Generated: 2026-02-12 16:35:23 Protein ID: P53350 Organism: Homo sapiens
| Pathway Name | Pathway ID | Species |
|---|---|---|
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | Homo sapiens |
| Polo-like kinase mediated events | R-HSA-156711 | Homo sapiens |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | Homo sapiens |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | Homo sapiens |
| Phosphorylation of the APC/C | R-HSA-176412 | Homo sapiens |
| Phosphorylation of Emi1 | R-HSA-176417 | Homo sapiens |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | Homo sapiens |
| Separation of Sister Chromatids | R-HSA-2467813 | Homo sapiens |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | Homo sapiens |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | Homo sapiens |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | Homo sapiens |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | Homo sapiens |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | Homo sapiens |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | Homo sapiens |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | Homo sapiens |
Top Pathway Details: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Reactions/Subpathways: 4
| Event Name | Type |
|---|---|
| Mad1 binds kinetochore | Reaction |
Total: 29 top-level pathways
| Pathway Name | Pathway ID |
|---|---|
| Autophagy | R-HSA-9612973 |
| Cell Cycle | R-HSA-1640170 |
| Cell-Cell communication | R-HSA-1500931 |
| Cellular responses to stimuli | R-HSA-8953897 |
| Chromatin organization | R-HSA-4839726 |
| Circadian clock | R-HSA-9909396 |
| Developmental Biology | R-HSA-1266738 |
| Digestion and absorption | R-HSA-8963743 |
| Disease | R-HSA-1643685 |
| DNA Repair | R-HSA-73894 |
| DNA Replication | R-HSA-69306 |
| Drug ADME | R-HSA-9748784 |
| Extracellular matrix organization | R-HSA-1474244 |
| Gene expression (Transcription) | R-HSA-74160 |
| Hemostasis | R-HSA-109582 |
| Immune System | R-HSA-168256 |
| Metabolism | R-HSA-1430728 |
| Metabolism of proteins | R-HSA-392499 |
| Metabolism of RNA | R-HSA-8953854 |
| Muscle contraction | R-HSA-397014 |