" NARROW [] xref: CALOHA:TS-2086 xref: FMA:63368 xref: ZFA:0005957 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa relationship: RO:0002215 GO:0017145 ! capable of stem cell division property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000034" xsd:string {name="stem cell on CELLxGENE CellGuide"} @@ -185,6 +184,7 @@ xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 xref: ZFA:0009014 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell @@ -425,13 +425,18 @@ property_value: skos:prefLabel "columnar/cuboidal epithelial cell" xsd:string [Term] id: CL:0000076 name: squamous epithelial cell +def: "An epithelial cell that has a flattened morphology." [] subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: CALOHA:TS-1249 xref: ZFA:0009039 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell +intersection_of: CL:0000066 ! epithelial cell +intersection_of: RO:0000053 PATO:0002254 ! has characteristic flattened +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: skos:prefLabel "squamous epithelial cell" xsd:string +property_value: terms:date "2025-12-16T15:56:39Z" xsd:dateTime [Term] id: CL:0000077 @@ -755,6 +760,7 @@ name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset subset: general_cell_types_upper_slim +subset: human_reference_atlas subset: human_subset subset: mouse_subset synonym: "muscle fiber" EXACT [] @@ -772,6 +778,7 @@ is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell relationship: RO:0002202 CL:0000056 ! develops from myoblast property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI +property_value: RO:0002175 NCBITaxon:9606 property_value: skos:prefLabel "muscle cell" xsd:string [Term] @@ -1037,6 +1044,7 @@ subset: mouse_subset xref: FMA:86667 xref: ZFA:0007086 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell @@ -1252,6 +1260,7 @@ subset: mouse_subset xref: BTO:0003217 xref: FMA:83377 xref: ZFA:0009249 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell @@ -1653,6 +1662,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009291 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell @@ -1778,6 +1788,7 @@ intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0001791 ! has soma location inner nuclear layer of retina relationship: RO:0002100 UBERON:0001791 ! has soma location inner nuclear layer of retina property_value: RO:0002175 NCBITaxon:9606 +property_value: seeAlso https://celltype.info/project/544/dataset/1157 {name="reference transcriptomic data on Cell Annotation Platform"} property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000748" xsd:string {name="retinal bipolar neuron on CELLxGENE CellGuide"} property_value: terms:description "The retinal bipolar neuron is an integral part of the eye, specifically located within the retina. They are secondary neurons in the visual pathway and primarily serve to transmit information from photoreceptor cells, which respond to light, to retinal ganglion cells, which carry the signal to the brain. As such, these cells play a pivotal role in our ability to interpret and perceive visual information.\nThe structure of retinal bipolar neurons is unique and significant to their function. They are termed \"bipolar\" due to their morphology, having two poles: a single dendrite on one end and an axon on the other. The dendrite end connects to photoreceptor cells (rods or cones), while the axon end synapses with retinal ganglion cells. In the center of the dendrite and axon lies the cell body, which houses the cell's nucleus and other vital organelles.\nAt the functional level, retinal bipolar neurons can be categorized into ON and OFF types based on their response to light. 'ON' bipolar cells are depolarized (electrical potential across the cell membrane decreases) under light conditions, thereby increasing their rate of neurotransmitter release onto the downstream ganglion cells. In contrast, 'OFF' bipolar cells are hyperpolarized (electrical potential increases) in light conditions, decreasing their rate of neurotransmitter release. This dual system allows for a fine-tuned response and the ability to perceive differences in light intensity and contrast, thus creating a nuanced and detailed visual world.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" xsd:string {xref="DOI:10.1016/j.preteyeres.2008.03.003", xref="DOI:10.1016/j.ydbio.2021.09.005", xref="DOI:10.1017/S0952523810000209", xref="DOI:10.1038/nrn3783", xref="DOI:10.1126/science.201028"} @@ -2293,6 +2304,7 @@ subset: eye_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset +synonym: "RPE" EXACT OMO:0003000 [PMID:35835183] xref: BTO:0004910 xref: FMA:75802 is_a: CL:0000066 ! epithelial cell @@ -2317,6 +2329,7 @@ subset: human_subset subset: mouse_subset is_a: BFO:0000002 is_a: CL:0000048 ! multi fate stem cell +is_a: CL:0000255 ! eukaryotic cell relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell property_value: skos:prefLabel "retinal progenitor cell" xsd:string property_value: terms:contributor https://orcid.org/0000-0003-1980-3228 @@ -2345,6 +2358,7 @@ subset: human_subset subset: mouse_subset xref: ZFA:0007084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: BFO:0000002 +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell @@ -2476,7 +2490,6 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset is_a: BFO:0000002 -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002202 CL:0000034 ! develops from stem cell @@ -2642,6 +2655,7 @@ is_a: GO:0140096 ! catalytic activity, acting on a protein is_a: GO:0140101 ! catalytic activity, acting on a tRNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0000262 @@ -2980,6 +2994,7 @@ subset: goslim_yeast synonym: "molecular function" EXACT [] disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process +property_value: IAO:0000116 "This is the same as GO molecular function" xsd:string [Term] id: GO:0003824 @@ -3016,6 +3031,9 @@ synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 +union_of: GO:0032991 ! protein-containing complex +union_of: GO:0044423 ! virion component +union_of: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0008150 ! biological_process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI @@ -3064,7 +3082,8 @@ namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa +relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa +relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0005587 @@ -3906,6 +3925,7 @@ synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process +relationship: BFO:0000051 GO:0003674 ! has part molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI creation_date: 2012-09-19T15:05:24Z @@ -4458,10 +4478,10 @@ subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" -xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016746 @@ -4478,6 +4498,7 @@ xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurin xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" is_a: GO:0016740 ! transferase activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016755 @@ -4487,6 +4508,7 @@ def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) synonym: "transferase activity, transferring amino-acyl groups" EXACT [] xref: EC:2.3.2.- is_a: GO:0016746 ! acyltransferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0017145 @@ -4703,6 +4725,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] @@ -4711,6 +4734,7 @@ is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] @@ -4718,6 +4742,7 @@ id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:18391171] +subset: gocheck_do_not_annotate synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly @@ -4725,6 +4750,7 @@ is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI [Term] id: GO:0030054 @@ -5063,6 +5089,7 @@ is_a: GO:0005575 ! cellular_component disjoint_from: GO:0044423 ! virion component disjoint_from: GO:0110165 ! cellular anatomical structure relationship: BFO:0000051 PR:000000001 ! has part protein +property_value: IAO:0000116 "This is not covalently bonded, which conflicts with changes to the parent definition." xsd:string [Term] id: GO:0034101 @@ -5190,12 +5217,13 @@ def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which mel xref: Wikipedia:Melanosome is_a: GO:0048770 ! pigment granule relationship: BFO:0000050 CL:0000148 ! part of melanocyte +property_value: RO:0002161 NCBITaxon:6237 [Term] id: GO:0042592 name: homeostatic process namespace: biological_process -def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] +def: "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." [PMID:26265027] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse @@ -5206,6 +5234,7 @@ synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological_process +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31175" xsd:anyURI [Term] id: GO:0042644 @@ -5272,6 +5301,7 @@ id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon @@ -5284,6 +5314,7 @@ synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: BFO:0000050 CL:0000000 ! part of cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: skos:prefLabel "cell projection" xsd:string [Term] @@ -6435,11 +6466,12 @@ creation_date: 2010-10-04T01:51:47Z id: GO:0071953 name: elastic fiber namespace: cellular_component -def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620] +def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, PMID:12082143, PMID:16893474, PMID:20236620] synonym: "elastic fibre" EXACT [GOC:mah] synonym: "elastin fiber" EXACT [GOC:BHF] is_a: GO:0099512 ! supramolecular fiber -relationship: BFO:0000050 GO:0031012 ! part of extracellular matrix +relationship: BFO:0000050 GO:0140149 ! part of non-collagenous component of interstitial matrix +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31135" xsd:anyURI property_value: skos:prefLabel "elastic fiber" xsd:string creation_date: 2010-10-11T11:44:57Z @@ -6574,15 +6606,16 @@ def: "A collagen trimer that forms networks." [PMID:21421911] is_a: BFO:0000004 is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer -intersection_of: BFO:0000050 GO:0098645 ! part of collagen network -relationship: BFO:0000050 GO:0098645 ! part of collagen network +intersection_of: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens +relationship: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens [Term] id: GO:0098643 -name: fibrillar collagen +name: fibrillar collagen complex namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175] synonym: "banded collagen fibril" EXACT [] +synonym: "fibrillar collagen" EXACT [] is_a: GO:0098644 ! complex of collagen trimers relationship: BFO:0000050 GO:0140152 ! part of collagenous component of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI @@ -6603,10 +6636,12 @@ property_value: skos:prefLabel "complex of collagen trimers" xsd:string [Term] id: GO:0098645 -name: collagen network +name: complex of network-forming collagens namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] +synonym: "collagen network" EXACT [] is_a: GO:0098644 ! complex of collagen trimers +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30938" xsd:anyURI [Term] id: GO:0098793 @@ -6742,6 +6777,8 @@ subset: goslim_pir synonym: "cellular anatomical entity" EXACT [] is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure +property_value: IAO:0000116 "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." xsd:string +property_value: IAO:0000116 "Overlaps with some cellular components from GO" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28978" xsd:anyURI @@ -6871,6 +6908,17 @@ relationship: BFO:0000050 GO:0140139 ! part of solid phase of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29472" xsd:anyURI creation_date: 2025-03-20T11:47:59Z +[Term] +id: GO:0140149 +name: non-collagenous component of interstitial matrix +namespace: cellular_component +def: "The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin." [PMID:21123617, PMID:25701227, PMID:33605520, PMID:39223427] +is_a: GO:0030312 ! external encapsulating structure +relationship: BFO:0000050 GO:0140151 ! part of solid phase of interstitial matrix +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29491" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30146" xsd:anyURI +creation_date: 2025-03-20T13:08:49Z + [Term] id: GO:0140151 name: solid phase of interstitial matrix @@ -6896,7 +6944,7 @@ id: GO:0140154 name: chicken-wire-like collagen network namespace: cellular_component def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942] -is_a: GO:0098645 ! collagen network +is_a: GO:0098645 ! complex of network-forming collagens relationship: BFO:0000050 GO:0140143 ! part of collagenous component of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI @@ -7057,6 +7105,21 @@ xref: GC_ID:1 is_a: NCBITaxon:117570 ! Teleostomi property_value: skos:prefLabel "Euteleostomi" xsd:string +[Term] +id: NCBITaxon:119089 +name: Chromadorea +namespace: ncbi_taxonomy +synonym: "Adenophorea" RELATED synonym [] +xref: GC_ID:1 +is_a: NCBITaxon:6231 ! Nematoda + +[Term] +id: NCBITaxon:1206794 +name: Ecdysozoa +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:33317 ! Protostomia + [Term] id: NCBITaxon:131567 name: cellular organisms @@ -7149,6 +7212,20 @@ xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2759 ! Eukaryota +[Term] +id: NCBITaxon:2301116 +name: Rhabditina +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:6236 ! Rhabditida + +[Term] +id: NCBITaxon:2301119 +name: Rhabditomorpha +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:2301116 ! Rhabditina + [Term] id: NCBITaxon:2759 name: Eukaryota @@ -7165,6 +7242,22 @@ xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: skos:prefLabel "Eukaryota" xsd:string +[Term] +id: NCBITaxon:28009 +name: Choanoflagellata +namespace: ncbi_taxonomy +synonym: "Choanoflagellatea" RELATED synonym [] +synonym: "choanoflagellates" EXACT genbank_common_name [] +synonym: "choanoflagellates" RELATED blast_name [] +synonym: "Choanoflagellida" RELATED synonym [] +synonym: "Choanomonada" RELATED synonym [] +synonym: "Choanozoa" RELATED synonym [] +xref: GC_ID:1 +xref: PMID:27765632 +is_a: NCBITaxon:33154 ! Opisthokonta +disjoint_from: NCBITaxon:33208 ! Metazoa +disjoint_from: NCBITaxon:4751 ! Fungi + [Term] id: NCBITaxon:314146 name: Euarchontoglires @@ -7249,6 +7342,14 @@ xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa property_value: skos:prefLabel "Bilateria" xsd:string +[Term] +id: NCBITaxon:33317 +name: Protostomia +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:33213 ! Bilateria +disjoint_from: NCBITaxon:33511 ! Deuterostomia + [Term] id: NCBITaxon:33511 name: Deuterostomia @@ -7368,6 +7469,20 @@ xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota +[Term] +id: NCBITaxon:55879 +name: Rhabditoidea +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:2301119 ! Rhabditomorpha + +[Term] +id: NCBITaxon:55885 +name: Peloderinae +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:6243 ! Rhabditidae + [Term] id: NCBITaxon:6072 name: Eumetazoa @@ -7376,6 +7491,41 @@ xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: skos:prefLabel "Eumetazoa" xsd:string +[Term] +id: NCBITaxon:6231 +name: Nematoda +namespace: ncbi_taxonomy +synonym: "Nemata" RELATED synonym [] +synonym: "nematode" EXACT OMO:0003003 [] +synonym: "nematodes" EXACT genbank_common_name [] +synonym: "nematodes" RELATED blast_name [] +synonym: "roundworm" EXACT OMO:0003003 [] +synonym: "roundworms" EXACT OMO:0003003 [] +xref: GC_ID:1 +is_a: NCBITaxon:1206794 ! Ecdysozoa + +[Term] +id: NCBITaxon:6236 +name: Rhabditida +namespace: ncbi_taxonomy +synonym: "Strongylida" RELATED synonym [] +xref: GC_ID:1 +is_a: NCBITaxon:119089 ! Chromadorea + +[Term] +id: NCBITaxon:6237 +name: Caenorhabditis +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:55885 ! Peloderinae + +[Term] +id: NCBITaxon:6243 +name: Rhabditidae +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:55879 ! Rhabditoidea + [Term] id: NCBITaxon:7711 name: Chordata @@ -7706,6 +7856,14 @@ subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality +[Term] +id: PATO:0001591 +name: curvature +namespace: quality +def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] +subset: attribute_slim +is_a: PATO:0000052 ! shape + [Term] id: PATO:0001690 name: contractile @@ -7882,6 +8040,18 @@ is_a: PATO:0001873 ! cylindrical property_value: terms:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-07-13T04:22:30Z +[Term] +id: PATO:0002254 +name: flattened +namespace: quality +def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] +comment: Becoming flat but not necessarily completely flat. +subset: value_slim +synonym: "compressed" RELATED [] +is_a: PATO:0001591 ! curvature +property_value: terms:contributor https://orcid.org/0000-0002-2061-091X +creation_date: 2010-08-16T03:59:34Z + [Term] id: PATO:0002266 name: 3-D shape @@ -17948,7 +18118,7 @@ xref: NCIT:C32339 xref: NIF_Subcellular:sao7547390221 is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: RO:0002473 GO:0005581 ! composed primarily of collagen trimer -relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen +relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen complex property_value: seeAlso UBERON:0007377 property_value: skos:prefLabel "collection of collagen fibrils" xsd:string diff --git a/src/ontology/subsets/eye_upper_slim.owl b/src/ontology/subsets/eye_upper_slim.owl index 80d50f337..d9a4c8213 100644 --- a/src/ontology/subsets/eye_upper_slim.owl +++ b/src/ontology/subsets/eye_upper_slim.owl @@ -14,8 +14,8 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - - 2025-12-17 + + 2026-03-17 @@ -245,7 +245,6 @@ WHERE { An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has narrow synonym - has_narrow_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/19 @@ -2856,6 +2855,7 @@ Each of these 3 primitives can be composed to yield a cross-product of different + @@ -2912,6 +2912,7 @@ When glioblast multiplication is dysregulated, it can lead to harmful manifestat + @@ -2960,14 +2961,7 @@ When glioblast multiplication is dysregulated, it can lead to harmful manifestat - - - - - - - @@ -2984,13 +2978,12 @@ Stem cells have numerous potential applications in medicine, including the treat CALOHA:TS-2086 FMA:63368 ZFA:0005957 - animal stem cell + animal stem cell - This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. stem cell https://cellxgene.cziscience.com/cellguide/CL_0000034 stem cell @@ -3097,6 +3090,7 @@ Stem cells have numerous potential applications in medicine, including the treat + @@ -3886,7 +3880,26 @@ Blood vessel endothelial cells are sensitive to various stimuli, including shear + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -4817,6 +4830,7 @@ In addition to melanin production, melanocytes also engage in a variety of other A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -4830,6 +4844,7 @@ In addition to melanin production, melanocytes also engage in a variety of other + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -5622,6 +5637,7 @@ The spatial distribution of these cell types throughout the retina also contribu + @@ -6215,6 +6231,7 @@ Functionally, smooth muscle myoblasts and the mature muscle cells they generate + @@ -7753,6 +7770,7 @@ Moreover, Mueller cells are also responsible for maintaining the structural inte + @@ -8183,6 +8201,7 @@ At the functional level, retinal bipolar neurons can be categorized into ON and retinal bipolar neuron + https://cellxgene.cziscience.com/cellguide/CL_0000748 @@ -8234,6 +8253,12 @@ At the functional level, retinal bipolar neurons can be categorized into ON and + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -9779,6 +9804,7 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest 2011-03-06T03:37:09Z BTO:0004910 FMA:75802 + RPE @@ -9807,6 +9833,13 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest DOI:10.3389/fphar.2021.727870/full https://www.sciencedirect.com/topics/chemistry/retinal-pigment + + + + RPE + PMID:35835183 + + @@ -9821,6 +9854,7 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest + @@ -9901,6 +9935,7 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest + @@ -10169,7 +10204,7 @@ In the field of regenerative medicine, mesenchymal cells, particularly mesenchym - + Any photoreceptor cell that is part of some camera-type eye. camera type eye photoreceptor cell @@ -10177,14 +10212,14 @@ In the field of regenerative medicine, mesenchymal cells, particularly mesenchym camera-type eye photoreceptor cell camera-type eye photoreceptor cell - + - + https://github.com/obophenotype/cell-ontology/issues/2245 @@ -10273,7 +10308,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -10775,6 +10809,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. https://github.com/geneontology/go-ontology/issues/22192 https://github.com/geneontology/go-ontology/issues/25493 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.12 MetaCyc:PEPTIDYLTRANSFERASE-RXN Reactome:R-HSA-156912 @@ -11720,6 +11755,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. + This is the same as GO molecular function molecular function molecular_function GO:0003674 @@ -11782,6 +11818,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + @@ -11901,10 +11946,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component @@ -14010,6 +14061,12 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. https://github.com/geneontology/go-ontology/issues/24968 2012-09-19T15:05:24Z @@ -14241,6 +14298,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. @@ -14289,6 +14370,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + @@ -14359,6 +14450,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + @@ -14429,6 +14530,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + @@ -14465,6 +14576,70 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. @@ -15349,10 +15524,10 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + https://github.com/geneontology/go-ontology/issues/30193 EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 - Reactome:R-HSA-5333607 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function @@ -15387,12 +15562,6 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 - - - - Reactome:R-HSA-5333607 - GSSeH combines with bGalNAc derivative to form GSSebGalNac - @@ -15414,6 +15583,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 @@ -15464,6 +15634,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function @@ -16084,12 +16255,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 https://github.com/geneontology/go-ontology/issues/26279 cell projection organisation biological_process cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 + cell projection organization @@ -16139,10 +16312,12 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 formation of a cell surface projection biological_process cell projection biogenesis GO:0030031 + cell projection assembly @@ -17045,6 +17220,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + This is not covalently bonded, which conflicts with changes to the parent definition. macromolecular complex macromolecule complex protein containing complex @@ -17476,13 +17652,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. + Wikipedia:Melanosome cellular_component GO:0042470 @@ -17502,7 +17695,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - Any biological process involved in the maintenance of an internal steady state. + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + https://github.com/geneontology/go-ontology/issues/31175 homeostasis activation of homeostatic process inhibition of homeostatic process @@ -17519,9 +17713,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - Any biological process involved in the maintenance of an internal steady state. - GOC:jl - ISBN:0395825172 + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + PMID:26265027 @@ -17629,6 +17822,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + @@ -17737,11 +17940,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 cell process cellular process cellular projection cellular_component GO:0042995 + @@ -20851,10 +21056,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. + https://github.com/geneontology/go-ontology/issues/31135 2010-10-11T11:44:57Z elastic fibre elastin fiber @@ -20868,7 +21074,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. GOC:BHF - GOC:mah + PMID:12082143 + PMID:16893474 PMID:20236620 @@ -21320,9 +21527,10 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://github.com/geneontology/go-ontology/issues/29474 https://github.com/geneontology/go-ontology/issues/30146 banded collagen fibril + fibrillar collagen cellular_component GO:0098643 - fibrillar collagen + fibrillar collagen complex fibrillar collagen @@ -21387,9 +21595,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A supramolecular complex that consists of collagen triple helices associated to form a network. + https://github.com/geneontology/go-ontology/issues/30938 + collagen network cellular_component GO:0098645 - collagen network + complex of network-forming collagens @@ -21805,6 +22015,9 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes. + Overlaps with some cellular components from GO https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 https://github.com/geneontology/go-ontology/issues/28978 @@ -22151,6 +22364,36 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin. + https://github.com/geneontology/go-ontology/issues/29491 + https://github.com/geneontology/go-ontology/issues/30146 + 2025-03-20T13:08:49Z + cellular_component + GO:0140149 + non-collagenous component of interstitial matrix + + + + + The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin. + PMID:21123617 + PMID:25701227 + PMID:33605520 + PMID:39223427 + + + + @@ -22648,6 +22891,37 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + GC_ID:1 + ncbi_taxonomy + Adenophorea + NCBITaxon:119089 + Chromadorea + + + + + Adenophorea + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:1206794 + Ecdysozoa + + + + @@ -22872,6 +23146,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:2301116 + Rhabditina + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:2301119 + Rhabditomorpha + + + + @@ -22929,6 +23227,63 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + GC_ID:1 + PMID:27765632 + choanoflagellates + ncbi_taxonomy + Choanoflagellatea + Choanoflagellida + Choanomonada + Choanozoa + choanoflagellates + NCBITaxon:28009 + Choanoflagellata + + + + + choanoflagellates + + + + + + Choanoflagellatea + + + + + + Choanoflagellida + + + + + + Choanomonada + + + + + + Choanozoa + + + + + + choanoflagellates + + + + + @@ -23119,6 +23474,19 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:33317 + Protostomia + + + + @@ -23375,6 +23743,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:55879 + Rhabditoidea + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:55885 + Peloderinae + + + + @@ -23388,6 +23780,103 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + GC_ID:1 + nematode + nematodes + roundworm + roundworms + ncbi_taxonomy + Nemata + nematodes + NCBITaxon:6231 + Nematoda + + + + + nematode + + + + + + nematodes + + + + + + roundworm + + + + + + roundworms + + + + + + Nemata + + + + + + nematodes + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + Strongylida + NCBITaxon:6236 + Rhabditida + + + + + Strongylida + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:6237 + Caenorhabditis + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:6243 + Rhabditidae + + + + @@ -24142,6 +24631,25 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + quality + PATO:0001591 + + curvature + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + WordNet:WordNet + + + + @@ -24526,6 +25034,29 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + + 2010-08-16T03:59:34Z + quality + compressed + PATO:0002254 + + Becoming flat but not necessarily completely flat. + flattened + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + PATOC:CVS + + + + @@ -25988,7 +26519,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -26026,14 +26557,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou camera-type eye camera-type eye - + - + definitional @@ -27381,7 +27912,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube) EHDAA2:0001968 @@ -27404,7 +27935,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou external ectoderm http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png - + @@ -27417,7 +27948,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 @@ -27495,7 +28026,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -27506,14 +28037,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou membrane organ membrane organ - + - + FMA-def @@ -28282,7 +28813,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -28324,14 +28855,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou gastrula stage gastrula stage - + - + BILS @@ -28913,15 +29444,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - - + + A fluid that is composed of blood plasma and erythrocytes. @@ -28960,34 +29491,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou blood blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -30820,7 +31351,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. AAO:0000137 BILA:0000036 @@ -30855,14 +31386,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -30902,7 +31433,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. AAO:0000139 BILA:0000038 @@ -30937,14 +31468,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -30985,7 +31516,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The middle germ layer of the embryo, between the endoderm and ectoderm. AAO:0000304 @@ -31025,14 +31556,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + - + Bgee:AN @@ -31215,7 +31746,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -31279,14 +31810,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou cranial nerve II cranial nerve II - + - + EHDAA2 @@ -31396,7 +31927,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -31461,14 +31992,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb - + - + MA @@ -31510,7 +32041,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -31535,7 +32066,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. requires review for applicability to invertebrate structures, e.g. synganglion @@ -31595,11 +32126,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://cdn.humanatlas.io/digital-objects/ref-organ/brain-female/v1.4/assets/3d-allen-f-brain.glb https://cdn.humanatlas.io/digital-objects/ref-organ/brain-male/v1.4/assets/3d-allen-m-brain.glb - + - + @@ -31612,13 +32143,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + FMA - + Bgee:AN @@ -31870,9 +32401,9 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - + + + @@ -31897,7 +32428,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -31951,44 +32482,44 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou cornea http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + - + MA - + MA - + FMA-isa - + definitional @@ -32165,10 +32696,10 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - - + + + + The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. @@ -32216,44 +32747,44 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou retina http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png - + - + - + - + - + FMA - + FMA - + FMA - + EHDAA2 @@ -32308,8 +32839,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -32341,24 +32872,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eye eye - + - + - + PMID:21062451 - + PMID:21062451 @@ -32758,7 +33289,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -32809,14 +33340,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -32876,7 +33407,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. @@ -32921,7 +33452,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou central nervous system central nervous system - + @@ -32935,7 +33466,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Bgee:AN @@ -33667,7 +34198,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -33692,14 +34223,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -34080,7 +34611,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A tube extending from the mouth to the anus. @@ -34118,14 +34649,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou digestive tract digestive tract - + - + NCBIBook:NBK10107 @@ -34186,7 +34717,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. BTO:0000654 @@ -34209,7 +34740,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ciliary muscle http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png - + @@ -34228,7 +34759,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + FMA @@ -34517,7 +35048,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -34562,14 +35093,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eyelid https://upload.wikimedia.org/wikipedia/commons/8/84/Eye_makeup.jpg - + - + multiple @@ -34828,7 +35359,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -34867,14 +35398,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou iris iris - + - + XAO @@ -34928,7 +35459,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -34977,14 +35508,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou corneal epithelium http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + ISBN:0781772214 @@ -35072,15 +35603,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + - + @@ -35121,34 +35652,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou sclera http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + FMA - + ZFA - + ISBN:0781772214 @@ -35191,7 +35722,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -35229,14 +35760,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ciliary body http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + ISBN:0781772214 @@ -35274,14 +35805,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + @@ -35342,24 +35873,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou optic choroid http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + MA - + Wikipedia @@ -35542,15 +36073,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - - - + + + A double layer covering the ciliary body that produces aqueous humor. BTO:0001770 @@ -35570,15 +36101,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ciliary epithelium ciliary epithelium - + - + - + @@ -35591,19 +36122,19 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + MA - + MP - + Wikipedia @@ -35719,7 +36250,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -35776,14 +36307,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou pigmented layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + - + Wikipedia @@ -35859,7 +36390,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -35890,14 +36421,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou photoreceptor layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + - + ZFA @@ -36388,7 +36919,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -36443,7 +36974,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ganglionic layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + @@ -36456,7 +36987,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + FMA @@ -36510,7 +37041,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -36563,14 +37094,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou nerve fiber layer of retina - + - + FMA @@ -37260,7 +37791,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -37292,14 +37823,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou anterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png - + - + cjm @@ -37342,7 +37873,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -37372,14 +37903,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou posterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + cjm @@ -37416,9 +37947,9 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - + + + @@ -37465,15 +37996,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou conjunctiva http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png - + - + - + @@ -37486,19 +38017,19 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + cjm - + MA - + ISBN:0781772214 @@ -37562,7 +38093,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The most anterior region of the brain including both the telencephalon and diencephalon. @@ -37604,14 +38135,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou forebrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -37651,14 +38182,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. developmental relationships need revised @@ -37704,24 +38235,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG - + - + - + definitional - + Bgee:AN @@ -37773,14 +38304,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + The division of the forebrain that develops from the foremost primary cerebral vesicle. DiE @@ -37837,24 +38368,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou diencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + - + definitional - + definitional @@ -38204,7 +38735,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. MTg @@ -38244,14 +38775,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain tegmentum http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png - + - + ZFA @@ -38578,8 +39109,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -38592,7 +39123,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -38646,34 +39177,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -39079,7 +39610,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. @@ -39122,14 +39653,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou hindbrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + Bgee:AN @@ -39771,7 +40302,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Vasculature that is part of the eye region. FMA:74743 @@ -39793,14 +40324,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://cdn.humanatlas.io/digital-objects/ref-organ/blood-vasculature-female/v1.3/assets/3d-vh-f-blood-vasculature.glb https://cdn.humanatlas.io/digital-objects/ref-organ/blood-vasculature-male/v1.3/assets/3d-vh-m-blood-vasculature.glb - + - + ISBN:0781772214 @@ -40077,15 +40608,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - - + + Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). TODO - add superclass to unify with VNC? @@ -40141,34 +40672,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://cdn.humanatlas.io/digital-objects/ref-organ/spinal-cord-female/v1.1/assets/3d-vh-f-spinal-cord.glb https://cdn.humanatlas.io/digital-objects/ref-organ/spinal-cord-male/v1.1/assets/3d-vh-m-spinal-cord.glb - + - + - + - + ZFA - + definitional - + definitional @@ -40499,7 +41030,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -40535,14 +41066,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou coelemic cavity lumen coelemic cavity lumen - + - + definitional @@ -40638,8 +41169,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -40689,11 +41220,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -40712,13 +41243,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA - + EHDAA2 @@ -40759,7 +41290,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. mesodermal cluster @@ -40797,7 +41328,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -40810,7 +41341,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA @@ -40929,16 +41460,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - + + + - + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. AAO:0010578 BTO:0001764 @@ -40971,45 +41502,45 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + BTO - + PMID:11523831 - + PMID:11523831 @@ -41370,8 +41901,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + Anatomical system that is involved in the production of hematopoietic cells. @@ -41412,24 +41943,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou hematopoietic system hematopoietic system - + - + - + FMA - + definitional @@ -41460,14 +41991,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - - + + @@ -41493,11 +42024,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou iris epithelium iris epithelium - + - + @@ -41510,13 +42041,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + MA - + MP @@ -41751,7 +42282,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. Do not merge with neurogenic placode ectodermal placode @@ -41768,7 +42299,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou cranial placode cranial placode - + @@ -41781,7 +42312,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + PMID:11523831 PMID:22512454 @@ -41981,7 +42512,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -41994,7 +42525,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. consider adding class for organizer. Consider adding separate class for isthmus as a structure AAO:0011064 @@ -42023,24 +42554,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain-hindbrain boundary midbrain-hindbrain boundary - + - + - + ZFA - + ZFA @@ -42153,7 +42684,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -42172,7 +42703,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. AAO:0011086 EFO:0001982 @@ -42195,14 +42726,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presomitic mesoderm presomitic mesoderm - + - + Bgee:AN @@ -42371,7 +42902,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -42407,7 +42938,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eye primordium eye primordium - + @@ -42420,7 +42951,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + PMID:16496288 XAO @@ -42470,8 +43001,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -42499,24 +43030,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou optic cup optic cup - + - + - + ZFA - + ZFA @@ -42572,7 +43103,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -42610,7 +43141,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou lens placode http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png - + @@ -42623,7 +43154,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA @@ -42662,8 +43193,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. AAO:0011072 BTO:0001765 @@ -42692,24 +43223,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + Wikipedia - + Bgee:AN @@ -42791,7 +43322,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. AAO:0010568 EFO:0003515 @@ -42817,7 +43348,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -42830,7 +43361,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Bgee:AN @@ -42907,7 +43438,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -42946,7 +43477,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -42959,7 +43490,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 VHOG @@ -43010,15 +43541,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. AAO:0011044 @@ -43035,15 +43566,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou heart primordium heart primordium - + - + - + @@ -43056,19 +43587,19 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA - + ZFA - + XAO @@ -43097,8 +43628,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. AAO:0010571 AEO:0000212 @@ -43122,11 +43653,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -43145,13 +43676,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + VHOG:0000680 - + ZFA @@ -43465,7 +43996,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Mesenchyme that is part of a developing camera-type eye. TODO - change mesenchyme relationships to precursor_of EHDAA2:0000485 @@ -43477,14 +44008,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eye mesenchyme eye mesenchyme - + - + EHDAA2 @@ -44293,7 +44824,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults EHDAA:251 @@ -44308,14 +44839,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou intraembryonic coelom intraembryonic coelom - + - + Wikipedia @@ -44381,7 +44912,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -44399,7 +44930,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The part of the retina that contains neurons and photoreceptor cells[GO]. AAO:0011095 @@ -44430,14 +44961,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou retinal neural layer retinal neural layer - + - + Bgee:AN @@ -44737,7 +45268,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. consider merging with 'ventricular zone'; note that the MA class probably does not belong here, as this is an embryonic structure ependymal layer @@ -44754,7 +45285,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou neural tube ventricular layer neural tube ventricular layer - + @@ -44767,7 +45298,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + NCBIBook:NBK10047 @@ -45176,9 +45707,9 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - + + + @@ -45210,34 +45741,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou optic vesicle http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png - + - + - + - + ZFA - + GO-def - + ZFA @@ -45333,8 +45864,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. XAO:0004185 first heart field @@ -45346,24 +45877,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou primary heart field primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -45416,7 +45947,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + An epithelial tube that will give rise to the mature heart. AAO:0010411 EFO:0003526 @@ -45435,14 +45966,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou heart tube heart tube - + - + ZFA-modified @@ -45509,12 +46040,12 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + @@ -45530,14 +46061,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eye muscle eye muscle - + - + MA @@ -45720,7 +46251,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. @@ -45750,14 +46281,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Descemet's membrane https://github.com/obophenotype/uberon/issues/15 - + - + Cline et al @@ -46597,7 +47128,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. AAO:0011129 TAO:0001890 @@ -46611,14 +47142,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou skeletal element skeletal element - + - + VSAO @@ -46646,7 +47177,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -46679,14 +47210,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou articular system articular system - + - + FMA @@ -47523,7 +48054,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. EFO:0003492 EHDAA2:0000732 @@ -47544,14 +48075,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou head mesenchyme head mesenchyme - + - + EHDAA2 @@ -47609,7 +48140,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -47625,14 +48156,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou trunk mesenchyme trunk mesenchyme - + - + EHDAA2 @@ -47655,7 +48186,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. BTO:0000758 CALOHA:TS-0607 @@ -47675,14 +48206,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou myelencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -48150,7 +48681,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. TAO:0002188 ZFA:0001688 @@ -48158,7 +48689,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou corneal primordium corneal primordium - + @@ -48177,7 +48708,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA @@ -48200,7 +48731,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. EHDAA2:0001512 EHDAA:424 @@ -48218,14 +48749,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou primitive heart tube primitive heart tube - + - + ZFA @@ -48408,7 +48939,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -48418,7 +48949,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou developing mesenchymal condensation developing mesenchymal condensation - + @@ -48437,7 +48968,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + AEO-modified-relation @@ -48495,8 +49026,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -48512,11 +49043,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou UBERON:0005908 conjunctival sac - + - + @@ -48529,13 +49060,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + FMA - + HPO:pr @@ -48820,7 +49351,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -48843,14 +49374,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou future diencephalon future diencephalon - + - + EHDAA2 @@ -49026,7 +49557,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -49050,14 +49581,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou future spinal cord future spinal cord - + - + EHDAA2 @@ -49094,7 +49625,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB EHDAA2:0001278 @@ -49108,7 +49639,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou notochordal plate notochordal plate - + @@ -49121,7 +49652,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 @@ -49150,7 +49681,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -49167,14 +49698,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou notochordal process notochordal process - + - + EHDAA2 @@ -50199,8 +50730,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -50226,24 +50757,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presumptive hindbrain presumptive hindbrain - + - + - + XAO-abduced - + cjm @@ -50294,7 +50825,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -50313,14 +50844,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presumptive midbrain hindbrain boundary presumptive midbrain hindbrain boundary - + - + ZFA @@ -50467,7 +50998,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -50493,7 +51024,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presumptive paraxial mesoderm presumptive paraxial mesoderm - + @@ -50509,7 +51040,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + https://github.com/obophenotype/uberon/issues/1277 @@ -50583,12 +51114,12 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + A neural decussation that is part of a diencephalon. FMA:62446 diencephalon decussation @@ -50596,7 +51127,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou decussation of diencephalon decussation of diencephalon - + @@ -50609,7 +51140,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Obol @@ -50685,7 +51216,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -50693,7 +51224,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou dense mesenchyme tissue dense mesenchyme tissue - + @@ -50706,7 +51237,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + AEO @@ -50772,7 +51303,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -50792,14 +51323,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou layer of synovial tissue layer of synovial tissue - + - + BTO @@ -51107,7 +51638,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + An axon tract that is part of a brain. the NIFSTD class 'nerve tract' is classified under 'regional part of brain', so it may seem like it belongs here, but actually includes spinal cord tracts FMA:83848 @@ -51117,14 +51648,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou tract of brain tract of brain - + - + cjm @@ -51259,7 +51790,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -51276,14 +51807,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou vascular system vascular system - + - + MA @@ -51407,7 +51938,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -51423,14 +51954,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou entire embryonic mesenchyme entire embryonic mesenchyme - + - + EHDAA2 @@ -51527,7 +52058,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -51543,14 +52074,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain hindbrain boundary neural plate midbrain hindbrain boundary neural plate - + - + ZFA @@ -51584,14 +52115,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + @@ -51616,24 +52147,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presumptive midbrain presumptive midbrain - + - + - + ZFA - + ZFA @@ -51679,7 +52210,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme @@ -51687,14 +52218,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou trunk paraxial mesoderm trunk paraxial mesoderm - + - + EHDAA2 @@ -51789,7 +52320,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -51799,14 +52330,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou anterior lateral plate mesoderm anterior lateral plate mesoderm - + - + ZFA @@ -51862,14 +52393,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2:0001315 EHDAA:1122 UBERON:0009920 optic neural crest optic neural crest - + @@ -51882,7 +52413,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 @@ -52022,7 +52553,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -52045,14 +52576,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eyeball of camera-type eye eyeball of camera-type eye - + - + FMA @@ -52093,8 +52624,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. DHBA:12322 EFO:0003567 @@ -52108,11 +52639,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain basal plate midbrain basal plate - + - + @@ -52125,13 +52656,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 - + ZFA @@ -52159,7 +52690,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Portion of neural tube that gives rise to the midbrain. we follow ZFA in temporally dividing midbrain NT from presumptive midbrain, but in future this may be collapsed TAO:0007039 @@ -52168,14 +52699,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain neural tube midbrain neural tube - + - + ZFA @@ -52203,7 +52734,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Developing anatomical structure that develops into the eyeball and associated structures. TAO:0002201 ZFA:0001678 @@ -52212,14 +52743,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou immature eye immature eye - + - + definitional @@ -52484,7 +53015,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -52494,14 +53025,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou microcirculatory vessel microcirculatory vessel - + - + ZFA @@ -52526,8 +53057,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. FMA:23879 SCTID:129140006 @@ -52539,11 +53070,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou subdivision of skeleton subdivision of skeleton - + - + @@ -52556,13 +53087,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + UBERONREF:0000003 - + VSAO @@ -52656,7 +53187,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -52667,7 +53198,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton postcranial axial skeletal system - + @@ -52680,7 +53211,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + cjm @@ -52800,7 +53331,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + AAO:0010038 EMAPA:18808 FMA:49150 @@ -52810,14 +53341,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou intra-ocular muscle intra-ocular muscle - + - + EMAPA @@ -53203,7 +53734,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -53251,7 +53782,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou anterior uvea anterior uvea - + @@ -53264,7 +53795,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + MP @@ -54143,7 +54674,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -54166,7 +54697,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou entire extraembryonic component entire extraembryonic component - + @@ -54179,7 +54710,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + AEO @@ -55055,14 +55586,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + - + @@ -55256,14 +55787,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + definitional - + @@ -55461,6 +55992,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -55555,6 +56114,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -55569,6 +56156,40 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -55701,6 +56322,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + @@ -55883,6 +56528,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -55897,6 +56570,62 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/src/ontology/subsets/eye_upper_slim.tsv b/src/ontology/subsets/eye_upper_slim.tsv index 036f1ccea..a00cb6c4d 100644 --- a/src/ontology/subsets/eye_upper_slim.tsv +++ b/src/ontology/subsets/eye_upper_slim.tsv @@ -424,9 +424,9 @@ http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer -http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen +http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers -http://purl.obolibrary.org/obo/GO_0098645 collagen network +http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling @@ -449,6 +449,7 @@ http://purl.obolibrary.org/obo/GO_0140101 catalytic activity, acting on a tRNA http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis http://purl.obolibrary.org/obo/GO_0140139 solid phase of basement membrane http://purl.obolibrary.org/obo/GO_0140143 collagenous component of basement membrane +http://purl.obolibrary.org/obo/GO_0140149 non-collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0140151 solid phase of interstitial matrix http://purl.obolibrary.org/obo/GO_0140152 collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0140154 chicken-wire-like collagen network @@ -465,13 +466,18 @@ http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_10090 Mus musculus http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi +http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea +http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria +http://purl.obolibrary.org/obo/NCBITaxon_2301116 Rhabditina +http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota +http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda @@ -480,6 +486,7 @@ http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria +http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_34346 Schizosaccharomycetales @@ -493,7 +500,13 @@ http://purl.obolibrary.org/obo/NCBITaxon_4894 Schizosaccharomycetaceae http://purl.obolibrary.org/obo/NCBITaxon_4895 Schizosaccharomyces http://purl.obolibrary.org/obo/NCBITaxon_4896 Schizosaccharomyces pombe http://purl.obolibrary.org/obo/NCBITaxon_554915 Amoebozoa +http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea +http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa +http://purl.obolibrary.org/obo/NCBITaxon_6231 Nematoda +http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida +http://purl.obolibrary.org/obo/NCBITaxon_6237 Caenorhabditis +http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata @@ -527,6 +540,7 @@ http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0001579 contractility +http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0001873 cylindrical @@ -545,6 +559,7 @@ http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0002124 laminar http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance http://purl.obolibrary.org/obo/PATO_0002226 subcylindrical +http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002309 fiber shaped diff --git a/src/ontology/subsets/general_cell_types_upper_slim.json b/src/ontology/subsets/general_cell_types_upper_slim.json index 577a04942..a718314a3 100644 --- a/src/ontology/subsets/general_cell_types_upper_slim.json +++ b/src/ontology/subsets/general_cell_types_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2025-12-17" + "val" : "2026-03-17" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2025-12-17/subsets/general_cell_types_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2026-03-17/subsets/general_cell_types_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -40,7 +40,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { - "val" : "FBbt:00007002" + "val" : "FBbt:00007002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:68646" }, { @@ -56,7 +62,13 @@ }, { "val" : "XAO:0003012" }, { - "val" : "ZFA:0009000" + "val" : "ZFA:0009000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -74,7 +86,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009002" + "val" : "ZFA:0009002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -90,10 +108,9 @@ "val" : "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, - "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { - "pred" : "hasExactSynonym", + "pred" : "hasNarrowSynonym", "val" : "animal stem cell" } ], "xrefs" : [ { @@ -101,7 +118,13 @@ }, { "val" : "FMA:63368" }, { - "val" : "ZFA:0005957" + "val" : "ZFA:0005957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -111,7 +134,13 @@ "val" : "Stem cells are a unique type of cell that has the remarkable ability to divide and develop into many different types of cells in the body. These cells are undifferentiated, meaning they haven't yet developed into a specific cell type, and they can renew themselves through cell division. As a result, stem cells have the potential to replace damaged or diseased cells in the body, making them a valuable tool in medicine and research.\nThere are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos and can develop into any type of cell in the body. Adult stem cells, on the other hand, are found in various tissues and organs throughout the body and can only develop into certain types of cells.\nStem cells have numerous potential applications in medicine, including the treatment of various diseases and the repair of damaged tissues. For example, they could be used to replace damaged heart tissue after a heart attack or to repair spinal cord injuries. Stem cells also have potential uses in drug development and disease research, as they can be used to model diseases and test potential therapies in vitro.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stem cell" @@ -153,7 +182,13 @@ }, { "val" : "VHOG:0001485" }, { - "val" : "ZFA:0009014" + "val" : "ZFA:0009014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -163,7 +198,13 @@ "val" : "Hematopoietic stem cells (HSCs) are multipotent cells, capable of differentiating into a wide variety of specialized blood cells. During embryonic development hematopoietic stem cells emerge from the hemogenic endothelium, a specialized subset of endothelial cells with hematopoietic potential. HSCs can be found in several organs, in particular in bone marrow, as well as peripheral blood and umbilical cord blood.\nThese stem cells have a distinctive ability to self-renew, and to differentiate into all lymphoid and myeloid cell types that together form the blood and immune systems including erythrocytes (red blood cells), leukocytes (white blood cells), and platelets. Their primary function is to ensure the continuous replenishment of the blood and immune system throughout an individual's lifespan.\nIn response to various signals, hematopoietic stem cells can either remain dormant or actively divide and differentiate. Under normal conditions, the majority of these stem cells exist in a quiescent (inactive) state, making them somewhat resistant to chemotherapy or radiation therapy in the treatment of various diseases such as leukemia. However, when the body encounters stress such as infection, bleeding, or disease, hematopoietic stem cells can rapidly become active in order to replenish the affected cells and maintain homeostasis.\nFurthermore, hematopoietic stem cells are extremely important in the field of regenerative medicine and transplantation. Regarded as lifesaving in the field of oncology, they are often extracted, purified, and reinfused back into the same (autologous transplantation) or different (allogeneic transplantation) individuals to reestablish a healthy, functioning hematopoietic and immune system after high-dose chemotherapy or to replace dysfunctional bone marrow. Understanding and manipulating the behavior of these stem cells has immense potential in treating various blood disorders, autoimmune diseases, and cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "hematopoietic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "hematopoietic stem cell" @@ -203,14 +244,26 @@ "xrefs" : [ { "val" : "BTO:0004911" }, { - "val" : "ZFA:0009015" + "val" : "ZFA:0009015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Erythroid progenitor cells play a key role in the hematopoietic system, specifically in the process of erythropoiesis – the production of red blood cells (erythrocytes). Found within the bone marrow, these cells are dedicated precursors to erythrocytes, and ensue in the hematopoietic lineage from multipotent progenitors. They represent a transitional cell type that bridges the gap between the early-stage erythroid precursors and the maturing red blood cell population.\nThe earliest committed erythroid progenitor cell is thought to be the burst-forming unit-erythroid (BFU-E) cell, which after several cell divisions gives rise to another erythroid progenitor, the colony-forming unit-erythroid (CFU-E) cell. \nErythroid progenitor cells are primarily responsible for responding to the demand for new red blood cells during conditions of physiological stress like infection, blood loss, or illness. This responsive behavior is regulated by a glycoprotein hormone known as erythropoietin, which is produced by the kidneys. Erythropoietin interacts with the receptors on the erythroid progenitor cells, prompting them to proliferate and differentiate into erythroblasts. The erythroblasts then further mature, eventually producing new, functional red cells.\nThe role of erythroid progenitor cells extends beyond their main function of erythrocyte production, as they also participate in maintaining the balance of iron in the body. Upon erythroid differentiation, they increase their uptake of transferrin-bound iron for hemoglobin synthesis, a vital component of red blood cells which allows them to transport oxygen. A deficiency or excess of erythroid progenitor cells can lead to extensive health issues such as anemia or polycythemia respectively, emphasizing their crucial role in human health.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythroid progenitor cell" @@ -228,7 +281,13 @@ "comments" : [ "Originally this term had some plant germ line cell children." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { - "val" : "ZFA:0009016" + "val" : "ZFA:0009016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -261,7 +320,13 @@ "xrefs" : [ { "val" : "FMA:84789" }, { - "val" : "ZFA:0009020" + "val" : "ZFA:0009020", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -317,7 +382,13 @@ "xrefs" : [ { "val" : "BTO:0004730" }, { - "val" : "ZFA:0009021" + "val" : "ZFA:0009021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -327,7 +398,13 @@ "val" : "The common myeloid progenitor (CMP) is a multipotent cell that serves as a crucial intermediary within the overall framework of hematopoietic cell differentiation, which is the process of blood cell production. This part of the hematopoiesis process leads to the formation of myeloid lineage cells, which includes granulocytes (neutrophils, eosinophils, and basophils), monocytes, erythrocytes (red blood cells), and megakaryocytes (platelet-forming cells). \nThe primary function of common myeloid progenitors is differentiation and proliferation into various types of mature blood cells, thereby providing a critical contribution to maintaining homeostasis within the body's immune and circulatory systems. Single-cell analyses have shown that the CMP cell population is heterogeneous with at least two distinct subpopulations, characterized by different cell surface markers and likely already committed to downstream differentiation into either the granulocyte/macrophage lineage or the megakaryocyte/erythrocyte lineage-restricted progenitor. \nThe destiny of a CMP is influenced by numerous cytokines and growth factors in its environment that promote differentiation along specific lineages. For example, IL-3 and GM-CSF stimulate the production of eosinophils, which are essential for the body’s defense against allergens and help fight fungal and parasitic infections. \nBy being able to differentiate into a wide range of different immune cells, common myeloid progenitors play a crucial role in the body's ability to respond to injuries, infections, and other physiological challenges.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "common myeloid progenitor on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "common myeloid progenitor" @@ -367,7 +444,13 @@ "val" : "megakaryocyte/erythroid progenitor cell" } ], "xrefs" : [ { - "val" : "ZFA:0009022" + "val" : "ZFA:0009022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -377,7 +460,13 @@ "val" : "The megakaryocyte-erythroid progenitor (MEP) cell belongs to the multipotent hematopoietic progenitor cells, which can give rise to multiple different cell types. They are found in the bone marrow, the primary organ where new blood cells are generated. MEPs are specially programmed to develop into two distinct blood cell lineages, namely megakaryocytes, which go on to produce platelets for blood clotting, and the erythroid lineage which consists of red blood cells responsible for oxygen transport in the body.\nThe MEP cells are the result of a decision-making process within the hematopoietic stem cell population. Hematopoietic stem cell can differentiate into multiple types of progenitor cells, including myeloid progenitor cells. A further subdivision within this myeloid lineage generates the MEP cells. Therefore, these megakaryocyte-erythroid progenitors represent a key juncture between hematopoietic stem cells and mature blood cell types in the myeloid lineage.\nMegakaryocyte-erythroid progenitor cells play a crucial role in the homeostasis of some of the most crucial constituents of blood. The megakaryocytes produced from these bipotent progenitor cells contribute to hemostasis by producing platelets - small anucleated fragments that are pivotal for blood clotting and preventing bleeding. Similarly, the erythroid lineage from MEP cells gives rise to erythrocytes, which harbor hemoglobin, the molecule that transports oxygen from lungs to every nook and corner of the body. An imbalance or malfunction in MEP function thus can significantly impact human health, leading to diseases like thrombocytopenia or anemia.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte-erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "megakaryocyte-erythroid progenitor cell" @@ -402,7 +491,13 @@ }, { "val" : "MESH:D039901" }, { - "val" : "ZFA:0009024" + "val" : "ZFA:0009024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -424,13 +519,25 @@ }, { "val" : "CALOHA:TS-0650" }, { - "val" : "FBbt:00005083" + "val" : "FBbt:00005083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:70335" }, { "val" : "VHOG:0001529" }, { - "val" : "ZFA:0009025" + "val" : "ZFA:0009025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -459,7 +566,13 @@ }, { "val" : "VHOG:0001482" }, { - "val" : "ZFA:0009026" + "val" : "ZFA:0009026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -490,13 +603,25 @@ }, { "val" : "CARO:0000077" }, { - "val" : "FBbt:00000124" + "val" : "FBbt:00000124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:66768" }, { "val" : "WBbt:0003672" }, { - "val" : "ZFA:0009034" + "val" : "ZFA:0009034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -520,7 +645,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009036" + "val" : "ZFA:0009036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -530,7 +661,13 @@ "val" : "Blood vessel endothelial cells, also known as vascular endothelial cells, form the delicate inner lining of the complex circulatory system, including arteries and veins. These cells form a single, continuous monolayer inside every blood vessel, acting as a crucial biomolecular barrier between the blood, and the rest of the body tissues. They perform various fundamental biological functions, ranging from maintenance of vessel integrity to blood clotting regulation. Additionally, they control the transportation of fluids, molecules, and blood particulate matter from and into the bloodstream.\nOne of the primary functions of blood vessel endothelial cells is to maintain vascular homeostasis - a stable environment within the blood vessels. They accomplish this through several methods: they control vasomotor tone, i.e. the degree of contraction and dilation of blood vessels, by secreting vasoactive substances such as nitric oxide and endothelin; mediate responses to inflammatory stimuli; and they also regulate angiogenesis, the process of new blood vessel formations. Blood vessel endothelial cells play a significant role in preventing blood clot formation by generating a slick, non-thrombogenic surface that disallows platelets or coagulant proteins from adhering to it.\nBlood vessel endothelial cells are sensitive to various stimuli, including shear stress caused by blood flow, and they can respond by altering their morphology, function, and gene expression. This ability to adapt enables blood vessels to remodel and ensure the adequate delivery of nutrients and oxygen to all tissues, regardless of physiological demand variations. Conversely, endothelial dysfunction, often associated with a reduction in the bioavailability of endothelium-derived nitric oxide, can lead to the development of pathological conditions such as atherosclerosis, hypertension, diabetes mellitus, and even aging-related diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "blood vessel endothelial cell" @@ -541,13 +678,25 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "definition" : { + "val" : "An epithelial cell that has a flattened morphology." + }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" }, { - "val" : "ZFA:0009039" + "val" : "ZFA:0009039", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/date", + "val" : "2025-12-16T15:56:39Z" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "squamous epithelial cell" } ] @@ -570,7 +719,13 @@ "xrefs" : [ { "val" : "FMA:66773" }, { - "val" : "ZFA:0009040" + "val" : "ZFA:0009040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -580,7 +735,13 @@ "val" : "Mesothelial cells are crucial components of the mesothelium, a protective layer that lines the body's internal cavities, including pleural cavity (around the lungs), the pericardial cavity (around the heart), and the peritoneal cavity (within the abdomen). Derived from the embryonic mesoderm layer, these cells exhibit a squamous-like epithelial morphology, usually appearing as a single layer of flat, pavement-like cells in their healthy state.\nMesothelial cells play a vital role in various physiological processes, such as intraperitoneal immunity, fibrinolysis, tissue repair, and tumor suppression. Their primary function is to provide a slippery, non-adhesive and protective surface to reduce friction and eases the movements of the organs within the pleural, pericardial, and peritoneal cavities, and they participate in the transport and movement of fluid and various molecules across the so-called serosal cavities. \nThese cells have adaptive capabilities that facilitate their role in many pathological processes. In response to injury or inflammation, mesothelial cells can undergo morphological and functional changes, such as mesothelial-mesenchymal transitions, aiding in wound healing and tissue repair. Dysfunctions of mesothelial cells, however, can lead to serious health conditions, including adhesions, fibrosis, and malignancies such as peritoneal and pleural mesotheliomas.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -598,7 +759,13 @@ }, { "val" : "MESH:D001773" }, { - "val" : "ZFA:0009044" + "val" : "ZFA:0009044", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -627,7 +794,13 @@ }, { "val" : "FMA:66772" }, { - "val" : "ZFA:0009065" + "val" : "ZFA:0009065", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -652,7 +825,13 @@ "val" : "neurectoderm cell" } ], "xrefs" : [ { - "val" : "ZFA:0009080" + "val" : "ZFA:0009080", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -724,14 +903,26 @@ }, { "val" : "FMA:70546" }, { - "val" : "ZFA:0009081" + "val" : "ZFA:0009081", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. These cells originate mainly from the mesoderm of the embryo, which forms connective tissues, muscle, and the circulatory and urinary systems. However, in adults, MSCs are found in multiple tissues, including bone marrow, adipose tissue, the umbilical cord, and dental tissues. \nThe primary function of MSCs is to maintain and repair the tissues in which they are found. When damage occurs, the MSCs are able to migrate to the site of injury, where they aid in regenerating the damaged tissue by differentiating into the required cell type and by secreting growth factors that enhance tissue repair and reduce inflammation. Furthermore, MSCs can also act as immunomodulators, suppressing immune reactions and reducing inflammation, both locally and systemically.\nApart from their role in tissue maintenance and repair, MSCs are integral to the field of regenerative medicine and are being investigated for their therapeutic potential in various clinical settings. Owing to their multipotent nature, immunomodulatory activity, and the relative ease of isolation, these cells can be engineered and translated into therapies to treat a variety of diseases, including bone and cartilage defects, liver diseases, heart disorders, and autoimmune diseases, amongst others. They have also been used as vectors for anticancer agents and in cell and gene therapy applications.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val" : "https://github.com/obophenotype/cell-ontology/issues/474" @@ -760,7 +951,13 @@ "xrefs" : [ { "val" : "VHOG:0001678" }, { - "val" : "ZFA:0009090" + "val" : "ZFA:0009090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -792,7 +989,13 @@ }, { "val" : "VHOG:0001679" }, { - "val" : "ZFA:0009091" + "val" : "ZFA:0009091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -802,7 +1005,13 @@ "val" : "Melanocytes are specialized cells prevalently found in the skin, but also present in the hair follicles, eyes, inner ear, bones, heart, and brain. Their primary function is the synthesis of melanin, a pigment responsible for coloration of skin, hair, and eyes. The presence and distribution of this pigment play a crucial role in the body's defense mechanism against harmful ultraviolet radiation.\nIn addition to melanin production, melanocytes also engage in a variety of other biological functions. They play a fundamental role in the immune response, owing to their ability to present antigens to T cells. Furthermore, they contribute to the maintenance of the skin's homeostasis by regulating processes such as extracellular matrix remodeling and cytokine production. A balance in melanocyte function is pivotal, as dysfunctions often result in dermatological disorders. For instance, the loss of melanocytes or reduction in their function may lead to hypopigmentation conditions such as vitiligo, whereas an abnormal increase could result in hyperpigmentation disorders or melanoma, a dangerous type of skin cancer.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000148" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000148", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "melanocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -856,7 +1065,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -871,15 +1080,30 @@ }, { "val" : "CALOHA:TS-2032" }, { - "val" : "FBbt:00005074" + "val" : "FBbt:00005074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67328" }, { "val" : "WBbt:0003675" }, { - "val" : "ZFA:0009114" + "val" : "ZFA:0009114", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle cell" }, { @@ -898,7 +1122,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009128" + "val" : "ZFA:0009128", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -921,7 +1151,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-0995" }, { - "val" : "ZFA:0009131" + "val" : "ZFA:0009131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -935,7 +1171,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009136" + "val" : "ZFA:0009136", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -959,7 +1201,13 @@ "xrefs" : [ { "val" : "FMA:72549" }, { - "val" : "ZFA:0009137" + "val" : "ZFA:0009137", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -986,14 +1234,26 @@ "xrefs" : [ { "val" : "FMA:72554" }, { - "val" : "ZFA:0009138" + "val" : "ZFA:0009138", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesodermal cells are pluripotent and the most abundant in the human body. They contribute to the development of several structures such as the skeletal muscles, bones, heart and blood vessels, kidneys, gonads, connective tissues, and certain layers of the skin. Hence, the mesoderm is often regarded as an active and diverse layer due to its role in forming many bodily structures. \nIn embryonic development, these cells are instrumental, contributing to the body's structures through a carefully coordinated sequence of morphogenetic movements. This process forms the complex multicellular architecture of tissues and organs from a simple ball of cells. Without the function of mesodermal cells, the body's integral structures and systems would cease to form correctly, leading to developmental disorders such as axial mesodermal dysplasia complex\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesodermal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesodermal cell" @@ -1016,7 +1276,13 @@ "xrefs" : [ { "val" : "FMA:72555" }, { - "val" : "ZFA:0009139" + "val" : "ZFA:0009139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1055,7 +1321,13 @@ "val" : "Erythrocytes, also known as red blood cells, are a type of specialized cell that make up the largest percentage of cells in the human body. Erythrocytes are biconcave in shape and lack nuclei and organelles, allowing them to carry oxygen and carbon dioxide through the bloodstream more efficiently. The main function of erythrocytes is to transport oxygen from the lungs to the body's tissues and organs, and to transport carbon dioxide from the body's tissues to the lungs, where it can be exhaled out of the body. Hemoglobin, a protein located inside erythrocytes, is responsible for binding to oxygen. \nErythrocytes are produced in the bone marrow and have a lifespan of approximately 120 days before they are broken down and recycled by the body. Erythrocytes are regulated by the hormone erythropoietin, which is produced by the kidneys and liver in response to low oxygen levels in the body, thereby stimulating erythrocyte production .\nIn addition to their role in oxygen transport, erythrocytes also play a key role in regulating the body's pH levels. Without erythrocytes, oxygen would not be able to be transported efficiently throughout the body and tissues would not receive the necessary oxygen to function properly. Overall, erythrocytes are essential for maintaining the health and homeostasis of the body.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythrocyte on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythrocyte" @@ -1125,7 +1397,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009164" + "val" : "ZFA:0009164", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1145,7 +1423,13 @@ "xrefs" : [ { "val" : "FMA:86667" }, { - "val" : "ZFA:0007086" + "val" : "ZFA:0007086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1163,7 +1447,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009166" + "val" : "ZFA:0009166", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1181,7 +1471,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009176" + "val" : "ZFA:0009176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1236,7 +1532,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009190" + "val" : "ZFA:0009190", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1254,7 +1556,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009193" + "val" : "ZFA:0009193", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1276,7 +1584,13 @@ }, { "val" : "FMA:83624" }, { - "val" : "ZFA:0009226" + "val" : "ZFA:0009226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1286,7 +1600,13 @@ "val" : "Stromal cells constitute a significant portion of the structural cellular milieu (stroma) that supports the function of parenchymal (functional) cells within an organ. The stroma is the connective, supportive framework of biological tissues with various functions depending on the specific organ and cell type. Stromal cells, derived from the mesenchymal lineage, play crucial roles in creating, maintaining, and repairing the tissue microenvironment in virtually all mammalian organs, making these cells indispensable to biological function.\nAdditionally, stromal cells secrete growth factors, cytokines, and extracellular matrix (ECM) molecules to constitute an interactive cellular network and ensure an optimal environment for the functional cells. Beyond mere structural support, these cells are instrumental in wound healing, inflammation, and maintaining tissue integrity. They may also influence the behavior of other cell types through direct cell-cell interactions or paracrine signaling.\nClinically and in research, stromal cells often draw attention due to their interaction with tumors in the cancer microenvironment. Over the past years, the role of stromal cells as facilitators of tumor growth and metastasis has been recognized increasingly. They contribute to cancer progression not only by modulating the ECM but also through the secretion of various bioactive molecules and interacting with immune cells, thereby influencing the immunologic responses to tumors.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stromal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stromal cell" @@ -1312,7 +1632,13 @@ }, { "val" : "CALOHA:TS-0683" }, { - "val" : "FBbt:00005106" + "val" : "FBbt:00005106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54527" }, { @@ -1320,7 +1646,13 @@ }, { "val" : "WBbt:0003679" }, { - "val" : "ZFA:0009248" + "val" : "ZFA:0009248", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1349,7 +1681,13 @@ }, { "val" : "FMA:83377" }, { - "val" : "ZFA:0009249" + "val" : "ZFA:0009249", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1408,7 +1746,13 @@ "xrefs" : [ { "val" : "FMA:83505" }, { - "val" : "ZFA:0005236" + "val" : "ZFA:0005236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1453,7 +1797,13 @@ "xrefs" : [ { "val" : "FMA:83506" }, { - "val" : "ZFA:0005241" + "val" : "ZFA:0005241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1594,7 +1944,13 @@ "val" : "A megakaryocyte is a large, unique, and complex cell type found primarily in the bone marrow, the spongy, semi-solid tissue located in the medullary cavities of certain bones. The term ‘megakaryocyte’ is derived from the Greek 'mega', meaning great, and 'karyon', referring to the nucleus. Megakaryocytes are characterized by their large size, typically with a diameter of 50-100 µm in humans, and the presence of a multilobulated nucleus; they are the largest hematopoietic cells in the bone marrow but also the rarest cells. \nThe primary function of a megakaryocyte is the production of platelets, also known as thrombocytes. Platelets are small, anucleate cell fragments that play a crucial role in the process of hemostasis, the arrest of blood loss from a damaged blood vessel. The process begins when the megakaryocyte extends long, branching processes called proplatelets, into the sinusoidal blood vessels present in the bone marrow. These proplatelets then fragment into the discoid structures recognized as platelets. Each megakaryocyte can produce thousands of platelets during its lifespan. \nApart from platelet production, megakaryocytes are involved in several other functions. They express immune-sensing receptors such as Fc-γ receptor and Toll-like receptors and produce factors such as platelet factor 4 and platelet-derived growth factor that can stimulate the immune system. Also, in certain pathological conditions, megakaryocytes release TGF-β and PDGF and contribute to bone marrow fibrosis, a condition characterized by excessive accumulation of fibrous tissue in the bone marrow leading to anemia. Recent studies have also highlighted the role of megakaryocytes in regulating hematopoiesis, the process of blood cell production. They can influence the bone marrow microenvironment and control the behavior of hematopoietic stem cells, the progenitors of all types of blood cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1614,7 +1970,13 @@ }, { "val" : "MESH:D012156" }, { - "val" : "ZFA:0009252" + "val" : "ZFA:0009252", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1640,7 +2002,13 @@ "val" : "chondroplast" } ], "xrefs" : [ { - "val" : "ZFA:0009258" + "val" : "ZFA:0009258", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1658,14 +2026,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009291" + "val" : "ZFA:0009291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Muscle precursor cells, commonly referred to as myogenic progenitor cells or myoblasts, play a pivotal role in the intricate processes of muscle regeneration and development. As undifferentiated cells, they harbor the potential to evolve into distinct specialized cells, specifically the muscle cell or myocyte. Their crucial contribution lies in guiding the transformation of the mesodermal layer, one of the three primary germ cell layers in the early embryo, into fully developed skeletal muscle tissues during embryonic development.\nMuscle precursor cells are characterized by their proliferative capacity and rapid differentiation into mature myocytes. They fuse into myotubes, culminating in the formation of muscle fibers. Their responsiveness to signals such as insulin-like growth factors, transforming growth factor-β, and neural inputs enables precise control over their proliferation and differentiation. This regenerative capacity equips them with the ability to repair injured or damaged muscle tissue, a critical function in preserving muscle homeostasis and overall function. These cells also actively contribute to adaptive responses, such as muscle growth and strengthening, in reaction to factors like training or aging.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "muscle precursor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle precursor cell" @@ -1686,14 +2066,26 @@ }, { "val" : "MESH:D053687" }, { - "val" : "ZFA:0009307" + "val" : "ZFA:0009307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Somatic stem cells, also known as adult stem cells, are undifferentiated cells found throughout the body post-embryonic development. They reside in specialized niches within tissues such as the bone marrow, brain, muscles, skin, and liver. Fundamentally, these cells possess the ability to self-renew, maintaining their numbers, and to generate differentiated cells that replace dying cells and repair damaged tissues. \nThe potency of somatic stem cells varies based on their tissue of origin. For instance, hematopoietic stem cells in the bone marrow exhibit multipotency, giving rise to all blood cell types. Conversely, muscle stem cells display unipotency, generating only muscle cells.\nSomatic stem cells respond to environmental signals that regulate their quiescence, activation, and differentiation states. In response to tissue injury, they proliferate and differentiate into specific mature cell types to replace lost or damaged cells. Intricate mechanisms ensure a delicate balance between self-renewal and differentiation, guiding tissue maintenance and repair without risking aberrant cell proliferation leading to tumor formation.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "somatic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somatic stem cell" @@ -1716,7 +2108,13 @@ }, { "val" : "MESH:D022423" }, { - "val" : "ZFA:0009324" + "val" : "ZFA:0009324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1745,7 +2143,13 @@ }, { "val" : "FMA:83516" }, { - "val" : "ZFA:0009325" + "val" : "ZFA:0009325", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1778,7 +2182,13 @@ }, { "val" : "MESH:D004900" }, { - "val" : "ZFA:0005237" + "val" : "ZFA:0005237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1808,7 +2218,13 @@ }, { "val" : "CALOHA:TS-0448" }, { - "val" : "ZFA:0009354" + "val" : "ZFA:0009354", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1840,7 +2256,13 @@ }, { "val" : "FMA:70339" }, { - "val" : "ZFA:0009356" + "val" : "ZFA:0009356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1879,7 +2301,13 @@ }, { "val" : "FMA:83598" }, { - "val" : "ZFA:0005830" + "val" : "ZFA:0005830", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1910,7 +2338,13 @@ "val" : "2011-11-16T04:28:16Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0001035" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0001035", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "bone cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1969,7 +2403,13 @@ "xrefs" : [ { "val" : "FMA:69074" }, { - "val" : "ZFA:0009385" + "val" : "ZFA:0009385", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -1999,7 +2439,13 @@ "xrefs" : [ { "val" : "FMA:69076" }, { - "val" : "ZFA:0009388" + "val" : "ZFA:0009388", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2045,7 +2491,13 @@ "val" : "2010-08-24T02:06:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "endothelial cell of vascular tree on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "endothelial cell of vascular tree" @@ -2118,7 +2570,13 @@ }, { "val" : "MESH:D003239" }, { - "val" : "ZFA:0009392" + "val" : "ZFA:0009392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2148,7 +2606,13 @@ }, { "val" : "WBbt:0007028" }, { - "val" : "ZFA:0007089" + "val" : "ZFA:0007089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2161,7 +2625,13 @@ "val" : "2010-09-15T03:39:21Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "embryonic cell (metazoa) on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "embryonic cell (metazoa)" @@ -2240,7 +2710,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007084" + "val" : "ZFA:0007084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2289,7 +2765,13 @@ "val" : "Mesenchymal cells are a type of undifferentiated cell that possess the ability to develop into a wide variety of other cells. These cells originate from the mesoderm during embryonic development, which gives rise to tissues such as muscles, the skeletal system, and connective and vascular structures. Mesenchymal cells primarily function as progenitor cells with exceptional renewal capabilities and are characterized by their ability to migrate, aiding in tissue repair and regeneration.\nMesenchymal cells play a critical role in the development and maintenance of various biological systems throughout the body due to their versatility and adaptability. They can differentiate into more specialized cells, including osteoblasts, adipocytes, and chondrocytes, which are essential for bone, fat, and cartilage tissues, respectively. Furthermore, they contribute to the vascular and lymphatic systems through the formation of pericytes and lymphatic endothelial cells, securing the integrity of the circulatory system.\nIn the field of regenerative medicine, mesenchymal cells, particularly mesenchymal stem cells (MSCs), are of great interest due to their unique therapeutic potential. MSCs, for instance, have been implicated in wound healing and tissue repair because of their capacity to modulate the immune response. They can secrete a range of proteins and growth factors that aid in angiogenesis, the formation of new blood vessels, and the stimulation of resident progenitor cells to aid in tissue restoration.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesenchymal cell" @@ -2330,7 +2812,13 @@ "val" : "Neural crest cells are a group of transient and highly migratory cells that originate from the neuroectoderm during the early stages of embryonic development. They are multipotent cells with an exceptional degree of plasticity, capable of differentiating into various somatic cell types and therefore play a fundamental role in the formation of various organs and tissues, making them critical contributors to the developing embryo. \nAfter the initiation of neurulation (the formation of the neural tube) neural crest cells start to undergo epithelial-to-mesenchymal transition and delaminate and migrate from the dorsal neural tube to several regions throughout the embryo. They differentiate into a range of diverse cell types, such as neurons and glial cells of the peripheral nervous system, including sensory and autonomic neurons. They also contribute to the formation of adrenal glands, pigment cells in the skin (melanocytes), cardiac structures, including parts of the heart septum and major arteries, as well as bones and cartilage of the face and skull.\nDisorders or aberrations in the development or migration of the neural crest cells can lead to serious congenital malformations, such as neurocristopathies, including Hirschsprung disease, neuroblastoma, and neurofibromatosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "neural crest cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "neural crest cell" @@ -2448,7 +2936,13 @@ }, { "val" : "MetaCyc:PEPTIDYLTRANSFERASE-RXN" }, { - "val" : "Reactome:R-HSA-156912" + "val" : "Reactome:R-HSA-156912", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Peptide transfer from P-site tRNA to the A-site tRNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -2456,6 +2950,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25493" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -2504,7 +3001,13 @@ "val" : "mitosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-69278" + "val" : "Reactome:R-HSA-69278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle, Mitotic" + } ] + } }, { "val" : "Wikipedia:Mitosis" } ], @@ -2694,7 +3197,13 @@ "xrefs" : [ "GOC:dph", "GOC:sdb_2009", "GOC:tb" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9823730" + "val" : "Reactome:R-HSA-9823730", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Formation of definitive endoderm" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3005,6 +3514,9 @@ "val" : "molecular function" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is the same as GO molecular function" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -3632,7 +4144,13 @@ "val" : "protein translation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72766" + "val" : "Reactome:R-HSA-72766", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Translation" + } ] + } }, { "val" : "Wikipedia:Translation_(genetics)" } ], @@ -3665,7 +4183,13 @@ "val" : "translation initiation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72613" + "val" : "Reactome:R-HSA-72613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Initiation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3690,7 +4214,13 @@ "val" : "translation elongation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-156842" + "val" : "Reactome:R-HSA-156842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Elongation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3717,7 +4247,13 @@ "val" : "translational complex disassembly" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72764" + "val" : "Reactome:R-HSA-72764", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Termination" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3771,7 +4307,13 @@ "val" : "single-organism transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382551" + "val" : "Reactome:R-HSA-382551", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of small molecules" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -3799,7 +4341,13 @@ "val" : "ion transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-425393" + "val" : "Reactome:R-HSA-425393", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of inorganic cations/anions and amino acids/oligopeptides" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3867,7 +4415,13 @@ "val" : "signaling (initiator) caspase activity" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-109581" + "val" : "Reactome:R-HSA-109581", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptosis" + } ] + } }, { "val" : "Wikipedia:Apoptosis" } ], @@ -3917,7 +4471,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-445355" + "val" : "Reactome:R-HSA-445355", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Smooth Muscle Contraction" + } ] + } }, { "val" : "Wikipedia:Muscle_contraction" } ], @@ -3965,7 +4525,13 @@ "val" : "single-organism organelle organization" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1852241" + "val" : "Reactome:R-HSA-1852241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Organelle biogenesis and maintenance" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -3993,7 +4559,13 @@ "val" : "cell-division cycle" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1640170" + "val" : "Reactome:R-HSA-1640170", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle" + } ] + } }, { "val" : "Wikipedia:Cell_cycle" } ], @@ -4067,7 +4639,13 @@ "val" : "signalling pathway" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-212718" + "val" : "Reactome:R-HSA-212718", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "EGFR interacts with phospholipase C-gamma" + } ] + } }, { "val" : "Wikipedia:Signal_transduction" } ], @@ -4117,23 +4695,77 @@ "xrefs" : [ "GOC:dph" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-112316" - }, { - "val" : "Reactome:R-HSA-442720" - }, { - "val" : "Reactome:R-HSA-442729" - }, { - "val" : "Reactome:R-HSA-442742" - }, { - "val" : "Reactome:R-HSA-451307" - }, { - "val" : "Reactome:R-HSA-451308" - }, { - "val" : "Reactome:R-HSA-9619229" - }, { - "val" : "Reactome:R-HSA-9619483" - }, { - "val" : "Reactome:R-HSA-9620244" + "val" : "Reactome:R-HSA-112316", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Neuronal System" + } ] + } + }, { + "val" : "Reactome:R-HSA-442720", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through the activation of Adenylate Cyclase" + } ] + } + }, { + "val" : "Reactome:R-HSA-442729", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde" + } ] + } + }, { + "val" : "Reactome:R-HSA-442742", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" + } ] + } + }, { + "val" : "Reactome:R-HSA-451307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of Na-permeable kainate receptors" + } ] + } + }, { + "val" : "Reactome:R-HSA-451308", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of Ca-permeable Kainate Receptor" + } ] + } + }, { + "val" : "Reactome:R-HSA-9619229", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of RAC1 downstream of NMDARs" + } ] + } + }, { + "val" : "Reactome:R-HSA-9619483", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of AMPK downstream of NMDARs" + } ] + } + }, { + "val" : "Reactome:R-HSA-9620244", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Long-term potentiation" + } ] + } }, { "val" : "Wikipedia:Neurotransmission" } ], @@ -4184,7 +4816,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila" ], "xrefs" : [ { - 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"val" : "Reactome:R-HSA-159431" - }, { - "val" : "Reactome:R-HSA-192312" - }, { - "val" : "Reactome:R-HSA-193491" - }, { - "val" : "Reactome:R-HSA-8858298" + "val" : "Reactome:R-HSA-159431", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine" + } ] + } + }, { + "val" : "Reactome:R-HSA-192312", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate" + } ] + } + }, { + "val" : "Reactome:R-HSA-193491", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate" + } ] + } + }, { + "val" : "Reactome:R-HSA-8858298", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "HRASLS transfer acyl group from PC to PE to form NAPE" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/20486" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -5236,6 +5968,9 @@ "val" : "EC:2.3.2.-" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -5320,7 +6055,13 @@ "val" : "multicellular organismal protein metabolic process" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-392499" + "val" : "Reactome:R-HSA-392499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of proteins" + } ] + } }, { "val" : "Wikipedia:Protein_metabolism" } ], @@ -5560,7 +6301,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -5574,6 +6315,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/26279" }, { @@ -5590,6 +6334,7 @@ "val" : "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:18391171" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "formation of a cell surface projection" @@ -5599,6 +6344,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -6176,6 +6924,9 @@ "val" : "protein-protein complex" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is not covalently bonded, which conflicts with changes to the parent definition." + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -6240,7 +6991,13 @@ "val" : "ATP hydrolysis coupled ion transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-983712" + "val" : "Reactome:R-HSA-983712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ion channel transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -6369,6 +7126,9 @@ "val" : "Wikipedia:Melanosome" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002161", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6237" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -6379,8 +7139,8 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "Any biological process involved in the maintenance of an internal steady state.", - "xrefs" : [ "GOC:jl", "ISBN:0395825172" ] + "val" : "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions.", + "xrefs" : [ "PMID:26265027" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_mouse" ], "synonyms" : [ { @@ -6403,6 +7163,9 @@ "val" : "regulation of homeostatic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/31175" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -6526,7 +7289,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -6538,6 +7301,9 @@ "val" : "cellular projection" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" }, { @@ -7639,7 +8405,13 @@ "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953897" + "val" : "Reactome:R-HSA-8953897", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cellular responses to stimuli" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -7665,11 +8437,29 @@ "val" : "ATP hydrolysis coupled transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382556" + "val" : "Reactome:R-HSA-382556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ABC-family proteins mediated transport" + } ] + } }, { - "val" : "Reactome:R-HSA-425407" + "val" : "Reactome:R-HSA-425407", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "SLC-mediated transmembrane transport" + } ] + } }, { - "val" : "Reactome:R-HSA-5223345" + "val" : "Reactome:R-HSA-5223345", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Miscellaneous transport and binding events" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", @@ -8099,11 +8889,29 @@ "val" : "induction of apoptosis by extracellular signals" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-193681" + "val" : "Reactome:R-HSA-193681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ceramide signalling" + } ] + } }, { - "val" : "Reactome:R-HSA-204998" + "val" : "Reactome:R-HSA-204998", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell death signalling via NRAGE, NRIF and NADE" + } ] + } }, { - "val" : "Reactome:R-HSA-75157" + "val" : "Reactome:R-HSA-75157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "FasL/ CD95L signaling" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -8133,7 +8941,13 @@ "val" : "apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-75153" + "val" : "Reactome:R-HSA-75153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptotic execution phase" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -8238,7 +9052,7 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098643", - "lbl" : "fibrillar collagen", + "lbl" : "fibrillar collagen complex", "type" : "CLASS", "meta" : { "definition" : { @@ -8248,6 +9062,9 @@ "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "banded collagen fibril" + }, { + "pred" : "hasExactSynonym", + "val" : "fibrillar collagen" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -8291,14 +9108,21 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098645", - "lbl" : "collagen network", + "lbl" : "complex of network-forming collagens", "type" : "CLASS", "meta" : { "definition" : { "val" : "A supramolecular complex that consists of collagen triple helices associated to form a network.", "xrefs" : [ "GOC:dos", "PMID:21421911" ] }, + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "collagen network" + } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30938" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -8405,8 +9229,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.", - "xrefs" : [ "GOC:kmv" ] + "val" : "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { @@ -8414,6 +9237,12 @@ "val" : "cellular anatomical entity" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Overlaps with some cellular components from GO" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" }, { @@ -9004,6 +9833,37 @@ "val" : "Euteleostomi" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_119089", + "lbl" : "Chromadorea", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Adenophorea" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794", + "lbl" : "Ecdysozoa", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_131567", "lbl" : "cellular organisms", @@ -9223,6 +10083,32 @@ "val" : "ncbi_taxonomy" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116", + "lbl" : "Rhabditina", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119", + "lbl" : "Rhabditomorpha", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "lbl" : "Eukaryota", @@ -9268,6 +10154,46 @@ "val" : "Eukaryota" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "lbl" : "Choanoflagellata", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "choanoflagellates" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellatea" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellida" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanomonada" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanozoa" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "choanoflagellates" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + }, { + "val" : "PMID:27765632" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "lbl" : "Euarchontoglires", @@ -9460,6 +10386,19 @@ "val" : "Bilateria" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_33317", + "lbl" : "Protostomia", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_33511", "lbl" : "Deuterostomia", @@ -9719,6 +10658,32 @@ "val" : "ncbi_taxonomy" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_55879", + "lbl" : "Rhabditoidea", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_55885", + "lbl" : "Peloderinae", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6072", "lbl" : "Eumetazoa", @@ -9735,6 +10700,88 @@ "val" : "Eumetazoa" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6231", + "lbl" : "Nematoda", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "nematode" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "nematodes" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "roundworm" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "roundworms" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Nemata" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "nematodes" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6236", + "lbl" : "Rhabditida", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Strongylida" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6237", + "lbl" : "Caenorhabditis", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6243", + "lbl" : "Rhabditidae", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_7711", "lbl" : "Chordata", @@ -10305,6 +11352,21 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0001591", + "lbl" : "curvature", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.", + "xrefs" : [ "WordNet:WordNet" ] + }, + "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0001690", "lbl" : "contractile", @@ -10600,6 +11662,32 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0002254", + "lbl" : "flattened", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane.", + "xrefs" : [ "PATOC:CVS" ] + }, + "comments" : [ "Becoming flat but not necessarily completely flat." ], + "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], + "synonyms" : [ { + "pred" : "hasRelatedSynonym", + "val" : "compressed" + } ], + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0002-2061-091X" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2010-08-16T03:59:34Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002266", "lbl" : "3-D shape", @@ -11951,7 +13039,13 @@ }, { "val" : "TAO:0005425" }, { - "val" : "UMLS:C0036760" + "val" : "UMLS:C0036760", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Serosa" + } ] + } }, { "val" : "Wikipedia:Serous_membrane" }, { @@ -12017,7 +13111,13 @@ "xrefs" : [ { "val" : "AAO:0011123" }, { - "val" : "FBbt:00100314" + "val" : "FBbt:00100314", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:30320" }, { @@ -12027,7 +13127,13 @@ }, { "val" : "TAO:0005171" }, { - "val" : "UMLS:C0687028" + "val" : "UMLS:C0687028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Duct" + } ] + } }, { "val" : "Wikipedia:Duct_(anatomy)" }, { @@ -12107,7 +13213,13 @@ }, { "val" : "FAO:0000001" }, { - "val" : "FBbt:00007001" + "val" : "FBbt:00007001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:305751" }, { @@ -12192,7 +13304,13 @@ }, { "val" : "SCTID:272625005" }, { - "val" : "UMLS:C0178784" + "val" : "UMLS:C0178784", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ" + } ] + } }, { "val" : "WBbt:0003760" }, { @@ -12200,7 +13318,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33090" @@ -12320,47 +13444,161 @@ }, { "val" : "BilaDO:0000004" }, { - "val" : "BtauDv:0000078" - }, { - "val" : "CfamDv:0000007" - }, { - "val" : "ChirDv:0000014" - }, { - "val" : "DpseDv:0000005" - }, { - "val" : "DsimDv:0000005" + "val" : "BtauDv:0000078", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001272" }, { - "val" : "EcabDv:0000007" + "val" : "EcabDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005369" }, { - "val" : "FcatDv:0000007" - }, { - "val" : "GgalDv:0000076" - }, { - "val" : "GgorDv:0000032" - }, { - "val" : "HsapDv:0010000" - }, { - "val" : "MmulDv:0000052" - }, { - "val" : "MmusDv:0000092" - }, { - "val" : "OanaDv:0000007" - }, { - "val" : "OariDv:0000024" - }, { - "val" : "PpanDv:0000041" - }, { - "val" : "PtroDv:0000052" - }, { - "val" : "RnorDv:0000061" - }, { - "val" : "SsalDv:0000040" - }, { - "val" : "SscrDv:0000084" + "val" : "FcatDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000076", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000032", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0010000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000041", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000061", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000041" }, { @@ -12391,65 +13629,203 @@ "val" : "embryogenesis" } ], "xrefs" : [ { - "val" : "AcarDv:0000002" + "val" : "AcarDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BilaDO:0000002" }, { - "val" : "BtauDv:0000002" - }, { - "val" : "CfamDv:0000002" - }, { - "val" : "ChirDv:0000002" - }, { - "val" : "CporDv:0000002" - }, { - "val" : "DpseDv:0000002" - }, { - "val" : "DsimDv:0000002" + "val" : "BtauDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EV:0300001" }, { - "val" : "EcabDv:0000002" + "val" : "EcabDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005289" }, { "val" : "FMA:72652" }, { - "val" : "FcatDv:0000002" - }, { - "val" : "GgalDv:0000002" - }, { - "val" : "GgorDv:0000002" - }, { - "val" : "HsapDv:0000045" - }, { - "val" : "MdomDv:0000002" - }, { - "val" : "MmulDv:0000002" - }, { - "val" : "MmusDv:0000042" + "val" : "FcatDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000045", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000042", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000000" }, { "val" : "OGES:000022" }, { - "val" : "OanaDv:0000002" - }, { - "val" : "OariDv:0000002" - }, { - "val" : "OcunDv:0000002" - }, { - "val" : "PpanDv:0000002" - }, { - "val" : "PtroDv:0000002" - }, { - "val" : "RnorDv:0000002" + "val" : "OanaDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : 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"val" : "SscrDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000003" }, { @@ -12522,7 +13898,13 @@ }, { "val" : "SCTID:118966000" }, { - "val" : "UMLS:C1519343" + "val" : "UMLS:C1519343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System_Part" + } ] + } }, { "val" : "galen:ComplexSkeletalStructure" } ], @@ -12559,7 +13941,13 @@ }, { "val" : "OGES:000024" }, { - "val" : "SsalDv:0000038" + "val" : "SsalDv:0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000022" }, { @@ -12629,55 +14017,193 @@ "val" : "lifespan" } ], "xrefs" : [ { - "val" : "AcarDv:0000001" - }, { - "val" : "BtauDv:0000001" - }, { - "val" : "CfamDv:0000001" - }, { - "val" : "ChirDv:0000001" - }, { - "val" : "CporDv:0000001" - }, { - "val" : "DpseDv:0000001" - }, { - "val" : "DsimDv:0000001" - }, { - "val" : "EcabDv:0000001" + "val" : "AcarDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "BtauDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "EcabDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00000000" }, { - "val" : "FcatDv:0000001" - }, { - "val" : "GgalDv:0000001" - }, { 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"val" : "MdomDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000011" }, { - "val" : "OanaDv:0000001" - }, { - "val" : "OariDv:0000001" - }, { - "val" : "OcunDv:0000001" - }, { - "val" : "PpanDv:0000001" - }, { - "val" : "PtroDv:0000001" - }, { - "val" : "RnorDv:0000001" - }, { - "val" : "SsalDv:0000001" - }, { - "val" : "SscrDv:0000001" + "val" : "OanaDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "ncithesaurus:Life" } ], @@ -12716,63 +14242,201 @@ "val" : "stage" } ], "xrefs" : [ { - "val" : "AcarDv:0000000" + "val" : "AcarDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BILS:0000105" }, { - "val" : "BtauDv:0000000" - }, { - "val" : "CfamDv:0000000" - }, { - "val" : "ChirDv:0000000" - }, { - "val" : "CporDv:0000000" - }, { - "val" : "DpseDv:0000000" - }, { - "val" : "DsimDv:0000000" + "val" : "BtauDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0000399" }, { - "val" : "EcabDv:0000000" + "val" : "EcabDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00007012" }, { "val" : "FMA:24120" }, { - "val" : "FcatDv:0000000" - }, { - "val" : "GgalDv:0000000" - }, { - "val" : "GgorDv:0000000" - }, { - "val" : "HsapDv:0000000" + "val" : "FcatDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D008018" }, { - "val" : "MdomDv:0000000" - }, { - "val" : "MmulDv:0000000" - }, { - "val" : "MmusDv:0000000" - }, { - "val" : "OanaDv:0000000" - }, { - "val" : "OariDv:0000000" - }, { - "val" : "OcunDv:0000000" + "val" : "MdomDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000090" }, { - "val" : "PpanDv:0000000" - }, { - "val" : "PtroDv:0000000" - }, { - "val" : "RnorDv:0000000" - }, { - "val" : "SsalDv:0000000" - }, { - "val" : "SscrDv:0000000" + "val" : "PpanDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000002" }, { @@ -12843,7 +14507,13 @@ }, { "val" : "BilaDO:0000005" }, { - "val" : "ChirDv:0000003" + "val" : "ChirDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001322" }, { @@ -12851,21 +14521,57 @@ }, { "val" : "FBdv:00005288" }, { - "val" : "HsapDv:0000003" - }, { - "val" : "MmusDv:0000003" + "val" : "HsapDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "NCIT:C12601" }, { - "val" : "OariDv:0000009" + "val" : "OariDv:0000009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000100" }, { - "val" : "RnorDv:0000048" - }, { - "val" : "SsalDv:0000003" - }, { - "val" : "SscrDv:0000087" + "val" : "RnorDv:0000048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "VHOG:0000745" }, { @@ -12898,33 +14604,81 @@ }, { "val" : "BilaDO:0000006" }, { - "val" : "ChirDv:0000004" + "val" : "ChirDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001290" }, { "val" : "FBdv:00000054" }, { - "val" : "GgalDv:0000064" - }, { - "val" : "HsapDv:0000005" + "val" : "GgalDv:0000064", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D002970" }, { - "val" : "MmusDv:0000004" + "val" : "MmusDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000015" }, { "val" : "OGES:000020" }, { - "val" : "OariDv:0000010" + "val" : "OariDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000200" }, { - "val" : "RnorDv:0000049" - }, { - "val" : "SsalDv:0000004" - }, { - "val" : "SscrDv:0000088" + "val" : "RnorDv:0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000088", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Cleavage_(embryo)" }, { @@ -12952,15 +14706,39 @@ }, { "val" : "BilaDO:0000007" }, { - "val" : "ChirDv:0000010" + "val" : "ChirDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001282" }, { - "val" : "GgalDv:0000091" - }, { - "val" : "HsapDv:0000006" - }, { - "val" : "MmusDv:0000007" + "val" : "GgalDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000003" }, { @@ -12968,13 +14746,37 @@ }, { "val" : "OGES:000021" }, { - "val" : "OariDv:0000025" - }, { - "val" : "RnorDv:0000054" - }, { - "val" : "SsalDv:0000012" - }, { - "val" : "SscrDv:0000089" + "val" : "OariDv:0000025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000005" }, { @@ -13035,29 +14837,77 @@ }, { "val" : "BilaDO:0000008" }, { - "val" : "ChirDv:0000011" + "val" : "ChirDv:0000011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001296" }, { "val" : "FBdv:00005317" }, { - "val" : "GgalDv:0000092" - }, { - "val" : "HsapDv:0000010" - }, { - "val" : "MmusDv:0000013" + "val" : "GgalDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000004" }, { "val" : "OGES:000019" }, { - "val" : "OariDv:0000026" - }, { - "val" : "RnorDv:0000005" - }, { - "val" : "SsalDv:0000016" - }, { - "val" : "SscrDv:0000090" + "val" : "OariDv:0000026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000010" }, { @@ -13084,19 +14934,61 @@ }, { "val" : "BilaDO:0000009" }, { - "val" : "ChirDv:0000012" - }, { - "val" : "GgalDv:0000093" - }, { - "val" : "HsapDv:0000012" - }, { - "val" : "MmusDv:0000017" - }, { - "val" : "OariDv:0000027" - }, { - "val" : "RnorDv:0000007" - }, { - "val" : "SscrDv:0000091" + "val" : "ChirDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "XAO:1000006" } ], @@ -13129,25 +15021,73 @@ }, { "val" : "BilaDO:0000010" }, { - "val" : "ChirDv:0000013" - }, { - "val" : "GgalDv:0000094" - }, { - "val" : "HsapDv:0000015" - }, { - "val" : "MmusDv:0000018" + "val" : "ChirDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000018", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000005" }, { "val" : "OGES:000032" }, { - "val" : "OariDv:0000028" - }, { - "val" : "RnorDv:0000055" - }, { - "val" : "SsalDv:0000022" - }, { - "val" : "SscrDv:0000086" + "val" : "OariDv:0000028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Organogenesis" } ], @@ -13246,7 +15186,13 @@ }, { "val" : "EMAPA:16262" }, { - "val" : "FBbt:00003126" + "val" : "FBbt:00003126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:49184" }, { @@ -13362,7 +15308,13 @@ }, { "val" : "TAO:0000007" }, { - "val" : "UMLS:C0005767" + "val" : "UMLS:C0005767", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood" + } ] + } }, { "val" : "VHOG:0000224" }, { @@ -13552,7 +15504,13 @@ "xrefs" : [ { "val" : "BTO:0001837" }, { - "val" : "EMAPA:37950" + "val" : "EMAPA:37950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:62889" }, { @@ -13621,7 +15579,13 @@ }, { "val" : "NCIT:C34062" }, { - "val" : "UMLS:C1516992" + "val" : "UMLS:C1516992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland_Fluid_or_Secretion" + } ] + } }, { "val" : "galen:Secretion" } ], @@ -13676,7 +15640,13 @@ }, { "val" : "EMAPA:35178" }, { - "val" : "FBbt:00007019" + "val" : "FBbt:00007019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9669" }, { @@ -13750,7 +15720,13 @@ }, { "val" : "EHDAA2:0003005" }, { - "val" : "FBbt:00007017" + "val" : "FBbt:00007017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:5897" }, { @@ -13762,7 +15738,13 @@ }, { "val" : "TGMA:0001825" }, { - "val" : "UMLS:C0524461" + "val" : "UMLS:C0524461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lumen_Space" + } ] + } }, { "val" : "VHOG:0001728" }, { @@ -13805,7 +15787,13 @@ }, { "val" : "EHDAA2:0003006" }, { - "val" : "FBbt:00007016" + "val" : "FBbt:00007016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67165" }, { @@ -13857,7 +15845,13 @@ }, { "val" : "EHDAA2:0003007" }, { - "val" : "FBbt:00007015" + "val" : "FBbt:00007015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67112" }, { @@ -13937,7 +15931,13 @@ }, { "val" : "EV:0100000" }, { - "val" : "FBbt:00004856" + "val" : "FBbt:00004856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7149" }, { @@ -13953,7 +15953,13 @@ }, { "val" : "TGMA:0001831" }, { - "val" : "UMLS:C0460002" + "val" : "UMLS:C0460002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_System" + } ] + } }, { "val" : "VHOG:0001725" }, { @@ -14051,7 +16057,13 @@ }, { "val" : "EV:0100016" }, { - "val" : "FBbt:00000001" + "val" : "FBbt:00000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:256135" }, { @@ -14143,7 +16155,13 @@ }, { "val" : "EMAPA:36031" }, { - "val" : "FBbt:00007009" + "val" : "FBbt:00007009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7153" }, { @@ -14163,7 +16181,13 @@ }, { "val" : "TGMA:0001840" }, { - "val" : "UMLS:C0229962" + "val" : "UMLS:C0229962", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Body_Part" + } ] + } }, { "val" : "VHOG:0001758" }, { @@ -14219,7 +16243,13 @@ }, { "val" : "EHDAA2:0003040" }, { - "val" : "FBbt:00007013" + "val" : "FBbt:00007013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:63863" }, { @@ -14258,7 +16288,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007277" + "val" : "FBbt:00007277", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "VHOG:0001737" } ], @@ -14314,7 +16350,13 @@ }, { "val" : "EHDAA:46" }, { - "val" : "FBbt:00005835" + "val" : "FBbt:00005835", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85537" }, { @@ -14328,7 +16370,13 @@ }, { "val" : "TGMA:0001843" }, { - "val" : "UMLS:C1282438" + "val" : "UMLS:C1282438", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Extraembryonic_Structure" + } ] + } }, { "val" : "VHOG:0000292" }, { @@ -14382,7 +16430,13 @@ }, { "val" : "EMAPA:35868" }, { - "val" : "FBbt:00007003" + "val" : "FBbt:00007003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9637" }, { @@ -14398,7 +16452,13 @@ }, { "val" : "TGMA:0001844" }, { - "val" : "UMLS:C0040300" + "val" : "UMLS:C0040300", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Tissue" + } ] + } }, { "val" : "VHOG:0001757" }, { @@ -14454,7 +16514,13 @@ }, { "val" : "EHDAA2:0003055" }, { - "val" : "FBbt:00007010" + "val" : "FBbt:00007010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000055" }, { @@ -14520,7 +16586,13 @@ }, { "val" : "EMAPA:32738" }, { - "val" : "FBbt:00007005" + "val" : "FBbt:00007005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9639" }, { @@ -14538,7 +16610,13 @@ }, { "val" : "TAO:0001486" }, { - "val" : "UMLS:C0014609" + "val" : "UMLS:C0014609", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Epithelium" + } ] + } }, { "val" : "VHOG:0000387" }, { @@ -14597,7 +16675,13 @@ }, { "val" : "TAO:0001494" }, { - "val" : "UMLS:C0682575" + "val" : "UMLS:C0682575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stratified_Epithelium" + } ] + } }, { "val" : "Wikipedia:Stratified_epithelium" }, { @@ -14650,7 +16734,13 @@ }, { "val" : "TAO:0001498" }, { - "val" : "UMLS:C0836133" + "val" : "UMLS:C0836133", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_squamous_epithelium" }, { @@ -14709,7 +16799,13 @@ }, { "val" : "TAO:0001495" }, { - "val" : "UMLS:C0682574" + "val" : "UMLS:C0682574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Epithelium" + } ] + } }, { "val" : "XAO:0004007" }, { @@ -14809,7 +16905,13 @@ }, { "val" : "EMAPA:16039" }, { - "val" : "FBbt:00000052" + "val" : "FBbt:00000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69068" }, { @@ -14827,7 +16929,13 @@ }, { "val" : "SCTID:57991002" }, { - "val" : "UMLS:C0013935" + "val" : "UMLS:C0013935", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryo" + } ] + } }, { "val" : "VHOG:0001766" }, { @@ -14889,7 +16997,13 @@ }, { "val" : "EMAPA:36033" }, { - "val" : "FBbt:00000110" + "val" : "FBbt:00000110", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69069" }, { @@ -14903,9 +17017,21 @@ }, { "val" : "TAO:0001122" }, { - "val" : "UMLS:C0920502" - }, { - "val" : "UMLS:C1708239" + "val" : "UMLS:C0920502", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Tissue" + } ] + } + }, { + "val" : "UMLS:C1708239", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Germinal_Layer" + } ] + } }, { "val" : "VHOG:0001223" }, { @@ -14952,7 +17078,13 @@ }, { "val" : "EV:0100003" }, { - "val" : "FBbt:00000111" + "val" : "FBbt:00000111", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69070" }, { @@ -14972,7 +17104,13 @@ }, { "val" : "TAO:0000016" }, { - "val" : "UMLS:C0013574" + "val" : "UMLS:C0013574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ectoderm" + } ] + } }, { "val" : "VHOG:0000153" }, { @@ -15023,7 +17161,13 @@ }, { "val" : "EV:0100005" }, { - "val" : "FBbt:00000125" + "val" : "FBbt:00000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69071" }, { @@ -15041,7 +17185,13 @@ }, { "val" : "TAO:0000017" }, { - "val" : "UMLS:C0014144" + "val" : "UMLS:C0014144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endoderm" + } ] + } }, { "val" : "VHOG:0000154" }, { @@ -15107,7 +17257,13 @@ }, { "val" : "EV:0100006" }, { - "val" : "FBbt:00000126" + "val" : "FBbt:00000126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69072" }, { @@ -15125,7 +17281,13 @@ }, { "val" : "TAO:0000041" }, { - "val" : "UMLS:C0025485" + "val" : "UMLS:C0025485", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesoderm" + } ] + } }, { "val" : "VHOG:0000152" }, { @@ -15195,7 +17357,13 @@ }, { "val" : "EMAPA:16263" }, { - "val" : "FBbt:00000439" + "val" : "FBbt:00000439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:295846" }, { @@ -15205,7 +17373,13 @@ }, { "val" : "TGMA:0000135" }, { - "val" : "UMLS:C1514977" + "val" : "UMLS:C1514977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stomodeum" + } ] + } }, { "val" : "Wikipedia:Stomodeum" }, { @@ -15288,7 +17462,13 @@ }, { "val" : "TAO:0000114" }, { - "val" : "UMLS:C0018787" + "val" : "UMLS:C0018787", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Heart" + } ] + } }, { "val" : "VHOG:0000276" }, { @@ -15379,7 +17559,13 @@ }, { "val" : "TAO:0000367" }, { - "val" : "UMLS:C0022417" + "val" : "UMLS:C0022417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint" + } ] + } }, { "val" : "VHOG:0001276" }, { @@ -15432,7 +17618,13 @@ }, { "val" : "EFO:0000793" }, { - "val" : "FBbt:00005055" + "val" : "FBbt:00005055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7152" }, { @@ -15493,7 +17685,13 @@ }, { "val" : "CALOHA:TS-2103" }, { - "val" : "MESH:D002319" + "val" : "MESH:D002319", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "VHOG:0001248" }, { @@ -15501,7 +17699,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6073" @@ -15573,7 +17777,13 @@ }, { "val" : "TAO:0000548" }, { - "val" : "UMLS:C0026845" + "val" : "UMLS:C0026845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle" + } ] + } }, { "val" : "VSAO:0005038" }, { @@ -15636,7 +17846,13 @@ }, { "val" : "EV:0100162" }, { - "val" : "FBbt:00005093" + "val" : "FBbt:00005093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7157" }, { @@ -15656,7 +17872,13 @@ }, { "val" : "TAO:0000396" }, { - "val" : "UMLS:C0027763" + "val" : "UMLS:C0027763", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System" + } ] + } }, { "val" : "VHOG:0000402" }, { @@ -15740,7 +17962,13 @@ }, { "val" : "EV:0100163" }, { - "val" : "FBbt:00005094" + "val" : "FBbt:00005094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:55675" }, { @@ -15758,7 +17986,16 @@ }, { "val" : "TAO:0000012" }, { - "val" : "UMLS:C0927232" + "val" : "UMLS:C0927232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1099" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Central_Nervous_System" + } ] + } }, { "val" : "VHOG:0000293" }, { @@ -15772,7 +18009,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -15819,7 +18062,13 @@ }, { "val" : "EHDAA2:0003171" }, { - "val" : "FBbt:00005495" + "val" : "FBbt:00005495", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86589" }, { @@ -15827,7 +18076,13 @@ }, { "val" : "NCIT:C34275" }, { - "val" : "UMLS:C0678727" + "val" : "UMLS:C0678727", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium" + } ] + } }, { "val" : "Wikipedia:Primordium" }, { @@ -15891,7 +18146,13 @@ }, { "val" : "TAO:0001135" }, { - "val" : "UMLS:C0231024" + "val" : "UMLS:C0231024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Tube" + } ] + } }, { "val" : "VHOG:0000307" }, { @@ -15936,7 +18197,13 @@ }, { "val" : "EHDAA2:0002229" }, { - "val" : "FBbt:10000000" + "val" : "FBbt:10000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:62955" }, { @@ -15950,7 +18217,13 @@ }, { "val" : "TGMA:0001822" }, { - "val" : "UMLS:C1515976" + "val" : "UMLS:C1515976", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Structure_System_or_Substance" + } ] + } }, { "val" : "WBbt:0000100" }, { @@ -16006,7 +18279,13 @@ }, { "val" : "TAO:0005154" }, { - "val" : "UMLS:C0039097" + "val" : "UMLS:C0039097", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Synovial_Fluid" + } ] + } }, { "val" : "Wikipedia:Synovial_fluid" }, { @@ -16060,7 +18339,13 @@ }, { "val" : "SCTID:361918002" }, { - "val" : "UMLS:C0086610" + "val" : "UMLS:C0086610", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesothelium" + } ] + } }, { "val" : "Wikipedia:Mesothelium" } ], @@ -16115,7 +18400,13 @@ }, { "val" : "TAO:0000434" }, { - "val" : "UMLS:C0037253" + "val" : "UMLS:C0037253", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System" + } ] + } }, { "val" : "VHOG:0001254" }, { @@ -16197,7 +18488,13 @@ }, { "val" : "TAO:0001514" }, { - "val" : "UMLS:C0262950" + "val" : "UMLS:C0262950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bone" + } ] + } }, { "val" : "VHOG:0001190" }, { @@ -16247,7 +18544,13 @@ "xrefs" : [ "Wikipedia:Articular_capsule" ] } ], "xrefs" : [ { - "val" : "EMAPA:37621" + "val" : "EMAPA:37621", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:34836" }, { @@ -16263,7 +18566,13 @@ }, { "val" : "SCTID:182238002" }, { - "val" : "UMLS:C0206207" + "val" : "UMLS:C0206207", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint_Capsule" + } ] + } }, { "val" : "Wikipedia:Articular_capsule" }, { @@ -16329,13 +18638,25 @@ }, { "val" : "EMAPA:16247" }, { - "val" : "FBbt:00003125" + "val" : "FBbt:00003125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45615" }, { "val" : "MA:0000917" }, { - "val" : "MESH:D041981" + "val" : "MESH:D041981", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C34082" }, { @@ -16343,7 +18664,13 @@ }, { "val" : "TGMA:0001819" }, { - "val" : "UMLS:C0017189" + "val" : "UMLS:C0017189", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrointestinal_Tract" + } ] + } }, { "val" : "VHOG:0000309" }, { @@ -16355,10 +18682,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1371/journal.pone.0016309" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -16383,7 +18722,13 @@ "xrefs" : [ "ZFA:0005145" ] } ], "xrefs" : [ { - "val" : "EMAPA:37474" + "val" : "EMAPA:37474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100146" }, { @@ -16473,7 +18818,13 @@ }, { "val" : "TAO:0000005" }, { - "val" : "UMLS:C0003842" + "val" : "UMLS:C0003842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Artery" + } ] + } }, { "val" : "VHOG:0001251" }, { @@ -16562,7 +18913,13 @@ }, { "val" : "TAO:0000082" }, { - "val" : "UMLS:C0042449" + "val" : "UMLS:C0042449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vein" + } ] + } }, { "val" : "VHOG:0001743" }, { @@ -16633,7 +18990,13 @@ }, { "val" : "NCIT:C13356" }, { - "val" : "UMLS:C0032105" + "val" : "UMLS:C0032105", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Plasma" + } ] + } }, { "val" : "Wikipedia:Blood_plasma" } ], @@ -16675,7 +19038,13 @@ }, { "val" : "TAO:0005315" }, { - "val" : "UMLS:C0042520" + "val" : "UMLS:C0042520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venule" + } ] + } }, { "val" : "VHOG:0001765" }, { @@ -16729,7 +19098,13 @@ }, { "val" : "TAO:0002138" }, { - "val" : "UMLS:C0003847" + "val" : "UMLS:C0003847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Arteriole" + } ] + } }, { "val" : "VHOG:0001763" }, { @@ -16812,7 +19187,13 @@ }, { "val" : "TAO:0002137" }, { - "val" : "UMLS:C0005847" + "val" : "UMLS:C0005847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel" + } ] + } }, { "val" : "VHOG:0001250" }, { @@ -16878,7 +19259,13 @@ }, { "val" : "TAO:0005250" }, { - "val" : "UMLS:C0935624" + "val" : "UMLS:C0935624", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary" + } ] + } }, { "val" : "VHOG:0001253" }, { @@ -16933,7 +19320,13 @@ }, { "val" : "SCTID:27168002" }, { - "val" : "UMLS:C0014257" + "val" : "UMLS:C0014257", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endothelium" + } ] + } }, { "val" : "galen:Endothelium" } ], @@ -17025,7 +19418,13 @@ }, { "val" : "EFO:0000461" }, { - "val" : "FBbt:00004208" + "val" : "FBbt:00004208", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69067" }, { @@ -17041,7 +19440,13 @@ }, { "val" : "TAO:0001105" }, { - "val" : "UMLS:C0013948" + "val" : "UMLS:C0013948", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Structure" + } ] + } }, { "val" : "VSAO:0000178" }, { @@ -17105,7 +19510,13 @@ }, { "val" : "SCTID:118760003" }, { - "val" : "UMLS:C0042779" + "val" : "UMLS:C0042779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Viscera" + } ] + } }, { "val" : "Wikipedia:Viscus" }, { @@ -17144,7 +19555,13 @@ }, { "val" : "EHDAA:5049" }, { - "val" : "EMAPA:37721" + "val" : "EMAPA:37721", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71221" }, { @@ -17152,7 +19569,13 @@ }, { "val" : "MAT:0000148" }, { - "val" : "MESH:D013131" + "val" : "MESH:D013131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000148" }, { @@ -17226,7 +19649,13 @@ }, { "val" : "TAO:0001115" }, { - "val" : "UMLS:C0460005" + "val" : "UMLS:C0460005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trunk" + } ] + } }, { "val" : "Wikipedia:Torso" }, { @@ -17313,7 +19742,13 @@ }, { "val" : "SCTID:278858007" }, { - "val" : "UMLS:C0026860" + "val" : "UMLS:C0026860", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Musculoskeletal_System" + } ] + } }, { "val" : "VHOG:0001275" }, { @@ -17439,7 +19874,13 @@ }, { "val" : "SCTID:243949006" }, { - "val" : "UMLS:C0230139" + "val" : "UMLS:C0230139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Thoracic_Cavity" + } ] + } }, { "val" : "Wikipedia:Thoracic_cavity" } ], @@ -17511,7 +19952,13 @@ }, { "val" : "EHDAA2:0000267" }, { - "val" : "FBbt:00005060" + "val" : "FBbt:00005060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85006" }, { @@ -17523,7 +19970,13 @@ }, { "val" : "TAO:0001438" }, { - "val" : "UMLS:C0333343" + "val" : "UMLS:C0333343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cavity" + } ] + } }, { "val" : "galen:BodyCavity" } ], @@ -17587,7 +20040,13 @@ }, { "val" : "TAO:0000135" }, { - "val" : "UMLS:C0028439" + "val" : "UMLS:C0028439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochord" + } ] + } }, { "val" : "VHOG:0000199" }, { @@ -17683,7 +20142,13 @@ }, { "val" : "TAO:0000155" }, { - "val" : "UMLS:C0376449" + "val" : "UMLS:C0376449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somite" + } ] + } }, { "val" : "VHOG:0000191" }, { @@ -17695,7 +20160,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:17237766" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somite" @@ -17732,7 +20203,13 @@ }, { "val" : "NCIT:C12957" }, { - "val" : "UMLS:C1516995" + "val" : "UMLS:C1516995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_System" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" }, { @@ -17797,7 +20274,13 @@ }, { "val" : "SCTID:361462002" }, { - "val" : "UMLS:C0027789" + "val" : "UMLS:C0027789", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Crest" + } ] + } }, { "val" : "VHOG:0000057" }, { @@ -17869,7 +20352,13 @@ }, { "val" : "EV:0100004" }, { - "val" : "FBbt:00001057" + "val" : "FBbt:00001057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:87657" }, { @@ -17881,7 +20370,13 @@ }, { "val" : "TAO:0001120" }, { - "val" : "UMLS:C1518271" + "val" : "UMLS:C1518271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neuroectoderm" + } ] + } }, { "val" : "VHOG:0000150" }, { @@ -17939,7 +20434,13 @@ }, { "val" : "SCTID:115976003" }, { - "val" : "UMLS:C0015282" + "val" : "UMLS:C0015282", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" } ], @@ -18002,7 +20503,13 @@ }, { "val" : "TAO:0001641" }, { - "val" : "UMLS:C0009780" + "val" : "UMLS:C0009780", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Connective_Tissue" + } ] + } }, { "val" : "VSAO:0000017" }, { @@ -18070,7 +20577,13 @@ }, { "val" : "SCTID:91727004" }, { - "val" : "UMLS:C2328219" + "val" : "UMLS:C2328219", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle_Tissue" + } ] + } }, { "val" : "Wikipedia:Muscle_tissue" }, { @@ -18148,7 +20661,13 @@ }, { "val" : "TAO:0005023" }, { - "val" : "UMLS:C0018957" + "val" : "UMLS:C0018957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hematopoietic_System" + } ] + } }, { "val" : "VHOG:0001624" }, { @@ -18212,7 +20731,13 @@ }, { "val" : "NCIT:C13076" }, { - "val" : "UMLS:C0391978" + "val" : "UMLS:C0391978", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bone_Tissue" + } ] + } }, { "val" : "VSAO:0000047" }, { @@ -18271,7 +20796,13 @@ }, { "val" : "EMAPA:18425" }, { - "val" : "FBbt:00100317" + "val" : "FBbt:00100317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7146" }, { @@ -18289,7 +20820,13 @@ }, { "val" : "SCTID:134358001" }, { - "val" : "UMLS:C1285092" + "val" : "UMLS:C1285092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gland" + } ] + } }, { "val" : "Wikipedia:Gland" }, { @@ -18377,7 +20914,13 @@ "xrefs" : [ { "val" : "BIRNLEX:1011" }, { - "val" : "EMAPA:37442" + "val" : "EMAPA:37442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67552" }, { @@ -18495,7 +21038,13 @@ }, { "val" : "TE:E5.11.2.0.0.0.4" }, { - "val" : "UMLS:C1511224" + "val" : "UMLS:C1511224", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Island" + } ] + } }, { "val" : "VHOG:0000085" }, { @@ -18590,7 +21139,13 @@ }, { "val" : "TAO:0000132" }, { - "val" : "UMLS:C0920623" + "val" : "UMLS:C0920623", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Plate" + } ] + } }, { "val" : "VHOG:0000068" }, { @@ -18651,7 +21206,13 @@ }, { "val" : "TAO:0000255" }, { - "val" : "UMLS:C1284009" + "val" : "UMLS:C1284009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Paraxial_Mesoderm" + } ] + } }, { "val" : "VHOG:0000114" }, { @@ -18718,7 +21279,13 @@ }, { "val" : "TAO:0000121" }, { - "val" : "UMLS:C1517749" + "val" : "UMLS:C1517749", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lateral_Mesoderm" + } ] + } }, { "val" : "VHOG:0000118" }, { @@ -18763,7 +21330,13 @@ }, { "val" : "TAO:0000028" }, { - "val" : "UMLS:C1514450" + "val" : "UMLS:C1514450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium_of_the_Heart" + } ] + } }, { "val" : "XAO:0000336" }, { @@ -18813,7 +21386,13 @@ }, { "val" : "TAO:0001080" }, { - "val" : "UMLS:C0183176" + "val" : "UMLS:C0183176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclerotome" + } ] + } }, { "val" : "VHOG:0000680" }, { @@ -18920,7 +21499,13 @@ }, { "val" : "TAO:0000393" }, { - "val" : "UMLS:C0162415" + "val" : "UMLS:C0162415", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesenchyme" + } ] + } }, { "val" : "VHOG:0000170" }, { @@ -19006,7 +21591,13 @@ }, { "val" : "NCIT:C34195" }, { - "val" : "UMLS:C1512940" + "val" : "UMLS:C1512940", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intraembryonic_Coelom" + } ] + } }, { "val" : "VHOG:0000316" }, { @@ -19038,7 +21629,13 @@ }, { "val" : "EHDAA2:0003114" }, { - "val" : "FBbt:00007474" + "val" : "FBbt:00007474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -19467,7 +22064,13 @@ }, { "val" : "TAO:0000010" }, { - "val" : "UMLS:C0007226" + "val" : "UMLS:C0007226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiovascular_System" + } ] + } }, { "val" : "VHOG:0000302" }, { @@ -19593,7 +22196,13 @@ }, { "val" : "SCTID:362060003" }, { - "val" : "UMLS:C1267406" + "val" : "UMLS:C1267406", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venous_System" + } ] + } }, { "val" : "VHOG:0000277" } ], @@ -19625,7 +22234,13 @@ }, { "val" : "TAO:0005257" }, { - "val" : "UMLS:C1706972" + "val" : "UMLS:C1706972", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel_Endothelium" + } ] + } }, { "val" : "ZFA:0005257" } ], @@ -19663,7 +22278,13 @@ }, { "val" : "NCIT:C34131" }, { - "val" : "UMLS:C1516779" + "val" : "UMLS:C1516779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conceptus" + } ] + } }, { "val" : "Wikipedia:Conceptus" } ], @@ -19727,7 +22348,13 @@ }, { "val" : "BTO:0001403" }, { - "val" : "FBbt:00005317" + "val" : "FBbt:00005317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:293108" }, { @@ -19741,9 +22368,21 @@ }, { "val" : "NCIT:C34058" }, { - "val" : "UMLS:C0017199" - }, { - "val" : "UMLS:C1284022" + "val" : "UMLS:C0017199", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrula" + } ] + } + }, { + "val" : "UMLS:C1284022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trilaminar_Embryonic_Disc" + } ] + } }, { "val" : "Wikipedia:Gastrula" }, { @@ -19765,7 +22404,13 @@ }, "comments" : [ "Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from" ], "xrefs" : [ { - "val" : "EMAPA:37744" + "val" : "EMAPA:37744", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0003047" }, { @@ -19887,7 +22532,13 @@ }, { "val" : "TAO:0002171" }, { - "val" : "UMLS:C0014261" + "val" : "UMLS:C0014261", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_Endothelium" + } ] + } }, { "val" : "VHOG:0001217" }, { @@ -19996,7 +22647,13 @@ "val" : "joint" } ], "xrefs" : [ { - "val" : "FBbt:00005811" + "val" : "FBbt:00005811", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -20033,7 +22690,13 @@ "xrefs" : [ "FMA:71131" ] } ], "xrefs" : [ { - "val" : "FBbt:00100315" + "val" : "FBbt:00100315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:71131" } ], @@ -20086,7 +22749,13 @@ }, { "val" : "SCTID:361463007" }, { - "val" : "UMLS:C0814992" + "val" : "UMLS:C0814992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Groove" + } ] + } }, { "val" : "Wikipedia:Neural_groove" }, { @@ -20123,7 +22792,13 @@ }, { "val" : "SCTID:361461009" }, { - "val" : "UMLS:C0814993" + "val" : "UMLS:C0814993", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Fold" + } ] + } }, { "val" : "Wikipedia:Neural_fold" }, { @@ -20221,7 +22896,13 @@ "xrefs" : [ "MA:0000516" ] } ], "xrefs" : [ { - "val" : "EMAPA:37270" + "val" : "EMAPA:37270", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000516" } ], @@ -20246,7 +22927,13 @@ "xrefs" : [ "MA:0000557" ] } ], "xrefs" : [ { - "val" : "EMAPA:37273" + "val" : "EMAPA:37273", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000557" } ], @@ -20271,7 +22958,13 @@ "xrefs" : [ "MA:0000563" ] } ], "xrefs" : [ { - "val" : "EMAPA:37271" + "val" : "EMAPA:37271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000563" } ], @@ -20365,7 +23058,13 @@ }, { "val" : "EHDAA2:0003125" }, { - "val" : "FBbt:00007006" + "val" : "FBbt:00007006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:292313" }, { @@ -20489,13 +23188,25 @@ }, { "val" : "SCTID:68989006" }, { - "val" : "UMLS:C0004799" + "val" : "UMLS:C0004799", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Basement_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "http://palaeos.com/metazoa/porifera/homoscleromorpha.html" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "basement membrane of epithelium" @@ -20554,7 +23265,13 @@ }, { "val" : "SCTID:361725000" }, { - "val" : "UMLS:C0222645" + "val" : "UMLS:C0222645", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Axial_Skeleton" + } ] + } }, { "val" : "VSAO:0000056" }, { @@ -20598,7 +23315,13 @@ }, { "val" : "NCIT:C34231" }, { - "val" : "UMLS:C1518429" + "val" : "UMLS:C1518429", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Plate" + } ] + } }, { "val" : "VHOG:0001212" } ], @@ -20639,7 +23362,13 @@ }, { "val" : "NCIT:C34232" }, { - "val" : "UMLS:C1518430" + "val" : "UMLS:C1518430", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Process" + } ] + } }, { "val" : "VHOG:0001213" } ], @@ -20669,7 +23398,13 @@ "xrefs" : [ { "val" : "BIRNLEX:20" }, { - "val" : "EMAPA:37441" + "val" : "EMAPA:37441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:280556" }, { @@ -20837,7 +23572,13 @@ }, { "val" : "SCTID:40118003" }, { - "val" : "UMLS:C0221909" + "val" : "UMLS:C0221909", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Squamous_epithelium" } ], @@ -20890,7 +23631,13 @@ }, { "val" : "NCIT:C34022" }, { - "val" : "UMLS:C1515977" + "val" : "UMLS:C1515977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Surface" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -21009,7 +23756,13 @@ }, { "val" : "SCTID:360394002" }, { - "val" : "UMLS:C1514442" + "val" : "UMLS:C1514442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordial_Gut" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -21360,7 +24113,13 @@ }, { "val" : "EHDAA2:0003170" }, { - "val" : "FBbt:00005426" + "val" : "FBbt:00005426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "Wikipedia:Anlage_(biology)" } ], @@ -21447,7 +24206,13 @@ }, { "val" : "NCIT:C33854" }, { - "val" : "UMLS:C0489903" + "val" : "UMLS:C0489903", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_System" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -21604,7 +24369,13 @@ "xrefs" : [ { "val" : "CARO:0010000" }, { - "val" : "FBbt:00100313" + "val" : "FBbt:00100313", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -21827,7 +24598,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007330" + "val" : "FBbt:00007330", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67509" }, { @@ -21893,7 +24670,13 @@ "val" : "main body segment" } ], "xrefs" : [ { - "val" : "FBbt:00057001" + "val" : "FBbt:00057001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -21948,7 +24731,13 @@ }, { "val" : "NCIT:C32450" }, { - "val" : "UMLS:C1511770" + "val" : "UMLS:C1511770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Dense_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Dense_connective_tissue" } ], @@ -22039,7 +24828,13 @@ "val" : "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "coelom" @@ -22322,7 +25117,13 @@ "xrefs" : [ "MA:0002449" ] } ], "xrefs" : [ { - "val" : "EMAPA:37597" + "val" : "EMAPA:37597", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002449" } ], @@ -22480,7 +25281,13 @@ "xrefs" : [ { "val" : "CARO:0020000" }, { - "val" : "FBbt:00007276" + "val" : "FBbt:00007276", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -24085,7 +26892,13 @@ "meta" : { "definition" : { "val" : "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -24101,7 +26914,13 @@ "meta" : { "definition" : { "val" : "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -24409,7 +27228,7 @@ } }, { "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym", - "lbl" : "has_narrow_synonym", + "lbl" : "has narrow synonym", "type" : "PROPERTY", "propertyType" : "ANNOTATION", "meta" : { @@ -24528,22 +27347,18 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000007", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0002321" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0011115" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", - "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0017145" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000037", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000037", "pred" : "is_a", @@ -24714,6 +27529,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000076", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000066" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000076", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000077", "pred" : "is_a", @@ -24954,6 +27773,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000219" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000333", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", @@ -25034,6 +27857,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000540", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0019226" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000541", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000541", "pred" : "is_a", @@ -25378,6 +28205,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000566", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", "obj" : "http://purl.obolibrary.org/obo/CL_0000134" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000680", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000680", "pred" : "is_a", @@ -25716,6 +28547,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0007004", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", @@ -25760,10 +28595,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0011026", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", @@ -26050,7 +28881,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0032991" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005581", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "pred" : "http://purl.obolibrary.org/obo/RO_0002160", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005587", @@ -26420,6 +29251,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008015", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/GO_0003013" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0008150", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", + "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -27892,6 +30727,14 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_117571", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_117570" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_119089", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6231" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33317" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_131567", "pred" : "is_a", @@ -27916,10 +30759,22 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6236" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33154" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "pred" : "is_a", @@ -27952,6 +30807,10 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33213", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6072" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33317", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33213" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33511", "pred" : "is_a", @@ -28004,10 +30863,34 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_554915", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2759" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_55879", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_55885", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6243" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6072", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6231", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6236", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_119089" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6237", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_55885" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6243", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_55879" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_7711", "pred" : "is_a", @@ -28116,6 +30999,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0001579", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0001591", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0000052" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0001690", "pred" : "is_a", @@ -28188,6 +31075,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002198", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0002254", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001591" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002266", "pred" : "is_a", @@ -32808,6 +35699,13 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0001981" } ] + }, { + "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000076", + "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], + "restrictions" : [ { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002254" + } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000081", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -34702,6 +37600,13 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" } ] + }, { + "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", + "allValuesFromEdges" : [ { + "sub" : "http://purl.obolibrary.org/obo/GO_0005581", + "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062", "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], diff --git a/src/ontology/subsets/general_cell_types_upper_slim.obo b/src/ontology/subsets/general_cell_types_upper_slim.obo index e3520614d..9dc0c5130 100644 --- a/src/ontology/subsets/general_cell_types_upper_slim.obo +++ b/src/ontology/subsets/general_cell_types_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2025-12-17/subsets/general_cell_types_upper_slim.owl +data-version: cl/releases/2026-03-17/subsets/general_cell_types_upper_slim.owl idspace: dc http://purl.org/dc/elements/1.1/ idspace: foaf http://xmlns.com/foaf/0.1/ idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# @@ -7,7 +7,7 @@ idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: terms http://purl.org/dc/terms/ ontology: cl/subsets/general_cell_types_upper_slim -property_value: owl:versionInfo "2025-12-17" xsd:string +property_value: owl:versionInfo "2026-03-17" xsd:string [Term] id: BFO:0000002 @@ -78,21 +78,18 @@ property_value: skos:prefLabel "early embryonic cell (metazoa)" xsd:string id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] -comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset -synonym: "animal stem cell" EXACT [] +synonym: "animal stem cell" NARROW [] xref: CALOHA:TS-2086 xref: FMA:63368 xref: ZFA:0005957 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa relationship: RO:0002215 GO:0017145 ! capable of stem cell division property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000034" xsd:string {name="stem cell on CELLxGENE CellGuide"} @@ -119,6 +116,7 @@ xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 xref: ZFA:0009014 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell @@ -360,13 +358,18 @@ property_value: terms:description "Blood vessel endothelial cells, also known as [Term] id: CL:0000076 name: squamous epithelial cell +def: "An epithelial cell that has a flattened morphology." [] subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: CALOHA:TS-1249 xref: ZFA:0009039 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell +intersection_of: CL:0000066 ! epithelial cell +intersection_of: RO:0000053 PATO:0002254 ! has characteristic flattened +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: skos:prefLabel "squamous epithelial cell" xsd:string +property_value: terms:date "2025-12-16T15:56:39Z" xsd:dateTime [Term] id: CL:0000077 @@ -547,6 +550,7 @@ name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset subset: general_cell_types_upper_slim +subset: human_reference_atlas subset: human_subset subset: mouse_subset synonym: "muscle fiber" EXACT [] @@ -564,6 +568,7 @@ is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell relationship: RO:0002202 CL:0000056 ! develops from myoblast property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI +property_value: RO:0002175 NCBITaxon:9606 property_value: skos:prefLabel "muscle cell" xsd:string [Term] @@ -738,6 +743,7 @@ subset: mouse_subset xref: FMA:86667 xref: ZFA:0007086 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell @@ -869,6 +875,7 @@ subset: mouse_subset xref: BTO:0003217 xref: FMA:83377 xref: ZFA:0009249 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell @@ -1145,6 +1152,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009291 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell @@ -1575,6 +1583,7 @@ subset: human_subset subset: mouse_subset xref: ZFA:0007084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: BFO:0000002 +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell @@ -1641,7 +1650,6 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset is_a: BFO:0000002 -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002202 CL:0000034 ! develops from stem cell @@ -1713,6 +1721,7 @@ is_a: GO:0140096 ! catalytic activity, acting on a protein is_a: GO:0140101 ! catalytic activity, acting on a tRNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0000262 @@ -2024,6 +2033,7 @@ subset: goslim_yeast synonym: "molecular function" EXACT [] disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process +property_value: IAO:0000116 "This is the same as GO molecular function" xsd:string [Term] id: GO:0003824 @@ -2060,6 +2070,9 @@ synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 +union_of: GO:0032991 ! protein-containing complex +union_of: GO:0044423 ! virion component +union_of: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0008150 ! biological_process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI @@ -2108,7 +2121,8 @@ namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa +relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa +relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0005587 @@ -2836,6 +2850,7 @@ synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process +relationship: BFO:0000051 GO:0003674 ! has part molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI creation_date: 2012-09-19T15:05:24Z @@ -3264,10 +3279,10 @@ subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" -xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016746 @@ -3284,6 +3299,7 @@ xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurin xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" is_a: GO:0016740 ! transferase activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016755 @@ -3293,6 +3309,7 @@ def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) synonym: "transferase activity, transferring amino-acyl groups" EXACT [] xref: EC:2.3.2.- is_a: GO:0016746 ! acyltransferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0017145 @@ -3496,6 +3513,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] @@ -3504,6 +3522,7 @@ is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] @@ -3511,6 +3530,7 @@ id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:18391171] +subset: gocheck_do_not_annotate synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly @@ -3518,6 +3538,7 @@ is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI [Term] id: GO:0030054 @@ -3835,6 +3856,7 @@ is_a: GO:0005575 ! cellular_component disjoint_from: GO:0044423 ! virion component disjoint_from: GO:0110165 ! cellular anatomical structure relationship: BFO:0000051 PR:000000001 ! has part protein +property_value: IAO:0000116 "This is not covalently bonded, which conflicts with changes to the parent definition." xsd:string [Term] id: GO:0034101 @@ -3943,12 +3965,13 @@ def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which mel xref: Wikipedia:Melanosome is_a: GO:0048770 ! pigment granule relationship: BFO:0000050 CL:0000148 ! part of melanocyte +property_value: RO:0002161 NCBITaxon:6237 [Term] id: GO:0042592 name: homeostatic process namespace: biological_process -def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] +def: "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." [PMID:26265027] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse @@ -3959,6 +3982,7 @@ synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological_process +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31175" xsd:anyURI [Term] id: GO:0042644 @@ -4025,6 +4049,7 @@ id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon @@ -4037,6 +4062,7 @@ synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: BFO:0000050 CL:0000000 ! part of cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: skos:prefLabel "cell projection" xsd:string [Term] @@ -4976,15 +5002,16 @@ def: "A collagen trimer that forms networks." [PMID:21421911] is_a: BFO:0000004 is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer -intersection_of: BFO:0000050 GO:0098645 ! part of collagen network -relationship: BFO:0000050 GO:0098645 ! part of collagen network +intersection_of: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens +relationship: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens [Term] id: GO:0098643 -name: fibrillar collagen +name: fibrillar collagen complex namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175] synonym: "banded collagen fibril" EXACT [] +synonym: "fibrillar collagen" EXACT [] is_a: GO:0098644 ! complex of collagen trimers relationship: BFO:0000050 GO:0140152 ! part of collagenous component of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI @@ -5005,10 +5032,12 @@ property_value: skos:prefLabel "complex of collagen trimers" xsd:string [Term] id: GO:0098645 -name: collagen network +name: complex of network-forming collagens namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] +synonym: "collagen network" EXACT [] is_a: GO:0098644 ! complex of collagen trimers +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30938" xsd:anyURI [Term] id: GO:0098793 @@ -5084,6 +5113,8 @@ subset: goslim_pir synonym: "cellular anatomical entity" EXACT [] is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure +property_value: IAO:0000116 "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." xsd:string +property_value: IAO:0000116 "Overlaps with some cellular components from GO" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28978" xsd:anyURI @@ -5238,7 +5269,7 @@ id: GO:0140154 name: chicken-wire-like collagen network namespace: cellular_component def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942] -is_a: GO:0098645 ! collagen network +is_a: GO:0098645 ! complex of network-forming collagens relationship: BFO:0000050 GO:0140143 ! part of collagenous component of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI @@ -5383,6 +5414,21 @@ xref: GC_ID:1 is_a: NCBITaxon:117570 ! Teleostomi property_value: skos:prefLabel "Euteleostomi" xsd:string +[Term] +id: NCBITaxon:119089 +name: Chromadorea +namespace: ncbi_taxonomy +synonym: "Adenophorea" RELATED synonym [] +xref: GC_ID:1 +is_a: NCBITaxon:6231 ! Nematoda + +[Term] +id: NCBITaxon:1206794 +name: Ecdysozoa +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:33317 ! Protostomia + [Term] id: NCBITaxon:131567 name: cellular organisms @@ -5475,6 +5521,20 @@ xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2759 ! Eukaryota +[Term] +id: NCBITaxon:2301116 +name: Rhabditina +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:6236 ! Rhabditida + +[Term] +id: NCBITaxon:2301119 +name: Rhabditomorpha +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:2301116 ! Rhabditina + [Term] id: NCBITaxon:2759 name: Eukaryota @@ -5491,6 +5551,22 @@ xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: skos:prefLabel "Eukaryota" xsd:string +[Term] +id: NCBITaxon:28009 +name: Choanoflagellata +namespace: ncbi_taxonomy +synonym: "Choanoflagellatea" RELATED synonym [] +synonym: "choanoflagellates" EXACT genbank_common_name [] +synonym: "choanoflagellates" RELATED blast_name [] +synonym: "Choanoflagellida" RELATED synonym [] +synonym: "Choanomonada" RELATED synonym [] +synonym: "Choanozoa" RELATED synonym [] +xref: GC_ID:1 +xref: PMID:27765632 +is_a: NCBITaxon:33154 ! Opisthokonta +disjoint_from: NCBITaxon:33208 ! Metazoa +disjoint_from: NCBITaxon:4751 ! Fungi + [Term] id: NCBITaxon:314146 name: Euarchontoglires @@ -5575,6 +5651,14 @@ xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa property_value: skos:prefLabel "Bilateria" xsd:string +[Term] +id: NCBITaxon:33317 +name: Protostomia +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:33213 ! Bilateria +disjoint_from: NCBITaxon:33511 ! Deuterostomia + [Term] id: NCBITaxon:33511 name: Deuterostomia @@ -5694,6 +5778,20 @@ xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota +[Term] +id: NCBITaxon:55879 +name: Rhabditoidea +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:2301119 ! Rhabditomorpha + +[Term] +id: NCBITaxon:55885 +name: Peloderinae +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:6243 ! Rhabditidae + [Term] id: NCBITaxon:6072 name: Eumetazoa @@ -5702,6 +5800,41 @@ xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: skos:prefLabel "Eumetazoa" xsd:string +[Term] +id: NCBITaxon:6231 +name: Nematoda +namespace: ncbi_taxonomy +synonym: "Nemata" RELATED synonym [] +synonym: "nematode" EXACT OMO:0003003 [] +synonym: "nematodes" EXACT genbank_common_name [] +synonym: "nematodes" RELATED blast_name [] +synonym: "roundworm" EXACT OMO:0003003 [] +synonym: "roundworms" EXACT OMO:0003003 [] +xref: GC_ID:1 +is_a: NCBITaxon:1206794 ! Ecdysozoa + +[Term] +id: NCBITaxon:6236 +name: Rhabditida +namespace: ncbi_taxonomy +synonym: "Strongylida" RELATED synonym [] +xref: GC_ID:1 +is_a: NCBITaxon:119089 ! Chromadorea + +[Term] +id: NCBITaxon:6237 +name: Caenorhabditis +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:55885 ! Peloderinae + +[Term] +id: NCBITaxon:6243 +name: Rhabditidae +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:55879 ! Rhabditoidea + [Term] id: NCBITaxon:7711 name: Chordata @@ -5976,6 +6109,14 @@ subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality +[Term] +id: PATO:0001591 +name: curvature +namespace: quality +def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] +subset: attribute_slim +is_a: PATO:0000052 ! shape + [Term] id: PATO:0001690 name: contractile @@ -6131,6 +6272,18 @@ is_a: PATO:0001018 ! physical quality property_value: terms:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-03-15T04:35:27Z +[Term] +id: PATO:0002254 +name: flattened +namespace: quality +def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] +comment: Becoming flat but not necessarily completely flat. +subset: value_slim +synonym: "compressed" RELATED [] +is_a: PATO:0001591 ! curvature +property_value: terms:contributor https://orcid.org/0000-0002-2061-091X +creation_date: 2010-08-16T03:59:34Z + [Term] id: PATO:0002266 name: 3-D shape @@ -12001,7 +12154,7 @@ xref: NCIT:C32339 xref: NIF_Subcellular:sao7547390221 is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: RO:0002473 GO:0005581 ! composed primarily of collagen trimer -relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen +relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen complex property_value: seeAlso UBERON:0007377 property_value: skos:prefLabel "collection of collagen fibrils" xsd:string diff --git a/src/ontology/subsets/general_cell_types_upper_slim.owl b/src/ontology/subsets/general_cell_types_upper_slim.owl index e4b044fa4..566357716 100644 --- a/src/ontology/subsets/general_cell_types_upper_slim.owl +++ b/src/ontology/subsets/general_cell_types_upper_slim.owl @@ -14,8 +14,8 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - - 2025-12-17 + + 2026-03-17 @@ -245,7 +245,6 @@ WHERE { An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has narrow synonym - has_narrow_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/19 @@ -2481,14 +2480,7 @@ Each of these 3 primitives can be composed to yield a cross-product of different - - - - - - - @@ -2505,13 +2497,12 @@ Stem cells have numerous potential applications in medicine, including the treat CALOHA:TS-2086 FMA:63368 ZFA:0005957 - animal stem cell + animal stem cell - This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. stem cell https://cellxgene.cziscience.com/cellguide/CL_0000034 stem cell @@ -2618,6 +2609,7 @@ Stem cells have numerous potential applications in medicine, including the treat + @@ -3413,7 +3405,26 @@ Blood vessel endothelial cells are sensitive to various stimuli, including shear + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -3962,6 +3973,7 @@ In addition to melanin production, melanocytes also engage in a variety of other A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -3975,6 +3987,7 @@ In addition to melanin production, melanocytes also engage in a variety of other + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -4473,6 +4486,7 @@ In addition to their role in oxygen transport, erythrocytes also play a key role + @@ -4817,6 +4831,7 @@ Clinically and in research, stromal cells often draw attention due to their inte + @@ -5940,6 +5955,7 @@ Apart from platelet production, megakaryocytes are involved in several other fun + @@ -7241,6 +7257,7 @@ The balance between cell proliferation and differentiation in embryonic cells is + @@ -7431,7 +7448,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -7613,6 +7629,7 @@ Disorders or aberrations in the development or migration of the neural crest cel Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. https://github.com/geneontology/go-ontology/issues/22192 https://github.com/geneontology/go-ontology/issues/25493 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.12 MetaCyc:PEPTIDYLTRANSFERASE-RXN Reactome:R-HSA-156912 @@ -8500,6 +8517,7 @@ Disorders or aberrations in the development or migration of the neural crest cel A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. + This is the same as GO molecular function molecular function molecular_function GO:0003674 @@ -8562,6 +8580,15 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + @@ -8681,10 +8708,16 @@ Disorders or aberrations in the development or migration of the neural crest cel - + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component @@ -10469,6 +10502,12 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. https://github.com/geneontology/go-ontology/issues/24968 2012-09-19T15:05:24Z @@ -10657,6 +10696,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. @@ -10705,6 +10768,16 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + @@ -10775,6 +10848,16 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + @@ -10845,6 +10928,16 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + @@ -10881,6 +10974,70 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. @@ -11535,10 +11692,10 @@ Disorders or aberrations in the development or migration of the neural crest cel Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + https://github.com/geneontology/go-ontology/issues/30193 EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 - Reactome:R-HSA-5333607 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function @@ -11573,12 +11730,6 @@ Disorders or aberrations in the development or migration of the neural crest cel Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 - - - - Reactome:R-HSA-5333607 - GSSeH combines with bGalNAc derivative to form GSSebGalNac - @@ -11600,6 +11751,7 @@ Disorders or aberrations in the development or migration of the neural crest cel Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 @@ -11650,6 +11802,7 @@ Disorders or aberrations in the development or migration of the neural crest cel Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function @@ -12226,12 +12379,14 @@ Disorders or aberrations in the development or migration of the neural crest cel A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 https://github.com/geneontology/go-ontology/issues/26279 cell projection organisation biological_process cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 + cell projection organization @@ -12281,10 +12436,12 @@ Disorders or aberrations in the development or migration of the neural crest cel Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 formation of a cell surface projection biological_process cell projection biogenesis GO:0030031 + cell projection assembly @@ -13133,6 +13290,7 @@ Disorders or aberrations in the development or migration of the neural crest cel A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + This is not covalently bonded, which conflicts with changes to the parent definition. macromolecular complex macromolecule complex protein containing complex @@ -13512,13 +13670,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. + Wikipedia:Melanosome cellular_component GO:0042470 @@ -13538,7 +13713,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - Any biological process involved in the maintenance of an internal steady state. + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + https://github.com/geneontology/go-ontology/issues/31175 homeostasis activation of homeostatic process inhibition of homeostatic process @@ -13555,9 +13731,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - Any biological process involved in the maintenance of an internal steady state. - GOC:jl - ISBN:0395825172 + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + PMID:26265027 @@ -13665,6 +13840,16 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + @@ -13773,11 +13958,13 @@ Disorders or aberrations in the development or migration of the neural crest cel A prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 cell process cellular process cellular projection cellular_component GO:0042995 + @@ -16382,9 +16569,10 @@ Disorders or aberrations in the development or migration of the neural crest cel https://github.com/geneontology/go-ontology/issues/29474 https://github.com/geneontology/go-ontology/issues/30146 banded collagen fibril + fibrillar collagen cellular_component GO:0098643 - fibrillar collagen + fibrillar collagen complex fibrillar collagen @@ -16449,9 +16637,11 @@ Disorders or aberrations in the development or migration of the neural crest cel A supramolecular complex that consists of collagen triple helices associated to form a network. + https://github.com/geneontology/go-ontology/issues/30938 + collagen network cellular_component GO:0098645 - collagen network + complex of network-forming collagens @@ -16665,6 +16855,9 @@ Disorders or aberrations in the development or migration of the neural crest cel A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes. + Overlaps with some cellular components from GO https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 https://github.com/geneontology/go-ontology/issues/28978 @@ -17458,6 +17651,37 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + GC_ID:1 + ncbi_taxonomy + Adenophorea + NCBITaxon:119089 + Chromadorea + + + + + Adenophorea + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:1206794 + Ecdysozoa + + + + @@ -17682,6 +17906,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:2301116 + Rhabditina + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:2301119 + Rhabditomorpha + + + + @@ -17739,6 +17987,63 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + GC_ID:1 + PMID:27765632 + choanoflagellates + ncbi_taxonomy + Choanoflagellatea + Choanoflagellida + Choanomonada + Choanozoa + choanoflagellates + NCBITaxon:28009 + Choanoflagellata + + + + + choanoflagellates + + + + + + Choanoflagellatea + + + + + + Choanoflagellida + + + + + + Choanomonada + + + + + + Choanozoa + + + + + + choanoflagellates + + + + + @@ -17929,6 +18234,19 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:33317 + Protostomia + + + + @@ -18185,6 +18503,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:55879 + Rhabditoidea + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:55885 + Peloderinae + + + + @@ -18198,6 +18540,103 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + GC_ID:1 + nematode + nematodes + roundworm + roundworms + ncbi_taxonomy + Nemata + nematodes + NCBITaxon:6231 + Nematoda + + + + + nematode + + + + + + nematodes + + + + + + roundworm + + + + + + roundworms + + + + + + Nemata + + + + + + nematodes + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + Strongylida + NCBITaxon:6236 + Rhabditida + + + + + Strongylida + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:6237 + Caenorhabditis + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:6243 + Rhabditidae + + + + @@ -18829,6 +19268,25 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + quality + PATO:0001591 + + curvature + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + WordNet:WordNet + + + + @@ -19170,6 +19628,29 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + + 2010-08-16T03:59:34Z + quality + compressed + PATO:0002254 + + Becoming flat but not necessarily completely flat. + flattened + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + PATOC:CVS + + + + @@ -21588,7 +22069,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -21599,14 +22080,14 @@ Disorders or aberrations in the development or migration of the neural crest cel membrane organ membrane organ - + - + FMA-def @@ -22375,7 +22856,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -22417,14 +22898,14 @@ Disorders or aberrations in the development or migration of the neural crest cel gastrula stage gastrula stage - + - + BILS @@ -22909,15 +23390,15 @@ Disorders or aberrations in the development or migration of the neural crest cel - + - - + + A fluid that is composed of blood plasma and erythrocytes. @@ -22956,34 +23437,34 @@ Disorders or aberrations in the development or migration of the neural crest cel blood blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -24795,7 +25276,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. AAO:0000137 BILA:0000036 @@ -24830,14 +25311,14 @@ Disorders or aberrations in the development or migration of the neural crest cel ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -24877,7 +25358,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. AAO:0000139 BILA:0000038 @@ -24912,14 +25393,14 @@ Disorders or aberrations in the development or migration of the neural crest cel http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -24960,7 +25441,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The middle germ layer of the embryo, between the endoderm and ectoderm. AAO:0000304 @@ -25000,14 +25481,14 @@ Disorders or aberrations in the development or migration of the neural crest cel mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + - + Bgee:AN @@ -25175,7 +25656,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -25240,14 +25721,14 @@ Disorders or aberrations in the development or migration of the neural crest cel https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb - + - + MA @@ -25659,7 +26140,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -25709,14 +26190,14 @@ Disorders or aberrations in the development or migration of the neural crest cel http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -25776,7 +26257,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. @@ -25821,7 +26302,7 @@ Disorders or aberrations in the development or migration of the neural crest cel central nervous system central nervous system - + @@ -25835,7 +26316,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Bgee:AN @@ -26206,7 +26687,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -26231,14 +26712,14 @@ Disorders or aberrations in the development or migration of the neural crest cel mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -26370,13 +26851,13 @@ Disorders or aberrations in the development or migration of the neural crest cel - + - + Skeletal element that is composed of bone tissue. @@ -26418,14 +26899,14 @@ Disorders or aberrations in the development or migration of the neural crest cel bone element bone element - + - + VSAO-modified @@ -26579,7 +27060,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + A tube extending from the mouth to the anus. @@ -26617,14 +27098,14 @@ Disorders or aberrations in the development or migration of the neural crest cel digestive tract digestive tract - + - + NCBIBook:NBK10107 @@ -27182,8 +27663,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + @@ -27196,7 +27677,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -27250,34 +27731,34 @@ Disorders or aberrations in the development or migration of the neural crest cel blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -28149,7 +28630,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -28185,14 +28666,14 @@ Disorders or aberrations in the development or migration of the neural crest cel coelemic cavity lumen coelemic cavity lumen - + - + definitional @@ -28288,8 +28769,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + @@ -28339,11 +28820,11 @@ Disorders or aberrations in the development or migration of the neural crest cel notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -28362,13 +28843,13 @@ Disorders or aberrations in the development or migration of the neural crest cel - + ZFA - + EHDAA2 @@ -28409,7 +28890,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. mesodermal cluster @@ -28447,7 +28928,7 @@ Disorders or aberrations in the development or migration of the neural crest cel somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -28460,7 +28941,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + ZFA @@ -28578,16 +29059,16 @@ Disorders or aberrations in the development or migration of the neural crest cel - - - + + + - + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. AAO:0010578 BTO:0001764 @@ -28620,45 +29101,45 @@ Disorders or aberrations in the development or migration of the neural crest cel http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + BTO - + PMID:11523831 - + PMID:11523831 @@ -29018,8 +29499,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + Anatomical system that is involved in the production of hematopoietic cells. AAO:0011002 @@ -29059,24 +29540,24 @@ Disorders or aberrations in the development or migration of the neural crest cel hematopoietic system hematopoietic system - + - + - + FMA - + definitional @@ -29397,7 +29878,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -29416,7 +29897,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. AAO:0011086 EFO:0001982 @@ -29439,14 +29920,14 @@ Disorders or aberrations in the development or migration of the neural crest cel presomitic mesoderm presomitic mesoderm - + - + Bgee:AN @@ -29602,8 +30083,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. AAO:0011072 BTO:0001765 @@ -29632,24 +30113,24 @@ Disorders or aberrations in the development or migration of the neural crest cel neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + Wikipedia - + Bgee:AN @@ -29695,7 +30176,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. AAO:0010568 EFO:0003515 @@ -29721,7 +30202,7 @@ Disorders or aberrations in the development or migration of the neural crest cel paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -29734,7 +30215,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Bgee:AN @@ -29781,7 +30262,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -29820,7 +30301,7 @@ Disorders or aberrations in the development or migration of the neural crest cel lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -29833,7 +30314,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + EHDAA2 VHOG @@ -29884,15 +30365,15 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. AAO:0011044 @@ -29909,15 +30390,15 @@ Disorders or aberrations in the development or migration of the neural crest cel heart primordium heart primordium - + - + - + @@ -29930,19 +30411,19 @@ Disorders or aberrations in the development or migration of the neural crest cel - + ZFA - + ZFA - + XAO @@ -29971,8 +30452,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. AAO:0010571 AEO:0000212 @@ -29996,11 +30477,11 @@ Disorders or aberrations in the development or migration of the neural crest cel sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -30019,13 +30500,13 @@ Disorders or aberrations in the development or migration of the neural crest cel - + VHOG:0000680 - + ZFA @@ -30278,7 +30759,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults EHDAA:251 @@ -30293,14 +30774,14 @@ Disorders or aberrations in the development or migration of the neural crest cel intraembryonic coelom intraembryonic coelom - + - + Wikipedia @@ -30658,8 +31139,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. XAO:0004185 first heart field @@ -30671,24 +31152,24 @@ Disorders or aberrations in the development or migration of the neural crest cel primary heart field primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -30741,7 +31222,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + An epithelial tube that will give rise to the mature heart. AAO:0010411 EFO:0003526 @@ -30760,14 +31241,14 @@ Disorders or aberrations in the development or migration of the neural crest cel heart tube heart tube - + - + ZFA-modified @@ -31482,7 +31963,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. AAO:0011129 TAO:0001890 @@ -31496,14 +31977,14 @@ Disorders or aberrations in the development or migration of the neural crest cel skeletal element skeletal element - + - + VSAO @@ -31531,7 +32012,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -31564,14 +32045,14 @@ Disorders or aberrations in the development or migration of the neural crest cel articular system articular system - + - + FMA @@ -32269,7 +32750,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -32285,14 +32766,14 @@ Disorders or aberrations in the development or migration of the neural crest cel trunk mesenchyme trunk mesenchyme - + - + EHDAA2 @@ -32410,7 +32891,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. EHDAA2:0001512 EHDAA:424 @@ -32428,14 +32909,14 @@ Disorders or aberrations in the development or migration of the neural crest cel primitive heart tube primitive heart tube - + - + ZFA @@ -32595,7 +33076,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -32605,7 +33086,7 @@ Disorders or aberrations in the development or migration of the neural crest cel developing mesenchymal condensation developing mesenchymal condensation - + @@ -32624,7 +33105,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + AEO-modified-relation @@ -32720,7 +33201,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB EHDAA2:0001278 @@ -32734,7 +33215,7 @@ Disorders or aberrations in the development or migration of the neural crest cel notochordal plate notochordal plate - + @@ -32747,7 +33228,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + EHDAA2 @@ -32776,7 +33257,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -32793,14 +33274,14 @@ Disorders or aberrations in the development or migration of the neural crest cel notochordal process notochordal process - + - + EHDAA2 @@ -33674,7 +34155,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -33700,7 +34181,7 @@ Disorders or aberrations in the development or migration of the neural crest cel presumptive paraxial mesoderm presumptive paraxial mesoderm - + @@ -33716,7 +34197,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + https://github.com/obophenotype/uberon/issues/1277 @@ -33793,7 +34274,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -33801,7 +34282,7 @@ Disorders or aberrations in the development or migration of the neural crest cel dense mesenchyme tissue dense mesenchyme tissue - + @@ -33814,7 +34295,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + AEO @@ -33880,7 +34361,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -33900,14 +34381,14 @@ Disorders or aberrations in the development or migration of the neural crest cel layer of synovial tissue layer of synovial tissue - + - + BTO @@ -34181,7 +34662,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -34198,14 +34679,14 @@ Disorders or aberrations in the development or migration of the neural crest cel vascular system vascular system - + - + MA @@ -34235,7 +34716,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -34251,14 +34732,14 @@ Disorders or aberrations in the development or migration of the neural crest cel entire embryonic mesenchyme entire embryonic mesenchyme - + - + EHDAA2 @@ -34314,7 +34795,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme @@ -34322,14 +34803,14 @@ Disorders or aberrations in the development or migration of the neural crest cel trunk paraxial mesoderm trunk paraxial mesoderm - + - + EHDAA2 @@ -34424,7 +34905,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -34434,14 +34915,14 @@ Disorders or aberrations in the development or migration of the neural crest cel anterior lateral plate mesoderm anterior lateral plate mesoderm - + - + ZFA @@ -34639,7 +35120,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -34649,14 +35130,14 @@ Disorders or aberrations in the development or migration of the neural crest cel microcirculatory vessel microcirculatory vessel - + - + ZFA @@ -34681,8 +35162,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. FMA:23879 SCTID:129140006 @@ -34694,11 +35175,11 @@ Disorders or aberrations in the development or migration of the neural crest cel subdivision of skeleton subdivision of skeleton - + - + @@ -34711,13 +35192,13 @@ Disorders or aberrations in the development or migration of the neural crest cel - + UBERONREF:0000003 - + VSAO @@ -34811,7 +35292,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -34822,7 +35303,7 @@ Disorders or aberrations in the development or migration of the neural crest cel http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton postcranial axial skeletal system - + @@ -34835,7 +35316,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + cjm @@ -35788,7 +36269,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -35811,7 +36292,7 @@ Disorders or aberrations in the development or migration of the neural crest cel entire extraembryonic component entire extraembryonic component - + @@ -35824,7 +36305,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + AEO @@ -36332,14 +36813,14 @@ Disorders or aberrations in the development or migration of the neural crest cel - + - + definitional - + @@ -36527,6 +37008,34 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -36621,6 +37130,34 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -36635,6 +37172,40 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -36767,6 +37338,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + @@ -36949,6 +37544,34 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -36963,6 +37586,62 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/src/ontology/subsets/general_cell_types_upper_slim.tsv b/src/ontology/subsets/general_cell_types_upper_slim.tsv index f68d1585f..41ecc759a 100644 --- a/src/ontology/subsets/general_cell_types_upper_slim.tsv +++ b/src/ontology/subsets/general_cell_types_upper_slim.tsv @@ -312,9 +312,9 @@ http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer -http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen +http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers -http://purl.obolibrary.org/obo/GO_0098645 collagen network +http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling @@ -347,13 +347,18 @@ http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_10090 Mus musculus http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi +http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea +http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria +http://purl.obolibrary.org/obo/NCBITaxon_2301116 Rhabditina +http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota +http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda @@ -362,6 +367,7 @@ http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria +http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_34346 Schizosaccharomycetales @@ -375,7 +381,13 @@ http://purl.obolibrary.org/obo/NCBITaxon_4894 Schizosaccharomycetaceae http://purl.obolibrary.org/obo/NCBITaxon_4895 Schizosaccharomyces http://purl.obolibrary.org/obo/NCBITaxon_4896 Schizosaccharomyces pombe http://purl.obolibrary.org/obo/NCBITaxon_554915 Amoebozoa +http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea +http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa +http://purl.obolibrary.org/obo/NCBITaxon_6231 Nematoda +http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida +http://purl.obolibrary.org/obo/NCBITaxon_6237 Caenorhabditis +http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata @@ -403,6 +415,7 @@ http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0001579 contractility +http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0001873 cylindrical @@ -419,6 +432,7 @@ http://purl.obolibrary.org/obo/PATO_0002045 dendritic http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance +http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002318 superelliptic diff --git a/src/ontology/subsets/kidney_upper_slim.json b/src/ontology/subsets/kidney_upper_slim.json index 4f9e8e922..1ad1a6ba4 100644 --- a/src/ontology/subsets/kidney_upper_slim.json +++ b/src/ontology/subsets/kidney_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2025-12-17" + "val" : "2026-03-17" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2025-12-17/subsets/kidney_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2026-03-17/subsets/kidney_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -43,7 +43,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { - "val" : "FBbt:00007002" + "val" : "FBbt:00007002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:68646" }, { @@ -59,7 +65,13 @@ }, { "val" : "XAO:0003012" }, { - "val" : "ZFA:0009000" + "val" : "ZFA:0009000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -77,7 +89,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009002" + "val" : "ZFA:0009002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -93,10 +111,9 @@ "val" : "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, - "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { - "pred" : "hasExactSynonym", + "pred" : "hasNarrowSynonym", "val" : "animal stem cell" } ], "xrefs" : [ { @@ -104,7 +121,13 @@ }, { "val" : "FMA:63368" }, { - "val" : "ZFA:0005957" + "val" : "ZFA:0005957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -114,7 +137,13 @@ "val" : "Stem cells are a unique type of cell that has the remarkable ability to divide and develop into many different types of cells in the body. These cells are undifferentiated, meaning they haven't yet developed into a specific cell type, and they can renew themselves through cell division. As a result, stem cells have the potential to replace damaged or diseased cells in the body, making them a valuable tool in medicine and research.\nThere are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos and can develop into any type of cell in the body. Adult stem cells, on the other hand, are found in various tissues and organs throughout the body and can only develop into certain types of cells.\nStem cells have numerous potential applications in medicine, including the treatment of various diseases and the repair of damaged tissues. For example, they could be used to replace damaged heart tissue after a heart attack or to repair spinal cord injuries. Stem cells also have potential uses in drug development and disease research, as they can be used to model diseases and test potential therapies in vitro.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stem cell" @@ -156,7 +185,13 @@ }, { "val" : "VHOG:0001485" }, { - "val" : "ZFA:0009014" + "val" : "ZFA:0009014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -166,7 +201,13 @@ "val" : "Hematopoietic stem cells (HSCs) are multipotent cells, capable of differentiating into a wide variety of specialized blood cells. During embryonic development hematopoietic stem cells emerge from the hemogenic endothelium, a specialized subset of endothelial cells with hematopoietic potential. HSCs can be found in several organs, in particular in bone marrow, as well as peripheral blood and umbilical cord blood.\nThese stem cells have a distinctive ability to self-renew, and to differentiate into all lymphoid and myeloid cell types that together form the blood and immune systems including erythrocytes (red blood cells), leukocytes (white blood cells), and platelets. Their primary function is to ensure the continuous replenishment of the blood and immune system throughout an individual's lifespan.\nIn response to various signals, hematopoietic stem cells can either remain dormant or actively divide and differentiate. Under normal conditions, the majority of these stem cells exist in a quiescent (inactive) state, making them somewhat resistant to chemotherapy or radiation therapy in the treatment of various diseases such as leukemia. However, when the body encounters stress such as infection, bleeding, or disease, hematopoietic stem cells can rapidly become active in order to replenish the affected cells and maintain homeostasis.\nFurthermore, hematopoietic stem cells are extremely important in the field of regenerative medicine and transplantation. Regarded as lifesaving in the field of oncology, they are often extracted, purified, and reinfused back into the same (autologous transplantation) or different (allogeneic transplantation) individuals to reestablish a healthy, functioning hematopoietic and immune system after high-dose chemotherapy or to replace dysfunctional bone marrow. Understanding and manipulating the behavior of these stem cells has immense potential in treating various blood disorders, autoimmune diseases, and cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "hematopoietic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "hematopoietic stem cell" @@ -206,14 +247,26 @@ "xrefs" : [ { "val" : "BTO:0004911" }, { - "val" : "ZFA:0009015" + "val" : "ZFA:0009015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Erythroid progenitor cells play a key role in the hematopoietic system, specifically in the process of erythropoiesis – the production of red blood cells (erythrocytes). Found within the bone marrow, these cells are dedicated precursors to erythrocytes, and ensue in the hematopoietic lineage from multipotent progenitors. They represent a transitional cell type that bridges the gap between the early-stage erythroid precursors and the maturing red blood cell population.\nThe earliest committed erythroid progenitor cell is thought to be the burst-forming unit-erythroid (BFU-E) cell, which after several cell divisions gives rise to another erythroid progenitor, the colony-forming unit-erythroid (CFU-E) cell. \nErythroid progenitor cells are primarily responsible for responding to the demand for new red blood cells during conditions of physiological stress like infection, blood loss, or illness. This responsive behavior is regulated by a glycoprotein hormone known as erythropoietin, which is produced by the kidneys. Erythropoietin interacts with the receptors on the erythroid progenitor cells, prompting them to proliferate and differentiate into erythroblasts. The erythroblasts then further mature, eventually producing new, functional red cells.\nThe role of erythroid progenitor cells extends beyond their main function of erythrocyte production, as they also participate in maintaining the balance of iron in the body. Upon erythroid differentiation, they increase their uptake of transferrin-bound iron for hemoglobin synthesis, a vital component of red blood cells which allows them to transport oxygen. A deficiency or excess of erythroid progenitor cells can lead to extensive health issues such as anemia or polycythemia respectively, emphasizing their crucial role in human health.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythroid progenitor cell" @@ -231,7 +284,13 @@ "comments" : [ "Originally this term had some plant germ line cell children." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { - "val" : "ZFA:0009016" + "val" : "ZFA:0009016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -264,7 +323,13 @@ "xrefs" : [ { "val" : "FMA:84789" }, { - "val" : "ZFA:0009020" + "val" : "ZFA:0009020", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -320,7 +385,13 @@ "xrefs" : [ { "val" : "BTO:0004730" }, { - "val" : "ZFA:0009021" + "val" : "ZFA:0009021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -330,7 +401,13 @@ "val" : "The common myeloid progenitor (CMP) is a multipotent cell that serves as a crucial intermediary within the overall framework of hematopoietic cell differentiation, which is the process of blood cell production. This part of the hematopoiesis process leads to the formation of myeloid lineage cells, which includes granulocytes (neutrophils, eosinophils, and basophils), monocytes, erythrocytes (red blood cells), and megakaryocytes (platelet-forming cells). \nThe primary function of common myeloid progenitors is differentiation and proliferation into various types of mature blood cells, thereby providing a critical contribution to maintaining homeostasis within the body's immune and circulatory systems. Single-cell analyses have shown that the CMP cell population is heterogeneous with at least two distinct subpopulations, characterized by different cell surface markers and likely already committed to downstream differentiation into either the granulocyte/macrophage lineage or the megakaryocyte/erythrocyte lineage-restricted progenitor. \nThe destiny of a CMP is influenced by numerous cytokines and growth factors in its environment that promote differentiation along specific lineages. For example, IL-3 and GM-CSF stimulate the production of eosinophils, which are essential for the body’s defense against allergens and help fight fungal and parasitic infections. \nBy being able to differentiate into a wide range of different immune cells, common myeloid progenitors play a crucial role in the body's ability to respond to injuries, infections, and other physiological challenges.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "common myeloid progenitor on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "common myeloid progenitor" @@ -370,7 +447,13 @@ "val" : "megakaryocyte/erythroid progenitor cell" } ], "xrefs" : [ { - "val" : "ZFA:0009022" + "val" : "ZFA:0009022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -380,7 +463,13 @@ "val" : "The megakaryocyte-erythroid progenitor (MEP) cell belongs to the multipotent hematopoietic progenitor cells, which can give rise to multiple different cell types. They are found in the bone marrow, the primary organ where new blood cells are generated. MEPs are specially programmed to develop into two distinct blood cell lineages, namely megakaryocytes, which go on to produce platelets for blood clotting, and the erythroid lineage which consists of red blood cells responsible for oxygen transport in the body.\nThe MEP cells are the result of a decision-making process within the hematopoietic stem cell population. Hematopoietic stem cell can differentiate into multiple types of progenitor cells, including myeloid progenitor cells. A further subdivision within this myeloid lineage generates the MEP cells. Therefore, these megakaryocyte-erythroid progenitors represent a key juncture between hematopoietic stem cells and mature blood cell types in the myeloid lineage.\nMegakaryocyte-erythroid progenitor cells play a crucial role in the homeostasis of some of the most crucial constituents of blood. The megakaryocytes produced from these bipotent progenitor cells contribute to hemostasis by producing platelets - small anucleated fragments that are pivotal for blood clotting and preventing bleeding. Similarly, the erythroid lineage from MEP cells gives rise to erythrocytes, which harbor hemoglobin, the molecule that transports oxygen from lungs to every nook and corner of the body. An imbalance or malfunction in MEP function thus can significantly impact human health, leading to diseases like thrombocytopenia or anemia.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte-erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "megakaryocyte-erythroid progenitor cell" @@ -405,7 +494,13 @@ }, { "val" : "MESH:D039901" }, { - "val" : "ZFA:0009024" + "val" : "ZFA:0009024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -427,13 +522,25 @@ }, { "val" : "CALOHA:TS-0650" }, { - "val" : "FBbt:00005083" + "val" : "FBbt:00005083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:70335" }, { "val" : "VHOG:0001529" }, { - "val" : "ZFA:0009025" + "val" : "ZFA:0009025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -462,7 +569,13 @@ }, { "val" : "VHOG:0001482" }, { - "val" : "ZFA:0009026" + "val" : "ZFA:0009026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -493,13 +606,25 @@ }, { "val" : "CARO:0000077" }, { - "val" : "FBbt:00000124" + "val" : "FBbt:00000124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:66768" }, { "val" : "WBbt:0003672" }, { - "val" : "ZFA:0009034" + "val" : "ZFA:0009034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -523,14 +648,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009372" + "val" : "ZFA:0009372", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Duct epithelial cells are distinctly specialized cells that predominantly form the lining of glandular ducts. These cells play a crucial role in the secretion, absorption, and transport of fluids depending on the organ they inhabit. They are typically organized in a tubular structure, forming collectively the conduit for the transport of substances. These cells exhibit tight junctions, enabling the careful regulation of the passage of substances and ensuring that no unwanted particles seep through. They are predominantly characterized by their polarized nature, having distinct apical and basolateral surfaces that support its functions of secretion and absorption. The apical surface, exposed to the duct lumen, is specialized for secretion and interaction with the luminal environment, while the basolateral surface is oriented towards the underlying tissue, facilitating interactions with neighboring cells and the extracellular matrix.\nThe ducts serve as the bridge between the gland and the site of secretion, allowing the substances produced by the gland to exit into the body. Thus, duct epithelial cells have a sweeping role in various physiological functions, ranging from defense against pathogens in the respiratory and digestive tracts, to secretion of digestive enzymes, to milk production in mammary glands.\nAs a result of their specialized function, any impairment in the function of duct epithelial cells to function properly often leads to certain diseases or disorders. Studies have identified potential correlation between malfunctioning duct epithelial cells and conditions such as cystic fibrosis, chronic obstructive pulmonary disease, and certain cancers, particularly breast and pancreatic.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000068" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000068", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "duct epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -544,7 +681,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009036" + "val" : "ZFA:0009036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -554,7 +697,13 @@ "val" : "Blood vessel endothelial cells, also known as vascular endothelial cells, form the delicate inner lining of the complex circulatory system, including arteries and veins. These cells form a single, continuous monolayer inside every blood vessel, acting as a crucial biomolecular barrier between the blood, and the rest of the body tissues. They perform various fundamental biological functions, ranging from maintenance of vessel integrity to blood clotting regulation. Additionally, they control the transportation of fluids, molecules, and blood particulate matter from and into the bloodstream.\nOne of the primary functions of blood vessel endothelial cells is to maintain vascular homeostasis - a stable environment within the blood vessels. They accomplish this through several methods: they control vasomotor tone, i.e. the degree of contraction and dilation of blood vessels, by secreting vasoactive substances such as nitric oxide and endothelin; mediate responses to inflammatory stimuli; and they also regulate angiogenesis, the process of new blood vessel formations. Blood vessel endothelial cells play a significant role in preventing blood clot formation by generating a slick, non-thrombogenic surface that disallows platelets or coagulant proteins from adhering to it.\nBlood vessel endothelial cells are sensitive to various stimuli, including shear stress caused by blood flow, and they can respond by altering their morphology, function, and gene expression. This ability to adapt enables blood vessels to remodel and ensure the adequate delivery of nutrients and oxygen to all tissues, regardless of physiological demand variations. Conversely, endothelial dysfunction, often associated with a reduction in the bioavailability of endothelium-derived nitric oxide, can lead to the development of pathological conditions such as atherosclerosis, hypertension, diabetes mellitus, and even aging-related diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "blood vessel endothelial cell" @@ -578,7 +727,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009038" + "val" : "ZFA:0009038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -593,13 +748,25 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "definition" : { + "val" : "An epithelial cell that has a flattened morphology." + }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" }, { - "val" : "ZFA:0009039" + "val" : "ZFA:0009039", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/date", + "val" : "2025-12-16T15:56:39Z" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "squamous epithelial cell" } ] @@ -622,7 +789,13 @@ "xrefs" : [ { "val" : "FMA:66773" }, { - "val" : "ZFA:0009040" + "val" : "ZFA:0009040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -632,7 +805,13 @@ "val" : "Mesothelial cells are crucial components of the mesothelium, a protective layer that lines the body's internal cavities, including pleural cavity (around the lungs), the pericardial cavity (around the heart), and the peritoneal cavity (within the abdomen). Derived from the embryonic mesoderm layer, these cells exhibit a squamous-like epithelial morphology, usually appearing as a single layer of flat, pavement-like cells in their healthy state.\nMesothelial cells play a vital role in various physiological processes, such as intraperitoneal immunity, fibrinolysis, tissue repair, and tumor suppression. Their primary function is to provide a slippery, non-adhesive and protective surface to reduce friction and eases the movements of the organs within the pleural, pericardial, and peritoneal cavities, and they participate in the transport and movement of fluid and various molecules across the so-called serosal cavities. \nThese cells have adaptive capabilities that facilitate their role in many pathological processes. In response to injury or inflammation, mesothelial cells can undergo morphological and functional changes, such as mesothelial-mesenchymal transitions, aiding in wound healing and tissue repair. Dysfunctions of mesothelial cells, however, can lead to serious health conditions, including adhesions, fibrosis, and malignancies such as peritoneal and pleural mesotheliomas.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -650,7 +829,13 @@ }, { "val" : "MESH:D001773" }, { - "val" : "ZFA:0009044" + "val" : "ZFA:0009044", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -679,7 +864,13 @@ }, { "val" : "FMA:66772" }, { - "val" : "ZFA:0009065" + "val" : "ZFA:0009065", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -704,7 +895,13 @@ "val" : "neurectoderm cell" } ], "xrefs" : [ { - "val" : "ZFA:0009080" + "val" : "ZFA:0009080", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -776,14 +973,26 @@ }, { "val" : "FMA:70546" }, { - "val" : "ZFA:0009081" + "val" : "ZFA:0009081", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. These cells originate mainly from the mesoderm of the embryo, which forms connective tissues, muscle, and the circulatory and urinary systems. However, in adults, MSCs are found in multiple tissues, including bone marrow, adipose tissue, the umbilical cord, and dental tissues. \nThe primary function of MSCs is to maintain and repair the tissues in which they are found. When damage occurs, the MSCs are able to migrate to the site of injury, where they aid in regenerating the damaged tissue by differentiating into the required cell type and by secreting growth factors that enhance tissue repair and reduce inflammation. Furthermore, MSCs can also act as immunomodulators, suppressing immune reactions and reducing inflammation, both locally and systemically.\nApart from their role in tissue maintenance and repair, MSCs are integral to the field of regenerative medicine and are being investigated for their therapeutic potential in various clinical settings. Owing to their multipotent nature, immunomodulatory activity, and the relative ease of isolation, these cells can be engineered and translated into therapies to treat a variety of diseases, including bone and cartilage defects, liver diseases, heart disorders, and autoimmune diseases, amongst others. They have also been used as vectors for anticancer agents and in cell and gene therapy applications.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val" : "https://github.com/obophenotype/cell-ontology/issues/474" @@ -858,7 +1067,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -873,15 +1082,30 @@ }, { "val" : "CALOHA:TS-2032" }, { - "val" : "FBbt:00005074" + "val" : "FBbt:00005074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67328" }, { "val" : "WBbt:0003675" }, { - "val" : "ZFA:0009114" + "val" : "ZFA:0009114", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle cell" }, { @@ -921,7 +1145,13 @@ }, { "val" : "FMA:14072" }, { - "val" : "ZFA:0009118" + "val" : "ZFA:0009118", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -931,7 +1161,13 @@ "val" : "Smooth muscle cells are a specialized type of muscle cells that are primarily found within the walls of hollow organs such as the intestine, stomach, bladder, uterus, and blood vessels. These cells are an essential component of the autonomic nervous system controling involuntary movements within the body.\nSmooth muscle cells play a vital role in many physiological processes due to their unique functionality. They can contract and relax in a slow, sustained, and controlled manner to help modulate the size and shape of the lumens of the organs they surround. For example, in the digestive system, coordinated contraction and relaxation of smooth muscle cells propels food along the gastrointestinal tract - a process known as peristalsis. In the blood vessels, the smooth muscle cells, by contracting or relaxing, either constrict or dilate the vessels, which in turn, help regulate blood flow and pressure.\nOn a cellular level, smooth muscle cells possess a single, centrally located nucleus and contain an arranged network of actin and myosin filaments, which are the proteins responsible for muscle contraction. Unlike their counterparts in skeletal or cardiac muscles, these cells lack specific contact points for these filaments, hence the lack of visible striations. Furthermore, the contraction of smooth muscle cells is regulated by hormones and neurotransmitters, such as acetylcholine and norepinephrine, adding an additional layer of complex regulation to these highly specialized cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000192" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000192", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "smooth muscle cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "smooth muscle cell" @@ -948,7 +1184,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009128" + "val" : "ZFA:0009128", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -971,7 +1213,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-0995" }, { - "val" : "ZFA:0009131" + "val" : "ZFA:0009131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -985,7 +1233,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009136" + "val" : "ZFA:0009136", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1009,7 +1263,13 @@ "xrefs" : [ { "val" : "FMA:72549" }, { - "val" : "ZFA:0009137" + "val" : "ZFA:0009137", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1036,14 +1296,26 @@ "xrefs" : [ { "val" : "FMA:72554" }, { - "val" : "ZFA:0009138" + "val" : "ZFA:0009138", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesodermal cells are pluripotent and the most abundant in the human body. They contribute to the development of several structures such as the skeletal muscles, bones, heart and blood vessels, kidneys, gonads, connective tissues, and certain layers of the skin. Hence, the mesoderm is often regarded as an active and diverse layer due to its role in forming many bodily structures. \nIn embryonic development, these cells are instrumental, contributing to the body's structures through a carefully coordinated sequence of morphogenetic movements. This process forms the complex multicellular architecture of tissues and organs from a simple ball of cells. Without the function of mesodermal cells, the body's integral structures and systems would cease to form correctly, leading to developmental disorders such as axial mesodermal dysplasia complex\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesodermal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesodermal cell" @@ -1066,7 +1338,13 @@ "xrefs" : [ { "val" : "FMA:72555" }, { - "val" : "ZFA:0009139" + "val" : "ZFA:0009139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1105,7 +1383,13 @@ "val" : "Erythrocytes, also known as red blood cells, are a type of specialized cell that make up the largest percentage of cells in the human body. Erythrocytes are biconcave in shape and lack nuclei and organelles, allowing them to carry oxygen and carbon dioxide through the bloodstream more efficiently. The main function of erythrocytes is to transport oxygen from the lungs to the body's tissues and organs, and to transport carbon dioxide from the body's tissues to the lungs, where it can be exhaled out of the body. Hemoglobin, a protein located inside erythrocytes, is responsible for binding to oxygen. \nErythrocytes are produced in the bone marrow and have a lifespan of approximately 120 days before they are broken down and recycled by the body. Erythrocytes are regulated by the hormone erythropoietin, which is produced by the kidneys and liver in response to low oxygen levels in the body, thereby stimulating erythrocyte production .\nIn addition to their role in oxygen transport, erythrocytes also play a key role in regulating the body's pH levels. Without erythrocytes, oxygen would not be able to be transported efficiently throughout the body and tissues would not receive the necessary oxygen to function properly. Overall, erythrocytes are essential for maintaining the health and homeostasis of the body.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythrocyte on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythrocyte" @@ -1160,7 +1444,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009164" + "val" : "ZFA:0009164", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1180,7 +1470,13 @@ "xrefs" : [ { "val" : "FMA:86667" }, { - "val" : "ZFA:0007086" + "val" : "ZFA:0007086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1198,7 +1494,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009166" + "val" : "ZFA:0009166", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1257,7 +1559,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009190" + "val" : "ZFA:0009190", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1275,7 +1583,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009193" + "val" : "ZFA:0009193", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1297,7 +1611,13 @@ }, { "val" : "FMA:83624" }, { - "val" : "ZFA:0009226" + "val" : "ZFA:0009226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1307,7 +1627,13 @@ "val" : "Stromal cells constitute a significant portion of the structural cellular milieu (stroma) that supports the function of parenchymal (functional) cells within an organ. The stroma is the connective, supportive framework of biological tissues with various functions depending on the specific organ and cell type. Stromal cells, derived from the mesenchymal lineage, play crucial roles in creating, maintaining, and repairing the tissue microenvironment in virtually all mammalian organs, making these cells indispensable to biological function.\nAdditionally, stromal cells secrete growth factors, cytokines, and extracellular matrix (ECM) molecules to constitute an interactive cellular network and ensure an optimal environment for the functional cells. Beyond mere structural support, these cells are instrumental in wound healing, inflammation, and maintaining tissue integrity. They may also influence the behavior of other cell types through direct cell-cell interactions or paracrine signaling.\nClinically and in research, stromal cells often draw attention due to their interaction with tumors in the cancer microenvironment. Over the past years, the role of stromal cells as facilitators of tumor growth and metastasis has been recognized increasingly. They contribute to cancer progression not only by modulating the ECM but also through the secretion of various bioactive molecules and interacting with immune cells, thereby influencing the immunologic responses to tumors.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stromal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stromal cell" @@ -1334,14 +1660,26 @@ "xrefs" : [ { "val" : "FMA:84798" }, { - "val" : "ZFA:0009235" + "val" : "ZFA:0009235", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "A precursor to the smooth muscle cell, the smooth muscle myoblast, is integral to various body systems, including the cardiovascular, gastrointestinal, and respiratory systems. Smooth muscle myoblasts arise from the differentiation of mesenchymal stem cells, a process tightly regulated by specific genetic factors and environmental signals. Their role extends to myogenesis, particularly in the formation of muscular tissue, especially during embryonic development.\nSmooth muscle myoblasts possess distinctive cellular characteristics. In contrast to skeletal muscle myoblasts, they do not fuse to create multinucleated fibers. Instead, they differentiate into individual, uninucleated smooth muscle cells. This differentiation unfolds in two distinct phases: proliferation, marked by rapid division to increase cell numbers, and differentiation, involving structural and functional transformation into mature smooth muscle cells. This intricate process is intricately mediated by various signaling molecules and transcription factors.\nFunctionally, smooth muscle myoblasts and the mature muscle cells they generate play pivotal roles in various physiological processes. Smooth muscle cells orchestrate involuntary muscle responses and are integral to body systems that regulate blood flow, propel food along the digestive tract, and control airflow in the respiratory tract. These diverse functions underscore the significance of smooth muscle myoblasts in the body's growth, maintenance, and overall function.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000514" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000514", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "smooth muscle myoblast on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "smooth muscle myoblast" @@ -1367,7 +1705,13 @@ }, { "val" : "CALOHA:TS-0683" }, { - "val" : "FBbt:00005106" + "val" : "FBbt:00005106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54527" }, { @@ -1375,7 +1719,13 @@ }, { "val" : "WBbt:0003679" }, { - "val" : "ZFA:0009248" + "val" : "ZFA:0009248", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1444,7 +1794,13 @@ "xrefs" : [ { "val" : "FMA:83505" }, { - "val" : "ZFA:0005236" + "val" : "ZFA:0005236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1489,7 +1845,13 @@ "xrefs" : [ { "val" : "FMA:83506" }, { - "val" : "ZFA:0005241" + "val" : "ZFA:0005241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1630,7 +1992,13 @@ "val" : "A megakaryocyte is a large, unique, and complex cell type found primarily in the bone marrow, the spongy, semi-solid tissue located in the medullary cavities of certain bones. The term ‘megakaryocyte’ is derived from the Greek 'mega', meaning great, and 'karyon', referring to the nucleus. Megakaryocytes are characterized by their large size, typically with a diameter of 50-100 µm in humans, and the presence of a multilobulated nucleus; they are the largest hematopoietic cells in the bone marrow but also the rarest cells. \nThe primary function of a megakaryocyte is the production of platelets, also known as thrombocytes. Platelets are small, anucleate cell fragments that play a crucial role in the process of hemostasis, the arrest of blood loss from a damaged blood vessel. The process begins when the megakaryocyte extends long, branching processes called proplatelets, into the sinusoidal blood vessels present in the bone marrow. These proplatelets then fragment into the discoid structures recognized as platelets. Each megakaryocyte can produce thousands of platelets during its lifespan. \nApart from platelet production, megakaryocytes are involved in several other functions. They express immune-sensing receptors such as Fc-γ receptor and Toll-like receptors and produce factors such as platelet factor 4 and platelet-derived growth factor that can stimulate the immune system. Also, in certain pathological conditions, megakaryocytes release TGF-β and PDGF and contribute to bone marrow fibrosis, a condition characterized by excessive accumulation of fibrous tissue in the bone marrow leading to anemia. Recent studies have also highlighted the role of megakaryocytes in regulating hematopoiesis, the process of blood cell production. They can influence the bone marrow microenvironment and control the behavior of hematopoietic stem cells, the progenitors of all types of blood cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1650,7 +2018,13 @@ }, { "val" : "MESH:D012156" }, { - "val" : "ZFA:0009252" + "val" : "ZFA:0009252", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1676,7 +2050,13 @@ "val" : "chondroplast" } ], "xrefs" : [ { - "val" : "ZFA:0009258" + "val" : "ZFA:0009258", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1724,7 +2104,13 @@ "xrefs" : [ { "val" : "BTO:0002315" }, { - "val" : "ZFA:0009387" + "val" : "ZFA:0009387", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1754,7 +2140,13 @@ "xrefs" : [ { "val" : "FMA:84138" }, { - "val" : "ZFA:0005238" + "val" : "ZFA:0005238", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1785,14 +2177,26 @@ }, { "val" : "MESH:D050527" }, { - "val" : "ZFA:0009283" + "val" : "ZFA:0009283", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesangial cells are specialized cells that primarily reside in the middle layer, or mesangium, of the renal glomerulus within the kidney. The primary function of mesangial cells is to maintain the structural stability and function of the glomerular capillary tuft. They achieve this by providing structural support to the capillary loops, controlling the surface area available for filtration in response to physiological alterations in blood pressure, and removing trapped material and proteins from the basement membrane, which otherwise could cause damage. Moreover, mesangial cells regulate the glomerular blood flow by contracting and relaxing, similar to smooth muscle cells. They also synthesize extracellular matrix components, including collagen and fibronectin, that form the structural framework of the glomerulus.\nBeyond their structural and regulatory roles, mesangial cells are involved in several immunologic functions. They express a variety of receptors that can recognize immune complexes and subsequently mediate an inflammatory reaction. Their role in the immune response includes the production of a variety of cytokines and growth factors, which make them a key cellular component in the progression of several renal diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000650" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000650", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesangial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1810,14 +2214,26 @@ "val" : "window cell" } ], "xrefs" : [ { - "val" : "ZFA:0009286" + "val" : "ZFA:0009286", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Fenestrated cells are specialized epithelial cells that are characterized by a distinctive structural feature, fenestrations or tiny pores, which allow an exchange of substances such as fluids, nutrients, and waste between blood vessels and the surrounding tissue environments. These cells are present in various types of epithelial tissues in the human body, including the intestinal tract, endocrine glands, and certain parts of the renal system. \nThere are multiple types of endothelial cell fenestrations. The most common type is found in systemic capillaries of the endocrine tissue (e.g., pancreatic islets), gastrointestinal mucosa, and renal peritubular capillaries. Here, the fenestrated cells have fenestrations in their peripheral cytoplasm with a unique thin and permeable diaphragm that provides a high degree of selectivity, blocking the passage of larger molecules while allowing the free movement of smaller ones. In contrast, other types of fenestrations, such as the discontinuous epithelium of the liver sinusoidal endothelial cells, do not have diaphragms. \nCharacteristically, fenestrated cells play a vital role in the filtering process of body systems. They are a key part of the glomeruli in the kidneys where blood is filtered under high pressure. The fenestrations present in the endothelial cells lining the capillaries of the glomerulus allow the free passage of water and small solute molecules towards the Bowman's capsule, leaving behind larger proteins and cells in the blood, thereby aiding in the filtration and waste removal process. \nIn the endocrine system, fenestrated cells in glandular capillaries allow the prompt release of hormones into the bloodstream. These cells have tightly clustered fenestrations which increase the surface area available for passive diffusion, improving the efficiency of hormone secretion. In villi of the small intestine, these cells increase absorption efficiency, permitting the exchange of water, electrolytes, and nutrients.\nOverall, fenestrated cells contribute immensely to important physiological processes of filtration, absorption, and secretion, primarily connecting our body's circulation system with the surrounding tissues and organs.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000666" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000666", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "fenestrated endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1856,7 +2272,13 @@ }, { "val" : "FMA:63174" }, { - "val" : "ZFA:0009112" + "val" : "ZFA:0009112", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1866,7 +2288,13 @@ "val" : "Pericytes, also known as Rouget cells, are a type of cell embedded in the wall of small blood vessels such as capillaries and venules. Not only do these cells share a basement membrane with endothelial cells, but they also have a direct physical contact with them, forming the blood-brain and blood-retinal barrier. They are an essential component of the neurovascular unit, a structure critical for maintaining brain homeostasis and a consistent neural microenvironment.\nPericytes play a crucial role in the regulation of microvascular blood flow and permeability. They dynamically respond to changes in blood flow and can relax or contract like smooth muscle cells, thereby controlling capillary diameter and blood flow to the tissues. Moreover, pericytes contribute significantly to the regulation of endothelial cell proliferation and migration, implying their vital role in angiogenesis and the stability of blood vessels. Their ability to differentiate into multiple cell types, including fibroblasts, macrophages, and smooth muscle cells, reveals their importance in tissue repair and remodeling.\nFurthermore, pericytes have demonstrated functions in regulating immune and inflammatory responses. Pericytes also collaborate with endothelial cells in preserving the integrity of the blood-brain barrier, thus protecting the central nervous system from potential damage due to harmful substances and pathogens.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000669" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000669", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "pericyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1880,14 +2308,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009291" + "val" : "ZFA:0009291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Muscle precursor cells, commonly referred to as myogenic progenitor cells or myoblasts, play a pivotal role in the intricate processes of muscle regeneration and development. As undifferentiated cells, they harbor the potential to evolve into distinct specialized cells, specifically the muscle cell or myocyte. Their crucial contribution lies in guiding the transformation of the mesodermal layer, one of the three primary germ cell layers in the early embryo, into fully developed skeletal muscle tissues during embryonic development.\nMuscle precursor cells are characterized by their proliferative capacity and rapid differentiation into mature myocytes. They fuse into myotubes, culminating in the formation of muscle fibers. Their responsiveness to signals such as insulin-like growth factors, transforming growth factor-β, and neural inputs enables precise control over their proliferation and differentiation. This regenerative capacity equips them with the ability to repair injured or damaged muscle tissue, a critical function in preserving muscle homeostasis and overall function. These cells also actively contribute to adaptive responses, such as muscle growth and strengthening, in reaction to factors like training or aging.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "muscle precursor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle precursor cell" @@ -1908,14 +2348,26 @@ }, { "val" : "MESH:D053687" }, { - "val" : "ZFA:0009307" + "val" : "ZFA:0009307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Somatic stem cells, also known as adult stem cells, are undifferentiated cells found throughout the body post-embryonic development. They reside in specialized niches within tissues such as the bone marrow, brain, muscles, skin, and liver. Fundamentally, these cells possess the ability to self-renew, maintaining their numbers, and to generate differentiated cells that replace dying cells and repair damaged tissues. \nThe potency of somatic stem cells varies based on their tissue of origin. For instance, hematopoietic stem cells in the bone marrow exhibit multipotency, giving rise to all blood cell types. Conversely, muscle stem cells display unipotency, generating only muscle cells.\nSomatic stem cells respond to environmental signals that regulate their quiescence, activation, and differentiation states. In response to tissue injury, they proliferate and differentiate into specific mature cell types to replace lost or damaged cells. Intricate mechanisms ensure a delicate balance between self-renewal and differentiation, guiding tissue maintenance and repair without risking aberrant cell proliferation leading to tumor formation.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "somatic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somatic stem cell" @@ -1938,7 +2390,13 @@ }, { "val" : "MESH:D022423" }, { - "val" : "ZFA:0009324" + "val" : "ZFA:0009324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1967,7 +2425,13 @@ }, { "val" : "FMA:83516" }, { - "val" : "ZFA:0009325" + "val" : "ZFA:0009325", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2000,7 +2464,13 @@ }, { "val" : "MESH:D004900" }, { - "val" : "ZFA:0005237" + "val" : "ZFA:0005237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2030,7 +2500,13 @@ }, { "val" : "CALOHA:TS-0448" }, { - "val" : "ZFA:0009354" + "val" : "ZFA:0009354", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2062,7 +2538,13 @@ }, { "val" : "FMA:70339" }, { - "val" : "ZFA:0009356" + "val" : "ZFA:0009356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2101,7 +2583,13 @@ }, { "val" : "FMA:83598" }, { - "val" : "ZFA:0005830" + "val" : "ZFA:0005830", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2164,7 +2652,13 @@ "xrefs" : [ { "val" : "FMA:69074" }, { - "val" : "ZFA:0009385" + "val" : "ZFA:0009385", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2194,7 +2688,13 @@ "xrefs" : [ { "val" : "FMA:69076" }, { - "val" : "ZFA:0009388" + "val" : "ZFA:0009388", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2240,7 +2740,13 @@ "val" : "2010-08-24T02:06:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "endothelial cell of vascular tree on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "endothelial cell of vascular tree" @@ -2277,7 +2783,13 @@ "val" : "2010-08-24T10:15:00Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002144" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "capillary endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2409,10 +2921,22 @@ "val" : "An epithelial cell of the proximal tubule, commonly referred to as a proximal tubular epithelial cell, is a specialized brush border cell found lining the proximal tubule within the functional unit of the kidney, the nephron. These cells play a critical role in the resorption process in the kidney and are responsible for maintaining homeostasis, including blood filtration, electrolyte balance, and acid-base balance. Epithelial cells of the proximal tubule have a cuboidal shape and microvilli that increase surface area, facilitating effective reabsorption.\nThe primary function of epithelial cells of the proximal tubule revolves around their ability to reabsorb approximately 60-70% of the glomerular filtrate, retaining essential substances such as sodium, glucose, amino acids, bicarbonate, and certain ions that are filtered out by the glomerulus. Additionally, these cells are also responsible for the secretion of organic acids, bases, and the hydrolysis of small proteins that are reabsorbed after filtration. \nProximal tubule epithelial cells are highly susceptible to apoptosis, and damage to these cells by exposure to toxins, pathogens, or obstructive conditions may result in acute kidney injury.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002306" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002306", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "epithelial cell of proximal tubule on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://xmlns.com/foaf/0.1/depiction", - "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-renal-corpuscle/v1.2/assets/2d-ftu-kidney-renal-corpuscle.png" + "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-renal-corpuscle/v1.2/assets/2d-ftu-kidney-renal-corpuscle.png", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/licence", + "val" : "http://creativecommons.org/licenses/by/4.0/" + } ] + } } ] } }, { @@ -2458,7 +2982,13 @@ }, { "val" : "MESH:D003239" }, { - "val" : "ZFA:0009392" + "val" : "ZFA:0009392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2488,7 +3018,13 @@ }, { "val" : "WBbt:0007028" }, { - "val" : "ZFA:0007089" + "val" : "ZFA:0007089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2501,7 +3037,13 @@ "val" : "2010-09-15T03:39:21Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "embryonic cell (metazoa) on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "embryonic cell (metazoa)" @@ -2555,7 +3097,13 @@ "xrefs" : [ { "val" : "KUPO:0001019" }, { - "val" : "ZFA:0009374" + "val" : "ZFA:0009374", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2625,14 +3173,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0005322" + "val" : "ZFA:0005322", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Renal principal cells are the major cell type in the initial collecting tubule and the cortical and outer medullary collecting ducts, as well as the connecting tubule, in the nephrons of the kidneys.\nA key function of renal principal cells is the regulation of water balance in the body. These cells express aquaporin-2 (AQP2) water channels, which facilitate the reabsorption of water from the fluid within the renal tubule lumen back into the blood. The translocation of AQP2 to the cell membrane is controlled by the hormone vasopressin: In response to high vasopressin levels, AQP2 moves to the cell membrane, allowing water to pass through effectively and be reabsorbed, therefore concentrating the urine. Conversely, in low vasopressin conditions, AQP2 is removed from the membrane, reducing water reabsorption and diluting the urine. \nRenal principal cells are also involved in the regulation of sodium and potassium levels in the body. They have sodium channels (ENaC) in their luminal membranes which permit the reabsorption of sodium ions from the tubule fluid back into the blood, resulting in a net reabsorption of sodium ions into the systemic circulation. This process is controlled, in part, by the hormone aldosterone. Additionally, renal principal cells contain potassium channels that facilitate the secretion of potassium ions into the urine. The activities of these channels, in coordination with other cell types in the nephron, are critical for maintaining electrolyte balance and overall body homeostasis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0005009" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0005009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "renal principal cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2646,7 +3206,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007084" + "val" : "ZFA:0007084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2700,7 +3266,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "FBbt:00005070" + "val" : "FBbt:00005070", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2728,7 +3300,13 @@ "val" : "Mesenchymal cells are a type of undifferentiated cell that possess the ability to develop into a wide variety of other cells. These cells originate from the mesoderm during embryonic development, which gives rise to tissues such as muscles, the skeletal system, and connective and vascular structures. Mesenchymal cells primarily function as progenitor cells with exceptional renewal capabilities and are characterized by their ability to migrate, aiding in tissue repair and regeneration.\nMesenchymal cells play a critical role in the development and maintenance of various biological systems throughout the body due to their versatility and adaptability. They can differentiate into more specialized cells, including osteoblasts, adipocytes, and chondrocytes, which are essential for bone, fat, and cartilage tissues, respectively. Furthermore, they contribute to the vascular and lymphatic systems through the formation of pericytes and lymphatic endothelial cells, securing the integrity of the circulatory system.\nIn the field of regenerative medicine, mesenchymal cells, particularly mesenchymal stem cells (MSCs), are of great interest due to their unique therapeutic potential. MSCs, for instance, have been implicated in wound healing and tissue repair because of their capacity to modulate the immune response. They can secrete a range of proteins and growth factors that aid in angiogenesis, the formation of new blood vessels, and the stimulation of resident progenitor cells to aid in tissue restoration.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesenchymal cell" @@ -2745,7 +3323,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#added_for_HCA", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0005944" + "val" : "ZFA:0005944", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2793,7 +3377,13 @@ "val" : "Neural crest cells are a group of transient and highly migratory cells that originate from the neuroectoderm during the early stages of embryonic development. They are multipotent cells with an exceptional degree of plasticity, capable of differentiating into various somatic cell types and therefore play a fundamental role in the formation of various organs and tissues, making them critical contributors to the developing embryo. \nAfter the initiation of neurulation (the formation of the neural tube) neural crest cells start to undergo epithelial-to-mesenchymal transition and delaminate and migrate from the dorsal neural tube to several regions throughout the embryo. They differentiate into a range of diverse cell types, such as neurons and glial cells of the peripheral nervous system, including sensory and autonomic neurons. They also contribute to the formation of adrenal glands, pigment cells in the skin (melanocytes), cardiac structures, including parts of the heart septum and major arteries, as well as bones and cartilage of the face and skull.\nDisorders or aberrations in the development or migration of the neural crest cells can lead to serious congenital malformations, such as neurocristopathies, including Hirschsprung disease, neuroblastoma, and neurofibromatosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "neural crest cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "neural crest cell" @@ -2915,7 +3505,13 @@ "val" : "Epithelial cells of the nephron form the epithelial lining of the nephron, the functional unit of the kidney that filters the blood to produce urine. Each kidney holds approximately one million nephrons, each of which is composed of several distinct parts, including the renal corpuscle, the proximal tubule, the loop of Henle, and the distal tubule. All sections are lined with highly specialized epithelial cells adapted to perform different functions within the sections of the nephron. \nThe different epithelial cells of the nephron play crucial roles in the process of filtration, reabsorption, secretion, and excretion, essential tasks for the regulation of body fluid composition and volume. During filtration, the blood is forced through the walls of glomerular capillaries into the Bowman's capsule, where waste products, electrolytes, and water are separated from the blood cells and proteins. As the filtrate then passes through the nephron, epithelial cells of the tubular portion reabsorb useful substances such as glucose, amino acids, and electrolytes, along with most of the water back into the bloodstream. Waste products like urea and creatinine, as well as excess ions and water, remain in the tubule for elimination.\nIn addition, epithelial cells of the nephron also play a vital part in maintaining the body's acid-base balance by actively secreting hydrogen ions into the urine while reabsorbing bicarbonate from the urine back into the blood. They are also involved in the regulation of blood pressure through the renin-angiotensin-aldosterone system and contribute to erythrocyte production by releasing the hormone erythropoietin in response to low oxygen levels in the blood. Abnormalities or damage in renal epithelial cells often result in impaired kidney function, leading to various renal diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000449" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "epithelial cell of nephron on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2970,7 +3566,13 @@ "val" : "Kidney collecting duct epithelial cells are a specialized type of cells that form an integral part of the renal system. Located in the collecting duct system of the kidneys, these cells are responsible for one of the final steps in the process of urine formation, and they are instrumental in the fine tuning of the volume and composition of urine by reabsorbing water and certain solutes back into the bloodstream.\nThese cells express specific channels and carriers that actively and passively transport ions and water. They also have channels on their membranes, such as sodium channels and potassium channels, involved in reabsorbing or secreting these electrolytes depending upon the body's needs. The function of renal collecting duct epithelial cells can be regulated by a variety of hormones, including vasopressin (antidiuretic hormone), which can modulate the ion channels and carriers and hence indirectly influence body fluid homeostasis.\nAside from their function in ion and water balance, kidney collecting duct epithelial cells also aid in maintaining the body's acid-base balance. They have specialized functionality to secret hydrogen ions into the tubular lumen, which contributes to acid excretion. Any dysfunction may have serious implications and lead to various renal or systemic diseases, exemplifying the importance of these cells in maintaining overall body homeostasis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000454" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000454", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney collecting duct epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3006,7 +3608,13 @@ "xrefs" : [ { "val" : "KUPO:0001010" }, { - "val" : "ZFA:0009389" + "val" : "ZFA:0009389", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3021,7 +3629,13 @@ "xrefs" : [ { "val" : "KUPO:0001013" }, { - "val" : "ZFA:0009390" + "val" : "ZFA:0009390", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3037,7 +3651,13 @@ "xrefs" : [ { "val" : "KUPO:0001017" }, { - "val" : "ZFA:0009391" + "val" : "ZFA:0009391", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3175,7 +3795,13 @@ "val" : "The kidney interstitial fibroblasts are crucial cells found predominantly in the interstitium of the kidneys. These cells play a significant role in maintaining kidney structure and orchestrating key physiological procedures related to kidney function. The interstitium forms a complex network with other cells, capillaries, and the renal tubules, which are crucial for maintaining kidney functions.\nFunctionally, these cells participate in renal homeostasis by synthesizing and secreting vital extracellular matrix (ECM) components, such as collagen, proteoglycan, and fibronectin, which contribute to the structural integrity of the kidneys. Additionally, these fibroblasts provide supportive tissues to nephrons (structural and functional units of kidneys), help in regulating fluid and electrolyte balance, along with providing an arena for immune response in case of any infection or damage. They are also integral to the regulation of kidney blood flow and maintenance of tubular structures by stabilizing capillaries through synthesis of angiogenic factors.\nUnder pathological conditions, such as renal fibrosis, kidney interstitial fibroblasts can transform into myofibroblasts, which speed up the production and deposition of extracellular matrix proteins. This overproduction can lead to scar formation and affect the kidney's functionality, often leading to a chronic and progressive loss of renal function.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000692" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000692", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney interstitial fibroblast on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3213,10 +3839,22 @@ "val" : "Kidney connecting tubule epithelial cells are found in collecting duct system of the kidney, specifically in at the interconnection segment between the nephron and the collecting ducts. The epithelial cells lining the connecting tubule are crucial for the journey of filtrate before it empties into urine-collecting ducts and therefore play a critical role in maintaining the body’s fluid and electrolyte balance.\nOne of the principal functions of connecting tubule epithelial cells involves the selective reabsorption and secretion of various solutes. This reabsorption process includes critical regulatory electrolytes such as sodium ions (Na+), chloride ions (Cl-), and bicarbonate ions (HCO3-), thus playing a role in the regulation of the acid-base homeostasis. Their function also involves the secretion of potassium ions (K+) into the renal tubular fluid.\nThe connecting tubule epithelial cells are primarily intercalated cells, which can be categorized into two types according to their specific functions: type A intercalated cells, which secrete acid, and the type B intercalated cells, which secrete base (bicarbonate) and reabsorb chloride. By regulating the concentrations of these ions, as well as reabsorption of water, connecting tubule epithelial cells contribute substantively to maintaining the body's electrolyte levels, pH balance, and overall homeostasis.\nIn addition to intercalating cells, the collecting duct system also has principal cells, which are characterized by the expression of the water channel AQP2. AQP2-expressing cells have also been identified in connecting tubules, but there is some controversy whether these represent a unique cell type as there are some morphologic differences compared with principal cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000768" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000768", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney connecting tubule epithelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://xmlns.com/foaf/0.1/depiction", - "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-nephron/v1.2/assets/2d-ftu-kidney-nephron.png" + "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-nephron/v1.2/assets/2d-ftu-kidney-nephron.png", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/licence", + "val" : "http://creativecommons.org/licenses/by/4.0/" + } ] + } } ] } }, { @@ -3240,10 +3878,22 @@ "val" : "Kidney distal convoluted tubule epithelial cells, often referred to simply as distal convoluted tubule (DCT) cells, constitute a significant portion of the nephron -- the functional building unit of the kidney involved in filtration and reabsorption of substances from blood. The DCT epithelial cells form lining of the distal convoluted tubule, a segment of the nephron located after the loop of Henle and before the collecting tubule. These cells are characterized by unique morphological features such as small size, low height and fewer microvilli compared to proximal convoluted tubule epithelial cells. \nThese cells perform a host of vital functions contributing to the regulation of extracellular fluid volume and electrolyte balance, blood pressure and pH. While the DCT is less prominent in water and sodium reabsorption compared to the proximal tubule and the loop of Henle, it plays a crucial role in fine-tuning the process. DCT epithelial cells are responsible for the final adjustments of sodium, potassium and calcium reabsorption, thereby affecting overall fluid and electrolyte balance, blood pressure regulation and bone health. The reabsorption process is regulated by hormones including aldosterone and parathyroid hormone.\nThe distal convoluted tubule (DCT) also plays a significant role in acid-base homeostasis by secreting protons (H+) into the tubular fluid and reabsorbing bicarbonate ions (HCO3-), thus regulating the pH of the blood. The ability of DCT cells to adjust urine concentration plays a part in maintaining the body’s pH balance and preventing conditions like acidosis or alkalosis. In summary, kidney distal convoluted tubule epithelial cells perform functions that are crucial to maintaining body's homeostasis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000849" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000849", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney distal convoluted tubule epithelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://xmlns.com/foaf/0.1/depiction", - "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-nephron/v1.2/assets/2d-ftu-kidney-nephron.png" + "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-nephron/v1.2/assets/2d-ftu-kidney-nephron.png", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/licence", + "val" : "http://creativecommons.org/licenses/by/4.0/" + } ] + } } ] } }, { @@ -3291,7 +3941,13 @@ "val" : "Kidney capillary endothelial cells form the innermost lining of the capillaries and microvessels within kidneys, including those lining the glomerular capillaries and the vasa recta. Each cell exhibits a unique array of adhesion molecules, receptors, and secreted mediators which interact with circulating blood cells and solutes. \nOne of the key functions of kidney capillary endothelial cells is enabling filtration, reabsorption, secretion, and excretion – the crucial steps in the formation of urine. In the glomerulus, these cells form a collaborative relationship with the podocytes to constitute the glomerular filtration barrier; here, the ultra-thin endothelial cells create a wall through which water and small solutes pass while retaining larger proteins and molecules within the bloodstream. This permits the rapid and selective filtration of plasma, a primary aspect of the kidney's role in waste clearance and fluid, electrolyte, and acid-base homeostasis.\nKidney capillary endothelial cells also conduct multiple homeostatic roles, such as vasomotor control, fibrinolysis, platelet adhesion, inflammation, and coagulation. They also play a crucial role in responding to renal injury by participating in fibrogenesis, an initial response following acute kidney injury. The endothelial cells spearhead angiogenesis (new blood vessel formation) and the repair and regeneration of renal tissue, thereby enhancing the survival function of the kidney itself. Furthermore, factors secreted by kidney capillary endothelial cells also help control the growth and differentiation of other types of renal cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000892" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000892", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney capillary endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3354,7 +4010,13 @@ "val" : "The kidney loop of Henle descending limb epithelial cells are highly specialized cells that play a crucial role in maintaining the body's salt and water balance. These cells line the descending limb of the loop of Henle, which is a portion of the renal tubule located in the kidneys, an organ responsible for filtering waste products, ions and extra water from the blood and converting them into urine. However, the descending limb epithelial cells are specifically involved in the countercurrent multiplication system, a mechanism to concentrate urine that involves both active and passive transport processes. \nThese cells are notably permeable to water but relatively impermeable to solutes, a characteristic that dramatically influences the osmotic gradient in the renal medulla. As filtrate initially descends down the loop of Henle, water gets drawn out due to the increasing osmotic gradient, thereby concentrating the filtrate. Additionally, these epithelial cells are exceptionally thin walled, allowing water to freely diffuse across the membrane.\nFurthermore, the kidney loop of Henle descending limb epithelial cells are inextricably linked to the functioning of numerous diuretic drugs, which work by blocking the reabsorption of water and certain electrolytes in the kidneys, leading to increased urine production to rid the body of excess fluids.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1001021" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1001021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney loop of Henle descending limb epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3454,7 +4116,13 @@ }, { "val" : "MetaCyc:PEPTIDYLTRANSFERASE-RXN" }, { - "val" : "Reactome:R-HSA-156912" + "val" : "Reactome:R-HSA-156912", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Peptide transfer from P-site tRNA to the A-site tRNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -3462,6 +4130,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25493" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -3510,7 +4181,13 @@ "val" : "mitosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-69278" + "val" : "Reactome:R-HSA-69278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle, Mitotic" + } ] + } }, { "val" : "Wikipedia:Mitosis" } ], @@ -3700,7 +4377,13 @@ "xrefs" : [ "GOC:dph", "GOC:sdb_2009", "GOC:tb" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9823730" + "val" : "Reactome:R-HSA-9823730", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Formation of definitive endoderm" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3791,41 +4474,6 @@ "val" : "biological_process" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/GO_0001977", - "lbl" : "renal system process involved in regulation of blood volume", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.", - "xrefs" : [ "GOC:dph", "GOC:tb", "ISBN:0721643949" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_obsoletion_candidate" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "renal blood volume control of blood pressure" - }, { - "pred" : "hasRelatedSynonym", - "val" : "renal regulation of blood volume", - "xrefs" : [ "GOC:dph", "GOC:tb" ] - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_2" - }, { - "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_2157" - }, { - "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4896" - }, { - "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4932" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "biological_process" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001990", "lbl" : "regulation of systemic arterial blood pressure by hormone", @@ -4336,7 +4984,13 @@ "val" : "water homeostasis by the renal system" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-432040" + "val" : "Reactome:R-HSA-432040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Vasopressin regulates renal water homeostasis via Aquaporins" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -4449,6 +5103,9 @@ "val" : "molecular function" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is the same as GO molecular function" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -5076,7 +5733,13 @@ "val" : "protein translation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72766" + "val" : "Reactome:R-HSA-72766", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Translation" + } ] + } }, { "val" : "Wikipedia:Translation_(genetics)" } ], @@ -5109,7 +5772,13 @@ "val" : "translation initiation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72613" + "val" : "Reactome:R-HSA-72613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Initiation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5134,7 +5803,13 @@ "val" : "translation elongation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-156842" + "val" : "Reactome:R-HSA-156842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Elongation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5161,7 +5836,13 @@ "val" : "translational complex disassembly" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72764" + "val" : "Reactome:R-HSA-72764", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Termination" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5215,7 +5896,13 @@ "val" : "single-organism transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382551" + "val" : "Reactome:R-HSA-382551", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of small molecules" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -5243,7 +5930,13 @@ "val" : "ion transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-425393" + "val" : "Reactome:R-HSA-425393", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of inorganic cations/anions and amino acids/oligopeptides" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5260,7 +5953,13 @@ "xrefs" : [ "GOC:ai" ] }, "xrefs" : [ { - "val" : "Reactome:R-HSA-445717" + "val" : "Reactome:R-HSA-445717", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Aquaporin-mediated transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5328,7 +6027,13 @@ "val" : "signaling (initiator) caspase activity" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-109581" + "val" : "Reactome:R-HSA-109581", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptosis" + } ] + } }, { "val" : "Wikipedia:Apoptosis" } ], @@ -5378,7 +6083,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-445355" + "val" : "Reactome:R-HSA-445355", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Smooth Muscle Contraction" + } ] + } }, { "val" : "Wikipedia:Muscle_contraction" } ], @@ -5426,7 +6137,13 @@ "val" : "single-organism organelle organization" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1852241" + "val" : "Reactome:R-HSA-1852241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Organelle biogenesis and maintenance" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -5454,7 +6171,13 @@ "val" : "cell-division cycle" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1640170" + "val" : "Reactome:R-HSA-1640170", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle" + } ] + } }, { "val" : "Wikipedia:Cell_cycle" } ], @@ -5528,7 +6251,13 @@ "val" : "signalling pathway" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-212718" + "val" : "Reactome:R-HSA-212718", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "EGFR interacts with phospholipase C-gamma" + } ] + } }, { "val" : "Wikipedia:Signal_transduction" } ], @@ -5578,23 +6307,77 @@ "xrefs" : [ "GOC:dph" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-112316" - }, { - "val" : "Reactome:R-HSA-442720" - }, { - "val" : "Reactome:R-HSA-442729" - }, { - "val" : "Reactome:R-HSA-442742" - }, { - "val" : "Reactome:R-HSA-451307" - }, { - "val" : "Reactome:R-HSA-451308" - }, { - "val" : "Reactome:R-HSA-9619229" - }, { - "val" : "Reactome:R-HSA-9619483" - }, { - "val" : "Reactome:R-HSA-9620244" + "val" : "Reactome:R-HSA-112316", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Neuronal System" + } ] + } + }, { + "val" : "Reactome:R-HSA-442720", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through the activation of Adenylate Cyclase" + } ] + } + }, { + "val" : "Reactome:R-HSA-442729", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde" + } ] + } + }, { + "val" : "Reactome:R-HSA-442742", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" + } ] + } + }, { + "val" : "Reactome:R-HSA-451307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of Na-permeable kainate receptors" + } ] + } + }, { + "val" : "Reactome:R-HSA-451308", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of Ca-permeable Kainate Receptor" + } ] + } + }, { + "val" : "Reactome:R-HSA-9619229", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of RAC1 downstream of NMDARs" + } ] + } + }, { + "val" : "Reactome:R-HSA-9619483", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of AMPK downstream of NMDARs" + } ] + } + }, { + "val" : "Reactome:R-HSA-9620244", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Long-term potentiation" + } ] + } }, { "val" : "Wikipedia:Neurotransmission" } ], @@ -5672,7 +6455,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9758941" + "val" : "Reactome:R-HSA-9758941", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Gastrulation" + } ] + } }, { "val" : "Wikipedia:Gastrulation" } ], @@ -5710,7 +6499,13 @@ "val" : "pan-neural process" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9675108" + "val" : "Reactome:R-HSA-9675108", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Nervous system development" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5774,7 +6569,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8935690" + "val" : "Reactome:R-HSA-8935690", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Digestion" + } ] + } }, { "val" : "Wikipedia:Digestion" } ], @@ -5902,7 +6703,13 @@ "val" : "establishment and maintenance of protein localization" } ], "xrefs" : [ { - 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"val" : "Reactome:R-HSA-5357801" + "val" : "Reactome:R-HSA-5357801", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Programmed Cell Death" + } ] + } }, { "val" : "Wikipedia:Programmed_cell_death" } ], @@ -6666,7 +7491,13 @@ "xrefs" : [ "GOC:ai" ] }, "xrefs" : [ { - "val" : "Reactome:R-HSA-8981607" + "val" : "Reactome:R-HSA-8981607", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Intracellular oxygen transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -6794,7 +7625,13 @@ "val" : "RNA metabolism" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953854" + "val" : "Reactome:R-HSA-8953854", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of RNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -6851,17 +7688,42 @@ "xrefs" : [ { "val" : "EC:2.-.-.-" }, { - 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"val" : "Reactome:R-HSA-392499" + "val" : "Reactome:R-HSA-392499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of proteins" + } ] + } }, { "val" : "Wikipedia:Protein_metabolism" } ], @@ -7284,7 +8182,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -7298,6 +8196,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/26279" }, { @@ -7314,6 +8215,7 @@ "val" : "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:18391171" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "formation of a cell surface projection" @@ -7323,6 +8225,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -7872,6 +8777,9 @@ "val" : "protein-protein complex" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is not covalently bonded, which conflicts with changes to the parent definition." + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -7956,7 +8864,13 @@ "val" : "ATP hydrolysis coupled ion transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-983712" + "val" : "Reactome:R-HSA-983712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ion channel transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -8153,8 +9067,8 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "Any biological process involved in the maintenance of an internal steady state.", - "xrefs" : [ "GOC:jl", "ISBN:0395825172" ] + "val" : "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions.", + "xrefs" : [ "PMID:26265027" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_mouse" ], "synonyms" : [ { @@ -8177,6 +9091,9 @@ "val" : "regulation of homeostatic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/31175" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8300,7 +9217,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -8312,6 +9229,9 @@ "val" : "cellular projection" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" }, { @@ -9058,7 +9978,13 @@ "val" : "reproductive process in a multicellular organism" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1474165" + "val" : "Reactome:R-HSA-1474165", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Reproduction" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -9650,7 +10576,13 @@ "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953897" + "val" : "Reactome:R-HSA-8953897", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cellular responses to stimuli" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -9676,11 +10608,29 @@ "val" : "ATP hydrolysis coupled transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382556" + "val" : "Reactome:R-HSA-382556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ABC-family proteins mediated transport" + } ] + } }, { - "val" : "Reactome:R-HSA-425407" + "val" : "Reactome:R-HSA-425407", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "SLC-mediated transmembrane transport" + } ] + } }, { - "val" : "Reactome:R-HSA-5223345" + "val" : "Reactome:R-HSA-5223345", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Miscellaneous transport and binding events" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", @@ -10061,24 +11011,6 @@ "val" : "biological_process" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/GO_0071705", - "lbl" : "nitrogen compound transport", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.", - "xrefs" : [ "GOC:mah" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_obsoletion_candidate" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2010-03-08T03:56:28Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "biological_process" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/GO_0071826", "lbl" : "protein-RNA complex organization", @@ -10259,11 +11191,29 @@ "val" : "induction of apoptosis by extracellular signals" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-193681" + "val" : "Reactome:R-HSA-193681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ceramide signalling" + } ] + } }, { - "val" : "Reactome:R-HSA-204998" + "val" : "Reactome:R-HSA-204998", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell death signalling via NRAGE, NRIF and NADE" + } ] + } }, { - "val" : "Reactome:R-HSA-75157" + "val" : "Reactome:R-HSA-75157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "FasL/ CD95L signaling" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -10293,7 +11243,13 @@ "val" : "apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-75153" + "val" : "Reactome:R-HSA-75153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptotic execution phase" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -10442,7 +11398,7 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098643", - "lbl" : "fibrillar collagen", + "lbl" : "fibrillar collagen complex", "type" : "CLASS", "meta" : { "definition" : { @@ -10452,6 +11408,9 @@ "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "banded collagen fibril" + }, { + "pred" : "hasExactSynonym", + "val" : "fibrillar collagen" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -10495,14 +11454,21 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098645", - "lbl" : "collagen network", + "lbl" : "complex of network-forming collagens", "type" : "CLASS", "meta" : { "definition" : { "val" : "A supramolecular complex that consists of collagen triple helices associated to form a network.", "xrefs" : [ "GOC:dos", "PMID:21421911" ] }, + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "collagen network" + } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30938" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -10650,8 +11616,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.", - "xrefs" : [ "GOC:kmv" ] + "val" : "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { @@ -10659,6 +11624,12 @@ "val" : "cellular anatomical entity" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Overlaps with some cellular components from GO" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" }, { @@ -11552,6 +12523,46 @@ "val" : "Eukaryota" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "lbl" : "Choanoflagellata", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "choanoflagellates" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellatea" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellida" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanomonada" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanozoa" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "choanoflagellates" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + }, { + "val" : "PMID:27765632" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "lbl" : "Euarchontoglires", @@ -12589,6 +13600,21 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0001591", + "lbl" : "curvature", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.", + "xrefs" : [ "WordNet:WordNet" ] + }, + "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0001690", "lbl" : "contractile", @@ -12945,6 +13971,32 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0002254", + "lbl" : "flattened", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane.", + "xrefs" : [ "PATOC:CVS" ] + }, + "comments" : [ "Becoming flat but not necessarily completely flat." ], + "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], + "synonyms" : [ { + "pred" : "hasRelatedSynonym", + "val" : "compressed" + } ], + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0002-2061-091X" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2010-08-16T03:59:34Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002266", "lbl" : "3-D shape", @@ -14383,11 +15435,23 @@ }, { "val" : "EHDAA2:0003193" }, { - "val" : "EMAPA:37283" + "val" : "EMAPA:37283", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100155" }, { - "val" : "FBbt:00007000" + "val" : "FBbt:00007000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000144" }, { @@ -14399,7 +15463,13 @@ }, { "val" : "NCIT:C61460" }, { - "val" : "UMLS:C0598782" + "val" : "UMLS:C0598782", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Appendage" + } ] + } }, { "val" : "VSAO:0000075" }, { @@ -14449,7 +15519,13 @@ }, { "val" : "TAO:0005425" }, { - "val" : "UMLS:C0036760" + "val" : "UMLS:C0036760", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Serosa" + } ] + } }, { "val" : "Wikipedia:Serous_membrane" }, { @@ -14535,7 +15611,13 @@ }, { "val" : "SCTID:302511008" }, { - "val" : "UMLS:C0041951" + "val" : "UMLS:C0041951", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ureter" + } ] + } }, { "val" : "VHOG:0000605" }, { @@ -14590,7 +15672,13 @@ }, { "val" : "SCTID:302513006" }, { - "val" : "UMLS:C0041967" + "val" : "UMLS:C0041967", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Urethra" + } ] + } }, { "val" : "VHOG:0001264" }, { @@ -14633,7 +15721,13 @@ "xrefs" : [ { "val" : "AAO:0011123" }, { - "val" : "FBbt:00100314" + "val" : "FBbt:00100314", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:30320" }, { @@ -14643,7 +15737,13 @@ }, { "val" : "TAO:0005171" }, { - "val" : "UMLS:C0687028" + "val" : "UMLS:C0687028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Duct" + } ] + } }, { "val" : "Wikipedia:Duct_(anatomy)" }, { @@ -14723,7 +15823,13 @@ }, { "val" : "FAO:0000001" }, { - "val" : "FBbt:00007001" + "val" : "FBbt:00007001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:305751" }, { @@ -14808,7 +15914,13 @@ }, { "val" : "SCTID:272625005" }, { - "val" : "UMLS:C0178784" + "val" : "UMLS:C0178784", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ" + } ] + } }, { "val" : "WBbt:0003760" }, { @@ -14816,7 +15928,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33090" @@ -14936,47 +16054,161 @@ }, { "val" : "BilaDO:0000004" }, { - "val" : "BtauDv:0000078" - }, { - "val" : "CfamDv:0000007" - }, { - "val" : "ChirDv:0000014" - }, { - "val" : "DpseDv:0000005" - }, { - "val" : "DsimDv:0000005" + "val" : "BtauDv:0000078", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001272" }, { - "val" : "EcabDv:0000007" + "val" : "EcabDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005369" }, { - "val" : "FcatDv:0000007" - }, { - "val" : "GgalDv:0000076" - }, { - "val" : "GgorDv:0000032" - }, { - "val" : "HsapDv:0010000" - }, { - "val" : "MmulDv:0000052" - }, { - "val" : "MmusDv:0000092" - }, { - "val" : "OanaDv:0000007" - }, { - "val" : "OariDv:0000024" - }, { - "val" : "PpanDv:0000041" - }, { - "val" : "PtroDv:0000052" - }, { - "val" : "RnorDv:0000061" - }, { - "val" : "SsalDv:0000040" - }, { - "val" : "SscrDv:0000084" + "val" : "FcatDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000076", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000032", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0010000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000041", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000061", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000041" }, { @@ -15007,65 +16239,203 @@ "val" : "embryogenesis" } ], "xrefs" : [ { - 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"val" : "EcabDv:0000002" + "val" : "EcabDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005289" }, { "val" : "FMA:72652" }, { - "val" : "FcatDv:0000002" - }, { - "val" : "GgalDv:0000002" - }, { - "val" : "GgorDv:0000002" - }, { - "val" : "HsapDv:0000045" - }, { - "val" : "MdomDv:0000002" - }, { - "val" : "MmulDv:0000002" - }, { - "val" : "MmusDv:0000042" + "val" : "FcatDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000045", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000042", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000000" }, { "val" : "OGES:000022" }, { - 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"val" : "SsalDv:0000002" - }, { - "val" : "SscrDv:0000002" + "val" : "SsalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000003" }, { @@ -15184,7 +16554,13 @@ }, { "val" : "TAO:0001288" }, { - "val" : "UMLS:C0022663" + "val" : "UMLS:C0022663", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Glomerulus" + } ] + } }, { "val" : "Wikipedia:Glomerulus" }, { @@ -15232,7 +16608,13 @@ }, { "val" : "SCTID:118966000" }, { - "val" : "UMLS:C1519343" + "val" : "UMLS:C1519343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System_Part" + } ] + } }, { "val" : "galen:ComplexSkeletalStructure" } ], @@ -15317,7 +16699,13 @@ }, { "val" : "TAO:0000529" }, { - "val" : "UMLS:C0025492" + "val" : "UMLS:C0025492", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesonephros" + } ] + } }, { "val" : "VHOG:0000038" }, { @@ -15382,7 +16770,13 @@ }, { "val" : "SCTID:308797000" }, { - "val" : "UMLS:C0231049" + "val" : "UMLS:C0231049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Metanephros" + } ] + } }, { "val" : "VHOG:0000039" }, { @@ -15486,7 +16880,13 @@ }, { "val" : "SCTID:361528000" }, { - "val" : "UMLS:C1284058" + "val" : "UMLS:C1284058", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Metanephric_Diverticulum" + } ] + } }, { "val" : "VHOG:0000541" }, { @@ -15521,7 +16921,13 @@ }, { "val" : "OGES:000024" }, { - "val" : "SsalDv:0000038" + "val" : "SsalDv:0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000022" }, { @@ -15591,55 +16997,193 @@ "val" : "lifespan" } ], "xrefs" : [ { - 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"val" : "FcatDv:0000001" - }, { - "val" : "GgalDv:0000001" - }, { - "val" : "GgorDv:0000001" - }, { - "val" : "HsapDv:0000001" - }, { - "val" : "MdomDv:0000001" - }, { - "val" : "MmulDv:0000001" - }, { - "val" : "MmusDv:0000001" + "val" : "FcatDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000011" }, { - "val" : "OanaDv:0000001" - }, { - "val" : "OariDv:0000001" - }, { - "val" : "OcunDv:0000001" - }, { - "val" : "PpanDv:0000001" - }, { - "val" : "PtroDv:0000001" - }, { - "val" : "RnorDv:0000001" - }, { - "val" : "SsalDv:0000001" - }, { - "val" : "SscrDv:0000001" + "val" : "OanaDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "ncithesaurus:Life" } ], @@ -15678,63 +17222,201 @@ "val" : "stage" } ], "xrefs" : [ { - "val" : "AcarDv:0000000" + "val" : "AcarDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BILS:0000105" }, { - "val" : "BtauDv:0000000" - }, { - "val" : "CfamDv:0000000" - }, { - "val" : "ChirDv:0000000" - }, { - "val" : "CporDv:0000000" - }, { - "val" : "DpseDv:0000000" - }, { - "val" : "DsimDv:0000000" + "val" : "BtauDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0000399" }, { - "val" : "EcabDv:0000000" + "val" : "EcabDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00007012" }, { "val" : "FMA:24120" }, { - "val" : "FcatDv:0000000" - }, { - "val" : "GgalDv:0000000" - }, { - "val" : "GgorDv:0000000" - }, { - "val" : "HsapDv:0000000" + "val" : "FcatDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D008018" }, { - "val" : "MdomDv:0000000" - }, { - "val" : "MmulDv:0000000" - }, { - "val" : "MmusDv:0000000" - }, { - "val" : "OanaDv:0000000" - }, { - "val" : "OariDv:0000000" - }, { - "val" : "OcunDv:0000000" + "val" : "MdomDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000090" }, { - "val" : "PpanDv:0000000" - }, { - "val" : "PtroDv:0000000" - }, { - "val" : "RnorDv:0000000" - }, { - "val" : "SsalDv:0000000" - }, { - "val" : "SscrDv:0000000" + "val" : "PpanDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000002" }, { @@ -15805,7 +17487,13 @@ }, { "val" : "BilaDO:0000005" }, { - "val" : "ChirDv:0000003" + "val" : "ChirDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001322" }, { @@ -15813,21 +17501,57 @@ }, { "val" : "FBdv:00005288" }, { - "val" : "HsapDv:0000003" - }, { - "val" : "MmusDv:0000003" + "val" : "HsapDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "NCIT:C12601" }, { - "val" : "OariDv:0000009" + "val" : "OariDv:0000009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000100" }, { - "val" : "RnorDv:0000048" - }, { - "val" : "SsalDv:0000003" - }, { - "val" : "SscrDv:0000087" + "val" : "RnorDv:0000048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "VHOG:0000745" }, { @@ -15860,33 +17584,81 @@ }, { "val" : "BilaDO:0000006" }, { - "val" : "ChirDv:0000004" + "val" : "ChirDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001290" }, { "val" : "FBdv:00000054" }, { - "val" : "GgalDv:0000064" - }, { - "val" : "HsapDv:0000005" + "val" : "GgalDv:0000064", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D002970" }, { - "val" : "MmusDv:0000004" + "val" : "MmusDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000015" }, { "val" : "OGES:000020" }, { - "val" : "OariDv:0000010" + "val" : "OariDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000200" }, { - "val" : "RnorDv:0000049" - }, { - "val" : "SsalDv:0000004" - }, { - "val" : "SscrDv:0000088" + "val" : "RnorDv:0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000088", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Cleavage_(embryo)" }, { @@ -15914,15 +17686,39 @@ }, { "val" : "BilaDO:0000007" }, { - "val" : "ChirDv:0000010" + "val" : "ChirDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001282" }, { - "val" : "GgalDv:0000091" - }, { - "val" : "HsapDv:0000006" - }, { - "val" : "MmusDv:0000007" + "val" : "GgalDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000003" }, { @@ -15930,13 +17726,37 @@ }, { "val" : "OGES:000021" }, { - "val" : "OariDv:0000025" - }, { - "val" : "RnorDv:0000054" - }, { - "val" : "SsalDv:0000012" - }, { - "val" : "SscrDv:0000089" + "val" : "OariDv:0000025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000005" }, { @@ -15997,29 +17817,77 @@ }, { "val" : "BilaDO:0000008" }, { - "val" : "ChirDv:0000011" + "val" : "ChirDv:0000011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001296" }, { "val" : "FBdv:00005317" }, { - "val" : "GgalDv:0000092" - }, { - "val" : "HsapDv:0000010" - }, { - "val" : "MmusDv:0000013" + "val" : "GgalDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000004" }, { "val" : "OGES:000019" }, { - "val" : "OariDv:0000026" - }, { - "val" : "RnorDv:0000005" - }, { - "val" : "SsalDv:0000016" - }, { - "val" : "SscrDv:0000090" + "val" : "OariDv:0000026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000010" }, { @@ -16046,19 +17914,61 @@ }, { "val" : "BilaDO:0000009" }, { - "val" : "ChirDv:0000012" - }, { - "val" : "GgalDv:0000093" - }, { - "val" : "HsapDv:0000012" - }, { - "val" : "MmusDv:0000017" - }, { - "val" : "OariDv:0000027" - }, { - "val" : "RnorDv:0000007" - }, { - "val" : "SscrDv:0000091" + "val" : "ChirDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "XAO:1000006" } ], @@ -16091,25 +18001,73 @@ }, { "val" : "BilaDO:0000010" }, { - "val" : "ChirDv:0000013" - }, { - "val" : "GgalDv:0000094" - }, { - "val" : "HsapDv:0000015" - }, { - "val" : "MmusDv:0000018" + "val" : "ChirDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000018", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000005" }, { "val" : "OGES:000032" }, { - "val" : "OariDv:0000028" - }, { - "val" : "RnorDv:0000055" - }, { - "val" : "SsalDv:0000022" - }, { - "val" : "SscrDv:0000086" + "val" : "OariDv:0000028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Organogenesis" } ], @@ -16261,7 +18219,13 @@ }, { "val" : "SCTID:370631000" }, { - "val" : "UMLS:C0008987" + "val" : "UMLS:C0008987", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cloaca" + } ] + } }, { "val" : "VHOG:0001186" }, { @@ -16348,7 +18312,13 @@ }, { "val" : "SCTID:50961009" }, { - "val" : "UMLS:C0231057" + "val" : "UMLS:C0231057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Urogenital_Sinus" + } ] + } }, { "val" : "VHOG:0000414" }, { @@ -16443,7 +18413,13 @@ }, { "val" : "EMAPA:16262" }, { - "val" : "FBbt:00003126" + "val" : "FBbt:00003126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:49184" }, { @@ -16602,7 +18578,13 @@ }, { "val" : "TAO:0000007" }, { - "val" : "UMLS:C0005767" + "val" : "UMLS:C0005767", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood" + } ] + } }, { "val" : "VHOG:0000224" }, { @@ -16739,7 +18721,13 @@ }, { "val" : "NCIT:C74601" }, { - "val" : "UMLS:C0933845" + "val" : "UMLS:C0933845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Parenchyma" + } ] + } }, { "val" : "Wikipedia:Parenchyma" } ], @@ -16824,7 +18812,13 @@ }, { "val" : "SCTID:30737000" }, { - "val" : "UMLS:C0022664" + "val" : "UMLS:C0022664", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Medulla" + } ] + } }, { "val" : "Wikipedia:Renal_medulla" }, { @@ -16941,7 +18935,13 @@ "xrefs" : [ { "val" : "BTO:0001837" }, { - "val" : "EMAPA:37950" + "val" : "EMAPA:37950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:62889" }, { @@ -17010,7 +19010,13 @@ }, { "val" : "NCIT:C34062" }, { - "val" : "UMLS:C1516992" + "val" : "UMLS:C1516992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland_Fluid_or_Secretion" + } ] + } }, { "val" : "galen:Secretion" } ], @@ -17065,7 +19071,13 @@ }, { "val" : "EMAPA:35178" }, { - "val" : "FBbt:00007019" + "val" : "FBbt:00007019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9669" }, { @@ -17139,7 +19151,13 @@ }, { "val" : "EHDAA2:0003005" }, { - "val" : "FBbt:00007017" + "val" : "FBbt:00007017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:5897" }, { @@ -17151,7 +19169,13 @@ }, { "val" : "TGMA:0001825" }, { - "val" : "UMLS:C0524461" + "val" : "UMLS:C0524461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lumen_Space" + } ] + } }, { "val" : "VHOG:0001728" }, { @@ -17194,7 +19218,13 @@ }, { "val" : "EHDAA2:0003006" }, { - "val" : "FBbt:00007016" + "val" : "FBbt:00007016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67165" }, { @@ -17246,7 +19276,13 @@ }, { "val" : "EHDAA2:0003007" }, { - "val" : "FBbt:00007015" + "val" : "FBbt:00007015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67112" }, { @@ -17326,7 +19362,13 @@ }, { "val" : "EV:0100000" }, { - "val" : "FBbt:00004856" + "val" : "FBbt:00004856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7149" }, { @@ -17342,7 +19384,13 @@ }, { "val" : "TGMA:0001831" }, { - "val" : "UMLS:C0460002" + "val" : "UMLS:C0460002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_System" + } ] + } }, { "val" : "VHOG:0001725" }, { @@ -17440,7 +19488,13 @@ }, { "val" : "EV:0100016" }, { - "val" : "FBbt:00000001" + "val" : "FBbt:00000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:256135" }, { @@ -17574,7 +19628,13 @@ }, { "val" : "EMAPA:36031" }, { - "val" : "FBbt:00007009" + "val" : "FBbt:00007009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7153" }, { @@ -17594,7 +19654,13 @@ }, { "val" : "TGMA:0001840" }, { - "val" : "UMLS:C0229962" + "val" : "UMLS:C0229962", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Body_Part" + } ] + } }, { "val" : "VHOG:0001758" }, { @@ -17650,7 +19716,13 @@ }, { "val" : "EHDAA2:0003040" }, { - "val" : "FBbt:00007013" + "val" : "FBbt:00007013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:63863" }, { @@ -17689,7 +19761,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007277" + "val" : "FBbt:00007277", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "VHOG:0001737" } ], @@ -17748,7 +19826,13 @@ }, { "val" : "EMAPA:35868" }, { - "val" : "FBbt:00007003" + "val" : "FBbt:00007003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9637" }, { @@ -17764,7 +19848,13 @@ }, { "val" : "TGMA:0001844" }, { - "val" : "UMLS:C0040300" + "val" : "UMLS:C0040300", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Tissue" + } ] + } }, { "val" : "VHOG:0001757" }, { @@ -17820,7 +19910,13 @@ }, { "val" : "EHDAA2:0003055" }, { - "val" : "FBbt:00007010" + "val" : "FBbt:00007010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000055" }, { @@ -17886,7 +19982,13 @@ }, { "val" : "EMAPA:32738" }, { - "val" : "FBbt:00007005" + "val" : "FBbt:00007005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9639" }, { @@ -17904,7 +20006,13 @@ }, { "val" : "TAO:0001486" }, { - "val" : "UMLS:C0014609" + "val" : "UMLS:C0014609", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Epithelium" + } ] + } }, { "val" : "VHOG:0000387" }, { @@ -17963,7 +20071,13 @@ }, { "val" : "EHDAA2_RETIRED:0003068" }, { - "val" : "FBbt:00007027" + "val" : "FBbt:00007027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45567" }, { @@ -17975,7 +20089,13 @@ }, { "val" : "TAO:0001496" }, { - "val" : "UMLS:C0836135" + "val" : "UMLS:C0836135", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Columnar_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_columnar_epithelium" }, { @@ -18032,7 +20152,13 @@ }, { "val" : "TAO:0001494" }, { - "val" : "UMLS:C0682575" + "val" : "UMLS:C0682575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stratified_Epithelium" + } ] + } }, { "val" : "Wikipedia:Stratified_epithelium" }, { @@ -18085,7 +20211,13 @@ }, { "val" : "TAO:0001498" }, { - "val" : "UMLS:C0836133" + "val" : "UMLS:C0836133", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_squamous_epithelium" }, { @@ -18194,7 +20326,13 @@ }, { "val" : "TAO:0001495" }, { - "val" : "UMLS:C0682574" + "val" : "UMLS:C0682574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Epithelium" + } ] + } }, { "val" : "XAO:0004007" }, { @@ -18359,7 +20497,13 @@ }, { "val" : "EMAPA:16039" }, { - "val" : "FBbt:00000052" + "val" : "FBbt:00000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69068" }, { @@ -18377,7 +20521,13 @@ }, { "val" : "SCTID:57991002" }, { - "val" : "UMLS:C0013935" + "val" : "UMLS:C0013935", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryo" + } ] + } }, { "val" : "VHOG:0001766" }, { @@ -18439,7 +20589,13 @@ }, { "val" : "EMAPA:36033" }, { - "val" : "FBbt:00000110" + "val" : "FBbt:00000110", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69069" }, { @@ -18453,9 +20609,21 @@ }, { "val" : "TAO:0001122" }, { - "val" : "UMLS:C0920502" - }, { - "val" : "UMLS:C1708239" + "val" : "UMLS:C0920502", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Tissue" + } ] + } + }, { + "val" : "UMLS:C1708239", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Germinal_Layer" + } ] + } }, { "val" : "VHOG:0001223" }, { @@ -18502,7 +20670,13 @@ }, { "val" : "EV:0100003" }, { - "val" : "FBbt:00000111" + "val" : "FBbt:00000111", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69070" }, { @@ -18522,7 +20696,13 @@ }, { "val" : "TAO:0000016" }, { - "val" : "UMLS:C0013574" + "val" : "UMLS:C0013574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ectoderm" + } ] + } }, { "val" : "VHOG:0000153" }, { @@ -18573,7 +20753,13 @@ }, { "val" : "EV:0100005" }, { - "val" : "FBbt:00000125" + "val" : "FBbt:00000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69071" }, { @@ -18591,7 +20777,13 @@ }, { "val" : "TAO:0000017" }, { - "val" : "UMLS:C0014144" + "val" : "UMLS:C0014144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endoderm" + } ] + } }, { "val" : "VHOG:0000154" }, { @@ -18657,7 +20849,13 @@ }, { "val" : "EV:0100006" }, { - "val" : "FBbt:00000126" + "val" : "FBbt:00000126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69072" }, { @@ -18675,7 +20873,13 @@ }, { "val" : "TAO:0000041" }, { - "val" : "UMLS:C0025485" + "val" : "UMLS:C0025485", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesoderm" + } ] + } }, { "val" : "VHOG:0000152" }, { @@ -18745,7 +20949,13 @@ }, { "val" : "EMAPA:16263" }, { - "val" : "FBbt:00000439" + "val" : "FBbt:00000439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:295846" }, { @@ -18755,7 +20965,13 @@ }, { "val" : "TGMA:0000135" }, { - "val" : "UMLS:C1514977" + "val" : "UMLS:C1514977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stomodeum" + } ] + } }, { "val" : "Wikipedia:Stomodeum" }, { @@ -18810,13 +21026,25 @@ }, { "val" : "EMAPA:25038" }, { - "val" : "FBbt:00000123" + "val" : "FBbt:00000123", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "NCIT:C34278" }, { "val" : "TAO:0000066" }, { - "val" : "UMLS:C0231054" + "val" : "UMLS:C0231054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Proctodeum" + } ] + } }, { "val" : "VHOG:0000139" }, { @@ -18913,7 +21141,13 @@ }, { "val" : "TAO:0000114" }, { - "val" : "UMLS:C0018787" + "val" : "UMLS:C0018787", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Heart" + } ] + } }, { "val" : "VHOG:0000276" }, { @@ -19053,7 +21287,13 @@ }, { "val" : "TAO:0000367" }, { - "val" : "UMLS:C0022417" + "val" : "UMLS:C0022417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint" + } ] + } }, { "val" : "VHOG:0001276" }, { @@ -19136,7 +21376,13 @@ }, { "val" : "EV:0100100" }, { - "val" : "FBbt:00004857" + "val" : "FBbt:00004857", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7160" }, { @@ -19148,7 +21394,13 @@ }, { "val" : "MA:0000326" }, { - "val" : "MESH:D005835" + "val" : "MESH:D005835", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000305" }, { @@ -19158,7 +21410,13 @@ }, { "val" : "TAO:0000632" }, { - "val" : "UMLS:C1261210" + "val" : "UMLS:C1261210", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Reproductive_System" + } ] + } }, { "val" : "VHOG:0000182" }, { @@ -19233,7 +21491,13 @@ }, { "val" : "TAO:0000413" }, { - "val" : "UMLS:C0018067" + "val" : "UMLS:C0018067", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gonad" + } ] + } }, { "val" : "VHOG:0000397" }, { @@ -19284,7 +21548,13 @@ }, { "val" : "EFO:0000793" }, { - "val" : "FBbt:00005055" + "val" : "FBbt:00005055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7152" }, { @@ -19381,7 +21651,13 @@ }, { "val" : "EV:0100095" }, { - "val" : "FBbt:00005056" + "val" : "FBbt:00005056", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7159" }, { @@ -19403,7 +21679,13 @@ }, { "val" : "TAO:0000163" }, { - "val" : "UMLS:C1508753" + "val" : "UMLS:C1508753", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Urinary_System" + } ] + } }, { "val" : "VHOG:0000723" }, { @@ -19419,10 +21701,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -19452,7 +21746,13 @@ }, { "val" : "CALOHA:TS-2103" }, { - "val" : "MESH:D002319" + "val" : "MESH:D002319", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "VHOG:0001248" }, { @@ -19460,7 +21760,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6073" @@ -19532,7 +21838,13 @@ }, { "val" : "TAO:0000548" }, { - "val" : "UMLS:C0026845" + "val" : "UMLS:C0026845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle" + } ] + } }, { "val" : "VSAO:0005038" }, { @@ -19595,7 +21907,13 @@ }, { "val" : "EV:0100162" }, { - "val" : "FBbt:00005093" + "val" : "FBbt:00005093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7157" }, { @@ -19615,7 +21933,13 @@ }, { "val" : "TAO:0000396" }, { - "val" : "UMLS:C0027763" + "val" : "UMLS:C0027763", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System" + } ] + } }, { "val" : "VHOG:0000402" }, { @@ -19699,7 +22023,13 @@ }, { "val" : "EV:0100163" }, { - "val" : "FBbt:00005094" + "val" : "FBbt:00005094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:55675" }, { @@ -19717,7 +22047,16 @@ }, { "val" : "TAO:0000012" }, { - "val" : "UMLS:C0927232" + "val" : "UMLS:C0927232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1099" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Central_Nervous_System" + } ] + } }, { "val" : "VHOG:0000293" }, { @@ -19731,7 +22070,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -19774,7 +22119,13 @@ }, { "val" : "EMAPA:16548" }, { - "val" : "FBbt:00005379" + "val" : "FBbt:00005379", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45616" }, { @@ -19786,7 +22137,13 @@ }, { "val" : "TGMA:0001014" }, { - "val" : "UMLS:C0231051" + "val" : "UMLS:C0231051", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Foregut" + } ] + } }, { "val" : "VHOG:0000285" }, { @@ -19834,7 +22191,13 @@ }, { "val" : "EMAPA:16255" }, { - "val" : "FBbt:00005383" + "val" : "FBbt:00005383", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45617" }, { @@ -19846,7 +22209,13 @@ }, { "val" : "TGMA:0001036" }, { - "val" : "UMLS:C0231052" + "val" : "UMLS:C0231052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Midgut" + } ] + } }, { "val" : "VHOG:0000290" }, { @@ -19894,7 +22263,13 @@ }, { "val" : "EMAPA:16715" }, { - "val" : "FBbt:00005384" + "val" : "FBbt:00005384", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45618" }, { @@ -19906,7 +22281,13 @@ }, { "val" : "TGMA:0001020" }, { - "val" : "UMLS:C0231053" + "val" : "UMLS:C0231053", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hindgut" + } ] + } }, { "val" : "VHOG:0000459" }, { @@ -19963,7 +22344,13 @@ }, { "val" : "EHDAA2:0003171" }, { - "val" : "FBbt:00005495" + "val" : "FBbt:00005495", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86589" }, { @@ -19971,7 +22358,13 @@ }, { "val" : "NCIT:C34275" }, { - "val" : "UMLS:C0678727" + "val" : "UMLS:C0678727", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium" + } ] + } }, { "val" : "Wikipedia:Primordium" }, { @@ -20035,7 +22428,13 @@ }, { "val" : "TAO:0001135" }, { - "val" : "UMLS:C0231024" + "val" : "UMLS:C0231024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Tube" + } ] + } }, { "val" : "VHOG:0000307" }, { @@ -20080,7 +22479,13 @@ }, { "val" : "EHDAA2:0002229" }, { - "val" : "FBbt:10000000" + "val" : "FBbt:10000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:62955" }, { @@ -20094,7 +22499,13 @@ }, { "val" : "TGMA:0001822" }, { - "val" : "UMLS:C1515976" + "val" : "UMLS:C1515976", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Structure_System_or_Substance" + } ] + } }, { "val" : "WBbt:0000100" }, { @@ -20168,7 +22579,13 @@ }, { "val" : "SCTID:181369003" }, { - "val" : "UMLS:C0042458" + "val" : "UMLS:C0042458", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Inferior_Vena_Cava" + } ] + } }, { "val" : "VHOG:0001194" }, { @@ -20224,7 +22641,13 @@ }, { "val" : "NCIT:C13283" }, { - "val" : "UMLS:C0042036" + "val" : "UMLS:C0042036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Urine" + } ] + } }, { "val" : "Wikipedia:Urine" }, { @@ -20265,7 +22688,13 @@ }, { "val" : "TAO:0005154" }, { - "val" : "UMLS:C0039097" + "val" : "UMLS:C0039097", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Synovial_Fluid" + } ] + } }, { "val" : "Wikipedia:Synovial_fluid" }, { @@ -20319,7 +22748,13 @@ }, { "val" : "SCTID:361918002" }, { - "val" : "UMLS:C0086610" + "val" : "UMLS:C0086610", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesothelium" + } ] + } }, { "val" : "Wikipedia:Mesothelium" } ], @@ -20379,7 +22814,13 @@ }, { "val" : "SCTID:116358006" }, { - "val" : "UMLS:C0035092" + "val" : "UMLS:C0035092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Vein" + } ] + } }, { "val" : "Wikipedia:Renal_vein" }, { @@ -20443,7 +22884,13 @@ }, { "val" : "SCTID:362221007" }, { - "val" : "UMLS:C0227666" + "val" : "UMLS:C0227666", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Pelvis" + } ] + } }, { "val" : "Wikipedia:Renal_pelvis" }, { @@ -20498,7 +22945,13 @@ }, { "val" : "SCTID:362211004" }, { - "val" : "UMLS:C0022655" + "val" : "UMLS:C0022655", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Cortex" + } ] + } }, { "val" : "Wikipedia:Renal_cortex" }, { @@ -20583,7 +23036,13 @@ }, { "val" : "TAO:0005281" }, { - "val" : "UMLS:C0227635" + "val" : "UMLS:C0227635", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Corpuscle" + } ] + } }, { "val" : "VHOG:0001262" }, { @@ -20678,7 +23137,13 @@ }, { "val" : "TAO:0005310" }, { - "val" : "UMLS:C0524448" + "val" : "UMLS:C0524448", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bowman_s_Capsule" + } ] + } }, { "val" : "Wikipedia:Bowman%27s_capsule" }, { @@ -20741,7 +23206,13 @@ }, { "val" : "TAO:0001287" }, { - "val" : "UMLS:C0022674" + "val" : "UMLS:C0022674", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Tubule" + } ] + } }, { "val" : "Wikipedia:Renal_tubule" }, { @@ -20864,7 +23335,13 @@ }, { "val" : "EV:0100082" }, { - "val" : "FBbt:00047153" + "val" : "FBbt:00047153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:15711" }, { @@ -20880,7 +23357,13 @@ }, { "val" : "TGMA:0001279" }, { - "val" : "UMLS:C0003461" + "val" : "UMLS:C0003461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anus" + } ] + } }, { "val" : "WBbt:0005364" }, { @@ -20963,7 +23446,13 @@ }, { "val" : "SCTID:302512001" }, { - "val" : "UMLS:C0005682" + "val" : "UMLS:C0005682", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bladder" + } ] + } }, { "val" : "VHOG:0000740" }, { @@ -21006,7 +23495,13 @@ "val" : "pelvic girdle" } ], "xrefs" : [ { - "val" : "EMAPA:37862" + "val" : "EMAPA:37862", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:16581" }, { @@ -21014,7 +23509,13 @@ }, { "val" : "SCTID:360010001" }, { - "val" : "UMLS:C0684083" + "val" : "UMLS:C0684083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pelvic_Girdle" + } ] + } }, { "val" : "VSAO:0000304" } ] @@ -21069,7 +23570,13 @@ }, { "val" : "TAO:0002153" }, { - "val" : "UMLS:C0027713" + "val" : "UMLS:C0027713", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nephron" + } ] + } }, { "val" : "Wikipedia:Nephron" }, { @@ -21146,7 +23653,13 @@ }, { "val" : "TAO:0005290" }, { - "val" : "UMLS:C1514580" + "val" : "UMLS:C1514580", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Proximal_Convoluted_Tube" + } ] + } }, { "val" : "Wikipedia:Proximal_convoluted_tubule" }, { @@ -21198,7 +23711,13 @@ }, { "val" : "SCTID:361335009" }, { - "val" : "UMLS:C0023986" + "val" : "UMLS:C0023986", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Loop_of_Henle" + } ] + } }, { "val" : "VHOG:0001270" }, { @@ -21246,7 +23765,13 @@ }, { "val" : "SCTID:245350001" }, { - "val" : "UMLS:C0227657" + "val" : "UMLS:C0227657", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Descending_Limb_of_the_Henle_s_Loop" + } ] + } }, { "val" : "Wikipedia:Descending_limb_of_loop_of_henle" } ], @@ -21361,7 +23886,13 @@ }, { "val" : "SCTID:361336005" }, { - "val" : "UMLS:C0022676" + "val" : "UMLS:C0022676", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Distal_Convoluted_Tubule" + } ] + } }, { "val" : "Wikipedia:Distal_convoluted_tubule" } ], @@ -21463,7 +23994,13 @@ }, { "val" : "SCTID:362680001" }, { - "val" : "UMLS:C0230120" + "val" : "UMLS:C0230120", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anal_Region" + } ] + } }, { "val" : "VHOG:0000395" }, { @@ -21523,7 +24060,13 @@ }, { "val" : "TAO:0000434" }, { - "val" : "UMLS:C0037253" + "val" : "UMLS:C0037253", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System" + } ] + } }, { "val" : "VHOG:0001254" }, { @@ -21575,7 +24118,13 @@ "xrefs" : [ "Wikipedia:Articular_capsule" ] } ], "xrefs" : [ { - "val" : "EMAPA:37621" + "val" : "EMAPA:37621", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:34836" }, { @@ -21591,7 +24140,13 @@ }, { "val" : "SCTID:182238002" }, { - "val" : "UMLS:C0206207" + "val" : "UMLS:C0206207", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint_Capsule" + } ] + } }, { "val" : "Wikipedia:Articular_capsule" }, { @@ -21692,13 +24247,25 @@ }, { "val" : "EMAPA:16247" }, { - "val" : "FBbt:00003125" + "val" : "FBbt:00003125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45615" }, { "val" : "MA:0000917" }, { - "val" : "MESH:D041981" + "val" : "MESH:D041981", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C34082" }, { @@ -21706,7 +24273,13 @@ }, { "val" : "TGMA:0001819" }, { - "val" : "UMLS:C0017189" + "val" : "UMLS:C0017189", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrointestinal_Tract" + } ] + } }, { "val" : "VHOG:0000309" }, { @@ -21718,10 +24291,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1371/journal.pone.0016309" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -21770,7 +24355,13 @@ "xrefs" : [ "ZFA:0005145" ] } ], "xrefs" : [ { - "val" : "EMAPA:37474" + "val" : "EMAPA:37474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100146" }, { @@ -21860,7 +24451,13 @@ }, { "val" : "TAO:0000005" }, { - "val" : "UMLS:C0003842" + "val" : "UMLS:C0003842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Artery" + } ] + } }, { "val" : "VHOG:0001251" }, { @@ -21949,7 +24546,13 @@ }, { "val" : "TAO:0000082" }, { - "val" : "UMLS:C0042449" + "val" : "UMLS:C0042449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vein" + } ] + } }, { "val" : "VHOG:0001743" }, { @@ -22044,7 +24647,13 @@ }, { "val" : "NCIT:C49215" }, { - "val" : "UMLS:C0006904" + "val" : "UMLS:C0006904", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary_Endothelium" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -22099,7 +24708,13 @@ }, { "val" : "NCIT:C13356" }, { - "val" : "UMLS:C0032105" + "val" : "UMLS:C0032105", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Plasma" + } ] + } }, { "val" : "Wikipedia:Blood_plasma" } ], @@ -22141,7 +24756,13 @@ }, { "val" : "TAO:0005315" }, { - "val" : "UMLS:C0042520" + "val" : "UMLS:C0042520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venule" + } ] + } }, { "val" : "VHOG:0001765" }, { @@ -22195,7 +24816,13 @@ }, { "val" : "TAO:0002138" }, { - "val" : "UMLS:C0003847" + "val" : "UMLS:C0003847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Arteriole" + } ] + } }, { "val" : "VHOG:0001763" }, { @@ -22278,7 +24905,13 @@ }, { "val" : "TAO:0002137" }, { - "val" : "UMLS:C0005847" + "val" : "UMLS:C0005847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel" + } ] + } }, { "val" : "VHOG:0001250" }, { @@ -22344,7 +24977,13 @@ }, { "val" : "TAO:0005250" }, { - "val" : "UMLS:C0935624" + "val" : "UMLS:C0935624", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary" + } ] + } }, { "val" : "VHOG:0001253" }, { @@ -22399,7 +25038,13 @@ }, { "val" : "SCTID:27168002" }, { - "val" : "UMLS:C0014257" + "val" : "UMLS:C0014257", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endothelium" + } ] + } }, { "val" : "galen:Endothelium" } ], @@ -22491,7 +25136,13 @@ }, { "val" : "EFO:0000461" }, { - "val" : "FBbt:00004208" + "val" : "FBbt:00004208", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69067" }, { @@ -22507,7 +25158,13 @@ }, { "val" : "TAO:0001105" }, { - "val" : "UMLS:C0013948" + "val" : "UMLS:C0013948", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Structure" + } ] + } }, { "val" : "VSAO:0000178" }, { @@ -22571,7 +25228,13 @@ }, { "val" : "SCTID:118760003" }, { - "val" : "UMLS:C0042779" + "val" : "UMLS:C0042779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Viscera" + } ] + } }, { "val" : "Wikipedia:Viscus" }, { @@ -22632,7 +25295,13 @@ }, { "val" : "SCTID:244383003" }, { - "val" : "UMLS:C0225844" + "val" : "UMLS:C0225844", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Right_Atrium" + } ] + } }, { "val" : "VHOG:0000328" }, { @@ -22725,7 +25394,13 @@ }, { "val" : "TAO:0000471" }, { - "val" : "UMLS:C0018792" + "val" : "UMLS:C0018792", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiac_Atrium" + } ] + } }, { "val" : "VHOG:0000175" }, { @@ -22768,7 +25443,13 @@ }, { "val" : "EHDAA:5049" }, { - "val" : "EMAPA:37721" + "val" : "EMAPA:37721", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71221" }, { @@ -22776,7 +25457,13 @@ }, { "val" : "MAT:0000148" }, { - "val" : "MESH:D013131" + "val" : "MESH:D013131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000148" }, { @@ -22844,7 +25531,13 @@ }, { "val" : "SCTID:322050006" }, { - "val" : "UMLS:C0222646" + "val" : "UMLS:C0222646", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Appendicular_Skeleton" + } ] + } }, { "val" : "VSAO:0000076" }, { @@ -22918,7 +25611,13 @@ }, { "val" : "TAO:0001115" }, { - "val" : "UMLS:C0460005" + "val" : "UMLS:C0460005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trunk" + } ] + } }, { "val" : "Wikipedia:Torso" }, { @@ -22966,7 +25665,13 @@ }, { "val" : "MIAA:0000119" }, { - "val" : "UMLS:C0022646" + "val" : "UMLS:C0022646", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Kidney" + } ] + } }, { "val" : "Wikipedia:Kidney" }, { @@ -23038,7 +25743,13 @@ }, { "val" : "TAO:0000151" }, { - "val" : "UMLS:C0231048" + "val" : "UMLS:C0231048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pronephros" + } ] + } }, { "val" : "VHOG:0000037" }, { @@ -23169,7 +25880,13 @@ }, { "val" : "SCTID:278858007" }, { - "val" : "UMLS:C0026860" + "val" : "UMLS:C0026860", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Musculoskeletal_System" + } ] + } }, { "val" : "VHOG:0001275" }, { @@ -23295,7 +26012,13 @@ }, { "val" : "SCTID:243949006" }, { - "val" : "UMLS:C0230139" + "val" : "UMLS:C0230139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Thoracic_Cavity" + } ] + } }, { "val" : "Wikipedia:Thoracic_cavity" } ], @@ -23346,7 +26069,13 @@ }, { "val" : "SCTID:362219002" }, { - "val" : "UMLS:C0022445" + "val" : "UMLS:C0022445", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Juxtaglomerular_Apparatus" + } ] + } }, { "val" : "Wikipedia:Juxtaglomerular_apparatus" } ], @@ -23368,7 +26097,13 @@ "xrefs" : [ { "val" : "BTO:0002494" }, { - "val" : "EMAPA:36561" + "val" : "EMAPA:36561", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:84139" }, { @@ -23376,7 +26111,13 @@ }, { "val" : "NCIT:C33101" }, { - "val" : "UMLS:C0017655" + "val" : "UMLS:C0017655", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesangium" + } ] + } }, { "val" : "Wikipedia:Mesangium" } ], @@ -23461,7 +26202,13 @@ }, { "val" : "EHDAA2:0000267" }, { - "val" : "FBbt:00005060" + "val" : "FBbt:00005060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85006" }, { @@ -23473,7 +26220,13 @@ }, { "val" : "TAO:0001438" }, { - "val" : "UMLS:C0333343" + "val" : "UMLS:C0333343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cavity" + } ] + } }, { "val" : "galen:BodyCavity" } ], @@ -23537,7 +26290,13 @@ }, { "val" : "TAO:0000135" }, { - "val" : "UMLS:C0028439" + "val" : "UMLS:C0028439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochord" + } ] + } }, { "val" : "VHOG:0000199" }, { @@ -23633,7 +26392,13 @@ }, { "val" : "TAO:0000155" }, { - "val" : "UMLS:C0376449" + "val" : "UMLS:C0376449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somite" + } ] + } }, { "val" : "VHOG:0000191" }, { @@ -23645,7 +26410,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:17237766" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somite" @@ -23682,7 +26453,13 @@ }, { "val" : "NCIT:C12957" }, { - "val" : "UMLS:C1516995" + "val" : "UMLS:C1516995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_System" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" }, { @@ -23719,7 +26496,13 @@ }, { "val" : "SCTID:244657003" }, { - "val" : "UMLS:C0227662" + "val" : "UMLS:C0227662", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Macula_Densa" + } ] + } }, { "val" : "Wikipedia:Macula_densa" } ], @@ -23779,7 +26562,13 @@ }, { "val" : "SCTID:361462002" }, { - "val" : "UMLS:C0027789" + "val" : "UMLS:C0027789", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Crest" + } ] + } }, { "val" : "VHOG:0000057" }, { @@ -23851,7 +26640,13 @@ }, { "val" : "EV:0100004" }, { - "val" : "FBbt:00001057" + "val" : "FBbt:00001057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:87657" }, { @@ -23863,7 +26658,13 @@ }, { "val" : "TAO:0001120" }, { - "val" : "UMLS:C1518271" + "val" : "UMLS:C1518271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neuroectoderm" + } ] + } }, { "val" : "VHOG:0000150" }, { @@ -23930,7 +26731,13 @@ }, { "val" : "SCTID:229765004" }, { - "val" : "UMLS:C0030797" + "val" : "UMLS:C0030797", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pelvis" + } ] + } }, { "val" : "Wikipedia:Pelvis" }, { @@ -23980,7 +26787,13 @@ }, { "val" : "SCTID:115976003" }, { - "val" : "UMLS:C0015282" + "val" : "UMLS:C0015282", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" } ], @@ -24043,7 +26856,13 @@ }, { "val" : "TAO:0001641" }, { - "val" : "UMLS:C0009780" + "val" : "UMLS:C0009780", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Connective_Tissue" + } ] + } }, { "val" : "VSAO:0000017" }, { @@ -24111,7 +26930,13 @@ }, { "val" : "SCTID:91727004" }, { - "val" : "UMLS:C2328219" + "val" : "UMLS:C2328219", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle_Tissue" + } ] + } }, { "val" : "Wikipedia:Muscle_tissue" }, { @@ -24189,7 +27014,13 @@ }, { "val" : "TAO:0005023" }, { - "val" : "UMLS:C0018957" + "val" : "UMLS:C0018957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hematopoietic_System" + } ] + } }, { "val" : "VHOG:0001624" }, { @@ -24288,7 +27119,13 @@ }, { "val" : "EMAPA:18425" }, { - "val" : "FBbt:00100317" + "val" : "FBbt:00100317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7146" }, { @@ -24306,7 +27143,13 @@ }, { "val" : "SCTID:134358001" }, { - "val" : "UMLS:C1285092" + "val" : "UMLS:C1285092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gland" + } ] + } }, { "val" : "Wikipedia:Gland" }, { @@ -24394,7 +27237,13 @@ "xrefs" : [ { "val" : "BIRNLEX:1011" }, { - "val" : "EMAPA:37442" + "val" : "EMAPA:37442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67552" }, { @@ -24501,7 +27350,13 @@ }, { "val" : "TAO:0000150" }, { - "val" : "UMLS:C1283945" + "val" : "UMLS:C1283945", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pronephric_Duct" + } ] + } }, { "val" : "Wikipedia:Pronephric_duct" }, { @@ -24556,7 +27411,13 @@ }, { "val" : "TE:E5.11.2.0.0.0.4" }, { - "val" : "UMLS:C1511224" + "val" : "UMLS:C1511224", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Island" + } ] + } }, { "val" : "VHOG:0000085" }, { @@ -24617,7 +27478,13 @@ }, { "val" : "TAO:0001206" }, { - "val" : "UMLS:C1284010" + "val" : "UMLS:C1284010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intermediate_Mesoderm" + } ] + } }, { "val" : "VHOG:0000087" }, { @@ -24721,7 +27588,13 @@ }, { "val" : "TAO:0000546" }, { - "val" : "UMLS:C0043204" + "val" : "UMLS:C0043204", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesonephric_Duct" + } ] + } }, { "val" : "Wikipedia:Mesonephric_duct" }, { @@ -24785,7 +27658,13 @@ }, { "val" : "TAO:0000132" }, { - "val" : "UMLS:C0920623" + "val" : "UMLS:C0920623", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Plate" + } ] + } }, { "val" : "VHOG:0000068" }, { @@ -24846,7 +27725,13 @@ }, { "val" : "TAO:0000255" }, { - "val" : "UMLS:C1284009" + "val" : "UMLS:C1284009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Paraxial_Mesoderm" + } ] + } }, { "val" : "VHOG:0000114" }, { @@ -24913,7 +27798,13 @@ }, { "val" : "TAO:0000121" }, { - "val" : "UMLS:C1517749" + "val" : "UMLS:C1517749", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lateral_Mesoderm" + } ] + } }, { "val" : "VHOG:0000118" }, { @@ -24958,7 +27849,13 @@ }, { "val" : "TAO:0000028" }, { - "val" : "UMLS:C1514450" + "val" : "UMLS:C1514450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium_of_the_Heart" + } ] + } }, { "val" : "XAO:0000336" }, { @@ -25008,7 +27905,13 @@ }, { "val" : "TAO:0001080" }, { - "val" : "UMLS:C0183176" + "val" : "UMLS:C0183176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclerotome" + } ] + } }, { "val" : "VHOG:0000680" }, { @@ -25115,7 +28018,13 @@ }, { "val" : "TAO:0000393" }, { - "val" : "UMLS:C0162415" + "val" : "UMLS:C0162415", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesenchyme" + } ] + } }, { "val" : "VHOG:0000170" }, { @@ -25161,7 +28070,13 @@ "val" : "genitalia" } ], "xrefs" : [ { - "val" : "EMAPA:37731" + "val" : "EMAPA:37731", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0001752" }, { @@ -25173,7 +28088,13 @@ }, { "val" : "TGMA:0000591" }, { - "val" : "UMLS:C0017420" + "val" : "UMLS:C0017420", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Genitalia" + } ] + } }, { "val" : "WBbt:0008422" } ], @@ -25275,7 +28196,13 @@ "xrefs" : [ "OBOL:automatic" ] } ], "xrefs" : [ { - "val" : "EMAPA:37242" + "val" : "EMAPA:37242", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0001903" } ], @@ -25350,7 +28277,13 @@ "xrefs" : [ "OBOL:automatic" ] } ], "xrefs" : [ { - "val" : "EMAPA:37237" + "val" : "EMAPA:37237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000511" } ], @@ -25437,7 +28370,13 @@ "xrefs" : [ "OBOL:automatic" ] } ], "xrefs" : [ { - "val" : "EMAPA:37240" + "val" : "EMAPA:37240", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000554" } ], @@ -25533,7 +28472,13 @@ "xrefs" : [ "OBOL:automatic" ] } ], "xrefs" : [ { - "val" : "EMAPA:37057" + "val" : "EMAPA:37057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000524" } ], @@ -25586,7 +28531,13 @@ }, { "val" : "NCIT:C34195" }, { - "val" : "UMLS:C1512940" + "val" : "UMLS:C1512940", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intraembryonic_Coelom" + } ] + } }, { "val" : "VHOG:0000316" }, { @@ -25619,7 +28570,13 @@ }, { "val" : "NCIT:C67387" }, { - "val" : "UMLS:C0927195" + "val" : "UMLS:C0927195", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stroma_Connective_Tissue" + } ] + } } ] } }, { @@ -25640,7 +28597,13 @@ }, { "val" : "EHDAA2:0003114" }, { - "val" : "FBbt:00007474" + "val" : "FBbt:00007474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -25739,7 +28702,13 @@ }, { "val" : "SCTID:244405007" }, { - "val" : "UMLS:C0042460" + "val" : "UMLS:C0042460", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vena_Cava" + } ] + } }, { "val" : "Wikipedia:Venae_cavae" } ], @@ -25954,7 +28923,13 @@ }, { "val" : "SCTID:278861008" }, { - "val" : "UMLS:C0042066" + "val" : "UMLS:C0042066", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Genitourinary_System" + } ] + } }, { "val" : "VHOG:0000286" }, { @@ -26442,9 +29417,21 @@ }, { "val" : "SCTID:361328001" }, { - "val" : "UMLS:C0227629" - }, { - "val" : "UMLS:C1514613" + "val" : "UMLS:C0227629", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Pyramid" + } ] + } + }, { + "val" : "UMLS:C1514613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pyramid_of_Malpighi" + } ] + } }, { "val" : "Wikipedia:Renal_pyramids" } ], @@ -26634,7 +29621,13 @@ }, { "val" : "TAO:0005284" }, { - "val" : "UMLS:C0226356" + "val" : "UMLS:C0226356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Glomerular_Capillary" + } ] + } }, { "val" : "ZFA:0005284" } ], @@ -26758,7 +29751,13 @@ }, { "val" : "SCTID:361438007" }, { - "val" : "UMLS:C0033153" + "val" : "UMLS:C0033153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primitive_Streak" + } ] + } }, { "val" : "VHOG:0001202" }, { @@ -26823,7 +29822,13 @@ }, { "val" : "TAO:0000010" }, { - "val" : "UMLS:C0007226" + "val" : "UMLS:C0007226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiovascular_System" + } ] + } }, { "val" : "VHOG:0000302" }, { @@ -26949,7 +29954,13 @@ }, { "val" : "SCTID:362060003" }, { - "val" : "UMLS:C1267406" + "val" : "UMLS:C1267406", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venous_System" + } ] + } }, { "val" : "VHOG:0000277" } ], @@ -26981,7 +29992,13 @@ }, { "val" : "TAO:0005257" }, { - "val" : "UMLS:C1706972" + "val" : "UMLS:C1706972", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel_Endothelium" + } ] + } }, { "val" : "ZFA:0005257" } ], @@ -27081,7 +30098,13 @@ }, { "val" : "NCIT:C34131" }, { - "val" : "UMLS:C1516779" + "val" : "UMLS:C1516779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conceptus" + } ] + } }, { "val" : "Wikipedia:Conceptus" } ], @@ -27145,7 +30168,13 @@ }, { "val" : "SCTID:76147008" }, { - "val" : "UMLS:C1512856" + "val" : "UMLS:C1512856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Interlobular_Artery" + } ] + } }, { "val" : "Wikipedia:Interlobular_arteries" } ], @@ -27209,7 +30238,13 @@ }, { "val" : "BTO:0001403" }, { - "val" : "FBbt:00005317" + "val" : "FBbt:00005317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:293108" }, { @@ -27223,9 +30258,21 @@ }, { "val" : "NCIT:C34058" }, { - "val" : "UMLS:C0017199" - }, { - "val" : "UMLS:C1284022" + "val" : "UMLS:C0017199", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrula" + } ] + } + }, { + "val" : "UMLS:C1284022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trilaminar_Embryonic_Disc" + } ] + } }, { "val" : "Wikipedia:Gastrula" }, { @@ -27329,7 +30376,13 @@ }, { "val" : "NCIT:C49276" }, { - "val" : "UMLS:C1709902" + "val" : "UMLS:C1709902", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Tubule_Epithelium" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -27409,7 +30462,13 @@ }, { "val" : "TAO:0002171" }, { - "val" : "UMLS:C0014261" + "val" : "UMLS:C0014261", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_Endothelium" + } ] + } }, { "val" : "VHOG:0001217" }, { @@ -27483,7 +30542,13 @@ }, { "val" : "NCIT:C34301" }, { - "val" : "UMLS:C1519423" + "val" : "UMLS:C1519423", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somatopleure" + } ] + } }, { "val" : "VHOG:0000557" }, { @@ -27520,7 +30585,13 @@ }, { "val" : "SCTID:361405003" }, { - "val" : "UMLS:C1283944" + "val" : "UMLS:C1283944", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nephrogenic_Cord" + } ] + } }, { "val" : "Wikipedia:Nephrogenic_cord" } ] @@ -27614,7 +30685,13 @@ "val" : "joint" } ], "xrefs" : [ { - "val" : "FBbt:00005811" + "val" : "FBbt:00005811", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -27651,7 +30728,13 @@ "xrefs" : [ "FMA:71131" ] } ], "xrefs" : [ { - "val" : "FBbt:00100315" + "val" : "FBbt:00100315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:71131" } ], @@ -27704,7 +30787,13 @@ }, { "val" : "SCTID:361463007" }, { - "val" : "UMLS:C0814992" + "val" : "UMLS:C0814992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Groove" + } ] + } }, { "val" : "Wikipedia:Neural_groove" }, { @@ -27741,7 +30830,13 @@ }, { "val" : "SCTID:361461009" }, { - "val" : "UMLS:C0814993" + "val" : "UMLS:C0814993", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Fold" + } ] + } }, { "val" : "Wikipedia:Neural_fold" }, { @@ -28042,7 +31137,13 @@ }, { "val" : "SCTID:245434005" }, { - "val" : "UMLS:C0227658" + "val" : "UMLS:C0227658", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ascending_Limb_of_the_Henle_s_Loop" + } ] + } }, { "val" : "Wikipedia:Ascending_limb_of_loop_of_Henle" } ], @@ -28158,7 +31259,13 @@ "xrefs" : [ "MA:0000529" ] } ], "xrefs" : [ { - "val" : "EMAPA:37062" + "val" : "EMAPA:37062", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000529" } ], @@ -28183,7 +31290,13 @@ "xrefs" : [ "MA:0000516" ] } ], "xrefs" : [ { - "val" : "EMAPA:37270" + "val" : "EMAPA:37270", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000516" } ], @@ -28208,7 +31321,13 @@ "xrefs" : [ "MA:0000557" ] } ], "xrefs" : [ { - "val" : "EMAPA:37273" + "val" : "EMAPA:37273", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000557" } ], @@ -28239,7 +31358,13 @@ "val" : "pelvis region organ" } ], "xrefs" : [ { - "val" : "EMAPA:37275" + "val" : "EMAPA:37275", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000543" } ] @@ -28260,7 +31385,13 @@ "xrefs" : [ "MA:0000563" ] } ], "xrefs" : [ { - "val" : "EMAPA:37271" + "val" : "EMAPA:37271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000563" } ], @@ -28434,7 +31565,13 @@ }, { "val" : "EHDAA2:0003125" }, { - "val" : "FBbt:00007006" + "val" : "FBbt:00007006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:292313" }, { @@ -28713,13 +31850,25 @@ }, { "val" : "SCTID:68989006" }, { - "val" : "UMLS:C0004799" + "val" : "UMLS:C0004799", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Basement_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "http://palaeos.com/metazoa/porifera/homoscleromorpha.html" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "basement membrane of epithelium" @@ -28763,7 +31912,13 @@ }, { "val" : "TAO:0005285" }, { - "val" : "UMLS:C0599297" + "val" : "UMLS:C0599297", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Glomerular_Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Glomerular_basement_membrane" }, { @@ -28855,7 +32010,13 @@ }, { "val" : "SCTID:361725000" }, { - "val" : "UMLS:C0222645" + "val" : "UMLS:C0222645", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Axial_Skeleton" + } ] + } }, { "val" : "VSAO:0000056" }, { @@ -28914,7 +32075,13 @@ }, { "val" : "SCTID:308826008" }, { - "val" : "UMLS:C0231056" + "val" : "UMLS:C0231056", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cloacal_Membrane" + } ] + } }, { "val" : "VHOG:0001198" }, { @@ -28944,7 +32111,13 @@ }, { "val" : "NCIT:C34231" }, { - "val" : "UMLS:C1518429" + "val" : "UMLS:C1518429", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Plate" + } ] + } }, { "val" : "VHOG:0001212" } ], @@ -28985,7 +32158,13 @@ }, { "val" : "NCIT:C34232" }, { - "val" : "UMLS:C1518430" + "val" : "UMLS:C1518430", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Process" + } ] + } }, { "val" : "VHOG:0001213" } ], @@ -29015,7 +32194,13 @@ "xrefs" : [ { "val" : "BIRNLEX:20" }, { - "val" : "EMAPA:37441" + "val" : "EMAPA:37441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:280556" }, { @@ -29059,7 +32244,13 @@ }, { "val" : "SCTID:361333002" }, { - "val" : "UMLS:C1707510" + "val" : "UMLS:C1707510", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Convoluted_Tubule" + } ] + } }, { "val" : "Wikipedia:Convoluted_tubule" } ] @@ -29310,7 +32501,13 @@ "val" : "terminal section of digestive tract" } ], "xrefs" : [ { - "val" : "FBbt:00005756" + "val" : "FBbt:00005756", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "WBbt:0005773" } ], @@ -29362,7 +32559,13 @@ }, { "val" : "SCTID:40118003" }, { - "val" : "UMLS:C0221909" + "val" : "UMLS:C0221909", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Squamous_epithelium" } ], @@ -29415,7 +32618,13 @@ }, { "val" : "NCIT:C34022" }, { - "val" : "UMLS:C1515977" + "val" : "UMLS:C1515977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Surface" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -29534,7 +32743,13 @@ }, { "val" : "SCTID:360394002" }, { - "val" : "UMLS:C1514442" + "val" : "UMLS:C1514442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordial_Gut" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -29973,7 +33188,13 @@ }, { "val" : "EHDAA2:0003170" }, { - "val" : "FBbt:00005426" + "val" : "FBbt:00005426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "Wikipedia:Anlage_(biology)" } ], @@ -30060,7 +33281,13 @@ }, { "val" : "NCIT:C33854" }, { - "val" : "UMLS:C0489903" + "val" : "UMLS:C0489903", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_System" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -30106,7 +33333,13 @@ "val" : "limb girdle region" } ], "xrefs" : [ { - "val" : "EMAPA:37854" + "val" : "EMAPA:37854", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:24874" }, { @@ -30250,7 +33483,13 @@ "val" : "straight tubule" } ], "xrefs" : [ { - "val" : "EMAPA:37489" + "val" : "EMAPA:37489", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002634" }, { @@ -30496,7 +33735,13 @@ "xrefs" : [ "FMA:71637" ] } ], "xrefs" : [ { - "val" : "EMAPA:37091" + "val" : "EMAPA:37091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71637" }, { @@ -30574,7 +33819,13 @@ }, { "val" : "NCIT:C32894" }, { - "val" : "UMLS:C0736382" + "val" : "UMLS:C0736382", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Kidney_Lower_Lobe" + } ] + } }, { "val" : "Wikipedia:Renal_lobe" } ], @@ -30604,7 +33855,13 @@ "xrefs" : [ { "val" : "CARO:0010000" }, { - "val" : "FBbt:00100313" + "val" : "FBbt:00100313", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -30826,7 +34083,13 @@ "xrefs" : [ "FMA:7182" ] } ], "xrefs" : [ { - "val" : "EMAPA:37858" + "val" : "EMAPA:37858", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:7182" }, { @@ -30884,7 +34147,13 @@ "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] } ], "xrefs" : [ { - "val" : "EMAPA:37863" + "val" : "EMAPA:37863", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:7184" }, { @@ -31055,7 +34324,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007330" + "val" : "FBbt:00007330", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67509" }, { @@ -31143,7 +34418,13 @@ "val" : "main body segment" } ], "xrefs" : [ { - "val" : "FBbt:00057001" + "val" : "FBbt:00057001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -31198,7 +34479,13 @@ }, { "val" : "NCIT:C32450" }, { - "val" : "UMLS:C1511770" + "val" : "UMLS:C1511770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Dense_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Dense_connective_tissue" } ], @@ -31289,7 +34576,13 @@ "val" : "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "coelom" @@ -31730,7 +35023,13 @@ "xrefs" : [ "MA:0002449" ] } ], "xrefs" : [ { - "val" : "EMAPA:37597" + "val" : "EMAPA:37597", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002449" } ], @@ -31928,7 +35227,13 @@ "xrefs" : [ { "val" : "CARO:0020000" }, { - "val" : "FBbt:00007276" + "val" : "FBbt:00007276", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -32193,7 +35498,13 @@ "comments" : [ "It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however, most visceral muscles in arthropods are actually striated." ], "synonyms" : [ { "pred" : "hasExactSynonym", - "val" : "visceral muscle" + "val" : "visceral muscle", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "BTO:0002780" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -33842,7 +37153,13 @@ "meta" : { "definition" : { "val" : "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -33858,7 +37175,13 @@ "meta" : { "definition" : { "val" : "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -34265,7 +37588,7 @@ } }, { "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym", - "lbl" : "has_narrow_synonym", + "lbl" : "has narrow synonym", "type" : "PROPERTY", "propertyType" : "ANNOTATION", "meta" : { @@ -34384,22 +37707,18 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000007", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0002321" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0011115" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", - "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0017145" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000037", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000037", "pred" : "is_a", @@ -34590,6 +37909,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000076", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000066" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000076", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000077", "pred" : "is_a", @@ -34822,6 +38145,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000219" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000333", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", @@ -35316,6 +38643,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000669", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0008034" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000680", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000680", "pred" : "is_a", @@ -35766,6 +39097,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0002653", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000115" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0002653", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0002681", "pred" : "is_a", @@ -35786,6 +39121,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0007004", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", @@ -35846,10 +39185,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0011026", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", @@ -36420,14 +39755,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0001841", "pred" : "http://purl.obolibrary.org/obo/RO_0002297", "obj" : "http://purl.obolibrary.org/obo/UBERON_0001049" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0001977", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0003071" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0001977", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", - "obj" : "http://purl.obolibrary.org/obo/GO_0050878" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0001990", "pred" : "is_a", @@ -36560,10 +39887,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0003091", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/GO_0050891" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0003093", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0001977" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0003093", "pred" : "is_a", @@ -36626,7 +39949,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0032991" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005581", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "pred" : "http://purl.obolibrary.org/obo/RO_0002160", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005587", @@ -37028,6 +40351,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008104", "pred" : "http://purl.obolibrary.org/obo/RO_0004009", "obj" : "http://purl.obolibrary.org/obo/PR_000000001" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0008150", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", + "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -37199,15 +40526,15 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0015031", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0008104" + "obj" : "http://purl.obolibrary.org/obo/GO_0006810" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0015031", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0045184" + "obj" : "http://purl.obolibrary.org/obo/GO_0008104" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0015031", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0071705" + "obj" : "http://purl.obolibrary.org/obo/GO_0045184" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0015669", "pred" : "is_a", @@ -38292,14 +41619,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0071692", "pred" : "http://purl.obolibrary.org/obo/RO_0004009", "obj" : "http://purl.obolibrary.org/obo/PR_000000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0071705", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/BFO_0000003" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0071705", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0006810" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0071826", "pred" : "is_a", @@ -38744,6 +42063,10 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33154" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "pred" : "is_a", @@ -38940,6 +42263,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0001579", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0001591", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0000052" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0001690", "pred" : "is_a", @@ -39024,6 +42351,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002198", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0002254", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001591" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002266", "pred" : "is_a", @@ -46828,6 +50159,13 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0001981" } ] + }, { + "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000076", + "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], + "restrictions" : [ { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002254" + } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000081", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -49659,6 +52997,13 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" } ] + }, { + "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", + "allValuesFromEdges" : [ { + "sub" : "http://purl.obolibrary.org/obo/GO_0005581", + "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062", "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], diff --git a/src/ontology/subsets/kidney_upper_slim.obo b/src/ontology/subsets/kidney_upper_slim.obo index 8ecd0630b..b7225a1f3 100644 --- a/src/ontology/subsets/kidney_upper_slim.obo +++ b/src/ontology/subsets/kidney_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2025-12-17/subsets/kidney_upper_slim.owl +data-version: cl/releases/2026-03-17/subsets/kidney_upper_slim.owl idspace: dc http://purl.org/dc/elements/1.1/ idspace: foaf http://xmlns.com/foaf/0.1/ idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# @@ -7,7 +7,7 @@ idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: terms http://purl.org/dc/terms/ ontology: cl/subsets/kidney_upper_slim -property_value: owl:versionInfo "2025-12-17" xsd:string +property_value: owl:versionInfo "2026-03-17" xsd:string [Term] id: BFO:0000002 @@ -78,21 +78,18 @@ property_value: skos:prefLabel "early embryonic cell (metazoa)" xsd:string id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] -comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset -synonym: "animal stem cell" EXACT [] +synonym: "animal stem cell" NARROW [] xref: CALOHA:TS-2086 xref: FMA:63368 xref: ZFA:0005957 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa relationship: RO:0002215 GO:0017145 ! capable of stem cell division property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000034" xsd:string {name="stem cell on CELLxGENE CellGuide"} @@ -119,6 +116,7 @@ xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 xref: ZFA:0009014 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell @@ -396,13 +394,18 @@ property_value: skos:prefLabel "columnar/cuboidal epithelial cell" xsd:string [Term] id: CL:0000076 name: squamous epithelial cell +def: "An epithelial cell that has a flattened morphology." [] subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: CALOHA:TS-1249 xref: ZFA:0009039 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell +intersection_of: CL:0000066 ! epithelial cell +intersection_of: RO:0000053 PATO:0002254 ! has characteristic flattened +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: skos:prefLabel "squamous epithelial cell" xsd:string +property_value: terms:date "2025-12-16T15:56:39Z" xsd:dateTime [Term] id: CL:0000077 @@ -554,6 +557,7 @@ name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset subset: general_cell_types_upper_slim +subset: human_reference_atlas subset: human_subset subset: mouse_subset synonym: "muscle fiber" EXACT [] @@ -571,6 +575,7 @@ is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell relationship: RO:0002202 CL:0000056 ! develops from myoblast property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI +property_value: RO:0002175 NCBITaxon:9606 property_value: skos:prefLabel "muscle cell" xsd:string [Term] @@ -759,6 +764,7 @@ subset: mouse_subset xref: FMA:86667 xref: ZFA:0007086 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell @@ -1271,6 +1277,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009291 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell @@ -1799,6 +1806,7 @@ def: "A squamous shaped endothelial cell." [GOC:dos] subset: human_subset subset: mouse_subset is_a: CL:0000115 ! endothelial cell +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: terms:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T03:31:25Z @@ -1837,6 +1845,7 @@ subset: human_subset subset: mouse_subset xref: ZFA:0007084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: BFO:0000002 +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell @@ -1940,7 +1949,6 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset is_a: BFO:0000002 -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002202 CL:0000034 ! develops from stem cell @@ -2475,6 +2483,7 @@ is_a: GO:0140096 ! catalytic activity, acting on a protein is_a: GO:0140101 ! catalytic activity, acting on a tRNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0000262 @@ -2661,21 +2670,6 @@ intersection_of: RO:0002297 UBERON:0001049 ! results in formation of anatomical relationship: BFO:0000050 GO:0021915 ! part of neural tube development relationship: RO:0002297 UBERON:0001049 ! results in formation of anatomical entity neural tube -[Term] -id: GO:0001977 -name: renal system process involved in regulation of blood volume -namespace: biological_process -def: "A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system." [GOC:dph, GOC:tb, ISBN:0721643949] -subset: gocheck_obsoletion_candidate -synonym: "renal blood volume control of blood pressure" RELATED [] -synonym: "renal regulation of blood volume" RELATED [GOC:dph, GOC:tb] -is_a: GO:0003071 ! renal system process involved in regulation of systemic arterial blood pressure -relationship: BFO:0000050 GO:0050878 ! part of regulation of body fluid levels -property_value: RO:0002161 NCBITaxon:2 -property_value: RO:0002161 NCBITaxon:2157 -property_value: RO:0002161 NCBITaxon:4896 -property_value: RO:0002161 NCBITaxon:4932 - [Term] id: GO:0001990 name: regulation of systemic arterial blood pressure by hormone @@ -2931,7 +2925,6 @@ id: GO:0003093 name: regulation of glomerular filtration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule." [GOC:mtg_cardio] -is_a: GO:0001977 ! renal system process involved in regulation of blood volume is_a: GO:0098801 ! regulation of renal system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003094 ! regulates glomerular filtration @@ -2987,6 +2980,7 @@ subset: goslim_yeast synonym: "molecular function" EXACT [] disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process +property_value: IAO:0000116 "This is the same as GO molecular function" xsd:string [Term] id: GO:0003824 @@ -3023,6 +3017,9 @@ synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 +union_of: GO:0032991 ! protein-containing complex +union_of: GO:0044423 ! virion component +union_of: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0008150 ! biological_process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI @@ -3071,7 +3068,8 @@ namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa +relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa +relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0005587 @@ -3856,6 +3854,7 @@ synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process +relationship: BFO:0000051 GO:0003674 ! has part molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI creation_date: 2012-09-19T15:05:24Z @@ -4211,9 +4210,9 @@ subset: goslim_chembl subset: goslim_pir subset: goslim_yeast synonym: "enzyme transport" NARROW [] +is_a: GO:0006810 ! transport is_a: GO:0008104 ! intracellular protein localization is_a: GO:0045184 ! establishment of protein localization -is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 PR:000000001 ! has primary input protein @@ -4347,10 +4346,10 @@ subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" -xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016746 @@ -4367,6 +4366,7 @@ xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurin xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" is_a: GO:0016740 ! transferase activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016755 @@ -4376,6 +4376,7 @@ def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) synonym: "transferase activity, transferring amino-acyl groups" EXACT [] xref: EC:2.3.2.- is_a: GO:0016746 ! acyltransferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0017145 @@ -4603,6 +4604,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] @@ -4611,6 +4613,7 @@ is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] @@ -4618,6 +4621,7 @@ id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:18391171] +subset: gocheck_do_not_annotate synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly @@ -4625,6 +4629,7 @@ is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI [Term] id: GO:0030054 @@ -4922,6 +4927,7 @@ is_a: GO:0005575 ! cellular_component disjoint_from: GO:0044423 ! virion component disjoint_from: GO:0110165 ! cellular anatomical structure relationship: BFO:0000051 PR:000000001 ! has part protein +property_value: IAO:0000116 "This is not covalently bonded, which conflicts with changes to the parent definition." xsd:string [Term] id: GO:0033036 @@ -5070,7 +5076,7 @@ relationship: BFO:0000051 GO:0034220 ! has part monoatomic ion transmembrane tra id: GO:0042592 name: homeostatic process namespace: biological_process -def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] +def: "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." [PMID:26265027] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse @@ -5081,6 +5087,7 @@ synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological_process +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31175" xsd:anyURI [Term] id: GO:0042644 @@ -5147,6 +5154,7 @@ id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon @@ -5159,6 +5167,7 @@ synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: BFO:0000050 CL:0000000 ! part of cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: skos:prefLabel "cell projection" xsd:string [Term] @@ -6114,16 +6123,6 @@ relationship: RO:0002339 GO:0005576 ! has target end location extracellular regi relationship: RO:0004009 PR:000000001 ! has primary input protein creation_date: 2010-02-25T04:00:13Z -[Term] -id: GO:0071705 -name: nitrogen compound transport -namespace: biological_process -def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] -subset: gocheck_obsoletion_candidate -is_a: BFO:0000003 -is_a: GO:0006810 ! transport -creation_date: 2010-03-08T03:56:28Z - [Term] id: GO:0071826 name: protein-RNA complex organization @@ -6300,15 +6299,16 @@ def: "A collagen trimer that forms networks." [PMID:21421911] is_a: BFO:0000004 is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer -intersection_of: BFO:0000050 GO:0098645 ! part of collagen network -relationship: BFO:0000050 GO:0098645 ! part of collagen network +intersection_of: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens +relationship: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens [Term] id: GO:0098643 -name: fibrillar collagen +name: fibrillar collagen complex namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175] synonym: "banded collagen fibril" EXACT [] +synonym: "fibrillar collagen" EXACT [] is_a: GO:0098644 ! complex of collagen trimers relationship: BFO:0000050 GO:0140152 ! part of collagenous component of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI @@ -6329,10 +6329,12 @@ property_value: skos:prefLabel "complex of collagen trimers" xsd:string [Term] id: GO:0098645 -name: collagen network +name: complex of network-forming collagens namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] +synonym: "collagen network" EXACT [] is_a: GO:0098644 ! complex of collagen trimers +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30938" xsd:anyURI [Term] id: GO:0098793 @@ -6434,6 +6436,8 @@ subset: goslim_pir synonym: "cellular anatomical entity" EXACT [] is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure +property_value: IAO:0000116 "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." xsd:string +property_value: IAO:0000116 "Overlaps with some cellular components from GO" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28978" xsd:anyURI @@ -6588,7 +6592,7 @@ id: GO:0140154 name: chicken-wire-like collagen network namespace: cellular_component def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942] -is_a: GO:0098645 ! collagen network +is_a: GO:0098645 ! complex of network-forming collagens relationship: BFO:0000050 GO:0140143 ! part of collagenous component of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI @@ -6859,6 +6863,22 @@ xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: skos:prefLabel "Eukaryota" xsd:string +[Term] +id: NCBITaxon:28009 +name: Choanoflagellata +namespace: ncbi_taxonomy +synonym: "Choanoflagellatea" RELATED synonym [] +synonym: "choanoflagellates" EXACT genbank_common_name [] +synonym: "choanoflagellates" RELATED blast_name [] +synonym: "Choanoflagellida" RELATED synonym [] +synonym: "Choanomonada" RELATED synonym [] +synonym: "Choanozoa" RELATED synonym [] +xref: GC_ID:1 +xref: PMID:27765632 +is_a: NCBITaxon:33154 ! Opisthokonta +disjoint_from: NCBITaxon:33208 ! Metazoa +disjoint_from: NCBITaxon:4751 ! Fungi + [Term] id: NCBITaxon:314146 name: Euarchontoglires @@ -7344,6 +7364,14 @@ subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality +[Term] +id: PATO:0001591 +name: curvature +namespace: quality +def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] +subset: attribute_slim +is_a: PATO:0000052 ! shape + [Term] id: PATO:0001690 name: contractile @@ -7531,6 +7559,18 @@ is_a: PATO:0001018 ! physical quality property_value: terms:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-03-15T04:35:27Z +[Term] +id: PATO:0002254 +name: flattened +namespace: quality +def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] +comment: Becoming flat but not necessarily completely flat. +subset: value_slim +synonym: "compressed" RELATED [] +is_a: PATO:0001591 ! curvature +property_value: terms:contributor https://orcid.org/0000-0002-2061-091X +creation_date: 2010-08-16T03:59:34Z + [Term] id: PATO:0002266 name: 3-D shape @@ -17003,7 +17043,7 @@ xref: NCIT:C32339 xref: NIF_Subcellular:sao7547390221 is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: RO:0002473 GO:0005581 ! composed primarily of collagen trimer -relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen +relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen complex property_value: seeAlso UBERON:0007377 property_value: skos:prefLabel "collection of collagen fibrils" xsd:string diff --git a/src/ontology/subsets/kidney_upper_slim.owl b/src/ontology/subsets/kidney_upper_slim.owl index 2832aef43..b4482195b 100644 --- a/src/ontology/subsets/kidney_upper_slim.owl +++ b/src/ontology/subsets/kidney_upper_slim.owl @@ -14,8 +14,8 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - - 2025-12-17 + + 2026-03-17 @@ -251,7 +251,6 @@ WHERE { An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has narrow synonym - has_narrow_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/19 @@ -2774,14 +2773,7 @@ Each of these 3 primitives can be composed to yield a cross-product of different - - - - - - - @@ -2798,13 +2790,12 @@ Stem cells have numerous potential applications in medicine, including the treat CALOHA:TS-2086 FMA:63368 ZFA:0005957 - animal stem cell + animal stem cell - This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. stem cell https://cellxgene.cziscience.com/cellguide/CL_0000034 stem cell @@ -2911,6 +2902,7 @@ Stem cells have numerous potential applications in medicine, including the treat + @@ -3817,7 +3809,26 @@ Blood vessel endothelial cells are sensitive to various stimuli, including shear + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -4285,6 +4296,7 @@ Apart from their role in tissue maintenance and repair, MSCs are integral to the A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -4298,6 +4310,7 @@ Apart from their role in tissue maintenance and repair, MSCs are integral to the + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -4859,6 +4872,7 @@ In addition to their role in oxygen transport, erythrocytes also play a key role + @@ -6670,6 +6684,7 @@ Furthermore, pericytes have demonstrated functions in regulating immune and infl + @@ -8275,6 +8290,12 @@ The balance between cell proliferation and differentiation in embryonic cells is + + + + + + A squamous shaped endothelial cell. 2011-07-08T03:31:25Z @@ -8377,6 +8398,7 @@ Renal principal cells are also involved in the regulation of sodium and potassiu + @@ -8660,7 +8682,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -10287,6 +10308,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. https://github.com/geneontology/go-ontology/issues/22192 https://github.com/geneontology/go-ontology/issues/25493 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.12 MetaCyc:PEPTIDYLTRANSFERASE-RXN Reactome:R-HSA-156912 @@ -10880,46 +10902,6 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - - - - - - - - - A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system. - - - - - biological_process - renal blood volume control of blood pressure - renal regulation of blood volume - GO:0001977 - - renal system process involved in regulation of blood volume - - - - - A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system. - GOC:dph - GOC:tb - ISBN:0721643949 - - - - - renal regulation of blood volume - GOC:dph - GOC:tb - - - - @@ -11548,7 +11530,6 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - @@ -11668,6 +11649,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. + This is the same as GO molecular function molecular function molecular_function GO:0003674 @@ -11730,6 +11712,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + @@ -11849,10 +11840,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component @@ -13805,6 +13802,12 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. https://github.com/geneontology/go-ontology/issues/24968 2012-09-19T15:05:24Z @@ -14082,6 +14085,30 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + + + + + + + + + + + + + + + A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. @@ -14130,6 +14157,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + @@ -14200,6 +14237,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + @@ -14270,6 +14317,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + @@ -14306,6 +14363,70 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. @@ -14747,9 +14868,9 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + - The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. enzyme transport biological_process @@ -15051,10 +15172,10 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + https://github.com/geneontology/go-ontology/issues/30193 EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 - Reactome:R-HSA-5333607 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function @@ -15089,12 +15210,6 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 - - - - Reactome:R-HSA-5333607 - GSSeH combines with bGalNAc derivative to form GSSebGalNac - @@ -15116,6 +15231,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 @@ -15166,6 +15282,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function @@ -15808,12 +15925,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 https://github.com/geneontology/go-ontology/issues/26279 cell projection organisation biological_process cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 + cell projection organization @@ -15863,10 +15982,12 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 formation of a cell surface projection biological_process cell projection biogenesis GO:0030031 + cell projection assembly @@ -16668,6 +16789,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + This is not covalently bonded, which conflicts with changes to the parent definition. macromolecular complex macromolecule complex protein containing complex @@ -17196,7 +17318,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - Any biological process involved in the maintenance of an internal steady state. + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + https://github.com/geneontology/go-ontology/issues/31175 homeostasis activation of homeostatic process inhibition of homeostatic process @@ -17213,9 +17336,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - Any biological process involved in the maintenance of an internal steady state. - GOC:jl - ISBN:0395825172 + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + PMID:26265027 @@ -17323,6 +17445,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + @@ -17431,11 +17563,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 cell process cellular process cellular projection cellular_component GO:0042995 + @@ -20013,27 +20147,6 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - - - - The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. - 2010-03-08T03:56:28Z - biological_process - GO:0071705 - - nitrogen compound transport - - - - - The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. - GOC:mah - - - - @@ -20572,9 +20685,10 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://github.com/geneontology/go-ontology/issues/29474 https://github.com/geneontology/go-ontology/issues/30146 banded collagen fibril + fibrillar collagen cellular_component GO:0098643 - fibrillar collagen + fibrillar collagen complex fibrillar collagen @@ -20639,9 +20753,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A supramolecular complex that consists of collagen triple helices associated to form a network. + https://github.com/geneontology/go-ontology/issues/30938 + collagen network cellular_component GO:0098645 - collagen network + complex of network-forming collagens @@ -20931,6 +21047,9 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes. + Overlaps with some cellular components from GO https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 https://github.com/geneontology/go-ontology/issues/28978 @@ -22043,6 +22162,63 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + GC_ID:1 + PMID:27765632 + choanoflagellates + ncbi_taxonomy + Choanoflagellatea + Choanoflagellida + Choanomonada + Choanozoa + choanoflagellates + NCBITaxon:28009 + Choanoflagellata + + + + + choanoflagellates + + + + + + Choanoflagellatea + + + + + + Choanoflagellida + + + + + + Choanomonada + + + + + + Choanozoa + + + + + + choanoflagellates + + + + + @@ -23133,6 +23309,25 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + quality + PATO:0001591 + + curvature + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + WordNet:WordNet + + + + @@ -23539,6 +23734,29 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + + 2010-08-16T03:59:34Z + quality + compressed + PATO:0002254 + + Becoming flat but not necessarily completely flat. + flattened + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + PATOC:CVS + + + + @@ -25261,7 +25479,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -25314,14 +25532,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext ureter https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + GO @@ -25371,7 +25589,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -25418,14 +25636,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext urethra https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png - + - + Wikipedia @@ -26230,7 +26448,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -26279,14 +26497,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg https://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg - + - + FMA MA @@ -26541,15 +26759,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + - + @@ -26580,34 +26798,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext metanephros - + - + - + - + definitional - + GO - + ISBN:9780878932504 @@ -26722,8 +26940,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]. BTO:0001646 EHDAA2:0002140 @@ -26746,11 +26964,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext ureteric bud - + - + @@ -26763,13 +26981,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 - + ISBN:9780878932504 @@ -26879,7 +27097,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -26890,14 +27108,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext membrane organ membrane organ - + - + FMA-def @@ -27666,7 +27884,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -27708,14 +27926,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext gastrula stage gastrula stage - + - + BILS @@ -28126,8 +28344,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -28153,24 +28371,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext cloaca cloaca - + - + - + ZFA - + AAO @@ -28212,8 +28430,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -28231,24 +28449,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext embryonic cloaca embryonic cloaca - + - + - + EHDAA2 - + EHDAA2 @@ -28272,7 +28490,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -28304,14 +28522,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext primitive urogenital sinus http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + - + MP-def @@ -28610,15 +28828,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - - + + A fluid that is composed of blood plasma and erythrocytes. @@ -28657,34 +28875,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext blood blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -30609,7 +30827,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -30644,14 +30862,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext abdomen abdomen - + - + MA @@ -30880,7 +31098,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. AAO:0000137 BILA:0000036 @@ -30915,14 +31133,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -30962,7 +31180,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. AAO:0000139 BILA:0000038 @@ -30997,14 +31215,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -31045,7 +31263,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The middle germ layer of the embryo, between the endoderm and ectoderm. AAO:0000304 @@ -31085,14 +31303,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + - + Bgee:AN @@ -31253,7 +31471,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -31294,7 +31512,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://github.com/obophenotype/uberon/issues/685 proctodeum - + @@ -31307,7 +31525,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -31369,7 +31587,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -31434,14 +31652,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb - + - + MA @@ -32315,7 +32533,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -32366,14 +32584,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -32433,7 +32651,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. @@ -32478,7 +32696,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext central nervous system central nervous system - + @@ -32492,7 +32710,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Bgee:AN @@ -32690,7 +32908,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -32724,14 +32942,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext hindgut http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png - + - + Wikipedia @@ -33232,7 +33450,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -33257,14 +33475,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -33379,14 +33597,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -33437,24 +33655,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal pelvis https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg - + - + - + MA - + FMA @@ -33500,7 +33718,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -33535,14 +33753,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://cdn.humanatlas.io/digital-objects/ref-organ/kidney-male-right/v1.3/assets/3d-vh-m-kidney-r.glb https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg - + - + FMA @@ -33578,7 +33796,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -33622,14 +33840,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal corpuscle https://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg - + - + MA ZFA @@ -33704,7 +33922,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -33745,14 +33963,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext glomerular capsule http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg - + - + Wikipedia @@ -33842,11 +34060,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -33888,7 +34106,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext nephron tubule - + @@ -33897,14 +34115,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + GO MA ZFA @@ -33918,7 +34136,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA @@ -34142,7 +34360,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -34188,7 +34406,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://cdn.humanatlas.io/digital-objects/ref-organ/urinary-bladder-male/v1.2/assets/3d-vh-m-urinary-bladder.glb https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + @@ -34201,7 +34419,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + FMA @@ -34332,14 +34550,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]. kidney terms require review for cross-vertebrate compatibility and developmental relationships. @@ -34369,24 +34587,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext nephron http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + - + FMA - + Bgee:AN @@ -34437,14 +34655,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -34479,11 +34697,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext proximal convoluted tubule http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + @@ -34496,13 +34714,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + GO - + Wikipedia @@ -34633,7 +34851,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -34659,7 +34877,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext descending limb of loop of Henle http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + @@ -34672,7 +34890,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + FMA @@ -34696,14 +34914,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -34740,11 +34958,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext proximal straight tubule - + - + @@ -34757,13 +34975,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + MA - + MA @@ -34805,7 +35023,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -34840,7 +35058,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext distal convoluted tubule https://upload.wikimedia.org/wikipedia/commons/2/21/Kidney_nephron.png - + @@ -34853,7 +35071,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EMAPA GO MA-modified-from-isa @@ -34975,7 +35193,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The anus and surrounding regions. Encompasses both internal and external regions, where present. EFO:0000847 EHDAA2:0000122 @@ -35000,14 +35218,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext anal region http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png - + - + cjm @@ -35229,7 +35447,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -35251,14 +35469,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext kidney arcuate artery https://upload.wikimedia.org/wikipedia/commons/8/87/2610_The_Kidney.jpg - + - + MA @@ -35294,7 +35512,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + A tube extending from the mouth to the anus. @@ -35332,14 +35550,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext digestive tract digestive tract - + - + NCBIBook:NBK10107 @@ -36057,8 +36275,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -36071,7 +36289,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -36125,34 +36343,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -37025,14 +37243,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -37071,24 +37289,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext kidney - + - + - + FMA - + definitional @@ -37123,8 +37341,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -37160,11 +37378,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 pronephros - + - + @@ -37177,13 +37395,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + OG - + ZFA @@ -37584,7 +37802,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -37603,7 +37821,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]. BTO:0005157 @@ -37624,24 +37842,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext juxtaglomerular apparatus - + - + - + MA - + GO @@ -37763,8 +37981,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + The tissue comprised of mesangial cells that fill the triangular space between the macula densa and the afferent and efferent arterioles of the juxtaglomerular apparatus. EMAPA:28278 FMA:84141 @@ -37774,24 +37992,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext EDITOR_NOTE check MA part_ofs - should be spatially disjoint from renal glomerulus? extraglomerular mesangium - + - + - + MA - + MA @@ -37809,7 +38027,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -37845,14 +38063,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext coelemic cavity lumen coelemic cavity lumen - + - + definitional @@ -37948,8 +38166,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -37999,11 +38217,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -38022,13 +38240,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA - + EHDAA2 @@ -38069,7 +38287,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. mesodermal cluster @@ -38107,7 +38325,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -38120,7 +38338,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA @@ -38238,8 +38456,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]. BTO:0003940 @@ -38256,24 +38474,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext macula densa - + - + - + MA - + GO @@ -38297,16 +38515,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - + + + - + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. AAO:0010578 BTO:0001764 @@ -38339,45 +38557,45 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + BTO - + PMID:11523831 - + PMID:11523831 @@ -38816,8 +39034,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + Anatomical system that is involved in the production of hematopoietic cells. @@ -38858,24 +39076,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext hematopoietic system hematopoietic system - + - + - + FMA - + definitional @@ -39169,7 +39387,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -39188,7 +39406,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. AAO:0011086 EFO:0001982 @@ -39211,14 +39429,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext presomitic mesoderm presomitic mesoderm - + - + Bgee:AN @@ -39258,8 +39476,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. AAO:0011088 NCIT:C34279 @@ -39277,11 +39495,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] pronephric duct - + - + @@ -39294,13 +39512,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Wikipedia - + XAO @@ -39408,9 +39626,9 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - + + + @@ -39449,34 +39667,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext intermediate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + - + AAO - + EMAPA - + XAO @@ -39586,7 +39804,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. Consider adding subclasses for male and female specific variants TODO - mesonephric portion of the nephric duct @@ -39615,7 +39833,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext mesonephric duct http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + @@ -39628,7 +39846,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -39682,8 +39900,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. AAO:0011072 BTO:0001765 @@ -39712,24 +39930,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + Wikipedia - + Bgee:AN @@ -39775,7 +39993,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. AAO:0010568 EFO:0003515 @@ -39801,7 +40019,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -39814,7 +40032,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Bgee:AN @@ -39861,7 +40079,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -39900,7 +40118,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -39913,7 +40131,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 VHOG @@ -39964,15 +40182,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. AAO:0011044 @@ -39989,15 +40207,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext heart primordium heart primordium - + - + - + @@ -40010,19 +40228,19 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA - + ZFA - + XAO @@ -40051,8 +40269,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. AAO:0010571 AEO:0000212 @@ -40076,11 +40294,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -40099,13 +40317,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + VHOG:0000680 - + ZFA @@ -40344,7 +40562,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -40369,14 +40587,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] metanephric mesenchyme - + - + ISBN:9780878932504 @@ -41062,7 +41280,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults EHDAA:251 @@ -41077,14 +41295,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext intraembryonic coelom intraembryonic coelom - + - + Wikipedia @@ -41664,8 +41882,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the loop of Henle. It has a brush border epithelial morphology[GO]. TODO - ensure definition works across species. @@ -41681,24 +41899,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext proximal tubule - + - + - + GO - + GO @@ -41756,7 +41974,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The intermediate tubule is a nephron tubule that lies between the proximal and distal tubules. TODO - check for applicability across species FMA:17718 @@ -41765,14 +41983,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0004136 intermediate tubule - + - + FMA @@ -41848,8 +42066,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. XAO:0004185 first heart field @@ -41861,24 +42079,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext primary heart field primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -41931,7 +42149,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + An epithelial tube that will give rise to the mature heart. AAO:0010411 EFO:0003526 @@ -41950,14 +42168,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext heart tube heart tube - + - + ZFA-modified @@ -42176,8 +42394,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. EMAPA:27681 ZFA:0005588 @@ -42186,24 +42404,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext comma-shaped body - + - + - + cjm - + ZFA @@ -42226,8 +42444,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. TODO EMAPA:27756 @@ -42238,24 +42456,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext S-shaped body - + - + - + cjm - + GO @@ -42661,7 +42879,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -42698,14 +42916,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext glomerular capillary - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -43238,7 +43456,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -43280,14 +43498,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal afferent arteriole http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + Wikipedia @@ -43647,7 +43865,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. AAO:0011129 TAO:0001890 @@ -43661,14 +43879,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext skeletal element skeletal element - + - + VSAO @@ -43696,7 +43914,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -43729,14 +43947,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext articular system articular system - + - + FMA @@ -44032,7 +44250,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -44053,14 +44271,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext somatopleure http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png - + - + EHDAA2 @@ -44127,9 +44345,9 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - + + + @@ -44148,34 +44366,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext urogenital fold - + - + - + - + EHDAA2 - + Wikipedia - + EHDAA2 @@ -44633,21 +44851,21 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Missing definition for term UBERON:0005095. Please replace it using linked reference. class added for consistency with GO - consider merging with kidney mesenchyme. kidney anlage UBERON:0005095 kidney rudiment - + - + GO @@ -44761,7 +44979,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]. BTO:0004539 @@ -44778,14 +44996,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal connecting tubule http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + Wikipedia @@ -45509,7 +45727,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -45525,14 +45743,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext trunk mesenchyme trunk mesenchyme - + - + EHDAA2 @@ -45650,7 +45868,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. EHDAA2:0001512 EHDAA:424 @@ -45668,14 +45886,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext primitive heart tube primitive heart tube - + - + ZFA @@ -45703,7 +45921,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -45730,7 +45948,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext gonad primordium gonad primordium - + @@ -45743,7 +45961,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA @@ -45801,14 +46019,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + A mesoderm that has the potential to develop into a pronephros. AAO:0011090 EFO:0003479 @@ -45825,24 +46043,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney pronephric mesoderm - + - + - + ZFA - + Bgee:AN @@ -45889,7 +46107,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -45905,14 +46123,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext glomerular tuft - + - + Wikipedia @@ -46153,7 +46371,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -46180,14 +46398,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext glomerular basement membrane http://upload.wikimedia.org/wikipedia/commons/d/de/PhysiologieGlom%C3%A9rulaire.png - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -46271,7 +46489,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -46281,7 +46499,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext developing mesenchymal condensation developing mesenchymal condensation - + @@ -46300,7 +46518,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + AEO-modified-relation @@ -46400,7 +46618,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -46438,14 +46656,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext cloacal membrane http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png - + - + Wikipedia @@ -46479,7 +46697,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB EHDAA2:0001278 @@ -46493,7 +46711,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext notochordal plate notochordal plate - + @@ -46506,7 +46724,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -46535,7 +46753,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -46552,14 +46770,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext notochordal process notochordal process - + - + EHDAA2 @@ -47073,12 +47291,12 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + A region of nephron tubule that is part of a cortex of kidney. EMAPA:18976 MA:0002609 @@ -47087,14 +47305,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0006853 renal cortex tubule - + - + MA @@ -47770,7 +47988,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -47796,7 +48014,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext presumptive paraxial mesoderm presumptive paraxial mesoderm - + @@ -47812,7 +48030,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + https://github.com/obophenotype/uberon/issues/1277 @@ -47973,7 +48191,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -47981,7 +48199,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext dense mesenchyme tissue dense mesenchyme tissue - + @@ -47994,7 +48212,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + AEO @@ -48060,7 +48278,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -48080,14 +48298,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext layer of synovial tissue layer of synovial tissue - + - + BTO @@ -48470,7 +48688,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -48487,14 +48705,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext vascular system vascular system - + - + MA @@ -48619,7 +48837,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -48656,14 +48874,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext pelvic girdle skeleton http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray242.png - + - + PMID:21455939 @@ -48738,12 +48956,12 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + The functional tissue of the kidney, consisting of the nephrons. BTO:0003604 FMA:15574 @@ -48753,7 +48971,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0008987 renal parenchyma - + @@ -48766,7 +48984,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + FMA @@ -48837,7 +49055,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -48853,14 +49071,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext entire embryonic mesenchyme entire embryonic mesenchyme - + - + EHDAA2 @@ -48979,7 +49197,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme @@ -48987,14 +49205,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext trunk paraxial mesoderm trunk paraxial mesoderm - + - + EHDAA2 @@ -49164,7 +49382,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -49174,14 +49392,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext anterior lateral plate mesoderm anterior lateral plate mesoderm - + - + ZFA @@ -49500,7 +49718,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -49518,14 +49736,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext future cardiac atrium future cardiac atrium - + - + ZFA @@ -49669,7 +49887,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -49683,7 +49901,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext mesenchyme from somatopleure mesenchyme from somatopleure - + @@ -49696,7 +49914,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -49712,7 +49930,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -49722,14 +49940,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext microcirculatory vessel microcirculatory vessel - + - + ZFA @@ -49763,7 +49981,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -49778,7 +49996,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0010532 primitive nephron - + @@ -49791,7 +50009,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -49807,7 +50025,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -49817,7 +50035,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0010536 nephron progenitor - + @@ -49830,7 +50048,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + cjm @@ -50073,8 +50291,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. FMA:23879 SCTID:129140006 @@ -50086,11 +50304,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext subdivision of skeleton subdivision of skeleton - + - + @@ -50103,13 +50321,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + UBERONREF:0000003 - + VSAO @@ -50203,7 +50421,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -50214,7 +50432,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton postcranial axial skeletal system - + @@ -50227,7 +50445,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + cjm @@ -50264,7 +50482,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Subdivision of urinary system which consists of the kidney and the ureters. FMA:45658 @@ -50276,14 +50494,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext upper urinary tract - + - + FMA-abduced-lr @@ -50725,7 +50943,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -50739,14 +50957,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts embryonic cloacal fold - + - + EHDAA2 @@ -50769,20 +50987,20 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2:0004588 UBERON:0012361 internal anal region internal anal region - + - + EHDAA2 @@ -50792,20 +51010,20 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2:0004589 UBERON:0012469 external anal region external anal region - + - + EHDAA2 @@ -50944,7 +51162,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The precursor of the urethra. SCTID:361531004 Wikipedia:Urethral_groove @@ -50954,14 +51172,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0013241 embryonic urethral groove - + - + Wikipedia @@ -51554,7 +51772,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -51577,7 +51795,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext entire extraembryonic component entire extraembryonic component - + @@ -51590,7 +51808,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + AEO @@ -52061,7 +52279,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. NCIT:C54419 @@ -52071,14 +52289,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal pelvis/ureter - + - + NCIT @@ -52377,14 +52595,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + definitional - + @@ -52488,15 +52706,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + AAO https://github.com/geneontology/go-ontology/issues/16143 - + @@ -52777,6 +52995,40 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/src/ontology/subsets/kidney_upper_slim.tsv b/src/ontology/subsets/kidney_upper_slim.tsv index 1bd57d771..c193e7f53 100644 --- a/src/ontology/subsets/kidney_upper_slim.tsv +++ b/src/ontology/subsets/kidney_upper_slim.tsv @@ -156,7 +156,6 @@ http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation http://purl.obolibrary.org/obo/GO_0001841 neural tube formation -http://purl.obolibrary.org/obo/GO_0001977 renal system process involved in regulation of blood volume http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone http://purl.obolibrary.org/obo/GO_0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin http://purl.obolibrary.org/obo/GO_0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure @@ -389,7 +388,6 @@ http://purl.obolibrary.org/obo/GO_0070293 renal absorption http://purl.obolibrary.org/obo/GO_0070295 renal water absorption http://purl.obolibrary.org/obo/GO_0070925 organelle assembly http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region -http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis http://purl.obolibrary.org/obo/GO_0071944 cell periphery @@ -403,9 +401,9 @@ http://purl.obolibrary.org/obo/GO_0097254 renal tubular secretion http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer -http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen +http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers -http://purl.obolibrary.org/obo/GO_0098645 collagen network +http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex @@ -448,6 +446,7 @@ http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota +http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda @@ -497,6 +496,7 @@ http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0001579 contractility +http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0001873 cylindrical @@ -516,6 +516,7 @@ http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0002124 laminar http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance +http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002318 superelliptic diff --git a/subsets/blood_and_immune_upper_slim.json b/subsets/blood_and_immune_upper_slim.json index 7f4a8b93f..848199978 100644 --- a/subsets/blood_and_immune_upper_slim.json +++ b/subsets/blood_and_immune_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2025-12-17" + "val" : "2026-03-17" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2025-12-17/subsets/blood_and_immune_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2026-03-17/subsets/blood_and_immune_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -43,7 +43,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { - "val" : "FBbt:00007002" + "val" : "FBbt:00007002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:68646" }, { @@ -59,7 +65,13 @@ }, { "val" : "XAO:0003012" }, { - "val" : "ZFA:0009000" + "val" : "ZFA:0009000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -77,7 +89,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009002" + "val" : "ZFA:0009002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -93,10 +111,9 @@ "val" : "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, - "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { - "pred" : "hasExactSynonym", + "pred" : "hasNarrowSynonym", "val" : "animal stem cell" } ], "xrefs" : [ { @@ -104,7 +121,13 @@ }, { "val" : "FMA:63368" }, { - "val" : "ZFA:0005957" + "val" : "ZFA:0005957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -114,7 +137,13 @@ "val" : "Stem cells are a unique type of cell that has the remarkable ability to divide and develop into many different types of cells in the body. These cells are undifferentiated, meaning they haven't yet developed into a specific cell type, and they can renew themselves through cell division. As a result, stem cells have the potential to replace damaged or diseased cells in the body, making them a valuable tool in medicine and research.\nThere are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos and can develop into any type of cell in the body. Adult stem cells, on the other hand, are found in various tissues and organs throughout the body and can only develop into certain types of cells.\nStem cells have numerous potential applications in medicine, including the treatment of various diseases and the repair of damaged tissues. For example, they could be used to replace damaged heart tissue after a heart attack or to repair spinal cord injuries. Stem cells also have potential uses in drug development and disease research, as they can be used to model diseases and test potential therapies in vitro.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stem cell" @@ -156,7 +185,13 @@ }, { "val" : "VHOG:0001485" }, { - "val" : "ZFA:0009014" + "val" : "ZFA:0009014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -166,7 +201,13 @@ "val" : "Hematopoietic stem cells (HSCs) are multipotent cells, capable of differentiating into a wide variety of specialized blood cells. During embryonic development hematopoietic stem cells emerge from the hemogenic endothelium, a specialized subset of endothelial cells with hematopoietic potential. HSCs can be found in several organs, in particular in bone marrow, as well as peripheral blood and umbilical cord blood.\nThese stem cells have a distinctive ability to self-renew, and to differentiate into all lymphoid and myeloid cell types that together form the blood and immune systems including erythrocytes (red blood cells), leukocytes (white blood cells), and platelets. Their primary function is to ensure the continuous replenishment of the blood and immune system throughout an individual's lifespan.\nIn response to various signals, hematopoietic stem cells can either remain dormant or actively divide and differentiate. Under normal conditions, the majority of these stem cells exist in a quiescent (inactive) state, making them somewhat resistant to chemotherapy or radiation therapy in the treatment of various diseases such as leukemia. However, when the body encounters stress such as infection, bleeding, or disease, hematopoietic stem cells can rapidly become active in order to replenish the affected cells and maintain homeostasis.\nFurthermore, hematopoietic stem cells are extremely important in the field of regenerative medicine and transplantation. Regarded as lifesaving in the field of oncology, they are often extracted, purified, and reinfused back into the same (autologous transplantation) or different (allogeneic transplantation) individuals to reestablish a healthy, functioning hematopoietic and immune system after high-dose chemotherapy or to replace dysfunctional bone marrow. Understanding and manipulating the behavior of these stem cells has immense potential in treating various blood disorders, autoimmune diseases, and cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "hematopoietic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "hematopoietic stem cell" @@ -206,14 +247,26 @@ "xrefs" : [ { "val" : "BTO:0004911" }, { - "val" : "ZFA:0009015" + "val" : "ZFA:0009015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Erythroid progenitor cells play a key role in the hematopoietic system, specifically in the process of erythropoiesis – the production of red blood cells (erythrocytes). Found within the bone marrow, these cells are dedicated precursors to erythrocytes, and ensue in the hematopoietic lineage from multipotent progenitors. They represent a transitional cell type that bridges the gap between the early-stage erythroid precursors and the maturing red blood cell population.\nThe earliest committed erythroid progenitor cell is thought to be the burst-forming unit-erythroid (BFU-E) cell, which after several cell divisions gives rise to another erythroid progenitor, the colony-forming unit-erythroid (CFU-E) cell. \nErythroid progenitor cells are primarily responsible for responding to the demand for new red blood cells during conditions of physiological stress like infection, blood loss, or illness. This responsive behavior is regulated by a glycoprotein hormone known as erythropoietin, which is produced by the kidneys. Erythropoietin interacts with the receptors on the erythroid progenitor cells, prompting them to proliferate and differentiate into erythroblasts. The erythroblasts then further mature, eventually producing new, functional red cells.\nThe role of erythroid progenitor cells extends beyond their main function of erythrocyte production, as they also participate in maintaining the balance of iron in the body. Upon erythroid differentiation, they increase their uptake of transferrin-bound iron for hemoglobin synthesis, a vital component of red blood cells which allows them to transport oxygen. A deficiency or excess of erythroid progenitor cells can lead to extensive health issues such as anemia or polycythemia respectively, emphasizing their crucial role in human health.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythroid progenitor cell" @@ -249,7 +302,13 @@ }, { "val" : "FMA:83553" }, { - "val" : "ZFA:0009017" + "val" : "ZFA:0009017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -278,7 +337,13 @@ "xrefs" : [ { "val" : "FMA:84789" }, { - "val" : "ZFA:0009020" + "val" : "ZFA:0009020", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -334,7 +399,13 @@ "xrefs" : [ { "val" : "BTO:0004730" }, { - "val" : "ZFA:0009021" + "val" : "ZFA:0009021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -344,7 +415,13 @@ "val" : "The common myeloid progenitor (CMP) is a multipotent cell that serves as a crucial intermediary within the overall framework of hematopoietic cell differentiation, which is the process of blood cell production. This part of the hematopoiesis process leads to the formation of myeloid lineage cells, which includes granulocytes (neutrophils, eosinophils, and basophils), monocytes, erythrocytes (red blood cells), and megakaryocytes (platelet-forming cells). \nThe primary function of common myeloid progenitors is differentiation and proliferation into various types of mature blood cells, thereby providing a critical contribution to maintaining homeostasis within the body's immune and circulatory systems. Single-cell analyses have shown that the CMP cell population is heterogeneous with at least two distinct subpopulations, characterized by different cell surface markers and likely already committed to downstream differentiation into either the granulocyte/macrophage lineage or the megakaryocyte/erythrocyte lineage-restricted progenitor. \nThe destiny of a CMP is influenced by numerous cytokines and growth factors in its environment that promote differentiation along specific lineages. For example, IL-3 and GM-CSF stimulate the production of eosinophils, which are essential for the body’s defense against allergens and help fight fungal and parasitic infections. \nBy being able to differentiate into a wide range of different immune cells, common myeloid progenitors play a crucial role in the body's ability to respond to injuries, infections, and other physiological challenges.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "common myeloid progenitor on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "common myeloid progenitor" @@ -384,7 +461,13 @@ "val" : "megakaryocyte/erythroid progenitor cell" } ], "xrefs" : [ { - "val" : "ZFA:0009022" + "val" : "ZFA:0009022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -394,7 +477,13 @@ "val" : "The megakaryocyte-erythroid progenitor (MEP) cell belongs to the multipotent hematopoietic progenitor cells, which can give rise to multiple different cell types. They are found in the bone marrow, the primary organ where new blood cells are generated. MEPs are specially programmed to develop into two distinct blood cell lineages, namely megakaryocytes, which go on to produce platelets for blood clotting, and the erythroid lineage which consists of red blood cells responsible for oxygen transport in the body.\nThe MEP cells are the result of a decision-making process within the hematopoietic stem cell population. Hematopoietic stem cell can differentiate into multiple types of progenitor cells, including myeloid progenitor cells. A further subdivision within this myeloid lineage generates the MEP cells. Therefore, these megakaryocyte-erythroid progenitors represent a key juncture between hematopoietic stem cells and mature blood cell types in the myeloid lineage.\nMegakaryocyte-erythroid progenitor cells play a crucial role in the homeostasis of some of the most crucial constituents of blood. The megakaryocytes produced from these bipotent progenitor cells contribute to hemostasis by producing platelets - small anucleated fragments that are pivotal for blood clotting and preventing bleeding. Similarly, the erythroid lineage from MEP cells gives rise to erythrocytes, which harbor hemoglobin, the molecule that transports oxygen from lungs to every nook and corner of the body. An imbalance or malfunction in MEP function thus can significantly impact human health, leading to diseases like thrombocytopenia or anemia.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte-erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "megakaryocyte-erythroid progenitor cell" @@ -442,7 +531,13 @@ "val" : "lymphopoietic stem cell" } ], "xrefs" : [ { - "val" : "ZFA:0009023" + "val" : "ZFA:0009023", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -452,7 +547,13 @@ "val" : "The common lymphoid progenitor (CLP) arises from the multipotential hematopoietic stem cell in the bone marrow. Hematopoietic stem cells have the unique capability of developing into any type of blood cell depending on the body's requirements. In contrast, common lymphoid progenitors are already committed to the lymphoid lineage but are still oligopotent with the capability to further differentiate into various types of lymphoid cells. \nIn mice, cells in the common lymphoid progenitor population in the bone marrow can be identified by their Lin- IL7rα+ c-Kit+ Sca-1+ cell surface phenotype. The IL-7 receptor is first expressed on common lymphoid progenitor cells and distinguishes them from primitive common myeloid progenitors, and IL-7 is thought to play a critical role in the downstream development and homeostasis of immune cells.\nCLPs give rise to B lymphocytes, T lymphocytes, dendritic cells, and natural killer cells, all of which play a crucial and distinct role in immune responses. B and T lymphocytes are responsible for adaptive immunity, allowing the body to recognize and remember specific pathogens to fight them off more effectively in the future. B lymphocytes are responsible for producing antibodies, while T lymphocytes either help regulate immune responses or directly kill infected cells. Natural Killer cells are part of the body’s innate immune response, providing immediate, nonspecific defense against pathogens. They are able to interact with infected or malignant cells and induce controlled cell death, or apoptosis, effectively eliminating the threat to bodily health. Dendritic cells link the innate and adaptive immune systems by presenting antigens to T cells, promoting an adaptive response.\nThus, common lymphoid progenitors provide the basis for the body's strategic and layered defense against varied and evolving external threats, making them an essential part of the immune system.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000051" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000051", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "common lymphoid progenitor on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -474,7 +575,13 @@ }, { "val" : "MESH:D039901" }, { - "val" : "ZFA:0009024" + "val" : "ZFA:0009024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -496,13 +603,25 @@ }, { "val" : "CALOHA:TS-0650" }, { - "val" : "FBbt:00005083" + "val" : "FBbt:00005083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:70335" }, { "val" : "VHOG:0001529" }, { - "val" : "ZFA:0009025" + "val" : "ZFA:0009025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -531,7 +650,13 @@ }, { "val" : "VHOG:0001482" }, { - "val" : "ZFA:0009026" + "val" : "ZFA:0009026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -562,13 +687,25 @@ }, { "val" : "CARO:0000077" }, { - "val" : "FBbt:00000124" + "val" : "FBbt:00000124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:66768" }, { "val" : "WBbt:0003672" }, { - "val" : "ZFA:0009034" + "val" : "ZFA:0009034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -592,7 +729,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009036" + "val" : "ZFA:0009036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -602,7 +745,13 @@ "val" : "Blood vessel endothelial cells, also known as vascular endothelial cells, form the delicate inner lining of the complex circulatory system, including arteries and veins. These cells form a single, continuous monolayer inside every blood vessel, acting as a crucial biomolecular barrier between the blood, and the rest of the body tissues. They perform various fundamental biological functions, ranging from maintenance of vessel integrity to blood clotting regulation. Additionally, they control the transportation of fluids, molecules, and blood particulate matter from and into the bloodstream.\nOne of the primary functions of blood vessel endothelial cells is to maintain vascular homeostasis - a stable environment within the blood vessels. They accomplish this through several methods: they control vasomotor tone, i.e. the degree of contraction and dilation of blood vessels, by secreting vasoactive substances such as nitric oxide and endothelin; mediate responses to inflammatory stimuli; and they also regulate angiogenesis, the process of new blood vessel formations. Blood vessel endothelial cells play a significant role in preventing blood clot formation by generating a slick, non-thrombogenic surface that disallows platelets or coagulant proteins from adhering to it.\nBlood vessel endothelial cells are sensitive to various stimuli, including shear stress caused by blood flow, and they can respond by altering their morphology, function, and gene expression. This ability to adapt enables blood vessels to remodel and ensure the adequate delivery of nutrients and oxygen to all tissues, regardless of physiological demand variations. Conversely, endothelial dysfunction, often associated with a reduction in the bioavailability of endothelium-derived nitric oxide, can lead to the development of pathological conditions such as atherosclerosis, hypertension, diabetes mellitus, and even aging-related diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "blood vessel endothelial cell" @@ -613,13 +762,25 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "definition" : { + "val" : "An epithelial cell that has a flattened morphology." + }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" }, { - "val" : "ZFA:0009039" + "val" : "ZFA:0009039", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/date", + "val" : "2025-12-16T15:56:39Z" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "squamous epithelial cell" } ] @@ -642,7 +803,13 @@ "xrefs" : [ { "val" : "FMA:66773" }, { - "val" : "ZFA:0009040" + "val" : "ZFA:0009040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -652,7 +819,13 @@ "val" : "Mesothelial cells are crucial components of the mesothelium, a protective layer that lines the body's internal cavities, including pleural cavity (around the lungs), the pericardial cavity (around the heart), and the peritoneal cavity (within the abdomen). Derived from the embryonic mesoderm layer, these cells exhibit a squamous-like epithelial morphology, usually appearing as a single layer of flat, pavement-like cells in their healthy state.\nMesothelial cells play a vital role in various physiological processes, such as intraperitoneal immunity, fibrinolysis, tissue repair, and tumor suppression. Their primary function is to provide a slippery, non-adhesive and protective surface to reduce friction and eases the movements of the organs within the pleural, pericardial, and peritoneal cavities, and they participate in the transport and movement of fluid and various molecules across the so-called serosal cavities. \nThese cells have adaptive capabilities that facilitate their role in many pathological processes. In response to injury or inflammation, mesothelial cells can undergo morphological and functional changes, such as mesothelial-mesenchymal transitions, aiding in wound healing and tissue repair. Dysfunctions of mesothelial cells, however, can lead to serious health conditions, including adhesions, fibrosis, and malignancies such as peritoneal and pleural mesotheliomas.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -666,7 +839,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009043" + "val" : "ZFA:0009043", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -684,7 +863,13 @@ }, { "val" : "MESH:D001773" }, { - "val" : "ZFA:0009044" + "val" : "ZFA:0009044", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -728,7 +913,13 @@ }, { "val" : "VHOG:0001479" }, { - "val" : "ZFA:0009046" + "val" : "ZFA:0009046", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -759,14 +950,26 @@ }, { "val" : "MESH:D010010" }, { - "val" : "ZFA:0009047" + "val" : "ZFA:0009047", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Osteoclasts, derived from the monocyte/macrophage lineage, play a crucial role in bone remodeling through bone resorption. They are distinguished from other cells by their large size and their unique ability to secrete enzymes and acids that dissolve the calcium phosphate in bone. The formation of osteoclasts is influenced by two primary factors: macrophage colony-stimulating factor (M-CSF) and the ligand-activated receptor (RANKL) of nuclear factor kappa B (NF-κB).\nOsteoclasts also collaborate with osteoblasts, responsible for new bone formation, to maintain bone health and adapt bone structure. Their coordinated actions allow continuous remodeling while preserving overall bone strength and integrity. Imbalances in osteoclast activity can lead to pathological conditions. For example, excessive activity may contribute to diseases like osteoporosis, periprosthetic osteolysis, bone tumors, and Paget's disease. Other the other hand, osteoclast deficiency ca result in conditions like osteopetrosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000092" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "osteoclast on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -798,7 +1001,13 @@ }, { "val" : "FMA:62854" }, { - "val" : "ZFA:0009048" + "val" : "ZFA:0009048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -847,7 +1056,13 @@ "val" : "Mast cells, also known as mastocytes, are a type of innate immune cell. They originate from multipotent hematopoietic progenitor cells within the bone marrow, after which they migrate into nearly all tissues throughout the body. In these tissues, mast cells undergo complete maturation, with the exception of the blood. They are most densely located in the interfaces between the internal and external environments, such as the skin, respiratory system, and gastrointestinal mucosa.\nMast cells are crucial players against pathogens and serve as first-line defense components. They contain numerous granules rich in histamine and heparin and are known primarily for their role in allergy and anaphylaxis. Upon encountering an allergen, pathogen, or even certain drugs and toxins, mast cells release these mediators via degranulation. Histamine induces vasodilation and vascular permeability, allowing for immune cells to rapidly reach the site of infection, while heparin prevents clotting in these areas to facilitate immune cell recruitment. Mast cells may also selectively secrete mediators without degranulation.\nThese cells also play other functions beyond immune defense. They are involved in wound healing processes and maintenance of tissue integrity, angiogenesis, and even regulation of physiological functions in the gut. Consequently, because of their wide-ranging impacts, abnormalities in mast cell function can result in various disorders, including those related to allergies, inflammation, and autoimmune conditions.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000097" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000097", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mast cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -863,7 +1078,13 @@ "xrefs" : [ { "val" : "BTO:0001433" }, { - "val" : "ZFA:0009064" + "val" : "ZFA:0009064", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -873,7 +1094,13 @@ "val" : "Mononuclear phagocytes are immune cells that form a critical part of the body's innate immune system, the body's first line of defense against infections. Mononuclear phagocytes are characterized by the presence of a single, large nucleus. The ‘Mononuclear Phagocyte System’ nomenclature was introduced to distinguish mononuclear monocytes and macrophages from other cells with multiple nuclei. However, the cells within the mononuclear phagocyte system represent a highly heterogeneous group, all of which are able to perform highly efficient phagocytosis - engulfing and digesting microbes and cellular debris to fight infections and to maintain normal tissue homeostasis. \nIn addition to phagocytosis, mononuclear phagocytes also secrete chemical compounds to recruit other immune cells to a site of infection. These cells produce different types of signaling molecules, including cytokines, chemokines, and reactive oxygen species, triggering a cascade of responses to ensure rapid and efficient containment and neutralization of invading pathogens. These cells are also involved in antigen presentation, a process essential for stimulating an adaptive immune response. They can process and present antigens to T cells, thereby linking the innate and adaptive immune responses.\nMononuclear phagocytes play key roles in tissue repair and remodeling. After infection or injury, these cells help in the clearance of dead cells and debris, a crucial step in the initiation of tissue remodeling and the resolution of inflammation. Overall, mononuclear phagocytes are versatile cells that have tailored their functions to meet the unique challenges of different tissues within the body. They are pivotal in homeostasis, immunity, and inflammation, making them important aspects in a range of human diseases including infection, autoimmunity, and cancer.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000113" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000113", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mononuclear phagocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -898,7 +1125,13 @@ }, { "val" : "FMA:66772" }, { - "val" : "ZFA:0009065" + "val" : "ZFA:0009065", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -923,7 +1156,13 @@ "val" : "neurectoderm cell" } ], "xrefs" : [ { - "val" : "ZFA:0009080" + "val" : "ZFA:0009080", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -995,14 +1234,26 @@ }, { "val" : "FMA:70546" }, { - "val" : "ZFA:0009081" + "val" : "ZFA:0009081", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. These cells originate mainly from the mesoderm of the embryo, which forms connective tissues, muscle, and the circulatory and urinary systems. However, in adults, MSCs are found in multiple tissues, including bone marrow, adipose tissue, the umbilical cord, and dental tissues. \nThe primary function of MSCs is to maintain and repair the tissues in which they are found. When damage occurs, the MSCs are able to migrate to the site of injury, where they aid in regenerating the damaged tissue by differentiating into the required cell type and by secreting growth factors that enhance tissue repair and reduce inflammation. Furthermore, MSCs can also act as immunomodulators, suppressing immune reactions and reducing inflammation, both locally and systemically.\nApart from their role in tissue maintenance and repair, MSCs are integral to the field of regenerative medicine and are being investigated for their therapeutic potential in various clinical settings. Owing to their multipotent nature, immunomodulatory activity, and the relative ease of isolation, these cells can be engineered and translated into therapies to treat a variety of diseases, including bone and cartilage defects, liver diseases, heart disorders, and autoimmune diseases, amongst others. They have also been used as vectors for anticancer agents and in cell and gene therapy applications.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val" : "https://github.com/obophenotype/cell-ontology/issues/474" @@ -1028,14 +1279,26 @@ "val" : "APC" } ], "xrefs" : [ { - "val" : "ZFA:0009088" + "val" : "ZFA:0009088", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Professional antigen presenting cells, also known as APCs, are essential orchestrators of adaptive immunity. These cells possess the abilities to capture and process antigens and constitutively express MHC class II molecules to facilitate antigen presentation. These cells are able to deliver the three signals to activate naïve T cells, thereby initiating adaptive immunity. \nProfessional APCs include dendritic cells, macrophages, and B cells. Among these, dendritic cells are often considered the predominant APC as they have been demonstrated to activate naïve T cells. Macrophages and B cells also possess antigen-processing machinery and constitutively express MHC class II molecules. Dendritic cells and macrophages obtain antigens via phagocytosis of cells and cell debris, while B cells obtain antigens via the B cell receptor.\nAPCs are responsible for stimulating an appropriate immune response. Following antigen presentation (signal 1), they deliver costimulatory signals (signal 2) and secrete mediators such as cytokines (signal 3) that shape the subsequent immune response. APCs can also induce tolerogenic responses to self-antigens. APCs play important roles in diseases such as cancer and autoimmune diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000145" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000145", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "professional antigen presenting cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1089,7 +1352,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1104,15 +1367,30 @@ }, { "val" : "CALOHA:TS-2032" }, { - "val" : "FBbt:00005074" + "val" : "FBbt:00005074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67328" }, { "val" : "WBbt:0003675" }, { - "val" : "ZFA:0009114" + "val" : "ZFA:0009114", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle cell" }, { @@ -1131,7 +1409,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009128" + "val" : "ZFA:0009128", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1154,7 +1438,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-0995" }, { - "val" : "ZFA:0009131" + "val" : "ZFA:0009131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1168,7 +1458,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009136" + "val" : "ZFA:0009136", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1192,7 +1488,13 @@ "xrefs" : [ { "val" : "FMA:72549" }, { - "val" : "ZFA:0009137" + "val" : "ZFA:0009137", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1219,14 +1521,26 @@ "xrefs" : [ { "val" : "FMA:72554" }, { - "val" : "ZFA:0009138" + "val" : "ZFA:0009138", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesodermal cells are pluripotent and the most abundant in the human body. They contribute to the development of several structures such as the skeletal muscles, bones, heart and blood vessels, kidneys, gonads, connective tissues, and certain layers of the skin. Hence, the mesoderm is often regarded as an active and diverse layer due to its role in forming many bodily structures. \nIn embryonic development, these cells are instrumental, contributing to the body's structures through a carefully coordinated sequence of morphogenetic movements. This process forms the complex multicellular architecture of tissues and organs from a simple ball of cells. Without the function of mesodermal cells, the body's integral structures and systems would cease to form correctly, leading to developmental disorders such as axial mesodermal dysplasia complex\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesodermal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesodermal cell" @@ -1249,7 +1563,13 @@ "xrefs" : [ { "val" : "FMA:72555" }, { - "val" : "ZFA:0009139" + "val" : "ZFA:0009139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1341,7 +1661,13 @@ "val" : "Erythrocytes, also known as red blood cells, are a type of specialized cell that make up the largest percentage of cells in the human body. Erythrocytes are biconcave in shape and lack nuclei and organelles, allowing them to carry oxygen and carbon dioxide through the bloodstream more efficiently. The main function of erythrocytes is to transport oxygen from the lungs to the body's tissues and organs, and to transport carbon dioxide from the body's tissues to the lungs, where it can be exhaled out of the body. Hemoglobin, a protein located inside erythrocytes, is responsible for binding to oxygen. \nErythrocytes are produced in the bone marrow and have a lifespan of approximately 120 days before they are broken down and recycled by the body. Erythrocytes are regulated by the hormone erythropoietin, which is produced by the kidneys and liver in response to low oxygen levels in the body, thereby stimulating erythrocyte production .\nIn addition to their role in oxygen transport, erythrocytes also play a key role in regulating the body's pH levels. Without erythrocytes, oxygen would not be able to be transported efficiently throughout the body and tissues would not receive the necessary oxygen to function properly. Overall, erythrocytes are essential for maintaining the health and homeostasis of the body.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythrocyte on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythrocyte" @@ -1383,7 +1709,13 @@ "val" : "Platelets, also known as thrombocytes, are small, disc-shaped cell fragments devoid of a nucleus, yet remarkably intricate and multi-functional. They originate from the megakaryocytes in the bone marrow via a process called thrombopoiesis. Platelets are central to hemostasis, a process that prevents bleeding from broken or damaged blood vessels and facilitates wound healing. In their resting state, platelets are inactive but become quickly activated when an injury occurs.\nPlatelets function in the initiation and regulation of coagulation or clotting, which is a complex process involving several bioactive molecules. When a blood vessel is injured, the inner lining of the vessel, the endothelium, gets disrupted, exposing the underlying tissue matrix. This leads to platelet activation and adhesion to the injury site, initiating the clotting cascade. Platelets release granules packed with clotting factors, proteins, enzymes, and more platelets, which further propagates the clotting process. When activated, platelets also change their shape from discoid to a spherical form with protruding pseudopods that enables them to adhere more readily to the site of injury and mesh with one another to form a 'platelet plug'. \nAdditionally, platelets serve other physiological roles. They release growth factors enhancing tissue regeneration and wound healing. They also play a significant role in inflammation, innate immunity, and antimicrobial host defense, as they interact with leukocytes and may sequester microbes. Platelets are involved in maintaining the integrity of the blood vessels and angiogenesis, the formation of new blood vessels. Proper functioning of platelets is critical for maintaining homeostasis, while dysregulation can lead to conditions such as thrombosis or bleeding disorders.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000233" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000233", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "platelet on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1403,14 +1735,26 @@ }, { "val" : "MESH:D010586" }, { - "val" : "ZFA:0009140" + "val" : "ZFA:0009140", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Phagocytes are a heterogeneous group of white blood cells that have the capability to ingest, or ‘phagocytose’, foreign substances, pathogens, and cellular debris with high efficiency, thereby playing a vital role in the immune response. Phagocytes circulate throughout the body, patrolling and guarding against the invasion of pathogens. They are one among many types of cells that originate from hematopoietic stem cells in the bone marrow.\nUpon detection of an invading microorganism, phagocytes are mobilized by inflammatory mediators (such as bacterial proteins or complement proteins) to the infection site. They recognize surface molecules, specifically antigens, on harmful bacteria or other foreign substances with the help of opsonins, which are proteins that bind to the pathogen and make them more susceptible to phagocytosis. The process of phagocytosis involves the extension of the phagocyte's membrane around the microorganism, completely enclosing it within a microbicidal vacuole, the phagolysosome, which contains various microbicidal chemicals and digestive enzymes such as cathepsins, proteases, lysozymes, and lipases that may be employed to degrade the pathogen.\nPhagocytes are predominantly neutrophils or monocytes. Neutrophils are the most abundant type of phagocyte and are usually the first to arrive at the site of infection. Monocytes are derived from the bone marrow and can circulate to tissues and mature into local macrophages. Macrophages arrive later at sites of infection and are longer-lived than neutrophils. The process of phagocytosis must be tightly regulated to avoid host tissue damage.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000234" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000234", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "phagocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1439,7 +1783,13 @@ }, { "val" : "MESH:D008264" }, { - "val" : "ZFA:0009141" + "val" : "ZFA:0009141", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1449,7 +1799,13 @@ "val" : "Macrophages are specialized white blood cells involved in immune responses, inflammation, and tissue repair. Tissue-resident macrophages can be self-renewing and arise from embryo-derived populations. Macrophages can also originate from circulating monocytes that differentiate into macrophages upon migration into body tissues. \nMacrophages are involved in the detection, phagocytosis, and destruction of bacteria and other pathogens. They are also responsible for engulfing and removing dead cells and debris. Macrophages are also one of the cells that present pathogenic antigens to T cells so that the pathogens may be recognized and killed, or so that an antibody response may be mounted. They can also secrete cytokines, chemokines, and enzymes that further orchestrate the immune response.\nTissue-resident macrophages are diverse and heterogenous, likely as a result of the signals received from the tissue environment. The functions of these macrophages are specific to each tissue and contribute to tissue homeostasis. Dysregulation of macrophage functioning may also contribute to the development of various disease processes, such as fibrosis, chronic inflammation, or cancer.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000235" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000235", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "macrophage on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1483,7 +1839,13 @@ }, { "val" : "VHOG:0001480" }, { - "val" : "ZFA:0009142" + "val" : "ZFA:0009142", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1554,7 +1916,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009164" + "val" : "ZFA:0009164", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1574,7 +1942,13 @@ "xrefs" : [ { "val" : "FMA:86667" }, { - "val" : "ZFA:0007086" + "val" : "ZFA:0007086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1592,7 +1966,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009166" + "val" : "ZFA:0009166", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1651,7 +2031,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009190" + "val" : "ZFA:0009190", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1669,7 +2055,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009193" + "val" : "ZFA:0009193", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1702,7 +2094,13 @@ }, { "val" : "MESH:D003713" }, { - "val" : "ZFA:0009209" + "val" : "ZFA:0009209", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1712,7 +2110,13 @@ "val" : "Dendritic cells, named for their tree-like extensions called dendrites, are a type of immune cell that form a critical bridge between the innate and adaptive immune systems. They are derived from hematopoietic bone marrow progenitor cells and can be found throughout the body poised as sentinels in locations such as the skin, lungs, or liver, as well as immune organs such as the thymus, lymph nodes, or spleen. They can also be found in an immature state in the blood. Dendritic cells serve as antigen-presenting cells, with a primary function of processing and presenting antigens to T-cells to facilitate an immune response.\nUpon encountering an antigen, dendritic cells engulf the pathogen via phagocytosis and subsequently process the pathogen into antigens. These antigens are then presented on the surface of the dendritic cell in the context of major histocompatibility complex (MHC) molecules. The dendritic cell migrates to the lymph nodes, containing naive T-cells, and presents the antigens to them. This process triggers the activation of cognate T-cells into effector T-cells, which can then recognize and eradicate cells bearing the same antigen.\nAdditionally, the dendritic cells can influence the type of immune response the body will mount. They communicate with T-cells through the use of co-stimulatory molecules and cytokines. Depending on the type of co-stimulatory molecules used and the set of cytokines released, dendritic cells can promote the development of a cellular immune response, dominated by cytotoxic T cells effective against intracellular pathogens such as viruses, a humoral response, mediated by B cells and effective against extracellular bacteria and toxins, or a tolerogenic response. Thus, dendritic cells play a pivotal role in immunity, helping the body to effectively combat infections, prevent autoimmune diseases, and maintain tolerance to healthy self-tissues.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000451" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000451", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "dendritic cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1722,7 +2126,13 @@ "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009212" + "val" : "ZFA:0009212", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1747,7 +2157,13 @@ "val" : "5-Hydroxytryptamine secreting cell" } ], "xrefs" : [ { - "val" : "ZFA:0009213" + "val" : "ZFA:0009213", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1765,7 +2181,13 @@ }, { "val" : "FMA:83624" }, { - "val" : "ZFA:0009226" + "val" : "ZFA:0009226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1775,7 +2197,13 @@ "val" : "Stromal cells constitute a significant portion of the structural cellular milieu (stroma) that supports the function of parenchymal (functional) cells within an organ. The stroma is the connective, supportive framework of biological tissues with various functions depending on the specific organ and cell type. Stromal cells, derived from the mesenchymal lineage, play crucial roles in creating, maintaining, and repairing the tissue microenvironment in virtually all mammalian organs, making these cells indispensable to biological function.\nAdditionally, stromal cells secrete growth factors, cytokines, and extracellular matrix (ECM) molecules to constitute an interactive cellular network and ensure an optimal environment for the functional cells. Beyond mere structural support, these cells are instrumental in wound healing, inflammation, and maintaining tissue integrity. They may also influence the behavior of other cell types through direct cell-cell interactions or paracrine signaling.\nClinically and in research, stromal cells often draw attention due to their interaction with tumors in the cancer microenvironment. Over the past years, the role of stromal cells as facilitators of tumor growth and metastasis has been recognized increasingly. They contribute to cancer progression not only by modulating the ECM but also through the secretion of various bioactive molecules and interacting with immune cells, thereby influencing the immunologic responses to tumors.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stromal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stromal cell" @@ -1812,7 +2240,13 @@ }, { "val" : "CALOHA:TS-0683" }, { - "val" : "FBbt:00005106" + "val" : "FBbt:00005106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54527" }, { @@ -1820,7 +2254,13 @@ }, { "val" : "WBbt:0003679" }, { - "val" : "ZFA:0009248" + "val" : "ZFA:0009248", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1855,7 +2295,13 @@ }, { "val" : "VHOG:0001535" }, { - "val" : "ZFA:0009250" + "val" : "ZFA:0009250", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1918,7 +2364,13 @@ "xrefs" : [ { "val" : "FMA:83505" }, { - "val" : "ZFA:0005236" + "val" : "ZFA:0005236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1963,7 +2415,13 @@ "xrefs" : [ { "val" : "FMA:83506" }, { - "val" : "ZFA:0005241" + "val" : "ZFA:0005241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2104,7 +2562,13 @@ "val" : "A megakaryocyte is a large, unique, and complex cell type found primarily in the bone marrow, the spongy, semi-solid tissue located in the medullary cavities of certain bones. The term ‘megakaryocyte’ is derived from the Greek 'mega', meaning great, and 'karyon', referring to the nucleus. Megakaryocytes are characterized by their large size, typically with a diameter of 50-100 µm in humans, and the presence of a multilobulated nucleus; they are the largest hematopoietic cells in the bone marrow but also the rarest cells. \nThe primary function of a megakaryocyte is the production of platelets, also known as thrombocytes. Platelets are small, anucleate cell fragments that play a crucial role in the process of hemostasis, the arrest of blood loss from a damaged blood vessel. The process begins when the megakaryocyte extends long, branching processes called proplatelets, into the sinusoidal blood vessels present in the bone marrow. These proplatelets then fragment into the discoid structures recognized as platelets. Each megakaryocyte can produce thousands of platelets during its lifespan. \nApart from platelet production, megakaryocytes are involved in several other functions. They express immune-sensing receptors such as Fc-γ receptor and Toll-like receptors and produce factors such as platelet factor 4 and platelet-derived growth factor that can stimulate the immune system. Also, in certain pathological conditions, megakaryocytes release TGF-β and PDGF and contribute to bone marrow fibrosis, a condition characterized by excessive accumulation of fibrous tissue in the bone marrow leading to anemia. Recent studies have also highlighted the role of megakaryocytes in regulating hematopoiesis, the process of blood cell production. They can influence the bone marrow microenvironment and control the behavior of hematopoietic stem cells, the progenitors of all types of blood cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2148,7 +2612,13 @@ "xrefs" : [ "ISBN:0721601464", "PMCID:PMC2213186", "PMCID:PMC548021" ] } ], "xrefs" : [ { - "val" : "ZFA:0009251" + "val" : "ZFA:0009251", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2158,7 +2628,13 @@ "val" : "Granulocyte monocyte progenitor cells (GMP cells), originating from hematopoietic stem cells in the bone marrow, are a critical intermediate in myeloid cell development. Positioned at a key differentiation juncture, these cells exhibit bidirectional potential, giving rise to both granulocyte and monocyte lineages.\nTheir primary role is to generate mature granulocytes and monocytes, essential components of the body's innate immunity and inflammatory responses. Granulocytes, such as neutrophils, eosinophils, and basophils, contribute to the first line of defense against infections by migrating to the infection site and phagocytosing pathogens. Monocytes can differentiate into macrophages or dendritic cells, playing diverse roles in immune responses.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000557" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000557", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "granulocyte monocyte progenitor cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2178,7 +2654,13 @@ }, { "val" : "MESH:D012156" }, { - "val" : "ZFA:0009252" + "val" : "ZFA:0009252", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2201,7 +2683,13 @@ }, { "val" : "FMA:83551" }, { - "val" : "ZFA:0009253" + "val" : "ZFA:0009253", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2211,7 +2699,13 @@ "val" : "Promonocytes are precursor cells in the mononuclear phagocyte system, which includes the progenitors in the bone marrow, circulating monocytes and macrophages in various tissues. During monocytopoiesis, promonocytes form after monoblasts differentiate, and precede the development of monocytes and macrophages, which play an integral role in the immune system.\nPromonocytes are large, often round cells with a high nucleus to cytoplasm ratio. Their cytoplasm is laden with small azurophilic granules, and they are similar in appearance to myelocytes and metamyelocytes. \nThe maturation into monocytes is the key function of promonocytes. Once matured, they navigate their way to the bloodstream and their primary role comes into effect. Monocytes circulate in the blood for a few days before migrating to tissues to become either macrophages or dendritic cells. These cells then proceed to ingest pathogens like bacteria and viruses, helping to keep the body healthy. Thus, promonocytes play a central role in the immune system by paving the way for the development of cells that fight off toxins and attacks.\nBeyond their immune response role through differentiation, promonocytes may participate in processes such as wound healing and inflammation regulation. Defects or disruptions in promonocyte function have been linked to health disorders, including monocytic-lineage leukemias such as chronic myelomonocytic leukemia (CMML), although it is worth noting that morphologic distinction between promonocytes and other monocytic cells of various differentiation levels is difficult.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000559" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000559", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "promonocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2233,7 +2727,13 @@ "val" : "chondroplast" } ], "xrefs" : [ { - "val" : "ZFA:0009258" + "val" : "ZFA:0009258", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2258,7 +2758,13 @@ }, { "val" : "FMA:62864" }, { - "val" : "ZFA:0009265" + "val" : "ZFA:0009265", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2268,7 +2774,13 @@ "val" : "Monocytes are a type of white blood cell that constitute part of the mononuclear phagocyte system. They feature prominently in the human body's first line of defense against foreign substances as a part of the innate immune system. Monocytes are the largest of all circulating leukocytes and are identified by their bean-shaped nucleus. They are produced in the bone marrow and circulate in the bloodstream; in some conditions, they may enter tissues and differentiate into macrophages or dendritic cells or a distinct monocyte-derived cell.\nMonocytes function effectively as phagocytes, devouring harmful pathogens in the body. They engulf and destroy microbes, foreign substances, cancer cells, and other materials detrimental to the body's well-being. This process, known as phagocytosis, is vital for the body's immune response. Monocytes are also equipped to identify harmful pathogens and alert other immune cells to their presence. This is achieved by producing proinflammatory cytokines that recruit other immune cells to the affected area, amplifying the immune response.\nBeyond their role in fighting infections, monocytes play an important role in the repair and healing of tissues. After an infection or inflammation subsides, monocytes can transition into different types of cells and assist in healing by clearing dead cells and debris and facilitating tissue regeneration. They are crucial in wound healing, control of microbial growth, and tissue development.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000576" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000576", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "monocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2327,14 +2839,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009291" + "val" : "ZFA:0009291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Muscle precursor cells, commonly referred to as myogenic progenitor cells or myoblasts, play a pivotal role in the intricate processes of muscle regeneration and development. As undifferentiated cells, they harbor the potential to evolve into distinct specialized cells, specifically the muscle cell or myocyte. Their crucial contribution lies in guiding the transformation of the mesodermal layer, one of the three primary germ cell layers in the early embryo, into fully developed skeletal muscle tissues during embryonic development.\nMuscle precursor cells are characterized by their proliferative capacity and rapid differentiation into mature myocytes. They fuse into myotubes, culminating in the formation of muscle fibers. Their responsiveness to signals such as insulin-like growth factors, transforming growth factor-β, and neural inputs enables precise control over their proliferation and differentiation. This regenerative capacity equips them with the ability to repair injured or damaged muscle tissue, a critical function in preserving muscle homeostasis and overall function. These cells also actively contribute to adaptive responses, such as muscle growth and strengthening, in reaction to factors like training or aging.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "muscle precursor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle precursor cell" @@ -2355,14 +2879,26 @@ }, { "val" : "MESH:D053687" }, { - "val" : "ZFA:0009307" + "val" : "ZFA:0009307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Somatic stem cells, also known as adult stem cells, are undifferentiated cells found throughout the body post-embryonic development. They reside in specialized niches within tissues such as the bone marrow, brain, muscles, skin, and liver. Fundamentally, these cells possess the ability to self-renew, maintaining their numbers, and to generate differentiated cells that replace dying cells and repair damaged tissues. \nThe potency of somatic stem cells varies based on their tissue of origin. For instance, hematopoietic stem cells in the bone marrow exhibit multipotency, giving rise to all blood cell types. Conversely, muscle stem cells display unipotency, generating only muscle cells.\nSomatic stem cells respond to environmental signals that regulate their quiescence, activation, and differentiation states. In response to tissue injury, they proliferate and differentiate into specific mature cell types to replace lost or damaged cells. Intricate mechanisms ensure a delicate balance between self-renewal and differentiation, guiding tissue maintenance and repair without risking aberrant cell proliferation leading to tumor formation.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "somatic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somatic stem cell" @@ -2379,6 +2915,11 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", + "pred" : "hasExactSynonym", + "val" : "WBC", + "xrefs" : [ "PMID:40794848" ] + }, { "pred" : "hasExactSynonym", "val" : "leucocyte" }, { @@ -2399,7 +2940,13 @@ }, { "val" : "NCIT:C12529" }, { - "val" : "ZFA:0009309" + "val" : "ZFA:0009309", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2418,7 +2965,13 @@ "comments" : [ "Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009323" + "val" : "ZFA:0009323", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -2438,7 +2991,13 @@ }, { "val" : "MESH:D022423" }, { - "val" : "ZFA:0009324" + "val" : "ZFA:0009324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2467,7 +3026,13 @@ }, { "val" : "FMA:83516" }, { - "val" : "ZFA:0009325" + "val" : "ZFA:0009325", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2500,7 +3065,13 @@ }, { "val" : "MESH:D004900" }, { - "val" : "ZFA:0005237" + "val" : "ZFA:0005237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2518,14 +3089,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009326" + "val" : "ZFA:0009326", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Myeloid leukocytes are a group of immune cells descended from the myeloid lineage. The myeloid lineage constitutes a significant portion of the body's defense system, particularly against microbial pathogens and foreign substances. Myeloid leukocytes originate from hematopoietic stem cells located in the bone marrow. The commitment of a pluripotent hematopoietic stem cell into a myeloid progenitor cell represents the initiation step towards the development of myeloid leukocytes. Once differentiated, these cells contribute diversely to both the innate and adaptive immune responses in the body.\nMyeloid leukocytes include several distinct cell types based on functionality and structure, encompassing monocytes, macrophages, granulocytes (neutrophils, eosinophils, and basophils), and dendritic cells. Each cell type has specialized functions, occupying a unique role in the body's immune response. For instance, neutrophils are prolific phagocytes—cells that engulf and destroy pathogens—while eosinophils are instrumental in combating multicellular parasites and modulating allergic inflammatory responses. Monocytes, in addition to their phagocytic activities, can enter peripheral tissues and differentiate into macrophages or dendritic cells which are crucial for antigen presentation to T cells.\nAnother critical function of myeloid leukocytes is their involvement in tissue remodeling and repair. For example, macrophages not only play a key role in defending the body but also perform duties essential for wound healing, such as removing dead cells and stimulating tissue repair. In general, myeloid leukocytes participate in the removal of old and damaged cells, an essential process for maintaining good health and homeostasis. Through the orchestration of complex interactions and signal transductions, myeloid leukocytes provide the body with a robust defense system against foreign invaders and participate in maintaining the body's overall balance and function.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000766" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000766", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "myeloid leukocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2611,7 +3194,13 @@ "val" : "Eosinophils are a type of granulocyte derived from myeloid progenitors in the bone marrow; they are a part of the body's immune system. Named for their affinity to eosin, a red acidic dye used in staining procedures, eosinophils contribute to the immune system's response by migrating to inflammation sites, particularly those produced by allergic reactions and infections due to multicellular parasites. They comprise ~1-5% of the white blood cells in circulation.\nEosinophils play crucial roles in mediating inflammatory responses. They carry granules containing a variety of enzymes and proteins, including major basic protein (MBP), eosinophil peroxidase (EPO), eosinophil cationic protein (ECP), and eosinophil-derived neurotoxin (EDN). These enzymes and proteins are effective in killing bacteria, parasites, and some cancer cells. When exposed to an antigen, eosinophils degranulate and release these mediators to the site of infection, resulting in the destruction of invading microorganisms. Specifically, in parasitic infections, eosinophils attach themselves to the parasites and release these cytotoxic granules, causing a lethal rupture in the parasite's surface. Eosinphils may also release cytokines to attract other immune cells to sites of infection and to skew the response towards type 2 immunity.\nEosinophils are also involved in conditions such as asthma and allergic reactions. They secrete chemical mediators such as leukotrienes and prostaglandins that trigger contraction of smooth muscles, causing symptoms such as bronchoconstriction observed in asthma. However, these multifunctional cells, while useful in defending the body, may also inadvertently cause tissue damage if excessively activated. Increased numbers of eosinophils, a condition known as eosinophilia, can indicate a variety of diseases including allergies, skin disorders, parasitic and fungal infections, autoimmune diseases, certain types of cancer, and asthma.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000771" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000771", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "eosinophil on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2670,7 +3259,13 @@ }, { "val" : "MESH:D009504" }, { - "val" : "ZFA:0009327" + "val" : "ZFA:0009327", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2680,7 +3275,13 @@ "val" : "Neutrophils are an essential component of the human immune system and belong to the category of white blood cells known as granulocytes. They constitute approximately 50-70% of all white blood cells, making them the most abundant type of immune cells in mammals. Neutrophils develop in the bone marrow from hematopoietic stem cells before being released into the bloodstream where they circulate before migration into tissues, thereby exhibiting a multi-step process that includes margination, rolling, adhesion, and transmigration.\nPhenotypically and functionally, neutrophils represent a heterogeneous cell population. They are the immune system’s immediate responders and are the first cells to migrate towards the site of an infection. They play a critical role in defending the body from potential pathogenic bacteria and fungi. Their primary mechanism of action involves phagocytosis, where they engulf and destroy these microbes. Neutrophils are characterized by the presence of large quantities of granules containing antimicrobial proteins and enzymes, including defensins and myeloperoxidase, which are released once the cell has recognized and attached to the microbes. The enzymes and other antimicrobial agents can also be released into the surrounding environment, a process known as degranulation.\nNeutrophils also possess the unique biological ability to eliminate pathogens through a process called neutrophil extracellular trap (NET) formation, or NETosis. In this process, neutrophils release a mixture of DNA, histones, and granule proteins that form a web-like structure which traps and kills microbes. Notably, this process usually leads to the death of the neutrophil itself, referred to as cell suicide or programmed cell death. \nNeutrophils play a crucial role in the immune system by rapidly responding to infections and inflammation, excessive or dysregulated neutrophil activity can contribute to tissue damage and chronic inflammation, exacerbating various diseases such as rheumatoid arthritis, and neutrophils may contribute to tumor growth and progression.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000775" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000775", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "neutrophil on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2715,7 +3316,13 @@ "val" : "Myeloid dendritic cells are a subset of dendritic cells derived from the common myeloid progenitor cell. \"Conventional\" and \"myeloid\" DCs are often used interchangeably. In contrast, dendritic cells may also arise from the common lymphoid progenitor. Monocyte-derived dendritic cells may also be induced by inflammatory states.\nDendritic cells function as antigen-presenting cells and are able to activate naïve T cells to induce the adaptive immune response. Dendritic cells capture, process, and present antigens derived from pathogens to mount a specific immune response against the invading antigen. Dendritic cells also produce a range of cytokines that help in modulating and recruiting other immune cells during an immune response. \nDendritic cells can contribute to immune tolerance by deleting self-reactive T cells or by inducing regulatory T-cells, thereby preventing autoimmunity. Dendritic cells thus are important in orchestrating the adaptive immune response and are pivotal in combating infections and maintaining tolerance to self.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000782" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000782", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "myeloid dendritic cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2767,7 +3374,13 @@ "val" : "Plasmacytoid dendritic cells (pDCs), initially known as interferon-producing cells, are a unique subpopulation of dendritic cells. Unlike conventional dendritic cells (cDCs), plasmacytoid dendritic cells are characterized by their distinctive plasma cell-like morphology. These cells play vital roles in the innate and adaptive immune response, particularly in the antiviral response. Highly prevalent in the blood and lymphoid organs, pDCs are rare in non-lymphoid tissues, with the exception of inflamed tissues and tumors where they are often recruited.\nA key role of plasmacytoid dendritic cells is their rapid and robust production of type 1 interferons in response to viral infections. This is crucial for antiviral defense as interferon signals to other immune cells to increase their antiviral defenses. pDCs achieve this by detecting viral nucleic acids in the cytosol through Toll-like receptors (TLRs), specifically TLR7 and TLR9. Upon recognition, these cells quickly produce substantial amounts of interferons, which plays a significant role in the containment of viral replication and the development of acquired antiviral immunity.\nThe potential of plasmacytoid dendritic cells for antigen presentations to naive T cells is relatively low under steady-state conditions. Upon activation by certain stimuli, such as viruses or CpG oligodeoxynucleotides, they have the ability to differentiate into efficient antigen-presenting cells. This transition to activated cells involves an upregulation of major histocompatibility complex (MHC) class II molecules and co-stimulatory molecules, thus allowing them to effectively present antigenic peptides to naive T cells. This crucial function in linking innate and adaptive immunity underlines the importance of pDCs to the overall immune response.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000784" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000784", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "plasmacytoid dendritic cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2792,7 +3405,13 @@ "val" : "mature B-lymphocyte" } ], "xrefs" : [ { - "val" : "ZFA:0009331" + "val" : "ZFA:0009331", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -2832,7 +3451,13 @@ }, { "val" : "MESH:D010950" }, { - "val" : "ZFA:0009332" + "val" : "ZFA:0009332", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2860,7 +3485,13 @@ "val" : "alpha-beta T-lymphocyte" } ], "xrefs" : [ { - "val" : "ZFA:0009335" + "val" : "ZFA:0009335", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -2892,7 +3523,13 @@ "val" : "gd T cell" } ], "xrefs" : [ { - "val" : "ZFA:0009336" + "val" : "ZFA:0009336", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2902,7 +3539,13 @@ "val" : "Gamma-delta T cells, also referred to as γδ T cells, are a distinct subset of T lymphocytes that play unique roles in the immune system. They are defined by expression of heterodimeric T-cell receptors (TCRs) comprised of γ and δ chains. They share characteristics with both innate and adaptive immune cells, and unlike alpha-beta (αβ) T cells, they do not require antigen processing and Major Histocompatibility Complex (MHC) presentation for the recognition of antigens. This unique response mechanism allows them to contribute to rapid immune responses, particularly in the context of tissue injury and infection.\nDepending on the γδ TCR and the context, different subsets of gamma-delta T cells perform a variety of functions which range from regulating thermogenesis in adipose tissue to controlling the plasticity of neuronal synapses in the central nervous system. A key function is in tissue homeostasis and surveillance against infectious agents and tumors. \nThey can carry out their defense role through several mechanisms, such as cytokine production, killing of target cells, and regulation of other immune cell responses. In response to pathogens, these cells produce a wide range of cytokines, including interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), and interleukin-17 (IL-17), which help recruit and activate other immune cells to the site of infection. Furthermore, gamma-delta T cells can directly kill infected cells or cancerous cells, which is instrumental in preventing the spread of infection or malignancy.\nDespite the broadly generalized role in immunity, the function of gamma-delta T cells can vastly vary depending on their tissue location. In the skin and mucosal tissues, they provide quick response to pathogens, while in secondary lymphoid organs, their regulatory functions shape the adaptive immune response. In recent years, their role in the context of autoimmunity and cancer has gained attention, with emerging studies suggesting their potential for immunotherapeutic interventions. Thus, gamma-delta T cells serve as vital components of the immune system, providing a versatile defense mechanism against a range of pathogenic targets.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000798" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000798", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "gamma-delta T cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2931,7 +3574,13 @@ "xrefs" : [ "ISBN:781735149" ] } ], "xrefs" : [ { - "val" : "ZFA:0009343" + "val" : "ZFA:0009343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2957,7 +3606,13 @@ }, { "val" : "CALOHA:TS-0819" }, { - "val" : "ZFA:0009344" + "val" : "ZFA:0009344", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2999,7 +3654,13 @@ "val" : "T3 B cell" } ], "xrefs" : [ { - "val" : "ZFA:0009345" + "val" : "ZFA:0009345", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -3050,7 +3711,13 @@ "xrefs" : [ { "val" : "BTO:0003104" }, { - "val" : "ZFA:0009349" + "val" : "ZFA:0009349", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -3084,7 +3751,13 @@ "val" : "TN1 cell" } ], "xrefs" : [ { - "val" : "ZFA:0009350" + "val" : "ZFA:0009350", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3099,7 +3772,13 @@ "comments" : [ "Note that this is a non-mammalian cell type." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009351" + "val" : "ZFA:0009351", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3150,7 +3829,13 @@ }, { "val" : "CALOHA:TS-0448" }, { - "val" : "ZFA:0009354" + "val" : "ZFA:0009354", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -3182,7 +3867,13 @@ }, { "val" : "FMA:70338" }, { - "val" : "ZFA:0009355" + "val" : "ZFA:0009355", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3207,7 +3898,13 @@ }, { "val" : "FMA:70339" }, { - "val" : "ZFA:0009356" + "val" : "ZFA:0009356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -3241,7 +3938,13 @@ }, { "val" : "FMA:86713" }, { - "val" : "ZFA:0009357" + "val" : "ZFA:0009357", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3287,7 +3990,13 @@ "val" : "Antibody secreting cells, such as short-lived plasmablasts and long-lived plasma cells, form a key component of the adaptive immune system. These cells originate from B-lymphocytes upon exposure to antigens. They are primarily characterized by their capacity to produce and secrete large amounts of antibodies (immunoglobulins) that help to neutralize the pathogens, defining the primary role of these cells in the humoral immune response. \nAntibody secreting cells are found predominantly within the lymph nodes, spleen, and mucosa-associated lymphoid tissues. They are characterized by an extensive rough endoplasmic reticulum, reflecting the high antibody production. The interesting dynamics of these cells, switching from a nonsecreting, antigen-specific B-cell state to a high-rate immunoglobulin-secreting cell state, is a major factor in sustaining an effective adaptive immune system: Derived from a single clone, the secreted immunoglobulins have a unique antigen specificity inherited from the parent B cell. They are able to recognize specific extracellular antigens, aiding in marking harmful invaders such as viruses and bacteria for elimination, either by direct neutralization or by recruiting other immune cells for assistance.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000946" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000946", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "antibody secreting cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3385,7 +4094,13 @@ }, { "val" : "FMA:83598" }, { - "val" : "ZFA:0005830" + "val" : "ZFA:0005830", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -3433,7 +4148,13 @@ "val" : "Conventional dendritic cells (cDCs) are primarily responsible for processing antigens and presenting them to T cells to initiate an immune response. Also known as classical dendritic cells, cDCs originate from hematopoietic stem cells in the bone marrow, maturing in peripheral tissues. They are characterized by their distinct morphology, which features a central body with numerous branching extensions known as dendrites.\nThese cells have a pivotal role in adaptive immunity, bridging the gap between the innate and adaptive immune responses. They achieve this by capturing, processing, and presenting antigens to naive T-cells in the secondary lymphoid organs. This antigen presentation, in conjunction with co-stimulatory signals provided by the cDCs, instructs the T cells whether to mount an immune response against the antigen. cDCs are also very effective in the cross-presentation of antigens in the context of major histocompatibility complex (MHC) I, thereby activating CD8+ T cells an initiating a cytotoxic T cell response.\nIn addition to their role in antigen presentation, cDCs have other important functions in maintaining immune homeostasis. They can perceive signals from the surrounding tissue microenvironment, responding to inflammation, and influencing or even polarizing T cell differentiation into various effector subtypes. Importantly, while cDCs are often associated with immunogenic responses, they also play a crucial role in immune tolerance, particularly towards self-antigens, thereby preventing autoimmune reactions. In conclusion, conventional dendritic cells serve as the sentinels of the immune system, monitoring for threat signals and coordinating the appropriate immune response.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000990" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000990", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "conventional dendritic cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3554,7 +4275,13 @@ "val" : "2011-11-16T04:28:16Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0001035" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0001035", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "bone cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3810,7 +4537,13 @@ "xrefs" : [ { "val" : "FMA:69074" }, { - "val" : "ZFA:0009385" + "val" : "ZFA:0009385", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3840,7 +4573,13 @@ "xrefs" : [ { "val" : "FMA:69076" }, { - "val" : "ZFA:0009388" + "val" : "ZFA:0009388", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3937,7 +4676,13 @@ "val" : "2010-08-24T02:06:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "endothelial cell of vascular tree on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "endothelial cell of vascular tree" @@ -4070,7 +4815,13 @@ }, { "val" : "MESH:D003239" }, { - "val" : "ZFA:0009392" + "val" : "ZFA:0009392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -4100,7 +4851,13 @@ }, { "val" : "WBbt:0007028" }, { - "val" : "ZFA:0007089" + "val" : "ZFA:0007089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -4113,7 +4870,13 @@ "val" : "2010-09-15T03:39:21Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "embryonic cell (metazoa) on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "embryonic cell (metazoa)" @@ -4237,7 +5000,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007084" + "val" : "ZFA:0007084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -4286,7 +5055,13 @@ "val" : "Mesenchymal cells are a type of undifferentiated cell that possess the ability to develop into a wide variety of other cells. These cells originate from the mesoderm during embryonic development, which gives rise to tissues such as muscles, the skeletal system, and connective and vascular structures. Mesenchymal cells primarily function as progenitor cells with exceptional renewal capabilities and are characterized by their ability to migrate, aiding in tissue repair and regeneration.\nMesenchymal cells play a critical role in the development and maintenance of various biological systems throughout the body due to their versatility and adaptability. They can differentiate into more specialized cells, including osteoblasts, adipocytes, and chondrocytes, which are essential for bone, fat, and cartilage tissues, respectively. Furthermore, they contribute to the vascular and lymphatic systems through the formation of pericytes and lymphatic endothelial cells, securing the integrity of the circulatory system.\nIn the field of regenerative medicine, mesenchymal cells, particularly mesenchymal stem cells (MSCs), are of great interest due to their unique therapeutic potential. MSCs, for instance, have been implicated in wound healing and tissue repair because of their capacity to modulate the immune response. They can secrete a range of proteins and growth factors that aid in angiogenesis, the formation of new blood vessels, and the stimulation of resident progenitor cells to aid in tissue restoration.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesenchymal cell" @@ -4327,7 +5102,13 @@ "val" : "Neural crest cells are a group of transient and highly migratory cells that originate from the neuroectoderm during the early stages of embryonic development. They are multipotent cells with an exceptional degree of plasticity, capable of differentiating into various somatic cell types and therefore play a fundamental role in the formation of various organs and tissues, making them critical contributors to the developing embryo. \nAfter the initiation of neurulation (the formation of the neural tube) neural crest cells start to undergo epithelial-to-mesenchymal transition and delaminate and migrate from the dorsal neural tube to several regions throughout the embryo. They differentiate into a range of diverse cell types, such as neurons and glial cells of the peripheral nervous system, including sensory and autonomic neurons. They also contribute to the formation of adrenal glands, pigment cells in the skin (melanocytes), cardiac structures, including parts of the heart septum and major arteries, as well as bones and cartilage of the face and skull.\nDisorders or aberrations in the development or migration of the neural crest cells can lead to serious congenital malformations, such as neurocristopathies, including Hirschsprung disease, neuroblastoma, and neurofibromatosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "neural crest cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "neural crest cell" @@ -4540,7 +5321,13 @@ "val" : "Bone marrow hematopoietic cells are a category of blood-forming stem cells located within the bone marrow, the soft, spongy tissue that fills the cavities of bones. The bone marrow contains specialized environments, referred to as the stem cell niche, to nurture and regulate the development of these cells. These cells are vital for the production and development of new blood cells, functioning as the primary source of cellular regeneration throughout a person's life. They are capable of self-renewal and differentiation into every type of mature blood cell.\nHematopoietic stem cells differentiate into two main lineages: myeloid and lymphoid cells. Myeloid cells can further differentiate into red blood cells, which carry oxygen throughout the body, platelets that contribute to clot formation, and certain types of white blood cells such as neutrophils, eosinophils, basophils, and monocytes. These white blood cells play a crucial role in the innate immune response, helping to fight infection and disease. Lymphoid cells develop into other types of white blood cells: T-cells, B-cells, and innate lymphoid cells, which contribute to the cellular and humoral immune response.\nFurthermore, the bone marrow hematopoietic cells have a unique ability to replace any blood cell in the body that has been destroyed or lost due to illness or injury. Through this regenerative functionality, they are vitally important to the body's defense mechanisms, disease response, and homeostasis. These cells are used in bone marrow transplants and are of interest in regenerative medicine applications.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1001610" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1001610", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "bone marrow hematopoietic cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -4553,6 +5340,12 @@ "xrefs" : [ "GOC:TermGenie" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", + "pred" : "hasExactSynonym", + "val" : "PBMC", + "xrefs" : [ "PMID:27696124" ] + } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" @@ -4621,7 +5414,13 @@ }, { "val" : "MetaCyc:PEPTIDYLTRANSFERASE-RXN" }, { - "val" : "Reactome:R-HSA-156912" + "val" : "Reactome:R-HSA-156912", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Peptide transfer from P-site tRNA to the A-site tRNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -4629,6 +5428,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25493" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -4677,7 +5479,13 @@ "val" : "mitosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-69278" + "val" : "Reactome:R-HSA-69278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle, Mitotic" + } ] + } }, { "val" : "Wikipedia:Mitosis" } ], @@ -4956,7 +5764,13 @@ "xrefs" : [ "GOC:dph", "GOC:sdb_2009", "GOC:tb" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9823730" + "val" : "Reactome:R-HSA-9823730", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Formation of definitive endoderm" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5338,7 +6152,13 @@ "xrefs" : [ "GOC:add" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1280218" + "val" : "Reactome:R-HSA-1280218", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Adaptive Immune System" + } ] + } }, { "val" : "Wikipedia:Adaptive_immune_system" } ], @@ -6692,6 +7512,9 @@ "val" : "molecular function" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is the same as GO molecular function" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -6739,7 +7562,13 @@ "xrefs" : [ "GOC:mah" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-193672" + "val" : "Reactome:R-HSA-193672", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Sphingomyelinase is activated by the NGF:p75NTR complex" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -6810,13 +7639,37 @@ "val" : "super conserved receptor expressed in brain receptor activity" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-114552" - }, { - "val" : "Reactome:R-HSA-114558" - }, { - "val" : "Reactome:R-HSA-167408" - }, { - "val" : "Reactome:R-HSA-381706" + "val" : "Reactome:R-HSA-114552", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Thrombin-activated PARs activate G12/13" + } ] + } + }, { + "val" : "Reactome:R-HSA-114558", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Thrombin-activated PARs activate Gq" + } ] + } + }, { + "val" : "Reactome:R-HSA-167408", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "The high affinity receptor complex binds to G-protein" + } ] + } + }, { + "val" : "Reactome:R-HSA-381706", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "GLP1R:GLP1 activates G(s)" + } ] + } }, { "val" : "Wikipedia:GPCR" } ], @@ -7585,7 +8438,13 @@ "val" : "protein translation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72766" + "val" : "Reactome:R-HSA-72766", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Translation" + } ] + } }, { "val" : "Wikipedia:Translation_(genetics)" } ], @@ -7618,7 +8477,13 @@ "val" : "translation initiation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72613" + "val" : "Reactome:R-HSA-72613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Initiation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -7643,7 +8508,13 @@ "val" : "translation elongation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-156842" + "val" : "Reactome:R-HSA-156842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Elongation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -7670,7 +8541,13 @@ "val" : "translational complex disassembly" } ], "xrefs" : [ { - 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"val" : "Reactome:R-HSA-9758941" + "val" : "Reactome:R-HSA-9758941", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Gastrulation" + } ] + } }, { "val" : "Wikipedia:Gastrulation" } ], @@ -8576,7 +9579,13 @@ "val" : "pan-neural process" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9675108" + "val" : "Reactome:R-HSA-9675108", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Nervous system development" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -8640,7 +9649,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8935690" + "val" : "Reactome:R-HSA-8935690", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Digestion" + } ] + } }, { "val" : "Wikipedia:Digestion" } ], @@ -8675,7 +9690,13 @@ "val" : "blood clotting" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-109582" + "val" : "Reactome:R-HSA-109582", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Hemostasis" + } ] + } }, { "val" : "Wikipedia:Coagulation" } ], @@ -8786,7 +9807,13 @@ "val" : "metabolism" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1430728" + "val" : "Reactome:R-HSA-1430728", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism" + } ] + } }, { "val" : "Wikipedia:Metabolism" } ], @@ -9253,7 +10280,13 @@ "val" : "embryonal development" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-5619507" + "val" : "Reactome:R-HSA-5619507", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of HOX genes during differentiation" + } ] + } }, { "val" : "Wikipedia:Embryogenesis" } ], @@ -9493,7 +10526,13 @@ "val" : "caspase-independent apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-5357801" + "val" : "Reactome:R-HSA-5357801", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Programmed Cell Death" + } ] + } }, { "val" : "Wikipedia:Programmed_cell_death" } ], @@ -9565,7 +10604,13 @@ "xrefs" : [ "GOC:ai" ] }, "xrefs" : [ { - "val" : "Reactome:R-HSA-8981607" + "val" : "Reactome:R-HSA-8981607", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Intracellular oxygen transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -9743,7 +10788,13 @@ "val" : "RNA metabolism" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953854" + "val" : "Reactome:R-HSA-8953854", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of RNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -9909,17 +10960,42 @@ "xrefs" : [ { "val" : "EC:2.-.-.-" }, { - "val" : "Reactome:R-HSA-1483089" - }, { - "val" : "Reactome:R-HSA-1483186" - }, { - "val" : "Reactome:R-HSA-5333607" - }, { - "val" : "Reactome:R-HSA-5668414" - }, { - "val" : "Reactome:R-HSA-8868783" + "val" : "Reactome:R-HSA-1483089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "PE is converted to PS by PTDSS2" + } ] + } + }, { + "val" : "Reactome:R-HSA-1483186", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "PC is converted to PS by PTDSS1" + } ] + } + }, { + "val" : "Reactome:R-HSA-5668414", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" + } ] + } + }, { + "val" : "Reactome:R-HSA-8868783", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -9941,17 +11017,44 @@ "xrefs" : [ { "val" : "EC:2.3.-.-" }, { - "val" : "Reactome:R-HSA-159431" - }, { - "val" : "Reactome:R-HSA-192312" - }, { - "val" : "Reactome:R-HSA-193491" - }, { - "val" : "Reactome:R-HSA-8858298" + "val" : "Reactome:R-HSA-159431", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine" + } ] + } + }, { + "val" : "Reactome:R-HSA-192312", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate" + } ] + } + }, { + "val" : "Reactome:R-HSA-193491", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate" + } ] + } + }, { + "val" : "Reactome:R-HSA-8858298", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "HRASLS transfer acyl group from PC to PE to form NAPE" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/20486" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -9974,6 +11077,9 @@ "val" : "EC:2.3.2.-" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -10058,7 +11164,13 @@ "val" : "multicellular organismal protein metabolic process" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-392499" + "val" : "Reactome:R-HSA-392499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of proteins" + } ] + } }, { "val" : "Wikipedia:Protein_metabolism" } ], @@ -10438,7 +11550,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -10452,6 +11564,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/26279" }, { @@ -10468,6 +11583,7 @@ "val" : "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:18391171" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "formation of a cell surface projection" @@ -10477,6 +11593,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -11093,7 +12212,13 @@ "val" : "granulocyte cell differentiation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9616222" + "val" : "Reactome:R-HSA-9616222", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transcriptional regulation of granulopoiesis" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -11612,6 +12737,9 @@ "val" : "protein-protein complex" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is not covalently bonded, which conflicts with changes to the parent definition." + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -11762,7 +12890,13 @@ "val" : "ATP hydrolysis coupled ion transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-983712" + "val" : "Reactome:R-HSA-983712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ion channel transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -12307,8 +13441,8 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "Any biological process involved in the maintenance of an internal steady state.", - "xrefs" : [ "GOC:jl", "ISBN:0395825172" ] + "val" : "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions.", + "xrefs" : [ "PMID:26265027" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_mouse" ], "synonyms" : [ { @@ -12331,6 +13465,9 @@ "val" : "regulation of homeostatic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/31175" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -12483,7 +13620,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -12495,6 +13632,9 @@ "val" : "cellular projection" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" }, { @@ -12982,7 +14122,13 @@ "val" : "interspecies interaction with other organisms" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9824443" + "val" : "Reactome:R-HSA-9824443", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Parasitic Infection Pathways" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -13092,7 +14238,13 @@ "val" : "nonspecific immune response" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-168249" + "val" : "Reactome:R-HSA-168249", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Innate Immune System" + } ] + } }, { "val" : "Wikipedia:Innate_immune_system" } ], @@ -13957,7 +15109,13 @@ "xrefs" : [ "GOC:ai" ] }, "xrefs" : [ { - "val" : "Reactome:R-HSA-198933" + "val" : "Reactome:R-HSA-198933", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -14237,7 +15395,13 @@ "val" : "leukocyte trafficking" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-202733" + "val" : "Reactome:R-HSA-202733", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell surface interactions at the vascular wall" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -14550,7 +15714,13 @@ "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953897" + "val" : "Reactome:R-HSA-8953897", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cellular responses to stimuli" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -14576,11 +15746,29 @@ "val" : "ATP hydrolysis coupled transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382556" + "val" : "Reactome:R-HSA-382556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ABC-family proteins mediated transport" + } ] + } }, { - "val" : "Reactome:R-HSA-425407" + "val" : "Reactome:R-HSA-425407", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "SLC-mediated transmembrane transport" + } ] + } }, { - "val" : "Reactome:R-HSA-5223345" + "val" : "Reactome:R-HSA-5223345", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Miscellaneous transport and binding events" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", @@ -14660,7 +15848,13 @@ "xrefs" : [ "GOC:dph" ] }, "xrefs" : [ { - "val" : "Reactome:R-HSA-9664424" + "val" : "Reactome:R-HSA-9664424", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell recruitment (pro-inflammatory response)" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -14745,7 +15939,13 @@ "val" : "single-organism membrane organization" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-199991" + "val" : "Reactome:R-HSA-199991", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Membrane Trafficking" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", @@ -15379,11 +16579,29 @@ "val" : "induction of apoptosis by extracellular signals" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-193681" + "val" : "Reactome:R-HSA-193681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ceramide signalling" + } ] + } }, { - "val" : "Reactome:R-HSA-204998" + "val" : "Reactome:R-HSA-204998", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell death signalling via NRAGE, NRIF and NADE" + } ] + } }, { - "val" : "Reactome:R-HSA-75157" + "val" : "Reactome:R-HSA-75157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "FasL/ CD95L signaling" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -15413,7 +16631,13 @@ "val" : "apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-75153" + "val" : "Reactome:R-HSA-75153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptotic execution phase" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -15555,7 +16779,7 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098643", - "lbl" : "fibrillar collagen", + "lbl" : "fibrillar collagen complex", "type" : "CLASS", "meta" : { "definition" : { @@ -15565,6 +16789,9 @@ "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "banded collagen fibril" + }, { + "pred" : "hasExactSynonym", + "val" : "fibrillar collagen" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -15608,14 +16835,21 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098645", - "lbl" : "collagen network", + "lbl" : "complex of network-forming collagens", "type" : "CLASS", "meta" : { "definition" : { "val" : "A supramolecular complex that consists of collagen triple helices associated to form a network.", "xrefs" : [ "GOC:dos", "PMID:21421911" ] }, + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "collagen network" + } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30938" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -15814,8 +17048,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.", - "xrefs" : [ "GOC:kmv" ] + "val" : "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { @@ -15823,6 +17056,12 @@ "val" : "cellular anatomical entity" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Overlaps with some cellular components from GO" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" }, { @@ -16561,7 +17800,13 @@ "xrefs" : [ "GOC:obol" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-6785631" + "val" : "Reactome:R-HSA-6785631", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ERBB2 Regulates Cell Motility" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -17005,6 +18250,46 @@ "val" : "Eukaryota" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "lbl" : "Choanoflagellata", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "choanoflagellates" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellatea" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellida" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanomonada" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanozoa" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "choanoflagellates" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + }, { + "val" : "PMID:27765632" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "lbl" : "Euarchontoglires", @@ -18106,6 +19391,21 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0001591", + "lbl" : "curvature", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.", + "xrefs" : [ "WordNet:WordNet" ] + }, + "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0001690", "lbl" : "contractile", @@ -18438,6 +19738,32 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0002254", + "lbl" : "flattened", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane.", + "xrefs" : [ "PATOC:CVS" ] + }, + "comments" : [ "Becoming flat but not necessarily completely flat." ], + "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], + "synonyms" : [ { + "pred" : "hasRelatedSynonym", + "val" : "compressed" + } ], + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0002-2061-091X" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2010-08-16T03:59:34Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002266", "lbl" : "3-D shape", @@ -22148,7 +23474,13 @@ }, { "val" : "TAO:0005425" }, { - "val" : "UMLS:C0036760" + "val" : "UMLS:C0036760", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Serosa" + } ] + } }, { "val" : "Wikipedia:Serous_membrane" }, { @@ -22214,7 +23546,13 @@ "xrefs" : [ { "val" : "AAO:0011123" }, { - "val" : "FBbt:00100314" + "val" : "FBbt:00100314", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:30320" }, { @@ -22224,7 +23562,13 @@ }, { "val" : "TAO:0005171" }, { - "val" : "UMLS:C0687028" + "val" : "UMLS:C0687028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Duct" + } ] + } }, { "val" : "Wikipedia:Duct_(anatomy)" }, { @@ -22304,7 +23648,13 @@ }, { "val" : "FAO:0000001" }, { - "val" : "FBbt:00007001" + "val" : "FBbt:00007001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:305751" }, { @@ -22389,7 +23739,13 @@ }, { "val" : "SCTID:272625005" }, { - "val" : "UMLS:C0178784" + "val" : "UMLS:C0178784", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ" + } ] + } }, { "val" : "WBbt:0003760" }, { @@ -22397,7 +23753,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33090" @@ -22517,47 +23879,161 @@ }, { "val" : "BilaDO:0000004" }, { - "val" : "BtauDv:0000078" - }, { - "val" : "CfamDv:0000007" - }, { - "val" : "ChirDv:0000014" - }, { - "val" : "DpseDv:0000005" - }, { - "val" : "DsimDv:0000005" + "val" : "BtauDv:0000078", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001272" }, { - "val" : "EcabDv:0000007" + "val" : "EcabDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005369" }, { - "val" : "FcatDv:0000007" - }, { - "val" : "GgalDv:0000076" - }, { - "val" : "GgorDv:0000032" - }, { - "val" : "HsapDv:0010000" - }, { - "val" : "MmulDv:0000052" - }, { - "val" : "MmusDv:0000092" - }, { - "val" : "OanaDv:0000007" - }, { - "val" : "OariDv:0000024" - }, { - "val" : "PpanDv:0000041" - }, { - "val" : "PtroDv:0000052" - }, { - "val" : "RnorDv:0000061" - }, { - "val" : "SsalDv:0000040" - }, { - "val" : "SscrDv:0000084" + "val" : "FcatDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000076", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000032", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0010000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000041", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000061", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000041" }, { @@ -22588,65 +24064,203 @@ "val" : "embryogenesis" } ], "xrefs" : [ { - "val" : "AcarDv:0000002" + "val" : "AcarDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BilaDO:0000002" }, { - "val" : "BtauDv:0000002" - }, { - "val" : "CfamDv:0000002" - }, { - "val" : "ChirDv:0000002" - }, { - "val" : "CporDv:0000002" - }, { - "val" : "DpseDv:0000002" - }, { - "val" : "DsimDv:0000002" + "val" : "BtauDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EV:0300001" }, { - 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"val" : "SsalDv:0000002" - }, { - "val" : "SscrDv:0000002" + "val" : "SsalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000003" }, { @@ -22719,7 +24333,13 @@ }, { "val" : "SCTID:118966000" }, { - "val" : "UMLS:C1519343" + "val" : "UMLS:C1519343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System_Part" + } ] + } }, { "val" : "galen:ComplexSkeletalStructure" } ], @@ -22756,7 +24376,13 @@ }, { "val" : "OGES:000024" }, { - "val" : "SsalDv:0000038" + "val" : "SsalDv:0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000022" }, { @@ -22826,55 +24452,193 @@ "val" : "lifespan" } ], "xrefs" : [ { - 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"val" : "MdomDv:0000000" - }, { - "val" : "MmulDv:0000000" - }, { - "val" : "MmusDv:0000000" - }, { - "val" : "OanaDv:0000000" - }, { - "val" : "OariDv:0000000" - }, { - "val" : "OcunDv:0000000" + "val" : "MdomDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000090" }, { - "val" : "PpanDv:0000000" - }, { - "val" : "PtroDv:0000000" - }, { - "val" : "RnorDv:0000000" - }, { - "val" : "SsalDv:0000000" - }, { - "val" : "SscrDv:0000000" + "val" : "PpanDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000002" }, { @@ -23040,7 +24942,13 @@ }, { "val" : "BilaDO:0000005" }, { - "val" : "ChirDv:0000003" + "val" : "ChirDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001322" }, { @@ -23048,21 +24956,57 @@ }, { "val" : "FBdv:00005288" }, { - "val" : "HsapDv:0000003" - }, { - "val" : "MmusDv:0000003" + "val" : "HsapDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "NCIT:C12601" }, { - "val" : "OariDv:0000009" + "val" : "OariDv:0000009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000100" }, { - "val" : "RnorDv:0000048" - }, { - "val" : "SsalDv:0000003" - }, { - "val" : "SscrDv:0000087" + "val" : "RnorDv:0000048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "VHOG:0000745" }, { @@ -23095,33 +25039,81 @@ }, { "val" : "BilaDO:0000006" }, { - "val" : "ChirDv:0000004" + "val" : "ChirDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001290" }, { "val" : "FBdv:00000054" }, { - "val" : "GgalDv:0000064" - }, { - "val" : "HsapDv:0000005" + "val" : "GgalDv:0000064", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D002970" }, { - "val" : "MmusDv:0000004" + "val" : "MmusDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000015" }, { "val" : "OGES:000020" }, { - "val" : "OariDv:0000010" + "val" : "OariDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000200" }, { - "val" : "RnorDv:0000049" - }, { - "val" : "SsalDv:0000004" - }, { - "val" : "SscrDv:0000088" + "val" : "RnorDv:0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000088", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Cleavage_(embryo)" }, { @@ -23149,15 +25141,39 @@ }, { "val" : "BilaDO:0000007" }, { - "val" : "ChirDv:0000010" + "val" : "ChirDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001282" }, { - "val" : "GgalDv:0000091" - }, { - "val" : "HsapDv:0000006" - }, { - "val" : "MmusDv:0000007" + "val" : "GgalDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000003" }, { @@ -23165,13 +25181,37 @@ }, { "val" : "OGES:000021" }, { - "val" : "OariDv:0000025" - }, { - "val" : "RnorDv:0000054" - }, { - "val" : "SsalDv:0000012" - }, { - "val" : "SscrDv:0000089" + "val" : "OariDv:0000025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000005" }, { @@ -23232,29 +25272,77 @@ }, { "val" : "BilaDO:0000008" }, { - "val" : "ChirDv:0000011" + "val" : "ChirDv:0000011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001296" }, { "val" : "FBdv:00005317" }, { - "val" : "GgalDv:0000092" - }, { - "val" : "HsapDv:0000010" - }, { - "val" : "MmusDv:0000013" + "val" : "GgalDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000004" }, { "val" : "OGES:000019" }, { - "val" : "OariDv:0000026" - }, { - "val" : "RnorDv:0000005" - }, { - "val" : "SsalDv:0000016" - }, { - "val" : "SscrDv:0000090" + "val" : "OariDv:0000026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000010" }, { @@ -23281,19 +25369,61 @@ }, { "val" : "BilaDO:0000009" }, { - "val" : "ChirDv:0000012" - }, { - "val" : "GgalDv:0000093" - }, { - "val" : "HsapDv:0000012" - }, { - "val" : "MmusDv:0000017" - }, { - "val" : "OariDv:0000027" - }, { - "val" : "RnorDv:0000007" - }, { - "val" : "SscrDv:0000091" + "val" : "ChirDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "XAO:1000006" } ], @@ -23326,25 +25456,73 @@ }, { "val" : "BilaDO:0000010" }, { - "val" : "ChirDv:0000013" - }, { - "val" : "GgalDv:0000094" - }, { - "val" : "HsapDv:0000015" - }, { - "val" : "MmusDv:0000018" + "val" : "ChirDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000018", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000005" }, { "val" : "OGES:000032" }, { - "val" : "OariDv:0000028" - }, { - "val" : "RnorDv:0000055" - }, { - "val" : "SsalDv:0000022" - }, { - "val" : "SscrDv:0000086" + "val" : "OariDv:0000028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Organogenesis" } ], @@ -23443,7 +25621,13 @@ }, { "val" : "EMAPA:16262" }, { - "val" : "FBbt:00003126" + "val" : "FBbt:00003126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:49184" }, { @@ -23559,7 +25743,13 @@ }, { "val" : "TAO:0000007" }, { - "val" : "UMLS:C0005767" + "val" : "UMLS:C0005767", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood" + } ] + } }, { "val" : "VHOG:0000224" }, { @@ -23749,7 +25939,13 @@ "xrefs" : [ { "val" : "BTO:0001837" }, { - "val" : "EMAPA:37950" + "val" : "EMAPA:37950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:62889" }, { @@ -23818,7 +26014,13 @@ }, { "val" : "NCIT:C34062" }, { - "val" : "UMLS:C1516992" + "val" : "UMLS:C1516992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland_Fluid_or_Secretion" + } ] + } }, { "val" : "galen:Secretion" } ], @@ -23873,7 +26075,13 @@ }, { "val" : "EMAPA:35178" }, { - "val" : "FBbt:00007019" + "val" : "FBbt:00007019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9669" }, { @@ -23947,7 +26155,13 @@ }, { "val" : "EHDAA2:0003005" }, { - "val" : "FBbt:00007017" + "val" : "FBbt:00007017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:5897" }, { @@ -23959,7 +26173,13 @@ }, { "val" : "TGMA:0001825" }, { - "val" : "UMLS:C0524461" + "val" : "UMLS:C0524461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lumen_Space" + } ] + } }, { "val" : "VHOG:0001728" }, { @@ -24002,7 +26222,13 @@ }, { "val" : "EHDAA2:0003006" }, { - "val" : "FBbt:00007016" + "val" : "FBbt:00007016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67165" }, { @@ -24054,7 +26280,13 @@ }, { "val" : "EHDAA2:0003007" }, { - "val" : "FBbt:00007015" + "val" : "FBbt:00007015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67112" }, { @@ -24134,7 +26366,13 @@ }, { "val" : "EV:0100000" }, { - "val" : "FBbt:00004856" + "val" : "FBbt:00004856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7149" }, { @@ -24150,7 +26388,13 @@ }, { "val" : "TGMA:0001831" }, { - "val" : "UMLS:C0460002" + "val" : "UMLS:C0460002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_System" + } ] + } }, { "val" : "VHOG:0001725" }, { @@ -24248,7 +26492,13 @@ }, { "val" : "EV:0100016" }, { - "val" : "FBbt:00000001" + "val" : "FBbt:00000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:256135" }, { @@ -24340,7 +26590,13 @@ }, { "val" : "EMAPA:36031" }, { - "val" : "FBbt:00007009" + "val" : "FBbt:00007009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7153" }, { @@ -24360,7 +26616,13 @@ }, { "val" : "TGMA:0001840" }, { - "val" : "UMLS:C0229962" + "val" : "UMLS:C0229962", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Body_Part" + } ] + } }, { "val" : "VHOG:0001758" }, { @@ -24416,7 +26678,13 @@ }, { "val" : "EHDAA2:0003040" }, { - "val" : "FBbt:00007013" + "val" : "FBbt:00007013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:63863" }, { @@ -24455,7 +26723,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007277" + "val" : "FBbt:00007277", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "VHOG:0001737" } ], @@ -24514,7 +26788,13 @@ }, { "val" : "EMAPA:35868" }, { - "val" : "FBbt:00007003" + "val" : "FBbt:00007003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9637" }, { @@ -24530,7 +26810,13 @@ }, { "val" : "TGMA:0001844" }, { - "val" : "UMLS:C0040300" + "val" : "UMLS:C0040300", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Tissue" + } ] + } }, { "val" : "VHOG:0001757" }, { @@ -24586,7 +26872,13 @@ }, { "val" : "EHDAA2:0003055" }, { - "val" : "FBbt:00007010" + "val" : "FBbt:00007010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000055" }, { @@ -24652,7 +26944,13 @@ }, { "val" : "EMAPA:32738" }, { - "val" : "FBbt:00007005" + "val" : "FBbt:00007005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9639" }, { @@ -24670,7 +26968,13 @@ }, { "val" : "TAO:0001486" }, { - "val" : "UMLS:C0014609" + "val" : "UMLS:C0014609", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Epithelium" + } ] + } }, { "val" : "VHOG:0000387" }, { @@ -24729,7 +27033,13 @@ }, { "val" : "TAO:0001494" }, { - "val" : "UMLS:C0682575" + "val" : "UMLS:C0682575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stratified_Epithelium" + } ] + } }, { "val" : "Wikipedia:Stratified_epithelium" }, { @@ -24782,7 +27092,13 @@ }, { "val" : "TAO:0001498" }, { - "val" : "UMLS:C0836133" + "val" : "UMLS:C0836133", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_squamous_epithelium" }, { @@ -24841,7 +27157,13 @@ }, { "val" : "TAO:0001495" }, { - "val" : "UMLS:C0682574" + "val" : "UMLS:C0682574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Epithelium" + } ] + } }, { "val" : "XAO:0004007" }, { @@ -24941,7 +27263,13 @@ }, { "val" : "EMAPA:16039" }, { - "val" : "FBbt:00000052" + "val" : "FBbt:00000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69068" }, { @@ -24959,7 +27287,13 @@ }, { "val" : "SCTID:57991002" }, { - "val" : "UMLS:C0013935" + "val" : "UMLS:C0013935", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryo" + } ] + } }, { "val" : "VHOG:0001766" }, { @@ -25021,7 +27355,13 @@ }, { "val" : "EMAPA:36033" }, { - "val" : "FBbt:00000110" + "val" : "FBbt:00000110", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69069" }, { @@ -25035,9 +27375,21 @@ }, { "val" : "TAO:0001122" }, { - "val" : "UMLS:C0920502" - }, { - "val" : "UMLS:C1708239" + "val" : "UMLS:C0920502", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Tissue" + } ] + } + }, { + "val" : "UMLS:C1708239", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Germinal_Layer" + } ] + } }, { "val" : "VHOG:0001223" }, { @@ -25084,7 +27436,13 @@ }, { "val" : "EV:0100003" }, { - "val" : "FBbt:00000111" + "val" : "FBbt:00000111", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69070" }, { @@ -25104,7 +27462,13 @@ }, { "val" : "TAO:0000016" }, { - "val" : "UMLS:C0013574" + "val" : "UMLS:C0013574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ectoderm" + } ] + } }, { "val" : "VHOG:0000153" }, { @@ -25155,7 +27519,13 @@ }, { "val" : "EV:0100005" }, { - "val" : "FBbt:00000125" + "val" : "FBbt:00000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69071" }, { @@ -25173,7 +27543,13 @@ }, { "val" : "TAO:0000017" }, { - "val" : "UMLS:C0014144" + "val" : "UMLS:C0014144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endoderm" + } ] + } }, { "val" : "VHOG:0000154" }, { @@ -25239,7 +27615,13 @@ }, { "val" : "EV:0100006" }, { - "val" : "FBbt:00000126" + "val" : "FBbt:00000126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69072" }, { @@ -25257,7 +27639,13 @@ }, { "val" : "TAO:0000041" }, { - "val" : "UMLS:C0025485" + "val" : "UMLS:C0025485", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesoderm" + } ] + } }, { "val" : "VHOG:0000152" }, { @@ -25327,7 +27715,13 @@ }, { "val" : "EMAPA:16263" }, { - "val" : "FBbt:00000439" + "val" : "FBbt:00000439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:295846" }, { @@ -25337,7 +27731,13 @@ }, { "val" : "TGMA:0000135" }, { - "val" : "UMLS:C1514977" + "val" : "UMLS:C1514977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stomodeum" + } ] + } }, { "val" : "Wikipedia:Stomodeum" }, { @@ -25420,7 +27820,13 @@ }, { "val" : "TAO:0000114" }, { - "val" : "UMLS:C0018787" + "val" : "UMLS:C0018787", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Heart" + } ] + } }, { "val" : "VHOG:0000276" }, { @@ -25511,7 +27917,13 @@ }, { "val" : "TAO:0000367" }, { - "val" : "UMLS:C0022417" + "val" : "UMLS:C0022417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint" + } ] + } }, { "val" : "VHOG:0001276" }, { @@ -25564,7 +27976,13 @@ }, { "val" : "EFO:0000793" }, { - "val" : "FBbt:00005055" + "val" : "FBbt:00005055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7152" }, { @@ -25625,7 +28043,13 @@ }, { "val" : "CALOHA:TS-2103" }, { - "val" : "MESH:D002319" + "val" : "MESH:D002319", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "VHOG:0001248" }, { @@ -25633,7 +28057,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6073" @@ -25705,7 +28135,13 @@ }, { "val" : "TAO:0000548" }, { - "val" : "UMLS:C0026845" + "val" : "UMLS:C0026845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle" + } ] + } }, { "val" : "VSAO:0005038" }, { @@ -25768,7 +28204,13 @@ }, { "val" : "EV:0100162" }, { - "val" : "FBbt:00005093" + "val" : "FBbt:00005093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7157" }, { @@ -25788,7 +28230,13 @@ }, { "val" : "TAO:0000396" }, { - "val" : "UMLS:C0027763" + "val" : "UMLS:C0027763", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System" + } ] + } }, { "val" : "VHOG:0000402" }, { @@ -25872,7 +28320,13 @@ }, { "val" : "EV:0100163" }, { - "val" : "FBbt:00005094" + "val" : "FBbt:00005094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:55675" }, { @@ -25890,7 +28344,16 @@ }, { "val" : "TAO:0000012" }, { - "val" : "UMLS:C0927232" + "val" : "UMLS:C0927232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1099" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Central_Nervous_System" + } ] + } }, { "val" : "VHOG:0000293" }, { @@ -25904,7 +28367,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -25951,7 +28420,13 @@ }, { "val" : "EHDAA2:0003171" }, { - "val" : "FBbt:00005495" + "val" : "FBbt:00005495", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86589" }, { @@ -25959,7 +28434,13 @@ }, { "val" : "NCIT:C34275" }, { - "val" : "UMLS:C0678727" + "val" : "UMLS:C0678727", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium" + } ] + } }, { "val" : "Wikipedia:Primordium" }, { @@ -26023,7 +28504,13 @@ }, { "val" : "TAO:0001135" }, { - "val" : "UMLS:C0231024" + "val" : "UMLS:C0231024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Tube" + } ] + } }, { "val" : "VHOG:0000307" }, { @@ -26068,7 +28555,13 @@ }, { "val" : "EHDAA2:0002229" }, { - "val" : "FBbt:10000000" + "val" : "FBbt:10000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:62955" }, { @@ -26082,7 +28575,13 @@ }, { "val" : "TGMA:0001822" }, { - "val" : "UMLS:C1515976" + "val" : "UMLS:C1515976", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Structure_System_or_Substance" + } ] + } }, { "val" : "WBbt:0000100" }, { @@ -26138,7 +28637,13 @@ }, { "val" : "TAO:0005154" }, { - "val" : "UMLS:C0039097" + "val" : "UMLS:C0039097", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Synovial_Fluid" + } ] + } }, { "val" : "Wikipedia:Synovial_fluid" }, { @@ -26192,7 +28697,13 @@ }, { "val" : "SCTID:361918002" }, { - "val" : "UMLS:C0086610" + "val" : "UMLS:C0086610", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesothelium" + } ] + } }, { "val" : "Wikipedia:Mesothelium" } ], @@ -26247,7 +28758,13 @@ }, { "val" : "TAO:0000434" }, { - "val" : "UMLS:C0037253" + "val" : "UMLS:C0037253", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System" + } ] + } }, { "val" : "VHOG:0001254" }, { @@ -26329,7 +28846,13 @@ }, { "val" : "TAO:0001514" }, { - "val" : "UMLS:C0262950" + "val" : "UMLS:C0262950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bone" + } ] + } }, { "val" : "VHOG:0001190" }, { @@ -26379,7 +28902,13 @@ "xrefs" : [ "Wikipedia:Articular_capsule" ] } ], "xrefs" : [ { - "val" : "EMAPA:37621" + "val" : "EMAPA:37621", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:34836" }, { @@ -26395,7 +28924,13 @@ }, { "val" : "SCTID:182238002" }, { - "val" : "UMLS:C0206207" + "val" : "UMLS:C0206207", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint_Capsule" + } ] + } }, { "val" : "Wikipedia:Articular_capsule" }, { @@ -26461,13 +28996,25 @@ }, { "val" : "EMAPA:16247" }, { - "val" : "FBbt:00003125" + "val" : "FBbt:00003125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45615" }, { "val" : "MA:0000917" }, { - "val" : "MESH:D041981" + "val" : "MESH:D041981", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C34082" }, { @@ -26475,7 +29022,13 @@ }, { "val" : "TGMA:0001819" }, { - "val" : "UMLS:C0017189" + "val" : "UMLS:C0017189", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrointestinal_Tract" + } ] + } }, { "val" : "VHOG:0000309" }, { @@ -26487,10 +29040,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1371/journal.pone.0016309" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -26515,7 +29080,13 @@ "xrefs" : [ "ZFA:0005145" ] } ], "xrefs" : [ { - "val" : "EMAPA:37474" + "val" : "EMAPA:37474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100146" }, { @@ -26605,7 +29176,13 @@ }, { "val" : "TAO:0000005" }, { - "val" : "UMLS:C0003842" + "val" : "UMLS:C0003842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Artery" + } ] + } }, { "val" : "VHOG:0001251" }, { @@ -26694,7 +29271,13 @@ }, { "val" : "TAO:0000082" }, { - "val" : "UMLS:C0042449" + "val" : "UMLS:C0042449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vein" + } ] + } }, { "val" : "VHOG:0001743" }, { @@ -26765,7 +29348,13 @@ }, { "val" : "NCIT:C13356" }, { - "val" : "UMLS:C0032105" + "val" : "UMLS:C0032105", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Plasma" + } ] + } }, { "val" : "Wikipedia:Blood_plasma" } ], @@ -26807,7 +29396,13 @@ }, { "val" : "TAO:0005315" }, { - "val" : "UMLS:C0042520" + "val" : "UMLS:C0042520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venule" + } ] + } }, { "val" : "VHOG:0001765" }, { @@ -26861,7 +29456,13 @@ }, { "val" : "TAO:0002138" }, { - "val" : "UMLS:C0003847" + "val" : "UMLS:C0003847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Arteriole" + } ] + } }, { "val" : "VHOG:0001763" }, { @@ -26944,7 +29545,13 @@ }, { "val" : "TAO:0002137" }, { - "val" : "UMLS:C0005847" + "val" : "UMLS:C0005847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel" + } ] + } }, { "val" : "VHOG:0001250" }, { @@ -27010,7 +29617,13 @@ }, { "val" : "TAO:0005250" }, { - "val" : "UMLS:C0935624" + "val" : "UMLS:C0935624", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary" + } ] + } }, { "val" : "VHOG:0001253" }, { @@ -27065,7 +29678,13 @@ }, { "val" : "SCTID:27168002" }, { - "val" : "UMLS:C0014257" + "val" : "UMLS:C0014257", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endothelium" + } ] + } }, { "val" : "galen:Endothelium" } ], @@ -27157,7 +29776,13 @@ }, { "val" : "EFO:0000461" }, { - "val" : "FBbt:00004208" + "val" : "FBbt:00004208", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69067" }, { @@ -27173,7 +29798,13 @@ }, { "val" : "TAO:0001105" }, { - "val" : "UMLS:C0013948" + "val" : "UMLS:C0013948", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Structure" + } ] + } }, { "val" : "VSAO:0000178" }, { @@ -27237,7 +29868,13 @@ }, { "val" : "SCTID:118760003" }, { - "val" : "UMLS:C0042779" + "val" : "UMLS:C0042779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Viscera" + } ] + } }, { "val" : "Wikipedia:Viscus" }, { @@ -27276,7 +29913,13 @@ }, { "val" : "EHDAA:5049" }, { - "val" : "EMAPA:37721" + "val" : "EMAPA:37721", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71221" }, { @@ -27284,7 +29927,13 @@ }, { "val" : "MAT:0000148" }, { - "val" : "MESH:D013131" + "val" : "MESH:D013131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000148" }, { @@ -27358,7 +30007,13 @@ }, { "val" : "TAO:0001115" }, { - "val" : "UMLS:C0460005" + "val" : "UMLS:C0460005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trunk" + } ] + } }, { "val" : "Wikipedia:Torso" }, { @@ -27445,7 +30100,13 @@ }, { "val" : "SCTID:278858007" }, { - "val" : "UMLS:C0026860" + "val" : "UMLS:C0026860", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Musculoskeletal_System" + } ] + } }, { "val" : "VHOG:0001275" }, { @@ -27571,7 +30232,13 @@ }, { "val" : "SCTID:243949006" }, { - "val" : "UMLS:C0230139" + "val" : "UMLS:C0230139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Thoracic_Cavity" + } ] + } }, { "val" : "Wikipedia:Thoracic_cavity" } ], @@ -27643,7 +30310,13 @@ }, { "val" : "EHDAA2:0000267" }, { - "val" : "FBbt:00005060" + "val" : "FBbt:00005060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85006" }, { @@ -27655,7 +30328,13 @@ }, { "val" : "TAO:0001438" }, { - "val" : "UMLS:C0333343" + "val" : "UMLS:C0333343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cavity" + } ] + } }, { "val" : "galen:BodyCavity" } ], @@ -27719,7 +30398,13 @@ }, { "val" : "TAO:0000135" }, { - "val" : "UMLS:C0028439" + "val" : "UMLS:C0028439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochord" + } ] + } }, { "val" : "VHOG:0000199" }, { @@ -27815,7 +30500,13 @@ }, { "val" : "TAO:0000155" }, { - "val" : "UMLS:C0376449" + "val" : "UMLS:C0376449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somite" + } ] + } }, { "val" : "VHOG:0000191" }, { @@ -27827,7 +30518,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:17237766" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somite" @@ -27864,7 +30561,13 @@ }, { "val" : "NCIT:C12957" }, { - "val" : "UMLS:C1516995" + "val" : "UMLS:C1516995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_System" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" }, { @@ -27929,7 +30632,13 @@ }, { "val" : "SCTID:361462002" }, { - "val" : "UMLS:C0027789" + "val" : "UMLS:C0027789", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Crest" + } ] + } }, { "val" : "VHOG:0000057" }, { @@ -28001,7 +30710,13 @@ }, { "val" : "EV:0100004" }, { - "val" : "FBbt:00001057" + "val" : "FBbt:00001057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:87657" }, { @@ -28013,7 +30728,13 @@ }, { "val" : "TAO:0001120" }, { - "val" : "UMLS:C1518271" + "val" : "UMLS:C1518271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neuroectoderm" + } ] + } }, { "val" : "VHOG:0000150" }, { @@ -28071,7 +30792,13 @@ }, { "val" : "SCTID:115976003" }, { - "val" : "UMLS:C0015282" + "val" : "UMLS:C0015282", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" } ], @@ -28142,7 +30869,13 @@ }, { "val" : "SCTID:421320006" }, { - "val" : "UMLS:C0005953" + "val" : "UMLS:C0005953", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bone_Marrow" + } ] + } }, { "val" : "VHOG:0001218" }, { @@ -28217,7 +30950,13 @@ }, { "val" : "TAO:0001641" }, { - "val" : "UMLS:C0009780" + "val" : "UMLS:C0009780", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Connective_Tissue" + } ] + } }, { "val" : "VSAO:0000017" }, { @@ -28285,7 +31024,13 @@ }, { "val" : "SCTID:91727004" }, { - "val" : "UMLS:C2328219" + "val" : "UMLS:C2328219", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle_Tissue" + } ] + } }, { "val" : "Wikipedia:Muscle_tissue" }, { @@ -28363,7 +31108,13 @@ }, { "val" : "TAO:0005023" }, { - "val" : "UMLS:C0018957" + "val" : "UMLS:C0018957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hematopoietic_System" + } ] + } }, { "val" : "VHOG:0001624" }, { @@ -28412,7 +31163,13 @@ }, { "val" : "TAO:0001159" }, { - "val" : "UMLS:C0020962" + "val" : "UMLS:C0020962", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Immune_System" + } ] + } }, { "val" : "VHOG:0001247" }, { @@ -28476,7 +31233,13 @@ }, { "val" : "NCIT:C13076" }, { - "val" : "UMLS:C0391978" + "val" : "UMLS:C0391978", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bone_Tissue" + } ] + } }, { "val" : "VSAO:0000047" }, { @@ -28535,7 +31298,13 @@ }, { "val" : "EMAPA:18425" }, { - "val" : "FBbt:00100317" + "val" : "FBbt:00100317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7146" }, { @@ -28553,7 +31322,13 @@ }, { "val" : "SCTID:134358001" }, { - "val" : "UMLS:C1285092" + "val" : "UMLS:C1285092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gland" + } ] + } }, { "val" : "Wikipedia:Gland" }, { @@ -28641,7 +31416,13 @@ "xrefs" : [ { "val" : "BIRNLEX:1011" }, { - "val" : "EMAPA:37442" + "val" : "EMAPA:37442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67552" }, { @@ -28759,7 +31540,13 @@ }, { "val" : "TE:E5.11.2.0.0.0.4" }, { - "val" : "UMLS:C1511224" + "val" : "UMLS:C1511224", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Island" + } ] + } }, { "val" : "VHOG:0000085" }, { @@ -28854,7 +31641,13 @@ }, { "val" : "TAO:0000132" }, { - "val" : "UMLS:C0920623" + "val" : "UMLS:C0920623", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Plate" + } ] + } }, { "val" : "VHOG:0000068" }, { @@ -28915,7 +31708,13 @@ }, { "val" : "TAO:0000255" }, { - "val" : "UMLS:C1284009" + "val" : "UMLS:C1284009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Paraxial_Mesoderm" + } ] + } }, { "val" : "VHOG:0000114" }, { @@ -28982,7 +31781,13 @@ }, { "val" : "TAO:0000121" }, { - "val" : "UMLS:C1517749" + "val" : "UMLS:C1517749", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lateral_Mesoderm" + } ] + } }, { "val" : "VHOG:0000118" }, { @@ -29027,7 +31832,13 @@ }, { "val" : "TAO:0000028" }, { - "val" : "UMLS:C1514450" + "val" : "UMLS:C1514450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium_of_the_Heart" + } ] + } }, { "val" : "XAO:0000336" }, { @@ -29077,7 +31888,13 @@ }, { "val" : "TAO:0001080" }, { - "val" : "UMLS:C0183176" + "val" : "UMLS:C0183176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclerotome" + } ] + } }, { "val" : "VHOG:0000680" }, { @@ -29184,7 +32001,13 @@ }, { "val" : "TAO:0000393" }, { - "val" : "UMLS:C0162415" + "val" : "UMLS:C0162415", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesenchyme" + } ] + } }, { "val" : "VHOG:0000170" }, { @@ -29270,7 +32093,13 @@ }, { "val" : "NCIT:C34195" }, { - "val" : "UMLS:C1512940" + "val" : "UMLS:C1512940", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intraembryonic_Coelom" + } ] + } }, { "val" : "VHOG:0000316" }, { @@ -29302,7 +32131,13 @@ }, { "val" : "EHDAA2:0003114" }, { - "val" : "FBbt:00007474" + "val" : "FBbt:00007474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -29731,7 +32566,13 @@ }, { "val" : "TAO:0000010" }, { - "val" : "UMLS:C0007226" + "val" : "UMLS:C0007226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiovascular_System" + } ] + } }, { "val" : "VHOG:0000302" }, { @@ -29857,7 +32698,13 @@ }, { "val" : "SCTID:362060003" }, { - "val" : "UMLS:C1267406" + "val" : "UMLS:C1267406", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venous_System" + } ] + } }, { "val" : "VHOG:0000277" } ], @@ -29889,7 +32736,13 @@ }, { "val" : "TAO:0005257" }, { - "val" : "UMLS:C1706972" + "val" : "UMLS:C1706972", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel_Endothelium" + } ] + } }, { "val" : "ZFA:0005257" } ], @@ -29927,7 +32780,13 @@ }, { "val" : "NCIT:C34131" }, { - "val" : "UMLS:C1516779" + "val" : "UMLS:C1516779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conceptus" + } ] + } }, { "val" : "Wikipedia:Conceptus" } ], @@ -29991,7 +32850,13 @@ }, { "val" : "BTO:0001403" }, { - "val" : "FBbt:00005317" + "val" : "FBbt:00005317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:293108" }, { @@ -30005,9 +32870,21 @@ }, { "val" : "NCIT:C34058" }, { - "val" : "UMLS:C0017199" - }, { - "val" : "UMLS:C1284022" + "val" : "UMLS:C0017199", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrula" + } ] + } + }, { + "val" : "UMLS:C1284022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trilaminar_Embryonic_Disc" + } ] + } }, { "val" : "Wikipedia:Gastrula" }, { @@ -30029,7 +32906,13 @@ }, "comments" : [ "Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from" ], "xrefs" : [ { - "val" : "EMAPA:37744" + "val" : "EMAPA:37744", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0003047" }, { @@ -30151,7 +33034,13 @@ }, { "val" : "TAO:0002171" }, { - "val" : "UMLS:C0014261" + "val" : "UMLS:C0014261", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_Endothelium" + } ] + } }, { "val" : "VHOG:0001217" }, { @@ -30260,7 +33149,13 @@ "val" : "joint" } ], "xrefs" : [ { - "val" : "FBbt:00005811" + "val" : "FBbt:00005811", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -30297,7 +33192,13 @@ "xrefs" : [ "FMA:71131" ] } ], "xrefs" : [ { - "val" : "FBbt:00100315" + "val" : "FBbt:00100315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:71131" } ], @@ -30350,7 +33251,13 @@ }, { "val" : "SCTID:361463007" }, { - "val" : "UMLS:C0814992" + "val" : "UMLS:C0814992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Groove" + } ] + } }, { "val" : "Wikipedia:Neural_groove" }, { @@ -30387,7 +33294,13 @@ }, { "val" : "SCTID:361461009" }, { - "val" : "UMLS:C0814993" + "val" : "UMLS:C0814993", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Fold" + } ] + } }, { "val" : "Wikipedia:Neural_fold" }, { @@ -30485,7 +33398,13 @@ "xrefs" : [ "MA:0000516" ] } ], "xrefs" : [ { - "val" : "EMAPA:37270" + "val" : "EMAPA:37270", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000516" } ], @@ -30510,7 +33429,13 @@ "xrefs" : [ "MA:0000557" ] } ], "xrefs" : [ { - "val" : "EMAPA:37273" + "val" : "EMAPA:37273", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000557" } ], @@ -30535,7 +33460,13 @@ "xrefs" : [ "MA:0000563" ] } ], "xrefs" : [ { - "val" : "EMAPA:37271" + "val" : "EMAPA:37271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000563" } ], @@ -30629,7 +33560,13 @@ }, { "val" : "EHDAA2:0003125" }, { - "val" : "FBbt:00007006" + "val" : "FBbt:00007006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:292313" }, { @@ -30753,13 +33690,25 @@ }, { "val" : "SCTID:68989006" }, { - "val" : "UMLS:C0004799" + "val" : "UMLS:C0004799", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Basement_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "http://palaeos.com/metazoa/porifera/homoscleromorpha.html" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "basement membrane of epithelium" @@ -30818,7 +33767,13 @@ }, { "val" : "SCTID:361725000" }, { - "val" : "UMLS:C0222645" + "val" : "UMLS:C0222645", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Axial_Skeleton" + } ] + } }, { "val" : "VSAO:0000056" }, { @@ -30862,7 +33817,13 @@ }, { "val" : "NCIT:C34231" }, { - "val" : "UMLS:C1518429" + "val" : "UMLS:C1518429", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Plate" + } ] + } }, { "val" : "VHOG:0001212" } ], @@ -30903,7 +33864,13 @@ }, { "val" : "NCIT:C34232" }, { - "val" : "UMLS:C1518430" + "val" : "UMLS:C1518430", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Process" + } ] + } }, { "val" : "VHOG:0001213" } ], @@ -30933,7 +33900,13 @@ "xrefs" : [ { "val" : "BIRNLEX:20" }, { - "val" : "EMAPA:37441" + "val" : "EMAPA:37441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:280556" }, { @@ -31101,7 +34074,13 @@ }, { "val" : "SCTID:40118003" }, { - "val" : "UMLS:C0221909" + "val" : "UMLS:C0221909", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Squamous_epithelium" } ], @@ -31154,7 +34133,13 @@ }, { "val" : "NCIT:C34022" }, { - "val" : "UMLS:C1515977" + "val" : "UMLS:C1515977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Surface" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -31273,7 +34258,13 @@ }, { "val" : "SCTID:360394002" }, { - "val" : "UMLS:C1514442" + "val" : "UMLS:C1514442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordial_Gut" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -31624,7 +34615,13 @@ }, { "val" : "EHDAA2:0003170" }, { - "val" : "FBbt:00005426" + "val" : "FBbt:00005426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "Wikipedia:Anlage_(biology)" } ], @@ -31711,7 +34708,13 @@ }, { "val" : "NCIT:C33854" }, { - "val" : "UMLS:C0489903" + "val" : "UMLS:C0489903", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_System" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -31868,7 +34871,13 @@ "xrefs" : [ { "val" : "CARO:0010000" }, { - "val" : "FBbt:00100313" + "val" : "FBbt:00100313", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -32126,7 +35135,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007330" + "val" : "FBbt:00007330", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67509" }, { @@ -32192,7 +35207,13 @@ "val" : "main body segment" } ], "xrefs" : [ { - "val" : "FBbt:00057001" + "val" : "FBbt:00057001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -32247,7 +35268,13 @@ }, { "val" : "NCIT:C32450" }, { - "val" : "UMLS:C1511770" + "val" : "UMLS:C1511770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Dense_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Dense_connective_tissue" } ], @@ -32338,7 +35365,13 @@ "val" : "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "coelom" @@ -32405,7 +35438,13 @@ }, { "val" : "NCIT:C13051" }, { - "val" : "UMLS:C0229619" + "val" : "UMLS:C0229619", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hematopoietic_Tissue" + } ] + } } ] } }, { @@ -32615,7 +35654,13 @@ "xrefs" : [ { "val" : "AEO:0000093" }, { - "val" : "FBbt:00007278" + "val" : "FBbt:00007278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -32680,7 +35725,13 @@ "xrefs" : [ "MA:0002449" ] } ], "xrefs" : [ { - "val" : "EMAPA:37597" + "val" : "EMAPA:37597", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002449" } ], @@ -32863,7 +35914,13 @@ "xrefs" : [ { "val" : "CARO:0020000" }, { - "val" : "FBbt:00007276" + "val" : "FBbt:00007276", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -34583,7 +37640,13 @@ "meta" : { "definition" : { "val" : "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -34599,7 +37662,13 @@ "meta" : { "definition" : { "val" : "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -34999,7 +38068,7 @@ } }, { "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym", - "lbl" : "has_narrow_synonym", + "lbl" : "has narrow synonym", "type" : "PROPERTY", "propertyType" : "ANNOTATION", "meta" : { @@ -35118,22 +38187,18 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000007", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0002321" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0011115" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", - "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0017145" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000037", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000037", "pred" : "is_a", @@ -35348,6 +38413,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000076", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000066" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000076", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000077", "pred" : "is_a", @@ -35902,6 +38971,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000219" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000333", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", @@ -36520,6 +39593,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000647", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", "obj" : "http://purl.obolibrary.org/obo/CL_0000235" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000680", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000680", "pred" : "is_a", @@ -38106,6 +41183,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0007004", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", @@ -38150,10 +41231,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0011026", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", @@ -39088,7 +42165,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0032991" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005581", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "pred" : "http://purl.obolibrary.org/obo/RO_0002160", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005587", @@ -39186,6 +42263,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0005773", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/GO_0005737" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0005773", + "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2759" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005794", "pred" : "is_a", @@ -39198,10 +42279,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0005794", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/GO_0012505" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0005794", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", - "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2759" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005840", "pred" : "is_a", @@ -39678,6 +42755,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008015", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/GO_0003013" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0008150", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", + "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -42390,6 +45471,10 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33154" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "pred" : "is_a", @@ -42602,6 +45687,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0001579", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0001591", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0000052" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0001690", "pred" : "is_a", @@ -42682,6 +45771,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002198", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0002254", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001591" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002266", "pred" : "is_a", @@ -47803,6 +50896,13 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0001981" } ] + }, { + "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000076", + "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], + "restrictions" : [ { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002254" + } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000080", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000000" ], @@ -51597,6 +54697,13 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" } ] + }, { + "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", + "allValuesFromEdges" : [ { + "sub" : "http://purl.obolibrary.org/obo/GO_0005581", + "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062", "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], diff --git a/subsets/blood_and_immune_upper_slim.obo b/subsets/blood_and_immune_upper_slim.obo index 83866bf00..84987c74c 100644 --- a/subsets/blood_and_immune_upper_slim.obo +++ b/subsets/blood_and_immune_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2025-12-17/subsets/blood_and_immune_upper_slim.owl +data-version: cl/releases/2026-03-17/subsets/blood_and_immune_upper_slim.owl idspace: dc http://purl.org/dc/elements/1.1/ idspace: foaf http://xmlns.com/foaf/0.1/ idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# @@ -7,7 +7,7 @@ idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: terms http://purl.org/dc/terms/ ontology: cl/subsets/blood_and_immune_upper_slim -property_value: owl:versionInfo "2025-12-17" xsd:string +property_value: owl:versionInfo "2026-03-17" xsd:string [Term] id: BFO:0000002 @@ -78,21 +78,18 @@ property_value: skos:prefLabel "early embryonic cell (metazoa)" xsd:string id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] -comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset -synonym: "animal stem cell" EXACT [] +synonym: "animal stem cell" NARROW [] xref: CALOHA:TS-2086 xref: FMA:63368 xref: ZFA:0005957 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa relationship: RO:0002215 GO:0017145 ! capable of stem cell division property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000034" xsd:string {name="stem cell on CELLxGENE CellGuide"} @@ -119,6 +116,7 @@ xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 xref: ZFA:0009014 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell @@ -407,13 +405,18 @@ property_value: terms:description "Blood vessel endothelial cells, also known as [Term] id: CL:0000076 name: squamous epithelial cell +def: "An epithelial cell that has a flattened morphology." [] subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: CALOHA:TS-1249 xref: ZFA:0009039 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell +intersection_of: CL:0000066 ! epithelial cell +intersection_of: RO:0000053 PATO:0002254 ! has characteristic flattened +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: skos:prefLabel "squamous epithelial cell" xsd:string +property_value: terms:date "2025-12-16T15:56:39Z" xsd:dateTime [Term] id: CL:0000077 @@ -754,6 +757,7 @@ name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset subset: general_cell_types_upper_slim +subset: human_reference_atlas subset: human_subset subset: mouse_subset synonym: "muscle fiber" EXACT [] @@ -771,6 +775,7 @@ is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell relationship: RO:0002202 CL:0000056 ! develops from myoblast property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI +property_value: RO:0002175 NCBITaxon:9606 property_value: skos:prefLabel "muscle cell" xsd:string [Term] @@ -1086,6 +1091,7 @@ subset: mouse_subset xref: FMA:86667 xref: ZFA:0007086 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell @@ -1691,6 +1697,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009291 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell @@ -1728,6 +1735,7 @@ subset: human_subset subset: mouse_subset synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] +synonym: "WBC" EXACT OMO:0003000 [PMID:40794848] synonym: "white blood cell" EXACT [] xref: BTO:0000751 xref: CALOHA:TS-0549 @@ -3278,6 +3286,7 @@ subset: human_subset subset: mouse_subset xref: ZFA:0007084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: BFO:0000002 +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell @@ -3344,7 +3353,6 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset is_a: BFO:0000002 -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002202 CL:0000034 ! develops from stem cell @@ -3475,6 +3483,7 @@ def: "A leukocyte with a single non-segmented nucleus in the mature form found i subset: cellxgene_subset subset: human_subset subset: mouse_subset +synonym: "PBMC" EXACT OMO:0003000 [PMID:27696124] is_a: CL:0000080 ! circulating cell is_a: CL:0000842 ! mononuclear leukocyte intersection_of: CL:0000842 ! mononuclear leukocyte @@ -3527,6 +3536,7 @@ is_a: GO:0140096 ! catalytic activity, acting on a protein is_a: GO:0140101 ! catalytic activity, acting on a tRNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0000262 @@ -4628,6 +4638,7 @@ subset: goslim_yeast synonym: "molecular function" EXACT [] disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process +property_value: IAO:0000116 "This is the same as GO molecular function" xsd:string [Term] id: GO:0003824 @@ -4707,6 +4718,9 @@ synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 +union_of: GO:0032991 ! protein-containing complex +union_of: GO:0044423 ! virion component +union_of: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0008150 ! biological_process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI @@ -4755,7 +4769,8 @@ namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa +relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa +relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0005587 @@ -4993,6 +5008,7 @@ synonym: "vacuolar carboxypeptidase Y" RELATED [] xref: Wikipedia:Vacuole is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: BFO:0000050 GO:0005737 ! part of cytoplasm +relationship: RO:0002162 NCBITaxon:2759 ! in taxon Eukaryota [Term] id: GO:0005794 @@ -5019,7 +5035,6 @@ xref: Wikipedia:Golgi_apparatus is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: BFO:0000050 GO:0005737 ! part of cytoplasm relationship: BFO:0000050 GO:0012505 ! part of endomembrane system -relationship: RO:0002162 NCBITaxon:2759 ! in taxon Eukaryota property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14798" xsd:anyURI [Term] @@ -5829,6 +5844,7 @@ synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process +relationship: BFO:0000051 GO:0003674 ! has part molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI creation_date: 2012-09-19T15:05:24Z @@ -6445,10 +6461,10 @@ subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" -xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016746 @@ -6465,6 +6481,7 @@ xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurin xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" is_a: GO:0016740 ! transferase activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016755 @@ -6474,6 +6491,7 @@ def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) synonym: "transferase activity, transferring amino-acyl groups" EXACT [] xref: EC:2.3.2.- is_a: GO:0016746 ! acyltransferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0017145 @@ -6744,6 +6762,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] @@ -6752,6 +6771,7 @@ is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] @@ -6759,6 +6779,7 @@ id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:18391171] +subset: gocheck_do_not_annotate synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly @@ -6766,6 +6787,7 @@ is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI [Term] id: GO:0030054 @@ -7375,6 +7397,7 @@ is_a: GO:0005575 ! cellular_component disjoint_from: GO:0044423 ! virion component disjoint_from: GO:0110165 ! cellular anatomical structure relationship: BFO:0000051 PR:000000001 ! has part protein +property_value: IAO:0000116 "This is not covalently bonded, which conflicts with changes to the parent definition." xsd:string [Term] id: GO:0033151 @@ -7739,7 +7762,7 @@ property_value: RO:0002161 NCBITaxon:4751 id: GO:0042592 name: homeostatic process namespace: biological_process -def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] +def: "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." [PMID:26265027] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse @@ -7750,6 +7773,7 @@ synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological_process +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31175" xsd:anyURI [Term] id: GO:0042611 @@ -7831,6 +7855,7 @@ id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon @@ -7843,6 +7868,7 @@ synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: BFO:0000050 CL:0000000 ! part of cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: skos:prefLabel "cell projection" xsd:string [Term] @@ -9532,15 +9558,16 @@ def: "A collagen trimer that forms networks." [PMID:21421911] is_a: BFO:0000004 is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer -intersection_of: BFO:0000050 GO:0098645 ! part of collagen network -relationship: BFO:0000050 GO:0098645 ! part of collagen network +intersection_of: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens +relationship: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens [Term] id: GO:0098643 -name: fibrillar collagen +name: fibrillar collagen complex namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175] synonym: "banded collagen fibril" EXACT [] +synonym: "fibrillar collagen" EXACT [] is_a: GO:0098644 ! complex of collagen trimers relationship: BFO:0000050 GO:0140152 ! part of collagenous component of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI @@ -9561,10 +9588,12 @@ property_value: skos:prefLabel "complex of collagen trimers" xsd:string [Term] id: GO:0098645 -name: collagen network +name: complex of network-forming collagens namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] +synonym: "collagen network" EXACT [] is_a: GO:0098644 ! complex of collagen trimers +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30938" xsd:anyURI [Term] id: GO:0098657 @@ -9715,6 +9744,8 @@ subset: goslim_pir synonym: "cellular anatomical entity" EXACT [] is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure +property_value: IAO:0000116 "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." xsd:string +property_value: IAO:0000116 "Overlaps with some cellular components from GO" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28978" xsd:anyURI @@ -9881,7 +9912,7 @@ id: GO:0140154 name: chicken-wire-like collagen network namespace: cellular_component def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942] -is_a: GO:0098645 ! collagen network +is_a: GO:0098645 ! complex of network-forming collagens relationship: BFO:0000050 GO:0140143 ! part of collagenous component of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI @@ -10287,6 +10318,22 @@ xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: skos:prefLabel "Eukaryota" xsd:string +[Term] +id: NCBITaxon:28009 +name: Choanoflagellata +namespace: ncbi_taxonomy +synonym: "Choanoflagellatea" RELATED synonym [] +synonym: "choanoflagellates" EXACT genbank_common_name [] +synonym: "choanoflagellates" RELATED blast_name [] +synonym: "Choanoflagellida" RELATED synonym [] +synonym: "Choanomonada" RELATED synonym [] +synonym: "Choanozoa" RELATED synonym [] +xref: GC_ID:1 +xref: PMID:27765632 +is_a: NCBITaxon:33154 ! Opisthokonta +disjoint_from: NCBITaxon:33208 ! Metazoa +disjoint_from: NCBITaxon:4751 ! Fungi + [Term] id: NCBITaxon:314146 name: Euarchontoglires @@ -10809,6 +10856,14 @@ subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality +[Term] +id: PATO:0001591 +name: curvature +namespace: quality +def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] +subset: attribute_slim +is_a: PATO:0000052 ! shape + [Term] id: PATO:0001690 name: contractile @@ -10984,6 +11039,18 @@ is_a: PATO:0001018 ! physical quality property_value: terms:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-03-15T04:35:27Z +[Term] +id: PATO:0002254 +name: flattened +namespace: quality +def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] +comment: Becoming flat but not necessarily completely flat. +subset: value_slim +synonym: "compressed" RELATED [] +is_a: PATO:0001591 ! curvature +property_value: terms:contributor https://orcid.org/0000-0002-2061-091X +creation_date: 2010-08-16T03:59:34Z + [Term] id: PATO:0002266 name: 3-D shape @@ -17833,7 +17900,7 @@ xref: NCIT:C32339 xref: NIF_Subcellular:sao7547390221 is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: RO:0002473 GO:0005581 ! composed primarily of collagen trimer -relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen +relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen complex property_value: seeAlso UBERON:0007377 property_value: skos:prefLabel "collection of collagen fibrils" xsd:string diff --git a/subsets/blood_and_immune_upper_slim.owl b/subsets/blood_and_immune_upper_slim.owl index 415de6f78..0908a8dba 100644 --- a/subsets/blood_and_immune_upper_slim.owl +++ b/subsets/blood_and_immune_upper_slim.owl @@ -14,8 +14,8 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - - 2025-12-17 + + 2026-03-17 @@ -257,7 +257,6 @@ WHERE { An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has narrow synonym - has_narrow_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/19 @@ -2715,14 +2714,7 @@ Each of these 3 primitives can be composed to yield a cross-product of different - - - - - - - @@ -2739,13 +2731,12 @@ Stem cells have numerous potential applications in medicine, including the treat CALOHA:TS-2086 FMA:63368 ZFA:0005957 - animal stem cell + animal stem cell - This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. stem cell https://cellxgene.cziscience.com/cellguide/CL_0000034 stem cell @@ -2852,6 +2843,7 @@ Stem cells have numerous potential applications in medicine, including the treat + @@ -3827,7 +3819,26 @@ Blood vessel endothelial cells are sensitive to various stimuli, including shear + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -5054,6 +5065,7 @@ APCs are responsible for stimulating an appropriate immune response. Following a A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -5067,6 +5079,7 @@ APCs are responsible for stimulating an appropriate immune response. Following a + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -6024,6 +6037,7 @@ Tissue-resident macrophages are diverse and heterogenous, likely as a result of + @@ -8275,6 +8289,7 @@ Beyond their role in fighting infections, monocytes play an important role in th + @@ -8460,6 +8475,7 @@ Somatic stem cells respond to environmental signals that regulate their quiescen MESH:D007962 NCIT:C12529 ZFA:0009309 + WBC leucocyte white blood cell immune cell @@ -8489,6 +8505,13 @@ Somatic stem cells respond to environmental signals that regulate their quiescen ZFA:0009309 + + + + WBC + PMID:40794848 + + @@ -13665,6 +13688,7 @@ The balance between cell proliferation and differentiation in embryonic cells is + @@ -13855,7 +13879,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -14237,6 +14260,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. 2014-02-11T17:29:04Z + PBMC CL:2000001 @@ -14249,6 +14273,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. GOC:TermGenie + + + + PBMC + PMID:27696124 + + @@ -14352,6 +14383,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. https://github.com/geneontology/go-ontology/issues/22192 https://github.com/geneontology/go-ontology/issues/25493 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.12 MetaCyc:PEPTIDYLTRANSFERASE-RXN Reactome:R-HSA-156912 @@ -17515,6 +17547,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. + This is the same as GO molecular function molecular function molecular_function GO:0003674 @@ -17698,6 +17731,15 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + @@ -17817,10 +17859,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component @@ -18314,6 +18362,12 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. Wikipedia:Vacuole cellular_component @@ -18359,12 +18413,6 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - - - - - A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. https://github.com/geneontology/go-ontology/issues/14798 Golgi @@ -20473,6 +20521,12 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. https://github.com/geneontology/go-ontology/issues/24968 2012-09-19T15:05:24Z @@ -20711,6 +20765,30 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + + + + + + + + + + + + + + + A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. @@ -20759,6 +20837,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + @@ -20829,6 +20917,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + @@ -20899,6 +20997,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + @@ -20935,6 +21043,70 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. @@ -21997,10 +22169,10 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + https://github.com/geneontology/go-ontology/issues/30193 EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 - Reactome:R-HSA-5333607 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function @@ -22035,12 +22207,6 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 - - - - Reactome:R-HSA-5333607 - GSSeH combines with bGalNAc derivative to form GSSebGalNac - @@ -22062,6 +22228,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 @@ -22112,6 +22279,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function @@ -22859,12 +23027,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 https://github.com/geneontology/go-ontology/issues/26279 cell projection organisation biological_process cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 + cell projection organization @@ -22914,10 +23084,12 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 formation of a cell surface projection biological_process cell projection biogenesis GO:0030031 + cell projection assembly @@ -24585,6 +24757,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + This is not covalently bonded, which conflicts with changes to the parent definition. macromolecular complex macromolecule complex protein containing complex @@ -25688,7 +25861,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - Any biological process involved in the maintenance of an internal steady state. + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + https://github.com/geneontology/go-ontology/issues/31175 homeostasis activation of homeostatic process inhibition of homeostatic process @@ -25705,9 +25879,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - Any biological process involved in the maintenance of an internal steady state. - GOC:jl - ISBN:0395825172 + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + PMID:26265027 @@ -25859,6 +26032,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + @@ -25967,11 +26150,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 cell process cellular process cellular projection cellular_component GO:0042995 + @@ -30666,9 +30851,10 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac https://github.com/geneontology/go-ontology/issues/29474 https://github.com/geneontology/go-ontology/issues/30146 banded collagen fibril + fibrillar collagen cellular_component GO:0098643 - fibrillar collagen + fibrillar collagen complex fibrillar collagen @@ -30733,9 +30919,11 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A supramolecular complex that consists of collagen triple helices associated to form a network. + https://github.com/geneontology/go-ontology/issues/30938 + collagen network cellular_component GO:0098645 - collagen network + complex of network-forming collagens @@ -31197,6 +31385,9 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes. + Overlaps with some cellular components from GO https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 https://github.com/geneontology/go-ontology/issues/28978 @@ -32787,6 +32978,63 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + GC_ID:1 + PMID:27765632 + choanoflagellates + ncbi_taxonomy + Choanoflagellatea + Choanoflagellida + Choanomonada + Choanozoa + choanoflagellates + NCBITaxon:28009 + Choanoflagellata + + + + + choanoflagellates + + + + + + Choanoflagellatea + + + + + + Choanoflagellida + + + + + + Choanomonada + + + + + + Choanozoa + + + + + + choanoflagellates + + + + + @@ -33958,6 +34206,25 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + quality + PATO:0001591 + + curvature + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + WordNet:WordNet + + + + @@ -34341,6 +34608,29 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + + 2010-08-16T03:59:34Z + quality + compressed + PATO:0002254 + + Becoming flat but not necessarily completely flat. + flattened + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + PATOC:CVS + + + + @@ -39175,7 +39465,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -39186,14 +39476,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac membrane organ membrane organ - + - + FMA-def @@ -39962,7 +40252,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -40004,14 +40294,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac gastrula stage gastrula stage - + - + BILS @@ -40496,15 +40786,15 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + - - + + A fluid that is composed of blood plasma and erythrocytes. @@ -40543,34 +40833,34 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac blood blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -42301,7 +42591,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. AAO:0000137 BILA:0000036 @@ -42336,14 +42626,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -42383,7 +42673,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. AAO:0000139 BILA:0000038 @@ -42418,14 +42708,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -42466,7 +42756,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The middle germ layer of the embryo, between the endoderm and ectoderm. AAO:0000304 @@ -42506,14 +42796,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + - + Bgee:AN @@ -42681,7 +42971,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -42746,14 +43036,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb - + - + MA @@ -43167,7 +43457,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -43218,14 +43508,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -43285,7 +43575,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. @@ -43330,7 +43620,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac central nervous system central nervous system - + @@ -43344,7 +43634,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Bgee:AN @@ -43715,7 +44005,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -43740,14 +44030,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -43880,13 +44170,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + - + Skeletal element that is composed of bone tissue. @@ -43928,14 +44218,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac bone element bone element - + - + VSAO-modified @@ -44089,7 +44379,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + A tube extending from the mouth to the anus. @@ -44127,14 +44417,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac digestive tract digestive tract - + - + NCBIBook:NBK10107 @@ -44692,8 +44982,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + @@ -44706,7 +44996,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -44760,34 +45050,34 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -45660,7 +45950,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -45696,14 +45986,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac coelemic cavity lumen coelemic cavity lumen - + - + definitional @@ -45799,8 +46089,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + @@ -45850,11 +46140,11 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -45873,13 +46163,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + ZFA - + EHDAA2 @@ -45920,7 +46210,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. mesodermal cluster @@ -45958,7 +46248,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -45971,7 +46261,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + ZFA @@ -46090,16 +46380,16 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - - + + + - + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. AAO:0010578 BTO:0001764 @@ -46132,45 +46422,45 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + BTO - + PMID:11523831 - + PMID:11523831 @@ -46389,7 +46679,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -46444,14 +46734,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac bone marrow http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg - + - + FMA MA @@ -46659,8 +46949,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + Anatomical system that is involved in the production of hematopoietic cells. @@ -46701,24 +46991,24 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac hematopoietic system hematopoietic system - + - + - + FMA - + definitional @@ -47102,7 +47392,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -47121,7 +47411,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. AAO:0011086 EFO:0001982 @@ -47144,14 +47434,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac presomitic mesoderm presomitic mesoderm - + - + Bgee:AN @@ -47307,8 +47597,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. AAO:0011072 BTO:0001765 @@ -47337,24 +47627,24 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + Wikipedia - + Bgee:AN @@ -47400,7 +47690,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. AAO:0010568 EFO:0003515 @@ -47426,7 +47716,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -47439,7 +47729,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Bgee:AN @@ -47486,7 +47776,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -47525,7 +47815,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -47538,7 +47828,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + EHDAA2 VHOG @@ -47589,15 +47879,15 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. AAO:0011044 @@ -47614,15 +47904,15 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac heart primordium heart primordium - + - + - + @@ -47635,19 +47925,19 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + ZFA - + ZFA - + XAO @@ -47676,8 +47966,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. AAO:0010571 AEO:0000212 @@ -47701,11 +47991,11 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -47724,13 +48014,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + VHOG:0000680 - + ZFA @@ -47983,7 +48273,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults EHDAA:251 @@ -47998,14 +48288,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac intraembryonic coelom intraembryonic coelom - + - + Wikipedia @@ -48363,8 +48653,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. XAO:0004185 first heart field @@ -48376,24 +48666,24 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac primary heart field primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -48446,7 +48736,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + An epithelial tube that will give rise to the mature heart. AAO:0010411 EFO:0003526 @@ -48465,14 +48755,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac heart tube heart tube - + - + ZFA-modified @@ -49187,7 +49477,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. AAO:0011129 TAO:0001890 @@ -49201,14 +49491,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac skeletal element skeletal element - + - + VSAO @@ -49236,7 +49526,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -49269,14 +49559,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac articular system articular system - + - + FMA @@ -49974,7 +50264,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -49990,14 +50280,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac trunk mesenchyme trunk mesenchyme - + - + EHDAA2 @@ -50115,7 +50405,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. EHDAA2:0001512 EHDAA:424 @@ -50133,14 +50423,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac primitive heart tube primitive heart tube - + - + ZFA @@ -50300,7 +50590,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -50310,7 +50600,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac developing mesenchymal condensation developing mesenchymal condensation - + @@ -50329,7 +50619,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + AEO-modified-relation @@ -50425,7 +50715,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB EHDAA2:0001278 @@ -50439,7 +50729,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac notochordal plate notochordal plate - + @@ -50452,7 +50742,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + EHDAA2 @@ -50481,7 +50771,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -50498,14 +50788,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac notochordal process notochordal process - + - + EHDAA2 @@ -51379,7 +51669,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -51405,7 +51695,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac presumptive paraxial mesoderm presumptive paraxial mesoderm - + @@ -51421,7 +51711,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + https://github.com/obophenotype/uberon/issues/1277 @@ -51498,7 +51788,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -51506,7 +51796,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac dense mesenchyme tissue dense mesenchyme tissue - + @@ -51519,7 +51809,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + AEO @@ -51585,7 +51875,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -51605,14 +51895,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac layer of synovial tissue layer of synovial tissue - + - + BTO @@ -51886,7 +52176,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -51903,14 +52193,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac vascular system vascular system - + - + MA @@ -51940,7 +52230,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -51956,14 +52246,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac entire embryonic mesenchyme entire embryonic mesenchyme - + - + EHDAA2 @@ -52019,7 +52309,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme @@ -52027,14 +52317,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac trunk paraxial mesoderm trunk paraxial mesoderm - + - + EHDAA2 @@ -52129,7 +52419,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -52139,14 +52429,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac anterior lateral plate mesoderm anterior lateral plate mesoderm - + - + ZFA @@ -52286,7 +52576,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -52305,14 +52595,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac UBERON:0010210 blood clot - + - + BTO @@ -52435,7 +52725,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -52445,14 +52735,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac microcirculatory vessel microcirculatory vessel - + - + ZFA @@ -52477,8 +52767,8 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. FMA:23879 SCTID:129140006 @@ -52490,11 +52780,11 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac subdivision of skeleton subdivision of skeleton - + - + @@ -52507,13 +52797,13 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + UBERONREF:0000003 - + VSAO @@ -52607,7 +52897,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -52618,7 +52908,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton postcranial axial skeletal system - + @@ -52631,7 +52921,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + cjm @@ -53027,7 +53317,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -53047,7 +53337,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac UBERON:0012429 hematopoietic tissue - + @@ -53060,7 +53350,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + defitional @@ -53733,7 +54023,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + @@ -53756,7 +54046,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac entire extraembryonic component entire extraembryonic component - + @@ -53769,7 +54059,7 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + AEO @@ -54310,14 +54600,14 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac - + - + definitional - + @@ -54613,6 +54903,40 @@ Furthermore, the bone marrow hematopoietic cells have a unique ability to replac + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/subsets/blood_and_immune_upper_slim.tsv b/subsets/blood_and_immune_upper_slim.tsv index 9948fe8e3..0f2310d62 100644 --- a/subsets/blood_and_immune_upper_slim.tsv +++ b/subsets/blood_and_immune_upper_slim.tsv @@ -598,9 +598,9 @@ http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0098542 defense response to other organism http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer -http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen +http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers -http://purl.obolibrary.org/obo/GO_0098645 collagen network +http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098657 import into cell http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0098794 postsynapse @@ -658,6 +658,7 @@ http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota +http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda @@ -711,6 +712,7 @@ http://purl.obolibrary.org/obo/PATO_0001407 mononucleate http://purl.obolibrary.org/obo/PATO_0001501 immature http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0001579 contractility +http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0001873 cylindrical @@ -729,6 +731,7 @@ http://purl.obolibrary.org/obo/PATO_0002045 dendritic http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance +http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002318 superelliptic diff --git a/subsets/eye_upper_slim.json b/subsets/eye_upper_slim.json index afa4e853c..bd1f83f03 100644 --- a/subsets/eye_upper_slim.json +++ b/subsets/eye_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2025-12-17" + "val" : "2026-03-17" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2025-12-17/subsets/eye_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2026-03-17/subsets/eye_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -40,7 +40,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { - "val" : "FBbt:00007002" + "val" : "FBbt:00007002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:68646" }, { @@ -56,7 +62,13 @@ }, { "val" : "XAO:0003012" }, { - "val" : "ZFA:0009000" + "val" : "ZFA:0009000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -93,7 +105,13 @@ "val" : "neuronal receptor cell (sensu Animalia)" } ], "xrefs" : [ { - "val" : "ZFA:0009001" + "val" : "ZFA:0009001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -111,7 +129,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009002" + "val" : "ZFA:0009002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -129,7 +153,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007091" + "val" : "ZFA:0007091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -147,14 +177,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009010" + "val" : "ZFA:0009010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Glioblasts are primarily found in the central nervous system and are an integral part of the developing and mature brain tissue. They are primitive progenitor cells with the ability to self-renew and can differentiate into neuroglia, including astrocytes and oligodendrocytes, two primary cells involved in neurotransmission and protection of brain tissue. \nWhen glioblast multiplication is dysregulated, it can lead to harmful manifestations, most notably in the form of an aggressive brain tumor known as Glioblastoma multiforme, one of the most malignant types of neural cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000030" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000030", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "glioblast on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -176,7 +218,13 @@ }, { "val" : "FMA:70563" }, { - "val" : "ZFA:0009011" + "val" : "ZFA:0009011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -192,10 +240,9 @@ "val" : "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, - "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { - "pred" : "hasExactSynonym", + "pred" : "hasNarrowSynonym", "val" : "animal stem cell" } ], "xrefs" : [ { @@ -203,7 +250,13 @@ }, { "val" : "FMA:63368" }, { - "val" : "ZFA:0005957" + "val" : "ZFA:0005957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -213,7 +266,13 @@ "val" : "Stem cells are a unique type of cell that has the remarkable ability to divide and develop into many different types of cells in the body. These cells are undifferentiated, meaning they haven't yet developed into a specific cell type, and they can renew themselves through cell division. As a result, stem cells have the potential to replace damaged or diseased cells in the body, making them a valuable tool in medicine and research.\nThere are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos and can develop into any type of cell in the body. Adult stem cells, on the other hand, are found in various tissues and organs throughout the body and can only develop into certain types of cells.\nStem cells have numerous potential applications in medicine, including the treatment of various diseases and the repair of damaged tissues. For example, they could be used to replace damaged heart tissue after a heart attack or to repair spinal cord injuries. Stem cells also have potential uses in drug development and disease research, as they can be used to model diseases and test potential therapies in vitro.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stem cell" @@ -255,7 +314,13 @@ }, { "val" : "VHOG:0001485" }, { - "val" : "ZFA:0009014" + "val" : "ZFA:0009014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -265,7 +330,13 @@ "val" : "Hematopoietic stem cells (HSCs) are multipotent cells, capable of differentiating into a wide variety of specialized blood cells. During embryonic development hematopoietic stem cells emerge from the hemogenic endothelium, a specialized subset of endothelial cells with hematopoietic potential. HSCs can be found in several organs, in particular in bone marrow, as well as peripheral blood and umbilical cord blood.\nThese stem cells have a distinctive ability to self-renew, and to differentiate into all lymphoid and myeloid cell types that together form the blood and immune systems including erythrocytes (red blood cells), leukocytes (white blood cells), and platelets. Their primary function is to ensure the continuous replenishment of the blood and immune system throughout an individual's lifespan.\nIn response to various signals, hematopoietic stem cells can either remain dormant or actively divide and differentiate. Under normal conditions, the majority of these stem cells exist in a quiescent (inactive) state, making them somewhat resistant to chemotherapy or radiation therapy in the treatment of various diseases such as leukemia. However, when the body encounters stress such as infection, bleeding, or disease, hematopoietic stem cells can rapidly become active in order to replenish the affected cells and maintain homeostasis.\nFurthermore, hematopoietic stem cells are extremely important in the field of regenerative medicine and transplantation. Regarded as lifesaving in the field of oncology, they are often extracted, purified, and reinfused back into the same (autologous transplantation) or different (allogeneic transplantation) individuals to reestablish a healthy, functioning hematopoietic and immune system after high-dose chemotherapy or to replace dysfunctional bone marrow. Understanding and manipulating the behavior of these stem cells has immense potential in treating various blood disorders, autoimmune diseases, and cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "hematopoietic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "hematopoietic stem cell" @@ -305,14 +376,26 @@ "xrefs" : [ { "val" : "BTO:0004911" }, { - "val" : "ZFA:0009015" + "val" : "ZFA:0009015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Erythroid progenitor cells play a key role in the hematopoietic system, specifically in the process of erythropoiesis – the production of red blood cells (erythrocytes). Found within the bone marrow, these cells are dedicated precursors to erythrocytes, and ensue in the hematopoietic lineage from multipotent progenitors. They represent a transitional cell type that bridges the gap between the early-stage erythroid precursors and the maturing red blood cell population.\nThe earliest committed erythroid progenitor cell is thought to be the burst-forming unit-erythroid (BFU-E) cell, which after several cell divisions gives rise to another erythroid progenitor, the colony-forming unit-erythroid (CFU-E) cell. \nErythroid progenitor cells are primarily responsible for responding to the demand for new red blood cells during conditions of physiological stress like infection, blood loss, or illness. This responsive behavior is regulated by a glycoprotein hormone known as erythropoietin, which is produced by the kidneys. Erythropoietin interacts with the receptors on the erythroid progenitor cells, prompting them to proliferate and differentiate into erythroblasts. The erythroblasts then further mature, eventually producing new, functional red cells.\nThe role of erythroid progenitor cells extends beyond their main function of erythrocyte production, as they also participate in maintaining the balance of iron in the body. Upon erythroid differentiation, they increase their uptake of transferrin-bound iron for hemoglobin synthesis, a vital component of red blood cells which allows them to transport oxygen. A deficiency or excess of erythroid progenitor cells can lead to extensive health issues such as anemia or polycythemia respectively, emphasizing their crucial role in human health.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythroid progenitor cell" @@ -344,7 +427,13 @@ "xrefs" : [ { "val" : "FMA:84789" }, { - "val" : "ZFA:0009020" + "val" : "ZFA:0009020", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -400,7 +489,13 @@ "xrefs" : [ { "val" : "BTO:0004730" }, { - "val" : "ZFA:0009021" + "val" : "ZFA:0009021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -410,7 +505,13 @@ "val" : "The common myeloid progenitor (CMP) is a multipotent cell that serves as a crucial intermediary within the overall framework of hematopoietic cell differentiation, which is the process of blood cell production. This part of the hematopoiesis process leads to the formation of myeloid lineage cells, which includes granulocytes (neutrophils, eosinophils, and basophils), monocytes, erythrocytes (red blood cells), and megakaryocytes (platelet-forming cells). \nThe primary function of common myeloid progenitors is differentiation and proliferation into various types of mature blood cells, thereby providing a critical contribution to maintaining homeostasis within the body's immune and circulatory systems. Single-cell analyses have shown that the CMP cell population is heterogeneous with at least two distinct subpopulations, characterized by different cell surface markers and likely already committed to downstream differentiation into either the granulocyte/macrophage lineage or the megakaryocyte/erythrocyte lineage-restricted progenitor. \nThe destiny of a CMP is influenced by numerous cytokines and growth factors in its environment that promote differentiation along specific lineages. For example, IL-3 and GM-CSF stimulate the production of eosinophils, which are essential for the body’s defense against allergens and help fight fungal and parasitic infections. \nBy being able to differentiate into a wide range of different immune cells, common myeloid progenitors play a crucial role in the body's ability to respond to injuries, infections, and other physiological challenges.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "common myeloid progenitor on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "common myeloid progenitor" @@ -450,7 +551,13 @@ "val" : "megakaryocyte/erythroid progenitor cell" } ], "xrefs" : [ { - "val" : "ZFA:0009022" + "val" : "ZFA:0009022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -460,7 +567,13 @@ "val" : "The megakaryocyte-erythroid progenitor (MEP) cell belongs to the multipotent hematopoietic progenitor cells, which can give rise to multiple different cell types. They are found in the bone marrow, the primary organ where new blood cells are generated. MEPs are specially programmed to develop into two distinct blood cell lineages, namely megakaryocytes, which go on to produce platelets for blood clotting, and the erythroid lineage which consists of red blood cells responsible for oxygen transport in the body.\nThe MEP cells are the result of a decision-making process within the hematopoietic stem cell population. Hematopoietic stem cell can differentiate into multiple types of progenitor cells, including myeloid progenitor cells. A further subdivision within this myeloid lineage generates the MEP cells. Therefore, these megakaryocyte-erythroid progenitors represent a key juncture between hematopoietic stem cells and mature blood cell types in the myeloid lineage.\nMegakaryocyte-erythroid progenitor cells play a crucial role in the homeostasis of some of the most crucial constituents of blood. The megakaryocytes produced from these bipotent progenitor cells contribute to hemostasis by producing platelets - small anucleated fragments that are pivotal for blood clotting and preventing bleeding. Similarly, the erythroid lineage from MEP cells gives rise to erythrocytes, which harbor hemoglobin, the molecule that transports oxygen from lungs to every nook and corner of the body. An imbalance or malfunction in MEP function thus can significantly impact human health, leading to diseases like thrombocytopenia or anemia.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte-erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "megakaryocyte-erythroid progenitor cell" @@ -485,7 +598,13 @@ }, { "val" : "MESH:D039901" }, { - "val" : "ZFA:0009024" + "val" : "ZFA:0009024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -507,13 +626,25 @@ }, { "val" : "CALOHA:TS-0650" }, { - "val" : "FBbt:00005083" + "val" : "FBbt:00005083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:70335" }, { "val" : "VHOG:0001529" }, { - "val" : "ZFA:0009025" + "val" : "ZFA:0009025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -542,7 +673,13 @@ }, { "val" : "VHOG:0001482" }, { - "val" : "ZFA:0009026" + "val" : "ZFA:0009026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -573,13 +710,25 @@ }, { "val" : "CARO:0000077" }, { - "val" : "FBbt:00000124" + "val" : "FBbt:00000124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:66768" }, { "val" : "WBbt:0003672" }, { - "val" : "ZFA:0009034" + "val" : "ZFA:0009034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -603,7 +752,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009036" + "val" : "ZFA:0009036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -613,7 +768,13 @@ "val" : "Blood vessel endothelial cells, also known as vascular endothelial cells, form the delicate inner lining of the complex circulatory system, including arteries and veins. These cells form a single, continuous monolayer inside every blood vessel, acting as a crucial biomolecular barrier between the blood, and the rest of the body tissues. They perform various fundamental biological functions, ranging from maintenance of vessel integrity to blood clotting regulation. Additionally, they control the transportation of fluids, molecules, and blood particulate matter from and into the bloodstream.\nOne of the primary functions of blood vessel endothelial cells is to maintain vascular homeostasis - a stable environment within the blood vessels. They accomplish this through several methods: they control vasomotor tone, i.e. the degree of contraction and dilation of blood vessels, by secreting vasoactive substances such as nitric oxide and endothelin; mediate responses to inflammatory stimuli; and they also regulate angiogenesis, the process of new blood vessel formations. Blood vessel endothelial cells play a significant role in preventing blood clot formation by generating a slick, non-thrombogenic surface that disallows platelets or coagulant proteins from adhering to it.\nBlood vessel endothelial cells are sensitive to various stimuli, including shear stress caused by blood flow, and they can respond by altering their morphology, function, and gene expression. This ability to adapt enables blood vessels to remodel and ensure the adequate delivery of nutrients and oxygen to all tissues, regardless of physiological demand variations. Conversely, endothelial dysfunction, often associated with a reduction in the bioavailability of endothelium-derived nitric oxide, can lead to the development of pathological conditions such as atherosclerosis, hypertension, diabetes mellitus, and even aging-related diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "blood vessel endothelial cell" @@ -630,7 +791,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009038" + "val" : "ZFA:0009038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -645,13 +812,25 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "definition" : { + "val" : "An epithelial cell that has a flattened morphology." + }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" }, { - "val" : "ZFA:0009039" + "val" : "ZFA:0009039", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/date", + "val" : "2025-12-16T15:56:39Z" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "squamous epithelial cell" } ] @@ -674,7 +853,13 @@ "xrefs" : [ { "val" : "FMA:66773" }, { - "val" : "ZFA:0009040" + "val" : "ZFA:0009040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -684,7 +869,13 @@ "val" : "Mesothelial cells are crucial components of the mesothelium, a protective layer that lines the body's internal cavities, including pleural cavity (around the lungs), the pericardial cavity (around the heart), and the peritoneal cavity (within the abdomen). Derived from the embryonic mesoderm layer, these cells exhibit a squamous-like epithelial morphology, usually appearing as a single layer of flat, pavement-like cells in their healthy state.\nMesothelial cells play a vital role in various physiological processes, such as intraperitoneal immunity, fibrinolysis, tissue repair, and tumor suppression. Their primary function is to provide a slippery, non-adhesive and protective surface to reduce friction and eases the movements of the organs within the pleural, pericardial, and peritoneal cavities, and they participate in the transport and movement of fluid and various molecules across the so-called serosal cavities. \nThese cells have adaptive capabilities that facilitate their role in many pathological processes. In response to injury or inflammation, mesothelial cells can undergo morphological and functional changes, such as mesothelial-mesenchymal transitions, aiding in wound healing and tissue repair. Dysfunctions of mesothelial cells, however, can lead to serious health conditions, including adhesions, fibrosis, and malignancies such as peritoneal and pleural mesotheliomas.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -702,7 +893,13 @@ }, { "val" : "MESH:D001773" }, { - "val" : "ZFA:0009044" + "val" : "ZFA:0009044", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -737,13 +934,25 @@ "xrefs" : [ { "val" : "BTO:0003811" }, { - "val" : "FBbt:00005125" + "val" : "FBbt:00005125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67313" }, { "val" : "WBbt:0005113" }, { - "val" : "ZFA:0009051" + "val" : "ZFA:0009051", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -766,7 +975,13 @@ "xrefs" : [ { "val" : "BTO:0001037" }, { - "val" : "FBbt:00005124" + "val" : "FBbt:00005124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:84649" }, { @@ -774,7 +989,13 @@ }, { "val" : "WBbt:0005759" }, { - "val" : "ZFA:0009053" + "val" : "ZFA:0009053", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -806,7 +1027,13 @@ }, { "val" : "FMA:66772" }, { - "val" : "ZFA:0009065" + "val" : "ZFA:0009065", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -846,11 +1073,23 @@ }, { "val" : "CALOHA:TS-0415" }, { - "val" : "FBbt:00005144" + "val" : "FBbt:00005144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54536" }, { - "val" : "ZFA:0009073" + "val" : "ZFA:0009073", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -860,7 +1099,13 @@ "val" : "Glial cells, also known as neuroglia or simply glia, are non-neuronal cells in the central and peripheral nervous systems that provide support and protection for neurons. They constitute approximately half of the total cells in the human brain and more than half in other parts of the nervous system. Glial cells perform several key functions including, but not limited to, maintaining homeostasis, forming the myelin sheath around the neuron axons, and providing support and nutrition to neurons.\nThese different functions are performed by various glial cell types, including astrocytes, oligodendrocytes, microglia and other specialized types. Astrocytes, for example, are the most abundant glial cells and provide metabolic and nutrient support to neurons, help regulate the extracellular ion and neurotransmitter levels, and play a role in the formation and maintenance of the blood-brain barrier, contributing to the overall homeostasis and functioning of the nervous system. Additionally, astrocytes are involved in synaptic communication and participate in processes such as synaptogenesis and synaptic pruning.\nOligodendrocytes in the central nervous system function to insulate neurons by producing a fatty substance known as myelin. The myelin sheath enhances the speed and efficiency of nerve impulse conduction along the axons. \nMicroglia, the immune cells of the central nervous system, protect neurons from pathogens and clear away dead neurons through phagocytosis, a process also known as cellular eating. They also contribute to the regulation of inflammation in response to signals of tissue damage or infection in the central nervous system by releasing cytokines and other signaling molecules that modulate the immune response.\nDespite their overarching function in the support and protection of neurons, glial cells have also been shown to play significant roles in the pathophysiology of many psychiatric and neurodegenerative diseases, such as Alzheimer’s, Parkinson’s Disease and multiple sclerosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000125" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "glial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "glial cell" @@ -892,7 +1137,13 @@ }, { "val" : "FMA:54538" }, { - "val" : "ZFA:0009074" + "val" : "ZFA:0009074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -917,7 +1168,13 @@ }, { "val" : "FMA:54537" }, { - "val" : "ZFA:0009075" + "val" : "ZFA:0009075", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -939,7 +1196,13 @@ }, { "val" : "FMA:70614" }, { - "val" : "ZFA:0009079" + "val" : "ZFA:0009079", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -949,7 +1212,13 @@ "val" : "Corneal endothelial cells are specialized cells located on the innermost layer of the cornea, known as the endothelium. The cornea is the clear outer layer of the eye that helps to transmit and focus light into the retina. The endothelium is crucial in maintaining corneal clarity by actively pumping water out of the corneal stroma, the thick, collagen-containing middle layer of the cornea, to prevent swelling and ensure transparency.\nCorneal endothelial cells are characterized by their unique hexagonal shape forming a mosaic, and they are highly metabolically active. Their primary function is to maintain corneal dehydration and thereby clarity through maintaining a barrier and an active 'pump-leak' mechanism, which regulates fluid and solute transport. This transport sustains the deturgescence (state of being non-swollen) of the corneal stroma, since stromal swelling can cause corneal opacification, hindering light transmission. Importantly, human corneal endothelial cells have limited regenerative capacity, so damage to them, through disease, aging, or surgical trauma may result in vision loss.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000132" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000132", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "corneal endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -967,7 +1236,13 @@ "val" : "neurectoderm cell" } ], "xrefs" : [ { - "val" : "ZFA:0009080" + "val" : "ZFA:0009080", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1039,14 +1314,26 @@ }, { "val" : "FMA:70546" }, { - "val" : "ZFA:0009081" + "val" : "ZFA:0009081", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. These cells originate mainly from the mesoderm of the embryo, which forms connective tissues, muscle, and the circulatory and urinary systems. However, in adults, MSCs are found in multiple tissues, including bone marrow, adipose tissue, the umbilical cord, and dental tissues. \nThe primary function of MSCs is to maintain and repair the tissues in which they are found. When damage occurs, the MSCs are able to migrate to the site of injury, where they aid in regenerating the damaged tissue by differentiating into the required cell type and by secreting growth factors that enhance tissue repair and reduce inflammation. Furthermore, MSCs can also act as immunomodulators, suppressing immune reactions and reducing inflammation, both locally and systemically.\nApart from their role in tissue maintenance and repair, MSCs are integral to the field of regenerative medicine and are being investigated for their therapeutic potential in various clinical settings. Owing to their multipotent nature, immunomodulatory activity, and the relative ease of isolation, these cells can be engineered and translated into therapies to treat a variety of diseases, including bone and cartilage defects, liver diseases, heart disorders, and autoimmune diseases, amongst others. They have also been used as vectors for anticancer agents and in cell and gene therapy applications.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val" : "https://github.com/obophenotype/cell-ontology/issues/474" @@ -1075,7 +1362,13 @@ "xrefs" : [ { "val" : "VHOG:0001678" }, { - "val" : "ZFA:0009090" + "val" : "ZFA:0009090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1107,7 +1400,13 @@ }, { "val" : "VHOG:0001679" }, { - "val" : "ZFA:0009091" + "val" : "ZFA:0009091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1117,7 +1416,13 @@ "val" : "Melanocytes are specialized cells prevalently found in the skin, but also present in the hair follicles, eyes, inner ear, bones, heart, and brain. Their primary function is the synthesis of melanin, a pigment responsible for coloration of skin, hair, and eyes. The presence and distribution of this pigment play a crucial role in the body's defense mechanism against harmful ultraviolet radiation.\nIn addition to melanin production, melanocytes also engage in a variety of other biological functions. They play a fundamental role in the immune response, owing to their ability to present antigens to T cells. Furthermore, they contribute to the maintenance of the skin's homeostasis by regulating processes such as extracellular matrix remodeling and cytokine production. A balance in melanocyte function is pivotal, as dysfunctions often result in dermatological disorders. For instance, the loss of melanocytes or reduction in their function may lead to hypopigmentation conditions such as vitiligo, whereas an abnormal increase could result in hyperpigmentation disorders or melanoma, a dangerous type of skin cancer.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000148" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000148", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "melanocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1186,7 +1491,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1201,15 +1506,30 @@ }, { "val" : "CALOHA:TS-2032" }, { - "val" : "FBbt:00005074" + "val" : "FBbt:00005074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67328" }, { "val" : "WBbt:0003675" }, { - "val" : "ZFA:0009114" + "val" : "ZFA:0009114", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle cell" }, { @@ -1249,7 +1569,13 @@ }, { "val" : "FMA:14072" }, { - "val" : "ZFA:0009118" + "val" : "ZFA:0009118", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1259,7 +1585,13 @@ "val" : "Smooth muscle cells are a specialized type of muscle cells that are primarily found within the walls of hollow organs such as the intestine, stomach, bladder, uterus, and blood vessels. These cells are an essential component of the autonomic nervous system controling involuntary movements within the body.\nSmooth muscle cells play a vital role in many physiological processes due to their unique functionality. They can contract and relax in a slow, sustained, and controlled manner to help modulate the size and shape of the lumens of the organs they surround. For example, in the digestive system, coordinated contraction and relaxation of smooth muscle cells propels food along the gastrointestinal tract - a process known as peristalsis. In the blood vessels, the smooth muscle cells, by contracting or relaxing, either constrict or dilate the vessels, which in turn, help regulate blood flow and pressure.\nOn a cellular level, smooth muscle cells possess a single, centrally located nucleus and contain an arranged network of actin and myosin filaments, which are the proteins responsible for muscle contraction. Unlike their counterparts in skeletal or cardiac muscles, these cells lack specific contact points for these filaments, hence the lack of visible striations. Furthermore, the contraction of smooth muscle cells is regulated by hormones and neurotransmitters, such as acetylcholine and norepinephrine, adding an additional layer of complex regulation to these highly specialized cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000192" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000192", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "smooth muscle cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "smooth muscle cell" @@ -1301,18 +1633,36 @@ }, { "val" : "CALOHA:TS-0868" }, { - "val" : "FBbt:00004211" + "val" : "FBbt:00004211", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86740" }, { - "val" : "ZFA:0009127" + "val" : "ZFA:0009127", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Photoreceptor cells are specialized types of neurons found in the retina, responsible for the vital task of converting light into signals that can stimulate a visual response. These cells are called photoreceptor cells because they are light-sensitive, enabling vision in conditions ranging from extremely dim to very bright light. There are two main types of photoreceptor cells in the human eye: rods, which are highly sensitive to light and allow for vision in low-light conditions, and cones, which are responsible for color vision and function best in bright light.\nThe photoreceptor cells function by absorbing light rays and converting them into electrical signals. These signals are then sent to the brain via the optic nerve and are interpreted as visual images. This process begins when the photopigment (a light-sensitive compound) found in photoreceptor cells absorbs light, which triggers a chemical reaction. This reaction leads to changes in the photopigment's configuration and, consequently, alters its electrical properties. This change initiates a signal that is transmitted through the cell and onwards to connecting neurons.\nFurthermore, photoreceptor cells exhibit a unique and highly specialized structure that reflects their function. Rods, named because of their elongated, rod-shaped structure, consist of an outer segment filled with disks containing rhodopsin, the photopigment responsible for detecting light. Cones, on the other hand, are more conical and have three different types of photopigments, each one sensitive to a different range of wavelengths, allowing for the perception of color. Given the importance of photoreceptor cells in vision, damage or degeneration to these cells can lead to vision impairment or blindness, highlighting their key role in visual perception.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000210" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000210", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "photoreceptor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "photoreceptor cell" @@ -1332,7 +1682,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009128" + "val" : "ZFA:0009128", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1355,7 +1711,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-0995" }, { - "val" : "ZFA:0009131" + "val" : "ZFA:0009131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1369,7 +1731,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009136" + "val" : "ZFA:0009136", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1393,7 +1761,13 @@ "xrefs" : [ { "val" : "FMA:72549" }, { - "val" : "ZFA:0009137" + "val" : "ZFA:0009137", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1420,14 +1794,26 @@ "xrefs" : [ { "val" : "FMA:72554" }, { - "val" : "ZFA:0009138" + "val" : "ZFA:0009138", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesodermal cells are pluripotent and the most abundant in the human body. They contribute to the development of several structures such as the skeletal muscles, bones, heart and blood vessels, kidneys, gonads, connective tissues, and certain layers of the skin. Hence, the mesoderm is often regarded as an active and diverse layer due to its role in forming many bodily structures. \nIn embryonic development, these cells are instrumental, contributing to the body's structures through a carefully coordinated sequence of morphogenetic movements. This process forms the complex multicellular architecture of tissues and organs from a simple ball of cells. Without the function of mesodermal cells, the body's integral structures and systems would cease to form correctly, leading to developmental disorders such as axial mesodermal dysplasia complex\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesodermal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesodermal cell" @@ -1450,7 +1836,13 @@ "xrefs" : [ { "val" : "FMA:72555" }, { - "val" : "ZFA:0009139" + "val" : "ZFA:0009139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1489,7 +1881,13 @@ "val" : "Erythrocytes, also known as red blood cells, are a type of specialized cell that make up the largest percentage of cells in the human body. Erythrocytes are biconcave in shape and lack nuclei and organelles, allowing them to carry oxygen and carbon dioxide through the bloodstream more efficiently. The main function of erythrocytes is to transport oxygen from the lungs to the body's tissues and organs, and to transport carbon dioxide from the body's tissues to the lungs, where it can be exhaled out of the body. Hemoglobin, a protein located inside erythrocytes, is responsible for binding to oxygen. \nErythrocytes are produced in the bone marrow and have a lifespan of approximately 120 days before they are broken down and recycled by the body. Erythrocytes are regulated by the hormone erythropoietin, which is produced by the kidneys and liver in response to low oxygen levels in the body, thereby stimulating erythrocyte production .\nIn addition to their role in oxygen transport, erythrocytes also play a key role in regulating the body's pH levels. Without erythrocytes, oxygen would not be able to be transported efficiently throughout the body and tissues would not receive the necessary oxygen to function properly. Overall, erythrocytes are essential for maintaining the health and homeostasis of the body.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythrocyte on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythrocyte" @@ -1524,7 +1922,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009154" + "val" : "ZFA:0009154", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1534,7 +1938,13 @@ "val" : "Eye photoreceptor cells, also commonly known as photoreceptors, are specialized types of cells found in the retina, the light-sensitive layer at the back of the eye. They are integral to the complex process of vision, as they are directly involved in converting light into electrical signals. This process is known as phototransduction. There are two primary classes of photoreceptor cells; rods, which function mainly in dim light and provide black-and-white vision, and cones, which function in brighter light and allow for the perception of color.\nRods and cones carry out their roles through sophisticated biochemical reactions. The main component of these reactions is a protein called opsin, which binds to a small molecule known as retinal. In the presence of light, retinal changes its shape, leading to a series of chemical reactions that result in changes to the cell’s electrical potential, thus creating an electrical signal that travels to the optic nerve. Rod cells possess only one kind of opsin, called rhodopsin, which only allows them to distinguish between light and dark. Conversely, cone cells have three types of opsins, allowing for the differentiation of various colors.\nThe spatial distribution of these cell types throughout the retina also contributes to their function. Rod cells are more numerous and are distributed more at the periphery of the retina, contributing to peripheral and night vision. On the other hand, cone cells are concentrated in the macula, a tiny central region in the retina, and with the highest density in the fovea, a small pit in the macula. This distribution of cones lies at the base of fine detail and color vision in the central visual field. In summary, eye photoreceptor cells carry out the primary function of transforming light into visual signals, a role that is crucial for the overall process of vision.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000287" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000287", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "eye photoreceptor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "eye photoreceptor cell" @@ -1597,7 +2007,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009164" + "val" : "ZFA:0009164", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1617,7 +2033,13 @@ "xrefs" : [ { "val" : "FMA:86667" }, { - "val" : "ZFA:0007086" + "val" : "ZFA:0007086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1635,7 +2057,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009166" + "val" : "ZFA:0009166", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1659,7 +2087,13 @@ "xrefs" : [ { "val" : "FMA:70564" }, { - "val" : "ZFA:0009169" + "val" : "ZFA:0009169", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1673,7 +2107,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009170" + "val" : "ZFA:0009170", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1687,7 +2127,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009174" + "val" : "ZFA:0009174", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1705,7 +2151,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009175" + "val" : "ZFA:0009175", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1760,7 +2212,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009190" + "val" : "ZFA:0009190", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1778,7 +2236,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009193" + "val" : "ZFA:0009193", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1800,7 +2264,13 @@ }, { "val" : "FMA:83624" }, { - "val" : "ZFA:0009226" + "val" : "ZFA:0009226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1810,7 +2280,13 @@ "val" : "Stromal cells constitute a significant portion of the structural cellular milieu (stroma) that supports the function of parenchymal (functional) cells within an organ. The stroma is the connective, supportive framework of biological tissues with various functions depending on the specific organ and cell type. Stromal cells, derived from the mesenchymal lineage, play crucial roles in creating, maintaining, and repairing the tissue microenvironment in virtually all mammalian organs, making these cells indispensable to biological function.\nAdditionally, stromal cells secrete growth factors, cytokines, and extracellular matrix (ECM) molecules to constitute an interactive cellular network and ensure an optimal environment for the functional cells. Beyond mere structural support, these cells are instrumental in wound healing, inflammation, and maintaining tissue integrity. They may also influence the behavior of other cell types through direct cell-cell interactions or paracrine signaling.\nClinically and in research, stromal cells often draw attention due to their interaction with tumors in the cancer microenvironment. Over the past years, the role of stromal cells as facilitators of tumor growth and metastasis has been recognized increasingly. They contribute to cancer progression not only by modulating the ECM but also through the secretion of various bioactive molecules and interacting with immune cells, thereby influencing the immunologic responses to tumors.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stromal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stromal cell" @@ -1837,14 +2313,26 @@ "xrefs" : [ { "val" : "FMA:84798" }, { - "val" : "ZFA:0009235" + "val" : "ZFA:0009235", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "A precursor to the smooth muscle cell, the smooth muscle myoblast, is integral to various body systems, including the cardiovascular, gastrointestinal, and respiratory systems. Smooth muscle myoblasts arise from the differentiation of mesenchymal stem cells, a process tightly regulated by specific genetic factors and environmental signals. Their role extends to myogenesis, particularly in the formation of muscular tissue, especially during embryonic development.\nSmooth muscle myoblasts possess distinctive cellular characteristics. In contrast to skeletal muscle myoblasts, they do not fuse to create multinucleated fibers. Instead, they differentiate into individual, uninucleated smooth muscle cells. This differentiation unfolds in two distinct phases: proliferation, marked by rapid division to increase cell numbers, and differentiation, involving structural and functional transformation into mature smooth muscle cells. This intricate process is intricately mediated by various signaling molecules and transcription factors.\nFunctionally, smooth muscle myoblasts and the mature muscle cells they generate play pivotal roles in various physiological processes. Smooth muscle cells orchestrate involuntary muscle responses and are integral to body systems that regulate blood flow, propel food along the digestive tract, and control airflow in the respiratory tract. These diverse functions underscore the significance of smooth muscle myoblasts in the body's growth, maintenance, and overall function.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000514" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000514", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "smooth muscle myoblast on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "smooth muscle myoblast" @@ -1867,7 +2355,13 @@ "xrefs" : [ { "val" : "FMA:87653" }, { - "val" : "ZFA:0009238" + "val" : "ZFA:0009238", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1884,7 +2378,13 @@ "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009241" + "val" : "ZFA:0009241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1907,7 +2407,13 @@ }, { "val" : "CALOHA:TS-0683" }, { - "val" : "FBbt:00005106" + "val" : "FBbt:00005106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54527" }, { @@ -1915,7 +2421,13 @@ }, { "val" : "WBbt:0003679" }, { - "val" : "ZFA:0009248" + "val" : "ZFA:0009248", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1944,7 +2456,13 @@ }, { "val" : "FMA:83377" }, { - "val" : "ZFA:0009249" + "val" : "ZFA:0009249", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -2003,7 +2521,13 @@ "xrefs" : [ { "val" : "FMA:83505" }, { - "val" : "ZFA:0005236" + "val" : "ZFA:0005236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2048,7 +2572,13 @@ "xrefs" : [ { "val" : "FMA:83506" }, { - "val" : "ZFA:0005241" + "val" : "ZFA:0005241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2189,7 +2719,13 @@ "val" : "A megakaryocyte is a large, unique, and complex cell type found primarily in the bone marrow, the spongy, semi-solid tissue located in the medullary cavities of certain bones. The term ‘megakaryocyte’ is derived from the Greek 'mega', meaning great, and 'karyon', referring to the nucleus. Megakaryocytes are characterized by their large size, typically with a diameter of 50-100 µm in humans, and the presence of a multilobulated nucleus; they are the largest hematopoietic cells in the bone marrow but also the rarest cells. \nThe primary function of a megakaryocyte is the production of platelets, also known as thrombocytes. Platelets are small, anucleate cell fragments that play a crucial role in the process of hemostasis, the arrest of blood loss from a damaged blood vessel. The process begins when the megakaryocyte extends long, branching processes called proplatelets, into the sinusoidal blood vessels present in the bone marrow. These proplatelets then fragment into the discoid structures recognized as platelets. Each megakaryocyte can produce thousands of platelets during its lifespan. \nApart from platelet production, megakaryocytes are involved in several other functions. They express immune-sensing receptors such as Fc-γ receptor and Toll-like receptors and produce factors such as platelet factor 4 and platelet-derived growth factor that can stimulate the immune system. Also, in certain pathological conditions, megakaryocytes release TGF-β and PDGF and contribute to bone marrow fibrosis, a condition characterized by excessive accumulation of fibrous tissue in the bone marrow leading to anemia. Recent studies have also highlighted the role of megakaryocytes in regulating hematopoiesis, the process of blood cell production. They can influence the bone marrow microenvironment and control the behavior of hematopoietic stem cells, the progenitors of all types of blood cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2209,7 +2745,13 @@ }, { "val" : "MESH:D012156" }, { - "val" : "ZFA:0009252" + "val" : "ZFA:0009252", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2245,7 +2787,13 @@ }, { "val" : "FMA:67766" }, { - "val" : "ZFA:0009255" + "val" : "ZFA:0009255", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2271,7 +2819,13 @@ "val" : "chondroplast" } ], "xrefs" : [ { - "val" : "ZFA:0009258" + "val" : "ZFA:0009258", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2300,7 +2854,13 @@ }, { "val" : "FMA:67748" }, { - "val" : "ZFA:0009262" + "val" : "ZFA:0009262", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2310,7 +2870,13 @@ "val" : "Retinal cone cells, or simply cone cells, are one out of the two types of photoreceptor cells in the retina, the other being retinal rod cells. They function by converting light into signals that can lead to a visual perception. These cells are less sensitive to light compared to rod cells, but they play a crucial role in our vision system for their ability to perceive color and provide sharp visual acuity. They are responsible for our daylight and color vision, enabling an individual to perceive fine detail and rapid changes in light levels.\nCone cells are specialized and named based on the absorption spectra of the visual pigments they contain, giving rise to three types of cone cells: short-wavelength S-cones (blue cones), middle-wavelength M-cones (green cones), and long-wavelength L-cones (red cones). The distribution of these cones across the retina differs, with greater densities at the central fovea region, contributing to why our central vision is so sharp and color-detailed compared to peripheral vision.\nThe outer segments of retinal cone cells house the photopigments that absorb light and initiate the process of phototransduction, a biochemical event by which the light signal is transformed into an electrical signal. When a cone cell is stimulated by light, an electrochemical reaction triggers nerve impulses, which are then transmitted to the brain by the optic nerve. There, these impulses are processed into the images that we see. Each type of cone responds to different wavelengths of light, enabling us to perceive a spectrum of color. By working in conjunction with rod cells, which are adapted for low-light vision scenarios, the cone cells provide us with a comprehensive and adaptable vision system.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000573" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000573", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal cone cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "retinal cone cell" @@ -2338,7 +2904,13 @@ }, { "val" : "FMA:70551" }, { - "val" : "ZFA:0009264" + "val" : "ZFA:0009264", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2348,7 +2920,13 @@ "val" : "Corneal epithelial cells are a specialized cell type that form the outermost layer of the cornea, the transparent dome-shaped tissue that covers the front of the eye. The corneal epithelium is 5-7 cells thick and is comprised of inner basal cells, middle wing cells and superficial squamous cells. \nThe corneal epithelium plays a crucial role in the maintenance of corneal transparency, protection against external insults, and the refractive power of the cornea. This cell type is responsible for the formation of tight junctions, desmosomes, and hemidesmosomes, which provide structural support to the corneal epithelium and prevent the infiltration of foreign particles and microorganisms. \nCorneal epithelial cells also have a unique and highly organized cytoskeleton that confers mechanical integrity and limits the penetration of foreign substances. Additionally, corneal epithelial cells secrete a variety of proteins and lipids that help to maintain the hydration and clarity of the cornea. These include mucins, which form a lubricating layer that facilitates blinking and limits dryness, and crystallins, which appear to protect against UV- and oxidative stress-induced apoptosis.\nDysfunction of corneal epithelial cells due to infections, inflammation, or injury can lead to corneal opacity, scarring, and impaired vision.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000575" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "corneal epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2373,7 +2951,13 @@ }, { "val" : "FMA:67747" }, { - "val" : "ZFA:0009275" + "val" : "ZFA:0009275", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2383,7 +2967,13 @@ "val" : "Retinal rod cells, often referred to simply as \"rod cells”, are a specialized type of photoreceptor cells found in the retina. Their primary function is to detect and convert light into electrochemical signals, which are then transmitted to the brain via nerve impulses. Compared to other types of photoreceptor cells, namely retinal cone cells, rod cells are more sensitive to light, and thus play a crucial role in night and peripheral vision.\nRod cells are named for their long, cylindrical shape, which is distinct from the cone-like shape of retinal cone cells. The structure of a rod cell is complex, with different sections responsible for various aspects of its function. The outer segment contains densely packed, light-sensitive membrane discs filled with a pigment called rhodopsin. When light hits rhodopsin, it prompts a chemical reaction that leads to the generation of electrochemical signals. These signals are processed in the cell's inner segment, which contains the cell's primary organelles, including the nucleus and mitochondria, and transmitted through the cell's synaptic terminal to the secondary neurons in the retina.\nRod cells are distributed across the majority of the retina, with the highest density found in the peripheral edges. This distribution, coupled with their high sensitivity to light, explains why rod cells contribute significantly to peripheral and low-light vision. However, they do not pick up color and have low spatial acuity, which means that while rod cells can detect the presence of light and movement, the finer details and colors of an image are processed mainly by cone cells. Together, rod cells and cone cells work in concert to enable a wide range of visual capabilities, making vision a complex and intricate biological process.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000604" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000604", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal rod cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "retinal rod cell" @@ -2414,7 +3004,13 @@ "xrefs" : [ { "val" : "BTO:0003064" }, { - "val" : "ZFA:0009280" + "val" : "ZFA:0009280", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2424,7 +3020,13 @@ "val" : "Mueller cells, also referred to as Műller glial cells, are a type of radial glial cell found specifically within the retina, the light-sensitive tissue lining the back interior surface of the eye. They derive their name from Heinrich Müller, who first described these cells in the mid-nineteenth century. These support cells contribute to maintaining the homeostasis and structural integrity of the retina. Mueller cells span the entire thickness of the retina, thus representing the only cell type that traverses all layers.\nMueller cells play a crucial role in maintaining the metabolic environment of retinal neurons and participating in the visual signal transduction. They have a unique organization and possess a wide range of processes, giving them direct contact with virtually every type of cell in the retina—including photoreceptors, bipolar cells, and ganglion cells. These cells actively uptake and recycle neurotransmitters, modulate chemical levels within the extracellular space, and are involved in potassium siphoning, thus supporting neuronal signaling. Due to these functions, they play a vital role in maintaining the physiological and functional stability of the retina.\nMoreover, Mueller cells are also responsible for maintaining the structural integrity of the retina. They serve as the retinal framework by providing structural support to neurons and blood vessels. They contribute to the formation and maintenance of the inner limiting membrane, comprising their end-feet at the vitreous surface. Additionally, they play an essential role during injury or disease, exhibiting reactive gliosis – a process where these cells undergo morphological and functional changes to aid in repair and protection from further damage. While their protective role is important, it's also worth noting that overactivation of Mueller cells may result in retinal scarring or degeneration, reinforcing their complex and delicate role in retinal health and disease.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000636" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000636", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Mueller cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2437,11 +3039,23 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "FBbt:00100291" + "val" : "FBbt:00100291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "WBbt:0006829" }, { - "val" : "ZFA:0009290" + "val" : "ZFA:0009290", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2462,14 +3076,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009291" + "val" : "ZFA:0009291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Muscle precursor cells, commonly referred to as myogenic progenitor cells or myoblasts, play a pivotal role in the intricate processes of muscle regeneration and development. As undifferentiated cells, they harbor the potential to evolve into distinct specialized cells, specifically the muscle cell or myocyte. Their crucial contribution lies in guiding the transformation of the mesodermal layer, one of the three primary germ cell layers in the early embryo, into fully developed skeletal muscle tissues during embryonic development.\nMuscle precursor cells are characterized by their proliferative capacity and rapid differentiation into mature myocytes. They fuse into myotubes, culminating in the formation of muscle fibers. Their responsiveness to signals such as insulin-like growth factors, transforming growth factor-β, and neural inputs enables precise control over their proliferation and differentiation. This regenerative capacity equips them with the ability to repair injured or damaged muscle tissue, a critical function in preserving muscle homeostasis and overall function. These cells also actively contribute to adaptive responses, such as muscle growth and strengthening, in reaction to factors like training or aging.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "muscle precursor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle precursor cell" @@ -2491,7 +3117,13 @@ "val" : "forebrain radial glial cell" } ], "xrefs" : [ { - "val" : "ZFA:0009292" + "val" : "ZFA:0009292", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2538,14 +3170,26 @@ }, { "val" : "MESH:D053687" }, { - "val" : "ZFA:0009307" + "val" : "ZFA:0009307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Somatic stem cells, also known as adult stem cells, are undifferentiated cells found throughout the body post-embryonic development. They reside in specialized niches within tissues such as the bone marrow, brain, muscles, skin, and liver. Fundamentally, these cells possess the ability to self-renew, maintaining their numbers, and to generate differentiated cells that replace dying cells and repair damaged tissues. \nThe potency of somatic stem cells varies based on their tissue of origin. For instance, hematopoietic stem cells in the bone marrow exhibit multipotency, giving rise to all blood cell types. Conversely, muscle stem cells display unipotency, generating only muscle cells.\nSomatic stem cells respond to environmental signals that regulate their quiescence, activation, and differentiation states. In response to tissue injury, they proliferate and differentiate into specific mature cell types to replace lost or damaged cells. Intricate mechanisms ensure a delicate balance between self-renewal and differentiation, guiding tissue maintenance and repair without risking aberrant cell proliferation leading to tumor formation.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "somatic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somatic stem cell" @@ -2585,7 +3229,13 @@ }, { "val" : "MESH:D012165" }, { - "val" : "ZFA:0009310" + "val" : "ZFA:0009310", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2595,7 +3245,13 @@ "val" : "Retinal ganglion cells (RGCs) are a type of neuron located near the inner surface of the retina, playing a critical role in the visual pathway. There are approximately 1 million RGCs in a typical human eye, each receiving inputs from multiple photoreceptor cells. As the only neurons in the retina that send information to the brain, they are the final output neurons of the vertebrate retina, and their axons constitute the majority of fibers in the optic nerve. \nThe primary function of RGCs is to receive visual information from photoreceptors via intermediary bipolar and amacrine cells, process it, and transmit it to the brain through their axons. The information that RGCs relay encompasses various aspects of the visual field, including color, contrast, brightness, and motion. A diverse population of RGCs, up to 30 distinct subtypes, each contributes to a specific aspect of vision, such as object motion, edge detection, or color contrast, illustrating the complexity of visual data processing that occurs already at the retinal level.\nRGCs also play a role in the regulation of circadian rhythms and the pupillary light reflex. Some RGCs contain the photopigment melanopsin and respond directly to light, separately from the retinal rod and cone cells found in the outer retina. These photosensitive RGCs are primarily involved in subconscious vision, particularly the regulation of circadian rhythms and the pupillary light reflex in response to changes in ambient light intensity. Hence, RGCs serve a highly specialized and diverse role in transmitting visual information and regulating light-dependent responses, view modalities, and key physiological processes.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000740" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000740", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal ganglion cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "retinal ganglion cell" @@ -2628,7 +3284,13 @@ "xrefs" : [ { "val" : "BTO:0004120" }, { - "val" : "ZFA:0009315" + "val" : "ZFA:0009315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2638,7 +3300,13 @@ "val" : "Retina horizontal cells are a specialized type of neuron found in the inner nuclear layer of the retina. They play a crucial role in the visual system by integrating and regulating the input from multiple photoreceptor cells, which sense and respond to light. Retina horizontal cells are so named due to their characteristic flat horizontal orientation, with their dendrites and axons coursing laterally in a plane parallel to the retinal surface.\nRetina horizontal cells are synaptically connected with photoreceptor cells (i.e., cones and rods) and bipolar cells. Their primary function is to facilitate the process of lateral inhibition, where an excited neuron reduces the activity of its neighbors. This capability is central to the phenomenon of \"contrast enhancement\" in visual perception, where the borders between light and dark areas are accentuated to better resolve images. Retina horizontal cells receive inputs from these neighboring photoreceptor cells and transmit their inhibitory output to not only photoreceptor cells but also bipolar cells, fine-tuning the responsiveness to changes in light intensity and differences in wavelengths.\nMoreover, retina horizontal cells play a substantial role in adaptation of retinal response to different light levels. In bright light conditions, they aid the reduction of the overall response to light stimuli, thus aiding in the prevention of photoreceptor saturation. These neurons are adept at adjusting the gain and thus the dynamic range of photoreceptors supporting the vision process under variable lighting conditions - from dim moonlight to bright sunshine. Therefore, retina horizontal cells contribute considerably to the adaptability, sharpness, and detail perception of our visual system.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000745" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000745", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retina horizontal cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2668,7 +3336,13 @@ "xrefs" : [ "geo:GSE137537" ] } ], "xrefs" : [ { - "val" : "ZFA:0009318" + "val" : "ZFA:0009318", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2678,7 +3352,22 @@ "val" : "The retinal bipolar neuron is an integral part of the eye, specifically located within the retina. They are secondary neurons in the visual pathway and primarily serve to transmit information from photoreceptor cells, which respond to light, to retinal ganglion cells, which carry the signal to the brain. As such, these cells play a pivotal role in our ability to interpret and perceive visual information.\nThe structure of retinal bipolar neurons is unique and significant to their function. They are termed \"bipolar\" due to their morphology, having two poles: a single dendrite on one end and an axon on the other. The dendrite end connects to photoreceptor cells (rods or cones), while the axon end synapses with retinal ganglion cells. In the center of the dendrite and axon lies the cell body, which houses the cell's nucleus and other vital organelles.\nAt the functional level, retinal bipolar neurons can be categorized into ON and OFF types based on their response to light. 'ON' bipolar cells are depolarized (electrical potential across the cell membrane decreases) under light conditions, thereby increasing their rate of neurotransmitter release onto the downstream ganglion cells. In contrast, 'OFF' bipolar cells are hyperpolarized (electrical potential increases) in light conditions, decreasing their rate of neurotransmitter release. This dual system allows for a fine-tuned response and the ability to perceive differences in light intensity and contrast, thus creating a nuanced and detailed visual world.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000748" + "val" : "https://celltype.info/project/544/dataset/1157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "reference transcriptomic data on Cell Annotation Platform" + } ] + } + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000748", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal bipolar neuron on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2698,7 +3387,13 @@ }, { "val" : "MESH:D022423" }, { - "val" : "ZFA:0009324" + "val" : "ZFA:0009324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2727,7 +3422,13 @@ }, { "val" : "FMA:83516" }, { - "val" : "ZFA:0009325" + "val" : "ZFA:0009325", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2760,7 +3461,13 @@ }, { "val" : "MESH:D004900" }, { - "val" : "ZFA:0005237" + "val" : "ZFA:0005237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2790,7 +3497,13 @@ }, { "val" : "CALOHA:TS-0448" }, { - "val" : "ZFA:0009354" + "val" : "ZFA:0009354", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2822,7 +3535,13 @@ }, { "val" : "FMA:70339" }, { - "val" : "ZFA:0009356" + "val" : "ZFA:0009356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2861,7 +3580,13 @@ }, { "val" : "FMA:83598" }, { - "val" : "ZFA:0005830" + "val" : "ZFA:0005830", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2924,7 +3649,13 @@ "xrefs" : [ { "val" : "FMA:69074" }, { - "val" : "ZFA:0009385" + "val" : "ZFA:0009385", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2954,7 +3685,13 @@ "xrefs" : [ { "val" : "FMA:69076" }, { - "val" : "ZFA:0009388" + "val" : "ZFA:0009388", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3000,7 +3737,13 @@ "val" : "2010-08-24T02:06:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "endothelial cell of vascular tree on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "endothelial cell of vascular tree" @@ -3105,7 +3848,13 @@ "val" : "2010-09-13T04:09:27Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002303" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002303", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "pigmented ciliary epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3145,7 +3894,13 @@ "val" : "2010-09-13T04:09:31Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002304" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002304", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "non-pigmented ciliary epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3191,7 +3946,13 @@ }, { "val" : "MESH:D003239" }, { - "val" : "ZFA:0009392" + "val" : "ZFA:0009392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3221,7 +3982,13 @@ }, { "val" : "WBbt:0007028" }, { - "val" : "ZFA:0007089" + "val" : "ZFA:0007089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3234,7 +4001,13 @@ "val" : "2010-09-15T03:39:21Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "embryonic cell (metazoa) on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "embryonic cell (metazoa)" @@ -3271,7 +4044,13 @@ "val" : "2010-09-22T01:57:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002363" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002363", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "keratocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3372,7 +4151,13 @@ "val" : "2011-03-06T03:28:27Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002585" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002585", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3385,6 +4170,12 @@ "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", + "pred" : "hasExactSynonym", + "val" : "RPE", + "xrefs" : [ "PMID:35835183" ] + } ], "xrefs" : [ { "val" : "BTO:0004910" }, { @@ -3404,7 +4195,13 @@ "val" : "2011-03-06T03:37:09Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002586" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002586", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "retinal pigment epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3440,7 +4237,13 @@ "comments" : [ "Is_a interneuron, part_of UBERON:0002240." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0000778" + "val" : "ZFA:0000778", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -3458,7 +4261,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007084" + "val" : "ZFA:0007084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -3512,7 +4321,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "FBbt:00005070" + "val" : "FBbt:00005070", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -3540,7 +4355,13 @@ "val" : "Mesenchymal cells are a type of undifferentiated cell that possess the ability to develop into a wide variety of other cells. These cells originate from the mesoderm during embryonic development, which gives rise to tissues such as muscles, the skeletal system, and connective and vascular structures. Mesenchymal cells primarily function as progenitor cells with exceptional renewal capabilities and are characterized by their ability to migrate, aiding in tissue repair and regeneration.\nMesenchymal cells play a critical role in the development and maintenance of various biological systems throughout the body due to their versatility and adaptability. They can differentiate into more specialized cells, including osteoblasts, adipocytes, and chondrocytes, which are essential for bone, fat, and cartilage tissues, respectively. Furthermore, they contribute to the vascular and lymphatic systems through the formation of pericytes and lymphatic endothelial cells, securing the integrity of the circulatory system.\nIn the field of regenerative medicine, mesenchymal cells, particularly mesenchymal stem cells (MSCs), are of great interest due to their unique therapeutic potential. MSCs, for instance, have been implicated in wound healing and tissue repair because of their capacity to modulate the immune response. They can secrete a range of proteins and growth factors that aid in angiogenesis, the formation of new blood vessels, and the stimulation of resident progenitor cells to aid in tissue restoration.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesenchymal cell" @@ -3639,7 +4460,13 @@ "val" : "Neural crest cells are a group of transient and highly migratory cells that originate from the neuroectoderm during the early stages of embryonic development. They are multipotent cells with an exceptional degree of plasticity, capable of differentiating into various somatic cell types and therefore play a fundamental role in the formation of various organs and tissues, making them critical contributors to the developing embryo. \nAfter the initiation of neurulation (the formation of the neural tube) neural crest cells start to undergo epithelial-to-mesenchymal transition and delaminate and migrate from the dorsal neural tube to several regions throughout the embryo. They differentiate into a range of diverse cell types, such as neurons and glial cells of the peripheral nervous system, including sensory and autonomic neurons. They also contribute to the formation of adrenal glands, pigment cells in the skin (melanocytes), cardiac structures, including parts of the heart septum and major arteries, as well as bones and cartilage of the face and skull.\nDisorders or aberrations in the development or migration of the neural crest cells can lead to serious congenital malformations, such as neurocristopathies, including Hirschsprung disease, neuroblastoma, and neurofibromatosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "neural crest cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "neural crest cell" @@ -3778,7 +4605,13 @@ "val" : "Conjunctival epithelial cells are located in the outermost layer of the conjunctiva, the transparent mucous membrane that covers the front surface of the eye (sclera) and lines the inside of the eyelids. Depending on the location, the conjunctival epithelium varies from a stratified squamous non-keratinizing epithelium (close to the lid margin) to a stratified columnar epithelium (bulbar). It consists of between two and seven layers of epithelial cells, which are organized into three main types: basal, intermediate and superficial; amongst them are goblet cells, which produce the mucous layer of the tear film, \nThe conjunctival cells play a vital role in preserving the health and functionality of the eye, contributing significantly to ocular defense mechanisms. They also participate in maintaining the ocular surface's physiological environment. Specifically, conjunctival epithelial cells serve as a physical barrier against environmental threats, such as dust, allergens, and microbes. They prevent foreign bodies from entering the eye, thanks to their tightly packed arrangement, which is integral to the eye's first line of defense. \nApart from this physical protection, these conjunctival epithelial cells are also involved in immune defense. They secrete microbicidal and immunomodulatory peptides and cytokines and can recognize and respond to pathogens through their Toll- and NOD-like receptor signaling pathways and modulate DC and lymphocyte function. \nAdditionally, conjunctival goblet cells, assist in maintaining ocular surface moisture by secreting soluble mucins for tear film production, a thin fluid layer that keeps the cornea and conjunctiva moist. This tear film lubricates the eye, protects against infections, and ensures uninterrupted, clear vision.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000432" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000432", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "conjunctival epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3804,7 +4637,13 @@ "val" : "Ciliary muscle cells are specialized contractile cells that constitute the ciliary muscle, a component of the eye in vertebrates. These cells form a ring around the iris, the eye's colored part. Ciliary muscle cells fall into the category of smooth muscle cells, characterized by their lack of the striations typical of skeletal and cardiac muscle cells. Their shape is elongated and pointed at both ends, and they occur in multi-nucleated syncytia where many cells share the same cytoplasm.\nCiliary muscle cells primarily control the eye's accommodation, adjusting the thickness and curvature of the lens to fine-tune the focus of light on the retina. When ciliary muscle cells contract, tension on the zonular fibers holding the lens in place is reduced, allowing the lens to become thicker and increase its refractive power. Conversely, when the ciliary muscle cells relax, the tension on the zonular fibers increases, causing the lens to become flatter and decrease its refractive power. This adjustment facilitates clear vision at different distances, ranging from near to far objects.\nAdditionally, ciliary muscle cells play a role in draining the eye's aqueous humor, which is the clear fluid that fills the anterior chamber of the eye between the cornea and the lens. By controlling the shape of the surrounding trabecular meshwork through muscle contractions and relaxations, ciliary muscle cells indirectly regulate intraocular pressure, a factor critical for preventing ocular conditions like glaucoma.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000443" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000443", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ciliary muscle cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3893,7 +4732,13 @@ }, { "val" : "MetaCyc:PEPTIDYLTRANSFERASE-RXN" }, { - "val" : "Reactome:R-HSA-156912" + "val" : "Reactome:R-HSA-156912", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Peptide transfer from P-site tRNA to the A-site tRNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -3901,6 +4746,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25493" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -3949,7 +4797,13 @@ "val" : "mitosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-69278" + "val" : "Reactome:R-HSA-69278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle, Mitotic" + } ] + } }, { "val" : "Wikipedia:Mitosis" } ], @@ -4139,7 +4993,13 @@ "xrefs" : [ "GOC:dph", "GOC:sdb_2009", "GOC:tb" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9823730" + "val" : "Reactome:R-HSA-9823730", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Formation of definitive endoderm" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -4517,6 +5377,9 @@ "val" : "molecular function" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is the same as GO molecular function" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -5144,7 +6007,13 @@ "val" : "protein translation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72766" + "val" : "Reactome:R-HSA-72766", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Translation" + } ] + } }, { "val" : "Wikipedia:Translation_(genetics)" } ], @@ -5177,7 +6046,13 @@ "val" : "translation initiation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72613" + "val" : "Reactome:R-HSA-72613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Initiation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5202,7 +6077,13 @@ "val" : "translation elongation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-156842" + "val" : "Reactome:R-HSA-156842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Elongation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5229,7 +6110,13 @@ "val" : "translational complex disassembly" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72764" + "val" : "Reactome:R-HSA-72764", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Termination" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5283,7 +6170,13 @@ "val" : "single-organism transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382551" + "val" : "Reactome:R-HSA-382551", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of small molecules" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -5311,7 +6204,13 @@ "val" : "ion transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-425393" + "val" : "Reactome:R-HSA-425393", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of inorganic cations/anions and amino acids/oligopeptides" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5351,15 +6250,45 @@ "val" : "sodium:neurotransmitter transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-181429" - }, { - "val" : "Reactome:R-HSA-181430" - }, { - "val" : "Reactome:R-HSA-210500" - }, { - "val" : "Reactome:R-HSA-212676" - }, { - "val" : "Reactome:R-HSA-264642" + "val" : "Reactome:R-HSA-181429", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Serotonin Neurotransmitter Release Cycle" + } ] + } + }, { + "val" : "Reactome:R-HSA-181430", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Norepinephrine Neurotransmitter Release Cycle" + } ] + } + }, { + "val" : "Reactome:R-HSA-210500", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Glutamate Neurotransmitter Release Cycle" + } ] + } + }, { + "val" : "Reactome:R-HSA-212676", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Dopamine Neurotransmitter Release Cycle" + } ] + } + }, { + "val" : "Reactome:R-HSA-264642", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Acetylcholine Neurotransmitter Release Cycle" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5377,7 +6306,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { - 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"val" : "Reactome:R-HSA-159431" - }, { - "val" : "Reactome:R-HSA-192312" - }, { - "val" : "Reactome:R-HSA-193491" - }, { - "val" : "Reactome:R-HSA-8858298" + "val" : "Reactome:R-HSA-159431", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine" + } ] + } + }, { + "val" : "Reactome:R-HSA-192312", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate" + } ] + } + }, { + "val" : "Reactome:R-HSA-193491", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate" + } ] + } + }, { + "val" : "Reactome:R-HSA-8858298", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "HRASLS transfer acyl group from PC to PE to form NAPE" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/20486" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -7207,6 +8344,9 @@ "val" : "EC:2.3.2.-" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -7291,7 +8431,13 @@ "val" : "multicellular organismal protein metabolic process" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-392499" + "val" : "Reactome:R-HSA-392499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of proteins" + } ] + } }, { "val" : "Wikipedia:Protein_metabolism" } ], @@ -7553,7 +8699,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -7567,6 +8713,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/26279" }, { @@ -7583,6 +8732,7 @@ "val" : "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:18391171" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "formation of a cell surface projection" @@ -7592,6 +8742,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8213,6 +9366,9 @@ "val" : "protein-protein complex" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is not covalently bonded, which conflicts with changes to the parent definition." + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -8277,7 +9433,13 @@ "val" : "ATP hydrolysis coupled ion transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-983712" + "val" : "Reactome:R-HSA-983712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ion channel transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -8444,6 +9606,9 @@ "val" : "Wikipedia:Melanosome" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002161", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6237" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -8454,8 +9619,8 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "Any biological process involved in the maintenance of an internal steady state.", - "xrefs" : [ "GOC:jl", "ISBN:0395825172" ] + "val" : "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions.", + "xrefs" : [ "PMID:26265027" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_mouse" ], "synonyms" : [ { @@ -8478,6 +9643,9 @@ "val" : "regulation of homeostatic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/31175" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8601,7 +9769,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -8613,6 +9781,9 @@ "val" : "cellular projection" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" }, { @@ -10207,7 +11378,13 @@ "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953897" + "val" : "Reactome:R-HSA-8953897", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cellular responses to stimuli" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -10252,11 +11429,29 @@ "val" : "ATP hydrolysis coupled transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382556" + "val" : "Reactome:R-HSA-382556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ABC-family proteins mediated transport" + } ] + } }, { - "val" : "Reactome:R-HSA-425407" + "val" : "Reactome:R-HSA-425407", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "SLC-mediated transmembrane transport" + } ] + } }, { - "val" : "Reactome:R-HSA-5223345" + "val" : "Reactome:R-HSA-5223345", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Miscellaneous transport and binding events" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", @@ -10750,7 +11945,7 @@ "meta" : { "definition" : { "val" : "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.", - "xrefs" : [ "GOC:BHF", "GOC:mah", "PMID:20236620" ] + "xrefs" : [ "GOC:BHF", "PMID:12082143", "PMID:16893474", "PMID:20236620" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", @@ -10762,6 +11957,9 @@ "xrefs" : [ "GOC:BHF" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/31135" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-10-11T11:44:57Z" }, { @@ -10861,11 +12059,29 @@ "val" : "induction of apoptosis by extracellular signals" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-193681" + "val" : "Reactome:R-HSA-193681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ceramide signalling" + } ] + } }, { - "val" : "Reactome:R-HSA-204998" + "val" : "Reactome:R-HSA-204998", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell death signalling via NRAGE, NRIF and NADE" + } ] + } }, { - "val" : "Reactome:R-HSA-75157" + "val" : "Reactome:R-HSA-75157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "FasL/ CD95L signaling" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -10895,7 +12111,13 @@ "val" : "apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-75153" + "val" : "Reactome:R-HSA-75153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptotic execution phase" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -11023,7 +12245,7 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098643", - "lbl" : "fibrillar collagen", + "lbl" : "fibrillar collagen complex", "type" : "CLASS", "meta" : { "definition" : { @@ -11033,6 +12255,9 @@ "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "banded collagen fibril" + }, { + "pred" : "hasExactSynonym", + "val" : "fibrillar collagen" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -11076,14 +12301,21 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098645", - "lbl" : "collagen network", + "lbl" : "complex of network-forming collagens", "type" : "CLASS", "meta" : { "definition" : { "val" : "A supramolecular complex that consists of collagen triple helices associated to form a network.", "xrefs" : [ "GOC:dos", "PMID:21421911" ] }, + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "collagen network" + } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30938" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -11277,8 +12509,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.", - "xrefs" : [ "GOC:kmv" ] + "val" : "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { @@ -11286,6 +12517,12 @@ "val" : "cellular anatomical entity" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Overlaps with some cellular components from GO" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" }, { @@ -11534,6 +12771,29 @@ "val" : "cellular_component" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/GO_0140149", + "lbl" : "non-collagenous component of interstitial matrix", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin.", + "xrefs" : [ "PMID:21123617", "PMID:25701227", "PMID:33605520", "PMID:39223427" ] + }, + "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/29491" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30146" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2025-03-20T13:08:49Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "cellular_component" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140151", "lbl" : "solid phase of interstitial matrix", @@ -11910,6 +13170,37 @@ "val" : "Euteleostomi" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_119089", + "lbl" : "Chromadorea", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Adenophorea" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794", + "lbl" : "Ecdysozoa", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_131567", "lbl" : "cellular organisms", @@ -12129,6 +13420,32 @@ "val" : "ncbi_taxonomy" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116", + "lbl" : "Rhabditina", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119", + "lbl" : "Rhabditomorpha", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "lbl" : "Eukaryota", @@ -12174,6 +13491,46 @@ "val" : "Eukaryota" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "lbl" : "Choanoflagellata", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "choanoflagellates" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellatea" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellida" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanomonada" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanozoa" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "choanoflagellates" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + }, { + "val" : "PMID:27765632" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "lbl" : "Euarchontoglires", @@ -12366,6 +13723,19 @@ "val" : "Bilateria" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_33317", + "lbl" : "Protostomia", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_33511", "lbl" : "Deuterostomia", @@ -12625,6 +13995,32 @@ "val" : "ncbi_taxonomy" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_55879", + "lbl" : "Rhabditoidea", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_55885", + "lbl" : "Peloderinae", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6072", "lbl" : "Eumetazoa", @@ -12641,6 +14037,88 @@ "val" : "Eumetazoa" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6231", + "lbl" : "Nematoda", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "nematode" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "nematodes" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "roundworm" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "roundworms" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Nemata" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "nematodes" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6236", + "lbl" : "Rhabditida", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Strongylida" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6237", + "lbl" : "Caenorhabditis", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6243", + "lbl" : "Rhabditidae", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_7711", "lbl" : "Chordata", @@ -13322,6 +14800,21 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0001591", + "lbl" : "curvature", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.", + "xrefs" : [ "WordNet:WordNet" ] + }, + "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0001690", "lbl" : "contractile", @@ -13659,6 +15152,32 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0002254", + "lbl" : "flattened", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane.", + "xrefs" : [ "PATOC:CVS" ] + }, + "comments" : [ "Becoming flat but not necessarily completely flat." ], + "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], + "synonyms" : [ { + "pred" : "hasRelatedSynonym", + "val" : "compressed" + } ], + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0002-2061-091X" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2010-08-16T03:59:34Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002266", "lbl" : "3-D shape", @@ -15064,9 +16583,24 @@ }, { "val" : "TAO:0000107" }, { - "val" : "UMLS:C0015392" - }, { - "val" : "UMLS:C1280202" + "val" : "UMLS:C0015392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1169" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Eye" + } ] + } + }, { + "val" : "UMLS:C1280202", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1169" + } ] + } }, { "val" : "VHOG:0000275" }, { @@ -15143,7 +16677,13 @@ }, { "val" : "EMAPA:35955" }, { - "val" : "FBbt:00005155" + "val" : "FBbt:00005155", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "GAID:63" }, { @@ -15157,7 +16697,13 @@ }, { "val" : "SCTID:244485009" }, { - "val" : "UMLS:C0935626" + "val" : "UMLS:C0935626", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_of_the_Special_Sense" + } ] + } }, { "val" : "VHOG:0001407" }, { @@ -15263,7 +16809,16 @@ }, { "val" : "TGMA:0000002" }, { - "val" : "UMLS:C0018670" + "val" : "UMLS:C0018670", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1230" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Head" + } ] + } }, { "val" : "VHOG:0001644" }, { @@ -15317,7 +16872,13 @@ }, { "val" : "TAO:0005425" }, { - "val" : "UMLS:C0036760" + "val" : "UMLS:C0036760", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Serosa" + } ] + } }, { "val" : "Wikipedia:Serous_membrane" }, { @@ -15403,7 +16964,13 @@ "xrefs" : [ { "val" : "AAO:0011123" }, { - "val" : "FBbt:00100314" + "val" : "FBbt:00100314", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:30320" }, { @@ -15413,7 +16980,13 @@ }, { "val" : "TAO:0005171" }, { - "val" : "UMLS:C0687028" + "val" : "UMLS:C0687028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Duct" + } ] + } }, { "val" : "Wikipedia:Duct_(anatomy)" }, { @@ -15493,7 +17066,13 @@ }, { "val" : "FAO:0000001" }, { - "val" : "FBbt:00007001" + "val" : "FBbt:00007001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:305751" }, { @@ -15578,7 +17157,13 @@ }, { "val" : "SCTID:272625005" }, { - "val" : "UMLS:C0178784" + "val" : "UMLS:C0178784", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ" + } ] + } }, { "val" : "WBbt:0003760" }, { @@ -15586,7 +17171,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33090" @@ -15706,47 +17297,161 @@ }, { "val" : "BilaDO:0000004" }, { - "val" : "BtauDv:0000078" - }, { - "val" : "CfamDv:0000007" - }, { - "val" : "ChirDv:0000014" - }, { - "val" : "DpseDv:0000005" - }, { - "val" : "DsimDv:0000005" + "val" : "BtauDv:0000078", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001272" }, { - "val" : "EcabDv:0000007" + "val" : "EcabDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005369" }, { - "val" : "FcatDv:0000007" - }, { - "val" : "GgalDv:0000076" - }, { - "val" : "GgorDv:0000032" - }, { - "val" : "HsapDv:0010000" 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[ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : 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"https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EV:0300001" }, { - "val" : "EcabDv:0000002" + "val" : "EcabDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005289" }, { "val" : "FMA:72652" }, { - "val" : "FcatDv:0000002" - }, { - "val" : "GgalDv:0000002" - }, { - "val" : "GgorDv:0000002" - }, { - "val" : "HsapDv:0000045" - }, { - "val" : "MdomDv:0000002" - }, { - "val" : "MmulDv:0000002" - }, { - "val" : "MmusDv:0000042" + "val" : "FcatDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000045", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000042", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000000" }, { "val" : "OGES:000022" }, { - "val" : "OanaDv:0000002" - }, { - "val" : "OariDv:0000002" - }, { - "val" : "OcunDv:0000002" - }, { - "val" : "PpanDv:0000002" - }, { - "val" : "PtroDv:0000002" - }, { - "val" : "RnorDv:0000002" + "val" : "OanaDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "SCTID:296280003" }, { - "val" : "SsalDv:0000002" - }, { - "val" : "SscrDv:0000002" + "val" : "SsalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000003" }, { @@ -15905,7 +17748,13 @@ }, { "val" : "SCTID:25087005" }, { - "val" : "UMLS:C1518256" + "val" : "UMLS:C1518256", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System_Part" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -15943,7 +17792,13 @@ }, { "val" : "SCTID:118966000" }, { - "val" : "UMLS:C1519343" + "val" : "UMLS:C1519343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System_Part" + } ] + } }, { "val" : "galen:ComplexSkeletalStructure" } ], @@ -15991,7 +17846,13 @@ }, { "val" : "NCIT:C34309" }, { - "val" : "UMLS:C1515087" + "val" : "UMLS:C1515087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Surface_Ectoderm" + } ] + } }, { "val" : "Wikipedia:External_ectoderm" } ], @@ -16034,7 +17895,13 @@ }, { "val" : "OGES:000024" }, { - "val" : "SsalDv:0000038" + "val" : "SsalDv:0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000022" }, { @@ -16104,55 +17971,193 @@ "val" : "lifespan" } ], "xrefs" : [ { - "val" : "AcarDv:0000001" - }, { - "val" : "BtauDv:0000001" - }, { - "val" : "CfamDv:0000001" - }, { - "val" : "ChirDv:0000001" - }, { - "val" : "CporDv:0000001" - }, { - "val" : "DpseDv:0000001" - }, { - "val" : "DsimDv:0000001" - }, { - "val" : "EcabDv:0000001" + "val" : "AcarDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "BtauDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "EcabDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00000000" }, { - "val" : "FcatDv:0000001" - }, { - "val" : "GgalDv:0000001" - }, { - "val" : "GgorDv:0000001" - }, { - "val" : "HsapDv:0000001" - }, { - "val" : "MdomDv:0000001" - }, { - "val" : "MmulDv:0000001" - }, { - "val" : "MmusDv:0000001" + "val" : "FcatDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000011" }, { - "val" : "OanaDv:0000001" - }, { - "val" : "OariDv:0000001" - }, { - "val" : "OcunDv:0000001" - }, { - "val" : "PpanDv:0000001" - }, { - "val" : "PtroDv:0000001" - }, { - "val" : "RnorDv:0000001" - }, { - "val" : "SsalDv:0000001" - }, { - "val" : "SscrDv:0000001" + "val" : "OanaDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "ncithesaurus:Life" } ], @@ -16191,63 +18196,201 @@ "val" : "stage" } ], "xrefs" : [ { - "val" : "AcarDv:0000000" + "val" : "AcarDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BILS:0000105" }, { - "val" : "BtauDv:0000000" - }, { - "val" : "CfamDv:0000000" - }, { - "val" : "ChirDv:0000000" - }, { - "val" : "CporDv:0000000" - }, { - "val" : "DpseDv:0000000" - }, { - "val" : "DsimDv:0000000" + "val" : "BtauDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0000399" }, { - "val" : "EcabDv:0000000" + "val" : "EcabDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00007012" }, { "val" : "FMA:24120" }, { - "val" : "FcatDv:0000000" - }, { - "val" : "GgalDv:0000000" - }, { - "val" : "GgorDv:0000000" - }, { - "val" : "HsapDv:0000000" + "val" : "FcatDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D008018" }, { - "val" : "MdomDv:0000000" - }, { - "val" : "MmulDv:0000000" - }, { - "val" : "MmusDv:0000000" - }, { - "val" : "OanaDv:0000000" - }, { - "val" : "OariDv:0000000" - }, { - "val" : "OcunDv:0000000" + "val" : "MdomDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000090" }, { - "val" : "PpanDv:0000000" - }, { - "val" : "PtroDv:0000000" - }, { - "val" : "RnorDv:0000000" - }, { - "val" : "SsalDv:0000000" - }, { - "val" : "SscrDv:0000000" + "val" : "PpanDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000002" }, { @@ -16318,7 +18461,13 @@ }, { "val" : "BilaDO:0000005" }, { - "val" : "ChirDv:0000003" + "val" : "ChirDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001322" }, { @@ -16326,21 +18475,57 @@ }, { "val" : "FBdv:00005288" }, { - "val" : "HsapDv:0000003" - }, { - "val" : "MmusDv:0000003" + "val" : "HsapDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "NCIT:C12601" }, { - "val" : "OariDv:0000009" + "val" : "OariDv:0000009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000100" }, { - "val" : "RnorDv:0000048" - }, { - "val" : "SsalDv:0000003" - }, { - "val" : "SscrDv:0000087" + "val" : "RnorDv:0000048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "VHOG:0000745" }, { @@ -16373,33 +18558,81 @@ }, { "val" : "BilaDO:0000006" }, { - "val" : "ChirDv:0000004" + "val" : "ChirDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001290" }, { "val" : "FBdv:00000054" }, { - "val" : "GgalDv:0000064" - }, { - "val" : "HsapDv:0000005" + "val" : "GgalDv:0000064", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D002970" }, { - "val" : "MmusDv:0000004" + "val" : "MmusDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000015" }, { "val" : "OGES:000020" }, { - "val" : "OariDv:0000010" + "val" : "OariDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000200" }, { - "val" : "RnorDv:0000049" - }, { - "val" : "SsalDv:0000004" - }, { - "val" : "SscrDv:0000088" + "val" : "RnorDv:0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000088", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Cleavage_(embryo)" }, { @@ -16427,15 +18660,39 @@ }, { "val" : "BilaDO:0000007" }, { - "val" : "ChirDv:0000010" + "val" : "ChirDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001282" }, { - "val" : "GgalDv:0000091" - }, { - "val" : "HsapDv:0000006" - }, { - "val" : "MmusDv:0000007" + "val" : "GgalDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000003" }, { @@ -16443,13 +18700,37 @@ }, { "val" : "OGES:000021" }, { - "val" : "OariDv:0000025" - }, { - "val" : "RnorDv:0000054" - }, { - "val" : "SsalDv:0000012" - }, { - "val" : "SscrDv:0000089" + "val" : "OariDv:0000025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000005" }, { @@ -16510,29 +18791,77 @@ }, { "val" : "BilaDO:0000008" }, { - "val" : "ChirDv:0000011" + "val" : "ChirDv:0000011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001296" }, { "val" : "FBdv:00005317" }, { - "val" : "GgalDv:0000092" - }, { - "val" : "HsapDv:0000010" - }, { - "val" : "MmusDv:0000013" + "val" : "GgalDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000004" }, { "val" : "OGES:000019" }, { - "val" : "OariDv:0000026" - }, { - "val" : "RnorDv:0000005" - }, { - "val" : "SsalDv:0000016" - }, { - "val" : "SscrDv:0000090" + "val" : "OariDv:0000026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000010" }, { @@ -16559,19 +18888,61 @@ }, { "val" : "BilaDO:0000009" }, { - "val" : "ChirDv:0000012" - }, { - "val" : "GgalDv:0000093" - }, { - "val" : "HsapDv:0000012" - }, { - "val" : "MmusDv:0000017" - }, { - "val" : "OariDv:0000027" - }, { - "val" : "RnorDv:0000007" - }, { - "val" : "SscrDv:0000091" + "val" : "ChirDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "XAO:1000006" } ], @@ -16604,25 +18975,73 @@ }, { "val" : "BilaDO:0000010" }, { - "val" : "ChirDv:0000013" - }, { - "val" : "GgalDv:0000094" - }, { - "val" : "HsapDv:0000015" - }, { - "val" : "MmusDv:0000018" + "val" : "ChirDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000018", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000005" }, { "val" : "OGES:000032" }, { - "val" : "OariDv:0000028" - }, { - "val" : "RnorDv:0000055" - }, { - "val" : "SsalDv:0000022" - }, { - "val" : "SscrDv:0000086" + "val" : "OariDv:0000028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Organogenesis" } ], @@ -16660,7 +19079,13 @@ "xrefs" : [ { "val" : "CARO:0001001" }, { - "val" : "FBbt:00005099" + "val" : "FBbt:00005099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "NLX:147821" } ], @@ -16773,7 +19198,13 @@ }, { "val" : "EMAPA:16262" }, { - "val" : "FBbt:00003126" + "val" : "FBbt:00003126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:49184" }, { @@ -16889,7 +19320,13 @@ }, { "val" : "TAO:0000007" }, { - "val" : "UMLS:C0005767" + "val" : "UMLS:C0005767", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood" + } ] + } }, { "val" : "VHOG:0000224" }, { @@ -17079,7 +19516,13 @@ "xrefs" : [ { "val" : "BTO:0001837" }, { - "val" : "EMAPA:37950" + "val" : "EMAPA:37950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:62889" }, { @@ -17148,7 +19591,13 @@ }, { "val" : "NCIT:C34062" }, { - "val" : "UMLS:C1516992" + "val" : "UMLS:C1516992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland_Fluid_or_Secretion" + } ] + } }, { "val" : "galen:Secretion" } ], @@ -17203,7 +19652,13 @@ }, { "val" : "EMAPA:35178" }, { - "val" : "FBbt:00007019" + "val" : "FBbt:00007019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9669" }, { @@ -17277,7 +19732,13 @@ }, { "val" : "EHDAA2:0003005" }, { - "val" : "FBbt:00007017" + "val" : "FBbt:00007017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:5897" }, { @@ -17289,7 +19750,13 @@ }, { "val" : "TGMA:0001825" }, { - "val" : "UMLS:C0524461" + "val" : "UMLS:C0524461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lumen_Space" + } ] + } }, { "val" : "VHOG:0001728" }, { @@ -17332,7 +19799,13 @@ }, { "val" : "EHDAA2:0003006" }, { - "val" : "FBbt:00007016" + "val" : "FBbt:00007016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67165" }, { @@ -17384,7 +19857,13 @@ }, { "val" : "EHDAA2:0003007" }, { - "val" : "FBbt:00007015" + "val" : "FBbt:00007015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67112" }, { @@ -17464,7 +19943,13 @@ }, { "val" : "EV:0100000" }, { - "val" : "FBbt:00004856" + "val" : "FBbt:00004856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7149" }, { @@ -17480,7 +19965,13 @@ }, { "val" : "TGMA:0001831" }, { - "val" : "UMLS:C0460002" + "val" : "UMLS:C0460002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_System" + } ] + } }, { "val" : "VHOG:0001725" }, { @@ -17578,7 +20069,13 @@ }, { "val" : "EV:0100016" }, { - "val" : "FBbt:00000001" + "val" : "FBbt:00000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:256135" }, { @@ -17670,7 +20167,13 @@ }, { "val" : "EMAPA:36031" }, { - "val" : "FBbt:00007009" + "val" : "FBbt:00007009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7153" }, { @@ -17690,7 +20193,13 @@ }, { "val" : "TGMA:0001840" }, { - "val" : "UMLS:C0229962" + "val" : "UMLS:C0229962", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Body_Part" + } ] + } }, { "val" : "VHOG:0001758" }, { @@ -17746,7 +20255,13 @@ }, { "val" : "EHDAA2:0003040" }, { - "val" : "FBbt:00007013" + "val" : "FBbt:00007013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:63863" }, { @@ -17785,7 +20300,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007277" + "val" : "FBbt:00007277", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "VHOG:0001737" } ], @@ -17844,7 +20365,13 @@ }, { "val" : "EMAPA:35868" }, { - "val" : "FBbt:00007003" + "val" : "FBbt:00007003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9637" }, { @@ -17860,7 +20387,13 @@ }, { "val" : "TGMA:0001844" }, { - "val" : "UMLS:C0040300" + "val" : "UMLS:C0040300", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Tissue" + } ] + } }, { "val" : "VHOG:0001757" }, { @@ -17916,7 +20449,13 @@ }, { "val" : "EHDAA2:0003055" }, { - "val" : "FBbt:00007010" + "val" : "FBbt:00007010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000055" }, { @@ -17982,7 +20521,13 @@ }, { "val" : "EMAPA:32738" }, { - "val" : "FBbt:00007005" + "val" : "FBbt:00007005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9639" }, { @@ -18000,7 +20545,13 @@ }, { "val" : "TAO:0001486" }, { - "val" : "UMLS:C0014609" + "val" : "UMLS:C0014609", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Epithelium" + } ] + } }, { "val" : "VHOG:0000387" }, { @@ -18059,7 +20610,13 @@ }, { "val" : "TAO:0001494" }, { - "val" : "UMLS:C0682575" + "val" : "UMLS:C0682575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stratified_Epithelium" + } ] + } }, { "val" : "Wikipedia:Stratified_epithelium" }, { @@ -18112,7 +20669,13 @@ }, { "val" : "TAO:0001498" }, { - "val" : "UMLS:C0836133" + "val" : "UMLS:C0836133", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_squamous_epithelium" }, { @@ -18266,7 +20829,13 @@ }, { "val" : "TAO:0001495" }, { - "val" : "UMLS:C0682574" + "val" : "UMLS:C0682574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Epithelium" + } ] + } }, { "val" : "XAO:0004007" }, { @@ -18366,7 +20935,13 @@ }, { "val" : "EMAPA:16039" }, { - "val" : "FBbt:00000052" + "val" : "FBbt:00000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69068" }, { @@ -18384,7 +20959,13 @@ }, { "val" : "SCTID:57991002" }, { - "val" : "UMLS:C0013935" + "val" : "UMLS:C0013935", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryo" + } ] + } }, { "val" : "VHOG:0001766" }, { @@ -18446,7 +21027,13 @@ }, { "val" : "EMAPA:36033" }, { - "val" : "FBbt:00000110" + "val" : "FBbt:00000110", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69069" }, { @@ -18460,9 +21047,21 @@ }, { "val" : "TAO:0001122" }, { - "val" : "UMLS:C0920502" - }, { - "val" : "UMLS:C1708239" + "val" : "UMLS:C0920502", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Tissue" + } ] + } + }, { + "val" : "UMLS:C1708239", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Germinal_Layer" + } ] + } }, { "val" : "VHOG:0001223" }, { @@ -18509,7 +21108,13 @@ }, { "val" : "EV:0100003" }, { - "val" : "FBbt:00000111" + "val" : "FBbt:00000111", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69070" }, { @@ -18529,7 +21134,13 @@ }, { "val" : "TAO:0000016" }, { - "val" : "UMLS:C0013574" + "val" : "UMLS:C0013574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ectoderm" + } ] + } }, { "val" : "VHOG:0000153" }, { @@ -18580,7 +21191,13 @@ }, { "val" : "EV:0100005" }, { - "val" : "FBbt:00000125" + "val" : "FBbt:00000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69071" }, { @@ -18598,7 +21215,13 @@ }, { "val" : "TAO:0000017" }, { - "val" : "UMLS:C0014144" + "val" : "UMLS:C0014144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endoderm" + } ] + } }, { "val" : "VHOG:0000154" }, { @@ -18664,7 +21287,13 @@ }, { "val" : "EV:0100006" }, { - "val" : "FBbt:00000126" + "val" : "FBbt:00000126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69072" }, { @@ -18682,7 +21311,13 @@ }, { "val" : "TAO:0000041" }, { - "val" : "UMLS:C0025485" + "val" : "UMLS:C0025485", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesoderm" + } ] + } }, { "val" : "VHOG:0000152" }, { @@ -18752,7 +21387,13 @@ }, { "val" : "EMAPA:16263" }, { - "val" : "FBbt:00000439" + "val" : "FBbt:00000439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:295846" }, { @@ -18762,7 +21403,13 @@ }, { "val" : "TGMA:0000135" }, { - "val" : "UMLS:C1514977" + "val" : "UMLS:C1514977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stomodeum" + } ] + } }, { "val" : "Wikipedia:Stomodeum" }, { @@ -18885,7 +21532,16 @@ }, { "val" : "TAO:0000435" }, { - "val" : "UMLS:C0029130" + "val" : "UMLS:C0029130", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1640" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Nerve" + } ] + } }, { "val" : "VHOG:0000543" }, { @@ -18895,7 +21551,13 @@ }, { "val" : "ZFA:0000435" }, { - "val" : "neuronames:289" + "val" : "neuronames:289", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1640" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -18972,7 +21634,13 @@ }, { "val" : "TAO:0000114" }, { - "val" : "UMLS:C0018787" + "val" : "UMLS:C0018787", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Heart" + } ] + } }, { "val" : "VHOG:0000276" }, { @@ -19065,7 +21733,13 @@ }, { "val" : "EV:0100164" }, { - "val" : "FBbt:00005095" + "val" : "FBbt:00005095", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:50801" }, { @@ -19093,9 +21767,24 @@ }, { "val" : "TAO:0000008" }, { - "val" : "UMLS:C0006104" - }, { - "val" : "UMLS:C1269537" + "val" : "UMLS:C0006104", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:796" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Brain" + } ] + } + }, { + "val" : "UMLS:C1269537", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:796" + } ] + } }, { "val" : "VHOG:0000157" }, { @@ -19107,7 +21796,13 @@ }, { "val" : "galen:Brain" }, { - "val" : "neuronames:21" + "val" : "neuronames:21", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:796" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -19238,7 +21933,16 @@ }, { "val" : "TAO:0000556" }, { - "val" : "UMLS:C0029126" + "val" : "UMLS:C0029126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1416" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Chiasm" + } ] + } }, { "val" : "VHOG:0000190" }, { @@ -19248,7 +21952,13 @@ }, { "val" : "ZFA:0000556" }, { - "val" : "neuronames:459" + "val" : "neuronames:459", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1416" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -19318,7 +22028,13 @@ }, { "val" : "TAO:0000640" }, { - "val" : "UMLS:C0010031" + "val" : "UMLS:C0010031", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cornea" + } ] + } }, { "val" : "VHOG:0000164" }, { @@ -19411,7 +22127,13 @@ }, { "val" : "TAO:0000035" }, { - "val" : "UMLS:C0023317" + "val" : "UMLS:C0023317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Crystalline_Lens" + } ] + } }, { "val" : "VHOG:0000169" }, { @@ -19503,9 +22225,24 @@ }, { "val" : "TAO:0000152" }, { - "val" : "UMLS:C0035298" - }, { - "val" : "UMLS:C1278894" + "val" : "UMLS:C0035298", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1153" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Retina" + } ] + } + }, { + "val" : "UMLS:C1278894", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1153" + } ] + } }, { "val" : "VHOG:0000229" }, { @@ -19560,7 +22297,13 @@ }, { "val" : "EV:0100336" }, { - "val" : "FBbt:00005162" + "val" : "FBbt:00005162", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "GAID:69" }, { @@ -19639,7 +22382,13 @@ }, { "val" : "TAO:0000367" }, { - "val" : "UMLS:C0022417" + "val" : "UMLS:C0022417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint" + } ] + } }, { "val" : "VHOG:0001276" }, { @@ -19692,7 +22441,13 @@ }, { "val" : "EFO:0000793" }, { - "val" : "FBbt:00005055" + "val" : "FBbt:00005055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7152" }, { @@ -19753,7 +22508,13 @@ }, { "val" : "CALOHA:TS-2103" }, { - "val" : "MESH:D002319" + "val" : "MESH:D002319", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "VHOG:0001248" }, { @@ -19761,7 +22522,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6073" @@ -19833,7 +22600,13 @@ }, { "val" : "TAO:0000548" }, { - "val" : "UMLS:C0026845" + "val" : "UMLS:C0026845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle" + } ] + } }, { "val" : "VSAO:0005038" }, { @@ -19896,7 +22669,13 @@ }, { "val" : "EV:0100162" }, { - "val" : "FBbt:00005093" + "val" : "FBbt:00005093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7157" }, { @@ -19916,7 +22695,13 @@ }, { "val" : "TAO:0000396" }, { - "val" : "UMLS:C0027763" + "val" : "UMLS:C0027763", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System" + } ] + } }, { "val" : "VHOG:0000402" }, { @@ -20000,7 +22785,13 @@ }, { "val" : "EV:0100163" }, { - "val" : "FBbt:00005094" + "val" : "FBbt:00005094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:55675" }, { @@ -20018,7 +22809,16 @@ }, { "val" : "TAO:0000012" }, { - "val" : "UMLS:C0927232" + "val" : "UMLS:C0927232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1099" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Central_Nervous_System" + } ] + } }, { "val" : "VHOG:0000293" }, { @@ -20032,7 +22832,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -20079,7 +22885,13 @@ }, { "val" : "EV:0100304" }, { - "val" : "FBbt:00005100" + "val" : "FBbt:00005100", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:83847" }, { @@ -20139,7 +22951,13 @@ }, { "val" : "TGMA:0000088" }, { - "val" : "UMLS:C1185741" + "val" : "UMLS:C1185741", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Fascicle" + } ] + } }, { "val" : "Wikipedia:Nervous_system_fascicle" } ], @@ -20208,7 +23026,13 @@ }, { "val" : "EMAPA:16192" }, { - "val" : "FBbt:00007692" + "val" : "FBbt:00007692", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:75259" }, { @@ -20279,7 +23103,13 @@ }, { "val" : "EHDAA2:0003171" }, { - "val" : "FBbt:00005495" + "val" : "FBbt:00005495", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86589" }, { @@ -20287,7 +23117,13 @@ }, { "val" : "NCIT:C34275" }, { - "val" : "UMLS:C0678727" + "val" : "UMLS:C0678727", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium" + } ] + } }, { "val" : "Wikipedia:Primordium" }, { @@ -20351,7 +23187,13 @@ }, { "val" : "TAO:0001135" }, { - "val" : "UMLS:C0231024" + "val" : "UMLS:C0231024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Tube" + } ] + } }, { "val" : "VHOG:0000307" }, { @@ -20396,7 +23238,13 @@ }, { "val" : "EHDAA2:0002229" }, { - "val" : "FBbt:10000000" + "val" : "FBbt:10000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:62955" }, { @@ -20410,7 +23258,13 @@ }, { "val" : "TGMA:0001822" }, { - "val" : "UMLS:C1515976" + "val" : "UMLS:C1515976", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Structure_System_or_Substance" + } ] + } }, { "val" : "WBbt:0000100" }, { @@ -20466,7 +23320,13 @@ }, { "val" : "TAO:0005154" }, { - "val" : "UMLS:C0039097" + "val" : "UMLS:C0039097", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Synovial_Fluid" + } ] + } }, { "val" : "Wikipedia:Synovial_fluid" }, { @@ -20550,7 +23410,13 @@ }, { "val" : "TAO:0005274" }, { - "val" : "UMLS:C1267092" + "val" : "UMLS:C1267092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Smooth_Muscle_Tissue" + } ] + } }, { "val" : "VHOG:0001246" }, { @@ -20615,7 +23481,13 @@ }, { "val" : "SCTID:361918002" }, { - "val" : "UMLS:C0086610" + "val" : "UMLS:C0086610", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesothelium" + } ] + } }, { "val" : "Wikipedia:Mesothelium" } ], @@ -20666,7 +23538,13 @@ }, { "val" : "SCTID:123961009" }, { - "val" : "UMLS:C0004600" + "val" : "UMLS:C0004600", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Back" + } ] + } }, { "val" : "Wikipedia:Dorsum_(anatomy)" }, { @@ -20723,7 +23601,13 @@ }, { "val" : "TAO:0000434" }, { - "val" : "UMLS:C0037253" + "val" : "UMLS:C0037253", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System" + } ] + } }, { "val" : "VHOG:0001254" }, { @@ -20813,7 +23697,13 @@ }, { "val" : "SCTID:302549007" }, { - "val" : "UMLS:C0015450" + "val" : "UMLS:C0015450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Face" + } ] + } }, { "val" : "Wikipedia:Face" }, { @@ -20858,7 +23748,13 @@ "xrefs" : [ "Wikipedia:Articular_capsule" ] } ], "xrefs" : [ { - "val" : "EMAPA:37621" + "val" : "EMAPA:37621", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:34836" }, { @@ -20874,7 +23770,13 @@ }, { "val" : "SCTID:182238002" }, { - "val" : "UMLS:C0206207" + "val" : "UMLS:C0206207", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint_Capsule" + } ] + } }, { "val" : "Wikipedia:Articular_capsule" }, { @@ -20940,13 +23842,25 @@ }, { "val" : "EMAPA:16247" }, { - "val" : "FBbt:00003125" + "val" : "FBbt:00003125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45615" }, { "val" : "MA:0000917" }, { - "val" : "MESH:D041981" + "val" : "MESH:D041981", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C34082" }, { @@ -20954,7 +23868,13 @@ }, { "val" : "TGMA:0001819" }, { - "val" : "UMLS:C0017189" + "val" : "UMLS:C0017189", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrointestinal_Tract" + } ] + } }, { "val" : "VHOG:0000309" }, { @@ -20966,10 +23886,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1371/journal.pone.0016309" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -21019,7 +23951,13 @@ }, { "val" : "SCTID:280862009" }, { - "val" : "UMLS:C0559230" + "val" : "UMLS:C0559230", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ciliary_Muscle" + } ] + } }, { "val" : "Wikipedia:Ciliary_muscle" } ], @@ -21050,7 +23988,13 @@ "xrefs" : [ "ZFA:0005145" ] } ], "xrefs" : [ { - "val" : "EMAPA:37474" + "val" : "EMAPA:37474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100146" }, { @@ -21140,7 +24084,13 @@ }, { "val" : "TAO:0000005" }, { - "val" : "UMLS:C0003842" + "val" : "UMLS:C0003842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Artery" + } ] + } }, { "val" : "VHOG:0001251" }, { @@ -21229,7 +24179,13 @@ }, { "val" : "TAO:0000082" }, { - "val" : "UMLS:C0042449" + "val" : "UMLS:C0042449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vein" + } ] + } }, { "val" : "VHOG:0001743" }, { @@ -21303,7 +24259,13 @@ }, { "val" : "SCTID:265782007" }, { - "val" : "UMLS:C0015426" + "val" : "UMLS:C0015426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Eyelid" + } ] + } }, { "val" : "VHOG:0000016" }, { @@ -21372,7 +24334,13 @@ }, { "val" : "SCTID:181160009" }, { - "val" : "UMLS:C0003151" + "val" : "UMLS:C0003151", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anterior_Chamber_of_the_Eye" + } ] + } }, { "val" : "VHOG:0001431" }, { @@ -21443,7 +24411,13 @@ }, { "val" : "SCTID:280648000" }, { - "val" : "UMLS:C0042160" + "val" : "UMLS:C0042160", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Uvea" + } ] + } }, { "val" : "Wikipedia:Uvea" } ], @@ -21452,7 +24426,13 @@ "val" : "TODO - check child terms, isa vs partof. See also MA:0001284 ! tunica vasculosa plexus" }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7955" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7955", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1177/0192623311409597" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "uvea" @@ -21511,7 +24491,13 @@ }, { "val" : "TAO:0001238" }, { - "val" : "UMLS:C0022077" + "val" : "UMLS:C0022077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Iris" + } ] + } }, { "val" : "VHOG:0000101" }, { @@ -21622,7 +24608,13 @@ }, { "val" : "TAO:0002187" }, { - "val" : "UMLS:C0459875" + "val" : "UMLS:C0459875", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Corneal_Epithelium" + } ] + } }, { "val" : "Wikipedia:Corneal_epithelium" }, { @@ -21675,7 +24667,13 @@ }, { "val" : "SCTID:181163006" }, { - "val" : "UMLS:C0036410" + "val" : "UMLS:C0036410", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclera" + } ] + } }, { "val" : "VHOG:0001274" }, { @@ -21746,7 +24744,13 @@ }, { "val" : "SCTID:263340007" }, { - "val" : "UMLS:C0008779" + "val" : "UMLS:C0008779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ciliary_Body" + } ] + } }, { "val" : "VHOG:0000102" }, { @@ -21834,7 +24838,13 @@ }, { "val" : "TAO:0005229" }, { - "val" : "UMLS:C0008520" + "val" : "UMLS:C0008520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Choroid" + } ] + } }, { "val" : "VHOG:0001568" }, { @@ -21903,7 +24913,13 @@ }, { "val" : "TAO:0002189" }, { - "val" : "UMLS:C0010040" + "val" : "UMLS:C0010040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Corneal_Stroma" + } ] + } }, { "val" : "Wikipedia:Corneal_stroma" }, { @@ -21951,7 +24967,13 @@ }, { "val" : "SCTID:280870004" }, { - "val" : "UMLS:C0459736" + "val" : "UMLS:C0459736", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ciliary_Epithelium" + } ] + } }, { "val" : "Wikipedia:Ciliary_body#Ciliary_epithelium" } ], @@ -22001,7 +25023,13 @@ }, { "val" : "SCTID:280657006" }, { - "val" : "UMLS:C0459649" + "val" : "UMLS:C0459649", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Retina_Layer" + } ] + } }, { "val" : "XAO:0000266" } ], @@ -22106,7 +25134,13 @@ }, { "val" : "TAO:0000144" }, { - "val" : "UMLS:C0035322" + "val" : "UMLS:C0035322", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Retinal_Pigment_Epithelium" + } ] + } }, { "val" : "VHOG:0000536" }, { @@ -22169,7 +25203,13 @@ }, { "val" : "TAO:0000143" }, { - "val" : "UMLS:C0229206" + "val" : "UMLS:C0229206", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Layer_of_the_Rods_and_Cones" + } ] + } }, { "val" : "VHOG:0001165" }, { @@ -22254,7 +25294,13 @@ }, { "val" : "TAO:0001331" }, { - "val" : "UMLS:C1518685" + "val" : "UMLS:C1518685", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Outer_Limiting_Membrane" + } ] + } }, { "val" : "Wikipedia:External_limiting_membrane" }, { @@ -22332,7 +25378,13 @@ }, { "val" : "TAO:0001464" }, { - "val" : "UMLS:C0229210" + "val" : "UMLS:C0229210", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Outer_Nuclear_Layer_of_Retina" + } ] + } }, { "val" : "VHOG:0001170" }, { @@ -22410,7 +25462,13 @@ }, { "val" : "TAO:0001330" }, { - "val" : "UMLS:C0229217" + "val" : "UMLS:C0229217", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Outer_Plexiform_Layer" + } ] + } }, { "val" : "VHOG:0001171" }, { @@ -22490,7 +25548,13 @@ }, { "val" : "TAO:0000119" }, { - "val" : "UMLS:C0229211" + "val" : "UMLS:C0229211", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Inner_Nuclear_Layer" + } ] + } }, { "val" : "VHOG:0001167" }, { @@ -22733,7 +25797,13 @@ }, { "val" : "TAO:0001029" }, { - "val" : "UMLS:C1512783" + "val" : "UMLS:C1512783", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Inner_Limiting_Membrane" + } ] + } }, { "val" : "Wikipedia:Inner_limiting_membrane" }, { @@ -22817,7 +25887,13 @@ }, { "val" : "TAO:0001329" }, { - "val" : "UMLS:C0229221" + "val" : "UMLS:C0229221", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Inner_Plexiform_Layer" + } ] + } }, { "val" : "VHOG:0001168" }, { @@ -22876,7 +25952,13 @@ }, { "val" : "SCTID:280587006" }, { - "val" : "UMLS:C0003662" + "val" : "UMLS:C0003662", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Aqueous_Humor" + } ] + } }, { "val" : "VHOG:0000548" }, { @@ -22953,11 +26035,23 @@ }, { "val" : "MA:0001286" }, { - "val" : "MESH:D014822" + "val" : "MESH:D014822", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C13323" }, { - "val" : "UMLS:C0229096" + "val" : "UMLS:C0229096", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vitreous_Humor" + } ] + } }, { "val" : "VHOG:0000795" }, { @@ -22995,7 +26089,13 @@ }, { "val" : "SCTID:181170006" }, { - "val" : "UMLS:C0042905" + "val" : "UMLS:C0042905", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vitreous_Body" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -23048,7 +26148,13 @@ "xrefs" : [ { "val" : "BTO:0002087" }, { - "val" : "EMAPA:37805" + "val" : "EMAPA:37805", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:58848" }, { @@ -23056,7 +26162,13 @@ }, { "val" : "NCIT:C33885" }, { - "val" : "UMLS:C0229095" + "val" : "UMLS:C0229095", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vitreous_Chamber" + } ] + } }, { "val" : "Wikipedia:Vitreous_chamber" } ] @@ -23109,7 +26221,13 @@ }, { "val" : "SCTID:280658001" }, { - "val" : "UMLS:C0003153" + "val" : "UMLS:C0003153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anterior_Eye_Segment" + } ] + } }, { "val" : "Wikipedia:Anterior_segment_of_eyeball" }, { @@ -23169,7 +26287,13 @@ }, { "val" : "SCTID:280659009" }, { - "val" : "UMLS:C0278450" + "val" : "UMLS:C0278450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Posterior_Eye_Segment" + } ] + } }, { "val" : "Wikipedia:Posterior_segment_of_eyeball" }, { @@ -23236,7 +26360,13 @@ }, { "val" : "SCTID:181161008" }, { - "val" : "UMLS:C0009758" + "val" : "UMLS:C0009758", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conjunctiva" + } ] + } }, { "val" : "Wikipedia:Conjunctiva" }, { @@ -23310,7 +26440,16 @@ }, { "val" : "TAO:0000109" }, { - "val" : "UMLS:C0085140" + "val" : "UMLS:C0085140", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1509" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Fore-Brain" + } ] + } }, { "val" : "VHOG:0000383" }, { @@ -23320,7 +26459,13 @@ }, { "val" : "ZFA:0000109" }, { - "val" : "neuronames:27" + "val" : "neuronames:27", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1509" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -23403,7 +26548,16 @@ }, { "val" : "TAO:0000128" }, { - "val" : "UMLS:C0025462" + "val" : "UMLS:C0025462", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1667" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesencephalon" + } ] + } }, { "val" : "VHOG:0000069" }, { @@ -23413,7 +26567,13 @@ }, { "val" : "ZFA:0000128" }, { - "val" : "neuronames:462" + "val" : "neuronames:462", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1667" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -23532,7 +26692,16 @@ }, { "val" : "TAO:0000101" }, { - "val" : "UMLS:C0012144" + "val" : "UMLS:C0012144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1503" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Diencephalon" + } ] + } }, { "val" : "VHOG:0000318" }, { @@ -23542,7 +26711,13 @@ }, { "val" : "ZFA:0000101" }, { - "val" : "neuronames:288" + "val" : "neuronames:288", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1503" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -23636,9 +26811,24 @@ }, { "val" : "TAO:0000545" }, { - "val" : "UMLS:C0025148" - }, { - "val" : "UMLS:C1269575" + "val" : "UMLS:C0025148", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:957" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Medulla_Oblongata" + } ] + } + }, { + "val" : "UMLS:C1269575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:957" + } ] + } }, { "val" : "VHOG:0000181" }, { @@ -23648,7 +26838,13 @@ }, { "val" : "ZFA:0000545" }, { - "val" : "neuronames:698" + "val" : "neuronames:698", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:957" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -23725,7 +26921,16 @@ }, { "val" : "TAO:0000252" }, { - "val" : "UMLS:C0152405" + "val" : "UMLS:C0152405", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1684" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Tract" + } ] + } }, { "val" : "VHOG:0001164" }, { @@ -23735,7 +26940,13 @@ }, { "val" : "ZFA:0000252" }, { - "val" : "neuronames:460" + "val" : "neuronames:460", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1684" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -23818,13 +27029,25 @@ }, { "val" : "MAT:0000452" }, { - "val" : "MESH:D013681" + "val" : "MESH:D013681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "SCTID:362392007" }, { "val" : "TAO:0000160" }, { - "val" : "UMLS:C0039441" + "val" : "UMLS:C0039441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1200" + } ] + } }, { "val" : "VHOG:0001367" }, { @@ -23834,7 +27057,13 @@ }, { "val" : "ZFA:0000160" }, { - "val" : "neuronames:491" + "val" : "neuronames:491", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1200" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -23895,7 +27124,13 @@ }, { "val" : "NCIT:C13356" }, { - "val" : "UMLS:C0032105" + "val" : "UMLS:C0032105", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Plasma" + } ] + } }, { "val" : "Wikipedia:Blood_plasma" } ], @@ -23937,7 +27172,13 @@ }, { "val" : "TAO:0005315" }, { - "val" : "UMLS:C0042520" + "val" : "UMLS:C0042520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venule" + } ] + } }, { "val" : "VHOG:0001765" }, { @@ -23991,7 +27232,13 @@ }, { "val" : "TAO:0002138" }, { - "val" : "UMLS:C0003847" + "val" : "UMLS:C0003847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Arteriole" + } ] + } }, { "val" : "VHOG:0001763" }, { @@ -24074,7 +27321,13 @@ }, { "val" : "TAO:0002137" }, { - "val" : "UMLS:C0005847" + "val" : "UMLS:C0005847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel" + } ] + } }, { "val" : "VHOG:0001250" }, { @@ -24140,7 +27393,13 @@ }, { "val" : "TAO:0005250" }, { - "val" : "UMLS:C0935624" + "val" : "UMLS:C0935624", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary" + } ] + } }, { "val" : "VHOG:0001253" }, { @@ -24210,7 +27469,13 @@ }, { "val" : "TAO:0002186" }, { - "val" : "UMLS:C0014259" + "val" : "UMLS:C0014259", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Corneal_Endothelium" + } ] + } }, { "val" : "Wikipedia:Corneal_endothelium" }, { @@ -24255,7 +27520,13 @@ }, { "val" : "SCTID:27168002" }, { - "val" : "UMLS:C0014257" + "val" : "UMLS:C0014257", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endothelium" + } ] + } }, { "val" : "galen:Endothelium" } ], @@ -24318,7 +27589,13 @@ }, { "val" : "EHDAA2_RETIRED:0004658" }, { - "val" : "EMAPA:37596" + "val" : "EMAPA:37596", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67242" }, { @@ -24330,7 +27607,13 @@ }, { "val" : "TAO:0002197" }, { - "val" : "UMLS:C0018220" + "val" : "UMLS:C0018220", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gray_Matter" + } ] + } }, { "val" : "VHOG:0001768" }, { @@ -24405,9 +27688,24 @@ }, { "val" : "TAO:0000029" }, { - "val" : "UMLS:C0035507" - }, { - "val" : "UMLS:C1522180" + "val" : "UMLS:C0035507", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:942" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hind-Brain" + } ] + } + }, { + "val" : "UMLS:C1522180", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:942" + } ] + } }, { "val" : "VHOG:0000070" }, { @@ -24417,11 +27715,23 @@ }, { "val" : "ZFA:0000029" }, { - "val" : "neuronames:540" + "val" : "neuronames:540", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:942" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7762" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7762", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:8932866" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -24513,7 +27823,13 @@ }, { "val" : "EFO:0000461" }, { - "val" : "FBbt:00004208" + "val" : "FBbt:00004208", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69067" }, { @@ -24529,7 +27845,13 @@ }, { "val" : "TAO:0001105" }, { - "val" : "UMLS:C0013948" + "val" : "UMLS:C0013948", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Structure" + } ] + } }, { "val" : "VSAO:0000178" }, { @@ -24593,7 +27915,13 @@ }, { "val" : "SCTID:118760003" }, { - "val" : "UMLS:C0042779" + "val" : "UMLS:C0042779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Viscera" + } ] + } }, { "val" : "Wikipedia:Viscus" }, { @@ -24632,7 +27960,13 @@ }, { "val" : "EHDAA:5049" }, { - "val" : "EMAPA:37721" + "val" : "EMAPA:37721", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71221" }, { @@ -24640,7 +27974,13 @@ }, { "val" : "MAT:0000148" }, { - "val" : "MESH:D013131" + "val" : "MESH:D013131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000148" }, { @@ -24714,7 +28054,13 @@ }, { "val" : "TAO:0001115" }, { - "val" : "UMLS:C0460005" + "val" : "UMLS:C0460005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trunk" + } ] + } }, { "val" : "Wikipedia:Torso" }, { @@ -24766,7 +28112,13 @@ }, { "val" : "TAO:0001127" }, { - "val" : "UMLS:C0587900" + "val" : "UMLS:C0587900", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Visual_System" + } ] + } }, { "val" : "Wikipedia:Visual_system" }, { @@ -24966,7 +28318,13 @@ }, { "val" : "SCTID:278858007" }, { - "val" : "UMLS:C0026860" + "val" : "UMLS:C0026860", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Musculoskeletal_System" + } ] + } }, { "val" : "VHOG:0001275" }, { @@ -25092,7 +28450,13 @@ }, { "val" : "SCTID:243949006" }, { - "val" : "UMLS:C0230139" + "val" : "UMLS:C0230139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Thoracic_Cavity" + } ] + } }, { "val" : "Wikipedia:Thoracic_cavity" } ], @@ -25200,7 +28564,16 @@ }, { "val" : "TAO:0000075" }, { - "val" : "UMLS:C0037925" + "val" : "UMLS:C0037925", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1709" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Spinal_Cord" + } ] + } }, { "val" : "VHOG:0000601" }, { @@ -25210,7 +28583,13 @@ }, { "val" : "ZFA:0000075" }, { - "val" : "neuronames:22" + "val" : "neuronames:22", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1709" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -25311,7 +28690,16 @@ }, { "val" : "TAO:0002156" }, { - "val" : "UMLS:C0006121" + "val" : "UMLS:C0006121", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1565" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Brain_Stem" + } ] + } }, { "val" : "VHOG:0001457" }, { @@ -25319,7 +28707,13 @@ }, { "val" : "ZFA:0001707" }, { - "val" : "neuronames:236" + "val" : "neuronames:236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1565" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -25399,7 +28793,13 @@ }, { "val" : "TAO:0002143" }, { - "val" : "UMLS:C0682708" + "val" : "UMLS:C0682708", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:White_Matter" + } ] + } }, { "val" : "VHOG:0001764" }, { @@ -25477,7 +28877,13 @@ }, { "val" : "EHDAA2:0000267" }, { - "val" : "FBbt:00005060" + "val" : "FBbt:00005060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85006" }, { @@ -25489,7 +28895,13 @@ }, { "val" : "TAO:0001438" }, { - "val" : "UMLS:C0333343" + "val" : "UMLS:C0333343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cavity" + } ] + } }, { "val" : "galen:BodyCavity" } ], @@ -25553,7 +28965,13 @@ }, { "val" : "TAO:0000135" }, { - "val" : "UMLS:C0028439" + "val" : "UMLS:C0028439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochord" + } ] + } }, { "val" : "VHOG:0000199" }, { @@ -25649,7 +29067,13 @@ }, { "val" : "TAO:0000155" }, { - "val" : "UMLS:C0376449" + "val" : "UMLS:C0376449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somite" + } ] + } }, { "val" : "VHOG:0000191" }, { @@ -25661,7 +29085,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:17237766" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somite" @@ -25698,7 +29128,13 @@ }, { "val" : "NCIT:C12957" }, { - "val" : "UMLS:C1516995" + "val" : "UMLS:C1516995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_System" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" }, { @@ -25763,7 +29199,13 @@ }, { "val" : "SCTID:361462002" }, { - "val" : "UMLS:C0027789" + "val" : "UMLS:C0027789", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Crest" + } ] + } }, { "val" : "VHOG:0000057" }, { @@ -25835,7 +29277,13 @@ }, { "val" : "EV:0100004" }, { - "val" : "FBbt:00001057" + "val" : "FBbt:00001057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:87657" }, { @@ -25847,7 +29295,13 @@ }, { "val" : "TAO:0001120" }, { - "val" : "UMLS:C1518271" + "val" : "UMLS:C1518271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neuroectoderm" + } ] + } }, { "val" : "VHOG:0000150" }, { @@ -25905,7 +29359,13 @@ }, { "val" : "SCTID:115976003" }, { - "val" : "UMLS:C0015282" + "val" : "UMLS:C0015282", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" } ], @@ -25968,7 +29428,13 @@ }, { "val" : "TAO:0001641" }, { - "val" : "UMLS:C0009780" + "val" : "UMLS:C0009780", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Connective_Tissue" + } ] + } }, { "val" : "VSAO:0000017" }, { @@ -26036,7 +29502,13 @@ }, { "val" : "SCTID:91727004" }, { - "val" : "UMLS:C2328219" + "val" : "UMLS:C2328219", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle_Tissue" + } ] + } }, { "val" : "Wikipedia:Muscle_tissue" }, { @@ -26114,7 +29586,13 @@ }, { "val" : "TAO:0005023" }, { - "val" : "UMLS:C0018957" + "val" : "UMLS:C0018957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hematopoietic_System" + } ] + } }, { "val" : "VHOG:0001624" }, { @@ -26230,7 +29708,13 @@ }, { "val" : "EMAPA:18425" }, { - "val" : "FBbt:00100317" + "val" : "FBbt:00100317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7146" }, { @@ -26248,7 +29732,13 @@ }, { "val" : "SCTID:134358001" }, { - "val" : "UMLS:C1285092" + "val" : "UMLS:C1285092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gland" + } ] + } }, { "val" : "Wikipedia:Gland" }, { @@ -26384,7 +29874,13 @@ "xrefs" : [ { "val" : "BIRNLEX:1011" }, { - "val" : "EMAPA:37442" + "val" : "EMAPA:37442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67552" }, { @@ -26449,7 +29945,13 @@ }, { "val" : "SCTID:384763002" }, { - "val" : "UMLS:C0445620" + "val" : "UMLS:C0445620", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Brain_Part" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -26684,7 +30186,13 @@ }, { "val" : "TE:E5.11.2.0.0.0.4" }, { - "val" : "UMLS:C1511224" + "val" : "UMLS:C1511224", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Island" + } ] + } }, { "val" : "VHOG:0000085" }, { @@ -26844,7 +30352,13 @@ }, { "val" : "TAO:0001202" }, { - "val" : "UMLS:C0231109" + "val" : "UMLS:C0231109", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Cup" + } ] + } }, { "val" : "VHOG:0000167" }, { @@ -26893,7 +30407,13 @@ }, { "val" : "TAO:0000122" }, { - "val" : "UMLS:C1517770" + "val" : "UMLS:C1517770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lens_Placodes" + } ] + } }, { "val" : "VHOG:0000166" }, { @@ -26953,7 +30473,13 @@ }, { "val" : "TAO:0000132" }, { - "val" : "UMLS:C0920623" + "val" : "UMLS:C0920623", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Plate" + } ] + } }, { "val" : "VHOG:0000068" }, { @@ -27035,7 +30561,13 @@ }, { "val" : "TAO:0000255" }, { - "val" : "UMLS:C1284009" + "val" : "UMLS:C1284009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Paraxial_Mesoderm" + } ] + } }, { "val" : "VHOG:0000114" }, { @@ -27126,7 +30658,13 @@ }, { "val" : "TAO:0000121" }, { - "val" : "UMLS:C1517749" + "val" : "UMLS:C1517749", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lateral_Mesoderm" + } ] + } }, { "val" : "VHOG:0000118" }, { @@ -27171,7 +30709,13 @@ }, { "val" : "TAO:0000028" }, { - "val" : "UMLS:C1514450" + "val" : "UMLS:C1514450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium_of_the_Heart" + } ] + } }, { "val" : "XAO:0000336" }, { @@ -27221,7 +30765,13 @@ }, { "val" : "TAO:0001080" }, { - "val" : "UMLS:C0183176" + "val" : "UMLS:C0183176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclerotome" + } ] + } }, { "val" : "VHOG:0000680" }, { @@ -27275,7 +30825,13 @@ }, { "val" : "TAO:0000137" }, { - "val" : "UMLS:C0231107" + "val" : "UMLS:C0231107", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Stalk" + } ] + } }, { "val" : "VHOG:0000223" }, { @@ -27443,7 +30999,13 @@ }, { "val" : "TAO:0000393" }, { - "val" : "UMLS:C0162415" + "val" : "UMLS:C0162415", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesenchyme" + } ] + } }, { "val" : "VHOG:0000170" }, { @@ -27582,7 +31144,13 @@ }, { "val" : "NCIT:C49334" }, { - "val" : "UMLS:C1706995" + "val" : "UMLS:C1706995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Brain_White_Matter" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -27690,7 +31258,13 @@ }, { "val" : "SCTID:91728009" }, { - "val" : "UMLS:C0027757" + "val" : "UMLS:C0027757", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_Tissue" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -27952,7 +31526,13 @@ }, { "val" : "NCIT:C34195" }, { - "val" : "UMLS:C1512940" + "val" : "UMLS:C1512940", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intraembryonic_Coelom" + } ] + } }, { "val" : "VHOG:0000316" }, { @@ -27985,7 +31565,13 @@ }, { "val" : "NCIT:C67387" }, { - "val" : "UMLS:C0927195" + "val" : "UMLS:C0927195", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stroma_Connective_Tissue" + } ] + } } ] } }, { @@ -28047,7 +31633,13 @@ }, { "val" : "TAO:0000046" }, { - "val" : "UMLS:C1518263" + "val" : "UMLS:C1518263", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Retina" + } ] + } }, { "val" : "VHOG:0000535" }, { @@ -28081,7 +31673,13 @@ }, { "val" : "EHDAA2:0003114" }, { - "val" : "FBbt:00007474" + "val" : "FBbt:00007474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -28486,7 +32084,13 @@ }, { "val" : "TAO:0000050" }, { - "val" : "UMLS:C0231106" + "val" : "UMLS:C0231106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Optic_Vesicle" + } ] + } }, { "val" : "VHOG:0000165" }, { @@ -28845,7 +32449,13 @@ }, { "val" : "TAO:0002157" }, { - "val" : "UMLS:C0011665" + "val" : "UMLS:C0011665", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Descemet_s_Membrane" + } ] + } }, { "val" : "Wikipedia:Descemet%27s_membrane" }, { @@ -28926,7 +32536,13 @@ }, { "val" : "TAO:0002155" }, { - "val" : "UMLS:C0229127" + "val" : "UMLS:C0229127", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bowman_s_Membrane" + } ] + } }, { "val" : "Wikipedia:Bowman%27s_membrane" }, { @@ -29017,7 +32633,13 @@ }, { "val" : "TAO:0000010" }, { - "val" : "UMLS:C0007226" + "val" : "UMLS:C0007226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiovascular_System" + } ] + } }, { "val" : "VHOG:0000302" }, { @@ -29143,7 +32765,13 @@ }, { "val" : "SCTID:362060003" }, { - "val" : "UMLS:C1267406" + "val" : "UMLS:C1267406", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venous_System" + } ] + } }, { "val" : "VHOG:0000277" } ], @@ -29175,7 +32803,13 @@ }, { "val" : "TAO:0005257" }, { - "val" : "UMLS:C1706972" + "val" : "UMLS:C1706972", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel_Endothelium" + } ] + } }, { "val" : "ZFA:0005257" } ], @@ -29213,7 +32847,13 @@ }, { "val" : "NCIT:C34131" }, { - "val" : "UMLS:C1516779" + "val" : "UMLS:C1516779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conceptus" + } ] + } }, { "val" : "Wikipedia:Conceptus" } ], @@ -29327,7 +32967,13 @@ }, { "val" : "BTO:0001403" }, { - "val" : "FBbt:00005317" + "val" : "FBbt:00005317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:293108" }, { @@ -29341,9 +32987,21 @@ }, { "val" : "NCIT:C34058" }, { - "val" : "UMLS:C0017199" - }, { - "val" : "UMLS:C1284022" + "val" : "UMLS:C0017199", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrula" + } ] + } + }, { + "val" : "UMLS:C1284022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trilaminar_Embryonic_Disc" + } ] + } }, { "val" : "Wikipedia:Gastrula" }, { @@ -29459,7 +33117,13 @@ }, { "val" : "TAO:0002171" }, { - "val" : "UMLS:C0014261" + "val" : "UMLS:C0014261", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_Endothelium" + } ] + } }, { "val" : "VHOG:0001217" }, { @@ -29568,7 +33232,13 @@ "val" : "joint" } ], "xrefs" : [ { - "val" : "FBbt:00005811" + "val" : "FBbt:00005811", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -29605,7 +33275,13 @@ "xrefs" : [ "FMA:71131" ] } ], "xrefs" : [ { - "val" : "FBbt:00100315" + "val" : "FBbt:00100315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:71131" } ], @@ -29658,7 +33334,13 @@ }, { "val" : "SCTID:361463007" }, { - "val" : "UMLS:C0814992" + "val" : "UMLS:C0814992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Groove" + } ] + } }, { "val" : "Wikipedia:Neural_groove" }, { @@ -29695,7 +33377,13 @@ }, { "val" : "SCTID:361461009" }, { - "val" : "UMLS:C0814993" + "val" : "UMLS:C0814993", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Fold" + } ] + } }, { "val" : "Wikipedia:Neural_fold" }, { @@ -29831,7 +33519,13 @@ }, { "val" : "CARO:0001000" }, { - "val" : "FBbt:00007060" + "val" : "FBbt:00007060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:83115" } ], @@ -29859,7 +33553,13 @@ "val" : "dorsal region organ" } ], "xrefs" : [ { - "val" : "EMAPA:37274" + "val" : "EMAPA:37274", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0001901" } ], @@ -29884,7 +33584,13 @@ "xrefs" : [ "MA:0000516" ] } ], "xrefs" : [ { - "val" : "EMAPA:37270" + "val" : "EMAPA:37270", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000516" } ], @@ -29909,7 +33615,13 @@ "xrefs" : [ "MA:0000557" ] } ], "xrefs" : [ { - "val" : "EMAPA:37273" + "val" : "EMAPA:37273", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000557" } ], @@ -29934,7 +33646,13 @@ "xrefs" : [ "MA:0000563" ] } ], "xrefs" : [ { - "val" : "EMAPA:37271" + "val" : "EMAPA:37271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000563" } ], @@ -30112,7 +33830,13 @@ "val" : "light-sensitive tissue" } ], "xrefs" : [ { - "val" : "FBbt:00004200" + "val" : "FBbt:00004200", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -30162,7 +33886,13 @@ }, { "val" : "EHDAA2:0003125" }, { - "val" : "FBbt:00007006" + "val" : "FBbt:00007006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:292313" }, { @@ -30495,13 +34225,25 @@ }, { "val" : "SCTID:68989006" }, { - "val" : "UMLS:C0004799" + "val" : "UMLS:C0004799", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Basement_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "http://palaeos.com/metazoa/porifera/homoscleromorpha.html" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "basement membrane of epithelium" @@ -30608,7 +34350,13 @@ }, { "val" : "SCTID:361725000" }, { - "val" : "UMLS:C0222645" + "val" : "UMLS:C0222645", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Axial_Skeleton" + } ] + } }, { "val" : "VSAO:0000056" }, { @@ -30707,7 +34455,13 @@ }, { "val" : "SCTID:362296008" }, { - "val" : "UMLS:C0027750" + "val" : "UMLS:C0027750", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Myelinated_Nerve_Fiber" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -30748,7 +34502,13 @@ }, { "val" : "SCTID:46920005" }, { - "val" : "UMLS:C0501409" + "val" : "UMLS:C0501409", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Unmyelinated_Nerve_Fiber" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -30959,7 +34719,13 @@ }, { "val" : "NCIT:C34231" }, { - "val" : "UMLS:C1518429" + "val" : "UMLS:C1518429", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Plate" + } ] + } }, { "val" : "VHOG:0001212" } ], @@ -31000,7 +34766,13 @@ }, { "val" : "NCIT:C34232" }, { - "val" : "UMLS:C1518430" + "val" : "UMLS:C1518430", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Process" + } ] + } }, { "val" : "VHOG:0001213" } ], @@ -31034,7 +34806,13 @@ "xrefs" : [ { "val" : "BTO:0002085" }, { - "val" : "EMAPA:37529" + "val" : "EMAPA:37529", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:58071" }, { @@ -31044,7 +34822,13 @@ }, { "val" : "SCTID:280540004" }, { - "val" : "UMLS:C0459556" + "val" : "UMLS:C0459556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Chamber_of_the_Eye" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -31089,7 +34873,13 @@ "xrefs" : [ { "val" : "BIRNLEX:20" }, { - "val" : "EMAPA:37441" + "val" : "EMAPA:37441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:280556" }, { @@ -31313,7 +35103,13 @@ }, { "val" : "SCTID:40118003" }, { - "val" : "UMLS:C0221909" + "val" : "UMLS:C0221909", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Squamous_epithelium" } ], @@ -31366,7 +35162,13 @@ }, { "val" : "NCIT:C34022" }, { - "val" : "UMLS:C1515977" + "val" : "UMLS:C1515977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Surface" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -31485,7 +35287,13 @@ }, { "val" : "SCTID:360394002" }, { - "val" : "UMLS:C1514442" + "val" : "UMLS:C1514442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordial_Gut" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -32108,7 +35916,13 @@ }, { "val" : "EHDAA2:0003170" }, { - "val" : "FBbt:00005426" + "val" : "FBbt:00005426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "Wikipedia:Anlage_(biology)" } ], @@ -32224,7 +36038,13 @@ }, { "val" : "NCIT:C33854" }, { - "val" : "UMLS:C0489903" + "val" : "UMLS:C0489903", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_System" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -32280,7 +36100,13 @@ }, { "val" : "SCTID:361355005" }, { - "val" : "UMLS:C0460004" + "val" : "UMLS:C0460004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Head_and_Neck" + } ] + } }, { "val" : "WikipediaCategory:Head_and_neck" }, { @@ -32584,7 +36410,13 @@ "xrefs" : [ { "val" : "CARO:0010000" }, { - "val" : "FBbt:00100313" + "val" : "FBbt:00100313", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -33086,7 +36918,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007330" + "val" : "FBbt:00007330", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67509" }, { @@ -33199,7 +37037,13 @@ "val" : "main body segment" } ], "xrefs" : [ { - "val" : "FBbt:00057001" + "val" : "FBbt:00057001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -33285,7 +37129,13 @@ }, { "val" : "NCIT:C32450" }, { - "val" : "UMLS:C1511770" + "val" : "UMLS:C1511770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Dense_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Dense_connective_tissue" } ], @@ -33322,7 +37172,13 @@ }, { "val" : "NCIT:C33007" }, { - "val" : "UMLS:C1253917" + "val" : "UMLS:C1253917", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Loose_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Loose_connective_tissue" } ], @@ -33413,7 +37269,13 @@ "xrefs" : [ "MP:0005194" ] } ], "xrefs" : [ { - "val" : "EMAPA:37417" + "val" : "EMAPA:37417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "SCTID:280656002" } ], @@ -33461,7 +37323,13 @@ "val" : "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "coelom" @@ -33525,7 +37393,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7955" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7955", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1177/0192623311409597" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "tunica fibrosa of eyeball" @@ -33759,7 +37633,13 @@ "xrefs" : [ { "val" : "AEO:0000093" }, { - "val" : "FBbt:00007278" + "val" : "FBbt:00007278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -33824,7 +37704,13 @@ "xrefs" : [ "MA:0002449" ] } ], "xrefs" : [ { - "val" : "EMAPA:37597" + "val" : "EMAPA:37597", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002449" } ], @@ -34223,7 +38109,13 @@ "xrefs" : [ { "val" : "CARO:0020000" }, { - "val" : "FBbt:00007276" + "val" : "FBbt:00007276", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -34458,7 +38350,13 @@ "comments" : [ "It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however, most visceral muscles in arthropods are actually striated." ], "synonyms" : [ { "pred" : "hasExactSynonym", - "val" : "visceral muscle" + "val" : "visceral muscle", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "BTO:0002780" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -36119,7 +40017,13 @@ "meta" : { "definition" : { "val" : "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -36135,7 +40039,13 @@ "meta" : { "definition" : { "val" : "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -36459,7 +40369,7 @@ } }, { "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym", - "lbl" : "has_narrow_synonym", + "lbl" : "has narrow synonym", "type" : "PROPERTY", "propertyType" : "ANNOTATION", "meta" : { @@ -36598,6 +40508,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000008", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000333" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000030", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000030", "pred" : "is_a", @@ -36606,6 +40520,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000030", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", "obj" : "http://purl.obolibrary.org/obo/CL_0000133" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000031", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000031", "pred" : "is_a", @@ -36614,22 +40532,18 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000031", "pred" : "http://purl.obolibrary.org/obo/RO_0002162", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_7742" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0011115" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", - "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0017145" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000037", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000037", "pred" : "is_a", @@ -36796,6 +40710,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000076", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000066" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000076", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000077", "pred" : "is_a", @@ -37156,6 +41074,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000219" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000333", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", @@ -37296,6 +41218,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000540", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0019226" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000541", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000541", "pred" : "is_a", @@ -37712,6 +41638,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000679", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0061535" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000680", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000680", "pred" : "is_a", @@ -38214,6 +42144,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0002672", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000048" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0002672", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0002672", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", @@ -38236,6 +42170,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0007004", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", @@ -38330,10 +42268,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0011026", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", @@ -38700,7 +42634,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0032991" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005581", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "pred" : "http://purl.obolibrary.org/obo/RO_0002160", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005587", @@ -39142,6 +43076,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008016", "pred" : "http://purl.obolibrary.org/obo/RO_0002211", "obj" : "http://purl.obolibrary.org/obo/GO_0060047" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0008150", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", + "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -40605,7 +44543,7 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0071953", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", - "obj" : "http://purl.obolibrary.org/obo/GO_0031012" + "obj" : "http://purl.obolibrary.org/obo/GO_0140149" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0071971", "pred" : "is_a", @@ -40926,6 +44864,14 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0140143", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/GO_0140139" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0140149", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/GO_0030312" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0140149", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", + "obj" : "http://purl.obolibrary.org/obo/GO_0140151" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0140151", "pred" : "is_a", @@ -41042,6 +44988,14 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_117571", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_117570" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_119089", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6231" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33317" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_131567", "pred" : "is_a", @@ -41066,10 +45020,22 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6236" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33154" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "pred" : "is_a", @@ -41102,6 +45068,10 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33213", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6072" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33317", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33213" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33511", "pred" : "is_a", @@ -41154,10 +45124,34 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_554915", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2759" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_55879", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_55885", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6243" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6072", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6231", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6236", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_119089" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6237", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_55885" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6243", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_55879" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_7711", "pred" : "is_a", @@ -41290,6 +45284,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0001579", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0001591", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0000052" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0001690", "pred" : "is_a", @@ -41370,6 +45368,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002226", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001873" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0002254", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001591" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002266", "pred" : "is_a", @@ -49522,6 +53524,13 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0001981" } ] + }, { + "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000076", + "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], + "restrictions" : [ { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002254" + } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000081", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -52210,6 +56219,13 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" } ] + }, { + "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", + "allValuesFromEdges" : [ { + "sub" : "http://purl.obolibrary.org/obo/GO_0005581", + "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062", "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], diff --git a/subsets/eye_upper_slim.obo b/subsets/eye_upper_slim.obo index 37ec70605..d48854275 100644 --- a/subsets/eye_upper_slim.obo +++ b/subsets/eye_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2025-12-17/subsets/eye_upper_slim.owl +data-version: cl/releases/2026-03-17/subsets/eye_upper_slim.owl idspace: dc http://purl.org/dc/elements/1.1/ idspace: foaf http://xmlns.com/foaf/0.1/ idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# @@ -7,7 +7,7 @@ idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: terms http://purl.org/dc/terms/ ontology: cl/subsets/eye_upper_slim -property_value: owl:versionInfo "2025-12-17" xsd:string +property_value: owl:versionInfo "2026-03-17" xsd:string [Term] id: BFO:0000002 @@ -120,6 +120,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009010 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000030" xsd:string {name="glioblast on CELLxGENE CellGuide"} @@ -136,6 +137,7 @@ synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 xref: ZFA:0009011 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002162 NCBITaxon:7742 ! in taxon Vertebrata property_value: skos:prefLabel "neuroblast (sensu Vertebrata)" xsd:string @@ -144,21 +146,18 @@ property_value: skos:prefLabel "neuroblast (sensu Vertebrata)" xsd:string id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] -comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset -synonym: "animal stem cell" EXACT [] +synonym: "animal stem cell" NARROW [] xref: CALOHA:TS-2086 xref: FMA:63368 xref: ZFA:0005957 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa relationship: RO:0002215 GO:0017145 ! capable of stem cell division property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000034" xsd:string {name="stem cell on CELLxGENE CellGuide"} @@ -185,6 +184,7 @@ xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 xref: ZFA:0009014 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell @@ -425,13 +425,18 @@ property_value: skos:prefLabel "columnar/cuboidal epithelial cell" xsd:string [Term] id: CL:0000076 name: squamous epithelial cell +def: "An epithelial cell that has a flattened morphology." [] subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: CALOHA:TS-1249 xref: ZFA:0009039 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell +intersection_of: CL:0000066 ! epithelial cell +intersection_of: RO:0000053 PATO:0002254 ! has characteristic flattened +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: skos:prefLabel "squamous epithelial cell" xsd:string +property_value: terms:date "2025-12-16T15:56:39Z" xsd:dateTime [Term] id: CL:0000077 @@ -755,6 +760,7 @@ name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset subset: general_cell_types_upper_slim +subset: human_reference_atlas subset: human_subset subset: mouse_subset synonym: "muscle fiber" EXACT [] @@ -772,6 +778,7 @@ is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell relationship: RO:0002202 CL:0000056 ! develops from myoblast property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI +property_value: RO:0002175 NCBITaxon:9606 property_value: skos:prefLabel "muscle cell" xsd:string [Term] @@ -1037,6 +1044,7 @@ subset: mouse_subset xref: FMA:86667 xref: ZFA:0007086 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell @@ -1252,6 +1260,7 @@ subset: mouse_subset xref: BTO:0003217 xref: FMA:83377 xref: ZFA:0009249 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell @@ -1653,6 +1662,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009291 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell @@ -1778,6 +1788,7 @@ intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0001791 ! has soma location inner nuclear layer of retina relationship: RO:0002100 UBERON:0001791 ! has soma location inner nuclear layer of retina property_value: RO:0002175 NCBITaxon:9606 +property_value: seeAlso https://celltype.info/project/544/dataset/1157 {name="reference transcriptomic data on Cell Annotation Platform"} property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000748" xsd:string {name="retinal bipolar neuron on CELLxGENE CellGuide"} property_value: terms:description "The retinal bipolar neuron is an integral part of the eye, specifically located within the retina. They are secondary neurons in the visual pathway and primarily serve to transmit information from photoreceptor cells, which respond to light, to retinal ganglion cells, which carry the signal to the brain. As such, these cells play a pivotal role in our ability to interpret and perceive visual information.\nThe structure of retinal bipolar neurons is unique and significant to their function. They are termed \"bipolar\" due to their morphology, having two poles: a single dendrite on one end and an axon on the other. The dendrite end connects to photoreceptor cells (rods or cones), while the axon end synapses with retinal ganglion cells. In the center of the dendrite and axon lies the cell body, which houses the cell's nucleus and other vital organelles.\nAt the functional level, retinal bipolar neurons can be categorized into ON and OFF types based on their response to light. 'ON' bipolar cells are depolarized (electrical potential across the cell membrane decreases) under light conditions, thereby increasing their rate of neurotransmitter release onto the downstream ganglion cells. In contrast, 'OFF' bipolar cells are hyperpolarized (electrical potential increases) in light conditions, decreasing their rate of neurotransmitter release. This dual system allows for a fine-tuned response and the ability to perceive differences in light intensity and contrast, thus creating a nuanced and detailed visual world.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" xsd:string {xref="DOI:10.1016/j.preteyeres.2008.03.003", xref="DOI:10.1016/j.ydbio.2021.09.005", xref="DOI:10.1017/S0952523810000209", xref="DOI:10.1038/nrn3783", xref="DOI:10.1126/science.201028"} @@ -2293,6 +2304,7 @@ subset: eye_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset +synonym: "RPE" EXACT OMO:0003000 [PMID:35835183] xref: BTO:0004910 xref: FMA:75802 is_a: CL:0000066 ! epithelial cell @@ -2317,6 +2329,7 @@ subset: human_subset subset: mouse_subset is_a: BFO:0000002 is_a: CL:0000048 ! multi fate stem cell +is_a: CL:0000255 ! eukaryotic cell relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell property_value: skos:prefLabel "retinal progenitor cell" xsd:string property_value: terms:contributor https://orcid.org/0000-0003-1980-3228 @@ -2345,6 +2358,7 @@ subset: human_subset subset: mouse_subset xref: ZFA:0007084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: BFO:0000002 +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell @@ -2476,7 +2490,6 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset is_a: BFO:0000002 -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002202 CL:0000034 ! develops from stem cell @@ -2642,6 +2655,7 @@ is_a: GO:0140096 ! catalytic activity, acting on a protein is_a: GO:0140101 ! catalytic activity, acting on a tRNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0000262 @@ -2980,6 +2994,7 @@ subset: goslim_yeast synonym: "molecular function" EXACT [] disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process +property_value: IAO:0000116 "This is the same as GO molecular function" xsd:string [Term] id: GO:0003824 @@ -3016,6 +3031,9 @@ synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 +union_of: GO:0032991 ! protein-containing complex +union_of: GO:0044423 ! virion component +union_of: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0008150 ! biological_process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI @@ -3064,7 +3082,8 @@ namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa +relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa +relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0005587 @@ -3906,6 +3925,7 @@ synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process +relationship: BFO:0000051 GO:0003674 ! has part molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI creation_date: 2012-09-19T15:05:24Z @@ -4458,10 +4478,10 @@ subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" -xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016746 @@ -4478,6 +4498,7 @@ xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurin xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" is_a: GO:0016740 ! transferase activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016755 @@ -4487,6 +4508,7 @@ def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) synonym: "transferase activity, transferring amino-acyl groups" EXACT [] xref: EC:2.3.2.- is_a: GO:0016746 ! acyltransferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0017145 @@ -4703,6 +4725,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] @@ -4711,6 +4734,7 @@ is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] @@ -4718,6 +4742,7 @@ id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:18391171] +subset: gocheck_do_not_annotate synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly @@ -4725,6 +4750,7 @@ is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI [Term] id: GO:0030054 @@ -5063,6 +5089,7 @@ is_a: GO:0005575 ! cellular_component disjoint_from: GO:0044423 ! virion component disjoint_from: GO:0110165 ! cellular anatomical structure relationship: BFO:0000051 PR:000000001 ! has part protein +property_value: IAO:0000116 "This is not covalently bonded, which conflicts with changes to the parent definition." xsd:string [Term] id: GO:0034101 @@ -5190,12 +5217,13 @@ def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which mel xref: Wikipedia:Melanosome is_a: GO:0048770 ! pigment granule relationship: BFO:0000050 CL:0000148 ! part of melanocyte +property_value: RO:0002161 NCBITaxon:6237 [Term] id: GO:0042592 name: homeostatic process namespace: biological_process -def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] +def: "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." [PMID:26265027] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse @@ -5206,6 +5234,7 @@ synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological_process +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31175" xsd:anyURI [Term] id: GO:0042644 @@ -5272,6 +5301,7 @@ id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon @@ -5284,6 +5314,7 @@ synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: BFO:0000050 CL:0000000 ! part of cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: skos:prefLabel "cell projection" xsd:string [Term] @@ -6435,11 +6466,12 @@ creation_date: 2010-10-04T01:51:47Z id: GO:0071953 name: elastic fiber namespace: cellular_component -def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620] +def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, PMID:12082143, PMID:16893474, PMID:20236620] synonym: "elastic fibre" EXACT [GOC:mah] synonym: "elastin fiber" EXACT [GOC:BHF] is_a: GO:0099512 ! supramolecular fiber -relationship: BFO:0000050 GO:0031012 ! part of extracellular matrix +relationship: BFO:0000050 GO:0140149 ! part of non-collagenous component of interstitial matrix +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31135" xsd:anyURI property_value: skos:prefLabel "elastic fiber" xsd:string creation_date: 2010-10-11T11:44:57Z @@ -6574,15 +6606,16 @@ def: "A collagen trimer that forms networks." [PMID:21421911] is_a: BFO:0000004 is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer -intersection_of: BFO:0000050 GO:0098645 ! part of collagen network -relationship: BFO:0000050 GO:0098645 ! part of collagen network +intersection_of: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens +relationship: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens [Term] id: GO:0098643 -name: fibrillar collagen +name: fibrillar collagen complex namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175] synonym: "banded collagen fibril" EXACT [] +synonym: "fibrillar collagen" EXACT [] is_a: GO:0098644 ! complex of collagen trimers relationship: BFO:0000050 GO:0140152 ! part of collagenous component of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI @@ -6603,10 +6636,12 @@ property_value: skos:prefLabel "complex of collagen trimers" xsd:string [Term] id: GO:0098645 -name: collagen network +name: complex of network-forming collagens namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] +synonym: "collagen network" EXACT [] is_a: GO:0098644 ! complex of collagen trimers +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30938" xsd:anyURI [Term] id: GO:0098793 @@ -6742,6 +6777,8 @@ subset: goslim_pir synonym: "cellular anatomical entity" EXACT [] is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure +property_value: IAO:0000116 "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." xsd:string +property_value: IAO:0000116 "Overlaps with some cellular components from GO" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28978" xsd:anyURI @@ -6871,6 +6908,17 @@ relationship: BFO:0000050 GO:0140139 ! part of solid phase of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29472" xsd:anyURI creation_date: 2025-03-20T11:47:59Z +[Term] +id: GO:0140149 +name: non-collagenous component of interstitial matrix +namespace: cellular_component +def: "The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin." [PMID:21123617, PMID:25701227, PMID:33605520, PMID:39223427] +is_a: GO:0030312 ! external encapsulating structure +relationship: BFO:0000050 GO:0140151 ! part of solid phase of interstitial matrix +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29491" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30146" xsd:anyURI +creation_date: 2025-03-20T13:08:49Z + [Term] id: GO:0140151 name: solid phase of interstitial matrix @@ -6896,7 +6944,7 @@ id: GO:0140154 name: chicken-wire-like collagen network namespace: cellular_component def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942] -is_a: GO:0098645 ! collagen network +is_a: GO:0098645 ! complex of network-forming collagens relationship: BFO:0000050 GO:0140143 ! part of collagenous component of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI @@ -7057,6 +7105,21 @@ xref: GC_ID:1 is_a: NCBITaxon:117570 ! Teleostomi property_value: skos:prefLabel "Euteleostomi" xsd:string +[Term] +id: NCBITaxon:119089 +name: Chromadorea +namespace: ncbi_taxonomy +synonym: "Adenophorea" RELATED synonym [] +xref: GC_ID:1 +is_a: NCBITaxon:6231 ! Nematoda + +[Term] +id: NCBITaxon:1206794 +name: Ecdysozoa +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:33317 ! Protostomia + [Term] id: NCBITaxon:131567 name: cellular organisms @@ -7149,6 +7212,20 @@ xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2759 ! Eukaryota +[Term] +id: NCBITaxon:2301116 +name: Rhabditina +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:6236 ! Rhabditida + +[Term] +id: NCBITaxon:2301119 +name: Rhabditomorpha +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:2301116 ! Rhabditina + [Term] id: NCBITaxon:2759 name: Eukaryota @@ -7165,6 +7242,22 @@ xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: skos:prefLabel "Eukaryota" xsd:string +[Term] +id: NCBITaxon:28009 +name: Choanoflagellata +namespace: ncbi_taxonomy +synonym: "Choanoflagellatea" RELATED synonym [] +synonym: "choanoflagellates" EXACT genbank_common_name [] +synonym: "choanoflagellates" RELATED blast_name [] +synonym: "Choanoflagellida" RELATED synonym [] +synonym: "Choanomonada" RELATED synonym [] +synonym: "Choanozoa" RELATED synonym [] +xref: GC_ID:1 +xref: PMID:27765632 +is_a: NCBITaxon:33154 ! Opisthokonta +disjoint_from: NCBITaxon:33208 ! Metazoa +disjoint_from: NCBITaxon:4751 ! Fungi + [Term] id: NCBITaxon:314146 name: Euarchontoglires @@ -7249,6 +7342,14 @@ xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa property_value: skos:prefLabel "Bilateria" xsd:string +[Term] +id: NCBITaxon:33317 +name: Protostomia +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:33213 ! Bilateria +disjoint_from: NCBITaxon:33511 ! Deuterostomia + [Term] id: NCBITaxon:33511 name: Deuterostomia @@ -7368,6 +7469,20 @@ xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota +[Term] +id: NCBITaxon:55879 +name: Rhabditoidea +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:2301119 ! Rhabditomorpha + +[Term] +id: NCBITaxon:55885 +name: Peloderinae +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:6243 ! Rhabditidae + [Term] id: NCBITaxon:6072 name: Eumetazoa @@ -7376,6 +7491,41 @@ xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: skos:prefLabel "Eumetazoa" xsd:string +[Term] +id: NCBITaxon:6231 +name: Nematoda +namespace: ncbi_taxonomy +synonym: "Nemata" RELATED synonym [] +synonym: "nematode" EXACT OMO:0003003 [] +synonym: "nematodes" EXACT genbank_common_name [] +synonym: "nematodes" RELATED blast_name [] +synonym: "roundworm" EXACT OMO:0003003 [] +synonym: "roundworms" EXACT OMO:0003003 [] +xref: GC_ID:1 +is_a: NCBITaxon:1206794 ! Ecdysozoa + +[Term] +id: NCBITaxon:6236 +name: Rhabditida +namespace: ncbi_taxonomy +synonym: "Strongylida" RELATED synonym [] +xref: GC_ID:1 +is_a: NCBITaxon:119089 ! Chromadorea + +[Term] +id: NCBITaxon:6237 +name: Caenorhabditis +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:55885 ! Peloderinae + +[Term] +id: NCBITaxon:6243 +name: Rhabditidae +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:55879 ! Rhabditoidea + [Term] id: NCBITaxon:7711 name: Chordata @@ -7706,6 +7856,14 @@ subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality +[Term] +id: PATO:0001591 +name: curvature +namespace: quality +def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] +subset: attribute_slim +is_a: PATO:0000052 ! shape + [Term] id: PATO:0001690 name: contractile @@ -7882,6 +8040,18 @@ is_a: PATO:0001873 ! cylindrical property_value: terms:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-07-13T04:22:30Z +[Term] +id: PATO:0002254 +name: flattened +namespace: quality +def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] +comment: Becoming flat but not necessarily completely flat. +subset: value_slim +synonym: "compressed" RELATED [] +is_a: PATO:0001591 ! curvature +property_value: terms:contributor https://orcid.org/0000-0002-2061-091X +creation_date: 2010-08-16T03:59:34Z + [Term] id: PATO:0002266 name: 3-D shape @@ -17948,7 +18118,7 @@ xref: NCIT:C32339 xref: NIF_Subcellular:sao7547390221 is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: RO:0002473 GO:0005581 ! composed primarily of collagen trimer -relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen +relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen complex property_value: seeAlso UBERON:0007377 property_value: skos:prefLabel "collection of collagen fibrils" xsd:string diff --git a/subsets/eye_upper_slim.owl b/subsets/eye_upper_slim.owl index 80d50f337..d9a4c8213 100644 --- a/subsets/eye_upper_slim.owl +++ b/subsets/eye_upper_slim.owl @@ -14,8 +14,8 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - - 2025-12-17 + + 2026-03-17 @@ -245,7 +245,6 @@ WHERE { An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has narrow synonym - has_narrow_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/19 @@ -2856,6 +2855,7 @@ Each of these 3 primitives can be composed to yield a cross-product of different + @@ -2912,6 +2912,7 @@ When glioblast multiplication is dysregulated, it can lead to harmful manifestat + @@ -2960,14 +2961,7 @@ When glioblast multiplication is dysregulated, it can lead to harmful manifestat - - - - - - - @@ -2984,13 +2978,12 @@ Stem cells have numerous potential applications in medicine, including the treat CALOHA:TS-2086 FMA:63368 ZFA:0005957 - animal stem cell + animal stem cell - This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. stem cell https://cellxgene.cziscience.com/cellguide/CL_0000034 stem cell @@ -3097,6 +3090,7 @@ Stem cells have numerous potential applications in medicine, including the treat + @@ -3886,7 +3880,26 @@ Blood vessel endothelial cells are sensitive to various stimuli, including shear + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -4817,6 +4830,7 @@ In addition to melanin production, melanocytes also engage in a variety of other A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -4830,6 +4844,7 @@ In addition to melanin production, melanocytes also engage in a variety of other + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -5622,6 +5637,7 @@ The spatial distribution of these cell types throughout the retina also contribu + @@ -6215,6 +6231,7 @@ Functionally, smooth muscle myoblasts and the mature muscle cells they generate + @@ -7753,6 +7770,7 @@ Moreover, Mueller cells are also responsible for maintaining the structural inte + @@ -8183,6 +8201,7 @@ At the functional level, retinal bipolar neurons can be categorized into ON and retinal bipolar neuron + https://cellxgene.cziscience.com/cellguide/CL_0000748 @@ -8234,6 +8253,12 @@ At the functional level, retinal bipolar neurons can be categorized into ON and + + + + + reference transcriptomic data on Cell Annotation Platform + @@ -9779,6 +9804,7 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest 2011-03-06T03:37:09Z BTO:0004910 FMA:75802 + RPE @@ -9807,6 +9833,13 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest DOI:10.3389/fphar.2021.727870/full https://www.sciencedirect.com/topics/chemistry/retinal-pigment + + + + RPE + PMID:35835183 + + @@ -9821,6 +9854,7 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest + @@ -9901,6 +9935,7 @@ Beyond this, RPE cells take part in the phagocytosis process, where they digest + @@ -10169,7 +10204,7 @@ In the field of regenerative medicine, mesenchymal cells, particularly mesenchym - + Any photoreceptor cell that is part of some camera-type eye. camera type eye photoreceptor cell @@ -10177,14 +10212,14 @@ In the field of regenerative medicine, mesenchymal cells, particularly mesenchym camera-type eye photoreceptor cell camera-type eye photoreceptor cell - + - + https://github.com/obophenotype/cell-ontology/issues/2245 @@ -10273,7 +10308,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -10775,6 +10809,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. https://github.com/geneontology/go-ontology/issues/22192 https://github.com/geneontology/go-ontology/issues/25493 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.12 MetaCyc:PEPTIDYLTRANSFERASE-RXN Reactome:R-HSA-156912 @@ -11720,6 +11755,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. + This is the same as GO molecular function molecular function molecular_function GO:0003674 @@ -11782,6 +11818,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + @@ -11901,10 +11946,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component @@ -14010,6 +14061,12 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. https://github.com/geneontology/go-ontology/issues/24968 2012-09-19T15:05:24Z @@ -14241,6 +14298,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. @@ -14289,6 +14370,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + @@ -14359,6 +14450,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + @@ -14429,6 +14530,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + @@ -14465,6 +14576,70 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. @@ -15349,10 +15524,10 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + https://github.com/geneontology/go-ontology/issues/30193 EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 - Reactome:R-HSA-5333607 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function @@ -15387,12 +15562,6 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 - - - - Reactome:R-HSA-5333607 - GSSeH combines with bGalNAc derivative to form GSSebGalNac - @@ -15414,6 +15583,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 @@ -15464,6 +15634,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function @@ -16084,12 +16255,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 https://github.com/geneontology/go-ontology/issues/26279 cell projection organisation biological_process cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 + cell projection organization @@ -16139,10 +16312,12 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 formation of a cell surface projection biological_process cell projection biogenesis GO:0030031 + cell projection assembly @@ -17045,6 +17220,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + This is not covalently bonded, which conflicts with changes to the parent definition. macromolecular complex macromolecule complex protein containing complex @@ -17476,13 +17652,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. + Wikipedia:Melanosome cellular_component GO:0042470 @@ -17502,7 +17695,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - Any biological process involved in the maintenance of an internal steady state. + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + https://github.com/geneontology/go-ontology/issues/31175 homeostasis activation of homeostatic process inhibition of homeostatic process @@ -17519,9 +17713,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - Any biological process involved in the maintenance of an internal steady state. - GOC:jl - ISBN:0395825172 + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + PMID:26265027 @@ -17629,6 +17822,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + @@ -17737,11 +17940,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 cell process cellular process cellular projection cellular_component GO:0042995 + @@ -20851,10 +21056,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. + https://github.com/geneontology/go-ontology/issues/31135 2010-10-11T11:44:57Z elastic fibre elastin fiber @@ -20868,7 +21074,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. GOC:BHF - GOC:mah + PMID:12082143 + PMID:16893474 PMID:20236620 @@ -21320,9 +21527,10 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://github.com/geneontology/go-ontology/issues/29474 https://github.com/geneontology/go-ontology/issues/30146 banded collagen fibril + fibrillar collagen cellular_component GO:0098643 - fibrillar collagen + fibrillar collagen complex fibrillar collagen @@ -21387,9 +21595,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A supramolecular complex that consists of collagen triple helices associated to form a network. + https://github.com/geneontology/go-ontology/issues/30938 + collagen network cellular_component GO:0098645 - collagen network + complex of network-forming collagens @@ -21805,6 +22015,9 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes. + Overlaps with some cellular components from GO https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 https://github.com/geneontology/go-ontology/issues/28978 @@ -22151,6 +22364,36 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin. + https://github.com/geneontology/go-ontology/issues/29491 + https://github.com/geneontology/go-ontology/issues/30146 + 2025-03-20T13:08:49Z + cellular_component + GO:0140149 + non-collagenous component of interstitial matrix + + + + + The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin. + PMID:21123617 + PMID:25701227 + PMID:33605520 + PMID:39223427 + + + + @@ -22648,6 +22891,37 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + GC_ID:1 + ncbi_taxonomy + Adenophorea + NCBITaxon:119089 + Chromadorea + + + + + Adenophorea + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:1206794 + Ecdysozoa + + + + @@ -22872,6 +23146,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:2301116 + Rhabditina + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:2301119 + Rhabditomorpha + + + + @@ -22929,6 +23227,63 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + GC_ID:1 + PMID:27765632 + choanoflagellates + ncbi_taxonomy + Choanoflagellatea + Choanoflagellida + Choanomonada + Choanozoa + choanoflagellates + NCBITaxon:28009 + Choanoflagellata + + + + + choanoflagellates + + + + + + Choanoflagellatea + + + + + + Choanoflagellida + + + + + + Choanomonada + + + + + + Choanozoa + + + + + + choanoflagellates + + + + + @@ -23119,6 +23474,19 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:33317 + Protostomia + + + + @@ -23375,6 +23743,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:55879 + Rhabditoidea + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:55885 + Peloderinae + + + + @@ -23388,6 +23780,103 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + GC_ID:1 + nematode + nematodes + roundworm + roundworms + ncbi_taxonomy + Nemata + nematodes + NCBITaxon:6231 + Nematoda + + + + + nematode + + + + + + nematodes + + + + + + roundworm + + + + + + roundworms + + + + + + Nemata + + + + + + nematodes + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + Strongylida + NCBITaxon:6236 + Rhabditida + + + + + Strongylida + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:6237 + Caenorhabditis + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:6243 + Rhabditidae + + + + @@ -24142,6 +24631,25 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + quality + PATO:0001591 + + curvature + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + WordNet:WordNet + + + + @@ -24526,6 +25034,29 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + + 2010-08-16T03:59:34Z + quality + compressed + PATO:0002254 + + Becoming flat but not necessarily completely flat. + flattened + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + PATOC:CVS + + + + @@ -25988,7 +26519,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -26026,14 +26557,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou camera-type eye camera-type eye - + - + definitional @@ -27381,7 +27912,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube) EHDAA2:0001968 @@ -27404,7 +27935,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou external ectoderm http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png - + @@ -27417,7 +27948,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 @@ -27495,7 +28026,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -27506,14 +28037,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou membrane organ membrane organ - + - + FMA-def @@ -28282,7 +28813,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -28324,14 +28855,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou gastrula stage gastrula stage - + - + BILS @@ -28913,15 +29444,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - - + + A fluid that is composed of blood plasma and erythrocytes. @@ -28960,34 +29491,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou blood blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -30820,7 +31351,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. AAO:0000137 BILA:0000036 @@ -30855,14 +31386,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -30902,7 +31433,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. AAO:0000139 BILA:0000038 @@ -30937,14 +31468,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -30985,7 +31516,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The middle germ layer of the embryo, between the endoderm and ectoderm. AAO:0000304 @@ -31025,14 +31556,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + - + Bgee:AN @@ -31215,7 +31746,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -31279,14 +31810,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou cranial nerve II cranial nerve II - + - + EHDAA2 @@ -31396,7 +31927,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -31461,14 +31992,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb - + - + MA @@ -31510,7 +32041,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -31535,7 +32066,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. requires review for applicability to invertebrate structures, e.g. synganglion @@ -31595,11 +32126,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://cdn.humanatlas.io/digital-objects/ref-organ/brain-female/v1.4/assets/3d-allen-f-brain.glb https://cdn.humanatlas.io/digital-objects/ref-organ/brain-male/v1.4/assets/3d-allen-m-brain.glb - + - + @@ -31612,13 +32143,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + FMA - + Bgee:AN @@ -31870,9 +32401,9 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - + + + @@ -31897,7 +32428,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -31951,44 +32482,44 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou cornea http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + - + MA - + MA - + FMA-isa - + definitional @@ -32165,10 +32696,10 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - - + + + + The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. @@ -32216,44 +32747,44 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou retina http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png - + - + - + - + - + FMA - + FMA - + FMA - + EHDAA2 @@ -32308,8 +32839,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -32341,24 +32872,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eye eye - + - + - + PMID:21062451 - + PMID:21062451 @@ -32758,7 +33289,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -32809,14 +33340,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -32876,7 +33407,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. @@ -32921,7 +33452,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou central nervous system central nervous system - + @@ -32935,7 +33466,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Bgee:AN @@ -33667,7 +34198,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -33692,14 +34223,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -34080,7 +34611,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A tube extending from the mouth to the anus. @@ -34118,14 +34649,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou digestive tract digestive tract - + - + NCBIBook:NBK10107 @@ -34186,7 +34717,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. BTO:0000654 @@ -34209,7 +34740,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ciliary muscle http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png - + @@ -34228,7 +34759,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + FMA @@ -34517,7 +35048,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -34562,14 +35093,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eyelid https://upload.wikimedia.org/wikipedia/commons/8/84/Eye_makeup.jpg - + - + multiple @@ -34828,7 +35359,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -34867,14 +35398,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou iris iris - + - + XAO @@ -34928,7 +35459,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -34977,14 +35508,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou corneal epithelium http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + ISBN:0781772214 @@ -35072,15 +35603,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + - + @@ -35121,34 +35652,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou sclera http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + FMA - + ZFA - + ISBN:0781772214 @@ -35191,7 +35722,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -35229,14 +35760,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ciliary body http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + ISBN:0781772214 @@ -35274,14 +35805,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + @@ -35342,24 +35873,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou optic choroid http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + MA - + Wikipedia @@ -35542,15 +36073,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - - - + + + A double layer covering the ciliary body that produces aqueous humor. BTO:0001770 @@ -35570,15 +36101,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ciliary epithelium ciliary epithelium - + - + - + @@ -35591,19 +36122,19 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + MA - + MP - + Wikipedia @@ -35719,7 +36250,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -35776,14 +36307,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou pigmented layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + - + Wikipedia @@ -35859,7 +36390,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -35890,14 +36421,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou photoreceptor layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + - + ZFA @@ -36388,7 +36919,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -36443,7 +36974,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou ganglionic layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + @@ -36456,7 +36987,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + FMA @@ -36510,7 +37041,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -36563,14 +37094,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou nerve fiber layer of retina - + - + FMA @@ -37260,7 +37791,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -37292,14 +37823,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou anterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png - + - + cjm @@ -37342,7 +37873,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -37372,14 +37903,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou posterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + cjm @@ -37416,9 +37947,9 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - + + + @@ -37465,15 +37996,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou conjunctiva http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png - + - + - + @@ -37486,19 +38017,19 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + cjm - + MA - + ISBN:0781772214 @@ -37562,7 +38093,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The most anterior region of the brain including both the telencephalon and diencephalon. @@ -37604,14 +38135,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou forebrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -37651,14 +38182,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. developmental relationships need revised @@ -37704,24 +38235,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG - + - + - + definitional - + Bgee:AN @@ -37773,14 +38304,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + The division of the forebrain that develops from the foremost primary cerebral vesicle. DiE @@ -37837,24 +38368,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou diencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + - + definitional - + definitional @@ -38204,7 +38735,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. MTg @@ -38244,14 +38775,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain tegmentum http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png - + - + ZFA @@ -38578,8 +39109,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -38592,7 +39123,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -38646,34 +39177,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -39079,7 +39610,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. @@ -39122,14 +39653,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou hindbrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + Bgee:AN @@ -39771,7 +40302,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Vasculature that is part of the eye region. FMA:74743 @@ -39793,14 +40324,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://cdn.humanatlas.io/digital-objects/ref-organ/blood-vasculature-female/v1.3/assets/3d-vh-f-blood-vasculature.glb https://cdn.humanatlas.io/digital-objects/ref-organ/blood-vasculature-male/v1.3/assets/3d-vh-m-blood-vasculature.glb - + - + ISBN:0781772214 @@ -40077,15 +40608,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - - + + Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). TODO - add superclass to unify with VNC? @@ -40141,34 +40672,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou https://cdn.humanatlas.io/digital-objects/ref-organ/spinal-cord-female/v1.1/assets/3d-vh-f-spinal-cord.glb https://cdn.humanatlas.io/digital-objects/ref-organ/spinal-cord-male/v1.1/assets/3d-vh-m-spinal-cord.glb - + - + - + - + ZFA - + definitional - + definitional @@ -40499,7 +41030,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -40535,14 +41066,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou coelemic cavity lumen coelemic cavity lumen - + - + definitional @@ -40638,8 +41169,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -40689,11 +41220,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -40712,13 +41243,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA - + EHDAA2 @@ -40759,7 +41290,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. mesodermal cluster @@ -40797,7 +41328,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -40810,7 +41341,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA @@ -40929,16 +41460,16 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - + + + - + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. AAO:0010578 BTO:0001764 @@ -40971,45 +41502,45 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + BTO - + PMID:11523831 - + PMID:11523831 @@ -41370,8 +41901,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + Anatomical system that is involved in the production of hematopoietic cells. @@ -41412,24 +41943,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou hematopoietic system hematopoietic system - + - + - + FMA - + definitional @@ -41460,14 +41991,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - - + + @@ -41493,11 +42024,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou iris epithelium iris epithelium - + - + @@ -41510,13 +42041,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + MA - + MP @@ -41751,7 +42282,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. Do not merge with neurogenic placode ectodermal placode @@ -41768,7 +42299,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou cranial placode cranial placode - + @@ -41781,7 +42312,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + PMID:11523831 PMID:22512454 @@ -41981,7 +42512,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -41994,7 +42525,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. consider adding class for organizer. Consider adding separate class for isthmus as a structure AAO:0011064 @@ -42023,24 +42554,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain-hindbrain boundary midbrain-hindbrain boundary - + - + - + ZFA - + ZFA @@ -42153,7 +42684,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -42172,7 +42703,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. AAO:0011086 EFO:0001982 @@ -42195,14 +42726,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presomitic mesoderm presomitic mesoderm - + - + Bgee:AN @@ -42371,7 +42902,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -42407,7 +42938,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eye primordium eye primordium - + @@ -42420,7 +42951,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + PMID:16496288 XAO @@ -42470,8 +43001,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -42499,24 +43030,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou optic cup optic cup - + - + - + ZFA - + ZFA @@ -42572,7 +43103,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -42610,7 +43141,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou lens placode http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png - + @@ -42623,7 +43154,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA @@ -42662,8 +43193,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. AAO:0011072 BTO:0001765 @@ -42692,24 +43223,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + Wikipedia - + Bgee:AN @@ -42791,7 +43322,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. AAO:0010568 EFO:0003515 @@ -42817,7 +43348,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -42830,7 +43361,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Bgee:AN @@ -42907,7 +43438,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -42946,7 +43477,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -42959,7 +43490,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 VHOG @@ -43010,15 +43541,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. AAO:0011044 @@ -43035,15 +43566,15 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou heart primordium heart primordium - + - + - + @@ -43056,19 +43587,19 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA - + ZFA - + XAO @@ -43097,8 +43628,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. AAO:0010571 AEO:0000212 @@ -43122,11 +43653,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -43145,13 +43676,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + VHOG:0000680 - + ZFA @@ -43465,7 +43996,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Mesenchyme that is part of a developing camera-type eye. TODO - change mesenchyme relationships to precursor_of EHDAA2:0000485 @@ -43477,14 +44008,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eye mesenchyme eye mesenchyme - + - + EHDAA2 @@ -44293,7 +44824,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults EHDAA:251 @@ -44308,14 +44839,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou intraembryonic coelom intraembryonic coelom - + - + Wikipedia @@ -44381,7 +44912,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -44399,7 +44930,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The part of the retina that contains neurons and photoreceptor cells[GO]. AAO:0011095 @@ -44430,14 +44961,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou retinal neural layer retinal neural layer - + - + Bgee:AN @@ -44737,7 +45268,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. consider merging with 'ventricular zone'; note that the MA class probably does not belong here, as this is an embryonic structure ependymal layer @@ -44754,7 +45285,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou neural tube ventricular layer neural tube ventricular layer - + @@ -44767,7 +45298,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + NCBIBook:NBK10047 @@ -45176,9 +45707,9 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - - + + + @@ -45210,34 +45741,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou optic vesicle http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png - + - + - + - + ZFA - + GO-def - + ZFA @@ -45333,8 +45864,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. XAO:0004185 first heart field @@ -45346,24 +45877,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou primary heart field primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -45416,7 +45947,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + An epithelial tube that will give rise to the mature heart. AAO:0010411 EFO:0003526 @@ -45435,14 +45966,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou heart tube heart tube - + - + ZFA-modified @@ -45509,12 +46040,12 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + @@ -45530,14 +46061,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eye muscle eye muscle - + - + MA @@ -45720,7 +46251,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. @@ -45750,14 +46281,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou Descemet's membrane https://github.com/obophenotype/uberon/issues/15 - + - + Cline et al @@ -46597,7 +47128,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. AAO:0011129 TAO:0001890 @@ -46611,14 +47142,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou skeletal element skeletal element - + - + VSAO @@ -46646,7 +47177,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -46679,14 +47210,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou articular system articular system - + - + FMA @@ -47523,7 +48054,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. EFO:0003492 EHDAA2:0000732 @@ -47544,14 +48075,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou head mesenchyme head mesenchyme - + - + EHDAA2 @@ -47609,7 +48140,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -47625,14 +48156,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou trunk mesenchyme trunk mesenchyme - + - + EHDAA2 @@ -47655,7 +48186,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. BTO:0000758 CALOHA:TS-0607 @@ -47675,14 +48206,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou myelencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -48150,7 +48681,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. TAO:0002188 ZFA:0001688 @@ -48158,7 +48689,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou corneal primordium corneal primordium - + @@ -48177,7 +48708,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + ZFA @@ -48200,7 +48731,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. EHDAA2:0001512 EHDAA:424 @@ -48218,14 +48749,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou primitive heart tube primitive heart tube - + - + ZFA @@ -48408,7 +48939,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -48418,7 +48949,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou developing mesenchymal condensation developing mesenchymal condensation - + @@ -48437,7 +48968,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + AEO-modified-relation @@ -48495,8 +49026,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -48512,11 +49043,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou UBERON:0005908 conjunctival sac - + - + @@ -48529,13 +49060,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + FMA - + HPO:pr @@ -48820,7 +49351,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -48843,14 +49374,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou future diencephalon future diencephalon - + - + EHDAA2 @@ -49026,7 +49557,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -49050,14 +49581,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou future spinal cord future spinal cord - + - + EHDAA2 @@ -49094,7 +49625,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB EHDAA2:0001278 @@ -49108,7 +49639,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou notochordal plate notochordal plate - + @@ -49121,7 +49652,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 @@ -49150,7 +49681,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -49167,14 +49698,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou notochordal process notochordal process - + - + EHDAA2 @@ -50199,8 +50730,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + @@ -50226,24 +50757,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presumptive hindbrain presumptive hindbrain - + - + - + XAO-abduced - + cjm @@ -50294,7 +50825,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -50313,14 +50844,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presumptive midbrain hindbrain boundary presumptive midbrain hindbrain boundary - + - + ZFA @@ -50467,7 +50998,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -50493,7 +51024,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presumptive paraxial mesoderm presumptive paraxial mesoderm - + @@ -50509,7 +51040,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + https://github.com/obophenotype/uberon/issues/1277 @@ -50583,12 +51114,12 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + A neural decussation that is part of a diencephalon. FMA:62446 diencephalon decussation @@ -50596,7 +51127,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou decussation of diencephalon decussation of diencephalon - + @@ -50609,7 +51140,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Obol @@ -50685,7 +51216,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -50693,7 +51224,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou dense mesenchyme tissue dense mesenchyme tissue - + @@ -50706,7 +51237,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + AEO @@ -50772,7 +51303,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -50792,14 +51323,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou layer of synovial tissue layer of synovial tissue - + - + BTO @@ -51107,7 +51638,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + An axon tract that is part of a brain. the NIFSTD class 'nerve tract' is classified under 'regional part of brain', so it may seem like it belongs here, but actually includes spinal cord tracts FMA:83848 @@ -51117,14 +51648,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou tract of brain tract of brain - + - + cjm @@ -51259,7 +51790,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -51276,14 +51807,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou vascular system vascular system - + - + MA @@ -51407,7 +51938,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -51423,14 +51954,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou entire embryonic mesenchyme entire embryonic mesenchyme - + - + EHDAA2 @@ -51527,7 +52058,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -51543,14 +52074,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain hindbrain boundary neural plate midbrain hindbrain boundary neural plate - + - + ZFA @@ -51584,14 +52115,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + @@ -51616,24 +52147,24 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou presumptive midbrain presumptive midbrain - + - + - + ZFA - + ZFA @@ -51679,7 +52210,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme @@ -51687,14 +52218,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou trunk paraxial mesoderm trunk paraxial mesoderm - + - + EHDAA2 @@ -51789,7 +52320,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -51799,14 +52330,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou anterior lateral plate mesoderm anterior lateral plate mesoderm - + - + ZFA @@ -51862,14 +52393,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2:0001315 EHDAA:1122 UBERON:0009920 optic neural crest optic neural crest - + @@ -51882,7 +52413,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 @@ -52022,7 +52553,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -52045,14 +52576,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou eyeball of camera-type eye eyeball of camera-type eye - + - + FMA @@ -52093,8 +52624,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. DHBA:12322 EFO:0003567 @@ -52108,11 +52639,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain basal plate midbrain basal plate - + - + @@ -52125,13 +52656,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + EHDAA2 - + ZFA @@ -52159,7 +52690,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Portion of neural tube that gives rise to the midbrain. we follow ZFA in temporally dividing midbrain NT from presumptive midbrain, but in future this may be collapsed TAO:0007039 @@ -52168,14 +52699,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou midbrain neural tube midbrain neural tube - + - + ZFA @@ -52203,7 +52734,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Developing anatomical structure that develops into the eyeball and associated structures. TAO:0002201 ZFA:0001678 @@ -52212,14 +52743,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou immature eye immature eye - + - + definitional @@ -52484,7 +53015,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -52494,14 +53025,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou microcirculatory vessel microcirculatory vessel - + - + ZFA @@ -52526,8 +53057,8 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. FMA:23879 SCTID:129140006 @@ -52539,11 +53070,11 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou subdivision of skeleton subdivision of skeleton - + - + @@ -52556,13 +53087,13 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + UBERONREF:0000003 - + VSAO @@ -52656,7 +53187,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -52667,7 +53198,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton postcranial axial skeletal system - + @@ -52680,7 +53211,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + cjm @@ -52800,7 +53331,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + AAO:0010038 EMAPA:18808 FMA:49150 @@ -52810,14 +53341,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou intra-ocular muscle intra-ocular muscle - + - + EMAPA @@ -53203,7 +53734,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -53251,7 +53782,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou anterior uvea anterior uvea - + @@ -53264,7 +53795,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + MP @@ -54143,7 +54674,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + @@ -54166,7 +54697,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou entire extraembryonic component entire extraembryonic component - + @@ -54179,7 +54710,7 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + AEO @@ -55055,14 +55586,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + - + @@ -55256,14 +55787,14 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou - + - + definitional - + @@ -55461,6 +55992,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -55555,6 +56114,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -55569,6 +56156,40 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -55701,6 +56322,30 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + @@ -55883,6 +56528,34 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -55897,6 +56570,62 @@ Additionally, ciliary muscle cells play a role in draining the eye's aqueou + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/subsets/eye_upper_slim.tsv b/subsets/eye_upper_slim.tsv index 036f1ccea..a00cb6c4d 100644 --- a/subsets/eye_upper_slim.tsv +++ b/subsets/eye_upper_slim.tsv @@ -424,9 +424,9 @@ http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer -http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen +http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers -http://purl.obolibrary.org/obo/GO_0098645 collagen network +http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling @@ -449,6 +449,7 @@ http://purl.obolibrary.org/obo/GO_0140101 catalytic activity, acting on a tRNA http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis http://purl.obolibrary.org/obo/GO_0140139 solid phase of basement membrane http://purl.obolibrary.org/obo/GO_0140143 collagenous component of basement membrane +http://purl.obolibrary.org/obo/GO_0140149 non-collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0140151 solid phase of interstitial matrix http://purl.obolibrary.org/obo/GO_0140152 collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0140154 chicken-wire-like collagen network @@ -465,13 +466,18 @@ http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_10090 Mus musculus http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi +http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea +http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria +http://purl.obolibrary.org/obo/NCBITaxon_2301116 Rhabditina +http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota +http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda @@ -480,6 +486,7 @@ http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria +http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_34346 Schizosaccharomycetales @@ -493,7 +500,13 @@ http://purl.obolibrary.org/obo/NCBITaxon_4894 Schizosaccharomycetaceae http://purl.obolibrary.org/obo/NCBITaxon_4895 Schizosaccharomyces http://purl.obolibrary.org/obo/NCBITaxon_4896 Schizosaccharomyces pombe http://purl.obolibrary.org/obo/NCBITaxon_554915 Amoebozoa +http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea +http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa +http://purl.obolibrary.org/obo/NCBITaxon_6231 Nematoda +http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida +http://purl.obolibrary.org/obo/NCBITaxon_6237 Caenorhabditis +http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata @@ -527,6 +540,7 @@ http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0001579 contractility +http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0001873 cylindrical @@ -545,6 +559,7 @@ http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0002124 laminar http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance http://purl.obolibrary.org/obo/PATO_0002226 subcylindrical +http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002309 fiber shaped diff --git a/subsets/general_cell_types_upper_slim.json b/subsets/general_cell_types_upper_slim.json index 577a04942..a718314a3 100644 --- a/subsets/general_cell_types_upper_slim.json +++ b/subsets/general_cell_types_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2025-12-17" + "val" : "2026-03-17" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2025-12-17/subsets/general_cell_types_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2026-03-17/subsets/general_cell_types_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -40,7 +40,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { - "val" : "FBbt:00007002" + "val" : "FBbt:00007002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:68646" }, { @@ -56,7 +62,13 @@ }, { "val" : "XAO:0003012" }, { - "val" : "ZFA:0009000" + "val" : "ZFA:0009000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -74,7 +86,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009002" + "val" : "ZFA:0009002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -90,10 +108,9 @@ "val" : "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, - "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { - "pred" : "hasExactSynonym", + "pred" : "hasNarrowSynonym", "val" : "animal stem cell" } ], "xrefs" : [ { @@ -101,7 +118,13 @@ }, { "val" : "FMA:63368" }, { - "val" : "ZFA:0005957" + "val" : "ZFA:0005957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -111,7 +134,13 @@ "val" : "Stem cells are a unique type of cell that has the remarkable ability to divide and develop into many different types of cells in the body. These cells are undifferentiated, meaning they haven't yet developed into a specific cell type, and they can renew themselves through cell division. As a result, stem cells have the potential to replace damaged or diseased cells in the body, making them a valuable tool in medicine and research.\nThere are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos and can develop into any type of cell in the body. Adult stem cells, on the other hand, are found in various tissues and organs throughout the body and can only develop into certain types of cells.\nStem cells have numerous potential applications in medicine, including the treatment of various diseases and the repair of damaged tissues. For example, they could be used to replace damaged heart tissue after a heart attack or to repair spinal cord injuries. Stem cells also have potential uses in drug development and disease research, as they can be used to model diseases and test potential therapies in vitro.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stem cell" @@ -153,7 +182,13 @@ }, { "val" : "VHOG:0001485" }, { - "val" : "ZFA:0009014" + "val" : "ZFA:0009014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -163,7 +198,13 @@ "val" : "Hematopoietic stem cells (HSCs) are multipotent cells, capable of differentiating into a wide variety of specialized blood cells. During embryonic development hematopoietic stem cells emerge from the hemogenic endothelium, a specialized subset of endothelial cells with hematopoietic potential. HSCs can be found in several organs, in particular in bone marrow, as well as peripheral blood and umbilical cord blood.\nThese stem cells have a distinctive ability to self-renew, and to differentiate into all lymphoid and myeloid cell types that together form the blood and immune systems including erythrocytes (red blood cells), leukocytes (white blood cells), and platelets. Their primary function is to ensure the continuous replenishment of the blood and immune system throughout an individual's lifespan.\nIn response to various signals, hematopoietic stem cells can either remain dormant or actively divide and differentiate. Under normal conditions, the majority of these stem cells exist in a quiescent (inactive) state, making them somewhat resistant to chemotherapy or radiation therapy in the treatment of various diseases such as leukemia. However, when the body encounters stress such as infection, bleeding, or disease, hematopoietic stem cells can rapidly become active in order to replenish the affected cells and maintain homeostasis.\nFurthermore, hematopoietic stem cells are extremely important in the field of regenerative medicine and transplantation. Regarded as lifesaving in the field of oncology, they are often extracted, purified, and reinfused back into the same (autologous transplantation) or different (allogeneic transplantation) individuals to reestablish a healthy, functioning hematopoietic and immune system after high-dose chemotherapy or to replace dysfunctional bone marrow. Understanding and manipulating the behavior of these stem cells has immense potential in treating various blood disorders, autoimmune diseases, and cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "hematopoietic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "hematopoietic stem cell" @@ -203,14 +244,26 @@ "xrefs" : [ { "val" : "BTO:0004911" }, { - "val" : "ZFA:0009015" + "val" : "ZFA:0009015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Erythroid progenitor cells play a key role in the hematopoietic system, specifically in the process of erythropoiesis – the production of red blood cells (erythrocytes). Found within the bone marrow, these cells are dedicated precursors to erythrocytes, and ensue in the hematopoietic lineage from multipotent progenitors. They represent a transitional cell type that bridges the gap between the early-stage erythroid precursors and the maturing red blood cell population.\nThe earliest committed erythroid progenitor cell is thought to be the burst-forming unit-erythroid (BFU-E) cell, which after several cell divisions gives rise to another erythroid progenitor, the colony-forming unit-erythroid (CFU-E) cell. \nErythroid progenitor cells are primarily responsible for responding to the demand for new red blood cells during conditions of physiological stress like infection, blood loss, or illness. This responsive behavior is regulated by a glycoprotein hormone known as erythropoietin, which is produced by the kidneys. Erythropoietin interacts with the receptors on the erythroid progenitor cells, prompting them to proliferate and differentiate into erythroblasts. The erythroblasts then further mature, eventually producing new, functional red cells.\nThe role of erythroid progenitor cells extends beyond their main function of erythrocyte production, as they also participate in maintaining the balance of iron in the body. Upon erythroid differentiation, they increase their uptake of transferrin-bound iron for hemoglobin synthesis, a vital component of red blood cells which allows them to transport oxygen. A deficiency or excess of erythroid progenitor cells can lead to extensive health issues such as anemia or polycythemia respectively, emphasizing their crucial role in human health.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythroid progenitor cell" @@ -228,7 +281,13 @@ "comments" : [ "Originally this term had some plant germ line cell children." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { - "val" : "ZFA:0009016" + "val" : "ZFA:0009016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -261,7 +320,13 @@ "xrefs" : [ { "val" : "FMA:84789" }, { - "val" : "ZFA:0009020" + "val" : "ZFA:0009020", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -317,7 +382,13 @@ "xrefs" : [ { "val" : "BTO:0004730" }, { - "val" : "ZFA:0009021" + "val" : "ZFA:0009021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -327,7 +398,13 @@ "val" : "The common myeloid progenitor (CMP) is a multipotent cell that serves as a crucial intermediary within the overall framework of hematopoietic cell differentiation, which is the process of blood cell production. This part of the hematopoiesis process leads to the formation of myeloid lineage cells, which includes granulocytes (neutrophils, eosinophils, and basophils), monocytes, erythrocytes (red blood cells), and megakaryocytes (platelet-forming cells). \nThe primary function of common myeloid progenitors is differentiation and proliferation into various types of mature blood cells, thereby providing a critical contribution to maintaining homeostasis within the body's immune and circulatory systems. Single-cell analyses have shown that the CMP cell population is heterogeneous with at least two distinct subpopulations, characterized by different cell surface markers and likely already committed to downstream differentiation into either the granulocyte/macrophage lineage or the megakaryocyte/erythrocyte lineage-restricted progenitor. \nThe destiny of a CMP is influenced by numerous cytokines and growth factors in its environment that promote differentiation along specific lineages. For example, IL-3 and GM-CSF stimulate the production of eosinophils, which are essential for the body’s defense against allergens and help fight fungal and parasitic infections. \nBy being able to differentiate into a wide range of different immune cells, common myeloid progenitors play a crucial role in the body's ability to respond to injuries, infections, and other physiological challenges.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "common myeloid progenitor on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "common myeloid progenitor" @@ -367,7 +444,13 @@ "val" : "megakaryocyte/erythroid progenitor cell" } ], "xrefs" : [ { - "val" : "ZFA:0009022" + "val" : "ZFA:0009022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -377,7 +460,13 @@ "val" : "The megakaryocyte-erythroid progenitor (MEP) cell belongs to the multipotent hematopoietic progenitor cells, which can give rise to multiple different cell types. They are found in the bone marrow, the primary organ where new blood cells are generated. MEPs are specially programmed to develop into two distinct blood cell lineages, namely megakaryocytes, which go on to produce platelets for blood clotting, and the erythroid lineage which consists of red blood cells responsible for oxygen transport in the body.\nThe MEP cells are the result of a decision-making process within the hematopoietic stem cell population. Hematopoietic stem cell can differentiate into multiple types of progenitor cells, including myeloid progenitor cells. A further subdivision within this myeloid lineage generates the MEP cells. Therefore, these megakaryocyte-erythroid progenitors represent a key juncture between hematopoietic stem cells and mature blood cell types in the myeloid lineage.\nMegakaryocyte-erythroid progenitor cells play a crucial role in the homeostasis of some of the most crucial constituents of blood. The megakaryocytes produced from these bipotent progenitor cells contribute to hemostasis by producing platelets - small anucleated fragments that are pivotal for blood clotting and preventing bleeding. Similarly, the erythroid lineage from MEP cells gives rise to erythrocytes, which harbor hemoglobin, the molecule that transports oxygen from lungs to every nook and corner of the body. An imbalance or malfunction in MEP function thus can significantly impact human health, leading to diseases like thrombocytopenia or anemia.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte-erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "megakaryocyte-erythroid progenitor cell" @@ -402,7 +491,13 @@ }, { "val" : "MESH:D039901" }, { - "val" : "ZFA:0009024" + "val" : "ZFA:0009024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -424,13 +519,25 @@ }, { "val" : "CALOHA:TS-0650" }, { - "val" : "FBbt:00005083" + "val" : "FBbt:00005083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:70335" }, { "val" : "VHOG:0001529" }, { - "val" : "ZFA:0009025" + "val" : "ZFA:0009025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -459,7 +566,13 @@ }, { "val" : "VHOG:0001482" }, { - "val" : "ZFA:0009026" + "val" : "ZFA:0009026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -490,13 +603,25 @@ }, { "val" : "CARO:0000077" }, { - "val" : "FBbt:00000124" + "val" : "FBbt:00000124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:66768" }, { "val" : "WBbt:0003672" }, { - "val" : "ZFA:0009034" + "val" : "ZFA:0009034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -520,7 +645,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009036" + "val" : "ZFA:0009036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -530,7 +661,13 @@ "val" : "Blood vessel endothelial cells, also known as vascular endothelial cells, form the delicate inner lining of the complex circulatory system, including arteries and veins. These cells form a single, continuous monolayer inside every blood vessel, acting as a crucial biomolecular barrier between the blood, and the rest of the body tissues. They perform various fundamental biological functions, ranging from maintenance of vessel integrity to blood clotting regulation. Additionally, they control the transportation of fluids, molecules, and blood particulate matter from and into the bloodstream.\nOne of the primary functions of blood vessel endothelial cells is to maintain vascular homeostasis - a stable environment within the blood vessels. They accomplish this through several methods: they control vasomotor tone, i.e. the degree of contraction and dilation of blood vessels, by secreting vasoactive substances such as nitric oxide and endothelin; mediate responses to inflammatory stimuli; and they also regulate angiogenesis, the process of new blood vessel formations. Blood vessel endothelial cells play a significant role in preventing blood clot formation by generating a slick, non-thrombogenic surface that disallows platelets or coagulant proteins from adhering to it.\nBlood vessel endothelial cells are sensitive to various stimuli, including shear stress caused by blood flow, and they can respond by altering their morphology, function, and gene expression. This ability to adapt enables blood vessels to remodel and ensure the adequate delivery of nutrients and oxygen to all tissues, regardless of physiological demand variations. Conversely, endothelial dysfunction, often associated with a reduction in the bioavailability of endothelium-derived nitric oxide, can lead to the development of pathological conditions such as atherosclerosis, hypertension, diabetes mellitus, and even aging-related diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "blood vessel endothelial cell" @@ -541,13 +678,25 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "definition" : { + "val" : "An epithelial cell that has a flattened morphology." + }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" }, { - "val" : "ZFA:0009039" + "val" : "ZFA:0009039", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/date", + "val" : "2025-12-16T15:56:39Z" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "squamous epithelial cell" } ] @@ -570,7 +719,13 @@ "xrefs" : [ { "val" : "FMA:66773" }, { - "val" : "ZFA:0009040" + "val" : "ZFA:0009040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -580,7 +735,13 @@ "val" : "Mesothelial cells are crucial components of the mesothelium, a protective layer that lines the body's internal cavities, including pleural cavity (around the lungs), the pericardial cavity (around the heart), and the peritoneal cavity (within the abdomen). Derived from the embryonic mesoderm layer, these cells exhibit a squamous-like epithelial morphology, usually appearing as a single layer of flat, pavement-like cells in their healthy state.\nMesothelial cells play a vital role in various physiological processes, such as intraperitoneal immunity, fibrinolysis, tissue repair, and tumor suppression. Their primary function is to provide a slippery, non-adhesive and protective surface to reduce friction and eases the movements of the organs within the pleural, pericardial, and peritoneal cavities, and they participate in the transport and movement of fluid and various molecules across the so-called serosal cavities. \nThese cells have adaptive capabilities that facilitate their role in many pathological processes. In response to injury or inflammation, mesothelial cells can undergo morphological and functional changes, such as mesothelial-mesenchymal transitions, aiding in wound healing and tissue repair. Dysfunctions of mesothelial cells, however, can lead to serious health conditions, including adhesions, fibrosis, and malignancies such as peritoneal and pleural mesotheliomas.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -598,7 +759,13 @@ }, { "val" : "MESH:D001773" }, { - "val" : "ZFA:0009044" + "val" : "ZFA:0009044", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -627,7 +794,13 @@ }, { "val" : "FMA:66772" }, { - "val" : "ZFA:0009065" + "val" : "ZFA:0009065", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -652,7 +825,13 @@ "val" : "neurectoderm cell" } ], "xrefs" : [ { - "val" : "ZFA:0009080" + "val" : "ZFA:0009080", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -724,14 +903,26 @@ }, { "val" : "FMA:70546" }, { - "val" : "ZFA:0009081" + "val" : "ZFA:0009081", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. These cells originate mainly from the mesoderm of the embryo, which forms connective tissues, muscle, and the circulatory and urinary systems. However, in adults, MSCs are found in multiple tissues, including bone marrow, adipose tissue, the umbilical cord, and dental tissues. \nThe primary function of MSCs is to maintain and repair the tissues in which they are found. When damage occurs, the MSCs are able to migrate to the site of injury, where they aid in regenerating the damaged tissue by differentiating into the required cell type and by secreting growth factors that enhance tissue repair and reduce inflammation. Furthermore, MSCs can also act as immunomodulators, suppressing immune reactions and reducing inflammation, both locally and systemically.\nApart from their role in tissue maintenance and repair, MSCs are integral to the field of regenerative medicine and are being investigated for their therapeutic potential in various clinical settings. Owing to their multipotent nature, immunomodulatory activity, and the relative ease of isolation, these cells can be engineered and translated into therapies to treat a variety of diseases, including bone and cartilage defects, liver diseases, heart disorders, and autoimmune diseases, amongst others. They have also been used as vectors for anticancer agents and in cell and gene therapy applications.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val" : "https://github.com/obophenotype/cell-ontology/issues/474" @@ -760,7 +951,13 @@ "xrefs" : [ { "val" : "VHOG:0001678" }, { - "val" : "ZFA:0009090" + "val" : "ZFA:0009090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -792,7 +989,13 @@ }, { "val" : "VHOG:0001679" }, { - "val" : "ZFA:0009091" + "val" : "ZFA:0009091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -802,7 +1005,13 @@ "val" : "Melanocytes are specialized cells prevalently found in the skin, but also present in the hair follicles, eyes, inner ear, bones, heart, and brain. Their primary function is the synthesis of melanin, a pigment responsible for coloration of skin, hair, and eyes. The presence and distribution of this pigment play a crucial role in the body's defense mechanism against harmful ultraviolet radiation.\nIn addition to melanin production, melanocytes also engage in a variety of other biological functions. They play a fundamental role in the immune response, owing to their ability to present antigens to T cells. Furthermore, they contribute to the maintenance of the skin's homeostasis by regulating processes such as extracellular matrix remodeling and cytokine production. A balance in melanocyte function is pivotal, as dysfunctions often result in dermatological disorders. For instance, the loss of melanocytes or reduction in their function may lead to hypopigmentation conditions such as vitiligo, whereas an abnormal increase could result in hyperpigmentation disorders or melanoma, a dangerous type of skin cancer.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000148" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000148", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "melanocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -856,7 +1065,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -871,15 +1080,30 @@ }, { "val" : "CALOHA:TS-2032" }, { - "val" : "FBbt:00005074" + "val" : "FBbt:00005074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67328" }, { "val" : "WBbt:0003675" }, { - "val" : "ZFA:0009114" + "val" : "ZFA:0009114", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle cell" }, { @@ -898,7 +1122,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009128" + "val" : "ZFA:0009128", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -921,7 +1151,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-0995" }, { - "val" : "ZFA:0009131" + "val" : "ZFA:0009131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -935,7 +1171,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009136" + "val" : "ZFA:0009136", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -959,7 +1201,13 @@ "xrefs" : [ { "val" : "FMA:72549" }, { - "val" : "ZFA:0009137" + "val" : "ZFA:0009137", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -986,14 +1234,26 @@ "xrefs" : [ { "val" : "FMA:72554" }, { - "val" : "ZFA:0009138" + "val" : "ZFA:0009138", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesodermal cells are pluripotent and the most abundant in the human body. They contribute to the development of several structures such as the skeletal muscles, bones, heart and blood vessels, kidneys, gonads, connective tissues, and certain layers of the skin. Hence, the mesoderm is often regarded as an active and diverse layer due to its role in forming many bodily structures. \nIn embryonic development, these cells are instrumental, contributing to the body's structures through a carefully coordinated sequence of morphogenetic movements. This process forms the complex multicellular architecture of tissues and organs from a simple ball of cells. Without the function of mesodermal cells, the body's integral structures and systems would cease to form correctly, leading to developmental disorders such as axial mesodermal dysplasia complex\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesodermal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesodermal cell" @@ -1016,7 +1276,13 @@ "xrefs" : [ { "val" : "FMA:72555" }, { - "val" : "ZFA:0009139" + "val" : "ZFA:0009139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1055,7 +1321,13 @@ "val" : "Erythrocytes, also known as red blood cells, are a type of specialized cell that make up the largest percentage of cells in the human body. Erythrocytes are biconcave in shape and lack nuclei and organelles, allowing them to carry oxygen and carbon dioxide through the bloodstream more efficiently. The main function of erythrocytes is to transport oxygen from the lungs to the body's tissues and organs, and to transport carbon dioxide from the body's tissues to the lungs, where it can be exhaled out of the body. Hemoglobin, a protein located inside erythrocytes, is responsible for binding to oxygen. \nErythrocytes are produced in the bone marrow and have a lifespan of approximately 120 days before they are broken down and recycled by the body. Erythrocytes are regulated by the hormone erythropoietin, which is produced by the kidneys and liver in response to low oxygen levels in the body, thereby stimulating erythrocyte production .\nIn addition to their role in oxygen transport, erythrocytes also play a key role in regulating the body's pH levels. Without erythrocytes, oxygen would not be able to be transported efficiently throughout the body and tissues would not receive the necessary oxygen to function properly. Overall, erythrocytes are essential for maintaining the health and homeostasis of the body.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythrocyte on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythrocyte" @@ -1125,7 +1397,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009164" + "val" : "ZFA:0009164", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1145,7 +1423,13 @@ "xrefs" : [ { "val" : "FMA:86667" }, { - "val" : "ZFA:0007086" + "val" : "ZFA:0007086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1163,7 +1447,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009166" + "val" : "ZFA:0009166", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1181,7 +1471,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009176" + "val" : "ZFA:0009176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1236,7 +1532,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009190" + "val" : "ZFA:0009190", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1254,7 +1556,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009193" + "val" : "ZFA:0009193", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1276,7 +1584,13 @@ }, { "val" : "FMA:83624" }, { - "val" : "ZFA:0009226" + "val" : "ZFA:0009226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1286,7 +1600,13 @@ "val" : "Stromal cells constitute a significant portion of the structural cellular milieu (stroma) that supports the function of parenchymal (functional) cells within an organ. The stroma is the connective, supportive framework of biological tissues with various functions depending on the specific organ and cell type. Stromal cells, derived from the mesenchymal lineage, play crucial roles in creating, maintaining, and repairing the tissue microenvironment in virtually all mammalian organs, making these cells indispensable to biological function.\nAdditionally, stromal cells secrete growth factors, cytokines, and extracellular matrix (ECM) molecules to constitute an interactive cellular network and ensure an optimal environment for the functional cells. Beyond mere structural support, these cells are instrumental in wound healing, inflammation, and maintaining tissue integrity. They may also influence the behavior of other cell types through direct cell-cell interactions or paracrine signaling.\nClinically and in research, stromal cells often draw attention due to their interaction with tumors in the cancer microenvironment. Over the past years, the role of stromal cells as facilitators of tumor growth and metastasis has been recognized increasingly. They contribute to cancer progression not only by modulating the ECM but also through the secretion of various bioactive molecules and interacting with immune cells, thereby influencing the immunologic responses to tumors.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stromal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stromal cell" @@ -1312,7 +1632,13 @@ }, { "val" : "CALOHA:TS-0683" }, { - "val" : "FBbt:00005106" + "val" : "FBbt:00005106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54527" }, { @@ -1320,7 +1646,13 @@ }, { "val" : "WBbt:0003679" }, { - "val" : "ZFA:0009248" + "val" : "ZFA:0009248", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1349,7 +1681,13 @@ }, { "val" : "FMA:83377" }, { - "val" : "ZFA:0009249" + "val" : "ZFA:0009249", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -1408,7 +1746,13 @@ "xrefs" : [ { "val" : "FMA:83505" }, { - "val" : "ZFA:0005236" + "val" : "ZFA:0005236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1453,7 +1797,13 @@ "xrefs" : [ { "val" : "FMA:83506" }, { - "val" : "ZFA:0005241" + "val" : "ZFA:0005241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1594,7 +1944,13 @@ "val" : "A megakaryocyte is a large, unique, and complex cell type found primarily in the bone marrow, the spongy, semi-solid tissue located in the medullary cavities of certain bones. The term ‘megakaryocyte’ is derived from the Greek 'mega', meaning great, and 'karyon', referring to the nucleus. Megakaryocytes are characterized by their large size, typically with a diameter of 50-100 µm in humans, and the presence of a multilobulated nucleus; they are the largest hematopoietic cells in the bone marrow but also the rarest cells. \nThe primary function of a megakaryocyte is the production of platelets, also known as thrombocytes. Platelets are small, anucleate cell fragments that play a crucial role in the process of hemostasis, the arrest of blood loss from a damaged blood vessel. The process begins when the megakaryocyte extends long, branching processes called proplatelets, into the sinusoidal blood vessels present in the bone marrow. These proplatelets then fragment into the discoid structures recognized as platelets. Each megakaryocyte can produce thousands of platelets during its lifespan. \nApart from platelet production, megakaryocytes are involved in several other functions. They express immune-sensing receptors such as Fc-γ receptor and Toll-like receptors and produce factors such as platelet factor 4 and platelet-derived growth factor that can stimulate the immune system. Also, in certain pathological conditions, megakaryocytes release TGF-β and PDGF and contribute to bone marrow fibrosis, a condition characterized by excessive accumulation of fibrous tissue in the bone marrow leading to anemia. Recent studies have also highlighted the role of megakaryocytes in regulating hematopoiesis, the process of blood cell production. They can influence the bone marrow microenvironment and control the behavior of hematopoietic stem cells, the progenitors of all types of blood cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1614,7 +1970,13 @@ }, { "val" : "MESH:D012156" }, { - "val" : "ZFA:0009252" + "val" : "ZFA:0009252", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1640,7 +2002,13 @@ "val" : "chondroplast" } ], "xrefs" : [ { - "val" : "ZFA:0009258" + "val" : "ZFA:0009258", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1658,14 +2026,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009291" + "val" : "ZFA:0009291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Muscle precursor cells, commonly referred to as myogenic progenitor cells or myoblasts, play a pivotal role in the intricate processes of muscle regeneration and development. As undifferentiated cells, they harbor the potential to evolve into distinct specialized cells, specifically the muscle cell or myocyte. Their crucial contribution lies in guiding the transformation of the mesodermal layer, one of the three primary germ cell layers in the early embryo, into fully developed skeletal muscle tissues during embryonic development.\nMuscle precursor cells are characterized by their proliferative capacity and rapid differentiation into mature myocytes. They fuse into myotubes, culminating in the formation of muscle fibers. Their responsiveness to signals such as insulin-like growth factors, transforming growth factor-β, and neural inputs enables precise control over their proliferation and differentiation. This regenerative capacity equips them with the ability to repair injured or damaged muscle tissue, a critical function in preserving muscle homeostasis and overall function. These cells also actively contribute to adaptive responses, such as muscle growth and strengthening, in reaction to factors like training or aging.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "muscle precursor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle precursor cell" @@ -1686,14 +2066,26 @@ }, { "val" : "MESH:D053687" }, { - "val" : "ZFA:0009307" + "val" : "ZFA:0009307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Somatic stem cells, also known as adult stem cells, are undifferentiated cells found throughout the body post-embryonic development. They reside in specialized niches within tissues such as the bone marrow, brain, muscles, skin, and liver. Fundamentally, these cells possess the ability to self-renew, maintaining their numbers, and to generate differentiated cells that replace dying cells and repair damaged tissues. \nThe potency of somatic stem cells varies based on their tissue of origin. For instance, hematopoietic stem cells in the bone marrow exhibit multipotency, giving rise to all blood cell types. Conversely, muscle stem cells display unipotency, generating only muscle cells.\nSomatic stem cells respond to environmental signals that regulate their quiescence, activation, and differentiation states. In response to tissue injury, they proliferate and differentiate into specific mature cell types to replace lost or damaged cells. Intricate mechanisms ensure a delicate balance between self-renewal and differentiation, guiding tissue maintenance and repair without risking aberrant cell proliferation leading to tumor formation.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "somatic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somatic stem cell" @@ -1716,7 +2108,13 @@ }, { "val" : "MESH:D022423" }, { - "val" : "ZFA:0009324" + "val" : "ZFA:0009324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1745,7 +2143,13 @@ }, { "val" : "FMA:83516" }, { - "val" : "ZFA:0009325" + "val" : "ZFA:0009325", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1778,7 +2182,13 @@ }, { "val" : "MESH:D004900" }, { - "val" : "ZFA:0005237" + "val" : "ZFA:0005237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1808,7 +2218,13 @@ }, { "val" : "CALOHA:TS-0448" }, { - "val" : "ZFA:0009354" + "val" : "ZFA:0009354", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1840,7 +2256,13 @@ }, { "val" : "FMA:70339" }, { - "val" : "ZFA:0009356" + "val" : "ZFA:0009356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1879,7 +2301,13 @@ }, { "val" : "FMA:83598" }, { - "val" : "ZFA:0005830" + "val" : "ZFA:0005830", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1910,7 +2338,13 @@ "val" : "2011-11-16T04:28:16Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0001035" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0001035", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "bone cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1969,7 +2403,13 @@ "xrefs" : [ { "val" : "FMA:69074" }, { - "val" : "ZFA:0009385" + "val" : "ZFA:0009385", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -1999,7 +2439,13 @@ "xrefs" : [ { "val" : "FMA:69076" }, { - "val" : "ZFA:0009388" + "val" : "ZFA:0009388", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2045,7 +2491,13 @@ "val" : "2010-08-24T02:06:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "endothelial cell of vascular tree on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "endothelial cell of vascular tree" @@ -2118,7 +2570,13 @@ }, { "val" : "MESH:D003239" }, { - "val" : "ZFA:0009392" + "val" : "ZFA:0009392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2148,7 +2606,13 @@ }, { "val" : "WBbt:0007028" }, { - "val" : "ZFA:0007089" + "val" : "ZFA:0007089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2161,7 +2625,13 @@ "val" : "2010-09-15T03:39:21Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "embryonic cell (metazoa) on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "embryonic cell (metazoa)" @@ -2240,7 +2710,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007084" + "val" : "ZFA:0007084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2289,7 +2765,13 @@ "val" : "Mesenchymal cells are a type of undifferentiated cell that possess the ability to develop into a wide variety of other cells. These cells originate from the mesoderm during embryonic development, which gives rise to tissues such as muscles, the skeletal system, and connective and vascular structures. Mesenchymal cells primarily function as progenitor cells with exceptional renewal capabilities and are characterized by their ability to migrate, aiding in tissue repair and regeneration.\nMesenchymal cells play a critical role in the development and maintenance of various biological systems throughout the body due to their versatility and adaptability. They can differentiate into more specialized cells, including osteoblasts, adipocytes, and chondrocytes, which are essential for bone, fat, and cartilage tissues, respectively. Furthermore, they contribute to the vascular and lymphatic systems through the formation of pericytes and lymphatic endothelial cells, securing the integrity of the circulatory system.\nIn the field of regenerative medicine, mesenchymal cells, particularly mesenchymal stem cells (MSCs), are of great interest due to their unique therapeutic potential. MSCs, for instance, have been implicated in wound healing and tissue repair because of their capacity to modulate the immune response. They can secrete a range of proteins and growth factors that aid in angiogenesis, the formation of new blood vessels, and the stimulation of resident progenitor cells to aid in tissue restoration.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesenchymal cell" @@ -2330,7 +2812,13 @@ "val" : "Neural crest cells are a group of transient and highly migratory cells that originate from the neuroectoderm during the early stages of embryonic development. They are multipotent cells with an exceptional degree of plasticity, capable of differentiating into various somatic cell types and therefore play a fundamental role in the formation of various organs and tissues, making them critical contributors to the developing embryo. \nAfter the initiation of neurulation (the formation of the neural tube) neural crest cells start to undergo epithelial-to-mesenchymal transition and delaminate and migrate from the dorsal neural tube to several regions throughout the embryo. They differentiate into a range of diverse cell types, such as neurons and glial cells of the peripheral nervous system, including sensory and autonomic neurons. They also contribute to the formation of adrenal glands, pigment cells in the skin (melanocytes), cardiac structures, including parts of the heart septum and major arteries, as well as bones and cartilage of the face and skull.\nDisorders or aberrations in the development or migration of the neural crest cells can lead to serious congenital malformations, such as neurocristopathies, including Hirschsprung disease, neuroblastoma, and neurofibromatosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "neural crest cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "neural crest cell" @@ -2448,7 +2936,13 @@ }, { "val" : "MetaCyc:PEPTIDYLTRANSFERASE-RXN" }, { - "val" : "Reactome:R-HSA-156912" + "val" : "Reactome:R-HSA-156912", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Peptide transfer from P-site tRNA to the A-site tRNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -2456,6 +2950,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25493" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -2504,7 +3001,13 @@ "val" : "mitosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-69278" + "val" : "Reactome:R-HSA-69278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle, Mitotic" + } ] + } }, { "val" : "Wikipedia:Mitosis" } ], @@ -2694,7 +3197,13 @@ "xrefs" : [ "GOC:dph", "GOC:sdb_2009", "GOC:tb" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9823730" + "val" : "Reactome:R-HSA-9823730", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Formation of definitive endoderm" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3005,6 +3514,9 @@ "val" : "molecular function" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is the same as GO molecular function" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -3632,7 +4144,13 @@ "val" : "protein translation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72766" + "val" : "Reactome:R-HSA-72766", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Translation" + } ] + } }, { "val" : "Wikipedia:Translation_(genetics)" } ], @@ -3665,7 +4183,13 @@ "val" : "translation initiation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72613" + "val" : "Reactome:R-HSA-72613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Initiation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3690,7 +4214,13 @@ "val" : "translation elongation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-156842" + "val" : "Reactome:R-HSA-156842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Elongation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3717,7 +4247,13 @@ "val" : "translational complex disassembly" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72764" + "val" : "Reactome:R-HSA-72764", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Termination" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3771,7 +4307,13 @@ "val" : "single-organism transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382551" + "val" : "Reactome:R-HSA-382551", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of small molecules" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -3799,7 +4341,13 @@ "val" : "ion transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-425393" + "val" : "Reactome:R-HSA-425393", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of inorganic cations/anions and amino acids/oligopeptides" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3867,7 +4415,13 @@ "val" : "signaling (initiator) caspase activity" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-109581" + "val" : "Reactome:R-HSA-109581", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptosis" + } ] + } }, { "val" : "Wikipedia:Apoptosis" } ], @@ -3917,7 +4471,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-445355" + "val" : "Reactome:R-HSA-445355", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Smooth Muscle Contraction" + } ] + } }, { "val" : "Wikipedia:Muscle_contraction" } ], @@ -3965,7 +4525,13 @@ "val" : "single-organism organelle organization" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1852241" + "val" : "Reactome:R-HSA-1852241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Organelle biogenesis and maintenance" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -3993,7 +4559,13 @@ "val" : "cell-division cycle" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1640170" + "val" : "Reactome:R-HSA-1640170", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle" + } ] + } }, { "val" : "Wikipedia:Cell_cycle" } ], @@ -4067,7 +4639,13 @@ "val" : "signalling pathway" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-212718" + "val" : "Reactome:R-HSA-212718", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "EGFR interacts with phospholipase C-gamma" + } ] + } }, { "val" : "Wikipedia:Signal_transduction" } ], @@ -4117,23 +4695,77 @@ "xrefs" : [ "GOC:dph" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-112316" - }, { - "val" : "Reactome:R-HSA-442720" - }, { - "val" : "Reactome:R-HSA-442729" - }, { - "val" : "Reactome:R-HSA-442742" - }, { - "val" : "Reactome:R-HSA-451307" - }, { - "val" : "Reactome:R-HSA-451308" - }, { - "val" : "Reactome:R-HSA-9619229" - }, { - "val" : "Reactome:R-HSA-9619483" - }, { - "val" : "Reactome:R-HSA-9620244" + "val" : "Reactome:R-HSA-112316", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Neuronal System" + } ] + } + }, { + "val" : "Reactome:R-HSA-442720", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through the activation of Adenylate Cyclase" + } ] + } + }, { + "val" : "Reactome:R-HSA-442729", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde" + } ] + } + }, { + "val" : "Reactome:R-HSA-442742", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" + } ] + } + }, { + "val" : "Reactome:R-HSA-451307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of Na-permeable kainate receptors" + } ] + } + }, { + "val" : "Reactome:R-HSA-451308", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of Ca-permeable Kainate Receptor" + } ] + } + }, { + "val" : "Reactome:R-HSA-9619229", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of RAC1 downstream of NMDARs" + } ] + } + }, { + "val" : "Reactome:R-HSA-9619483", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of AMPK downstream of NMDARs" + } ] + } + }, { + "val" : "Reactome:R-HSA-9620244", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Long-term potentiation" + } ] + } }, { "val" : "Wikipedia:Neurotransmission" } ], @@ -4184,7 +4816,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9758941" + "val" : "Reactome:R-HSA-9758941", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Gastrulation" + } ] + } }, { "val" : "Wikipedia:Gastrulation" } ], @@ -4222,7 +4860,13 @@ "val" : "pan-neural process" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9675108" + "val" : "Reactome:R-HSA-9675108", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Nervous system development" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -4286,7 +4930,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8935690" + "val" : "Reactome:R-HSA-8935690", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Digestion" + } ] + } }, { "val" : "Wikipedia:Digestion" } ], @@ -4392,7 +5042,13 @@ "val" : "metabolism" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1430728" + "val" : "Reactome:R-HSA-1430728", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism" + } ] + } }, { "val" : "Wikipedia:Metabolism" } ], @@ -4754,7 +5410,13 @@ "val" : "embryonal development" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-5619507" + "val" : "Reactome:R-HSA-5619507", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of HOX genes during differentiation" + } ] + } }, { "val" : "Wikipedia:Embryogenesis" } ], @@ -4949,7 +5611,13 @@ "val" : "caspase-independent apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-5357801" + "val" : "Reactome:R-HSA-5357801", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Programmed Cell Death" + } ] + } }, { "val" : "Wikipedia:Programmed_cell_death" } ], @@ -4986,7 +5654,13 @@ "xrefs" : [ "GOC:ai" ] }, "xrefs" : [ { - 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"val" : "Reactome:R-HSA-392499" + "val" : "Reactome:R-HSA-392499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of proteins" + } ] + } }, { "val" : "Wikipedia:Protein_metabolism" } ], @@ -5560,7 +6301,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -5574,6 +6315,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/26279" }, { @@ -5590,6 +6334,7 @@ "val" : "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:18391171" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "formation of a cell surface projection" @@ -5599,6 +6344,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -6176,6 +6924,9 @@ "val" : "protein-protein complex" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is not covalently bonded, which conflicts with changes to the parent definition." + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -6240,7 +6991,13 @@ "val" : "ATP hydrolysis coupled ion transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-983712" + "val" : "Reactome:R-HSA-983712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ion channel transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -6369,6 +7126,9 @@ "val" : "Wikipedia:Melanosome" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002161", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6237" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -6379,8 +7139,8 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "Any biological process involved in the maintenance of an internal steady state.", - "xrefs" : [ "GOC:jl", "ISBN:0395825172" ] + "val" : "Any biological process involved in the maintenance of an internal steady state. 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Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953897" + "val" : "Reactome:R-HSA-8953897", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cellular responses to stimuli" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -7665,11 +8437,29 @@ "val" : "ATP hydrolysis coupled transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382556" + "val" : "Reactome:R-HSA-382556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ABC-family proteins mediated transport" + } ] + } }, { - "val" : "Reactome:R-HSA-425407" + "val" : "Reactome:R-HSA-425407", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "SLC-mediated transmembrane transport" + } ] + } }, { - "val" : "Reactome:R-HSA-5223345" + "val" : "Reactome:R-HSA-5223345", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Miscellaneous transport and binding events" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", @@ -8099,11 +8889,29 @@ "val" : "induction of apoptosis by extracellular signals" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-193681" + "val" : "Reactome:R-HSA-193681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ceramide signalling" + } ] + } }, { - "val" : "Reactome:R-HSA-204998" + "val" : "Reactome:R-HSA-204998", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell death signalling via NRAGE, NRIF and NADE" + } ] + } }, { - "val" : "Reactome:R-HSA-75157" + "val" : "Reactome:R-HSA-75157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "FasL/ CD95L signaling" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -8133,7 +8941,13 @@ "val" : "apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-75153" + "val" : "Reactome:R-HSA-75153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptotic execution phase" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -8238,7 +9052,7 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098643", - "lbl" : "fibrillar collagen", + "lbl" : "fibrillar collagen complex", "type" : "CLASS", "meta" : { "definition" : { @@ -8248,6 +9062,9 @@ "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "banded collagen fibril" + }, { + "pred" : "hasExactSynonym", + "val" : "fibrillar collagen" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -8291,14 +9108,21 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098645", - "lbl" : "collagen network", + "lbl" : "complex of network-forming collagens", "type" : "CLASS", "meta" : { "definition" : { "val" : "A supramolecular complex that consists of collagen triple helices associated to form a network.", "xrefs" : [ "GOC:dos", "PMID:21421911" ] }, + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "collagen network" + } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30938" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -8405,8 +9229,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.", - "xrefs" : [ "GOC:kmv" ] + "val" : "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { @@ -8414,6 +9237,12 @@ "val" : "cellular anatomical entity" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Overlaps with some cellular components from GO" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" }, { @@ -9004,6 +9833,37 @@ "val" : "Euteleostomi" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_119089", + "lbl" : "Chromadorea", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Adenophorea" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794", + "lbl" : "Ecdysozoa", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_131567", "lbl" : "cellular organisms", @@ -9223,6 +10083,32 @@ "val" : "ncbi_taxonomy" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116", + "lbl" : "Rhabditina", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119", + "lbl" : "Rhabditomorpha", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "lbl" : "Eukaryota", @@ -9268,6 +10154,46 @@ "val" : "Eukaryota" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "lbl" : "Choanoflagellata", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "choanoflagellates" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellatea" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellida" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanomonada" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanozoa" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "choanoflagellates" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + }, { + "val" : "PMID:27765632" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "lbl" : "Euarchontoglires", @@ -9460,6 +10386,19 @@ "val" : "Bilateria" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_33317", + "lbl" : "Protostomia", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_33511", "lbl" : "Deuterostomia", @@ -9719,6 +10658,32 @@ "val" : "ncbi_taxonomy" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_55879", + "lbl" : "Rhabditoidea", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_55885", + "lbl" : "Peloderinae", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6072", "lbl" : "Eumetazoa", @@ -9735,6 +10700,88 @@ "val" : "Eumetazoa" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6231", + "lbl" : "Nematoda", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "nematode" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "nematodes" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "roundworm" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003003", + "pred" : "hasExactSynonym", + "val" : "roundworms" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Nemata" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "nematodes" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6236", + "lbl" : "Rhabditida", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Strongylida" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6237", + "lbl" : "Caenorhabditis", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_6243", + "lbl" : "Rhabditidae", + "type" : "CLASS", + "meta" : { + "xrefs" : [ { + "val" : "GC_ID:1" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_7711", "lbl" : "Chordata", @@ -10305,6 +11352,21 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0001591", + "lbl" : "curvature", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.", + "xrefs" : [ "WordNet:WordNet" ] + }, + "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0001690", "lbl" : "contractile", @@ -10600,6 +11662,32 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0002254", + "lbl" : "flattened", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane.", + "xrefs" : [ "PATOC:CVS" ] + }, + "comments" : [ "Becoming flat but not necessarily completely flat." ], + "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], + "synonyms" : [ { + "pred" : "hasRelatedSynonym", + "val" : "compressed" + } ], + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0002-2061-091X" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2010-08-16T03:59:34Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002266", "lbl" : "3-D shape", @@ -11951,7 +13039,13 @@ }, { "val" : "TAO:0005425" }, { - "val" : "UMLS:C0036760" + "val" : "UMLS:C0036760", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Serosa" + } ] + } }, { "val" : "Wikipedia:Serous_membrane" }, { @@ -12017,7 +13111,13 @@ "xrefs" : [ { "val" : "AAO:0011123" }, { - "val" : "FBbt:00100314" + "val" : "FBbt:00100314", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:30320" }, { @@ -12027,7 +13127,13 @@ }, { "val" : "TAO:0005171" }, { - "val" : "UMLS:C0687028" + "val" : "UMLS:C0687028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Duct" + } ] + } }, { "val" : "Wikipedia:Duct_(anatomy)" }, { @@ -12107,7 +13213,13 @@ }, { "val" : "FAO:0000001" }, { - "val" : "FBbt:00007001" + "val" : "FBbt:00007001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:305751" }, { @@ -12192,7 +13304,13 @@ }, { "val" : "SCTID:272625005" }, { - "val" : "UMLS:C0178784" + "val" : "UMLS:C0178784", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ" + } ] + } }, { "val" : "WBbt:0003760" }, { @@ -12200,7 +13318,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33090" @@ -12320,47 +13444,161 @@ }, { "val" : "BilaDO:0000004" }, { - "val" : "BtauDv:0000078" - }, { - "val" : "CfamDv:0000007" - }, { - "val" : "ChirDv:0000014" - }, { - "val" : "DpseDv:0000005" - }, { - "val" : "DsimDv:0000005" + "val" : "BtauDv:0000078", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001272" }, { - "val" : "EcabDv:0000007" + "val" : "EcabDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005369" }, { - "val" : "FcatDv:0000007" - }, { - "val" : "GgalDv:0000076" - }, { - "val" : "GgorDv:0000032" - }, { - "val" : "HsapDv:0010000" - }, { - "val" : "MmulDv:0000052" - }, { - "val" : "MmusDv:0000092" - }, { - "val" : "OanaDv:0000007" - }, { - "val" : "OariDv:0000024" - }, { - "val" : "PpanDv:0000041" - }, { - "val" : "PtroDv:0000052" - }, { - "val" : "RnorDv:0000061" - }, { - "val" : "SsalDv:0000040" - }, { - "val" : "SscrDv:0000084" + "val" : "FcatDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000076", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000032", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0010000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000041", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000061", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000041" }, { @@ -12391,65 +13629,203 @@ "val" : "embryogenesis" } ], "xrefs" : [ { - "val" : "AcarDv:0000002" + "val" : "AcarDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BilaDO:0000002" }, { - "val" : "BtauDv:0000002" - }, { - "val" : "CfamDv:0000002" - }, { - "val" : "ChirDv:0000002" - }, { - "val" : "CporDv:0000002" - }, { - "val" : "DpseDv:0000002" - }, { - "val" : "DsimDv:0000002" + "val" : "BtauDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EV:0300001" }, { - "val" : "EcabDv:0000002" + "val" : "EcabDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005289" }, { "val" : "FMA:72652" }, { - "val" : "FcatDv:0000002" - }, { - "val" : "GgalDv:0000002" - }, { - "val" : "GgorDv:0000002" - }, { - "val" : "HsapDv:0000045" - }, { - "val" : "MdomDv:0000002" - }, { - "val" : "MmulDv:0000002" - }, { - "val" : "MmusDv:0000042" + "val" : "FcatDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : 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"val" : "SscrDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000003" }, { @@ -12522,7 +13898,13 @@ }, { "val" : "SCTID:118966000" }, { - "val" : "UMLS:C1519343" + "val" : "UMLS:C1519343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System_Part" + } ] + } }, { "val" : "galen:ComplexSkeletalStructure" } ], @@ -12559,7 +13941,13 @@ }, { "val" : "OGES:000024" }, { - "val" : "SsalDv:0000038" + "val" : "SsalDv:0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000022" }, { @@ -12629,55 +14017,193 @@ "val" : "lifespan" } ], "xrefs" : [ { - "val" : "AcarDv:0000001" - }, { - "val" : "BtauDv:0000001" - }, { - "val" : "CfamDv:0000001" - }, { - "val" : "ChirDv:0000001" - }, { - "val" : "CporDv:0000001" - }, { - "val" : "DpseDv:0000001" - }, { - "val" : "DsimDv:0000001" - }, { - "val" : "EcabDv:0000001" + "val" : "AcarDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "BtauDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "EcabDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00000000" }, { - "val" : "FcatDv:0000001" - }, { - "val" : "GgalDv:0000001" - }, { 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"val" : "MdomDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000011" }, { - "val" : "OanaDv:0000001" - }, { - "val" : "OariDv:0000001" - }, { - "val" : "OcunDv:0000001" - }, { - "val" : "PpanDv:0000001" - }, { - "val" : "PtroDv:0000001" - }, { - "val" : "RnorDv:0000001" - }, { - "val" : "SsalDv:0000001" - }, { - "val" : "SscrDv:0000001" + "val" : "OanaDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : 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: { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "ncithesaurus:Life" } ], @@ -12716,63 +14242,201 @@ "val" : "stage" } ], "xrefs" : [ { - "val" : "AcarDv:0000000" + "val" : "AcarDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BILS:0000105" }, { - "val" : "BtauDv:0000000" - }, { - "val" : 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"DpseDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0000399" }, { - "val" : "EcabDv:0000000" + "val" : "EcabDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00007012" }, { "val" : "FMA:24120" }, { - "val" : "FcatDv:0000000" - }, { - "val" : "GgalDv:0000000" - }, { - "val" : "GgorDv:0000000" - }, { - "val" : "HsapDv:0000000" + "val" : "FcatDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D008018" }, { - "val" : "MdomDv:0000000" - }, { - "val" : "MmulDv:0000000" - }, { - "val" : "MmusDv:0000000" - }, { - "val" : "OanaDv:0000000" - }, { - "val" : "OariDv:0000000" - }, { - "val" : "OcunDv:0000000" + "val" : "MdomDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000090" }, { - "val" : "PpanDv:0000000" - }, { - "val" : "PtroDv:0000000" - }, { - "val" : "RnorDv:0000000" - }, { - "val" : "SsalDv:0000000" - }, { - "val" : "SscrDv:0000000" + "val" : "PpanDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000002" }, { @@ -12843,7 +14507,13 @@ }, { "val" : "BilaDO:0000005" }, { - "val" : "ChirDv:0000003" + "val" : "ChirDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001322" }, { @@ -12851,21 +14521,57 @@ }, { "val" : "FBdv:00005288" }, { - "val" : "HsapDv:0000003" - }, { - "val" : "MmusDv:0000003" + "val" : "HsapDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "NCIT:C12601" }, { - "val" : "OariDv:0000009" + "val" : "OariDv:0000009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000100" }, { - "val" : "RnorDv:0000048" - }, { - "val" : "SsalDv:0000003" - }, { - "val" : "SscrDv:0000087" + "val" : "RnorDv:0000048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "VHOG:0000745" }, { @@ -12898,33 +14604,81 @@ }, { "val" : "BilaDO:0000006" }, { - "val" : "ChirDv:0000004" + "val" : "ChirDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001290" }, { "val" : "FBdv:00000054" }, { - "val" : "GgalDv:0000064" - }, { - "val" : "HsapDv:0000005" + "val" : "GgalDv:0000064", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D002970" }, { - "val" : "MmusDv:0000004" + "val" : "MmusDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000015" }, { "val" : "OGES:000020" }, { - "val" : "OariDv:0000010" + "val" : "OariDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000200" }, { - "val" : "RnorDv:0000049" - }, { - "val" : "SsalDv:0000004" - }, { - "val" : "SscrDv:0000088" + "val" : "RnorDv:0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000088", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Cleavage_(embryo)" }, { @@ -12952,15 +14706,39 @@ }, { "val" : "BilaDO:0000007" }, { - "val" : "ChirDv:0000010" + "val" : "ChirDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001282" }, { - "val" : "GgalDv:0000091" - }, { - "val" : "HsapDv:0000006" - }, { - "val" : "MmusDv:0000007" + "val" : "GgalDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000003" }, { @@ -12968,13 +14746,37 @@ }, { "val" : "OGES:000021" }, { - "val" : "OariDv:0000025" - }, { - "val" : "RnorDv:0000054" - }, { - "val" : "SsalDv:0000012" - }, { - "val" : "SscrDv:0000089" + "val" : "OariDv:0000025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000005" }, { @@ -13035,29 +14837,77 @@ }, { "val" : "BilaDO:0000008" }, { - "val" : "ChirDv:0000011" + "val" : "ChirDv:0000011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001296" }, { "val" : "FBdv:00005317" }, { - "val" : "GgalDv:0000092" - }, { - "val" : "HsapDv:0000010" - }, { - "val" : "MmusDv:0000013" + "val" : "GgalDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000004" }, { "val" : "OGES:000019" }, { - "val" : "OariDv:0000026" - }, { - "val" : "RnorDv:0000005" - }, { - "val" : "SsalDv:0000016" - }, { - "val" : "SscrDv:0000090" + "val" : "OariDv:0000026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000010" }, { @@ -13084,19 +14934,61 @@ }, { "val" : "BilaDO:0000009" }, { - "val" : "ChirDv:0000012" - }, { - "val" : "GgalDv:0000093" - }, { - "val" : "HsapDv:0000012" - }, { - "val" : "MmusDv:0000017" - }, { - "val" : "OariDv:0000027" - }, { - "val" : "RnorDv:0000007" - }, { - "val" : "SscrDv:0000091" + "val" : "ChirDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "XAO:1000006" } ], @@ -13129,25 +15021,73 @@ }, { "val" : "BilaDO:0000010" }, { - "val" : "ChirDv:0000013" - }, { - "val" : "GgalDv:0000094" - }, { - "val" : "HsapDv:0000015" - }, { - "val" : "MmusDv:0000018" + "val" : "ChirDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000018", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000005" }, { "val" : "OGES:000032" }, { - "val" : "OariDv:0000028" - }, { - "val" : "RnorDv:0000055" - }, { - "val" : "SsalDv:0000022" - }, { - "val" : "SscrDv:0000086" + "val" : "OariDv:0000028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Organogenesis" } ], @@ -13246,7 +15186,13 @@ }, { "val" : "EMAPA:16262" }, { - "val" : "FBbt:00003126" + "val" : "FBbt:00003126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:49184" }, { @@ -13362,7 +15308,13 @@ }, { "val" : "TAO:0000007" }, { - "val" : "UMLS:C0005767" + "val" : "UMLS:C0005767", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood" + } ] + } }, { "val" : "VHOG:0000224" }, { @@ -13552,7 +15504,13 @@ "xrefs" : [ { "val" : "BTO:0001837" }, { - "val" : "EMAPA:37950" + "val" : "EMAPA:37950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:62889" }, { @@ -13621,7 +15579,13 @@ }, { "val" : "NCIT:C34062" }, { - "val" : "UMLS:C1516992" + "val" : "UMLS:C1516992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland_Fluid_or_Secretion" + } ] + } }, { "val" : "galen:Secretion" } ], @@ -13676,7 +15640,13 @@ }, { "val" : "EMAPA:35178" }, { - "val" : "FBbt:00007019" + "val" : "FBbt:00007019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9669" }, { @@ -13750,7 +15720,13 @@ }, { "val" : "EHDAA2:0003005" }, { - "val" : "FBbt:00007017" + "val" : "FBbt:00007017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:5897" }, { @@ -13762,7 +15738,13 @@ }, { "val" : "TGMA:0001825" }, { - "val" : "UMLS:C0524461" + "val" : "UMLS:C0524461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lumen_Space" + } ] + } }, { "val" : "VHOG:0001728" }, { @@ -13805,7 +15787,13 @@ }, { "val" : "EHDAA2:0003006" }, { - "val" : "FBbt:00007016" + "val" : "FBbt:00007016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67165" }, { @@ -13857,7 +15845,13 @@ }, { "val" : "EHDAA2:0003007" }, { - "val" : "FBbt:00007015" + "val" : "FBbt:00007015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67112" }, { @@ -13937,7 +15931,13 @@ }, { "val" : "EV:0100000" }, { - "val" : "FBbt:00004856" + "val" : "FBbt:00004856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7149" }, { @@ -13953,7 +15953,13 @@ }, { "val" : "TGMA:0001831" }, { - "val" : "UMLS:C0460002" + "val" : "UMLS:C0460002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_System" + } ] + } }, { "val" : "VHOG:0001725" }, { @@ -14051,7 +16057,13 @@ }, { "val" : "EV:0100016" }, { - "val" : "FBbt:00000001" + "val" : "FBbt:00000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:256135" }, { @@ -14143,7 +16155,13 @@ }, { "val" : "EMAPA:36031" }, { - "val" : "FBbt:00007009" + "val" : "FBbt:00007009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7153" }, { @@ -14163,7 +16181,13 @@ }, { "val" : "TGMA:0001840" }, { - "val" : "UMLS:C0229962" + "val" : "UMLS:C0229962", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Body_Part" + } ] + } }, { "val" : "VHOG:0001758" }, { @@ -14219,7 +16243,13 @@ }, { "val" : "EHDAA2:0003040" }, { - "val" : "FBbt:00007013" + "val" : "FBbt:00007013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:63863" }, { @@ -14258,7 +16288,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007277" + "val" : "FBbt:00007277", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "VHOG:0001737" } ], @@ -14314,7 +16350,13 @@ }, { "val" : "EHDAA:46" }, { - "val" : "FBbt:00005835" + "val" : "FBbt:00005835", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85537" }, { @@ -14328,7 +16370,13 @@ }, { "val" : "TGMA:0001843" }, { - "val" : "UMLS:C1282438" + "val" : "UMLS:C1282438", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Extraembryonic_Structure" + } ] + } }, { "val" : "VHOG:0000292" }, { @@ -14382,7 +16430,13 @@ }, { "val" : "EMAPA:35868" }, { - "val" : "FBbt:00007003" + "val" : "FBbt:00007003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9637" }, { @@ -14398,7 +16452,13 @@ }, { "val" : "TGMA:0001844" }, { - "val" : "UMLS:C0040300" + "val" : "UMLS:C0040300", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Tissue" + } ] + } }, { "val" : "VHOG:0001757" }, { @@ -14454,7 +16514,13 @@ }, { "val" : "EHDAA2:0003055" }, { - "val" : "FBbt:00007010" + "val" : "FBbt:00007010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000055" }, { @@ -14520,7 +16586,13 @@ }, { "val" : "EMAPA:32738" }, { - "val" : "FBbt:00007005" + "val" : "FBbt:00007005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9639" }, { @@ -14538,7 +16610,13 @@ }, { "val" : "TAO:0001486" }, { - "val" : "UMLS:C0014609" + "val" : "UMLS:C0014609", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Epithelium" + } ] + } }, { "val" : "VHOG:0000387" }, { @@ -14597,7 +16675,13 @@ }, { "val" : "TAO:0001494" }, { - "val" : "UMLS:C0682575" + "val" : "UMLS:C0682575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stratified_Epithelium" + } ] + } }, { "val" : "Wikipedia:Stratified_epithelium" }, { @@ -14650,7 +16734,13 @@ }, { "val" : "TAO:0001498" }, { - "val" : "UMLS:C0836133" + "val" : "UMLS:C0836133", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_squamous_epithelium" }, { @@ -14709,7 +16799,13 @@ }, { "val" : "TAO:0001495" }, { - "val" : "UMLS:C0682574" + "val" : "UMLS:C0682574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Epithelium" + } ] + } }, { "val" : "XAO:0004007" }, { @@ -14809,7 +16905,13 @@ }, { "val" : "EMAPA:16039" }, { - "val" : "FBbt:00000052" + "val" : "FBbt:00000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69068" }, { @@ -14827,7 +16929,13 @@ }, { "val" : "SCTID:57991002" }, { - "val" : "UMLS:C0013935" + "val" : "UMLS:C0013935", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryo" + } ] + } }, { "val" : "VHOG:0001766" }, { @@ -14889,7 +16997,13 @@ }, { "val" : "EMAPA:36033" }, { - "val" : "FBbt:00000110" + "val" : "FBbt:00000110", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69069" }, { @@ -14903,9 +17017,21 @@ }, { "val" : "TAO:0001122" }, { - "val" : "UMLS:C0920502" - }, { - "val" : "UMLS:C1708239" + "val" : "UMLS:C0920502", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Tissue" + } ] + } + }, { + "val" : "UMLS:C1708239", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Germinal_Layer" + } ] + } }, { "val" : "VHOG:0001223" }, { @@ -14952,7 +17078,13 @@ }, { "val" : "EV:0100003" }, { - "val" : "FBbt:00000111" + "val" : "FBbt:00000111", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69070" }, { @@ -14972,7 +17104,13 @@ }, { "val" : "TAO:0000016" }, { - "val" : "UMLS:C0013574" + "val" : "UMLS:C0013574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ectoderm" + } ] + } }, { "val" : "VHOG:0000153" }, { @@ -15023,7 +17161,13 @@ }, { "val" : "EV:0100005" }, { - "val" : "FBbt:00000125" + "val" : "FBbt:00000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69071" }, { @@ -15041,7 +17185,13 @@ }, { "val" : "TAO:0000017" }, { - "val" : "UMLS:C0014144" + "val" : "UMLS:C0014144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endoderm" + } ] + } }, { "val" : "VHOG:0000154" }, { @@ -15107,7 +17257,13 @@ }, { "val" : "EV:0100006" }, { - "val" : "FBbt:00000126" + "val" : "FBbt:00000126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69072" }, { @@ -15125,7 +17281,13 @@ }, { "val" : "TAO:0000041" }, { - "val" : "UMLS:C0025485" + "val" : "UMLS:C0025485", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesoderm" + } ] + } }, { "val" : "VHOG:0000152" }, { @@ -15195,7 +17357,13 @@ }, { "val" : "EMAPA:16263" }, { - "val" : "FBbt:00000439" + "val" : "FBbt:00000439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:295846" }, { @@ -15205,7 +17373,13 @@ }, { "val" : "TGMA:0000135" }, { - "val" : "UMLS:C1514977" + "val" : "UMLS:C1514977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stomodeum" + } ] + } }, { "val" : "Wikipedia:Stomodeum" }, { @@ -15288,7 +17462,13 @@ }, { "val" : "TAO:0000114" }, { - "val" : "UMLS:C0018787" + "val" : "UMLS:C0018787", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Heart" + } ] + } }, { "val" : "VHOG:0000276" }, { @@ -15379,7 +17559,13 @@ }, { "val" : "TAO:0000367" }, { - "val" : "UMLS:C0022417" + "val" : "UMLS:C0022417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint" + } ] + } }, { "val" : "VHOG:0001276" }, { @@ -15432,7 +17618,13 @@ }, { "val" : "EFO:0000793" }, { - "val" : "FBbt:00005055" + "val" : "FBbt:00005055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7152" }, { @@ -15493,7 +17685,13 @@ }, { "val" : "CALOHA:TS-2103" }, { - "val" : "MESH:D002319" + "val" : "MESH:D002319", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "VHOG:0001248" }, { @@ -15501,7 +17699,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6073" @@ -15573,7 +17777,13 @@ }, { "val" : "TAO:0000548" }, { - "val" : "UMLS:C0026845" + "val" : "UMLS:C0026845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle" + } ] + } }, { "val" : "VSAO:0005038" }, { @@ -15636,7 +17846,13 @@ }, { "val" : "EV:0100162" }, { - "val" : "FBbt:00005093" + "val" : "FBbt:00005093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7157" }, { @@ -15656,7 +17872,13 @@ }, { "val" : "TAO:0000396" }, { - "val" : "UMLS:C0027763" + "val" : "UMLS:C0027763", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System" + } ] + } }, { "val" : "VHOG:0000402" }, { @@ -15740,7 +17962,13 @@ }, { "val" : "EV:0100163" }, { - "val" : "FBbt:00005094" + "val" : "FBbt:00005094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:55675" }, { @@ -15758,7 +17986,16 @@ }, { "val" : "TAO:0000012" }, { - "val" : "UMLS:C0927232" + "val" : "UMLS:C0927232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1099" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Central_Nervous_System" + } ] + } }, { "val" : "VHOG:0000293" }, { @@ -15772,7 +18009,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -15819,7 +18062,13 @@ }, { "val" : "EHDAA2:0003171" }, { - "val" : "FBbt:00005495" + "val" : "FBbt:00005495", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86589" }, { @@ -15827,7 +18076,13 @@ }, { "val" : "NCIT:C34275" }, { - "val" : "UMLS:C0678727" + "val" : "UMLS:C0678727", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium" + } ] + } }, { "val" : "Wikipedia:Primordium" }, { @@ -15891,7 +18146,13 @@ }, { "val" : "TAO:0001135" }, { - "val" : "UMLS:C0231024" + "val" : "UMLS:C0231024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Tube" + } ] + } }, { "val" : "VHOG:0000307" }, { @@ -15936,7 +18197,13 @@ }, { "val" : "EHDAA2:0002229" }, { - "val" : "FBbt:10000000" + "val" : "FBbt:10000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:62955" }, { @@ -15950,7 +18217,13 @@ }, { "val" : "TGMA:0001822" }, { - "val" : "UMLS:C1515976" + "val" : "UMLS:C1515976", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Structure_System_or_Substance" + } ] + } }, { "val" : "WBbt:0000100" }, { @@ -16006,7 +18279,13 @@ }, { "val" : "TAO:0005154" }, { - "val" : "UMLS:C0039097" + "val" : "UMLS:C0039097", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Synovial_Fluid" + } ] + } }, { "val" : "Wikipedia:Synovial_fluid" }, { @@ -16060,7 +18339,13 @@ }, { "val" : "SCTID:361918002" }, { - "val" : "UMLS:C0086610" + "val" : "UMLS:C0086610", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesothelium" + } ] + } }, { "val" : "Wikipedia:Mesothelium" } ], @@ -16115,7 +18400,13 @@ }, { "val" : "TAO:0000434" }, { - "val" : "UMLS:C0037253" + "val" : "UMLS:C0037253", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System" + } ] + } }, { "val" : "VHOG:0001254" }, { @@ -16197,7 +18488,13 @@ }, { "val" : "TAO:0001514" }, { - "val" : "UMLS:C0262950" + "val" : "UMLS:C0262950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bone" + } ] + } }, { "val" : "VHOG:0001190" }, { @@ -16247,7 +18544,13 @@ "xrefs" : [ "Wikipedia:Articular_capsule" ] } ], "xrefs" : [ { - "val" : "EMAPA:37621" + "val" : "EMAPA:37621", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:34836" }, { @@ -16263,7 +18566,13 @@ }, { "val" : "SCTID:182238002" }, { - "val" : "UMLS:C0206207" + "val" : "UMLS:C0206207", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint_Capsule" + } ] + } }, { "val" : "Wikipedia:Articular_capsule" }, { @@ -16329,13 +18638,25 @@ }, { "val" : "EMAPA:16247" }, { - "val" : "FBbt:00003125" + "val" : "FBbt:00003125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45615" }, { "val" : "MA:0000917" }, { - "val" : "MESH:D041981" + "val" : "MESH:D041981", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C34082" }, { @@ -16343,7 +18664,13 @@ }, { "val" : "TGMA:0001819" }, { - "val" : "UMLS:C0017189" + "val" : "UMLS:C0017189", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrointestinal_Tract" + } ] + } }, { "val" : "VHOG:0000309" }, { @@ -16355,10 +18682,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1371/journal.pone.0016309" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -16383,7 +18722,13 @@ "xrefs" : [ "ZFA:0005145" ] } ], "xrefs" : [ { - "val" : "EMAPA:37474" + "val" : "EMAPA:37474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100146" }, { @@ -16473,7 +18818,13 @@ }, { "val" : "TAO:0000005" }, { - "val" : "UMLS:C0003842" + "val" : "UMLS:C0003842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Artery" + } ] + } }, { "val" : "VHOG:0001251" }, { @@ -16562,7 +18913,13 @@ }, { "val" : "TAO:0000082" }, { - "val" : "UMLS:C0042449" + "val" : "UMLS:C0042449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vein" + } ] + } }, { "val" : "VHOG:0001743" }, { @@ -16633,7 +18990,13 @@ }, { "val" : "NCIT:C13356" }, { - "val" : "UMLS:C0032105" + "val" : "UMLS:C0032105", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Plasma" + } ] + } }, { "val" : "Wikipedia:Blood_plasma" } ], @@ -16675,7 +19038,13 @@ }, { "val" : "TAO:0005315" }, { - "val" : "UMLS:C0042520" + "val" : "UMLS:C0042520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venule" + } ] + } }, { "val" : "VHOG:0001765" }, { @@ -16729,7 +19098,13 @@ }, { "val" : "TAO:0002138" }, { - "val" : "UMLS:C0003847" + "val" : "UMLS:C0003847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Arteriole" + } ] + } }, { "val" : "VHOG:0001763" }, { @@ -16812,7 +19187,13 @@ }, { "val" : "TAO:0002137" }, { - "val" : "UMLS:C0005847" + "val" : "UMLS:C0005847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel" + } ] + } }, { "val" : "VHOG:0001250" }, { @@ -16878,7 +19259,13 @@ }, { "val" : "TAO:0005250" }, { - "val" : "UMLS:C0935624" + "val" : "UMLS:C0935624", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary" + } ] + } }, { "val" : "VHOG:0001253" }, { @@ -16933,7 +19320,13 @@ }, { "val" : "SCTID:27168002" }, { - "val" : "UMLS:C0014257" + "val" : "UMLS:C0014257", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endothelium" + } ] + } }, { "val" : "galen:Endothelium" } ], @@ -17025,7 +19418,13 @@ }, { "val" : "EFO:0000461" }, { - "val" : "FBbt:00004208" + "val" : "FBbt:00004208", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69067" }, { @@ -17041,7 +19440,13 @@ }, { "val" : "TAO:0001105" }, { - "val" : "UMLS:C0013948" + "val" : "UMLS:C0013948", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Structure" + } ] + } }, { "val" : "VSAO:0000178" }, { @@ -17105,7 +19510,13 @@ }, { "val" : "SCTID:118760003" }, { - "val" : "UMLS:C0042779" + "val" : "UMLS:C0042779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Viscera" + } ] + } }, { "val" : "Wikipedia:Viscus" }, { @@ -17144,7 +19555,13 @@ }, { "val" : "EHDAA:5049" }, { - "val" : "EMAPA:37721" + "val" : "EMAPA:37721", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71221" }, { @@ -17152,7 +19569,13 @@ }, { "val" : "MAT:0000148" }, { - "val" : "MESH:D013131" + "val" : "MESH:D013131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000148" }, { @@ -17226,7 +19649,13 @@ }, { "val" : "TAO:0001115" }, { - "val" : "UMLS:C0460005" + "val" : "UMLS:C0460005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trunk" + } ] + } }, { "val" : "Wikipedia:Torso" }, { @@ -17313,7 +19742,13 @@ }, { "val" : "SCTID:278858007" }, { - "val" : "UMLS:C0026860" + "val" : "UMLS:C0026860", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Musculoskeletal_System" + } ] + } }, { "val" : "VHOG:0001275" }, { @@ -17439,7 +19874,13 @@ }, { "val" : "SCTID:243949006" }, { - "val" : "UMLS:C0230139" + "val" : "UMLS:C0230139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Thoracic_Cavity" + } ] + } }, { "val" : "Wikipedia:Thoracic_cavity" } ], @@ -17511,7 +19952,13 @@ }, { "val" : "EHDAA2:0000267" }, { - "val" : "FBbt:00005060" + "val" : "FBbt:00005060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85006" }, { @@ -17523,7 +19970,13 @@ }, { "val" : "TAO:0001438" }, { - "val" : "UMLS:C0333343" + "val" : "UMLS:C0333343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cavity" + } ] + } }, { "val" : "galen:BodyCavity" } ], @@ -17587,7 +20040,13 @@ }, { "val" : "TAO:0000135" }, { - "val" : "UMLS:C0028439" + "val" : "UMLS:C0028439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochord" + } ] + } }, { "val" : "VHOG:0000199" }, { @@ -17683,7 +20142,13 @@ }, { "val" : "TAO:0000155" }, { - "val" : "UMLS:C0376449" + "val" : "UMLS:C0376449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somite" + } ] + } }, { "val" : "VHOG:0000191" }, { @@ -17695,7 +20160,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:17237766" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somite" @@ -17732,7 +20203,13 @@ }, { "val" : "NCIT:C12957" }, { - "val" : "UMLS:C1516995" + "val" : "UMLS:C1516995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_System" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" }, { @@ -17797,7 +20274,13 @@ }, { "val" : "SCTID:361462002" }, { - "val" : "UMLS:C0027789" + "val" : "UMLS:C0027789", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Crest" + } ] + } }, { "val" : "VHOG:0000057" }, { @@ -17869,7 +20352,13 @@ }, { "val" : "EV:0100004" }, { - "val" : "FBbt:00001057" + "val" : "FBbt:00001057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:87657" }, { @@ -17881,7 +20370,13 @@ }, { "val" : "TAO:0001120" }, { - "val" : "UMLS:C1518271" + "val" : "UMLS:C1518271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neuroectoderm" + } ] + } }, { "val" : "VHOG:0000150" }, { @@ -17939,7 +20434,13 @@ }, { "val" : "SCTID:115976003" }, { - "val" : "UMLS:C0015282" + "val" : "UMLS:C0015282", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" } ], @@ -18002,7 +20503,13 @@ }, { "val" : "TAO:0001641" }, { - "val" : "UMLS:C0009780" + "val" : "UMLS:C0009780", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Connective_Tissue" + } ] + } }, { "val" : "VSAO:0000017" }, { @@ -18070,7 +20577,13 @@ }, { "val" : "SCTID:91727004" }, { - "val" : "UMLS:C2328219" + "val" : "UMLS:C2328219", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle_Tissue" + } ] + } }, { "val" : "Wikipedia:Muscle_tissue" }, { @@ -18148,7 +20661,13 @@ }, { "val" : "TAO:0005023" }, { - "val" : "UMLS:C0018957" + "val" : "UMLS:C0018957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hematopoietic_System" + } ] + } }, { "val" : "VHOG:0001624" }, { @@ -18212,7 +20731,13 @@ }, { "val" : "NCIT:C13076" }, { - "val" : "UMLS:C0391978" + "val" : "UMLS:C0391978", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bone_Tissue" + } ] + } }, { "val" : "VSAO:0000047" }, { @@ -18271,7 +20796,13 @@ }, { "val" : "EMAPA:18425" }, { - "val" : "FBbt:00100317" + "val" : "FBbt:00100317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7146" }, { @@ -18289,7 +20820,13 @@ }, { "val" : "SCTID:134358001" }, { - "val" : "UMLS:C1285092" + "val" : "UMLS:C1285092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gland" + } ] + } }, { "val" : "Wikipedia:Gland" }, { @@ -18377,7 +20914,13 @@ "xrefs" : [ { "val" : "BIRNLEX:1011" }, { - "val" : "EMAPA:37442" + "val" : "EMAPA:37442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67552" }, { @@ -18495,7 +21038,13 @@ }, { "val" : "TE:E5.11.2.0.0.0.4" }, { - "val" : "UMLS:C1511224" + "val" : "UMLS:C1511224", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Island" + } ] + } }, { "val" : "VHOG:0000085" }, { @@ -18590,7 +21139,13 @@ }, { "val" : "TAO:0000132" }, { - "val" : "UMLS:C0920623" + "val" : "UMLS:C0920623", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Plate" + } ] + } }, { "val" : "VHOG:0000068" }, { @@ -18651,7 +21206,13 @@ }, { "val" : "TAO:0000255" }, { - "val" : "UMLS:C1284009" + "val" : "UMLS:C1284009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Paraxial_Mesoderm" + } ] + } }, { "val" : "VHOG:0000114" }, { @@ -18718,7 +21279,13 @@ }, { "val" : "TAO:0000121" }, { - "val" : "UMLS:C1517749" + "val" : "UMLS:C1517749", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lateral_Mesoderm" + } ] + } }, { "val" : "VHOG:0000118" }, { @@ -18763,7 +21330,13 @@ }, { "val" : "TAO:0000028" }, { - "val" : "UMLS:C1514450" + "val" : "UMLS:C1514450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium_of_the_Heart" + } ] + } }, { "val" : "XAO:0000336" }, { @@ -18813,7 +21386,13 @@ }, { "val" : "TAO:0001080" }, { - "val" : "UMLS:C0183176" + "val" : "UMLS:C0183176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclerotome" + } ] + } }, { "val" : "VHOG:0000680" }, { @@ -18920,7 +21499,13 @@ }, { "val" : "TAO:0000393" }, { - "val" : "UMLS:C0162415" + "val" : "UMLS:C0162415", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesenchyme" + } ] + } }, { "val" : "VHOG:0000170" }, { @@ -19006,7 +21591,13 @@ }, { "val" : "NCIT:C34195" }, { - "val" : "UMLS:C1512940" + "val" : "UMLS:C1512940", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intraembryonic_Coelom" + } ] + } }, { "val" : "VHOG:0000316" }, { @@ -19038,7 +21629,13 @@ }, { "val" : "EHDAA2:0003114" }, { - "val" : "FBbt:00007474" + "val" : "FBbt:00007474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -19467,7 +22064,13 @@ }, { "val" : "TAO:0000010" }, { - "val" : "UMLS:C0007226" + "val" : "UMLS:C0007226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiovascular_System" + } ] + } }, { "val" : "VHOG:0000302" }, { @@ -19593,7 +22196,13 @@ }, { "val" : "SCTID:362060003" }, { - "val" : "UMLS:C1267406" + "val" : "UMLS:C1267406", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venous_System" + } ] + } }, { "val" : "VHOG:0000277" } ], @@ -19625,7 +22234,13 @@ }, { "val" : "TAO:0005257" }, { - "val" : "UMLS:C1706972" + "val" : "UMLS:C1706972", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel_Endothelium" + } ] + } }, { "val" : "ZFA:0005257" } ], @@ -19663,7 +22278,13 @@ }, { "val" : "NCIT:C34131" }, { - "val" : "UMLS:C1516779" + "val" : "UMLS:C1516779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conceptus" + } ] + } }, { "val" : "Wikipedia:Conceptus" } ], @@ -19727,7 +22348,13 @@ }, { "val" : "BTO:0001403" }, { - "val" : "FBbt:00005317" + "val" : "FBbt:00005317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:293108" }, { @@ -19741,9 +22368,21 @@ }, { "val" : "NCIT:C34058" }, { - "val" : "UMLS:C0017199" - }, { - "val" : "UMLS:C1284022" + "val" : "UMLS:C0017199", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrula" + } ] + } + }, { + "val" : "UMLS:C1284022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trilaminar_Embryonic_Disc" + } ] + } }, { "val" : "Wikipedia:Gastrula" }, { @@ -19765,7 +22404,13 @@ }, "comments" : [ "Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from" ], "xrefs" : [ { - "val" : "EMAPA:37744" + "val" : "EMAPA:37744", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0003047" }, { @@ -19887,7 +22532,13 @@ }, { "val" : "TAO:0002171" }, { - "val" : "UMLS:C0014261" + "val" : "UMLS:C0014261", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_Endothelium" + } ] + } }, { "val" : "VHOG:0001217" }, { @@ -19996,7 +22647,13 @@ "val" : "joint" } ], "xrefs" : [ { - "val" : "FBbt:00005811" + "val" : "FBbt:00005811", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -20033,7 +22690,13 @@ "xrefs" : [ "FMA:71131" ] } ], "xrefs" : [ { - "val" : "FBbt:00100315" + "val" : "FBbt:00100315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:71131" } ], @@ -20086,7 +22749,13 @@ }, { "val" : "SCTID:361463007" }, { - "val" : "UMLS:C0814992" + "val" : "UMLS:C0814992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Groove" + } ] + } }, { "val" : "Wikipedia:Neural_groove" }, { @@ -20123,7 +22792,13 @@ }, { "val" : "SCTID:361461009" }, { - "val" : "UMLS:C0814993" + "val" : "UMLS:C0814993", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Fold" + } ] + } }, { "val" : "Wikipedia:Neural_fold" }, { @@ -20221,7 +22896,13 @@ "xrefs" : [ "MA:0000516" ] } ], "xrefs" : [ { - "val" : "EMAPA:37270" + "val" : "EMAPA:37270", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000516" } ], @@ -20246,7 +22927,13 @@ "xrefs" : [ "MA:0000557" ] } ], "xrefs" : [ { - "val" : "EMAPA:37273" + "val" : "EMAPA:37273", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000557" } ], @@ -20271,7 +22958,13 @@ "xrefs" : [ "MA:0000563" ] } ], "xrefs" : [ { - "val" : "EMAPA:37271" + "val" : "EMAPA:37271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000563" } ], @@ -20365,7 +23058,13 @@ }, { "val" : "EHDAA2:0003125" }, { - "val" : "FBbt:00007006" + "val" : "FBbt:00007006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:292313" }, { @@ -20489,13 +23188,25 @@ }, { "val" : "SCTID:68989006" }, { - "val" : "UMLS:C0004799" + "val" : "UMLS:C0004799", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Basement_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "http://palaeos.com/metazoa/porifera/homoscleromorpha.html" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "basement membrane of epithelium" @@ -20554,7 +23265,13 @@ }, { "val" : "SCTID:361725000" }, { - "val" : "UMLS:C0222645" + "val" : "UMLS:C0222645", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Axial_Skeleton" + } ] + } }, { "val" : "VSAO:0000056" }, { @@ -20598,7 +23315,13 @@ }, { "val" : "NCIT:C34231" }, { - "val" : "UMLS:C1518429" + "val" : "UMLS:C1518429", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Plate" + } ] + } }, { "val" : "VHOG:0001212" } ], @@ -20639,7 +23362,13 @@ }, { "val" : "NCIT:C34232" }, { - "val" : "UMLS:C1518430" + "val" : "UMLS:C1518430", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Process" + } ] + } }, { "val" : "VHOG:0001213" } ], @@ -20669,7 +23398,13 @@ "xrefs" : [ { "val" : "BIRNLEX:20" }, { - "val" : "EMAPA:37441" + "val" : "EMAPA:37441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:280556" }, { @@ -20837,7 +23572,13 @@ }, { "val" : "SCTID:40118003" }, { - "val" : "UMLS:C0221909" + "val" : "UMLS:C0221909", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Squamous_epithelium" } ], @@ -20890,7 +23631,13 @@ }, { "val" : "NCIT:C34022" }, { - "val" : "UMLS:C1515977" + "val" : "UMLS:C1515977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Surface" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -21009,7 +23756,13 @@ }, { "val" : "SCTID:360394002" }, { - "val" : "UMLS:C1514442" + "val" : "UMLS:C1514442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordial_Gut" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -21360,7 +24113,13 @@ }, { "val" : "EHDAA2:0003170" }, { - "val" : "FBbt:00005426" + "val" : "FBbt:00005426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "Wikipedia:Anlage_(biology)" } ], @@ -21447,7 +24206,13 @@ }, { "val" : "NCIT:C33854" }, { - "val" : "UMLS:C0489903" + "val" : "UMLS:C0489903", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_System" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -21604,7 +24369,13 @@ "xrefs" : [ { "val" : "CARO:0010000" }, { - "val" : "FBbt:00100313" + "val" : "FBbt:00100313", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -21827,7 +24598,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007330" + "val" : "FBbt:00007330", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67509" }, { @@ -21893,7 +24670,13 @@ "val" : "main body segment" } ], "xrefs" : [ { - "val" : "FBbt:00057001" + "val" : "FBbt:00057001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -21948,7 +24731,13 @@ }, { "val" : "NCIT:C32450" }, { - "val" : "UMLS:C1511770" + "val" : "UMLS:C1511770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Dense_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Dense_connective_tissue" } ], @@ -22039,7 +24828,13 @@ "val" : "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "coelom" @@ -22322,7 +25117,13 @@ "xrefs" : [ "MA:0002449" ] } ], "xrefs" : [ { - "val" : "EMAPA:37597" + "val" : "EMAPA:37597", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002449" } ], @@ -22480,7 +25281,13 @@ "xrefs" : [ { "val" : "CARO:0020000" }, { - "val" : "FBbt:00007276" + "val" : "FBbt:00007276", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -24085,7 +26892,13 @@ "meta" : { "definition" : { "val" : "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -24101,7 +26914,13 @@ "meta" : { "definition" : { "val" : "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -24409,7 +27228,7 @@ } }, { "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym", - "lbl" : "has_narrow_synonym", + "lbl" : "has narrow synonym", "type" : "PROPERTY", "propertyType" : "ANNOTATION", "meta" : { @@ -24528,22 +27347,18 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000007", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0002321" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0011115" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", - "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0017145" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000037", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000037", "pred" : "is_a", @@ -24714,6 +27529,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000076", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000066" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000076", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000077", "pred" : "is_a", @@ -24954,6 +27773,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000219" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000333", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", @@ -25034,6 +27857,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000540", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0019226" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000541", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000541", "pred" : "is_a", @@ -25378,6 +28205,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000566", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", "obj" : "http://purl.obolibrary.org/obo/CL_0000134" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000680", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000680", "pred" : "is_a", @@ -25716,6 +28547,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0007004", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", @@ -25760,10 +28595,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0011026", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", @@ -26050,7 +28881,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0032991" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005581", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "pred" : "http://purl.obolibrary.org/obo/RO_0002160", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005587", @@ -26420,6 +29251,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008015", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/GO_0003013" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0008150", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", + "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -27892,6 +30727,14 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_117571", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_117570" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_119089", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6231" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33317" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_131567", "pred" : "is_a", @@ -27916,10 +30759,22 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6236" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2301116" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33154" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "pred" : "is_a", @@ -27952,6 +30807,10 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33213", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6072" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33317", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33213" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_33511", "pred" : "is_a", @@ -28004,10 +30863,34 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_554915", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2759" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_55879", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_2301119" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_55885", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_6243" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6072", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6231", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_1206794" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6236", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_119089" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6237", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_55885" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_6243", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_55879" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_7711", "pred" : "is_a", @@ -28116,6 +30999,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0001579", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0001591", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0000052" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0001690", "pred" : "is_a", @@ -28188,6 +31075,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002198", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0002254", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001591" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002266", "pred" : "is_a", @@ -32808,6 +35699,13 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0001981" } ] + }, { + "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000076", + "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], + "restrictions" : [ { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002254" + } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000081", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -34702,6 +37600,13 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" } ] + }, { + "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", + "allValuesFromEdges" : [ { + "sub" : "http://purl.obolibrary.org/obo/GO_0005581", + "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062", "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], diff --git a/subsets/general_cell_types_upper_slim.obo b/subsets/general_cell_types_upper_slim.obo index e3520614d..9dc0c5130 100644 --- a/subsets/general_cell_types_upper_slim.obo +++ b/subsets/general_cell_types_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2025-12-17/subsets/general_cell_types_upper_slim.owl +data-version: cl/releases/2026-03-17/subsets/general_cell_types_upper_slim.owl idspace: dc http://purl.org/dc/elements/1.1/ idspace: foaf http://xmlns.com/foaf/0.1/ idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# @@ -7,7 +7,7 @@ idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: terms http://purl.org/dc/terms/ ontology: cl/subsets/general_cell_types_upper_slim -property_value: owl:versionInfo "2025-12-17" xsd:string +property_value: owl:versionInfo "2026-03-17" xsd:string [Term] id: BFO:0000002 @@ -78,21 +78,18 @@ property_value: skos:prefLabel "early embryonic cell (metazoa)" xsd:string id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] -comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset -synonym: "animal stem cell" EXACT [] +synonym: "animal stem cell" NARROW [] xref: CALOHA:TS-2086 xref: FMA:63368 xref: ZFA:0005957 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa relationship: RO:0002215 GO:0017145 ! capable of stem cell division property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000034" xsd:string {name="stem cell on CELLxGENE CellGuide"} @@ -119,6 +116,7 @@ xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 xref: ZFA:0009014 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell @@ -360,13 +358,18 @@ property_value: terms:description "Blood vessel endothelial cells, also known as [Term] id: CL:0000076 name: squamous epithelial cell +def: "An epithelial cell that has a flattened morphology." [] subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: CALOHA:TS-1249 xref: ZFA:0009039 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell +intersection_of: CL:0000066 ! epithelial cell +intersection_of: RO:0000053 PATO:0002254 ! has characteristic flattened +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: skos:prefLabel "squamous epithelial cell" xsd:string +property_value: terms:date "2025-12-16T15:56:39Z" xsd:dateTime [Term] id: CL:0000077 @@ -547,6 +550,7 @@ name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset subset: general_cell_types_upper_slim +subset: human_reference_atlas subset: human_subset subset: mouse_subset synonym: "muscle fiber" EXACT [] @@ -564,6 +568,7 @@ is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell relationship: RO:0002202 CL:0000056 ! develops from myoblast property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI +property_value: RO:0002175 NCBITaxon:9606 property_value: skos:prefLabel "muscle cell" xsd:string [Term] @@ -738,6 +743,7 @@ subset: mouse_subset xref: FMA:86667 xref: ZFA:0007086 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell @@ -869,6 +875,7 @@ subset: mouse_subset xref: BTO:0003217 xref: FMA:83377 xref: ZFA:0009249 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell @@ -1145,6 +1152,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009291 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell @@ -1575,6 +1583,7 @@ subset: human_subset subset: mouse_subset xref: ZFA:0007084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: BFO:0000002 +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell @@ -1641,7 +1650,6 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset is_a: BFO:0000002 -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002202 CL:0000034 ! develops from stem cell @@ -1713,6 +1721,7 @@ is_a: GO:0140096 ! catalytic activity, acting on a protein is_a: GO:0140101 ! catalytic activity, acting on a tRNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0000262 @@ -2024,6 +2033,7 @@ subset: goslim_yeast synonym: "molecular function" EXACT [] disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process +property_value: IAO:0000116 "This is the same as GO molecular function" xsd:string [Term] id: GO:0003824 @@ -2060,6 +2070,9 @@ synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 +union_of: GO:0032991 ! protein-containing complex +union_of: GO:0044423 ! virion component +union_of: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0008150 ! biological_process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI @@ -2108,7 +2121,8 @@ namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa +relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa +relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0005587 @@ -2836,6 +2850,7 @@ synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process +relationship: BFO:0000051 GO:0003674 ! has part molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI creation_date: 2012-09-19T15:05:24Z @@ -3264,10 +3279,10 @@ subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" -xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016746 @@ -3284,6 +3299,7 @@ xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurin xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" is_a: GO:0016740 ! transferase activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016755 @@ -3293,6 +3309,7 @@ def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) synonym: "transferase activity, transferring amino-acyl groups" EXACT [] xref: EC:2.3.2.- is_a: GO:0016746 ! acyltransferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0017145 @@ -3496,6 +3513,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] @@ -3504,6 +3522,7 @@ is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] @@ -3511,6 +3530,7 @@ id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:18391171] +subset: gocheck_do_not_annotate synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly @@ -3518,6 +3538,7 @@ is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI [Term] id: GO:0030054 @@ -3835,6 +3856,7 @@ is_a: GO:0005575 ! cellular_component disjoint_from: GO:0044423 ! virion component disjoint_from: GO:0110165 ! cellular anatomical structure relationship: BFO:0000051 PR:000000001 ! has part protein +property_value: IAO:0000116 "This is not covalently bonded, which conflicts with changes to the parent definition." xsd:string [Term] id: GO:0034101 @@ -3943,12 +3965,13 @@ def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which mel xref: Wikipedia:Melanosome is_a: GO:0048770 ! pigment granule relationship: BFO:0000050 CL:0000148 ! part of melanocyte +property_value: RO:0002161 NCBITaxon:6237 [Term] id: GO:0042592 name: homeostatic process namespace: biological_process -def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] +def: "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." [PMID:26265027] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse @@ -3959,6 +3982,7 @@ synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological_process +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31175" xsd:anyURI [Term] id: GO:0042644 @@ -4025,6 +4049,7 @@ id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon @@ -4037,6 +4062,7 @@ synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: BFO:0000050 CL:0000000 ! part of cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: skos:prefLabel "cell projection" xsd:string [Term] @@ -4976,15 +5002,16 @@ def: "A collagen trimer that forms networks." [PMID:21421911] is_a: BFO:0000004 is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer -intersection_of: BFO:0000050 GO:0098645 ! part of collagen network -relationship: BFO:0000050 GO:0098645 ! part of collagen network +intersection_of: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens +relationship: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens [Term] id: GO:0098643 -name: fibrillar collagen +name: fibrillar collagen complex namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175] synonym: "banded collagen fibril" EXACT [] +synonym: "fibrillar collagen" EXACT [] is_a: GO:0098644 ! complex of collagen trimers relationship: BFO:0000050 GO:0140152 ! part of collagenous component of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI @@ -5005,10 +5032,12 @@ property_value: skos:prefLabel "complex of collagen trimers" xsd:string [Term] id: GO:0098645 -name: collagen network +name: complex of network-forming collagens namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] +synonym: "collagen network" EXACT [] is_a: GO:0098644 ! complex of collagen trimers +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30938" xsd:anyURI [Term] id: GO:0098793 @@ -5084,6 +5113,8 @@ subset: goslim_pir synonym: "cellular anatomical entity" EXACT [] is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure +property_value: IAO:0000116 "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." xsd:string +property_value: IAO:0000116 "Overlaps with some cellular components from GO" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28978" xsd:anyURI @@ -5238,7 +5269,7 @@ id: GO:0140154 name: chicken-wire-like collagen network namespace: cellular_component def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942] -is_a: GO:0098645 ! collagen network +is_a: GO:0098645 ! complex of network-forming collagens relationship: BFO:0000050 GO:0140143 ! part of collagenous component of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI @@ -5383,6 +5414,21 @@ xref: GC_ID:1 is_a: NCBITaxon:117570 ! Teleostomi property_value: skos:prefLabel "Euteleostomi" xsd:string +[Term] +id: NCBITaxon:119089 +name: Chromadorea +namespace: ncbi_taxonomy +synonym: "Adenophorea" RELATED synonym [] +xref: GC_ID:1 +is_a: NCBITaxon:6231 ! Nematoda + +[Term] +id: NCBITaxon:1206794 +name: Ecdysozoa +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:33317 ! Protostomia + [Term] id: NCBITaxon:131567 name: cellular organisms @@ -5475,6 +5521,20 @@ xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2759 ! Eukaryota +[Term] +id: NCBITaxon:2301116 +name: Rhabditina +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:6236 ! Rhabditida + +[Term] +id: NCBITaxon:2301119 +name: Rhabditomorpha +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:2301116 ! Rhabditina + [Term] id: NCBITaxon:2759 name: Eukaryota @@ -5491,6 +5551,22 @@ xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: skos:prefLabel "Eukaryota" xsd:string +[Term] +id: NCBITaxon:28009 +name: Choanoflagellata +namespace: ncbi_taxonomy +synonym: "Choanoflagellatea" RELATED synonym [] +synonym: "choanoflagellates" EXACT genbank_common_name [] +synonym: "choanoflagellates" RELATED blast_name [] +synonym: "Choanoflagellida" RELATED synonym [] +synonym: "Choanomonada" RELATED synonym [] +synonym: "Choanozoa" RELATED synonym [] +xref: GC_ID:1 +xref: PMID:27765632 +is_a: NCBITaxon:33154 ! Opisthokonta +disjoint_from: NCBITaxon:33208 ! Metazoa +disjoint_from: NCBITaxon:4751 ! Fungi + [Term] id: NCBITaxon:314146 name: Euarchontoglires @@ -5575,6 +5651,14 @@ xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa property_value: skos:prefLabel "Bilateria" xsd:string +[Term] +id: NCBITaxon:33317 +name: Protostomia +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:33213 ! Bilateria +disjoint_from: NCBITaxon:33511 ! Deuterostomia + [Term] id: NCBITaxon:33511 name: Deuterostomia @@ -5694,6 +5778,20 @@ xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota +[Term] +id: NCBITaxon:55879 +name: Rhabditoidea +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:2301119 ! Rhabditomorpha + +[Term] +id: NCBITaxon:55885 +name: Peloderinae +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:6243 ! Rhabditidae + [Term] id: NCBITaxon:6072 name: Eumetazoa @@ -5702,6 +5800,41 @@ xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: skos:prefLabel "Eumetazoa" xsd:string +[Term] +id: NCBITaxon:6231 +name: Nematoda +namespace: ncbi_taxonomy +synonym: "Nemata" RELATED synonym [] +synonym: "nematode" EXACT OMO:0003003 [] +synonym: "nematodes" EXACT genbank_common_name [] +synonym: "nematodes" RELATED blast_name [] +synonym: "roundworm" EXACT OMO:0003003 [] +synonym: "roundworms" EXACT OMO:0003003 [] +xref: GC_ID:1 +is_a: NCBITaxon:1206794 ! Ecdysozoa + +[Term] +id: NCBITaxon:6236 +name: Rhabditida +namespace: ncbi_taxonomy +synonym: "Strongylida" RELATED synonym [] +xref: GC_ID:1 +is_a: NCBITaxon:119089 ! Chromadorea + +[Term] +id: NCBITaxon:6237 +name: Caenorhabditis +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:55885 ! Peloderinae + +[Term] +id: NCBITaxon:6243 +name: Rhabditidae +namespace: ncbi_taxonomy +xref: GC_ID:1 +is_a: NCBITaxon:55879 ! Rhabditoidea + [Term] id: NCBITaxon:7711 name: Chordata @@ -5976,6 +6109,14 @@ subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality +[Term] +id: PATO:0001591 +name: curvature +namespace: quality +def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] +subset: attribute_slim +is_a: PATO:0000052 ! shape + [Term] id: PATO:0001690 name: contractile @@ -6131,6 +6272,18 @@ is_a: PATO:0001018 ! physical quality property_value: terms:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-03-15T04:35:27Z +[Term] +id: PATO:0002254 +name: flattened +namespace: quality +def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] +comment: Becoming flat but not necessarily completely flat. +subset: value_slim +synonym: "compressed" RELATED [] +is_a: PATO:0001591 ! curvature +property_value: terms:contributor https://orcid.org/0000-0002-2061-091X +creation_date: 2010-08-16T03:59:34Z + [Term] id: PATO:0002266 name: 3-D shape @@ -12001,7 +12154,7 @@ xref: NCIT:C32339 xref: NIF_Subcellular:sao7547390221 is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: RO:0002473 GO:0005581 ! composed primarily of collagen trimer -relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen +relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen complex property_value: seeAlso UBERON:0007377 property_value: skos:prefLabel "collection of collagen fibrils" xsd:string diff --git a/subsets/general_cell_types_upper_slim.owl b/subsets/general_cell_types_upper_slim.owl index e4b044fa4..566357716 100644 --- a/subsets/general_cell_types_upper_slim.owl +++ b/subsets/general_cell_types_upper_slim.owl @@ -14,8 +14,8 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - - 2025-12-17 + + 2026-03-17 @@ -245,7 +245,6 @@ WHERE { An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has narrow synonym - has_narrow_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/19 @@ -2481,14 +2480,7 @@ Each of these 3 primitives can be composed to yield a cross-product of different - - - - - - - @@ -2505,13 +2497,12 @@ Stem cells have numerous potential applications in medicine, including the treat CALOHA:TS-2086 FMA:63368 ZFA:0005957 - animal stem cell + animal stem cell - This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. stem cell https://cellxgene.cziscience.com/cellguide/CL_0000034 stem cell @@ -2618,6 +2609,7 @@ Stem cells have numerous potential applications in medicine, including the treat + @@ -3413,7 +3405,26 @@ Blood vessel endothelial cells are sensitive to various stimuli, including shear + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -3962,6 +3973,7 @@ In addition to melanin production, melanocytes also engage in a variety of other A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -3975,6 +3987,7 @@ In addition to melanin production, melanocytes also engage in a variety of other + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -4473,6 +4486,7 @@ In addition to their role in oxygen transport, erythrocytes also play a key role + @@ -4817,6 +4831,7 @@ Clinically and in research, stromal cells often draw attention due to their inte + @@ -5940,6 +5955,7 @@ Apart from platelet production, megakaryocytes are involved in several other fun + @@ -7241,6 +7257,7 @@ The balance between cell proliferation and differentiation in embryonic cells is + @@ -7431,7 +7448,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -7613,6 +7629,7 @@ Disorders or aberrations in the development or migration of the neural crest cel Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. https://github.com/geneontology/go-ontology/issues/22192 https://github.com/geneontology/go-ontology/issues/25493 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.12 MetaCyc:PEPTIDYLTRANSFERASE-RXN Reactome:R-HSA-156912 @@ -8500,6 +8517,7 @@ Disorders or aberrations in the development or migration of the neural crest cel A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. + This is the same as GO molecular function molecular function molecular_function GO:0003674 @@ -8562,6 +8580,15 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + @@ -8681,10 +8708,16 @@ Disorders or aberrations in the development or migration of the neural crest cel - + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component @@ -10469,6 +10502,12 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. https://github.com/geneontology/go-ontology/issues/24968 2012-09-19T15:05:24Z @@ -10657,6 +10696,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. @@ -10705,6 +10768,16 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + @@ -10775,6 +10848,16 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + @@ -10845,6 +10928,16 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + @@ -10881,6 +10974,70 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. @@ -11535,10 +11692,10 @@ Disorders or aberrations in the development or migration of the neural crest cel Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + https://github.com/geneontology/go-ontology/issues/30193 EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 - Reactome:R-HSA-5333607 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function @@ -11573,12 +11730,6 @@ Disorders or aberrations in the development or migration of the neural crest cel Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 - - - - Reactome:R-HSA-5333607 - GSSeH combines with bGalNAc derivative to form GSSebGalNac - @@ -11600,6 +11751,7 @@ Disorders or aberrations in the development or migration of the neural crest cel Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 @@ -11650,6 +11802,7 @@ Disorders or aberrations in the development or migration of the neural crest cel Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function @@ -12226,12 +12379,14 @@ Disorders or aberrations in the development or migration of the neural crest cel A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 https://github.com/geneontology/go-ontology/issues/26279 cell projection organisation biological_process cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 + cell projection organization @@ -12281,10 +12436,12 @@ Disorders or aberrations in the development or migration of the neural crest cel Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 formation of a cell surface projection biological_process cell projection biogenesis GO:0030031 + cell projection assembly @@ -13133,6 +13290,7 @@ Disorders or aberrations in the development or migration of the neural crest cel A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + This is not covalently bonded, which conflicts with changes to the parent definition. macromolecular complex macromolecule complex protein containing complex @@ -13512,13 +13670,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. + Wikipedia:Melanosome cellular_component GO:0042470 @@ -13538,7 +13713,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - Any biological process involved in the maintenance of an internal steady state. + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + https://github.com/geneontology/go-ontology/issues/31175 homeostasis activation of homeostatic process inhibition of homeostatic process @@ -13555,9 +13731,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - Any biological process involved in the maintenance of an internal steady state. - GOC:jl - ISBN:0395825172 + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + PMID:26265027 @@ -13665,6 +13840,16 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + @@ -13773,11 +13958,13 @@ Disorders or aberrations in the development or migration of the neural crest cel A prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 cell process cellular process cellular projection cellular_component GO:0042995 + @@ -16382,9 +16569,10 @@ Disorders or aberrations in the development or migration of the neural crest cel https://github.com/geneontology/go-ontology/issues/29474 https://github.com/geneontology/go-ontology/issues/30146 banded collagen fibril + fibrillar collagen cellular_component GO:0098643 - fibrillar collagen + fibrillar collagen complex fibrillar collagen @@ -16449,9 +16637,11 @@ Disorders or aberrations in the development or migration of the neural crest cel A supramolecular complex that consists of collagen triple helices associated to form a network. + https://github.com/geneontology/go-ontology/issues/30938 + collagen network cellular_component GO:0098645 - collagen network + complex of network-forming collagens @@ -16665,6 +16855,9 @@ Disorders or aberrations in the development or migration of the neural crest cel A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes. + Overlaps with some cellular components from GO https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 https://github.com/geneontology/go-ontology/issues/28978 @@ -17458,6 +17651,37 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + GC_ID:1 + ncbi_taxonomy + Adenophorea + NCBITaxon:119089 + Chromadorea + + + + + Adenophorea + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:1206794 + Ecdysozoa + + + + @@ -17682,6 +17906,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:2301116 + Rhabditina + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:2301119 + Rhabditomorpha + + + + @@ -17739,6 +17987,63 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + GC_ID:1 + PMID:27765632 + choanoflagellates + ncbi_taxonomy + Choanoflagellatea + Choanoflagellida + Choanomonada + Choanozoa + choanoflagellates + NCBITaxon:28009 + Choanoflagellata + + + + + choanoflagellates + + + + + + Choanoflagellatea + + + + + + Choanoflagellida + + + + + + Choanomonada + + + + + + Choanozoa + + + + + + choanoflagellates + + + + + @@ -17929,6 +18234,19 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:33317 + Protostomia + + + + @@ -18185,6 +18503,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:55879 + Rhabditoidea + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:55885 + Peloderinae + + + + @@ -18198,6 +18540,103 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + GC_ID:1 + nematode + nematodes + roundworm + roundworms + ncbi_taxonomy + Nemata + nematodes + NCBITaxon:6231 + Nematoda + + + + + nematode + + + + + + nematodes + + + + + + roundworm + + + + + + roundworms + + + + + + Nemata + + + + + + nematodes + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + Strongylida + NCBITaxon:6236 + Rhabditida + + + + + Strongylida + + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:6237 + Caenorhabditis + + + + + + + + + GC_ID:1 + ncbi_taxonomy + NCBITaxon:6243 + Rhabditidae + + + + @@ -18829,6 +19268,25 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + quality + PATO:0001591 + + curvature + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + WordNet:WordNet + + + + @@ -19170,6 +19628,29 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + + 2010-08-16T03:59:34Z + quality + compressed + PATO:0002254 + + Becoming flat but not necessarily completely flat. + flattened + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + PATOC:CVS + + + + @@ -21588,7 +22069,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -21599,14 +22080,14 @@ Disorders or aberrations in the development or migration of the neural crest cel membrane organ membrane organ - + - + FMA-def @@ -22375,7 +22856,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -22417,14 +22898,14 @@ Disorders or aberrations in the development or migration of the neural crest cel gastrula stage gastrula stage - + - + BILS @@ -22909,15 +23390,15 @@ Disorders or aberrations in the development or migration of the neural crest cel - + - - + + A fluid that is composed of blood plasma and erythrocytes. @@ -22956,34 +23437,34 @@ Disorders or aberrations in the development or migration of the neural crest cel blood blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -24795,7 +25276,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. AAO:0000137 BILA:0000036 @@ -24830,14 +25311,14 @@ Disorders or aberrations in the development or migration of the neural crest cel ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -24877,7 +25358,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. AAO:0000139 BILA:0000038 @@ -24912,14 +25393,14 @@ Disorders or aberrations in the development or migration of the neural crest cel http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -24960,7 +25441,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The middle germ layer of the embryo, between the endoderm and ectoderm. AAO:0000304 @@ -25000,14 +25481,14 @@ Disorders or aberrations in the development or migration of the neural crest cel mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + - + Bgee:AN @@ -25175,7 +25656,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -25240,14 +25721,14 @@ Disorders or aberrations in the development or migration of the neural crest cel https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb - + - + MA @@ -25659,7 +26140,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -25709,14 +26190,14 @@ Disorders or aberrations in the development or migration of the neural crest cel http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -25776,7 +26257,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. @@ -25821,7 +26302,7 @@ Disorders or aberrations in the development or migration of the neural crest cel central nervous system central nervous system - + @@ -25835,7 +26316,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Bgee:AN @@ -26206,7 +26687,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -26231,14 +26712,14 @@ Disorders or aberrations in the development or migration of the neural crest cel mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -26370,13 +26851,13 @@ Disorders or aberrations in the development or migration of the neural crest cel - + - + Skeletal element that is composed of bone tissue. @@ -26418,14 +26899,14 @@ Disorders or aberrations in the development or migration of the neural crest cel bone element bone element - + - + VSAO-modified @@ -26579,7 +27060,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + A tube extending from the mouth to the anus. @@ -26617,14 +27098,14 @@ Disorders or aberrations in the development or migration of the neural crest cel digestive tract digestive tract - + - + NCBIBook:NBK10107 @@ -27182,8 +27663,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + @@ -27196,7 +27677,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -27250,34 +27731,34 @@ Disorders or aberrations in the development or migration of the neural crest cel blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -28149,7 +28630,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -28185,14 +28666,14 @@ Disorders or aberrations in the development or migration of the neural crest cel coelemic cavity lumen coelemic cavity lumen - + - + definitional @@ -28288,8 +28769,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + @@ -28339,11 +28820,11 @@ Disorders or aberrations in the development or migration of the neural crest cel notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -28362,13 +28843,13 @@ Disorders or aberrations in the development or migration of the neural crest cel - + ZFA - + EHDAA2 @@ -28409,7 +28890,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. mesodermal cluster @@ -28447,7 +28928,7 @@ Disorders or aberrations in the development or migration of the neural crest cel somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -28460,7 +28941,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + ZFA @@ -28578,16 +29059,16 @@ Disorders or aberrations in the development or migration of the neural crest cel - - - + + + - + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. AAO:0010578 BTO:0001764 @@ -28620,45 +29101,45 @@ Disorders or aberrations in the development or migration of the neural crest cel http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + BTO - + PMID:11523831 - + PMID:11523831 @@ -29018,8 +29499,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + Anatomical system that is involved in the production of hematopoietic cells. AAO:0011002 @@ -29059,24 +29540,24 @@ Disorders or aberrations in the development or migration of the neural crest cel hematopoietic system hematopoietic system - + - + - + FMA - + definitional @@ -29397,7 +29878,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -29416,7 +29897,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. AAO:0011086 EFO:0001982 @@ -29439,14 +29920,14 @@ Disorders or aberrations in the development or migration of the neural crest cel presomitic mesoderm presomitic mesoderm - + - + Bgee:AN @@ -29602,8 +30083,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. AAO:0011072 BTO:0001765 @@ -29632,24 +30113,24 @@ Disorders or aberrations in the development or migration of the neural crest cel neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + Wikipedia - + Bgee:AN @@ -29695,7 +30176,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. AAO:0010568 EFO:0003515 @@ -29721,7 +30202,7 @@ Disorders or aberrations in the development or migration of the neural crest cel paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -29734,7 +30215,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Bgee:AN @@ -29781,7 +30262,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -29820,7 +30301,7 @@ Disorders or aberrations in the development or migration of the neural crest cel lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -29833,7 +30314,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + EHDAA2 VHOG @@ -29884,15 +30365,15 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. AAO:0011044 @@ -29909,15 +30390,15 @@ Disorders or aberrations in the development or migration of the neural crest cel heart primordium heart primordium - + - + - + @@ -29930,19 +30411,19 @@ Disorders or aberrations in the development or migration of the neural crest cel - + ZFA - + ZFA - + XAO @@ -29971,8 +30452,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. AAO:0010571 AEO:0000212 @@ -29996,11 +30477,11 @@ Disorders or aberrations in the development or migration of the neural crest cel sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -30019,13 +30500,13 @@ Disorders or aberrations in the development or migration of the neural crest cel - + VHOG:0000680 - + ZFA @@ -30278,7 +30759,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults EHDAA:251 @@ -30293,14 +30774,14 @@ Disorders or aberrations in the development or migration of the neural crest cel intraembryonic coelom intraembryonic coelom - + - + Wikipedia @@ -30658,8 +31139,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. XAO:0004185 first heart field @@ -30671,24 +31152,24 @@ Disorders or aberrations in the development or migration of the neural crest cel primary heart field primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -30741,7 +31222,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + An epithelial tube that will give rise to the mature heart. AAO:0010411 EFO:0003526 @@ -30760,14 +31241,14 @@ Disorders or aberrations in the development or migration of the neural crest cel heart tube heart tube - + - + ZFA-modified @@ -31482,7 +31963,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. AAO:0011129 TAO:0001890 @@ -31496,14 +31977,14 @@ Disorders or aberrations in the development or migration of the neural crest cel skeletal element skeletal element - + - + VSAO @@ -31531,7 +32012,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -31564,14 +32045,14 @@ Disorders or aberrations in the development or migration of the neural crest cel articular system articular system - + - + FMA @@ -32269,7 +32750,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -32285,14 +32766,14 @@ Disorders or aberrations in the development or migration of the neural crest cel trunk mesenchyme trunk mesenchyme - + - + EHDAA2 @@ -32410,7 +32891,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. EHDAA2:0001512 EHDAA:424 @@ -32428,14 +32909,14 @@ Disorders or aberrations in the development or migration of the neural crest cel primitive heart tube primitive heart tube - + - + ZFA @@ -32595,7 +33076,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -32605,7 +33086,7 @@ Disorders or aberrations in the development or migration of the neural crest cel developing mesenchymal condensation developing mesenchymal condensation - + @@ -32624,7 +33105,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + AEO-modified-relation @@ -32720,7 +33201,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB EHDAA2:0001278 @@ -32734,7 +33215,7 @@ Disorders or aberrations in the development or migration of the neural crest cel notochordal plate notochordal plate - + @@ -32747,7 +33228,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + EHDAA2 @@ -32776,7 +33257,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -32793,14 +33274,14 @@ Disorders or aberrations in the development or migration of the neural crest cel notochordal process notochordal process - + - + EHDAA2 @@ -33674,7 +34155,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -33700,7 +34181,7 @@ Disorders or aberrations in the development or migration of the neural crest cel presumptive paraxial mesoderm presumptive paraxial mesoderm - + @@ -33716,7 +34197,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + https://github.com/obophenotype/uberon/issues/1277 @@ -33793,7 +34274,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -33801,7 +34282,7 @@ Disorders or aberrations in the development or migration of the neural crest cel dense mesenchyme tissue dense mesenchyme tissue - + @@ -33814,7 +34295,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + AEO @@ -33880,7 +34361,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -33900,14 +34381,14 @@ Disorders or aberrations in the development or migration of the neural crest cel layer of synovial tissue layer of synovial tissue - + - + BTO @@ -34181,7 +34662,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -34198,14 +34679,14 @@ Disorders or aberrations in the development or migration of the neural crest cel vascular system vascular system - + - + MA @@ -34235,7 +34716,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -34251,14 +34732,14 @@ Disorders or aberrations in the development or migration of the neural crest cel entire embryonic mesenchyme entire embryonic mesenchyme - + - + EHDAA2 @@ -34314,7 +34795,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme @@ -34322,14 +34803,14 @@ Disorders or aberrations in the development or migration of the neural crest cel trunk paraxial mesoderm trunk paraxial mesoderm - + - + EHDAA2 @@ -34424,7 +34905,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -34434,14 +34915,14 @@ Disorders or aberrations in the development or migration of the neural crest cel anterior lateral plate mesoderm anterior lateral plate mesoderm - + - + ZFA @@ -34639,7 +35120,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -34649,14 +35130,14 @@ Disorders or aberrations in the development or migration of the neural crest cel microcirculatory vessel microcirculatory vessel - + - + ZFA @@ -34681,8 +35162,8 @@ Disorders or aberrations in the development or migration of the neural crest cel - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. FMA:23879 SCTID:129140006 @@ -34694,11 +35175,11 @@ Disorders or aberrations in the development or migration of the neural crest cel subdivision of skeleton subdivision of skeleton - + - + @@ -34711,13 +35192,13 @@ Disorders or aberrations in the development or migration of the neural crest cel - + UBERONREF:0000003 - + VSAO @@ -34811,7 +35292,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -34822,7 +35303,7 @@ Disorders or aberrations in the development or migration of the neural crest cel http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton postcranial axial skeletal system - + @@ -34835,7 +35316,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + cjm @@ -35788,7 +36269,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + @@ -35811,7 +36292,7 @@ Disorders or aberrations in the development or migration of the neural crest cel entire extraembryonic component entire extraembryonic component - + @@ -35824,7 +36305,7 @@ Disorders or aberrations in the development or migration of the neural crest cel - + AEO @@ -36332,14 +36813,14 @@ Disorders or aberrations in the development or migration of the neural crest cel - + - + definitional - + @@ -36527,6 +37008,34 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -36621,6 +37130,34 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -36635,6 +37172,40 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -36767,6 +37338,30 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + @@ -36949,6 +37544,34 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -36963,6 +37586,62 @@ Disorders or aberrations in the development or migration of the neural crest cel + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/subsets/general_cell_types_upper_slim.tsv b/subsets/general_cell_types_upper_slim.tsv index f68d1585f..41ecc759a 100644 --- a/subsets/general_cell_types_upper_slim.tsv +++ b/subsets/general_cell_types_upper_slim.tsv @@ -312,9 +312,9 @@ http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer -http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen +http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers -http://purl.obolibrary.org/obo/GO_0098645 collagen network +http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling @@ -347,13 +347,18 @@ http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_10090 Mus musculus http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi +http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea +http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria +http://purl.obolibrary.org/obo/NCBITaxon_2301116 Rhabditina +http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota +http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda @@ -362,6 +367,7 @@ http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria +http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_34346 Schizosaccharomycetales @@ -375,7 +381,13 @@ http://purl.obolibrary.org/obo/NCBITaxon_4894 Schizosaccharomycetaceae http://purl.obolibrary.org/obo/NCBITaxon_4895 Schizosaccharomyces http://purl.obolibrary.org/obo/NCBITaxon_4896 Schizosaccharomyces pombe http://purl.obolibrary.org/obo/NCBITaxon_554915 Amoebozoa +http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea +http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa +http://purl.obolibrary.org/obo/NCBITaxon_6231 Nematoda +http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida +http://purl.obolibrary.org/obo/NCBITaxon_6237 Caenorhabditis +http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata @@ -403,6 +415,7 @@ http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0001579 contractility +http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0001873 cylindrical @@ -419,6 +432,7 @@ http://purl.obolibrary.org/obo/PATO_0002045 dendritic http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance +http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002318 superelliptic diff --git a/subsets/kidney_upper_slim.json b/subsets/kidney_upper_slim.json index 4f9e8e922..1ad1a6ba4 100644 --- a/subsets/kidney_upper_slim.json +++ b/subsets/kidney_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2025-12-17" + "val" : "2026-03-17" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2025-12-17/subsets/kidney_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2026-03-17/subsets/kidney_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -43,7 +43,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { - "val" : "FBbt:00007002" + "val" : "FBbt:00007002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:68646" }, { @@ -59,7 +65,13 @@ }, { "val" : "XAO:0003012" }, { - "val" : "ZFA:0009000" + "val" : "ZFA:0009000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -77,7 +89,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009002" + "val" : "ZFA:0009002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -93,10 +111,9 @@ "val" : "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, - "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { - "pred" : "hasExactSynonym", + "pred" : "hasNarrowSynonym", "val" : "animal stem cell" } ], "xrefs" : [ { @@ -104,7 +121,13 @@ }, { "val" : "FMA:63368" }, { - "val" : "ZFA:0005957" + "val" : "ZFA:0005957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -114,7 +137,13 @@ "val" : "Stem cells are a unique type of cell that has the remarkable ability to divide and develop into many different types of cells in the body. These cells are undifferentiated, meaning they haven't yet developed into a specific cell type, and they can renew themselves through cell division. As a result, stem cells have the potential to replace damaged or diseased cells in the body, making them a valuable tool in medicine and research.\nThere are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos and can develop into any type of cell in the body. Adult stem cells, on the other hand, are found in various tissues and organs throughout the body and can only develop into certain types of cells.\nStem cells have numerous potential applications in medicine, including the treatment of various diseases and the repair of damaged tissues. For example, they could be used to replace damaged heart tissue after a heart attack or to repair spinal cord injuries. Stem cells also have potential uses in drug development and disease research, as they can be used to model diseases and test potential therapies in vitro.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stem cell" @@ -156,7 +185,13 @@ }, { "val" : "VHOG:0001485" }, { - "val" : "ZFA:0009014" + "val" : "ZFA:0009014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -166,7 +201,13 @@ "val" : "Hematopoietic stem cells (HSCs) are multipotent cells, capable of differentiating into a wide variety of specialized blood cells. During embryonic development hematopoietic stem cells emerge from the hemogenic endothelium, a specialized subset of endothelial cells with hematopoietic potential. HSCs can be found in several organs, in particular in bone marrow, as well as peripheral blood and umbilical cord blood.\nThese stem cells have a distinctive ability to self-renew, and to differentiate into all lymphoid and myeloid cell types that together form the blood and immune systems including erythrocytes (red blood cells), leukocytes (white blood cells), and platelets. Their primary function is to ensure the continuous replenishment of the blood and immune system throughout an individual's lifespan.\nIn response to various signals, hematopoietic stem cells can either remain dormant or actively divide and differentiate. Under normal conditions, the majority of these stem cells exist in a quiescent (inactive) state, making them somewhat resistant to chemotherapy or radiation therapy in the treatment of various diseases such as leukemia. However, when the body encounters stress such as infection, bleeding, or disease, hematopoietic stem cells can rapidly become active in order to replenish the affected cells and maintain homeostasis.\nFurthermore, hematopoietic stem cells are extremely important in the field of regenerative medicine and transplantation. Regarded as lifesaving in the field of oncology, they are often extracted, purified, and reinfused back into the same (autologous transplantation) or different (allogeneic transplantation) individuals to reestablish a healthy, functioning hematopoietic and immune system after high-dose chemotherapy or to replace dysfunctional bone marrow. Understanding and manipulating the behavior of these stem cells has immense potential in treating various blood disorders, autoimmune diseases, and cancers.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000037", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "hematopoietic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "hematopoietic stem cell" @@ -206,14 +247,26 @@ "xrefs" : [ { "val" : "BTO:0004911" }, { - "val" : "ZFA:0009015" + "val" : "ZFA:0009015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Erythroid progenitor cells play a key role in the hematopoietic system, specifically in the process of erythropoiesis – the production of red blood cells (erythrocytes). Found within the bone marrow, these cells are dedicated precursors to erythrocytes, and ensue in the hematopoietic lineage from multipotent progenitors. They represent a transitional cell type that bridges the gap between the early-stage erythroid precursors and the maturing red blood cell population.\nThe earliest committed erythroid progenitor cell is thought to be the burst-forming unit-erythroid (BFU-E) cell, which after several cell divisions gives rise to another erythroid progenitor, the colony-forming unit-erythroid (CFU-E) cell. \nErythroid progenitor cells are primarily responsible for responding to the demand for new red blood cells during conditions of physiological stress like infection, blood loss, or illness. This responsive behavior is regulated by a glycoprotein hormone known as erythropoietin, which is produced by the kidneys. Erythropoietin interacts with the receptors on the erythroid progenitor cells, prompting them to proliferate and differentiate into erythroblasts. The erythroblasts then further mature, eventually producing new, functional red cells.\nThe role of erythroid progenitor cells extends beyond their main function of erythrocyte production, as they also participate in maintaining the balance of iron in the body. Upon erythroid differentiation, they increase their uptake of transferrin-bound iron for hemoglobin synthesis, a vital component of red blood cells which allows them to transport oxygen. A deficiency or excess of erythroid progenitor cells can lead to extensive health issues such as anemia or polycythemia respectively, emphasizing their crucial role in human health.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythroid progenitor cell" @@ -231,7 +284,13 @@ "comments" : [ "Originally this term had some plant germ line cell children." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { - "val" : "ZFA:0009016" + "val" : "ZFA:0009016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -264,7 +323,13 @@ "xrefs" : [ { "val" : "FMA:84789" }, { - "val" : "ZFA:0009020" + "val" : "ZFA:0009020", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -320,7 +385,13 @@ "xrefs" : [ { "val" : "BTO:0004730" }, { - "val" : "ZFA:0009021" + "val" : "ZFA:0009021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -330,7 +401,13 @@ "val" : "The common myeloid progenitor (CMP) is a multipotent cell that serves as a crucial intermediary within the overall framework of hematopoietic cell differentiation, which is the process of blood cell production. This part of the hematopoiesis process leads to the formation of myeloid lineage cells, which includes granulocytes (neutrophils, eosinophils, and basophils), monocytes, erythrocytes (red blood cells), and megakaryocytes (platelet-forming cells). \nThe primary function of common myeloid progenitors is differentiation and proliferation into various types of mature blood cells, thereby providing a critical contribution to maintaining homeostasis within the body's immune and circulatory systems. Single-cell analyses have shown that the CMP cell population is heterogeneous with at least two distinct subpopulations, characterized by different cell surface markers and likely already committed to downstream differentiation into either the granulocyte/macrophage lineage or the megakaryocyte/erythrocyte lineage-restricted progenitor. \nThe destiny of a CMP is influenced by numerous cytokines and growth factors in its environment that promote differentiation along specific lineages. For example, IL-3 and GM-CSF stimulate the production of eosinophils, which are essential for the body’s defense against allergens and help fight fungal and parasitic infections. \nBy being able to differentiate into a wide range of different immune cells, common myeloid progenitors play a crucial role in the body's ability to respond to injuries, infections, and other physiological challenges.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "common myeloid progenitor on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "common myeloid progenitor" @@ -370,7 +447,13 @@ "val" : "megakaryocyte/erythroid progenitor cell" } ], "xrefs" : [ { - "val" : "ZFA:0009022" + "val" : "ZFA:0009022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -380,7 +463,13 @@ "val" : "The megakaryocyte-erythroid progenitor (MEP) cell belongs to the multipotent hematopoietic progenitor cells, which can give rise to multiple different cell types. They are found in the bone marrow, the primary organ where new blood cells are generated. MEPs are specially programmed to develop into two distinct blood cell lineages, namely megakaryocytes, which go on to produce platelets for blood clotting, and the erythroid lineage which consists of red blood cells responsible for oxygen transport in the body.\nThe MEP cells are the result of a decision-making process within the hematopoietic stem cell population. Hematopoietic stem cell can differentiate into multiple types of progenitor cells, including myeloid progenitor cells. A further subdivision within this myeloid lineage generates the MEP cells. Therefore, these megakaryocyte-erythroid progenitors represent a key juncture between hematopoietic stem cells and mature blood cell types in the myeloid lineage.\nMegakaryocyte-erythroid progenitor cells play a crucial role in the homeostasis of some of the most crucial constituents of blood. The megakaryocytes produced from these bipotent progenitor cells contribute to hemostasis by producing platelets - small anucleated fragments that are pivotal for blood clotting and preventing bleeding. Similarly, the erythroid lineage from MEP cells gives rise to erythrocytes, which harbor hemoglobin, the molecule that transports oxygen from lungs to every nook and corner of the body. An imbalance or malfunction in MEP function thus can significantly impact human health, leading to diseases like thrombocytopenia or anemia.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000050", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte-erythroid progenitor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "megakaryocyte-erythroid progenitor cell" @@ -405,7 +494,13 @@ }, { "val" : "MESH:D039901" }, { - "val" : "ZFA:0009024" + "val" : "ZFA:0009024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -427,13 +522,25 @@ }, { "val" : "CALOHA:TS-0650" }, { - "val" : "FBbt:00005083" + "val" : "FBbt:00005083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:70335" }, { "val" : "VHOG:0001529" }, { - "val" : "ZFA:0009025" + "val" : "ZFA:0009025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -462,7 +569,13 @@ }, { "val" : "VHOG:0001482" }, { - "val" : "ZFA:0009026" + "val" : "ZFA:0009026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -493,13 +606,25 @@ }, { "val" : "CARO:0000077" }, { - "val" : "FBbt:00000124" + "val" : "FBbt:00000124", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:66768" }, { "val" : "WBbt:0003672" }, { - "val" : "ZFA:0009034" + "val" : "ZFA:0009034", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -523,14 +648,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009372" + "val" : "ZFA:0009372", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Duct epithelial cells are distinctly specialized cells that predominantly form the lining of glandular ducts. These cells play a crucial role in the secretion, absorption, and transport of fluids depending on the organ they inhabit. They are typically organized in a tubular structure, forming collectively the conduit for the transport of substances. These cells exhibit tight junctions, enabling the careful regulation of the passage of substances and ensuring that no unwanted particles seep through. They are predominantly characterized by their polarized nature, having distinct apical and basolateral surfaces that support its functions of secretion and absorption. The apical surface, exposed to the duct lumen, is specialized for secretion and interaction with the luminal environment, while the basolateral surface is oriented towards the underlying tissue, facilitating interactions with neighboring cells and the extracellular matrix.\nThe ducts serve as the bridge between the gland and the site of secretion, allowing the substances produced by the gland to exit into the body. Thus, duct epithelial cells have a sweeping role in various physiological functions, ranging from defense against pathogens in the respiratory and digestive tracts, to secretion of digestive enzymes, to milk production in mammary glands.\nAs a result of their specialized function, any impairment in the function of duct epithelial cells to function properly often leads to certain diseases or disorders. Studies have identified potential correlation between malfunctioning duct epithelial cells and conditions such as cystic fibrosis, chronic obstructive pulmonary disease, and certain cancers, particularly breast and pancreatic.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000068" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000068", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "duct epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -544,7 +681,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009036" + "val" : "ZFA:0009036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -554,7 +697,13 @@ "val" : "Blood vessel endothelial cells, also known as vascular endothelial cells, form the delicate inner lining of the complex circulatory system, including arteries and veins. These cells form a single, continuous monolayer inside every blood vessel, acting as a crucial biomolecular barrier between the blood, and the rest of the body tissues. They perform various fundamental biological functions, ranging from maintenance of vessel integrity to blood clotting regulation. Additionally, they control the transportation of fluids, molecules, and blood particulate matter from and into the bloodstream.\nOne of the primary functions of blood vessel endothelial cells is to maintain vascular homeostasis - a stable environment within the blood vessels. They accomplish this through several methods: they control vasomotor tone, i.e. the degree of contraction and dilation of blood vessels, by secreting vasoactive substances such as nitric oxide and endothelin; mediate responses to inflammatory stimuli; and they also regulate angiogenesis, the process of new blood vessel formations. Blood vessel endothelial cells play a significant role in preventing blood clot formation by generating a slick, non-thrombogenic surface that disallows platelets or coagulant proteins from adhering to it.\nBlood vessel endothelial cells are sensitive to various stimuli, including shear stress caused by blood flow, and they can respond by altering their morphology, function, and gene expression. This ability to adapt enables blood vessels to remodel and ensure the adequate delivery of nutrients and oxygen to all tissues, regardless of physiological demand variations. Conversely, endothelial dysfunction, often associated with a reduction in the bioavailability of endothelium-derived nitric oxide, can lead to the development of pathological conditions such as atherosclerosis, hypertension, diabetes mellitus, and even aging-related diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000071", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "blood vessel endothelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "blood vessel endothelial cell" @@ -578,7 +727,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0009038" + "val" : "ZFA:0009038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -593,13 +748,25 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "definition" : { + "val" : "An epithelial cell that has a flattened morphology." + }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" }, { - "val" : "ZFA:0009039" + "val" : "ZFA:0009039", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/date", + "val" : "2025-12-16T15:56:39Z" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "squamous epithelial cell" } ] @@ -622,7 +789,13 @@ "xrefs" : [ { "val" : "FMA:66773" }, { - "val" : "ZFA:0009040" + "val" : "ZFA:0009040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -632,7 +805,13 @@ "val" : "Mesothelial cells are crucial components of the mesothelium, a protective layer that lines the body's internal cavities, including pleural cavity (around the lungs), the pericardial cavity (around the heart), and the peritoneal cavity (within the abdomen). Derived from the embryonic mesoderm layer, these cells exhibit a squamous-like epithelial morphology, usually appearing as a single layer of flat, pavement-like cells in their healthy state.\nMesothelial cells play a vital role in various physiological processes, such as intraperitoneal immunity, fibrinolysis, tissue repair, and tumor suppression. Their primary function is to provide a slippery, non-adhesive and protective surface to reduce friction and eases the movements of the organs within the pleural, pericardial, and peritoneal cavities, and they participate in the transport and movement of fluid and various molecules across the so-called serosal cavities. \nThese cells have adaptive capabilities that facilitate their role in many pathological processes. In response to injury or inflammation, mesothelial cells can undergo morphological and functional changes, such as mesothelial-mesenchymal transitions, aiding in wound healing and tissue repair. Dysfunctions of mesothelial cells, however, can lead to serious health conditions, including adhesions, fibrosis, and malignancies such as peritoneal and pleural mesotheliomas.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000077", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -650,7 +829,13 @@ }, { "val" : "MESH:D001773" }, { - "val" : "ZFA:0009044" + "val" : "ZFA:0009044", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -679,7 +864,13 @@ }, { "val" : "FMA:66772" }, { - "val" : "ZFA:0009065" + "val" : "ZFA:0009065", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -704,7 +895,13 @@ "val" : "neurectoderm cell" } ], "xrefs" : [ { - "val" : "ZFA:0009080" + "val" : "ZFA:0009080", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -776,14 +973,26 @@ }, { "val" : "FMA:70546" }, { - "val" : "ZFA:0009081" + "val" : "ZFA:0009081", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. These cells originate mainly from the mesoderm of the embryo, which forms connective tissues, muscle, and the circulatory and urinary systems. However, in adults, MSCs are found in multiple tissues, including bone marrow, adipose tissue, the umbilical cord, and dental tissues. \nThe primary function of MSCs is to maintain and repair the tissues in which they are found. When damage occurs, the MSCs are able to migrate to the site of injury, where they aid in regenerating the damaged tissue by differentiating into the required cell type and by secreting growth factors that enhance tissue repair and reduce inflammation. Furthermore, MSCs can also act as immunomodulators, suppressing immune reactions and reducing inflammation, both locally and systemically.\nApart from their role in tissue maintenance and repair, MSCs are integral to the field of regenerative medicine and are being investigated for their therapeutic potential in various clinical settings. Owing to their multipotent nature, immunomodulatory activity, and the relative ease of isolation, these cells can be engineered and translated into therapies to treat a variety of diseases, including bone and cartilage defects, liver diseases, heart disorders, and autoimmune diseases, amongst others. They have also been used as vectors for anticancer agents and in cell and gene therapy applications.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000134", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val" : "https://github.com/obophenotype/cell-ontology/issues/474" @@ -858,7 +1067,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -873,15 +1082,30 @@ }, { "val" : "CALOHA:TS-2032" }, { - "val" : "FBbt:00005074" + "val" : "FBbt:00005074", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67328" }, { "val" : "WBbt:0003675" }, { - "val" : "ZFA:0009114" + "val" : "ZFA:0009114", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle cell" }, { @@ -921,7 +1145,13 @@ }, { "val" : "FMA:14072" }, { - "val" : "ZFA:0009118" + "val" : "ZFA:0009118", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -931,7 +1161,13 @@ "val" : "Smooth muscle cells are a specialized type of muscle cells that are primarily found within the walls of hollow organs such as the intestine, stomach, bladder, uterus, and blood vessels. These cells are an essential component of the autonomic nervous system controling involuntary movements within the body.\nSmooth muscle cells play a vital role in many physiological processes due to their unique functionality. They can contract and relax in a slow, sustained, and controlled manner to help modulate the size and shape of the lumens of the organs they surround. For example, in the digestive system, coordinated contraction and relaxation of smooth muscle cells propels food along the gastrointestinal tract - a process known as peristalsis. In the blood vessels, the smooth muscle cells, by contracting or relaxing, either constrict or dilate the vessels, which in turn, help regulate blood flow and pressure.\nOn a cellular level, smooth muscle cells possess a single, centrally located nucleus and contain an arranged network of actin and myosin filaments, which are the proteins responsible for muscle contraction. Unlike their counterparts in skeletal or cardiac muscles, these cells lack specific contact points for these filaments, hence the lack of visible striations. Furthermore, the contraction of smooth muscle cells is regulated by hormones and neurotransmitters, such as acetylcholine and norepinephrine, adding an additional layer of complex regulation to these highly specialized cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000192" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000192", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "smooth muscle cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "smooth muscle cell" @@ -948,7 +1184,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009128" + "val" : "ZFA:0009128", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -971,7 +1213,13 @@ "xrefs" : [ { "val" : "CALOHA:TS-0995" }, { - "val" : "ZFA:0009131" + "val" : "ZFA:0009131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -985,7 +1233,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009136" + "val" : "ZFA:0009136", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1009,7 +1263,13 @@ "xrefs" : [ { "val" : "FMA:72549" }, { - "val" : "ZFA:0009137" + "val" : "ZFA:0009137", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1036,14 +1296,26 @@ "xrefs" : [ { "val" : "FMA:72554" }, { - "val" : "ZFA:0009138" + "val" : "ZFA:0009138", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesodermal cells are pluripotent and the most abundant in the human body. They contribute to the development of several structures such as the skeletal muscles, bones, heart and blood vessels, kidneys, gonads, connective tissues, and certain layers of the skin. Hence, the mesoderm is often regarded as an active and diverse layer due to its role in forming many bodily structures. \nIn embryonic development, these cells are instrumental, contributing to the body's structures through a carefully coordinated sequence of morphogenetic movements. This process forms the complex multicellular architecture of tissues and organs from a simple ball of cells. Without the function of mesodermal cells, the body's integral structures and systems would cease to form correctly, leading to developmental disorders such as axial mesodermal dysplasia complex\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000222", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesodermal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesodermal cell" @@ -1066,7 +1338,13 @@ "xrefs" : [ { "val" : "FMA:72555" }, { - "val" : "ZFA:0009139" + "val" : "ZFA:0009139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1105,7 +1383,13 @@ "val" : "Erythrocytes, also known as red blood cells, are a type of specialized cell that make up the largest percentage of cells in the human body. Erythrocytes are biconcave in shape and lack nuclei and organelles, allowing them to carry oxygen and carbon dioxide through the bloodstream more efficiently. The main function of erythrocytes is to transport oxygen from the lungs to the body's tissues and organs, and to transport carbon dioxide from the body's tissues to the lungs, where it can be exhaled out of the body. Hemoglobin, a protein located inside erythrocytes, is responsible for binding to oxygen. \nErythrocytes are produced in the bone marrow and have a lifespan of approximately 120 days before they are broken down and recycled by the body. Erythrocytes are regulated by the hormone erythropoietin, which is produced by the kidneys and liver in response to low oxygen levels in the body, thereby stimulating erythrocyte production .\nIn addition to their role in oxygen transport, erythrocytes also play a key role in regulating the body's pH levels. Without erythrocytes, oxygen would not be able to be transported efficiently throughout the body and tissues would not receive the necessary oxygen to function properly. Overall, erythrocytes are essential for maintaining the health and homeostasis of the body.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "erythrocyte on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "erythrocyte" @@ -1160,7 +1444,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009164" + "val" : "ZFA:0009164", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1180,7 +1470,13 @@ "xrefs" : [ { "val" : "FMA:86667" }, { - "val" : "ZFA:0007086" + "val" : "ZFA:0007086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1198,7 +1494,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009166" + "val" : "ZFA:0009166", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1257,7 +1559,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009190" + "val" : "ZFA:0009190", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1275,7 +1583,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009193" + "val" : "ZFA:0009193", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1297,7 +1611,13 @@ }, { "val" : "FMA:83624" }, { - "val" : "ZFA:0009226" + "val" : "ZFA:0009226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1307,7 +1627,13 @@ "val" : "Stromal cells constitute a significant portion of the structural cellular milieu (stroma) that supports the function of parenchymal (functional) cells within an organ. The stroma is the connective, supportive framework of biological tissues with various functions depending on the specific organ and cell type. Stromal cells, derived from the mesenchymal lineage, play crucial roles in creating, maintaining, and repairing the tissue microenvironment in virtually all mammalian organs, making these cells indispensable to biological function.\nAdditionally, stromal cells secrete growth factors, cytokines, and extracellular matrix (ECM) molecules to constitute an interactive cellular network and ensure an optimal environment for the functional cells. Beyond mere structural support, these cells are instrumental in wound healing, inflammation, and maintaining tissue integrity. They may also influence the behavior of other cell types through direct cell-cell interactions or paracrine signaling.\nClinically and in research, stromal cells often draw attention due to their interaction with tumors in the cancer microenvironment. Over the past years, the role of stromal cells as facilitators of tumor growth and metastasis has been recognized increasingly. They contribute to cancer progression not only by modulating the ECM but also through the secretion of various bioactive molecules and interacting with immune cells, thereby influencing the immunologic responses to tumors.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "stromal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "stromal cell" @@ -1334,14 +1660,26 @@ "xrefs" : [ { "val" : "FMA:84798" }, { - "val" : "ZFA:0009235" + "val" : "ZFA:0009235", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "A precursor to the smooth muscle cell, the smooth muscle myoblast, is integral to various body systems, including the cardiovascular, gastrointestinal, and respiratory systems. Smooth muscle myoblasts arise from the differentiation of mesenchymal stem cells, a process tightly regulated by specific genetic factors and environmental signals. Their role extends to myogenesis, particularly in the formation of muscular tissue, especially during embryonic development.\nSmooth muscle myoblasts possess distinctive cellular characteristics. In contrast to skeletal muscle myoblasts, they do not fuse to create multinucleated fibers. Instead, they differentiate into individual, uninucleated smooth muscle cells. This differentiation unfolds in two distinct phases: proliferation, marked by rapid division to increase cell numbers, and differentiation, involving structural and functional transformation into mature smooth muscle cells. This intricate process is intricately mediated by various signaling molecules and transcription factors.\nFunctionally, smooth muscle myoblasts and the mature muscle cells they generate play pivotal roles in various physiological processes. Smooth muscle cells orchestrate involuntary muscle responses and are integral to body systems that regulate blood flow, propel food along the digestive tract, and control airflow in the respiratory tract. These diverse functions underscore the significance of smooth muscle myoblasts in the body's growth, maintenance, and overall function.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000514" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000514", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "smooth muscle myoblast on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "smooth muscle myoblast" @@ -1367,7 +1705,13 @@ }, { "val" : "CALOHA:TS-0683" }, { - "val" : "FBbt:00005106" + "val" : "FBbt:00005106", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:54527" }, { @@ -1375,7 +1719,13 @@ }, { "val" : "WBbt:0003679" }, { - "val" : "ZFA:0009248" + "val" : "ZFA:0009248", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1444,7 +1794,13 @@ "xrefs" : [ { "val" : "FMA:83505" }, { - "val" : "ZFA:0005236" + "val" : "ZFA:0005236", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1489,7 +1845,13 @@ "xrefs" : [ { "val" : "FMA:83506" }, { - "val" : "ZFA:0005241" + "val" : "ZFA:0005241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1630,7 +1992,13 @@ "val" : "A megakaryocyte is a large, unique, and complex cell type found primarily in the bone marrow, the spongy, semi-solid tissue located in the medullary cavities of certain bones. The term ‘megakaryocyte’ is derived from the Greek 'mega', meaning great, and 'karyon', referring to the nucleus. Megakaryocytes are characterized by their large size, typically with a diameter of 50-100 µm in humans, and the presence of a multilobulated nucleus; they are the largest hematopoietic cells in the bone marrow but also the rarest cells. \nThe primary function of a megakaryocyte is the production of platelets, also known as thrombocytes. Platelets are small, anucleate cell fragments that play a crucial role in the process of hemostasis, the arrest of blood loss from a damaged blood vessel. The process begins when the megakaryocyte extends long, branching processes called proplatelets, into the sinusoidal blood vessels present in the bone marrow. These proplatelets then fragment into the discoid structures recognized as platelets. Each megakaryocyte can produce thousands of platelets during its lifespan. \nApart from platelet production, megakaryocytes are involved in several other functions. They express immune-sensing receptors such as Fc-γ receptor and Toll-like receptors and produce factors such as platelet factor 4 and platelet-derived growth factor that can stimulate the immune system. Also, in certain pathological conditions, megakaryocytes release TGF-β and PDGF and contribute to bone marrow fibrosis, a condition characterized by excessive accumulation of fibrous tissue in the bone marrow leading to anemia. Recent studies have also highlighted the role of megakaryocytes in regulating hematopoiesis, the process of blood cell production. They can influence the bone marrow microenvironment and control the behavior of hematopoietic stem cells, the progenitors of all types of blood cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "megakaryocyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1650,7 +2018,13 @@ }, { "val" : "MESH:D012156" }, { - "val" : "ZFA:0009252" + "val" : "ZFA:0009252", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1676,7 +2050,13 @@ "val" : "chondroplast" } ], "xrefs" : [ { - "val" : "ZFA:0009258" + "val" : "ZFA:0009258", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1724,7 +2104,13 @@ "xrefs" : [ { "val" : "BTO:0002315" }, { - "val" : "ZFA:0009387" + "val" : "ZFA:0009387", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1754,7 +2140,13 @@ "xrefs" : [ { "val" : "FMA:84138" }, { - "val" : "ZFA:0005238" + "val" : "ZFA:0005238", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1785,14 +2177,26 @@ }, { "val" : "MESH:D050527" }, { - "val" : "ZFA:0009283" + "val" : "ZFA:0009283", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Mesangial cells are specialized cells that primarily reside in the middle layer, or mesangium, of the renal glomerulus within the kidney. The primary function of mesangial cells is to maintain the structural stability and function of the glomerular capillary tuft. They achieve this by providing structural support to the capillary loops, controlling the surface area available for filtration in response to physiological alterations in blood pressure, and removing trapped material and proteins from the basement membrane, which otherwise could cause damage. Moreover, mesangial cells regulate the glomerular blood flow by contracting and relaxing, similar to smooth muscle cells. They also synthesize extracellular matrix components, including collagen and fibronectin, that form the structural framework of the glomerulus.\nBeyond their structural and regulatory roles, mesangial cells are involved in several immunologic functions. They express a variety of receptors that can recognize immune complexes and subsequently mediate an inflammatory reaction. Their role in the immune response includes the production of a variety of cytokines and growth factors, which make them a key cellular component in the progression of several renal diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000650" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000650", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesangial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1810,14 +2214,26 @@ "val" : "window cell" } ], "xrefs" : [ { - "val" : "ZFA:0009286" + "val" : "ZFA:0009286", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Fenestrated cells are specialized epithelial cells that are characterized by a distinctive structural feature, fenestrations or tiny pores, which allow an exchange of substances such as fluids, nutrients, and waste between blood vessels and the surrounding tissue environments. These cells are present in various types of epithelial tissues in the human body, including the intestinal tract, endocrine glands, and certain parts of the renal system. \nThere are multiple types of endothelial cell fenestrations. The most common type is found in systemic capillaries of the endocrine tissue (e.g., pancreatic islets), gastrointestinal mucosa, and renal peritubular capillaries. Here, the fenestrated cells have fenestrations in their peripheral cytoplasm with a unique thin and permeable diaphragm that provides a high degree of selectivity, blocking the passage of larger molecules while allowing the free movement of smaller ones. In contrast, other types of fenestrations, such as the discontinuous epithelium of the liver sinusoidal endothelial cells, do not have diaphragms. \nCharacteristically, fenestrated cells play a vital role in the filtering process of body systems. They are a key part of the glomeruli in the kidneys where blood is filtered under high pressure. The fenestrations present in the endothelial cells lining the capillaries of the glomerulus allow the free passage of water and small solute molecules towards the Bowman's capsule, leaving behind larger proteins and cells in the blood, thereby aiding in the filtration and waste removal process. \nIn the endocrine system, fenestrated cells in glandular capillaries allow the prompt release of hormones into the bloodstream. These cells have tightly clustered fenestrations which increase the surface area available for passive diffusion, improving the efficiency of hormone secretion. In villi of the small intestine, these cells increase absorption efficiency, permitting the exchange of water, electrolytes, and nutrients.\nOverall, fenestrated cells contribute immensely to important physiological processes of filtration, absorption, and secretion, primarily connecting our body's circulation system with the surrounding tissues and organs.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000666" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000666", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "fenestrated endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1856,7 +2272,13 @@ }, { "val" : "FMA:63174" }, { - "val" : "ZFA:0009112" + "val" : "ZFA:0009112", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -1866,7 +2288,13 @@ "val" : "Pericytes, also known as Rouget cells, are a type of cell embedded in the wall of small blood vessels such as capillaries and venules. Not only do these cells share a basement membrane with endothelial cells, but they also have a direct physical contact with them, forming the blood-brain and blood-retinal barrier. They are an essential component of the neurovascular unit, a structure critical for maintaining brain homeostasis and a consistent neural microenvironment.\nPericytes play a crucial role in the regulation of microvascular blood flow and permeability. They dynamically respond to changes in blood flow and can relax or contract like smooth muscle cells, thereby controlling capillary diameter and blood flow to the tissues. Moreover, pericytes contribute significantly to the regulation of endothelial cell proliferation and migration, implying their vital role in angiogenesis and the stability of blood vessels. Their ability to differentiate into multiple cell types, including fibroblasts, macrophages, and smooth muscle cells, reveals their importance in tissue repair and remodeling.\nFurthermore, pericytes have demonstrated functions in regulating immune and inflammatory responses. Pericytes also collaborate with endothelial cells in preserving the integrity of the blood-brain barrier, thus protecting the central nervous system from potential damage due to harmful substances and pathogens.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000669" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000669", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "pericyte on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -1880,14 +2308,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0009291" + "val" : "ZFA:0009291", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Muscle precursor cells, commonly referred to as myogenic progenitor cells or myoblasts, play a pivotal role in the intricate processes of muscle regeneration and development. As undifferentiated cells, they harbor the potential to evolve into distinct specialized cells, specifically the muscle cell or myocyte. Their crucial contribution lies in guiding the transformation of the mesodermal layer, one of the three primary germ cell layers in the early embryo, into fully developed skeletal muscle tissues during embryonic development.\nMuscle precursor cells are characterized by their proliferative capacity and rapid differentiation into mature myocytes. They fuse into myotubes, culminating in the formation of muscle fibers. Their responsiveness to signals such as insulin-like growth factors, transforming growth factor-β, and neural inputs enables precise control over their proliferation and differentiation. This regenerative capacity equips them with the ability to repair injured or damaged muscle tissue, a critical function in preserving muscle homeostasis and overall function. These cells also actively contribute to adaptive responses, such as muscle growth and strengthening, in reaction to factors like training or aging.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000680", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "muscle precursor cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "muscle precursor cell" @@ -1908,14 +2348,26 @@ }, { "val" : "MESH:D053687" }, { - "val" : "ZFA:0009307" + "val" : "ZFA:0009307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Somatic stem cells, also known as adult stem cells, are undifferentiated cells found throughout the body post-embryonic development. They reside in specialized niches within tissues such as the bone marrow, brain, muscles, skin, and liver. Fundamentally, these cells possess the ability to self-renew, maintaining their numbers, and to generate differentiated cells that replace dying cells and repair damaged tissues. \nThe potency of somatic stem cells varies based on their tissue of origin. For instance, hematopoietic stem cells in the bone marrow exhibit multipotency, giving rise to all blood cell types. Conversely, muscle stem cells display unipotency, generating only muscle cells.\nSomatic stem cells respond to environmental signals that regulate their quiescence, activation, and differentiation states. In response to tissue injury, they proliferate and differentiate into specific mature cell types to replace lost or damaged cells. Intricate mechanisms ensure a delicate balance between self-renewal and differentiation, guiding tissue maintenance and repair without risking aberrant cell proliferation leading to tumor formation.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000723", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "somatic stem cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somatic stem cell" @@ -1938,7 +2390,13 @@ }, { "val" : "MESH:D022423" }, { - "val" : "ZFA:0009324" + "val" : "ZFA:0009324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -1967,7 +2425,13 @@ }, { "val" : "FMA:83516" }, { - "val" : "ZFA:0009325" + "val" : "ZFA:0009325", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2000,7 +2464,13 @@ }, { "val" : "MESH:D004900" }, { - "val" : "ZFA:0005237" + "val" : "ZFA:0005237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2030,7 +2500,13 @@ }, { "val" : "CALOHA:TS-0448" }, { - "val" : "ZFA:0009354" + "val" : "ZFA:0009354", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2062,7 +2538,13 @@ }, { "val" : "FMA:70339" }, { - "val" : "ZFA:0009356" + "val" : "ZFA:0009356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2101,7 +2583,13 @@ }, { "val" : "FMA:83598" }, { - "val" : "ZFA:0005830" + "val" : "ZFA:0005830", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2164,7 +2652,13 @@ "xrefs" : [ { "val" : "FMA:69074" }, { - "val" : "ZFA:0009385" + "val" : "ZFA:0009385", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2194,7 +2688,13 @@ "xrefs" : [ { "val" : "FMA:69076" }, { - "val" : "ZFA:0009388" + "val" : "ZFA:0009388", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2240,7 +2740,13 @@ "val" : "2010-08-24T02:06:40Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "endothelial cell of vascular tree on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "endothelial cell of vascular tree" @@ -2277,7 +2783,13 @@ "val" : "2010-08-24T10:15:00Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002144" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "capillary endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2409,10 +2921,22 @@ "val" : "An epithelial cell of the proximal tubule, commonly referred to as a proximal tubular epithelial cell, is a specialized brush border cell found lining the proximal tubule within the functional unit of the kidney, the nephron. These cells play a critical role in the resorption process in the kidney and are responsible for maintaining homeostasis, including blood filtration, electrolyte balance, and acid-base balance. Epithelial cells of the proximal tubule have a cuboidal shape and microvilli that increase surface area, facilitating effective reabsorption.\nThe primary function of epithelial cells of the proximal tubule revolves around their ability to reabsorb approximately 60-70% of the glomerular filtrate, retaining essential substances such as sodium, glucose, amino acids, bicarbonate, and certain ions that are filtered out by the glomerulus. Additionally, these cells are also responsible for the secretion of organic acids, bases, and the hydrolysis of small proteins that are reabsorbed after filtration. \nProximal tubule epithelial cells are highly susceptible to apoptosis, and damage to these cells by exposure to toxins, pathogens, or obstructive conditions may result in acute kidney injury.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002306" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002306", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "epithelial cell of proximal tubule on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://xmlns.com/foaf/0.1/depiction", - "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-renal-corpuscle/v1.2/assets/2d-ftu-kidney-renal-corpuscle.png" + "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-renal-corpuscle/v1.2/assets/2d-ftu-kidney-renal-corpuscle.png", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/licence", + "val" : "http://creativecommons.org/licenses/by/4.0/" + } ] + } } ] } }, { @@ -2458,7 +2982,13 @@ }, { "val" : "MESH:D003239" }, { - "val" : "ZFA:0009392" + "val" : "ZFA:0009392", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2488,7 +3018,13 @@ }, { "val" : "WBbt:0007028" }, { - "val" : "ZFA:0007089" + "val" : "ZFA:0007089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2501,7 +3037,13 @@ "val" : "2010-09-15T03:39:21Z" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002321", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "embryonic cell (metazoa) on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "embryonic cell (metazoa)" @@ -2555,7 +3097,13 @@ "xrefs" : [ { "val" : "KUPO:0001019" }, { - "val" : "ZFA:0009374" + "val" : "ZFA:0009374", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2625,14 +3173,26 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0005322" + "val" : "ZFA:0005322", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/description", "val" : "Renal principal cells are the major cell type in the initial collecting tubule and the cortical and outer medullary collecting ducts, as well as the connecting tubule, in the nephrons of the kidneys.\nA key function of renal principal cells is the regulation of water balance in the body. These cells express aquaporin-2 (AQP2) water channels, which facilitate the reabsorption of water from the fluid within the renal tubule lumen back into the blood. The translocation of AQP2 to the cell membrane is controlled by the hormone vasopressin: In response to high vasopressin levels, AQP2 moves to the cell membrane, allowing water to pass through effectively and be reabsorbed, therefore concentrating the urine. Conversely, in low vasopressin conditions, AQP2 is removed from the membrane, reducing water reabsorption and diluting the urine. \nRenal principal cells are also involved in the regulation of sodium and potassium levels in the body. They have sodium channels (ENaC) in their luminal membranes which permit the reabsorption of sodium ions from the tubule fluid back into the blood, resulting in a net reabsorption of sodium ions into the systemic circulation. This process is controlled, in part, by the hormone aldosterone. Additionally, renal principal cells contain potassium channels that facilitate the secretion of potassium ions into the urine. The activities of these channels, in coordination with other cell types in the nephron, are critical for maintaining electrolyte balance and overall body homeostasis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0005009" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0005009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "renal principal cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2646,7 +3206,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "ZFA:0007084" + "val" : "ZFA:0007084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -2700,7 +3266,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset" ], "xrefs" : [ { - "val" : "FBbt:00005070" + "val" : "FBbt:00005070", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -2728,7 +3300,13 @@ "val" : "Mesenchymal cells are a type of undifferentiated cell that possess the ability to develop into a wide variety of other cells. These cells originate from the mesoderm during embryonic development, which gives rise to tissues such as muscles, the skeletal system, and connective and vascular structures. Mesenchymal cells primarily function as progenitor cells with exceptional renewal capabilities and are characterized by their ability to migrate, aiding in tissue repair and regeneration.\nMesenchymal cells play a critical role in the development and maintenance of various biological systems throughout the body due to their versatility and adaptability. They can differentiate into more specialized cells, including osteoblasts, adipocytes, and chondrocytes, which are essential for bone, fat, and cartilage tissues, respectively. Furthermore, they contribute to the vascular and lymphatic systems through the formation of pericytes and lymphatic endothelial cells, securing the integrity of the circulatory system.\nIn the field of regenerative medicine, mesenchymal cells, particularly mesenchymal stem cells (MSCs), are of great interest due to their unique therapeutic potential. MSCs, for instance, have been implicated in wound healing and tissue repair because of their capacity to modulate the immune response. They can secrete a range of proteins and growth factors that aid in angiogenesis, the formation of new blood vessels, and the stimulation of resident progenitor cells to aid in tissue restoration.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0008019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "mesenchymal cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "mesenchymal cell" @@ -2745,7 +3323,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#added_for_HCA", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#human_subset", "http://purl.obolibrary.org/obo/cl#mouse_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { - "val" : "ZFA:0005944" + "val" : "ZFA:0005944", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -2793,7 +3377,13 @@ "val" : "Neural crest cells are a group of transient and highly migratory cells that originate from the neuroectoderm during the early stages of embryonic development. They are multipotent cells with an exceptional degree of plasticity, capable of differentiating into various somatic cell types and therefore play a fundamental role in the formation of various organs and tissues, making them critical contributors to the developing embryo. \nAfter the initiation of neurulation (the formation of the neural tube) neural crest cells start to undergo epithelial-to-mesenchymal transition and delaminate and migrate from the dorsal neural tube to several regions throughout the embryo. They differentiate into a range of diverse cell types, such as neurons and glial cells of the peripheral nervous system, including sensory and autonomic neurons. They also contribute to the formation of adrenal glands, pigment cells in the skin (melanocytes), cardiac structures, including parts of the heart septum and major arteries, as well as bones and cartilage of the face and skull.\nDisorders or aberrations in the development or migration of the neural crest cells can lead to serious congenital malformations, such as neurocristopathies, including Hirschsprung disease, neuroblastoma, and neurofibromatosis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "neural crest cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "neural crest cell" @@ -2915,7 +3505,13 @@ "val" : "Epithelial cells of the nephron form the epithelial lining of the nephron, the functional unit of the kidney that filters the blood to produce urine. Each kidney holds approximately one million nephrons, each of which is composed of several distinct parts, including the renal corpuscle, the proximal tubule, the loop of Henle, and the distal tubule. All sections are lined with highly specialized epithelial cells adapted to perform different functions within the sections of the nephron. \nThe different epithelial cells of the nephron play crucial roles in the process of filtration, reabsorption, secretion, and excretion, essential tasks for the regulation of body fluid composition and volume. During filtration, the blood is forced through the walls of glomerular capillaries into the Bowman's capsule, where waste products, electrolytes, and water are separated from the blood cells and proteins. As the filtrate then passes through the nephron, epithelial cells of the tubular portion reabsorb useful substances such as glucose, amino acids, and electrolytes, along with most of the water back into the bloodstream. Waste products like urea and creatinine, as well as excess ions and water, remain in the tubule for elimination.\nIn addition, epithelial cells of the nephron also play a vital part in maintaining the body's acid-base balance by actively secreting hydrogen ions into the urine while reabsorbing bicarbonate from the urine back into the blood. They are also involved in the regulation of blood pressure through the renin-angiotensin-aldosterone system and contribute to erythrocyte production by releasing the hormone erythropoietin in response to low oxygen levels in the blood. Abnormalities or damage in renal epithelial cells often result in impaired kidney function, leading to various renal diseases.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000449" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "epithelial cell of nephron on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -2970,7 +3566,13 @@ "val" : "Kidney collecting duct epithelial cells are a specialized type of cells that form an integral part of the renal system. Located in the collecting duct system of the kidneys, these cells are responsible for one of the final steps in the process of urine formation, and they are instrumental in the fine tuning of the volume and composition of urine by reabsorbing water and certain solutes back into the bloodstream.\nThese cells express specific channels and carriers that actively and passively transport ions and water. They also have channels on their membranes, such as sodium channels and potassium channels, involved in reabsorbing or secreting these electrolytes depending upon the body's needs. The function of renal collecting duct epithelial cells can be regulated by a variety of hormones, including vasopressin (antidiuretic hormone), which can modulate the ion channels and carriers and hence indirectly influence body fluid homeostasis.\nAside from their function in ion and water balance, kidney collecting duct epithelial cells also aid in maintaining the body's acid-base balance. They have specialized functionality to secret hydrogen ions into the tubular lumen, which contributes to acid excretion. Any dysfunction may have serious implications and lead to various renal or systemic diseases, exemplifying the importance of these cells in maintaining overall body homeostasis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000454" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000454", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney collecting duct epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3006,7 +3608,13 @@ "xrefs" : [ { "val" : "KUPO:0001010" }, { - "val" : "ZFA:0009389" + "val" : "ZFA:0009389", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3021,7 +3629,13 @@ "xrefs" : [ { "val" : "KUPO:0001013" }, { - "val" : "ZFA:0009390" + "val" : "ZFA:0009390", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3037,7 +3651,13 @@ "xrefs" : [ { "val" : "KUPO:0001017" }, { - "val" : "ZFA:0009391" + "val" : "ZFA:0009391", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } } ] } }, { @@ -3175,7 +3795,13 @@ "val" : "The kidney interstitial fibroblasts are crucial cells found predominantly in the interstitium of the kidneys. These cells play a significant role in maintaining kidney structure and orchestrating key physiological procedures related to kidney function. The interstitium forms a complex network with other cells, capillaries, and the renal tubules, which are crucial for maintaining kidney functions.\nFunctionally, these cells participate in renal homeostasis by synthesizing and secreting vital extracellular matrix (ECM) components, such as collagen, proteoglycan, and fibronectin, which contribute to the structural integrity of the kidneys. Additionally, these fibroblasts provide supportive tissues to nephrons (structural and functional units of kidneys), help in regulating fluid and electrolyte balance, along with providing an arena for immune response in case of any infection or damage. They are also integral to the regulation of kidney blood flow and maintenance of tubular structures by stabilizing capillaries through synthesis of angiogenic factors.\nUnder pathological conditions, such as renal fibrosis, kidney interstitial fibroblasts can transform into myofibroblasts, which speed up the production and deposition of extracellular matrix proteins. This overproduction can lead to scar formation and affect the kidney's functionality, often leading to a chronic and progressive loss of renal function.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000692" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000692", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney interstitial fibroblast on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3213,10 +3839,22 @@ "val" : "Kidney connecting tubule epithelial cells are found in collecting duct system of the kidney, specifically in at the interconnection segment between the nephron and the collecting ducts. The epithelial cells lining the connecting tubule are crucial for the journey of filtrate before it empties into urine-collecting ducts and therefore play a critical role in maintaining the body’s fluid and electrolyte balance.\nOne of the principal functions of connecting tubule epithelial cells involves the selective reabsorption and secretion of various solutes. This reabsorption process includes critical regulatory electrolytes such as sodium ions (Na+), chloride ions (Cl-), and bicarbonate ions (HCO3-), thus playing a role in the regulation of the acid-base homeostasis. Their function also involves the secretion of potassium ions (K+) into the renal tubular fluid.\nThe connecting tubule epithelial cells are primarily intercalated cells, which can be categorized into two types according to their specific functions: type A intercalated cells, which secrete acid, and the type B intercalated cells, which secrete base (bicarbonate) and reabsorb chloride. By regulating the concentrations of these ions, as well as reabsorption of water, connecting tubule epithelial cells contribute substantively to maintaining the body's electrolyte levels, pH balance, and overall homeostasis.\nIn addition to intercalating cells, the collecting duct system also has principal cells, which are characterized by the expression of the water channel AQP2. AQP2-expressing cells have also been identified in connecting tubules, but there is some controversy whether these represent a unique cell type as there are some morphologic differences compared with principal cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000768" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000768", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney connecting tubule epithelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://xmlns.com/foaf/0.1/depiction", - "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-nephron/v1.2/assets/2d-ftu-kidney-nephron.png" + "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-nephron/v1.2/assets/2d-ftu-kidney-nephron.png", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/licence", + "val" : "http://creativecommons.org/licenses/by/4.0/" + } ] + } } ] } }, { @@ -3240,10 +3878,22 @@ "val" : "Kidney distal convoluted tubule epithelial cells, often referred to simply as distal convoluted tubule (DCT) cells, constitute a significant portion of the nephron -- the functional building unit of the kidney involved in filtration and reabsorption of substances from blood. The DCT epithelial cells form lining of the distal convoluted tubule, a segment of the nephron located after the loop of Henle and before the collecting tubule. These cells are characterized by unique morphological features such as small size, low height and fewer microvilli compared to proximal convoluted tubule epithelial cells. \nThese cells perform a host of vital functions contributing to the regulation of extracellular fluid volume and electrolyte balance, blood pressure and pH. While the DCT is less prominent in water and sodium reabsorption compared to the proximal tubule and the loop of Henle, it plays a crucial role in fine-tuning the process. DCT epithelial cells are responsible for the final adjustments of sodium, potassium and calcium reabsorption, thereby affecting overall fluid and electrolyte balance, blood pressure regulation and bone health. The reabsorption process is regulated by hormones including aldosterone and parathyroid hormone.\nThe distal convoluted tubule (DCT) also plays a significant role in acid-base homeostasis by secreting protons (H+) into the tubular fluid and reabsorbing bicarbonate ions (HCO3-), thus regulating the pH of the blood. The ability of DCT cells to adjust urine concentration plays a part in maintaining the body’s pH balance and preventing conditions like acidosis or alkalosis. In summary, kidney distal convoluted tubule epithelial cells perform functions that are crucial to maintaining body's homeostasis.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000849" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000849", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney distal convoluted tubule epithelial cell on CELLxGENE CellGuide" + } ] + } }, { "pred" : "http://xmlns.com/foaf/0.1/depiction", - "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-nephron/v1.2/assets/2d-ftu-kidney-nephron.png" + "val" : "https://cdn.humanatlas.io/digital-objects/2d-ftu/kidney-nephron/v1.2/assets/2d-ftu-kidney-nephron.png", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/licence", + "val" : "http://creativecommons.org/licenses/by/4.0/" + } ] + } } ] } }, { @@ -3291,7 +3941,13 @@ "val" : "Kidney capillary endothelial cells form the innermost lining of the capillaries and microvessels within kidneys, including those lining the glomerular capillaries and the vasa recta. Each cell exhibits a unique array of adhesion molecules, receptors, and secreted mediators which interact with circulating blood cells and solutes. \nOne of the key functions of kidney capillary endothelial cells is enabling filtration, reabsorption, secretion, and excretion – the crucial steps in the formation of urine. In the glomerulus, these cells form a collaborative relationship with the podocytes to constitute the glomerular filtration barrier; here, the ultra-thin endothelial cells create a wall through which water and small solutes pass while retaining larger proteins and molecules within the bloodstream. This permits the rapid and selective filtration of plasma, a primary aspect of the kidney's role in waste clearance and fluid, electrolyte, and acid-base homeostasis.\nKidney capillary endothelial cells also conduct multiple homeostatic roles, such as vasomotor control, fibrinolysis, platelet adhesion, inflammation, and coagulation. They also play a crucial role in responding to renal injury by participating in fibrogenesis, an initial response following acute kidney injury. The endothelial cells spearhead angiogenesis (new blood vessel formation) and the repair and regeneration of renal tissue, thereby enhancing the survival function of the kidney itself. Furthermore, factors secreted by kidney capillary endothelial cells also help control the growth and differentiation of other types of renal cells.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000892" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000892", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney capillary endothelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3354,7 +4010,13 @@ "val" : "The kidney loop of Henle descending limb epithelial cells are highly specialized cells that play a crucial role in maintaining the body's salt and water balance. These cells line the descending limb of the loop of Henle, which is a portion of the renal tubule located in the kidneys, an organ responsible for filtering waste products, ions and extra water from the blood and converting them into urine. However, the descending limb epithelial cells are specifically involved in the countercurrent multiplication system, a mechanism to concentrate urine that involves both active and passive transport processes. \nThese cells are notably permeable to water but relatively impermeable to solutes, a characteristic that dramatically influences the osmotic gradient in the renal medulla. As filtrate initially descends down the loop of Henle, water gets drawn out due to the increasing osmotic gradient, thereby concentrating the filtrate. Additionally, these epithelial cells are exceptionally thin walled, allowing water to freely diffuse across the membrane.\nFurthermore, the kidney loop of Henle descending limb epithelial cells are inextricably linked to the functioning of numerous diuretic drugs, which work by blocking the reabsorption of water and certain electrolytes in the kidneys, leading to increased urine production to rid the body of excess fluids.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" }, { "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://cellxgene.cziscience.com/cellguide/CL_1001021" + "val" : "https://cellxgene.cziscience.com/cellguide/CL_1001021", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "kidney loop of Henle descending limb epithelial cell on CELLxGENE CellGuide" + } ] + } } ] } }, { @@ -3454,7 +4116,13 @@ }, { "val" : "MetaCyc:PEPTIDYLTRANSFERASE-RXN" }, { - "val" : "Reactome:R-HSA-156912" + "val" : "Reactome:R-HSA-156912", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Peptide transfer from P-site tRNA to the A-site tRNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -3462,6 +4130,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25493" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30193" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -3510,7 +4181,13 @@ "val" : "mitosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-69278" + "val" : "Reactome:R-HSA-69278", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle, Mitotic" + } ] + } }, { "val" : "Wikipedia:Mitosis" } ], @@ -3700,7 +4377,13 @@ "xrefs" : [ "GOC:dph", "GOC:sdb_2009", "GOC:tb" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9823730" + "val" : "Reactome:R-HSA-9823730", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Formation of definitive endoderm" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -3791,41 +4474,6 @@ "val" : "biological_process" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/GO_0001977", - "lbl" : "renal system process involved in regulation of blood volume", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.", - "xrefs" : [ "GOC:dph", "GOC:tb", "ISBN:0721643949" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_obsoletion_candidate" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "renal blood volume control of blood pressure" - }, { - "pred" : "hasRelatedSynonym", - "val" : "renal regulation of blood volume", - "xrefs" : [ "GOC:dph", "GOC:tb" ] - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_2" - }, { - "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_2157" - }, { - "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4896" - }, { - "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4932" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "biological_process" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001990", "lbl" : "regulation of systemic arterial blood pressure by hormone", @@ -4336,7 +4984,13 @@ "val" : "water homeostasis by the renal system" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-432040" + "val" : "Reactome:R-HSA-432040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Vasopressin regulates renal water homeostasis via Aquaporins" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -4449,6 +5103,9 @@ "val" : "molecular function" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is the same as GO molecular function" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] @@ -5076,7 +5733,13 @@ "val" : "protein translation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72766" + "val" : "Reactome:R-HSA-72766", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Translation" + } ] + } }, { "val" : "Wikipedia:Translation_(genetics)" } ], @@ -5109,7 +5772,13 @@ "val" : "translation initiation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72613" + "val" : "Reactome:R-HSA-72613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Initiation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5134,7 +5803,13 @@ "val" : "translation elongation" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-156842" + "val" : "Reactome:R-HSA-156842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Elongation" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5161,7 +5836,13 @@ "val" : "translational complex disassembly" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-72764" + "val" : "Reactome:R-HSA-72764", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Eukaryotic Translation Termination" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5215,7 +5896,13 @@ "val" : "single-organism transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382551" + "val" : "Reactome:R-HSA-382551", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of small molecules" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -5243,7 +5930,13 @@ "val" : "ion transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-425393" + "val" : "Reactome:R-HSA-425393", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Transport of inorganic cations/anions and amino acids/oligopeptides" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5260,7 +5953,13 @@ "xrefs" : [ "GOC:ai" ] }, "xrefs" : [ { - "val" : "Reactome:R-HSA-445717" + "val" : "Reactome:R-HSA-445717", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Aquaporin-mediated transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5328,7 +6027,13 @@ "val" : "signaling (initiator) caspase activity" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-109581" + "val" : "Reactome:R-HSA-109581", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptosis" + } ] + } }, { "val" : "Wikipedia:Apoptosis" } ], @@ -5378,7 +6083,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-445355" + "val" : "Reactome:R-HSA-445355", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Smooth Muscle Contraction" + } ] + } }, { "val" : "Wikipedia:Muscle_contraction" } ], @@ -5426,7 +6137,13 @@ "val" : "single-organism organelle organization" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1852241" + "val" : "Reactome:R-HSA-1852241", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Organelle biogenesis and maintenance" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -5454,7 +6171,13 @@ "val" : "cell-division cycle" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1640170" + "val" : "Reactome:R-HSA-1640170", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell Cycle" + } ] + } }, { "val" : "Wikipedia:Cell_cycle" } ], @@ -5528,7 +6251,13 @@ "val" : "signalling pathway" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-212718" + "val" : "Reactome:R-HSA-212718", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "EGFR interacts with phospholipase C-gamma" + } ] + } }, { "val" : "Wikipedia:Signal_transduction" } ], @@ -5578,23 +6307,77 @@ "xrefs" : [ "GOC:dph" ] } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-112316" - }, { - "val" : "Reactome:R-HSA-442720" - }, { - "val" : "Reactome:R-HSA-442729" - }, { - "val" : "Reactome:R-HSA-442742" - }, { - "val" : "Reactome:R-HSA-451307" - }, { - "val" : "Reactome:R-HSA-451308" - }, { - "val" : "Reactome:R-HSA-9619229" - }, { - "val" : "Reactome:R-HSA-9619483" - }, { - "val" : "Reactome:R-HSA-9620244" + "val" : "Reactome:R-HSA-112316", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Neuronal System" + } ] + } + }, { + "val" : "Reactome:R-HSA-442720", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through the activation of Adenylate Cyclase" + } ] + } + }, { + "val" : "Reactome:R-HSA-442729", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde" + } ] + } + }, { + "val" : "Reactome:R-HSA-442742", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" + } ] + } + }, { + "val" : "Reactome:R-HSA-451307", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of Na-permeable kainate receptors" + } ] + } + }, { + "val" : "Reactome:R-HSA-451308", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of Ca-permeable Kainate Receptor" + } ] + } + }, { + "val" : "Reactome:R-HSA-9619229", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of RAC1 downstream of NMDARs" + } ] + } + }, { + "val" : "Reactome:R-HSA-9619483", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Activation of AMPK downstream of NMDARs" + } ] + } + }, { + "val" : "Reactome:R-HSA-9620244", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Long-term potentiation" + } ] + } }, { "val" : "Wikipedia:Neurotransmission" } ], @@ -5672,7 +6455,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9758941" + "val" : "Reactome:R-HSA-9758941", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Gastrulation" + } ] + } }, { "val" : "Wikipedia:Gastrulation" } ], @@ -5710,7 +6499,13 @@ "val" : "pan-neural process" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-9675108" + "val" : "Reactome:R-HSA-9675108", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Nervous system development" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -5774,7 +6569,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8935690" + "val" : "Reactome:R-HSA-8935690", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Digestion" + } ] + } }, { "val" : "Wikipedia:Digestion" } ], @@ -5902,7 +6703,13 @@ "val" : "establishment and maintenance of protein localization" } ], "xrefs" : [ { - 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"val" : "Reactome:R-HSA-5357801" + "val" : "Reactome:R-HSA-5357801", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Programmed Cell Death" + } ] + } }, { "val" : "Wikipedia:Programmed_cell_death" } ], @@ -6666,7 +7491,13 @@ "xrefs" : [ "GOC:ai" ] }, "xrefs" : [ { - "val" : "Reactome:R-HSA-8981607" + "val" : "Reactome:R-HSA-8981607", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Intracellular oxygen transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -6794,7 +7625,13 @@ "val" : "RNA metabolism" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953854" + "val" : "Reactome:R-HSA-8953854", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of RNA" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -6851,17 +7688,42 @@ "xrefs" : [ { "val" : "EC:2.-.-.-" }, { - 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"val" : "Reactome:R-HSA-392499" + "val" : "Reactome:R-HSA-392499", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Metabolism of proteins" + } ] + } }, { "val" : "Wikipedia:Protein_metabolism" } ], @@ -7284,7 +8182,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -7298,6 +8196,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/26279" }, { @@ -7314,6 +8215,7 @@ "val" : "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "PMID:18391171" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "formation of a cell surface projection" @@ -7323,6 +8225,9 @@ "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -7872,6 +8777,9 @@ "val" : "protein-protein complex" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "This is not covalently bonded, which conflicts with changes to the parent definition." + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -7956,7 +8864,13 @@ "val" : "ATP hydrolysis coupled ion transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-983712" + "val" : "Reactome:R-HSA-983712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ion channel transport" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -8153,8 +9067,8 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "Any biological process involved in the maintenance of an internal steady state.", - "xrefs" : [ "GOC:jl", "ISBN:0395825172" ] + "val" : "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions.", + "xrefs" : [ "PMID:26265027" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_mouse" ], "synonyms" : [ { @@ -8177,6 +9091,9 @@ "val" : "regulation of homeostatic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/31175" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8300,7 +9217,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "PMID:16318917" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -8312,6 +9229,9 @@ "val" : "cellular projection" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/23013" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" }, { @@ -9058,7 +9978,13 @@ "val" : "reproductive process in a multicellular organism" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-1474165" + "val" : "Reactome:R-HSA-1474165", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Reproduction" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -9650,7 +10576,13 @@ "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { - "val" : "Reactome:R-HSA-8953897" + "val" : "Reactome:R-HSA-8953897", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cellular responses to stimuli" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", @@ -9676,11 +10608,29 @@ "val" : "ATP hydrolysis coupled transmembrane transport" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-382556" + "val" : "Reactome:R-HSA-382556", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "ABC-family proteins mediated transport" + } ] + } }, { - "val" : "Reactome:R-HSA-425407" + "val" : "Reactome:R-HSA-425407", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "SLC-mediated transmembrane transport" + } ] + } }, { - "val" : "Reactome:R-HSA-5223345" + "val" : "Reactome:R-HSA-5223345", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Miscellaneous transport and binding events" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", @@ -10061,24 +11011,6 @@ "val" : "biological_process" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/GO_0071705", - "lbl" : "nitrogen compound transport", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.", - "xrefs" : [ "GOC:mah" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_obsoletion_candidate" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2010-03-08T03:56:28Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "biological_process" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/GO_0071826", "lbl" : "protein-RNA complex organization", @@ -10259,11 +11191,29 @@ "val" : "induction of apoptosis by extracellular signals" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-193681" + "val" : "Reactome:R-HSA-193681", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Ceramide signalling" + } ] + } }, { - "val" : "Reactome:R-HSA-204998" + "val" : "Reactome:R-HSA-204998", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Cell death signalling via NRAGE, NRIF and NADE" + } ] + } }, { - "val" : "Reactome:R-HSA-75157" + "val" : "Reactome:R-HSA-75157", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "FasL/ CD95L signaling" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -10293,7 +11243,13 @@ "val" : "apoptosis" } ], "xrefs" : [ { - "val" : "Reactome:R-HSA-75153" + "val" : "Reactome:R-HSA-75153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#label", + "val" : "Apoptotic execution phase" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", @@ -10442,7 +11398,7 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098643", - "lbl" : "fibrillar collagen", + "lbl" : "fibrillar collagen complex", "type" : "CLASS", "meta" : { "definition" : { @@ -10452,6 +11408,9 @@ "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "banded collagen fibril" + }, { + "pred" : "hasExactSynonym", + "val" : "fibrillar collagen" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", @@ -10495,14 +11454,21 @@ } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098645", - "lbl" : "collagen network", + "lbl" : "complex of network-forming collagens", "type" : "CLASS", "meta" : { "definition" : { "val" : "A supramolecular complex that consists of collagen triple helices associated to form a network.", "xrefs" : [ "GOC:dos", "PMID:21421911" ] }, + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "collagen network" + } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/30938" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] @@ -10650,8 +11616,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.", - "xrefs" : [ "GOC:kmv" ] + "val" : "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { @@ -10659,6 +11624,12 @@ "val" : "cellular anatomical entity" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", + "val" : "Overlaps with some cellular components from GO" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" }, { @@ -11552,6 +12523,46 @@ "val" : "Eukaryota" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "lbl" : "Choanoflagellata", + "type" : "CLASS", + "meta" : { + "synonyms" : [ { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name", + "pred" : "hasExactSynonym", + "val" : "choanoflagellates" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellatea" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanoflagellida" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanomonada" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#synonym", + "pred" : "hasRelatedSynonym", + "val" : "Choanozoa" + }, { + "synonymType" : "http://purl.obolibrary.org/obo/ncbitaxon#blast_name", + "pred" : "hasRelatedSynonym", + "val" : "choanoflagellates" + } ], + "xrefs" : [ { + "val" : "GC_ID:1" + }, { + "val" : "PMID:27765632" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "ncbi_taxonomy" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "lbl" : "Euarchontoglires", @@ -12589,6 +13600,21 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0001591", + "lbl" : "curvature", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.", + "xrefs" : [ "WordNet:WordNet" ] + }, + "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0001690", "lbl" : "contractile", @@ -12945,6 +13971,32 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0002254", + "lbl" : "flattened", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane.", + "xrefs" : [ "PATOC:CVS" ] + }, + "comments" : [ "Becoming flat but not necessarily completely flat." ], + "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], + "synonyms" : [ { + "pred" : "hasRelatedSynonym", + "val" : "compressed" + } ], + "basicPropertyValues" : [ { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0002-2061-091X" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2010-08-16T03:59:34Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002266", "lbl" : "3-D shape", @@ -14383,11 +15435,23 @@ }, { "val" : "EHDAA2:0003193" }, { - "val" : "EMAPA:37283" + "val" : "EMAPA:37283", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100155" }, { - "val" : "FBbt:00007000" + "val" : "FBbt:00007000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000144" }, { @@ -14399,7 +15463,13 @@ }, { "val" : "NCIT:C61460" }, { - "val" : "UMLS:C0598782" + "val" : "UMLS:C0598782", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Appendage" + } ] + } }, { "val" : "VSAO:0000075" }, { @@ -14449,7 +15519,13 @@ }, { "val" : "TAO:0005425" }, { - "val" : "UMLS:C0036760" + "val" : "UMLS:C0036760", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Serosa" + } ] + } }, { "val" : "Wikipedia:Serous_membrane" }, { @@ -14535,7 +15611,13 @@ }, { "val" : "SCTID:302511008" }, { - "val" : "UMLS:C0041951" + "val" : "UMLS:C0041951", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ureter" + } ] + } }, { "val" : "VHOG:0000605" }, { @@ -14590,7 +15672,13 @@ }, { "val" : "SCTID:302513006" }, { - "val" : "UMLS:C0041967" + "val" : "UMLS:C0041967", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Urethra" + } ] + } }, { "val" : "VHOG:0001264" }, { @@ -14633,7 +15721,13 @@ "xrefs" : [ { "val" : "AAO:0011123" }, { - "val" : "FBbt:00100314" + "val" : "FBbt:00100314", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:30320" }, { @@ -14643,7 +15737,13 @@ }, { "val" : "TAO:0005171" }, { - "val" : "UMLS:C0687028" + "val" : "UMLS:C0687028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Duct" + } ] + } }, { "val" : "Wikipedia:Duct_(anatomy)" }, { @@ -14723,7 +15823,13 @@ }, { "val" : "FAO:0000001" }, { - "val" : "FBbt:00007001" + "val" : "FBbt:00007001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:305751" }, { @@ -14808,7 +15914,13 @@ }, { "val" : "SCTID:272625005" }, { - "val" : "UMLS:C0178784" + "val" : "UMLS:C0178784", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ" + } ] + } }, { "val" : "WBbt:0003760" }, { @@ -14816,7 +15928,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33090" @@ -14936,47 +16054,161 @@ }, { "val" : "BilaDO:0000004" }, { - "val" : "BtauDv:0000078" - }, { - "val" : "CfamDv:0000007" - }, { - "val" : "ChirDv:0000014" - }, { - "val" : "DpseDv:0000005" - }, { - "val" : "DsimDv:0000005" + "val" : "BtauDv:0000078", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000014", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001272" }, { - "val" : "EcabDv:0000007" + "val" : "EcabDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005369" }, { - "val" : "FcatDv:0000007" - }, { - "val" : "GgalDv:0000076" - }, { - "val" : "GgorDv:0000032" - }, { - "val" : "HsapDv:0010000" - }, { - "val" : "MmulDv:0000052" - }, { - "val" : "MmusDv:0000092" - }, { - "val" : "OanaDv:0000007" - }, { - "val" : "OariDv:0000024" - }, { - "val" : "PpanDv:0000041" - }, { - "val" : "PtroDv:0000052" - }, { - "val" : "RnorDv:0000061" - }, { - "val" : "SsalDv:0000040" - }, { - "val" : "SscrDv:0000084" + "val" : "FcatDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000076", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000032", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0010000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000041", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000061", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000040", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000084", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000041" }, { @@ -15007,65 +16239,203 @@ "val" : "embryogenesis" } ], "xrefs" : [ { - 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"val" : "EcabDv:0000002" + "val" : "EcabDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00005289" }, { "val" : "FMA:72652" }, { - "val" : "FcatDv:0000002" - }, { - "val" : "GgalDv:0000002" - }, { - "val" : "GgorDv:0000002" - }, { - "val" : "HsapDv:0000045" - }, { - "val" : "MdomDv:0000002" - }, { - "val" : "MmulDv:0000002" - }, { - "val" : "MmusDv:0000042" + "val" : "FcatDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000045", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000042", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000000" }, { "val" : "OGES:000022" }, { - 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"val" : "SsalDv:0000002" - }, { - "val" : "SscrDv:0000002" + "val" : "SsalDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000003" }, { @@ -15184,7 +16554,13 @@ }, { "val" : "TAO:0001288" }, { - "val" : "UMLS:C0022663" + "val" : "UMLS:C0022663", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Glomerulus" + } ] + } }, { "val" : "Wikipedia:Glomerulus" }, { @@ -15232,7 +16608,13 @@ }, { "val" : "SCTID:118966000" }, { - "val" : "UMLS:C1519343" + "val" : "UMLS:C1519343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System_Part" + } ] + } }, { "val" : "galen:ComplexSkeletalStructure" } ], @@ -15317,7 +16699,13 @@ }, { "val" : "TAO:0000529" }, { - "val" : "UMLS:C0025492" + "val" : "UMLS:C0025492", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesonephros" + } ] + } }, { "val" : "VHOG:0000038" }, { @@ -15382,7 +16770,13 @@ }, { "val" : "SCTID:308797000" }, { - "val" : "UMLS:C0231049" + "val" : "UMLS:C0231049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Metanephros" + } ] + } }, { "val" : "VHOG:0000039" }, { @@ -15486,7 +16880,13 @@ }, { "val" : "SCTID:361528000" }, { - "val" : "UMLS:C1284058" + "val" : "UMLS:C1284058", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Metanephric_Diverticulum" + } ] + } }, { "val" : "VHOG:0000541" }, { @@ -15521,7 +16921,13 @@ }, { "val" : "OGES:000024" }, { - "val" : "SsalDv:0000038" + "val" : "SsalDv:0000038", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000022" }, { @@ -15591,55 +16997,193 @@ "val" : "lifespan" } ], "xrefs" : [ { - 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"val" : "FcatDv:0000001" - }, { - "val" : "GgalDv:0000001" - }, { - "val" : "GgorDv:0000001" - }, { - "val" : "HsapDv:0000001" - }, { - "val" : "MdomDv:0000001" - }, { - "val" : "MmulDv:0000001" - }, { - "val" : "MmusDv:0000001" + "val" : "FcatDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MdomDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000011" }, { - "val" : "OanaDv:0000001" - }, { - "val" : "OariDv:0000001" - }, { - "val" : "OcunDv:0000001" - }, { - "val" : "PpanDv:0000001" - }, { - "val" : "PtroDv:0000001" - }, { - "val" : "RnorDv:0000001" - }, { - "val" : "SsalDv:0000001" - }, { - "val" : "SscrDv:0000001" + "val" : "OanaDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PpanDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "ncithesaurus:Life" } ], @@ -15678,63 +17222,201 @@ "val" : "stage" } ], "xrefs" : [ { - "val" : "AcarDv:0000000" + "val" : "AcarDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "BILS:0000105" }, { - "val" : "BtauDv:0000000" - }, { - "val" : "CfamDv:0000000" - }, { - "val" : "ChirDv:0000000" - }, { - "val" : "CporDv:0000000" - }, { - "val" : "DpseDv:0000000" - }, { - "val" : "DsimDv:0000000" + "val" : "BtauDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CfamDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "ChirDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "CporDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DpseDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "DsimDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0000399" }, { - "val" : "EcabDv:0000000" + "val" : "EcabDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "FBdv:00007012" }, { "val" : "FMA:24120" }, { - "val" : "FcatDv:0000000" - }, { - "val" : "GgalDv:0000000" - }, { - "val" : "GgorDv:0000000" - }, { - "val" : "HsapDv:0000000" + "val" : "FcatDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D008018" }, { - "val" : "MdomDv:0000000" - }, { - "val" : "MmulDv:0000000" - }, { - "val" : "MmusDv:0000000" - }, { - "val" : "OanaDv:0000000" - }, { - "val" : "OariDv:0000000" - }, { - "val" : "OcunDv:0000000" + "val" : "MdomDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmulDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OanaDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OcunDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000090" }, { - "val" : "PpanDv:0000000" - }, { - "val" : "PtroDv:0000000" - }, { - "val" : "RnorDv:0000000" - }, { - "val" : "SsalDv:0000000" - }, { - "val" : "SscrDv:0000000" + "val" : "PpanDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "PtroDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000002" }, { @@ -15805,7 +17487,13 @@ }, { "val" : "BilaDO:0000005" }, { - "val" : "ChirDv:0000003" + "val" : "ChirDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001322" }, { @@ -15813,21 +17501,57 @@ }, { "val" : "FBdv:00005288" }, { - "val" : "HsapDv:0000003" - }, { - "val" : "MmusDv:0000003" + "val" : "HsapDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "NCIT:C12601" }, { - "val" : "OariDv:0000009" + "val" : "OariDv:0000009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000100" }, { - "val" : "RnorDv:0000048" - }, { - "val" : "SsalDv:0000003" - }, { - "val" : "SscrDv:0000087" + "val" : "RnorDv:0000048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000087", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "VHOG:0000745" }, { @@ -15860,33 +17584,81 @@ }, { "val" : "BilaDO:0000006" }, { - "val" : "ChirDv:0000004" + "val" : "ChirDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001290" }, { "val" : "FBdv:00000054" }, { - "val" : "GgalDv:0000064" - }, { - "val" : "HsapDv:0000005" + "val" : "GgalDv:0000064", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "MESH:D002970" }, { - "val" : "MmusDv:0000004" + "val" : "MmusDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000015" }, { "val" : "OGES:000020" }, { - "val" : "OariDv:0000010" + "val" : "OariDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "PdumDv:0000200" }, { - "val" : "RnorDv:0000049" - }, { - "val" : "SsalDv:0000004" - }, { - "val" : "SscrDv:0000088" + "val" : "RnorDv:0000049", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000004", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000088", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Cleavage_(embryo)" }, { @@ -15914,15 +17686,39 @@ }, { "val" : "BilaDO:0000007" }, { - "val" : "ChirDv:0000010" + "val" : "ChirDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001282" }, { - "val" : "GgalDv:0000091" - }, { - "val" : "HsapDv:0000006" - }, { - "val" : "MmusDv:0000007" + "val" : "GgalDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000003" }, { @@ -15930,13 +17726,37 @@ }, { "val" : "OGES:000021" }, { - "val" : "OariDv:0000025" - }, { - "val" : "RnorDv:0000054" - }, { - "val" : "SsalDv:0000012" - }, { - "val" : "SscrDv:0000089" + "val" : "OariDv:0000025", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000089", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000005" }, { @@ -15997,29 +17817,77 @@ }, { "val" : "BilaDO:0000008" }, { - "val" : "ChirDv:0000011" + "val" : "ChirDv:0000011", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "EFO:0001296" }, { "val" : "FBdv:00005317" }, { - "val" : "GgalDv:0000092" - }, { - "val" : "HsapDv:0000010" - }, { - "val" : "MmusDv:0000013" + "val" : "GgalDv:0000092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000004" }, { "val" : "OGES:000019" }, { - "val" : "OariDv:0000026" - }, { - "val" : "RnorDv:0000005" - }, { - "val" : "SsalDv:0000016" - }, { - "val" : "SscrDv:0000090" + "val" : "OariDv:0000026", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000090", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "WBls:0000010" }, { @@ -16046,19 +17914,61 @@ }, { "val" : "BilaDO:0000009" }, { - "val" : "ChirDv:0000012" - }, { - "val" : "GgalDv:0000093" - }, { - "val" : "HsapDv:0000012" - }, { - "val" : "MmusDv:0000017" - }, { - "val" : "OariDv:0000027" - }, { - "val" : "RnorDv:0000007" - }, { - "val" : "SscrDv:0000091" + "val" : "ChirDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000012", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "OariDv:0000027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000007", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "XAO:1000006" } ], @@ -16091,25 +18001,73 @@ }, { "val" : "BilaDO:0000010" }, { - "val" : "ChirDv:0000013" - }, { - "val" : "GgalDv:0000094" - }, { - "val" : "HsapDv:0000015" - }, { - "val" : "MmusDv:0000018" + "val" : "ChirDv:0000013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "GgalDv:0000094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "HsapDv:0000015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "MmusDv:0000018", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "OGES:000005" }, { "val" : "OGES:000032" }, { - "val" : "OariDv:0000028" - }, { - "val" : "RnorDv:0000055" - }, { - "val" : "SsalDv:0000022" - }, { - "val" : "SscrDv:0000086" + "val" : "OariDv:0000028", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "RnorDv:0000055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SsalDv:0000022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } + }, { + "val" : "SscrDv:0000086", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/UnspecifiedMatching" + } ] + } }, { "val" : "Wikipedia:Organogenesis" } ], @@ -16261,7 +18219,13 @@ }, { "val" : "SCTID:370631000" }, { - "val" : "UMLS:C0008987" + "val" : "UMLS:C0008987", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cloaca" + } ] + } }, { "val" : "VHOG:0001186" }, { @@ -16348,7 +18312,13 @@ }, { "val" : "SCTID:50961009" }, { - "val" : "UMLS:C0231057" + "val" : "UMLS:C0231057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Urogenital_Sinus" + } ] + } }, { "val" : "VHOG:0000414" }, { @@ -16443,7 +18413,13 @@ }, { "val" : "EMAPA:16262" }, { - "val" : "FBbt:00003126" + "val" : "FBbt:00003126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:49184" }, { @@ -16602,7 +18578,13 @@ }, { "val" : "TAO:0000007" }, { - "val" : "UMLS:C0005767" + "val" : "UMLS:C0005767", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood" + } ] + } }, { "val" : "VHOG:0000224" }, { @@ -16739,7 +18721,13 @@ }, { "val" : "NCIT:C74601" }, { - "val" : "UMLS:C0933845" + "val" : "UMLS:C0933845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Parenchyma" + } ] + } }, { "val" : "Wikipedia:Parenchyma" } ], @@ -16824,7 +18812,13 @@ }, { "val" : "SCTID:30737000" }, { - "val" : "UMLS:C0022664" + "val" : "UMLS:C0022664", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Medulla" + } ] + } }, { "val" : "Wikipedia:Renal_medulla" }, { @@ -16941,7 +18935,13 @@ "xrefs" : [ { "val" : "BTO:0001837" }, { - "val" : "EMAPA:37950" + "val" : "EMAPA:37950", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:62889" }, { @@ -17010,7 +19010,13 @@ }, { "val" : "NCIT:C34062" }, { - "val" : "UMLS:C1516992" + "val" : "UMLS:C1516992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland_Fluid_or_Secretion" + } ] + } }, { "val" : "galen:Secretion" } ], @@ -17065,7 +19071,13 @@ }, { "val" : "EMAPA:35178" }, { - "val" : "FBbt:00007019" + "val" : "FBbt:00007019", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9669" }, { @@ -17139,7 +19151,13 @@ }, { "val" : "EHDAA2:0003005" }, { - "val" : "FBbt:00007017" + "val" : "FBbt:00007017", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:5897" }, { @@ -17151,7 +19169,13 @@ }, { "val" : "TGMA:0001825" }, { - "val" : "UMLS:C0524461" + "val" : "UMLS:C0524461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lumen_Space" + } ] + } }, { "val" : "VHOG:0001728" }, { @@ -17194,7 +19218,13 @@ }, { "val" : "EHDAA2:0003006" }, { - "val" : "FBbt:00007016" + "val" : "FBbt:00007016", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67165" }, { @@ -17246,7 +19276,13 @@ }, { "val" : "EHDAA2:0003007" }, { - "val" : "FBbt:00007015" + "val" : "FBbt:00007015", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67112" }, { @@ -17326,7 +19362,13 @@ }, { "val" : "EV:0100000" }, { - "val" : "FBbt:00004856" + "val" : "FBbt:00004856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7149" }, { @@ -17342,7 +19384,13 @@ }, { "val" : "TGMA:0001831" }, { - "val" : "UMLS:C0460002" + "val" : "UMLS:C0460002", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Organ_System" + } ] + } }, { "val" : "VHOG:0001725" }, { @@ -17440,7 +19488,13 @@ }, { "val" : "EV:0100016" }, { - "val" : "FBbt:00000001" + "val" : "FBbt:00000001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:256135" }, { @@ -17574,7 +19628,13 @@ }, { "val" : "EMAPA:36031" }, { - "val" : "FBbt:00007009" + "val" : "FBbt:00007009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7153" }, { @@ -17594,7 +19654,13 @@ }, { "val" : "TGMA:0001840" }, { - "val" : "UMLS:C0229962" + "val" : "UMLS:C0229962", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Body_Part" + } ] + } }, { "val" : "VHOG:0001758" }, { @@ -17650,7 +19716,13 @@ }, { "val" : "EHDAA2:0003040" }, { - "val" : "FBbt:00007013" + "val" : "FBbt:00007013", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:63863" }, { @@ -17689,7 +19761,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007277" + "val" : "FBbt:00007277", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "VHOG:0001737" } ], @@ -17748,7 +19826,13 @@ }, { "val" : "EMAPA:35868" }, { - "val" : "FBbt:00007003" + "val" : "FBbt:00007003", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9637" }, { @@ -17764,7 +19848,13 @@ }, { "val" : "TGMA:0001844" }, { - "val" : "UMLS:C0040300" + "val" : "UMLS:C0040300", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Tissue" + } ] + } }, { "val" : "VHOG:0001757" }, { @@ -17820,7 +19910,13 @@ }, { "val" : "EHDAA2:0003055" }, { - "val" : "FBbt:00007010" + "val" : "FBbt:00007010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "HAO:0000055" }, { @@ -17886,7 +19982,13 @@ }, { "val" : "EMAPA:32738" }, { - "val" : "FBbt:00007005" + "val" : "FBbt:00007005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:9639" }, { @@ -17904,7 +20006,13 @@ }, { "val" : "TAO:0001486" }, { - "val" : "UMLS:C0014609" + "val" : "UMLS:C0014609", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Epithelium" + } ] + } }, { "val" : "VHOG:0000387" }, { @@ -17963,7 +20071,13 @@ }, { "val" : "EHDAA2_RETIRED:0003068" }, { - "val" : "FBbt:00007027" + "val" : "FBbt:00007027", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45567" }, { @@ -17975,7 +20089,13 @@ }, { "val" : "TAO:0001496" }, { - "val" : "UMLS:C0836135" + "val" : "UMLS:C0836135", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Columnar_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_columnar_epithelium" }, { @@ -18032,7 +20152,13 @@ }, { "val" : "TAO:0001494" }, { - "val" : "UMLS:C0682575" + "val" : "UMLS:C0682575", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stratified_Epithelium" + } ] + } }, { "val" : "Wikipedia:Stratified_epithelium" }, { @@ -18085,7 +20211,13 @@ }, { "val" : "TAO:0001498" }, { - "val" : "UMLS:C0836133" + "val" : "UMLS:C0836133", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Simple_squamous_epithelium" }, { @@ -18194,7 +20326,13 @@ }, { "val" : "TAO:0001495" }, { - "val" : "UMLS:C0682574" + "val" : "UMLS:C0682574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Simple_Epithelium" + } ] + } }, { "val" : "XAO:0004007" }, { @@ -18359,7 +20497,13 @@ }, { "val" : "EMAPA:16039" }, { - "val" : "FBbt:00000052" + "val" : "FBbt:00000052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69068" }, { @@ -18377,7 +20521,13 @@ }, { "val" : "SCTID:57991002" }, { - "val" : "UMLS:C0013935" + "val" : "UMLS:C0013935", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryo" + } ] + } }, { "val" : "VHOG:0001766" }, { @@ -18439,7 +20589,13 @@ }, { "val" : "EMAPA:36033" }, { - "val" : "FBbt:00000110" + "val" : "FBbt:00000110", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69069" }, { @@ -18453,9 +20609,21 @@ }, { "val" : "TAO:0001122" }, { - "val" : "UMLS:C0920502" - }, { - "val" : "UMLS:C1708239" + "val" : "UMLS:C0920502", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Tissue" + } ] + } + }, { + "val" : "UMLS:C1708239", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Germinal_Layer" + } ] + } }, { "val" : "VHOG:0001223" }, { @@ -18502,7 +20670,13 @@ }, { "val" : "EV:0100003" }, { - "val" : "FBbt:00000111" + "val" : "FBbt:00000111", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69070" }, { @@ -18522,7 +20696,13 @@ }, { "val" : "TAO:0000016" }, { - "val" : "UMLS:C0013574" + "val" : "UMLS:C0013574", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ectoderm" + } ] + } }, { "val" : "VHOG:0000153" }, { @@ -18573,7 +20753,13 @@ }, { "val" : "EV:0100005" }, { - "val" : "FBbt:00000125" + "val" : "FBbt:00000125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69071" }, { @@ -18591,7 +20777,13 @@ }, { "val" : "TAO:0000017" }, { - "val" : "UMLS:C0014144" + "val" : "UMLS:C0014144", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endoderm" + } ] + } }, { "val" : "VHOG:0000154" }, { @@ -18657,7 +20849,13 @@ }, { "val" : "EV:0100006" }, { - "val" : "FBbt:00000126" + "val" : "FBbt:00000126", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69072" }, { @@ -18675,7 +20873,13 @@ }, { "val" : "TAO:0000041" }, { - "val" : "UMLS:C0025485" + "val" : "UMLS:C0025485", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesoderm" + } ] + } }, { "val" : "VHOG:0000152" }, { @@ -18745,7 +20949,13 @@ }, { "val" : "EMAPA:16263" }, { - "val" : "FBbt:00000439" + "val" : "FBbt:00000439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:295846" }, { @@ -18755,7 +20965,13 @@ }, { "val" : "TGMA:0000135" }, { - "val" : "UMLS:C1514977" + "val" : "UMLS:C1514977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stomodeum" + } ] + } }, { "val" : "Wikipedia:Stomodeum" }, { @@ -18810,13 +21026,25 @@ }, { "val" : "EMAPA:25038" }, { - "val" : "FBbt:00000123" + "val" : "FBbt:00000123", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "NCIT:C34278" }, { "val" : "TAO:0000066" }, { - "val" : "UMLS:C0231054" + "val" : "UMLS:C0231054", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Proctodeum" + } ] + } }, { "val" : "VHOG:0000139" }, { @@ -18913,7 +21141,13 @@ }, { "val" : "TAO:0000114" }, { - "val" : "UMLS:C0018787" + "val" : "UMLS:C0018787", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Heart" + } ] + } }, { "val" : "VHOG:0000276" }, { @@ -19053,7 +21287,13 @@ }, { "val" : "TAO:0000367" }, { - "val" : "UMLS:C0022417" + "val" : "UMLS:C0022417", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint" + } ] + } }, { "val" : "VHOG:0001276" }, { @@ -19136,7 +21376,13 @@ }, { "val" : "EV:0100100" }, { - "val" : "FBbt:00004857" + "val" : "FBbt:00004857", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7160" }, { @@ -19148,7 +21394,13 @@ }, { "val" : "MA:0000326" }, { - "val" : "MESH:D005835" + "val" : "MESH:D005835", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000305" }, { @@ -19158,7 +21410,13 @@ }, { "val" : "TAO:0000632" }, { - "val" : "UMLS:C1261210" + "val" : "UMLS:C1261210", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Reproductive_System" + } ] + } }, { "val" : "VHOG:0000182" }, { @@ -19233,7 +21491,13 @@ }, { "val" : "TAO:0000413" }, { - "val" : "UMLS:C0018067" + "val" : "UMLS:C0018067", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gonad" + } ] + } }, { "val" : "VHOG:0000397" }, { @@ -19284,7 +21548,13 @@ }, { "val" : "EFO:0000793" }, { - "val" : "FBbt:00005055" + "val" : "FBbt:00005055", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7152" }, { @@ -19381,7 +21651,13 @@ }, { "val" : "EV:0100095" }, { - "val" : "FBbt:00005056" + "val" : "FBbt:00005056", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7159" }, { @@ -19403,7 +21679,13 @@ }, { "val" : "TAO:0000163" }, { - "val" : "UMLS:C1508753" + "val" : "UMLS:C1508753", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Urinary_System" + } ] + } }, { "val" : "VHOG:0000723" }, { @@ -19419,10 +21701,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_110815", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -19452,7 +21746,13 @@ }, { "val" : "CALOHA:TS-2103" }, { - "val" : "MESH:D002319" + "val" : "MESH:D002319", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "VHOG:0001248" }, { @@ -19460,7 +21760,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6073" @@ -19532,7 +21838,13 @@ }, { "val" : "TAO:0000548" }, { - "val" : "UMLS:C0026845" + "val" : "UMLS:C0026845", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle" + } ] + } }, { "val" : "VSAO:0005038" }, { @@ -19595,7 +21907,13 @@ }, { "val" : "EV:0100162" }, { - "val" : "FBbt:00005093" + "val" : "FBbt:00005093", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7157" }, { @@ -19615,7 +21933,13 @@ }, { "val" : "TAO:0000396" }, { - "val" : "UMLS:C0027763" + "val" : "UMLS:C0027763", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nervous_System" + } ] + } }, { "val" : "VHOG:0000402" }, { @@ -19699,7 +22023,13 @@ }, { "val" : "EV:0100163" }, { - "val" : "FBbt:00005094" + "val" : "FBbt:00005094", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:55675" }, { @@ -19717,7 +22047,16 @@ }, { "val" : "TAO:0000012" }, { - "val" : "UMLS:C0927232" + "val" : "UMLS:C0927232", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "BIRNLEX:1099" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Central_Nervous_System" + } ] + } }, { "val" : "VHOG:0000293" }, { @@ -19731,7 +22070,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -19774,7 +22119,13 @@ }, { "val" : "EMAPA:16548" }, { - "val" : "FBbt:00005379" + "val" : "FBbt:00005379", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45616" }, { @@ -19786,7 +22137,13 @@ }, { "val" : "TGMA:0001014" }, { - "val" : "UMLS:C0231051" + "val" : "UMLS:C0231051", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Foregut" + } ] + } }, { "val" : "VHOG:0000285" }, { @@ -19834,7 +22191,13 @@ }, { "val" : "EMAPA:16255" }, { - "val" : "FBbt:00005383" + "val" : "FBbt:00005383", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45617" }, { @@ -19846,7 +22209,13 @@ }, { "val" : "TGMA:0001036" }, { - "val" : "UMLS:C0231052" + "val" : "UMLS:C0231052", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Midgut" + } ] + } }, { "val" : "VHOG:0000290" }, { @@ -19894,7 +22263,13 @@ }, { "val" : "EMAPA:16715" }, { - "val" : "FBbt:00005384" + "val" : "FBbt:00005384", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45618" }, { @@ -19906,7 +22281,13 @@ }, { "val" : "TGMA:0001020" }, { - "val" : "UMLS:C0231053" + "val" : "UMLS:C0231053", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hindgut" + } ] + } }, { "val" : "VHOG:0000459" }, { @@ -19963,7 +22344,13 @@ }, { "val" : "EHDAA2:0003171" }, { - "val" : "FBbt:00005495" + "val" : "FBbt:00005495", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:86589" }, { @@ -19971,7 +22358,13 @@ }, { "val" : "NCIT:C34275" }, { - "val" : "UMLS:C0678727" + "val" : "UMLS:C0678727", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium" + } ] + } }, { "val" : "Wikipedia:Primordium" }, { @@ -20035,7 +22428,13 @@ }, { "val" : "TAO:0001135" }, { - "val" : "UMLS:C0231024" + "val" : "UMLS:C0231024", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Tube" + } ] + } }, { "val" : "VHOG:0000307" }, { @@ -20080,7 +22479,13 @@ }, { "val" : "EHDAA2:0002229" }, { - "val" : "FBbt:10000000" + "val" : "FBbt:10000000", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:62955" }, { @@ -20094,7 +22499,13 @@ }, { "val" : "TGMA:0001822" }, { - "val" : "UMLS:C1515976" + "val" : "UMLS:C1515976", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Structure_System_or_Substance" + } ] + } }, { "val" : "WBbt:0000100" }, { @@ -20168,7 +22579,13 @@ }, { "val" : "SCTID:181369003" }, { - "val" : "UMLS:C0042458" + "val" : "UMLS:C0042458", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Inferior_Vena_Cava" + } ] + } }, { "val" : "VHOG:0001194" }, { @@ -20224,7 +22641,13 @@ }, { "val" : "NCIT:C13283" }, { - "val" : "UMLS:C0042036" + "val" : "UMLS:C0042036", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Urine" + } ] + } }, { "val" : "Wikipedia:Urine" }, { @@ -20265,7 +22688,13 @@ }, { "val" : "TAO:0005154" }, { - "val" : "UMLS:C0039097" + "val" : "UMLS:C0039097", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Synovial_Fluid" + } ] + } }, { "val" : "Wikipedia:Synovial_fluid" }, { @@ -20319,7 +22748,13 @@ }, { "val" : "SCTID:361918002" }, { - "val" : "UMLS:C0086610" + "val" : "UMLS:C0086610", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesothelium" + } ] + } }, { "val" : "Wikipedia:Mesothelium" } ], @@ -20379,7 +22814,13 @@ }, { "val" : "SCTID:116358006" }, { - "val" : "UMLS:C0035092" + "val" : "UMLS:C0035092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Vein" + } ] + } }, { "val" : "Wikipedia:Renal_vein" }, { @@ -20443,7 +22884,13 @@ }, { "val" : "SCTID:362221007" }, { - "val" : "UMLS:C0227666" + "val" : "UMLS:C0227666", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Pelvis" + } ] + } }, { "val" : "Wikipedia:Renal_pelvis" }, { @@ -20498,7 +22945,13 @@ }, { "val" : "SCTID:362211004" }, { - "val" : "UMLS:C0022655" + "val" : "UMLS:C0022655", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Cortex" + } ] + } }, { "val" : "Wikipedia:Renal_cortex" }, { @@ -20583,7 +23036,13 @@ }, { "val" : "TAO:0005281" }, { - "val" : "UMLS:C0227635" + "val" : "UMLS:C0227635", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Corpuscle" + } ] + } }, { "val" : "VHOG:0001262" }, { @@ -20678,7 +23137,13 @@ }, { "val" : "TAO:0005310" }, { - "val" : "UMLS:C0524448" + "val" : "UMLS:C0524448", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bowman_s_Capsule" + } ] + } }, { "val" : "Wikipedia:Bowman%27s_capsule" }, { @@ -20741,7 +23206,13 @@ }, { "val" : "TAO:0001287" }, { - "val" : "UMLS:C0022674" + "val" : "UMLS:C0022674", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Tubule" + } ] + } }, { "val" : "Wikipedia:Renal_tubule" }, { @@ -20864,7 +23335,13 @@ }, { "val" : "EV:0100082" }, { - "val" : "FBbt:00047153" + "val" : "FBbt:00047153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:15711" }, { @@ -20880,7 +23357,13 @@ }, { "val" : "TGMA:0001279" }, { - "val" : "UMLS:C0003461" + "val" : "UMLS:C0003461", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anus" + } ] + } }, { "val" : "WBbt:0005364" }, { @@ -20963,7 +23446,13 @@ }, { "val" : "SCTID:302512001" }, { - "val" : "UMLS:C0005682" + "val" : "UMLS:C0005682", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Bladder" + } ] + } }, { "val" : "VHOG:0000740" }, { @@ -21006,7 +23495,13 @@ "val" : "pelvic girdle" } ], "xrefs" : [ { - "val" : "EMAPA:37862" + "val" : "EMAPA:37862", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:16581" }, { @@ -21014,7 +23509,13 @@ }, { "val" : "SCTID:360010001" }, { - "val" : "UMLS:C0684083" + "val" : "UMLS:C0684083", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pelvic_Girdle" + } ] + } }, { "val" : "VSAO:0000304" } ] @@ -21069,7 +23570,13 @@ }, { "val" : "TAO:0002153" }, { - "val" : "UMLS:C0027713" + "val" : "UMLS:C0027713", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nephron" + } ] + } }, { "val" : "Wikipedia:Nephron" }, { @@ -21146,7 +23653,13 @@ }, { "val" : "TAO:0005290" }, { - "val" : "UMLS:C1514580" + "val" : "UMLS:C1514580", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Proximal_Convoluted_Tube" + } ] + } }, { "val" : "Wikipedia:Proximal_convoluted_tubule" }, { @@ -21198,7 +23711,13 @@ }, { "val" : "SCTID:361335009" }, { - "val" : "UMLS:C0023986" + "val" : "UMLS:C0023986", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Loop_of_Henle" + } ] + } }, { "val" : "VHOG:0001270" }, { @@ -21246,7 +23765,13 @@ }, { "val" : "SCTID:245350001" }, { - "val" : "UMLS:C0227657" + "val" : "UMLS:C0227657", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Descending_Limb_of_the_Henle_s_Loop" + } ] + } }, { "val" : "Wikipedia:Descending_limb_of_loop_of_henle" } ], @@ -21361,7 +23886,13 @@ }, { "val" : "SCTID:361336005" }, { - "val" : "UMLS:C0022676" + "val" : "UMLS:C0022676", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Distal_Convoluted_Tubule" + } ] + } }, { "val" : "Wikipedia:Distal_convoluted_tubule" } ], @@ -21463,7 +23994,13 @@ }, { "val" : "SCTID:362680001" }, { - "val" : "UMLS:C0230120" + "val" : "UMLS:C0230120", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anal_Region" + } ] + } }, { "val" : "VHOG:0000395" }, { @@ -21523,7 +24060,13 @@ }, { "val" : "TAO:0000434" }, { - "val" : "UMLS:C0037253" + "val" : "UMLS:C0037253", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Skeletal_System" + } ] + } }, { "val" : "VHOG:0001254" }, { @@ -21575,7 +24118,13 @@ "xrefs" : [ "Wikipedia:Articular_capsule" ] } ], "xrefs" : [ { - "val" : "EMAPA:37621" + "val" : "EMAPA:37621", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:34836" }, { @@ -21591,7 +24140,13 @@ }, { "val" : "SCTID:182238002" }, { - "val" : "UMLS:C0206207" + "val" : "UMLS:C0206207", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Joint_Capsule" + } ] + } }, { "val" : "Wikipedia:Articular_capsule" }, { @@ -21692,13 +24247,25 @@ }, { "val" : "EMAPA:16247" }, { - "val" : "FBbt:00003125" + "val" : "FBbt:00003125", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:45615" }, { "val" : "MA:0000917" }, { - "val" : "MESH:D041981" + "val" : "MESH:D041981", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "NCIT:C34082" }, { @@ -21706,7 +24273,13 @@ }, { "val" : "TGMA:0001819" }, { - "val" : "UMLS:C0017189" + "val" : "UMLS:C0017189", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrointestinal_Tract" + } ] + } }, { "val" : "VHOG:0000309" }, { @@ -21718,10 +24291,22 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_41324", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "DOI:10.1371/journal.pone.0016309" + } ] + } }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -21770,7 +24355,13 @@ "xrefs" : [ "ZFA:0005145" ] } ], "xrefs" : [ { - "val" : "EMAPA:37474" + "val" : "EMAPA:37474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "EV:0100146" }, { @@ -21860,7 +24451,13 @@ }, { "val" : "TAO:0000005" }, { - "val" : "UMLS:C0003842" + "val" : "UMLS:C0003842", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Artery" + } ] + } }, { "val" : "VHOG:0001251" }, { @@ -21949,7 +24546,13 @@ }, { "val" : "TAO:0000082" }, { - "val" : "UMLS:C0042449" + "val" : "UMLS:C0042449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vein" + } ] + } }, { "val" : "VHOG:0001743" }, { @@ -22044,7 +24647,13 @@ }, { "val" : "NCIT:C49215" }, { - "val" : "UMLS:C0006904" + "val" : "UMLS:C0006904", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary_Endothelium" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -22099,7 +24708,13 @@ }, { "val" : "NCIT:C13356" }, { - "val" : "UMLS:C0032105" + "val" : "UMLS:C0032105", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Plasma" + } ] + } }, { "val" : "Wikipedia:Blood_plasma" } ], @@ -22141,7 +24756,13 @@ }, { "val" : "TAO:0005315" }, { - "val" : "UMLS:C0042520" + "val" : "UMLS:C0042520", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venule" + } ] + } }, { "val" : "VHOG:0001765" }, { @@ -22195,7 +24816,13 @@ }, { "val" : "TAO:0002138" }, { - "val" : "UMLS:C0003847" + "val" : "UMLS:C0003847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Arteriole" + } ] + } }, { "val" : "VHOG:0001763" }, { @@ -22278,7 +24905,13 @@ }, { "val" : "TAO:0002137" }, { - "val" : "UMLS:C0005847" + "val" : "UMLS:C0005847", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel" + } ] + } }, { "val" : "VHOG:0001250" }, { @@ -22344,7 +24977,13 @@ }, { "val" : "TAO:0005250" }, { - "val" : "UMLS:C0935624" + "val" : "UMLS:C0935624", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Capillary" + } ] + } }, { "val" : "VHOG:0001253" }, { @@ -22399,7 +25038,13 @@ }, { "val" : "SCTID:27168002" }, { - "val" : "UMLS:C0014257" + "val" : "UMLS:C0014257", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Endothelium" + } ] + } }, { "val" : "galen:Endothelium" } ], @@ -22491,7 +25136,13 @@ }, { "val" : "EFO:0000461" }, { - "val" : "FBbt:00004208" + "val" : "FBbt:00004208", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:69067" }, { @@ -22507,7 +25158,13 @@ }, { "val" : "TAO:0001105" }, { - "val" : "UMLS:C0013948" + "val" : "UMLS:C0013948", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Embryonic_Structure" + } ] + } }, { "val" : "VSAO:0000178" }, { @@ -22571,7 +25228,13 @@ }, { "val" : "SCTID:118760003" }, { - "val" : "UMLS:C0042779" + "val" : "UMLS:C0042779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Viscera" + } ] + } }, { "val" : "Wikipedia:Viscus" }, { @@ -22632,7 +25295,13 @@ }, { "val" : "SCTID:244383003" }, { - "val" : "UMLS:C0225844" + "val" : "UMLS:C0225844", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Right_Atrium" + } ] + } }, { "val" : "VHOG:0000328" }, { @@ -22725,7 +25394,13 @@ }, { "val" : "TAO:0000471" }, { - "val" : "UMLS:C0018792" + "val" : "UMLS:C0018792", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiac_Atrium" + } ] + } }, { "val" : "VHOG:0000175" }, { @@ -22768,7 +25443,13 @@ }, { "val" : "EHDAA:5049" }, { - "val" : "EMAPA:37721" + "val" : "EMAPA:37721", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71221" }, { @@ -22776,7 +25457,13 @@ }, { "val" : "MAT:0000148" }, { - "val" : "MESH:D013131" + "val" : "MESH:D013131", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/LexicalMatching" + } ] + } }, { "val" : "MIAA:0000148" }, { @@ -22844,7 +25531,13 @@ }, { "val" : "SCTID:322050006" }, { - "val" : "UMLS:C0222646" + "val" : "UMLS:C0222646", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Appendicular_Skeleton" + } ] + } }, { "val" : "VSAO:0000076" }, { @@ -22918,7 +25611,13 @@ }, { "val" : "TAO:0001115" }, { - "val" : "UMLS:C0460005" + "val" : "UMLS:C0460005", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trunk" + } ] + } }, { "val" : "Wikipedia:Torso" }, { @@ -22966,7 +25665,13 @@ }, { "val" : "MIAA:0000119" }, { - "val" : "UMLS:C0022646" + "val" : "UMLS:C0022646", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Kidney" + } ] + } }, { "val" : "Wikipedia:Kidney" }, { @@ -23038,7 +25743,13 @@ }, { "val" : "TAO:0000151" }, { - "val" : "UMLS:C0231048" + "val" : "UMLS:C0231048", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pronephros" + } ] + } }, { "val" : "VHOG:0000037" }, { @@ -23169,7 +25880,13 @@ }, { "val" : "SCTID:278858007" }, { - "val" : "UMLS:C0026860" + "val" : "UMLS:C0026860", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Musculoskeletal_System" + } ] + } }, { "val" : "VHOG:0001275" }, { @@ -23295,7 +26012,13 @@ }, { "val" : "SCTID:243949006" }, { - "val" : "UMLS:C0230139" + "val" : "UMLS:C0230139", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Thoracic_Cavity" + } ] + } }, { "val" : "Wikipedia:Thoracic_cavity" } ], @@ -23346,7 +26069,13 @@ }, { "val" : "SCTID:362219002" }, { - "val" : "UMLS:C0022445" + "val" : "UMLS:C0022445", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Juxtaglomerular_Apparatus" + } ] + } }, { "val" : "Wikipedia:Juxtaglomerular_apparatus" } ], @@ -23368,7 +26097,13 @@ "xrefs" : [ { "val" : "BTO:0002494" }, { - "val" : "EMAPA:36561" + "val" : "EMAPA:36561", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:84139" }, { @@ -23376,7 +26111,13 @@ }, { "val" : "NCIT:C33101" }, { - "val" : "UMLS:C0017655" + "val" : "UMLS:C0017655", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesangium" + } ] + } }, { "val" : "Wikipedia:Mesangium" } ], @@ -23461,7 +26202,13 @@ }, { "val" : "EHDAA2:0000267" }, { - "val" : "FBbt:00005060" + "val" : "FBbt:00005060", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:85006" }, { @@ -23473,7 +26220,13 @@ }, { "val" : "TAO:0001438" }, { - "val" : "UMLS:C0333343" + "val" : "UMLS:C0333343", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cavity" + } ] + } }, { "val" : "galen:BodyCavity" } ], @@ -23537,7 +26290,13 @@ }, { "val" : "TAO:0000135" }, { - "val" : "UMLS:C0028439" + "val" : "UMLS:C0028439", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochord" + } ] + } }, { "val" : "VHOG:0000199" }, { @@ -23633,7 +26392,13 @@ }, { "val" : "TAO:0000155" }, { - "val" : "UMLS:C0376449" + "val" : "UMLS:C0376449", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somite" + } ] + } }, { "val" : "VHOG:0000191" }, { @@ -23645,7 +26410,13 @@ } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_7712", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "PMID:17237766" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "somite" @@ -23682,7 +26453,13 @@ }, { "val" : "NCIT:C12957" }, { - "val" : "UMLS:C1516995" + "val" : "UMLS:C1516995", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_System" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" }, { @@ -23719,7 +26496,13 @@ }, { "val" : "SCTID:244657003" }, { - "val" : "UMLS:C0227662" + "val" : "UMLS:C0227662", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Macula_Densa" + } ] + } }, { "val" : "Wikipedia:Macula_densa" } ], @@ -23779,7 +26562,13 @@ }, { "val" : "SCTID:361462002" }, { - "val" : "UMLS:C0027789" + "val" : "UMLS:C0027789", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Crest" + } ] + } }, { "val" : "VHOG:0000057" }, { @@ -23851,7 +26640,13 @@ }, { "val" : "EV:0100004" }, { - "val" : "FBbt:00001057" + "val" : "FBbt:00001057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:87657" }, { @@ -23863,7 +26658,13 @@ }, { "val" : "TAO:0001120" }, { - "val" : "UMLS:C1518271" + "val" : "UMLS:C1518271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neuroectoderm" + } ] + } }, { "val" : "VHOG:0000150" }, { @@ -23930,7 +26731,13 @@ }, { "val" : "SCTID:229765004" }, { - "val" : "UMLS:C0030797" + "val" : "UMLS:C0030797", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pelvis" + } ] + } }, { "val" : "Wikipedia:Pelvis" }, { @@ -23980,7 +26787,13 @@ }, { "val" : "SCTID:115976003" }, { - "val" : "UMLS:C0015282" + "val" : "UMLS:C0015282", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Exocrine_Gland" + } ] + } }, { "val" : "Wikipedia:Exocrine_gland" } ], @@ -24043,7 +26856,13 @@ }, { "val" : "TAO:0001641" }, { - "val" : "UMLS:C0009780" + "val" : "UMLS:C0009780", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Connective_Tissue" + } ] + } }, { "val" : "VSAO:0000017" }, { @@ -24111,7 +26930,13 @@ }, { "val" : "SCTID:91727004" }, { - "val" : "UMLS:C2328219" + "val" : "UMLS:C2328219", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Muscle_Tissue" + } ] + } }, { "val" : "Wikipedia:Muscle_tissue" }, { @@ -24189,7 +27014,13 @@ }, { "val" : "TAO:0005023" }, { - "val" : "UMLS:C0018957" + "val" : "UMLS:C0018957", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Hematopoietic_System" + } ] + } }, { "val" : "VHOG:0001624" }, { @@ -24288,7 +27119,13 @@ }, { "val" : "EMAPA:18425" }, { - "val" : "FBbt:00100317" + "val" : "FBbt:00100317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:7146" }, { @@ -24306,7 +27143,13 @@ }, { "val" : "SCTID:134358001" }, { - "val" : "UMLS:C1285092" + "val" : "UMLS:C1285092", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gland" + } ] + } }, { "val" : "Wikipedia:Gland" }, { @@ -24394,7 +27237,13 @@ "xrefs" : [ { "val" : "BIRNLEX:1011" }, { - "val" : "EMAPA:37442" + "val" : "EMAPA:37442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:67552" }, { @@ -24501,7 +27350,13 @@ }, { "val" : "TAO:0000150" }, { - "val" : "UMLS:C1283945" + "val" : "UMLS:C1283945", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pronephric_Duct" + } ] + } }, { "val" : "Wikipedia:Pronephric_duct" }, { @@ -24556,7 +27411,13 @@ }, { "val" : "TE:E5.11.2.0.0.0.4" }, { - "val" : "UMLS:C1511224" + "val" : "UMLS:C1511224", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Island" + } ] + } }, { "val" : "VHOG:0000085" }, { @@ -24617,7 +27478,13 @@ }, { "val" : "TAO:0001206" }, { - "val" : "UMLS:C1284010" + "val" : "UMLS:C1284010", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intermediate_Mesoderm" + } ] + } }, { "val" : "VHOG:0000087" }, { @@ -24721,7 +27588,13 @@ }, { "val" : "TAO:0000546" }, { - "val" : "UMLS:C0043204" + "val" : "UMLS:C0043204", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesonephric_Duct" + } ] + } }, { "val" : "Wikipedia:Mesonephric_duct" }, { @@ -24785,7 +27658,13 @@ }, { "val" : "TAO:0000132" }, { - "val" : "UMLS:C0920623" + "val" : "UMLS:C0920623", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Plate" + } ] + } }, { "val" : "VHOG:0000068" }, { @@ -24846,7 +27725,13 @@ }, { "val" : "TAO:0000255" }, { - "val" : "UMLS:C1284009" + "val" : "UMLS:C1284009", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Paraxial_Mesoderm" + } ] + } }, { "val" : "VHOG:0000114" }, { @@ -24913,7 +27798,13 @@ }, { "val" : "TAO:0000121" }, { - "val" : "UMLS:C1517749" + "val" : "UMLS:C1517749", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Lateral_Mesoderm" + } ] + } }, { "val" : "VHOG:0000118" }, { @@ -24958,7 +27849,13 @@ }, { "val" : "TAO:0000028" }, { - "val" : "UMLS:C1514450" + "val" : "UMLS:C1514450", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordium_of_the_Heart" + } ] + } }, { "val" : "XAO:0000336" }, { @@ -25008,7 +27905,13 @@ }, { "val" : "TAO:0001080" }, { - "val" : "UMLS:C0183176" + "val" : "UMLS:C0183176", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Sclerotome" + } ] + } }, { "val" : "VHOG:0000680" }, { @@ -25115,7 +28018,13 @@ }, { "val" : "TAO:0000393" }, { - "val" : "UMLS:C0162415" + "val" : "UMLS:C0162415", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Mesenchyme" + } ] + } }, { "val" : "VHOG:0000170" }, { @@ -25161,7 +28070,13 @@ "val" : "genitalia" } ], "xrefs" : [ { - "val" : "EMAPA:37731" + "val" : "EMAPA:37731", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0001752" }, { @@ -25173,7 +28088,13 @@ }, { "val" : "TGMA:0000591" }, { - "val" : "UMLS:C0017420" + "val" : "UMLS:C0017420", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Genitalia" + } ] + } }, { "val" : "WBbt:0008422" } ], @@ -25275,7 +28196,13 @@ "xrefs" : [ "OBOL:automatic" ] } ], "xrefs" : [ { - "val" : "EMAPA:37242" + "val" : "EMAPA:37242", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0001903" } ], @@ -25350,7 +28277,13 @@ "xrefs" : [ "OBOL:automatic" ] } ], "xrefs" : [ { - "val" : "EMAPA:37237" + "val" : "EMAPA:37237", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000511" } ], @@ -25437,7 +28370,13 @@ "xrefs" : [ "OBOL:automatic" ] } ], "xrefs" : [ { - "val" : "EMAPA:37240" + "val" : "EMAPA:37240", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000554" } ], @@ -25533,7 +28472,13 @@ "xrefs" : [ "OBOL:automatic" ] } ], "xrefs" : [ { - "val" : "EMAPA:37057" + "val" : "EMAPA:37057", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000524" } ], @@ -25586,7 +28531,13 @@ }, { "val" : "NCIT:C34195" }, { - "val" : "UMLS:C1512940" + "val" : "UMLS:C1512940", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Intraembryonic_Coelom" + } ] + } }, { "val" : "VHOG:0000316" }, { @@ -25619,7 +28570,13 @@ }, { "val" : "NCIT:C67387" }, { - "val" : "UMLS:C0927195" + "val" : "UMLS:C0927195", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Stroma_Connective_Tissue" + } ] + } } ] } }, { @@ -25640,7 +28597,13 @@ }, { "val" : "EHDAA2:0003114" }, { - "val" : "FBbt:00007474" + "val" : "FBbt:00007474", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -25739,7 +28702,13 @@ }, { "val" : "SCTID:244405007" }, { - "val" : "UMLS:C0042460" + "val" : "UMLS:C0042460", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vena_Cava" + } ] + } }, { "val" : "Wikipedia:Venae_cavae" } ], @@ -25954,7 +28923,13 @@ }, { "val" : "SCTID:278861008" }, { - "val" : "UMLS:C0042066" + "val" : "UMLS:C0042066", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Genitourinary_System" + } ] + } }, { "val" : "VHOG:0000286" }, { @@ -26442,9 +29417,21 @@ }, { "val" : "SCTID:361328001" }, { - "val" : "UMLS:C0227629" - }, { - "val" : "UMLS:C1514613" + "val" : "UMLS:C0227629", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Pyramid" + } ] + } + }, { + "val" : "UMLS:C1514613", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Pyramid_of_Malpighi" + } ] + } }, { "val" : "Wikipedia:Renal_pyramids" } ], @@ -26634,7 +29621,13 @@ }, { "val" : "TAO:0005284" }, { - "val" : "UMLS:C0226356" + "val" : "UMLS:C0226356", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Glomerular_Capillary" + } ] + } }, { "val" : "ZFA:0005284" } ], @@ -26758,7 +29751,13 @@ }, { "val" : "SCTID:361438007" }, { - "val" : "UMLS:C0033153" + "val" : "UMLS:C0033153", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primitive_Streak" + } ] + } }, { "val" : "VHOG:0001202" }, { @@ -26823,7 +29822,13 @@ }, { "val" : "TAO:0000010" }, { - "val" : "UMLS:C0007226" + "val" : "UMLS:C0007226", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cardiovascular_System" + } ] + } }, { "val" : "VHOG:0000302" }, { @@ -26949,7 +29954,13 @@ }, { "val" : "SCTID:362060003" }, { - "val" : "UMLS:C1267406" + "val" : "UMLS:C1267406", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Venous_System" + } ] + } }, { "val" : "VHOG:0000277" } ], @@ -26981,7 +29992,13 @@ }, { "val" : "TAO:0005257" }, { - "val" : "UMLS:C1706972" + "val" : "UMLS:C1706972", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Blood_Vessel_Endothelium" + } ] + } }, { "val" : "ZFA:0005257" } ], @@ -27081,7 +30098,13 @@ }, { "val" : "NCIT:C34131" }, { - "val" : "UMLS:C1516779" + "val" : "UMLS:C1516779", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Conceptus" + } ] + } }, { "val" : "Wikipedia:Conceptus" } ], @@ -27145,7 +30168,13 @@ }, { "val" : "SCTID:76147008" }, { - "val" : "UMLS:C1512856" + "val" : "UMLS:C1512856", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Interlobular_Artery" + } ] + } }, { "val" : "Wikipedia:Interlobular_arteries" } ], @@ -27209,7 +30238,13 @@ }, { "val" : "BTO:0001403" }, { - "val" : "FBbt:00005317" + "val" : "FBbt:00005317", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:293108" }, { @@ -27223,9 +30258,21 @@ }, { "val" : "NCIT:C34058" }, { - "val" : "UMLS:C0017199" - }, { - "val" : "UMLS:C1284022" + "val" : "UMLS:C0017199", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Gastrula" + } ] + } + }, { + "val" : "UMLS:C1284022", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Trilaminar_Embryonic_Disc" + } ] + } }, { "val" : "Wikipedia:Gastrula" }, { @@ -27329,7 +30376,13 @@ }, { "val" : "NCIT:C49276" }, { - "val" : "UMLS:C1709902" + "val" : "UMLS:C1709902", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Renal_Tubule_Epithelium" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -27409,7 +30462,13 @@ }, { "val" : "TAO:0002171" }, { - "val" : "UMLS:C0014261" + "val" : "UMLS:C0014261", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_Endothelium" + } ] + } }, { "val" : "VHOG:0001217" }, { @@ -27483,7 +30542,13 @@ }, { "val" : "NCIT:C34301" }, { - "val" : "UMLS:C1519423" + "val" : "UMLS:C1519423", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Somatopleure" + } ] + } }, { "val" : "VHOG:0000557" }, { @@ -27520,7 +30585,13 @@ }, { "val" : "SCTID:361405003" }, { - "val" : "UMLS:C1283944" + "val" : "UMLS:C1283944", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Nephrogenic_Cord" + } ] + } }, { "val" : "Wikipedia:Nephrogenic_cord" } ] @@ -27614,7 +30685,13 @@ "val" : "joint" } ], "xrefs" : [ { - "val" : "FBbt:00005811" + "val" : "FBbt:00005811", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -27651,7 +30728,13 @@ "xrefs" : [ "FMA:71131" ] } ], "xrefs" : [ { - "val" : "FBbt:00100315" + "val" : "FBbt:00100315", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:71131" } ], @@ -27704,7 +30787,13 @@ }, { "val" : "SCTID:361463007" }, { - "val" : "UMLS:C0814992" + "val" : "UMLS:C0814992", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Groove" + } ] + } }, { "val" : "Wikipedia:Neural_groove" }, { @@ -27741,7 +30830,13 @@ }, { "val" : "SCTID:361461009" }, { - "val" : "UMLS:C0814993" + "val" : "UMLS:C0814993", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Neural_Fold" + } ] + } }, { "val" : "Wikipedia:Neural_fold" }, { @@ -28042,7 +31137,13 @@ }, { "val" : "SCTID:245434005" }, { - "val" : "UMLS:C0227658" + "val" : "UMLS:C0227658", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Ascending_Limb_of_the_Henle_s_Loop" + } ] + } }, { "val" : "Wikipedia:Ascending_limb_of_loop_of_Henle" } ], @@ -28158,7 +31259,13 @@ "xrefs" : [ "MA:0000529" ] } ], "xrefs" : [ { - "val" : "EMAPA:37062" + "val" : "EMAPA:37062", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000529" } ], @@ -28183,7 +31290,13 @@ "xrefs" : [ "MA:0000516" ] } ], "xrefs" : [ { - "val" : "EMAPA:37270" + "val" : "EMAPA:37270", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000516" } ], @@ -28208,7 +31321,13 @@ "xrefs" : [ "MA:0000557" ] } ], "xrefs" : [ { - "val" : "EMAPA:37273" + "val" : "EMAPA:37273", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000557" } ], @@ -28239,7 +31358,13 @@ "val" : "pelvis region organ" } ], "xrefs" : [ { - "val" : "EMAPA:37275" + "val" : "EMAPA:37275", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000543" } ] @@ -28260,7 +31385,13 @@ "xrefs" : [ "MA:0000563" ] } ], "xrefs" : [ { - "val" : "EMAPA:37271" + "val" : "EMAPA:37271", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0000563" } ], @@ -28434,7 +31565,13 @@ }, { "val" : "EHDAA2:0003125" }, { - "val" : "FBbt:00007006" + "val" : "FBbt:00007006", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:292313" }, { @@ -28713,13 +31850,25 @@ }, { "val" : "SCTID:68989006" }, { - "val" : "UMLS:C0004799" + "val" : "UMLS:C0004799", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Basement_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_80999", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "http://palaeos.com/metazoa/porifera/homoscleromorpha.html" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "basement membrane of epithelium" @@ -28763,7 +31912,13 @@ }, { "val" : "TAO:0005285" }, { - "val" : "UMLS:C0599297" + "val" : "UMLS:C0599297", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Glomerular_Basement_Membrane" + } ] + } }, { "val" : "Wikipedia:Glomerular_basement_membrane" }, { @@ -28855,7 +32010,13 @@ }, { "val" : "SCTID:361725000" }, { - "val" : "UMLS:C0222645" + "val" : "UMLS:C0222645", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Axial_Skeleton" + } ] + } }, { "val" : "VSAO:0000056" }, { @@ -28914,7 +32075,13 @@ }, { "val" : "SCTID:308826008" }, { - "val" : "UMLS:C0231056" + "val" : "UMLS:C0231056", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Cloacal_Membrane" + } ] + } }, { "val" : "VHOG:0001198" }, { @@ -28944,7 +32111,13 @@ }, { "val" : "NCIT:C34231" }, { - "val" : "UMLS:C1518429" + "val" : "UMLS:C1518429", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Plate" + } ] + } }, { "val" : "VHOG:0001212" } ], @@ -28985,7 +32158,13 @@ }, { "val" : "NCIT:C34232" }, { - "val" : "UMLS:C1518430" + "val" : "UMLS:C1518430", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Notochordal_Process" + } ] + } }, { "val" : "VHOG:0001213" } ], @@ -29015,7 +32194,13 @@ "xrefs" : [ { "val" : "BIRNLEX:20" }, { - "val" : "EMAPA:37441" + "val" : "EMAPA:37441", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:280556" }, { @@ -29059,7 +32244,13 @@ }, { "val" : "SCTID:361333002" }, { - "val" : "UMLS:C1707510" + "val" : "UMLS:C1707510", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Convoluted_Tubule" + } ] + } }, { "val" : "Wikipedia:Convoluted_tubule" } ] @@ -29310,7 +32501,13 @@ "val" : "terminal section of digestive tract" } ], "xrefs" : [ { - "val" : "FBbt:00005756" + "val" : "FBbt:00005756", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "WBbt:0005773" } ], @@ -29362,7 +32559,13 @@ }, { "val" : "SCTID:40118003" }, { - "val" : "UMLS:C0221909" + "val" : "UMLS:C0221909", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Squamous_Epithelium" + } ] + } }, { "val" : "Wikipedia:Squamous_epithelium" } ], @@ -29415,7 +32618,13 @@ }, { "val" : "NCIT:C34022" }, { - "val" : "UMLS:C1515977" + "val" : "UMLS:C1515977", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Anatomic_Surface" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -29534,7 +32743,13 @@ }, { "val" : "SCTID:360394002" }, { - "val" : "UMLS:C1514442" + "val" : "UMLS:C1514442", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Primordial_Gut" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", @@ -29973,7 +33188,13 @@ }, { "val" : "EHDAA2:0003170" }, { - "val" : "FBbt:00005426" + "val" : "FBbt:00005426", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "Wikipedia:Anlage_(biology)" } ], @@ -30060,7 +33281,13 @@ }, { "val" : "NCIT:C33854" }, { - "val" : "UMLS:C0489903" + "val" : "UMLS:C0489903", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Vascular_System" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -30106,7 +33333,13 @@ "val" : "limb girdle region" } ], "xrefs" : [ { - "val" : "EMAPA:37854" + "val" : "EMAPA:37854", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:24874" }, { @@ -30250,7 +33483,13 @@ "val" : "straight tubule" } ], "xrefs" : [ { - "val" : "EMAPA:37489" + "val" : "EMAPA:37489", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002634" }, { @@ -30496,7 +33735,13 @@ "xrefs" : [ "FMA:71637" ] } ], "xrefs" : [ { - "val" : "EMAPA:37091" + "val" : "EMAPA:37091", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:71637" }, { @@ -30574,7 +33819,13 @@ }, { "val" : "NCIT:C32894" }, { - "val" : "UMLS:C0736382" + "val" : "UMLS:C0736382", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Kidney_Lower_Lobe" + } ] + } }, { "val" : "Wikipedia:Renal_lobe" } ], @@ -30604,7 +33855,13 @@ "xrefs" : [ { "val" : "CARO:0010000" }, { - "val" : "FBbt:00100313" + "val" : "FBbt:00100313", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -30826,7 +34083,13 @@ "xrefs" : [ "FMA:7182" ] } ], "xrefs" : [ { - "val" : "EMAPA:37858" + "val" : "EMAPA:37858", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:7182" }, { @@ -30884,7 +34147,13 @@ "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] } ], "xrefs" : [ { - "val" : "EMAPA:37863" + "val" : "EMAPA:37863", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "FMA:7184" }, { @@ -31055,7 +34324,13 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { - "val" : "FBbt:00007330" + "val" : "FBbt:00007330", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } }, { "val" : "FMA:67509" }, { @@ -31143,7 +34418,13 @@ "val" : "main body segment" } ], "xrefs" : [ { - "val" : "FBbt:00057001" + "val" : "FBbt:00057001", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", @@ -31198,7 +34479,13 @@ }, { "val" : "NCIT:C32450" }, { - "val" : "UMLS:C1511770" + "val" : "UMLS:C1511770", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "ncithesaurus:Dense_Connective_Tissue" + } ] + } }, { "val" : "Wikipedia:Dense_connective_tissue" } ], @@ -31289,7 +34576,13 @@ "val" : "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "Wikipedia:Acoelomorpha" + } ] + } }, { "pred" : "http://www.w3.org/2004/02/skos/core#prefLabel", "val" : "coelom" @@ -31730,7 +35023,13 @@ "xrefs" : [ "MA:0002449" ] } ], "xrefs" : [ { - "val" : "EMAPA:37597" + "val" : "EMAPA:37597", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#source", + "val" : "MA:th" + } ] + } }, { "val" : "MA:0002449" } ], @@ -31928,7 +35227,13 @@ "xrefs" : [ { "val" : "CARO:0020000" }, { - "val" : "FBbt:00007276" + "val" : "FBbt:00007276", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "https://w3id.org/sssom/mapping_justification", + "val" : "https://w3id.org/semapv/vocab/ManualMappingCuration" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", @@ -32193,7 +35498,13 @@ "comments" : [ "It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however, most visceral muscles in arthropods are actually striated." ], "synonyms" : [ { "pred" : "hasExactSynonym", - "val" : "visceral muscle" + "val" : "visceral muscle", + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "BTO:0002780" + } ] + } } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", @@ -33842,7 +37153,13 @@ "meta" : { "definition" : { "val" : "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -33858,7 +37175,13 @@ "meta" : { "definition" : { "val" : "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.", - "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ] + "xrefs" : [ "https://orcid.org/0000-0002-6601-2165", "GOC:dph", "GOC:kva", "GOC:pt" ], + "meta" : { + "basicPropertyValues" : [ { + "pred" : "http://www.w3.org/2000/01/rdf-schema#comment", + "val" : "PMID:27812932" + } ] + } }, "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ], "basicPropertyValues" : [ { @@ -34265,7 +37588,7 @@ } }, { "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym", - "lbl" : "has_narrow_synonym", + "lbl" : "has narrow synonym", "type" : "PROPERTY", "propertyType" : "ANNOTATION", "meta" : { @@ -34384,22 +37707,18 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000007", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0002321" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0011115" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000034", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", - "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000034", "pred" : "http://purl.obolibrary.org/obo/RO_0002215", "obj" : "http://purl.obolibrary.org/obo/GO_0017145" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000037", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000037", "pred" : "is_a", @@ -34590,6 +37909,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000076", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000066" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000076", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000077", "pred" : "is_a", @@ -34822,6 +38145,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000219" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000333", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000333", "pred" : "is_a", @@ -35316,6 +38643,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000669", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0008034" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000680", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000680", "pred" : "is_a", @@ -35766,6 +39097,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0002653", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/CL_0000115" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0002653", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0002254" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0002681", "pred" : "is_a", @@ -35786,6 +39121,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0007004", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0007004", "pred" : "is_a", @@ -35846,10 +39185,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000002" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0011026", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/CL_0000255" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0011026", "pred" : "is_a", @@ -36420,14 +39755,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0001841", "pred" : "http://purl.obolibrary.org/obo/RO_0002297", "obj" : "http://purl.obolibrary.org/obo/UBERON_0001049" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0001977", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0003071" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0001977", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", - "obj" : "http://purl.obolibrary.org/obo/GO_0050878" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0001990", "pred" : "is_a", @@ -36560,10 +39887,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0003091", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/GO_0050891" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0003093", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0001977" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0003093", "pred" : "is_a", @@ -36626,7 +39949,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0032991" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005581", - "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "pred" : "http://purl.obolibrary.org/obo/RO_0002160", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0005587", @@ -37028,6 +40351,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008104", "pred" : "http://purl.obolibrary.org/obo/RO_0004009", "obj" : "http://purl.obolibrary.org/obo/PR_000000001" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0008150", + "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", + "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -37199,15 +40526,15 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0015031", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0008104" + "obj" : "http://purl.obolibrary.org/obo/GO_0006810" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0015031", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0045184" + "obj" : "http://purl.obolibrary.org/obo/GO_0008104" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0015031", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0071705" + "obj" : "http://purl.obolibrary.org/obo/GO_0045184" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0015669", "pred" : "is_a", @@ -38292,14 +41619,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0071692", "pred" : "http://purl.obolibrary.org/obo/RO_0004009", "obj" : "http://purl.obolibrary.org/obo/PR_000000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0071705", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/BFO_0000003" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0071705", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0006810" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0071826", "pred" : "is_a", @@ -38744,6 +42063,10 @@ "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_2759", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_131567" + }, { + "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_28009", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33154" }, { "sub" : "http://purl.obolibrary.org/obo/NCBITaxon_314146", "pred" : "is_a", @@ -38940,6 +42263,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0001579", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0001591", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0000052" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0001690", "pred" : "is_a", @@ -39024,6 +42351,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002198", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0001018" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0002254", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001591" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002266", "pred" : "is_a", @@ -46828,6 +50159,13 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0001981" } ] + }, { + "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000076", + "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], + "restrictions" : [ { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002254" + } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000081", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -49659,6 +52997,13 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" } ] + }, { + "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", + "allValuesFromEdges" : [ { + "sub" : "http://purl.obolibrary.org/obo/GO_0005581", + "pred" : "http://purl.obolibrary.org/obo/RO_0002162", + "obj" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" + } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062", "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], diff --git a/subsets/kidney_upper_slim.obo b/subsets/kidney_upper_slim.obo index 8ecd0630b..b7225a1f3 100644 --- a/subsets/kidney_upper_slim.obo +++ b/subsets/kidney_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2025-12-17/subsets/kidney_upper_slim.owl +data-version: cl/releases/2026-03-17/subsets/kidney_upper_slim.owl idspace: dc http://purl.org/dc/elements/1.1/ idspace: foaf http://xmlns.com/foaf/0.1/ idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# @@ -7,7 +7,7 @@ idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: terms http://purl.org/dc/terms/ ontology: cl/subsets/kidney_upper_slim -property_value: owl:versionInfo "2025-12-17" xsd:string +property_value: owl:versionInfo "2026-03-17" xsd:string [Term] id: BFO:0000002 @@ -78,21 +78,18 @@ property_value: skos:prefLabel "early embryonic cell (metazoa)" xsd:string id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] -comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas subset: human_subset subset: mouse_subset -synonym: "animal stem cell" EXACT [] +synonym: "animal stem cell" NARROW [] xref: CALOHA:TS-2086 xref: FMA:63368 xref: ZFA:0005957 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa relationship: RO:0002215 GO:0017145 ! capable of stem cell division property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000034" xsd:string {name="stem cell on CELLxGENE CellGuide"} @@ -119,6 +116,7 @@ xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 xref: ZFA:0009014 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell @@ -396,13 +394,18 @@ property_value: skos:prefLabel "columnar/cuboidal epithelial cell" xsd:string [Term] id: CL:0000076 name: squamous epithelial cell +def: "An epithelial cell that has a flattened morphology." [] subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: CALOHA:TS-1249 xref: ZFA:0009039 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell +intersection_of: CL:0000066 ! epithelial cell +intersection_of: RO:0000053 PATO:0002254 ! has characteristic flattened +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: skos:prefLabel "squamous epithelial cell" xsd:string +property_value: terms:date "2025-12-16T15:56:39Z" xsd:dateTime [Term] id: CL:0000077 @@ -554,6 +557,7 @@ name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset subset: general_cell_types_upper_slim +subset: human_reference_atlas subset: human_subset subset: mouse_subset synonym: "muscle fiber" EXACT [] @@ -571,6 +575,7 @@ is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell relationship: RO:0002202 CL:0000056 ! develops from myoblast property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI +property_value: RO:0002175 NCBITaxon:9606 property_value: skos:prefLabel "muscle cell" xsd:string [Term] @@ -759,6 +764,7 @@ subset: mouse_subset xref: FMA:86667 xref: ZFA:0007086 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell @@ -1271,6 +1277,7 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset xref: ZFA:0009291 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell @@ -1799,6 +1806,7 @@ def: "A squamous shaped endothelial cell." [GOC:dos] subset: human_subset subset: mouse_subset is_a: CL:0000115 ! endothelial cell +relationship: RO:0000053 PATO:0002254 ! has characteristic flattened property_value: terms:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T03:31:25Z @@ -1837,6 +1845,7 @@ subset: human_subset subset: mouse_subset xref: ZFA:0007084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: BFO:0000002 +is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011012 ! neural crest cell relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell @@ -1940,7 +1949,6 @@ subset: cellxgene_subset subset: human_subset subset: mouse_subset is_a: BFO:0000002 -is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002202 CL:0000034 ! develops from stem cell @@ -2475,6 +2483,7 @@ is_a: GO:0140096 ! catalytic activity, acting on a protein is_a: GO:0140101 ! catalytic activity, acting on a tRNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0000262 @@ -2661,21 +2670,6 @@ intersection_of: RO:0002297 UBERON:0001049 ! results in formation of anatomical relationship: BFO:0000050 GO:0021915 ! part of neural tube development relationship: RO:0002297 UBERON:0001049 ! results in formation of anatomical entity neural tube -[Term] -id: GO:0001977 -name: renal system process involved in regulation of blood volume -namespace: biological_process -def: "A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system." [GOC:dph, GOC:tb, ISBN:0721643949] -subset: gocheck_obsoletion_candidate -synonym: "renal blood volume control of blood pressure" RELATED [] -synonym: "renal regulation of blood volume" RELATED [GOC:dph, GOC:tb] -is_a: GO:0003071 ! renal system process involved in regulation of systemic arterial blood pressure -relationship: BFO:0000050 GO:0050878 ! part of regulation of body fluid levels -property_value: RO:0002161 NCBITaxon:2 -property_value: RO:0002161 NCBITaxon:2157 -property_value: RO:0002161 NCBITaxon:4896 -property_value: RO:0002161 NCBITaxon:4932 - [Term] id: GO:0001990 name: regulation of systemic arterial blood pressure by hormone @@ -2931,7 +2925,6 @@ id: GO:0003093 name: regulation of glomerular filtration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule." [GOC:mtg_cardio] -is_a: GO:0001977 ! renal system process involved in regulation of blood volume is_a: GO:0098801 ! regulation of renal system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003094 ! regulates glomerular filtration @@ -2987,6 +2980,7 @@ subset: goslim_yeast synonym: "molecular function" EXACT [] disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process +property_value: IAO:0000116 "This is the same as GO molecular function" xsd:string [Term] id: GO:0003824 @@ -3023,6 +3017,9 @@ synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 +union_of: GO:0032991 ! protein-containing complex +union_of: GO:0044423 ! virion component +union_of: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0008150 ! biological_process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI @@ -3071,7 +3068,8 @@ namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex -relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa +relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa +relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0005587 @@ -3856,6 +3854,7 @@ synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process +relationship: BFO:0000051 GO:0003674 ! has part molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI creation_date: 2012-09-19T15:05:24Z @@ -4211,9 +4210,9 @@ subset: goslim_chembl subset: goslim_pir subset: goslim_yeast synonym: "enzyme transport" NARROW [] +is_a: GO:0006810 ! transport is_a: GO:0008104 ! intracellular protein localization is_a: GO:0045184 ! establishment of protein localization -is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 PR:000000001 ! has primary input protein @@ -4347,10 +4346,10 @@ subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" -xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016746 @@ -4367,6 +4366,7 @@ xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurin xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" is_a: GO:0016740 ! transferase activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0016755 @@ -4376,6 +4376,7 @@ def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) synonym: "transferase activity, transferring amino-acyl groups" EXACT [] xref: EC:2.3.2.- is_a: GO:0016746 ! acyltransferase activity +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30193" xsd:anyURI [Term] id: GO:0017145 @@ -4603,6 +4604,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] @@ -4611,6 +4613,7 @@ is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] @@ -4618,6 +4621,7 @@ id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:18391171] +subset: gocheck_do_not_annotate synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly @@ -4625,6 +4629,7 @@ is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI [Term] id: GO:0030054 @@ -4922,6 +4927,7 @@ is_a: GO:0005575 ! cellular_component disjoint_from: GO:0044423 ! virion component disjoint_from: GO:0110165 ! cellular anatomical structure relationship: BFO:0000051 PR:000000001 ! has part protein +property_value: IAO:0000116 "This is not covalently bonded, which conflicts with changes to the parent definition." xsd:string [Term] id: GO:0033036 @@ -5070,7 +5076,7 @@ relationship: BFO:0000051 GO:0034220 ! has part monoatomic ion transmembrane tra id: GO:0042592 name: homeostatic process namespace: biological_process -def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] +def: "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." [PMID:26265027] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse @@ -5081,6 +5087,7 @@ synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological_process +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/31175" xsd:anyURI [Term] id: GO:0042644 @@ -5147,6 +5154,7 @@ id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, PMID:16318917] +subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon @@ -5159,6 +5167,7 @@ synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: BFO:0000050 CL:0000000 ! part of cell +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23013" xsd:anyURI property_value: skos:prefLabel "cell projection" xsd:string [Term] @@ -6114,16 +6123,6 @@ relationship: RO:0002339 GO:0005576 ! has target end location extracellular regi relationship: RO:0004009 PR:000000001 ! has primary input protein creation_date: 2010-02-25T04:00:13Z -[Term] -id: GO:0071705 -name: nitrogen compound transport -namespace: biological_process -def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] -subset: gocheck_obsoletion_candidate -is_a: BFO:0000003 -is_a: GO:0006810 ! transport -creation_date: 2010-03-08T03:56:28Z - [Term] id: GO:0071826 name: protein-RNA complex organization @@ -6300,15 +6299,16 @@ def: "A collagen trimer that forms networks." [PMID:21421911] is_a: BFO:0000004 is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer -intersection_of: BFO:0000050 GO:0098645 ! part of collagen network -relationship: BFO:0000050 GO:0098645 ! part of collagen network +intersection_of: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens +relationship: BFO:0000050 GO:0098645 ! part of complex of network-forming collagens [Term] id: GO:0098643 -name: fibrillar collagen +name: fibrillar collagen complex namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175] synonym: "banded collagen fibril" EXACT [] +synonym: "fibrillar collagen" EXACT [] is_a: GO:0098644 ! complex of collagen trimers relationship: BFO:0000050 GO:0140152 ! part of collagenous component of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI @@ -6329,10 +6329,12 @@ property_value: skos:prefLabel "complex of collagen trimers" xsd:string [Term] id: GO:0098645 -name: collagen network +name: complex of network-forming collagens namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] +synonym: "collagen network" EXACT [] is_a: GO:0098644 ! complex of collagen trimers +property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30938" xsd:anyURI [Term] id: GO:0098793 @@ -6434,6 +6436,8 @@ subset: goslim_pir synonym: "cellular anatomical entity" EXACT [] is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure +property_value: IAO:0000116 "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." xsd:string +property_value: IAO:0000116 "Overlaps with some cellular components from GO" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28978" xsd:anyURI @@ -6588,7 +6592,7 @@ id: GO:0140154 name: chicken-wire-like collagen network namespace: cellular_component def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942] -is_a: GO:0098645 ! collagen network +is_a: GO:0098645 ! complex of network-forming collagens relationship: BFO:0000050 GO:0140143 ! part of collagenous component of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI @@ -6859,6 +6863,22 @@ xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: skos:prefLabel "Eukaryota" xsd:string +[Term] +id: NCBITaxon:28009 +name: Choanoflagellata +namespace: ncbi_taxonomy +synonym: "Choanoflagellatea" RELATED synonym [] +synonym: "choanoflagellates" EXACT genbank_common_name [] +synonym: "choanoflagellates" RELATED blast_name [] +synonym: "Choanoflagellida" RELATED synonym [] +synonym: "Choanomonada" RELATED synonym [] +synonym: "Choanozoa" RELATED synonym [] +xref: GC_ID:1 +xref: PMID:27765632 +is_a: NCBITaxon:33154 ! Opisthokonta +disjoint_from: NCBITaxon:33208 ! Metazoa +disjoint_from: NCBITaxon:4751 ! Fungi + [Term] id: NCBITaxon:314146 name: Euarchontoglires @@ -7344,6 +7364,14 @@ subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality +[Term] +id: PATO:0001591 +name: curvature +namespace: quality +def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] +subset: attribute_slim +is_a: PATO:0000052 ! shape + [Term] id: PATO:0001690 name: contractile @@ -7531,6 +7559,18 @@ is_a: PATO:0001018 ! physical quality property_value: terms:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-03-15T04:35:27Z +[Term] +id: PATO:0002254 +name: flattened +namespace: quality +def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] +comment: Becoming flat but not necessarily completely flat. +subset: value_slim +synonym: "compressed" RELATED [] +is_a: PATO:0001591 ! curvature +property_value: terms:contributor https://orcid.org/0000-0002-2061-091X +creation_date: 2010-08-16T03:59:34Z + [Term] id: PATO:0002266 name: 3-D shape @@ -17003,7 +17043,7 @@ xref: NCIT:C32339 xref: NIF_Subcellular:sao7547390221 is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: RO:0002473 GO:0005581 ! composed primarily of collagen trimer -relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen +relationship: RO:0002473 GO:0098643 ! composed primarily of fibrillar collagen complex property_value: seeAlso UBERON:0007377 property_value: skos:prefLabel "collection of collagen fibrils" xsd:string diff --git a/subsets/kidney_upper_slim.owl b/subsets/kidney_upper_slim.owl index 2832aef43..b4482195b 100644 --- a/subsets/kidney_upper_slim.owl +++ b/subsets/kidney_upper_slim.owl @@ -14,8 +14,8 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - - 2025-12-17 + + 2026-03-17 @@ -251,7 +251,6 @@ WHERE { An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has narrow synonym - has_narrow_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/19 @@ -2774,14 +2773,7 @@ Each of these 3 primitives can be composed to yield a cross-product of different - - - - - - - @@ -2798,13 +2790,12 @@ Stem cells have numerous potential applications in medicine, including the treat CALOHA:TS-2086 FMA:63368 ZFA:0005957 - animal stem cell + animal stem cell - This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. stem cell https://cellxgene.cziscience.com/cellguide/CL_0000034 stem cell @@ -2911,6 +2902,7 @@ Stem cells have numerous potential applications in medicine, including the treat + @@ -3817,7 +3809,26 @@ Blood vessel endothelial cells are sensitive to various stimuli, including shear + + + + + + + + + + + + + + + + + + An epithelial cell that has a flattened morphology. + 2025-12-16T15:56:39Z CALOHA:TS-1249 ZFA:0009039 @@ -4285,6 +4296,7 @@ Apart from their role in tissue maintenance and repair, MSCs are integral to the A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + BTO:0000888 BTO:0000902 CALOHA:TS-2032 @@ -4298,6 +4310,7 @@ Apart from their role in tissue maintenance and repair, MSCs are integral to the + muscle cell muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -4859,6 +4872,7 @@ In addition to their role in oxygen transport, erythrocytes also play a key role + @@ -6670,6 +6684,7 @@ Furthermore, pericytes have demonstrated functions in regulating immune and infl + @@ -8275,6 +8290,12 @@ The balance between cell proliferation and differentiation in embryonic cells is + + + + + + A squamous shaped endothelial cell. 2011-07-08T03:31:25Z @@ -8377,6 +8398,7 @@ Renal principal cells are also involved in the regulation of sodium and potassiu + @@ -8660,7 +8682,6 @@ Disorders or aberrations in the development or migration of the neural crest cel - @@ -10287,6 +10308,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. https://github.com/geneontology/go-ontology/issues/22192 https://github.com/geneontology/go-ontology/issues/25493 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.12 MetaCyc:PEPTIDYLTRANSFERASE-RXN Reactome:R-HSA-156912 @@ -10880,46 +10902,6 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - - - - - - - - - A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system. - - - - - biological_process - renal blood volume control of blood pressure - renal regulation of blood volume - GO:0001977 - - renal system process involved in regulation of blood volume - - - - - A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system. - GOC:dph - GOC:tb - ISBN:0721643949 - - - - - renal regulation of blood volume - GOC:dph - GOC:tb - - - - @@ -11548,7 +11530,6 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - @@ -11668,6 +11649,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. + This is the same as GO molecular function molecular function molecular_function GO:0003674 @@ -11730,6 +11712,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + @@ -11849,10 +11840,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component @@ -13805,6 +13802,12 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. https://github.com/geneontology/go-ontology/issues/24968 2012-09-19T15:05:24Z @@ -14082,6 +14085,30 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + + + + + + + + + + + + + + + A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. @@ -14130,6 +14157,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + @@ -14200,6 +14237,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + @@ -14270,6 +14317,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + @@ -14306,6 +14363,70 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. @@ -14747,9 +14868,9 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + - The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. enzyme transport biological_process @@ -15051,10 +15172,10 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + https://github.com/geneontology/go-ontology/issues/30193 EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 - Reactome:R-HSA-5333607 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function @@ -15089,12 +15210,6 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 - - - - Reactome:R-HSA-5333607 - GSSeH combines with bGalNAc derivative to form GSSebGalNac - @@ -15116,6 +15231,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 @@ -15166,6 +15282,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). + https://github.com/geneontology/go-ontology/issues/30193 EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function @@ -15808,12 +15925,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 https://github.com/geneontology/go-ontology/issues/26279 cell projection organisation biological_process cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 + cell projection organization @@ -15863,10 +15982,12 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 formation of a cell surface projection biological_process cell projection biogenesis GO:0030031 + cell projection assembly @@ -16668,6 +16789,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + This is not covalently bonded, which conflicts with changes to the parent definition. macromolecular complex macromolecule complex protein containing complex @@ -17196,7 +17318,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - Any biological process involved in the maintenance of an internal steady state. + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + https://github.com/geneontology/go-ontology/issues/31175 homeostasis activation of homeostatic process inhibition of homeostatic process @@ -17213,9 +17336,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - Any biological process involved in the maintenance of an internal steady state. - GOC:jl - ISBN:0395825172 + Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. + PMID:26265027 @@ -17323,6 +17445,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + @@ -17431,11 +17563,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A prolongation or process extending from a cell, e.g. a flagellum or axon. + https://github.com/geneontology/go-ontology/issues/23013 cell process cellular process cellular projection cellular_component GO:0042995 + @@ -20013,27 +20147,6 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - - - - The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. - 2010-03-08T03:56:28Z - biological_process - GO:0071705 - - nitrogen compound transport - - - - - The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. - GOC:mah - - - - @@ -20572,9 +20685,10 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://github.com/geneontology/go-ontology/issues/29474 https://github.com/geneontology/go-ontology/issues/30146 banded collagen fibril + fibrillar collagen cellular_component GO:0098643 - fibrillar collagen + fibrillar collagen complex fibrillar collagen @@ -20639,9 +20753,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A supramolecular complex that consists of collagen triple helices associated to form a network. + https://github.com/geneontology/go-ontology/issues/30938 + collagen network cellular_component GO:0098645 - collagen network + complex of network-forming collagens @@ -20931,6 +21047,9 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes. + Overlaps with some cellular components from GO https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 https://github.com/geneontology/go-ontology/issues/28978 @@ -22043,6 +22162,63 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + GC_ID:1 + PMID:27765632 + choanoflagellates + ncbi_taxonomy + Choanoflagellatea + Choanoflagellida + Choanomonada + Choanozoa + choanoflagellates + NCBITaxon:28009 + Choanoflagellata + + + + + choanoflagellates + + + + + + Choanoflagellatea + + + + + + Choanoflagellida + + + + + + Choanomonada + + + + + + Choanozoa + + + + + + choanoflagellates + + + + + @@ -23133,6 +23309,25 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + quality + PATO:0001591 + + curvature + + + + + A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. + WordNet:WordNet + + + + @@ -23539,6 +23734,29 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + + 2010-08-16T03:59:34Z + quality + compressed + PATO:0002254 + + Becoming flat but not necessarily completely flat. + flattened + + + + + A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. + PATOC:CVS + + + + @@ -25261,7 +25479,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -25314,14 +25532,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext ureter https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + GO @@ -25371,7 +25589,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -25418,14 +25636,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext urethra https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png - + - + Wikipedia @@ -26230,7 +26448,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -26279,14 +26497,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg https://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg - + - + FMA MA @@ -26541,15 +26759,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + - + @@ -26580,34 +26798,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext metanephros - + - + - + - + definitional - + GO - + ISBN:9780878932504 @@ -26722,8 +26940,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]. BTO:0001646 EHDAA2:0002140 @@ -26746,11 +26964,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext ureteric bud - + - + @@ -26763,13 +26981,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 - + ISBN:9780878932504 @@ -26879,7 +27097,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -26890,14 +27108,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext membrane organ membrane organ - + - + FMA-def @@ -27666,7 +27884,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -27708,14 +27926,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext gastrula stage gastrula stage - + - + BILS @@ -28126,8 +28344,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -28153,24 +28371,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext cloaca cloaca - + - + - + ZFA - + AAO @@ -28212,8 +28430,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -28231,24 +28449,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext embryonic cloaca embryonic cloaca - + - + - + EHDAA2 - + EHDAA2 @@ -28272,7 +28490,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -28304,14 +28522,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext primitive urogenital sinus http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + - + MP-def @@ -28610,15 +28828,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - - + + A fluid that is composed of blood plasma and erythrocytes. @@ -28657,34 +28875,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext blood blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -30609,7 +30827,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -30644,14 +30862,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext abdomen abdomen - + - + MA @@ -30880,7 +31098,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. AAO:0000137 BILA:0000036 @@ -30915,14 +31133,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -30962,7 +31180,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. AAO:0000139 BILA:0000038 @@ -30997,14 +31215,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -31045,7 +31263,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The middle germ layer of the embryo, between the endoderm and ectoderm. AAO:0000304 @@ -31085,14 +31303,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + - + Bgee:AN @@ -31253,7 +31471,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -31294,7 +31512,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://github.com/obophenotype/uberon/issues/685 proctodeum - + @@ -31307,7 +31525,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -31369,7 +31587,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -31434,14 +31652,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb - + - + MA @@ -32315,7 +32533,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -32366,14 +32584,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -32433,7 +32651,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. @@ -32478,7 +32696,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext central nervous system central nervous system - + @@ -32492,7 +32710,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Bgee:AN @@ -32690,7 +32908,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -32724,14 +32942,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext hindgut http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png - + - + Wikipedia @@ -33232,7 +33450,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -33257,14 +33475,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -33379,14 +33597,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -33437,24 +33655,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal pelvis https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg - + - + - + MA - + FMA @@ -33500,7 +33718,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -33535,14 +33753,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://cdn.humanatlas.io/digital-objects/ref-organ/kidney-male-right/v1.3/assets/3d-vh-m-kidney-r.glb https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg - + - + FMA @@ -33578,7 +33796,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -33622,14 +33840,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal corpuscle https://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg - + - + MA ZFA @@ -33704,7 +33922,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -33745,14 +33963,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext glomerular capsule http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg - + - + Wikipedia @@ -33842,11 +34060,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -33888,7 +34106,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext nephron tubule - + @@ -33897,14 +34115,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + GO MA ZFA @@ -33918,7 +34136,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA @@ -34142,7 +34360,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -34188,7 +34406,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext https://cdn.humanatlas.io/digital-objects/ref-organ/urinary-bladder-male/v1.2/assets/3d-vh-m-urinary-bladder.glb https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + @@ -34201,7 +34419,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + FMA @@ -34332,14 +34550,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]. kidney terms require review for cross-vertebrate compatibility and developmental relationships. @@ -34369,24 +34587,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext nephron http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + - + FMA - + Bgee:AN @@ -34437,14 +34655,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -34479,11 +34697,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext proximal convoluted tubule http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + @@ -34496,13 +34714,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + GO - + Wikipedia @@ -34633,7 +34851,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -34659,7 +34877,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext descending limb of loop of Henle http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + @@ -34672,7 +34890,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + FMA @@ -34696,14 +34914,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -34740,11 +34958,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext proximal straight tubule - + - + @@ -34757,13 +34975,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + MA - + MA @@ -34805,7 +35023,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -34840,7 +35058,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext distal convoluted tubule https://upload.wikimedia.org/wikipedia/commons/2/21/Kidney_nephron.png - + @@ -34853,7 +35071,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EMAPA GO MA-modified-from-isa @@ -34975,7 +35193,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The anus and surrounding regions. Encompasses both internal and external regions, where present. EFO:0000847 EHDAA2:0000122 @@ -35000,14 +35218,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext anal region http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png - + - + cjm @@ -35229,7 +35447,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -35251,14 +35469,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext kidney arcuate artery https://upload.wikimedia.org/wikipedia/commons/8/87/2610_The_Kidney.jpg - + - + MA @@ -35294,7 +35512,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + A tube extending from the mouth to the anus. @@ -35332,14 +35550,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext digestive tract digestive tract - + - + NCBIBook:NBK10107 @@ -36057,8 +36275,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -36071,7 +36289,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -36125,34 +36343,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -37025,14 +37243,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + @@ -37071,24 +37289,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext kidney - + - + - + FMA - + definitional @@ -37123,8 +37341,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -37160,11 +37378,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 pronephros - + - + @@ -37177,13 +37395,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + OG - + ZFA @@ -37584,7 +37802,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -37603,7 +37821,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]. BTO:0005157 @@ -37624,24 +37842,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext juxtaglomerular apparatus - + - + - + MA - + GO @@ -37763,8 +37981,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + The tissue comprised of mesangial cells that fill the triangular space between the macula densa and the afferent and efferent arterioles of the juxtaglomerular apparatus. EMAPA:28278 FMA:84141 @@ -37774,24 +37992,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext EDITOR_NOTE check MA part_ofs - should be spatially disjoint from renal glomerulus? extraglomerular mesangium - + - + - + MA - + MA @@ -37809,7 +38027,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -37845,14 +38063,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext coelemic cavity lumen coelemic cavity lumen - + - + definitional @@ -37948,8 +38166,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + @@ -37999,11 +38217,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -38022,13 +38240,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA - + EHDAA2 @@ -38069,7 +38287,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. mesodermal cluster @@ -38107,7 +38325,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -38120,7 +38338,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA @@ -38238,8 +38456,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]. BTO:0003940 @@ -38256,24 +38474,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext macula densa - + - + - + MA - + GO @@ -38297,16 +38515,16 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - + + + - + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. AAO:0010578 BTO:0001764 @@ -38339,45 +38557,45 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + BTO - + PMID:11523831 - + PMID:11523831 @@ -38816,8 +39034,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + Anatomical system that is involved in the production of hematopoietic cells. @@ -38858,24 +39076,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext hematopoietic system hematopoietic system - + - + - + FMA - + definitional @@ -39169,7 +39387,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -39188,7 +39406,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. AAO:0011086 EFO:0001982 @@ -39211,14 +39429,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext presomitic mesoderm presomitic mesoderm - + - + Bgee:AN @@ -39258,8 +39476,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. AAO:0011088 NCIT:C34279 @@ -39277,11 +39495,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] pronephric duct - + - + @@ -39294,13 +39512,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Wikipedia - + XAO @@ -39408,9 +39626,9 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - + + + @@ -39449,34 +39667,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext intermediate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + - + AAO - + EMAPA - + XAO @@ -39586,7 +39804,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. Consider adding subclasses for male and female specific variants TODO - mesonephric portion of the nephric duct @@ -39615,7 +39833,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext mesonephric duct http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + @@ -39628,7 +39846,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -39682,8 +39900,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. AAO:0011072 BTO:0001765 @@ -39712,24 +39930,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + Wikipedia - + Bgee:AN @@ -39775,7 +39993,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. AAO:0010568 EFO:0003515 @@ -39801,7 +40019,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -39814,7 +40032,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Bgee:AN @@ -39861,7 +40079,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -39900,7 +40118,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -39913,7 +40131,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 VHOG @@ -39964,15 +40182,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. AAO:0011044 @@ -39989,15 +40207,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext heart primordium heart primordium - + - + - + @@ -40010,19 +40228,19 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA - + ZFA - + XAO @@ -40051,8 +40269,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. AAO:0010571 AEO:0000212 @@ -40076,11 +40294,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -40099,13 +40317,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + VHOG:0000680 - + ZFA @@ -40344,7 +40562,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -40369,14 +40587,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] metanephric mesenchyme - + - + ISBN:9780878932504 @@ -41062,7 +41280,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults EHDAA:251 @@ -41077,14 +41295,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext intraembryonic coelom intraembryonic coelom - + - + Wikipedia @@ -41664,8 +41882,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the loop of Henle. It has a brush border epithelial morphology[GO]. TODO - ensure definition works across species. @@ -41681,24 +41899,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext proximal tubule - + - + - + GO - + GO @@ -41756,7 +41974,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The intermediate tubule is a nephron tubule that lies between the proximal and distal tubules. TODO - check for applicability across species FMA:17718 @@ -41765,14 +41983,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0004136 intermediate tubule - + - + FMA @@ -41848,8 +42066,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. XAO:0004185 first heart field @@ -41861,24 +42079,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext primary heart field primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -41931,7 +42149,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + An epithelial tube that will give rise to the mature heart. AAO:0010411 EFO:0003526 @@ -41950,14 +42168,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext heart tube heart tube - + - + ZFA-modified @@ -42176,8 +42394,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. EMAPA:27681 ZFA:0005588 @@ -42186,24 +42404,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext comma-shaped body - + - + - + cjm - + ZFA @@ -42226,8 +42444,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. TODO EMAPA:27756 @@ -42238,24 +42456,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext S-shaped body - + - + - + cjm - + GO @@ -42661,7 +42879,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -42698,14 +42916,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext glomerular capillary - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -43238,7 +43456,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -43280,14 +43498,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal afferent arteriole http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + Wikipedia @@ -43647,7 +43865,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. AAO:0011129 TAO:0001890 @@ -43661,14 +43879,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext skeletal element skeletal element - + - + VSAO @@ -43696,7 +43914,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -43729,14 +43947,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext articular system articular system - + - + FMA @@ -44032,7 +44250,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -44053,14 +44271,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext somatopleure http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png - + - + EHDAA2 @@ -44127,9 +44345,9 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - - + + + @@ -44148,34 +44366,34 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext urogenital fold - + - + - + - + EHDAA2 - + Wikipedia - + EHDAA2 @@ -44633,21 +44851,21 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Missing definition for term UBERON:0005095. Please replace it using linked reference. class added for consistency with GO - consider merging with kidney mesenchyme. kidney anlage UBERON:0005095 kidney rudiment - + - + GO @@ -44761,7 +44979,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]. BTO:0004539 @@ -44778,14 +44996,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal connecting tubule http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + Wikipedia @@ -45509,7 +45727,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -45525,14 +45743,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext trunk mesenchyme trunk mesenchyme - + - + EHDAA2 @@ -45650,7 +45868,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. EHDAA2:0001512 EHDAA:424 @@ -45668,14 +45886,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext primitive heart tube primitive heart tube - + - + ZFA @@ -45703,7 +45921,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -45730,7 +45948,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext gonad primordium gonad primordium - + @@ -45743,7 +45961,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + ZFA @@ -45801,14 +46019,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + A mesoderm that has the potential to develop into a pronephros. AAO:0011090 EFO:0003479 @@ -45825,24 +46043,24 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney pronephric mesoderm - + - + - + ZFA - + Bgee:AN @@ -45889,7 +46107,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -45905,14 +46123,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext glomerular tuft - + - + Wikipedia @@ -46153,7 +46371,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -46180,14 +46398,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext glomerular basement membrane http://upload.wikimedia.org/wikipedia/commons/d/de/PhysiologieGlom%C3%A9rulaire.png - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -46271,7 +46489,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -46281,7 +46499,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext developing mesenchymal condensation developing mesenchymal condensation - + @@ -46300,7 +46518,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + AEO-modified-relation @@ -46400,7 +46618,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -46438,14 +46656,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext cloacal membrane http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png - + - + Wikipedia @@ -46479,7 +46697,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB EHDAA2:0001278 @@ -46493,7 +46711,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext notochordal plate notochordal plate - + @@ -46506,7 +46724,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -46535,7 +46753,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -46552,14 +46770,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext notochordal process notochordal process - + - + EHDAA2 @@ -47073,12 +47291,12 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + A region of nephron tubule that is part of a cortex of kidney. EMAPA:18976 MA:0002609 @@ -47087,14 +47305,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0006853 renal cortex tubule - + - + MA @@ -47770,7 +47988,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -47796,7 +48014,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext presumptive paraxial mesoderm presumptive paraxial mesoderm - + @@ -47812,7 +48030,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + https://github.com/obophenotype/uberon/issues/1277 @@ -47973,7 +48191,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -47981,7 +48199,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext dense mesenchyme tissue dense mesenchyme tissue - + @@ -47994,7 +48212,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + AEO @@ -48060,7 +48278,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -48080,14 +48298,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext layer of synovial tissue layer of synovial tissue - + - + BTO @@ -48470,7 +48688,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -48487,14 +48705,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext vascular system vascular system - + - + MA @@ -48619,7 +48837,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -48656,14 +48874,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext pelvic girdle skeleton http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray242.png - + - + PMID:21455939 @@ -48738,12 +48956,12 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + The functional tissue of the kidney, consisting of the nephrons. BTO:0003604 FMA:15574 @@ -48753,7 +48971,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0008987 renal parenchyma - + @@ -48766,7 +48984,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + FMA @@ -48837,7 +49055,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -48853,14 +49071,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext entire embryonic mesenchyme entire embryonic mesenchyme - + - + EHDAA2 @@ -48979,7 +49197,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme @@ -48987,14 +49205,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext trunk paraxial mesoderm trunk paraxial mesoderm - + - + EHDAA2 @@ -49164,7 +49382,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -49174,14 +49392,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext anterior lateral plate mesoderm anterior lateral plate mesoderm - + - + ZFA @@ -49500,7 +49718,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -49518,14 +49736,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext future cardiac atrium future cardiac atrium - + - + ZFA @@ -49669,7 +49887,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -49683,7 +49901,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext mesenchyme from somatopleure mesenchyme from somatopleure - + @@ -49696,7 +49914,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -49712,7 +49930,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -49722,14 +49940,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext microcirculatory vessel microcirculatory vessel - + - + ZFA @@ -49763,7 +49981,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -49778,7 +49996,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0010532 primitive nephron - + @@ -49791,7 +50009,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2 @@ -49807,7 +50025,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -49817,7 +50035,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0010536 nephron progenitor - + @@ -49830,7 +50048,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + cjm @@ -50073,8 +50291,8 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. FMA:23879 SCTID:129140006 @@ -50086,11 +50304,11 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext subdivision of skeleton subdivision of skeleton - + - + @@ -50103,13 +50321,13 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + UBERONREF:0000003 - + VSAO @@ -50203,7 +50421,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -50214,7 +50432,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton postcranial axial skeletal system - + @@ -50227,7 +50445,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + cjm @@ -50264,7 +50482,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + Subdivision of urinary system which consists of the kidney and the ureters. FMA:45658 @@ -50276,14 +50494,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext upper urinary tract - + - + FMA-abduced-lr @@ -50725,7 +50943,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -50739,14 +50957,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts embryonic cloacal fold - + - + EHDAA2 @@ -50769,20 +50987,20 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2:0004588 UBERON:0012361 internal anal region internal anal region - + - + EHDAA2 @@ -50792,20 +51010,20 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + EHDAA2:0004589 UBERON:0012469 external anal region external anal region - + - + EHDAA2 @@ -50944,7 +51162,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The precursor of the urethra. SCTID:361531004 Wikipedia:Urethral_groove @@ -50954,14 +51172,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext UBERON:0013241 embryonic urethral groove - + - + Wikipedia @@ -51554,7 +51772,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + @@ -51577,7 +51795,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext entire extraembryonic component entire extraembryonic component - + @@ -51590,7 +51808,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + AEO @@ -52061,7 +52279,7 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. NCIT:C54419 @@ -52071,14 +52289,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext renal pelvis/ureter - + - + NCIT @@ -52377,14 +52595,14 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + definitional - + @@ -52488,15 +52706,15 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext - + - + AAO https://github.com/geneontology/go-ontology/issues/16143 - + @@ -52777,6 +52995,40 @@ Furthermore, the kidney loop of Henle descending limb epithelial cells are inext + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/subsets/kidney_upper_slim.tsv b/subsets/kidney_upper_slim.tsv index 1bd57d771..c193e7f53 100644 --- a/subsets/kidney_upper_slim.tsv +++ b/subsets/kidney_upper_slim.tsv @@ -156,7 +156,6 @@ http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation http://purl.obolibrary.org/obo/GO_0001841 neural tube formation -http://purl.obolibrary.org/obo/GO_0001977 renal system process involved in regulation of blood volume http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone http://purl.obolibrary.org/obo/GO_0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin http://purl.obolibrary.org/obo/GO_0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure @@ -389,7 +388,6 @@ http://purl.obolibrary.org/obo/GO_0070293 renal absorption http://purl.obolibrary.org/obo/GO_0070295 renal water absorption http://purl.obolibrary.org/obo/GO_0070925 organelle assembly http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region -http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis http://purl.obolibrary.org/obo/GO_0071944 cell periphery @@ -403,9 +401,9 @@ http://purl.obolibrary.org/obo/GO_0097254 renal tubular secretion http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer -http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen +http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers -http://purl.obolibrary.org/obo/GO_0098645 collagen network +http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex @@ -448,6 +446,7 @@ http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota +http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda @@ -497,6 +496,7 @@ http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0001579 contractility +http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0001873 cylindrical @@ -516,6 +516,7 @@ http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0002124 laminar http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance +http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002318 superelliptic