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README.md

CellAgent (CellTypeAgent)

ID: biomedical.genomics.cell_annotation Version: 1.1.0 Status: Integrated & Downloaded Category: Genomics / Single-Cell Annotation


Overview

CellTypeAgent is an LLM-driven framework for automated cell type annotation in scRNA-seq data. It interprets marker genes, assigns labels, and generates explanations with confidence scores.


Inputs

Field Type Notes
markers list[str] Marker genes per cluster
species str human or mouse
tissue str Optional tissue context
reference str Optional atlas reference

Outputs

  • Cell type labels per cluster
  • Confidence score and evidence markers
  • Suggested ambiguous or mixed identities

Quick Start

cd repo
pip install -r requirements.txt
python repo/main.py --data your_data.h5ad

Guardrails

  • Do not over-specify cell types without marker support.
  • Use tissue context to resolve ambiguous marker sets.
  • Flag clusters with mixed signatures for manual review.

References