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| 1 | +package org.cbioportal.application.rest.vcolumnstore; |
| 2 | + |
| 3 | +import io.swagger.v3.oas.annotations.Operation; |
| 4 | +import io.swagger.v3.oas.annotations.Parameter; |
| 5 | +import io.swagger.v3.oas.annotations.media.ArraySchema; |
| 6 | +import io.swagger.v3.oas.annotations.media.Content; |
| 7 | +import io.swagger.v3.oas.annotations.media.Schema; |
| 8 | +import io.swagger.v3.oas.annotations.responses.ApiResponse; |
| 9 | +import jakarta.validation.Valid; |
| 10 | +import jakarta.validation.constraints.Max; |
| 11 | +import jakarta.validation.constraints.Min; |
| 12 | +import org.cbioportal.application.rest.mapper.SampleMapper; |
| 13 | +import org.cbioportal.application.rest.response.SampleDTO; |
| 14 | +import org.cbioportal.legacy.model.CancerStudy; |
| 15 | +import org.cbioportal.domain.sample.Sample; |
| 16 | +import org.cbioportal.domain.sample.usecase.SampleUseCases; |
| 17 | +import org.cbioportal.legacy.model.meta.BaseMeta; |
| 18 | +import org.cbioportal.legacy.service.StudyService; |
| 19 | +import org.cbioportal.legacy.service.exception.PatientNotFoundException; |
| 20 | +import org.cbioportal.legacy.service.exception.SampleNotFoundException; |
| 21 | +import org.cbioportal.legacy.service.exception.StudyNotFoundException; |
| 22 | +import org.cbioportal.legacy.utils.security.AccessLevel; |
| 23 | +import org.cbioportal.legacy.utils.security.PortalSecurityConfig; |
| 24 | +import org.cbioportal.legacy.web.parameter.Direction; |
| 25 | +import org.cbioportal.legacy.web.parameter.HeaderKeyConstants; |
| 26 | +import org.cbioportal.legacy.web.parameter.PagingConstants; |
| 27 | +import org.cbioportal.legacy.web.parameter.SampleFilter; |
| 28 | +import org.cbioportal.legacy.web.parameter.sort.SampleSortBy; |
| 29 | +import org.cbioportal.shared.enums.ProjectionType; |
| 30 | +import org.springframework.beans.factory.annotation.Value; |
| 31 | +import org.springframework.context.annotation.Profile; |
| 32 | +import org.springframework.http.HttpHeaders; |
| 33 | +import org.springframework.http.HttpStatus; |
| 34 | +import org.springframework.http.MediaType; |
| 35 | +import org.springframework.http.ResponseEntity; |
| 36 | +import org.springframework.security.access.prepost.PreAuthorize; |
| 37 | +import org.springframework.validation.annotation.Validated; |
| 38 | +import org.springframework.web.bind.annotation.GetMapping; |
| 39 | +import org.springframework.web.bind.annotation.PathVariable; |
| 40 | +import org.springframework.web.bind.annotation.PostMapping; |
| 41 | +import org.springframework.web.bind.annotation.RequestBody; |
| 42 | +import org.springframework.web.bind.annotation.RequestMapping; |
| 43 | +import org.springframework.web.bind.annotation.RequestParam; |
| 44 | +import org.springframework.web.bind.annotation.RestController; |
| 45 | + |
| 46 | +import java.util.List; |
| 47 | + |
| 48 | +@RestController |
| 49 | +@RequestMapping("/api/column-store") |
| 50 | +@Validated |
| 51 | +@Profile("clickhouse") |
| 52 | +public class ColumnStoreSampleController { |
| 53 | + public static final int SAMPLE_MAX_PAGE_SIZE = 10000000; |
| 54 | + private static final String SAMPLE_DEFAULT_PAGE_SIZE = "10000000"; |
| 55 | + |
| 56 | + private final SampleUseCases sampleUseCases; |
| 57 | + |
| 58 | + private final StudyService studyService; |
| 59 | + |
| 60 | + @Value("${authenticate}") |
| 61 | + private String authenticate; |
| 62 | + |
| 63 | + public ColumnStoreSampleController( |
| 64 | + SampleUseCases sampleUseCases, |
| 65 | + StudyService studyService |
| 66 | + ) { |
| 67 | + this.sampleUseCases = sampleUseCases; |
| 68 | + this.studyService = studyService; |
| 69 | + } |
| 70 | + |
| 71 | + @GetMapping(value = "/samples", produces = MediaType.APPLICATION_JSON_VALUE) |
| 72 | + @Operation(description = "Get all samples matching keyword") |
| 73 | + @ApiResponse( |
| 74 | + responseCode = "200", |
| 75 | + description = "OK", |
| 76 | + content = @Content(array = @ArraySchema(schema = @Schema(implementation = Sample.class))) |
| 77 | + ) |
| 78 | + public ResponseEntity<List<SampleDTO>> getSamplesByKeyword( |
| 79 | + @Parameter(description = "Search keyword that applies to the study ID") |
| 80 | + @RequestParam(required = false) |
| 81 | + String keyword, |
| 82 | + @Parameter(description = "Level of detail of the response") |
| 83 | + @RequestParam(defaultValue = "SUMMARY") |
| 84 | + ProjectionType projection, |
| 85 | + @Parameter(description = "Page size of the result list") |
| 86 | + @Max(PagingConstants.MAX_PAGE_SIZE) |
| 87 | + @Min(PagingConstants.MIN_PAGE_SIZE) |
| 88 | + @RequestParam(defaultValue = PagingConstants.DEFAULT_PAGE_SIZE) |
| 89 | + Integer pageSize, |
| 90 | + @Parameter(description = "Page number of the result list") |
| 91 | + @Min(PagingConstants.MIN_PAGE_NUMBER) |
| 92 | + @RequestParam(defaultValue = PagingConstants.DEFAULT_PAGE_NUMBER) |
| 93 | + Integer pageNumber, |
| 94 | + @Parameter(description = "Name of the property that the result list is sorted by") |
| 95 | + @RequestParam(required = false) |
| 96 | + SampleSortBy sortBy, |
| 97 | + @Parameter(description = "Direction of the sort") |
| 98 | + @RequestParam(defaultValue = "ASC") |
| 99 | + Direction direction |
| 100 | + ) { |
| 101 | + String sort = sortBy == null ? null : sortBy.getOriginalValue(); |
| 102 | + List<String> studyIds = null; |
| 103 | + |
| 104 | + // TODO is there a better way to do this? something like @PreAuthorize? |
| 105 | + // (this code segment is duplicate of the legacy SampleController) |
| 106 | + if (PortalSecurityConfig.userAuthorizationEnabled(authenticate)) { |
| 107 | + /* |
| 108 | + If using auth, filter the list of samples returned using the list of study ids the |
| 109 | + user has access to. If the user has access to no studies, the endpoint should not 403, |
| 110 | + but instead return an empty list. |
| 111 | + */ |
| 112 | + studyIds = studyService |
| 113 | + .getAllStudies( |
| 114 | + null, |
| 115 | + ProjectionType.SUMMARY.name(), // force to summary so that post filter doesn't NPE |
| 116 | + PagingConstants.MAX_PAGE_SIZE, |
| 117 | + 0, |
| 118 | + null, |
| 119 | + direction.name(), |
| 120 | + null, |
| 121 | + AccessLevel.READ |
| 122 | + ) |
| 123 | + .stream() |
| 124 | + .map(CancerStudy::getCancerStudyIdentifier) |
| 125 | + .toList(); |
| 126 | + } |
| 127 | + |
| 128 | + if (projection == ProjectionType.META) { |
| 129 | + HttpHeaders responseHeaders = getMetaSamplesHeaders(keyword, studyIds); |
| 130 | + return new ResponseEntity<>(responseHeaders, HttpStatus.OK); |
| 131 | + } |
| 132 | + else { |
| 133 | + List<Sample> samples = sampleUseCases.getAllSamplesUseCase().execute( |
| 134 | + keyword, |
| 135 | + studyIds, |
| 136 | + projection, |
| 137 | + pageSize, |
| 138 | + pageNumber, |
| 139 | + sort, |
| 140 | + direction.name() |
| 141 | + ); |
| 142 | + |
| 143 | + return new ResponseEntity<>(SampleMapper.INSTANCE.toDtos(samples), HttpStatus.OK); |
| 144 | + } |
| 145 | + } |
| 146 | + |
| 147 | + @PreAuthorize("hasPermission(#sampleFilter, 'SampleFilter', T(org.cbioportal.legacy.utils.security.AccessLevel).READ)") |
| 148 | + @PostMapping( |
| 149 | + value = "/samples/fetch", |
| 150 | + consumes = MediaType.APPLICATION_JSON_VALUE, |
| 151 | + produces = MediaType.APPLICATION_JSON_VALUE |
| 152 | + ) |
| 153 | + @Operation(description = "Fetch samples by ID") |
| 154 | + @ApiResponse( |
| 155 | + responseCode = "200", |
| 156 | + description = "OK", |
| 157 | + content = @Content(array = @ArraySchema(schema = @Schema(implementation = Sample.class))) |
| 158 | + ) |
| 159 | + public ResponseEntity<List<SampleDTO>> fetchSamples( |
| 160 | + @Parameter(required = true, description = "List of sample identifiers") |
| 161 | + @Valid |
| 162 | + @RequestBody(required = false) |
| 163 | + SampleFilter sampleFilter, |
| 164 | + @Parameter(description = "Level of detail of the response") |
| 165 | + @RequestParam(defaultValue = "SUMMARY") |
| 166 | + ProjectionType projection |
| 167 | + ) { |
| 168 | + if (projection == ProjectionType.META) { |
| 169 | + HttpHeaders responseHeaders = fetchMetaSamplesHeaders(sampleFilter); |
| 170 | + return new ResponseEntity<>(responseHeaders, HttpStatus.OK); |
| 171 | + } |
| 172 | + else { |
| 173 | + List<Sample> samples = sampleUseCases.fetchSamplesUseCase().execute(sampleFilter, projection); |
| 174 | + return new ResponseEntity<>(SampleMapper.INSTANCE.toDtos(samples), HttpStatus.OK); |
| 175 | + } |
| 176 | + } |
| 177 | + |
| 178 | + @PreAuthorize("hasPermission(#studyId, 'CancerStudyId', T(org.cbioportal.legacy.utils.security.AccessLevel).READ)") |
| 179 | + @GetMapping(value = "/studies/{studyId}/samples", produces = MediaType.APPLICATION_JSON_VALUE) |
| 180 | + @Operation(description = "Get all samples in a study") |
| 181 | + @ApiResponse( |
| 182 | + responseCode = "200", |
| 183 | + description = "OK", |
| 184 | + content = @Content(array = @ArraySchema(schema = @Schema(implementation = Sample.class))) |
| 185 | + ) |
| 186 | + public ResponseEntity<List<SampleDTO>> getAllSamplesInStudy( |
| 187 | + @Parameter(required = true, description = "Study ID e.g. acc_tcga") |
| 188 | + @PathVariable |
| 189 | + String studyId, |
| 190 | + @Parameter(description = "Level of detail of the response") |
| 191 | + @RequestParam(defaultValue = "SUMMARY") |
| 192 | + ProjectionType projection, |
| 193 | + @Parameter(description = "Page size of the result list") |
| 194 | + @Max(SAMPLE_MAX_PAGE_SIZE) |
| 195 | + @Min(PagingConstants.MIN_PAGE_SIZE) |
| 196 | + @RequestParam(defaultValue = SAMPLE_DEFAULT_PAGE_SIZE) |
| 197 | + Integer pageSize, |
| 198 | + @Parameter(description = "Page number of the result list") |
| 199 | + @Min(PagingConstants.MIN_PAGE_NUMBER) |
| 200 | + @RequestParam(defaultValue = PagingConstants.DEFAULT_PAGE_NUMBER) |
| 201 | + Integer pageNumber, |
| 202 | + @Parameter(description = "Name of the property that the result list is sorted by") |
| 203 | + @RequestParam(required = false) |
| 204 | + SampleSortBy sortBy, |
| 205 | + @Parameter(description = "Direction of the sort") |
| 206 | + @RequestParam(defaultValue = "ASC") |
| 207 | + Direction direction |
| 208 | + ) throws StudyNotFoundException { |
| 209 | + if (projection == ProjectionType.META) { |
| 210 | + HttpHeaders responseHeaders = getMetaSamplesInStudyHeaders(studyId); |
| 211 | + return new ResponseEntity<>(responseHeaders, HttpStatus.OK); |
| 212 | + } else { |
| 213 | + List<Sample> samples = sampleUseCases.getAllSamplesInStudyUseCase().execute( |
| 214 | + studyId, |
| 215 | + projection, |
| 216 | + pageSize, |
| 217 | + pageNumber, |
| 218 | + sortBy == null ? null : sortBy.getOriginalValue(), |
| 219 | + direction.name() |
| 220 | + ); |
| 221 | + |
| 222 | + return new ResponseEntity<>(SampleMapper.INSTANCE.toDtos(samples), HttpStatus.OK); |
| 223 | + } |
| 224 | + } |
| 225 | + |
| 226 | + @PreAuthorize("hasPermission(#studyId, 'CancerStudyId', T(org.cbioportal.legacy.utils.security.AccessLevel).READ)") |
| 227 | + @GetMapping(value = "/studies/{studyId}/samples/{sampleId}", produces = MediaType.APPLICATION_JSON_VALUE) |
| 228 | + @Operation(description = "Get a sample in a study") |
| 229 | + @ApiResponse( |
| 230 | + responseCode = "200", |
| 231 | + description = "OK", |
| 232 | + content = @Content(schema = @Schema(implementation = Sample.class)) |
| 233 | + ) |
| 234 | + public ResponseEntity<SampleDTO> getSampleInStudy( |
| 235 | + @Parameter(required = true, description = "Study ID e.g. acc_tcga") |
| 236 | + @PathVariable |
| 237 | + String studyId, |
| 238 | + @Parameter(required = true, description = "Sample ID e.g. TCGA-OR-A5J2-01") |
| 239 | + @PathVariable |
| 240 | + String sampleId |
| 241 | + ) throws SampleNotFoundException, StudyNotFoundException { |
| 242 | + return new ResponseEntity<>( |
| 243 | + SampleMapper.INSTANCE.toSampleDTO( |
| 244 | + sampleUseCases.getSampleInStudyUseCase().execute(studyId, sampleId) |
| 245 | + ), |
| 246 | + HttpStatus.OK |
| 247 | + ); |
| 248 | + } |
| 249 | + |
| 250 | + @PreAuthorize("hasPermission(#studyId, 'CancerStudyId', T(org.cbioportal.legacy.utils.security.AccessLevel).READ)") |
| 251 | + @GetMapping(value = "/studies/{studyId}/patients/{patientId}/samples", produces = MediaType.APPLICATION_JSON_VALUE) |
| 252 | + @Operation(description = "Get all samples of a patient in a study") |
| 253 | + @ApiResponse( |
| 254 | + responseCode = "200", |
| 255 | + description = "OK", |
| 256 | + content = @Content(array = @ArraySchema(schema = @Schema(implementation = Sample.class))) |
| 257 | + ) |
| 258 | + public ResponseEntity<List<SampleDTO>> getAllSamplesOfPatientInStudy( |
| 259 | + @Parameter(required = true, description = "Study ID e.g. acc_tcga") |
| 260 | + @PathVariable |
| 261 | + String studyId, |
| 262 | + @Parameter(required = true, description = "Patient ID e.g. TCGA-OR-A5J2") |
| 263 | + @PathVariable |
| 264 | + String patientId, |
| 265 | + @Parameter(description = "Level of detail of the response") |
| 266 | + @RequestParam(defaultValue = "SUMMARY") |
| 267 | + ProjectionType projection, |
| 268 | + @Parameter(description = "Page size of the result list") |
| 269 | + @Max(SAMPLE_MAX_PAGE_SIZE) |
| 270 | + @Min(PagingConstants.MIN_PAGE_SIZE) |
| 271 | + @RequestParam(defaultValue = SAMPLE_DEFAULT_PAGE_SIZE) |
| 272 | + Integer pageSize, |
| 273 | + @Parameter(description = "Page number of the result list") |
| 274 | + @Min(PagingConstants.MIN_PAGE_NUMBER) |
| 275 | + @RequestParam(defaultValue = PagingConstants.DEFAULT_PAGE_NUMBER) |
| 276 | + Integer pageNumber, |
| 277 | + @Parameter(description = "Name of the property that the result list is sorted by") |
| 278 | + @RequestParam(required = false) |
| 279 | + SampleSortBy sortBy, |
| 280 | + @Parameter(description = "Direction of the sort") |
| 281 | + @RequestParam(defaultValue = "ASC") Direction direction |
| 282 | + ) throws PatientNotFoundException, StudyNotFoundException { |
| 283 | + if (projection == ProjectionType.META) { |
| 284 | + HttpHeaders responseHeaders = getMetaSamplesOfPatientInStudyHeaders(studyId, patientId); |
| 285 | + return new ResponseEntity<>(responseHeaders, HttpStatus.OK); |
| 286 | + } else { |
| 287 | + List<Sample> samples = sampleUseCases.getAllSamplesOfPatientInStudyUseCase().execute( |
| 288 | + studyId, |
| 289 | + patientId, |
| 290 | + projection, |
| 291 | + pageSize, |
| 292 | + pageNumber, |
| 293 | + sortBy == null ? null : sortBy.getOriginalValue(), |
| 294 | + direction.name() |
| 295 | + ); |
| 296 | + |
| 297 | + return new ResponseEntity<>(SampleMapper.INSTANCE.toDtos(samples), HttpStatus.OK); |
| 298 | + } |
| 299 | + } |
| 300 | + |
| 301 | + private HttpHeaders fetchMetaSamplesHeaders( |
| 302 | + SampleFilter sampleFilter |
| 303 | + ) { |
| 304 | + HttpHeaders httpHeaders = new HttpHeaders(); |
| 305 | + BaseMeta baseMeta = sampleUseCases.fetchMetaSamplesUseCase().execute(sampleFilter); |
| 306 | + httpHeaders.add(HeaderKeyConstants.TOTAL_COUNT, baseMeta.getTotalCount().toString()); |
| 307 | + |
| 308 | + return httpHeaders; |
| 309 | + } |
| 310 | + |
| 311 | + private HttpHeaders getMetaSamplesHeaders(String keyword, List<String> studyIds) { |
| 312 | + HttpHeaders httpHeaders = new HttpHeaders(); |
| 313 | + httpHeaders.add( |
| 314 | + HeaderKeyConstants.TOTAL_COUNT, |
| 315 | + sampleUseCases.getMetaSamplesUseCase().execute(keyword, studyIds).getTotalCount().toString() |
| 316 | + ); |
| 317 | + |
| 318 | + return httpHeaders; |
| 319 | + } |
| 320 | + |
| 321 | + private HttpHeaders getMetaSamplesInStudyHeaders(String studyId) throws StudyNotFoundException { |
| 322 | + HttpHeaders httpHeaders = new HttpHeaders(); |
| 323 | + httpHeaders.add( |
| 324 | + HeaderKeyConstants.TOTAL_COUNT, |
| 325 | + sampleUseCases.getMetaSamplesInStudyUseCase().execute(studyId).getTotalCount().toString() |
| 326 | + ); |
| 327 | + |
| 328 | + return httpHeaders; |
| 329 | + } |
| 330 | + |
| 331 | + private HttpHeaders getMetaSamplesOfPatientInStudyHeaders( |
| 332 | + String studyId, |
| 333 | + String patientId |
| 334 | + ) throws StudyNotFoundException, PatientNotFoundException |
| 335 | + { |
| 336 | + HttpHeaders httpHeaders = new HttpHeaders(); |
| 337 | + httpHeaders.add( |
| 338 | + HeaderKeyConstants.TOTAL_COUNT, |
| 339 | + sampleUseCases.getMetaSamplesOfPatientInStudyUseCase().execute(studyId, patientId).getTotalCount().toString() |
| 340 | + ); |
| 341 | + |
| 342 | + return httpHeaders; |
| 343 | + } |
| 344 | +} |
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